Mohamad G. Ghosn

1. Mentioned In 18 Articles

2. Monitoring of Molecular Permeability in Tissues Using Optical Coherence Tomography

   Explore Article Optical Coherence Tomography News (Oct 25 2009)

   ...references below. Courtesy Dr. Kirill Larin. For better viewing click "Full Screen". [1] M. G. Ghosn, S. H. Syed, N. A. Befrui, M. Leba, A. Vijayananda, N. Sudheendran, and K. V. Larin, "Quantifi... (Read Full Article)
   

   Comment on Article Mentions:   Kirill V. Larin   Mohamad G. Ghosn   Saratov State University

3. Monitoring of glucose permeability in monkey skin in vivo using Optical Coherence Tomography

   Explore Article www3.interscience.wiley.com (Oct 12 2009) Dermatology , Glucose

   Topical trans-dermal delivery of drugs has proven to be a promising route for treatment of many dermatological diseases. The aim of this study is to monitor and quantify the permeability rate of glucose solutions in rhesus monkey skin noninvasively in vivo as a primate model for drug diffusion. A time-domain Optical Coherence Tomography (OCT) system was used to image the diffusion of glucose in the skin of anesthetized monkeys for ... (Read Full Article)
   

   Comment on Article Mentions:   Kirill V. Larin   University of Houston   Saratov State University

4. Quantification of molecular diffusion in arterial tissues with optical coherence tomography and fluorescence microscopy

   Explore Article SpringerLink Home (Jun 6 2009)

   Abstract Alternations in vascular permeability for different molecules, drugs, and contrast agents might be a significant early marker of development of various diseases such as atherosclerosis. However, up to date experimental studies of molecular diffusion across vascular wall have been limited. Recently, we demonstrated that the Optical Coherence Tomography (OCT) technique could be applied for noninvasive and nondestructive quantification of molecular diffusion in different biological tissues. However, the viability of ... (Read Full Article)
   

   Comment on Article Mentions:   Saratov State University   University of Houston   Kirill V. Larin

5. Effect of temperature on permeation of low-density lipoprotein particles through human carotid artery tissues

   Explore Article www3.interscience.wiley.com (Mar 11 2009) Cardiology , Glucose

   Quantification of the diffusion of small molecules and large lipid transporting lipoproteins across arterial tissues could be useful in elucidating the mechanism(s) of atherosclerosis. Optical coherence tomography (OCT) was used to determine the effect of temperature on the rate of diffusion of glucose and low-density lipoproteins (LDL) in human carotid endarterectomy tissue in vitro. The permeability rate for glucose was calculated to be (3.51 ± 0.27) × 10-5 cm/s (n ... (Read Full Article)
   

   Comment on Article Mentions:   Kirill V. Larin   University of Houston   Mohamad G. Ghosn

6. The nonlinear relationship between concentration of analyte and its permeability coefficient in ocular tissues

   Explore Article SPIE Digital Library (Feb 23 2009) Glucose

   ...s VI Conference Chairs: Valery V. Tuchin, Lihong V. Wang, Donald D. Duncan ABSTRACT REFERENCES (14) Mohamad G. Ghosn Univ. of Houston (USA) Valery V. Tuchin Saratov State Univ. (Russian Federation) Kirill V. Larin Un... (Read Full Article)
   

   Comment on Article Mentions:   Kirill V. Larin   Valery V. Tuchin   Mohamad G. Ghosn

7. Quantifying the effect of milli-molar glucose concentration on thickness of rabbit cornea with optical coherence tomography

   Explore Article SPIE Digital Library (Feb 20 2009) Glucose , Ophthalmology

   ...itle: Optical Diagnostics and Sensing IX Conference Chairs: Gerard L. Coté ABSTRACT REFERENCES (11) Mohamad G. Ghosn, Michael Leba, and Astha Vijayananda Univ. of Houston (USA) Rafat R. Ansari Univ. of Texas School o... (Read Full Article)
   

   Comment on Article Mentions:   Kirill V. Larin   Mohamad G. Ghosn   University of Houston

8. Optical coherence tomography in estimating molecular diffusion of drugs and analytes in ocular tissues

   Explore Article SPIE Digital Library (Feb 18 2009) Ophthalmology

   Aside from other ocular drug delivery methods, topical application and follow up drug diffusion through the cornea and sclera of the eye remain the favored method, as they impose the least pain and discomfort to the patient. However, this delivery route suffers from the low permeability of epithelia ... [Proc. SPIE 7163, 71631H (2009)] published Wed Feb 18, 2009. (Read Full Article)
   

   Comment on Article Mentions:   Valery V. Tuchin   Mohamad G. Ghosn   Kirill V. Larin

9. Live imaging of blood flow in mammalian embryos using Doppler swept-source optical coherence tomography

   Explore Article SPIE Digital Library (Dec 21 2008) Developmental Biology , Doppler

   Irina V. Larina, Narendran Sudheendran, Mohamad Ghosn et al. Studying hemodynamic changes during early mammalian embryonic development is critical for f... (Read Full Article)
   

   Comment on Article Mentions:   Alex E. Cable   Thorlabs   Kirill V. Larin

10. Assessing molecular diffusion in tissues using optical coherence tomography

    Explore Article Home: SPIE.org (Jun 20 2008)

    ...development of novel therapeutic agents, drug delivery systems, and diagnostic tests. Kirill Larin, Mohamad Ghosn, and Valery Tuchin Advanced imaging near the surface of tissues could assist the development of nov... (Read Full Article)
    

    Comment on Article Mentions:   Kirill V. Larin   University of Houston   Valery V. Tuchin

11. Concentration effect on the diffusion of glucose in ocular tissues

    Explore Article ScienceDirect (Jun 17 2008)

    In this study, optical coherence tomography (OCT) was utilized in the functional imaging of glucose diffusion through scleral tissues. Permeability coefficients for different concentrations of glucose were quantified nondestructively. Obtained results indicate an inverse proportionality between the permeability coefficient and the concentration of the analyte in epithelial tissues: in-depth diffusion of solutions with lower glucose concentration was faster than those with a higher concentration. The permeability coefficient decreased from (1.67±0.17)×10−5 ... (Read Full Article)
    

    Comment on Article Mentions:   Kirill V. Larin   University of Houston   Saratov State University

12. The effect of solution concentration on diffusion in scleral tissues

    Explore Article SPIE Digital Library (Jun 9 2008) Glucose , Ophthalmology

    Mohamad G. Ghosn, Esteban F. Carbajal, Natasha A. Befrui et al. The calculation of permeability coefficient of anal... (Read Full Article)
    

    Comment on Article Mentions:   Mohamad G. Ghosn   Kirill V. Larin   University of Houston

13. Differential permeability rate and percent clearing of glucose in different regions in rabbit sclera

    Explore Article SPIE Digital Library (Apr 21 2008) Glucose , Ophthalmology

    Mohamad G. Ghosn, Esteban F. Carbajal, Natasha A. Befrui et al. Imaging of biological tissues with optical coheren... (Read Full Article)
    

    Comment on Article Mentions:   Saratov State University   Mohamad G. Ghosn   University of Houston

14. Permeability of hyperosmotic agent in normal and atherosclerotic vascular tissues

    Explore Article SPIE Digital Library (Feb 28 2008) Cardiology

    ...05 (2008); doi:10.1117/1.2870153 Published 28 February 2008 ABSTRACT REFERENCES (9) CITING ARTICLES Mohamad G. Ghosn,^1 Esteban F. Carbajal,^1 Natasha A. Befrui,^1 Armando Tellez,^2 Juan F. Granada,^3 and Kirill V. L... (Read Full Article)
    

    Comment on Article Mentions:   Kirill V. Larin   University of Houston   Mohamad G. Ghosn

15. Quantifying permeability of glucose in normal and atherosclerotic pig aorta in vitro using optical coherence tomography

    Explore Article SPIE Digital Library (Feb 18 2008) Cardiology , Glucose

    Mohamad G. Ghosn, Esteban Carbajal, Natasha Befrui et al. High in-depth resolution imaging, such as Optical Coheren... (Read Full Article)
    

    Comment on Article Mentions:   Mohamad G. Ghosn   Kirill V. Larin   University of Houston

16. Quantification of glucose diffusion in arterial tissues by using optical coherence tomography

    Explore Article www3.interscience.wiley.com (Dec 21 2006) Cardiology , Glucose

    Several investigations suggest that the early stages of atherosclerosis are modulated by the selective permeability of the vascular tissue to pro-inflammatory molecules of different molecular weights. Up to date, a few experiments have been performed to study the permeability of arterial tissue to different molecules. This is primarily due to an absence of an experimental technique capable of depth-resolved, accurate and sensitive assessment of arterial permeability. In this paper, we ... (Read Full Article)
    

    Comment on Article Mentions:   Kirill V. Larin   University of Houston   Saratov State University

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