Ludwig Maximilians Universität München

1. Mentioned In 38 Articles

2. Tracking Progression with Spectral-Domain Optical Coherence Tomography in Geographic Atrophy Caused by Age-Related Macular Degeneration

   Explore Article iovs.org (Jul 22 2010) Ophthalmology

   Purpose. To investigate, with the use of spectral-domain optical coherence tomography (SD-OCT), microstructural alterations over time in eyes with progressive geographic atrophy (GA) due to age-related macular degeneration. Methods. Forty-six eyes of 26 patients (median age, 77.9 years [interquartile range (IQR), 71.8–81.0]) with GA without evidence of active or previous neovascular disease at baseline were examined by simultaneous confocal scanning laser ophthalmoscopy (cSLO) and SD-OCT. Serial examinations with alignment of ... (Read Full Article)
   

   Comment on Article Mentions:   University of Oxford   Frank G. Holz   Ludwig Maximilians Universität München

3. Fourier domain mode-locked swept source
at 1050 nm based on a tapered amplifier

   Explore Article opticsinfobase.org (Jul 12 2010) Tunable Sources

   While swept source optical coherence tomography (OCT) in the 1050 nm range is promising for retinal imaging, there are certain challenges. Conventional semiconductor gain media have limited output power, and the performance of high-speed Fourier domain mode-locked (FDML) lasers suffers from chromatic dispersion in standard optical fiber. We developed a novel light source with a tapered amplifier as gain medium, and investigated the FDML performance comparing two fiber delay lines ... (Read Full Article)
   

   Comment on Article Mentions:   Peter E. Andersen   Wolfgang Wieser   Thomas Klein

4. Multi-Megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second

   Explore Article opticsinfobase.org (Jun 23 2010) Tunable Sources

   We present ultra high speed optical coherence tomography (OCT) with multi-megahertz line rates and investigate the achievable image quality. The presented system is a swept source OCT setup using a Fourier domain mode locked (FDML) laser. Three different FDML-based swept laser sources with sweep rates of 1, 2.6 and 5.2MHz are compared. Imaging with 4 spots in parallel quadruples the effective speed, enabling depth scan rates as high as 20.8 ... (Read Full Article)
   

   Comment on Article Mentions:   Wolfgang Wieser   Thomas Klein   Benjamin R. Biedermann

5. Measurement of epithelial thickness within the oral cavity using optical coherence tomography (OCT)

   Explore Article SPIE Digital Library (Mar 2 2010) Oncology , Otolaryngology

   Optical coherence tomography (OCT) is a promising method in the early diagnosis of oral cavity cancer. The objective of the present study is to determine normal values of epithelial thickness in the oral cavity, as no such data are to be found in the literature. In healthy test persons, epithelial thickness of the oral mucosa was determined with the help of OCT separately for each side at nine different locations. ... (Read Full Article)
   

   Comment on Article Mentions:   Ludwig Maximilians Universität München

6. FDML swept source at 1060 nm using a tapered amplifier

   Explore Article SPIE Digital Library (Feb 19 2010) Tunable Sources

   We present a novel frequency-swept light source working at 1060nm that utilizes a tapered amplifier as gain medium. These devices feature significantly higher saturation power than conventional semiconductor optical amplifiers and can thus improve the limited output power of swept sources in this wavelength range. We demonstrate that a tapered amplifier can be integrated into a fiber-based swept source and allows for high-speed FDML operation. The developed light source operates ... (Read Full Article)
   

   Comment on Article Mentions:   Micron Optics   Wolfgang Wieser   Thomas Klein

7. Optical coherence tomography of the upper urinary tract: Review of initial experience ex vivo and in vivo

   Explore Article ScienceDirect (Feb 3 2010) Urology

   Diagnostic imaging of the upper urinary tract is a cumbersome process that involves a multitude of different imaging modalities, including ultrasonography, conventional radiography, X-ray fluoroscopy (retrograde and antegrade ureteropyelography), endoscopy (cystoscopy and ureterorenoscopy) without or with biopsy, multi-detector-row computed tomography (MDCT), and magnetic resonance imaging (MRI). However, these modalities leave a diagnostic gap because they cannot demonstrate different layers of the wall of the upper urinary tract. Recent research shows ... (Read Full Article)
   

   Comment on Article Mentions:   Siemens   Ludwig Maximilians Universität München

8. Fourier Domain Mode Locking (FDML): Wavelength Swept Lasers for Ultrahigh Speed Optical Coherence Tomography

   Explore Article SpringerLink Home (Jan 4 2010) Tunable Sources

   Optical coherence tomography (OCT) is a novel, depth resolved biomedical imaging technique, providing highresolution, cross-sectional and three-dimensional images of tissue microstructure. The application of OCT systems based on rapidly wavelength swept, narrow band light sources, referred to as “swept source OCT” or “optical frequency domain imaging”, offers several potential advantages compared to high speed OCT systems based on fast spectrometers. The advent of Fourier domain mode locked (FDML) lasers as ... (Read Full Article)
   

   Comment on Article Mentions:   Ludwig Maximilians Universität München   Robert A. Huber

9. A theoretical description of Fourier domain mode locked lasers

   Explore Article opticsinfobase.org (Dec 16 2009) Tunable Sources

   Abstract The first theoretical model of Fourier domain mode locking operation is presented. A specially tailored dynamic equation in a moving spectral reference frame is derived, enabling efficient numerical treatment, despite the broad laser spectrum and the extremely long cavity. The excellent agreement of the presented theory with experiment over a wide range of operation parameters enables a quantitative assessment of the relevant physical effects, such as the spectral loss ... (Read Full Article)
   

   Comment on Article Mentions:   Benjamin R. Biedermann   Robert A. Huber   Ludwig Maximilians Universität München

10. Cascaded Wavelength Swept Amplified Spontaneous Emission Source for Optical Coherence Tomography

    Explore Article Optical Coherence Tomography News (Dec 6 2009) Tunable Sources

    Feature Of The Week 12/6/09: Due to increasing interest in Optical Coherence Tomography (OCT) using wavelength swept lasers (SS-OCT), huge efforts have been made by both research and commercial organizations around the world to push the performance of such sources and with it OCT system capabilities. This includes sweep repetition rate, power, new wavelengths, coherence length, and more. One of the drawbacks of standard wavelength-swept lasers is the fact that ... (Read Full Article)
    

    Comment on Article Mentions:   Robert A. Huber   Wolfgang Wieser   Ludwig Maximilians Universität München

11. Amadeus® II microkeratome: optimizing microkeratome settings for high flap accuracy using optical low coherence reflectometry

    Explore Article eur-j-ophthalmol.com (Nov 3 2009) Ophthalmology

    Purpose. To investigate the impact of various experimental microkeratome settings and blade reuse on the accuracy of the flap thickness created with the new Amadeus® II microkeratome (SIS, Ziemer Ophthalmic, Port, Switzerland). Methods. In this prospective study, 120 porcine eyes were used to create corneal flaps with the Amadeus® II using 2 different cutting heads (140 µm, 160 µm) with the Surepass® blade. Using each blade twice, a head advance ... (Read Full Article)
    

    Comment on Article Mentions:   Ludwig Maximilians Universität München

12. Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography

    Explore Article PLoS ONE (Oct 20 2009) Ophthalmology

    Background Optical coherence tomography (OCT) is a novel method of retinal in vivo imaging. In this study, we assessed the potential of OCT to yield histology-analogue sections in mouse models of retinal degeneration. Methodology/Principal Findings We achieved to adapt a commercial 3rd generation OCT system to obtain and quantify high-resolution morphological sections of the mouse retina which so far required in vitro histology. OCT and histology were compared in models ... (Read Full Article)
    

    Comment on Article Mentions:   University of Toronto   University of Zurich   Ludwig Maximilians Universität München

13. Wavelength swept amplified spontaneous emission source

    Explore Article opticsinfobase.org (Oct 2 2009) Tunable Sources

    We present a new, alternative approach to realize a wavelength swept light source with no fundamental limit to sweep speed. Amplified spontaneous emission (ASE) light alternately passes a cascade of optical gain elements and tunable optical bandpass filters. We show that for high sweep speeds, the control signal for the different filters has to be applied with a defined, precise phase delay on the order of nanoseconds, to compensate for ... (Read Full Article)
    

    Comment on Article Mentions:   Robert A. Huber   Wolfgang Wieser   Ludwig Maximilians Universität München

14. Optics made to measure: Joint spin-off of LMU Munich and MPG established

    Explore Article Innovationen, Forschung, Wissenschaft (Sep 18 2009) Other Business News

    If you are in the business of developing high-speed electronic components, it pays not to lose sight of the electrons. To keep track of them you will need to use dedicated optical elements, such as those now on offer from UltraFast Innovations GmbH. The new company, which has just been founded by researchers at Ludwig-Maximilians-Universität (LMU) in Munich and the Max Planck Society (MPG), manufactures specialized mirrors and other optical ... (Read Full Article)
    

    Comment on Article Mentions:   Ludwig Maximilians Universität München

15. In vitro examination of suspicious oral lesions using optical coherence tomography

    Explore Article ScienceDirect (Sep 1 2009) Dentistry

    Publication year: 2009Source: British Journal of Oral and Maxillofacial Surgery, In Press, Corrected Proof, Available online 1 September 2009Waseem, Jerjes , Tahwinder, Upile , Brendan, Conn , Zaid, Hamdoon , Christian S., Betz , ...We compared findings of optical coherence tomography (OCT) with histopathological results of suspicious oral lesions to assess the feasibility of using OCT to identify malignant tissue. Thirty-four oral lesions from 27 patients had swept-source frequency-domain OCT. ... (Read Full Article)
    

    Comment on Article Mentions:   Lantis Laser   Imperial College London   University College London

16. Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range

    Explore Article opticsinfobase.org (Aug 6 2009) Ophthalmology , Tunable Sources

    We present an application of in vivo anterior segment imaging of the human eye with an ultrahigh speed swept source OCT instrument. For this purpose, a dedicated OCT system was designed and constructed. This instrument enables axial zooming by automatic reconfiguration of spectral sweep range; an enhanced imaging range mode enables imaging of the entire anterior segment while a high axial resolution mode provides detailed morphological information of the chamber ... (Read Full Article)
    

    Comment on Article Mentions:   Maciej Wojtkowski   Andrzej A. Kowalczyk   Michalina Góra

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