1. Mentioned In 19 Articles

  2. 3-Dimensional Optical Coherence Tomography Assessment of Jailed Side Branches by Bioresorbable Vascular Scaffolds: A Proposal for Classification

    Explore Article interventions.onlinejacc.org (Aug 16 2010)

    3-Dimensional Optical Coherence Tomography Assessment of Jailed Side Branches by Bioresorbable Vascular Scaffolds: A Proposal for Classification Objectives The purpose of this study is to assess jailing of side branches (SB) by the everolimus-eluting, bioresorbable vascular scaffold (BVS) with 3-dimensional (3D) optical coherence tomography (OCT) reconstruction. Background Because BVS struts at the SB orifice are suspected of being bioresorbed and/or forming a neointimal bridge, OCT has been used to evaluate the struts in detail at that particular site. Our understanding of the 3D relationship of the strut ... (Read Full Article)

    Comment on Article Mentions:   LightLab Imaging   Patrick W. Serruys   Evelyn Regar

  3. Relation between plaque type and dissections at the edges after stent implantation: An optical coherence tomography study

    Explore Article International Journal of Cardiology (May 13 2010)

    Relation between plaque type and dissections at the edges after stent implantation: An optical coherence tomography study Abstract: Background: Stent implantation can create vessel damage such as edge dissections. The objectives were i) to evaluate the frequency of edge dissections after stenting visible by intracoronary optical coherence tomography (OCT) in comparison with angiography. ii) to assess with OCT the plaque type left at the stent edges after implantation, and iii) to study whether there is an association between plaque type and dissections at stent edges.Methods: Seventy-three consecutive ... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Evelyn Regar   Hector M. Garcia-Garcia

  4. Combined optical coherence tomography and intravascular ultrasound radio frequency data analysis for plaque characterization. Classification accuracy of human coronary plaques in vitro

    Explore Article SpringerLink Home (Apr 15 2010)

    Combined optical coherence tomography and intravascular ultrasound radio frequency data analysis for plaque characterization. Classification accuracy of human coronary plaques in vitro This study was performed to characterize coronary plaque types by optical coherence tomography (OCT) and intravascular ultrasound (IVUS) radiofrequency (RF) data analysis, and to investigate the possibility of error reduction by combining these techniques. Intracoronary imaging methods have greatly enhanced the diagnostic capabilities for the detection of high-risk atherosclerotic plaques. IVUS RF data analysis and OCT are two techniques focusing on plaque morphology and composition. Regions of interest were selected ... (Read Full Article)

    Comment on Article Mentions:   Thoraxcenter at Erasmus University Medical Center   LightLab Imaging   Patrick W. Serruys

  5. Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

    Explore Article Netherlands Heart Journal (Dec 2 2009)

    Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient mu(t) distinguishes different tissue ... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Evelyn Regar   Thoraxcenter at Erasmus University Medical Center

  6. How should I treat a complex Post-CABG patient?

    Explore Article eurointervention.org (Nov 18 2009)

    How should I treat a complex Post-CABG patient? A 69 year old man was admitted with unstable angina (Class IIB). He had a history of chronic renal impairment, diabetes melltus, hypertension and coronary bypass surgery in 1997 (LIMA graft to the LAD and diagonal branch, saphenous vein grafts to the RCA and first marginal branch of LCx). Diagnostic coronary angiogram revealed: occlusion of the proximal LCx and RCA. (Read Full Article)

    Comment on Article Mentions:   LightLab Imaging   Patrick W. Serruys   Hector M. Garcia-Garcia

  7. Optical Coherence Tomography Assessment Of The Acute Effects Of Stent Implantation On The Vessel Wall. A Systematic Quantitative Approach

    Explore Article Heart (Aug 9 2009)

    Objective: To observe and characterise vessel injury post-stenting using optical coherence tomography (OCT), to propose a systematic OCT classification for periprocedural vessel trauma, to evaluate its frequency in stable vs unstable patients and to assess its clinical impact during the hospitalization period. Setting: stenting causes vessel injury. Design and interventions: All consecutive patients in whom OCT was performed after stent implantation were included in the study. Qualitative and quantitative assessment ... (Read Full Article)

    Comment on Article Mentions:   Thoraxcenter at Erasmus University Medical Center   Patrick W. Serruys   Evelyn Regar

  8. Virtual histology and optical coherence tomography: from research to a broad clinical application

    Explore Article Heart (Jul 27 2009)

    Invasive coronary imaging techniques have improved our understanding of atherosclerosis and helped us to evaluate the effectiveness of new drugs and new intravascular devices. We have adopted and integrated them rapidly into our clinical decision making process in the catheterisation laboratory. So far, only significant lesions in the coronary angiogram have been treated either by percutaneous coronary intervention (PCI) or coronary bypass artery grafting (CABG), while normal looking coronary segments ... (Read Full Article)

    Comment on Article Mentions:   Thoraxcenter at Erasmus University Medical Center   Patrick W. Serruys   Evelyn Regar

  9. Optical coherence tomography patterns of stent restenosis

    Explore Article American Heart Journal (Jul 23 2009)

    Background Stent restenosis is an infrequent but poorly understood clinical problem in the drug-eluting stent era. The aim of the study was to evaluate the morphologic characteristics of stent restenosis by optical coherence tomography (OCT). Methods Patients (n = 24, 25 vessels) presenting with angiographically documented stent restenosis were included. Quantitative OCT analysis consisted of lumen and stent area measurement and calculation of restenotic tissue area and burden. Qualitative restenotic ... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Evelyn Regar   Hector M. Garcia-Garcia

  10. Reproducibility of quantitative optical coherence tomography for stent analysis

    Explore Article eurointervention.org (Jul 5 2009)

    Aims: To assess the inter- and intra- observer reproducibility for strut count, strut apposition and strut tissue coverage measurements with optical coherence tomography (OCT).Methods and results: Ten drug-eluting stents (244 frames, 1712 struts) imaged with OCT nine months after implantation were analysed by two independent analysts. One of the analysts repeated the analysis of five stents (120 frames, 795 struts) one week later. Offline analysis was performed with the proprietary ... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Evelyn Regar   Hector M. Garcia-Garcia

  11. The Risk of Stent Thrombosis in Patients With Acute Coronary Syndromes Treated With Bare-Metal and Drug-Eluting Stents

    Explore Article interventions.onlinejacc.org (Jun 16 2009)

    ...e stent thrombosis are more pronounced in stable patients Neville Kukreja, MA, Yoshinobu Onuma, MD, Hector M. Garcia-Garcia, MSc, MD, Joost Daemen, MD, Ron van Domburg, MD, PhD, Patrick W. Serruys, MD, PhD* on behalf of the... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Hector M. Garcia-Garcia   Thoraxcenter at Erasmus University Medical Center

  12. Incomplete Stent Apposition and Delayed Tissue Coverage Are More Frequent in Drug-Eluting Stents Implanted During Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Than in Drug-Eluting Stents Implanted for Stable/Un

    Explore Article interventions.onlinejacc.org (May 17 2009)

    ...ered struts at follow-up. Nieves Gonzalo, MD, Peter Barlis, MBBS, MPH, Patrick W. Serruys, MD, PhD, Hector M. Garcia-Garcia, MD, MSc, Yoshinobu Onuma, MD, Jurgen Ligthart, BSc, Evelyn Regar, MD, PhD* Thoraxcenter, Erasmus M... (Read Full Article)

    Comment on Article Mentions:   Peter Barlis   University of Melbourne   Patrick W. Serruys

  13. First case of stenting of a vulnerable plaque in the Secritt I trial—the dawn of a new era?

    Explore Article Nature Publishing Group (Apr 22 2009)

    Background. A 63-year-old man presented with class II anginal symptoms. Investigations. Cardiac catheterization, intravascular ultrasound (IVUS) virtual histology, optical coherence tomography and off-line palpography. Diagnosis. The patient was diagnosed as having a culprit lesion in the left circumflex artery and a vulnerable plaque in the left anterior descending artery. Management. The culprit lesion was treated with two overlapping drug-eluting stents. The vulnerable plaque was then treated with a self-expanding stent ... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Evelyn Regar   Hector M. Garcia-Garcia

  14. In Vivo Assessment of High-Risk Coronary Plaques at Bifurcations With Combined Intravascular Ultrasound and Optical Coherence Tomography

    Explore Article imaging.onlinejacc.org (Apr 12 2009)

    ...e likely to contain thin fibrous cap and a greater proportion of necrotic core. Nieves Gonzalo, MD, Hector M. Garcia-Garcia, MD, MSc, Evelyn Regar, MD, PhD, Peter Barlis, MBBS, MPH, Jolanda Wentzel, PhD, Yoshinobu Onuma, MD... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Evelyn Regar   Thoraxcenter at Erasmus University Medical Center

  15. A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods

    Explore Article TheLancet.com (Mar 15 2009)

    Background: Drug-eluting metallic coronary stents predispose to late stent thrombosis, prevent late lumen vessel enlargement, hinder surgical revascularisation, and impair imaging with multislice CT. We assessed the safety of the bioabsorbable everolimus-eluting stent (BVS). Methods: 30 patients with a single de-novo coronary artery lesion were followed up for 2 years clinically and with multiple imaging methods: multislice CT, angiography, intravascular ultrasound, derived morphology parameters (virtual histology, palpography, and echogenicity), and ... (Read Full Article)

    Comment on Article Mentions:   Evelyn Regar   Nico Bruining   Yoshinobu Onuma

  16. Quantitative Ex Vivo and In Vivo Comparison of Lumen Dimensions Measured by Optical Coherence Tomography and Intravascular Ultrasound in Human Coronary Arteries

    Explore Article Elsevier (Feb 13 2009)

    Quantitative Ex Vivo and In Vivo Comparison of Lumen Dimensions Measured by Optical Coherence Tomography and Intravascular Ultrasound in Human Coronary Arteries Introduction and objectives. The relationship between the lumen dimensions obtained in human coronary arteries using intravascular ultrasound (IVUS) and those obtained using optical coherence tomography (OCT) is not well understood. The objectives were to compare the lumen measurement obtained ex vivo in human coronary arteries using IVUS, OCT, and histomorphometry, and in vivo in patients using IVUS and OCT with and without balloon occlusion. Methods. Ex vivo study: the lumen ... (Read Full Article)

    Comment on Article Mentions:   LightLab Imaging   Patrick W. Serruys   Lightlab ImageWire

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