Stephen A. Boppart

About Stephen A. Boppart

Stephen A. Boppart is a professor in the Biophotonics Imaging Laboratory at the University of Illinois Urbana Champaign.  Dr. Boppart received his Ph.D. from the Massachusetts Institute of Technology in 1998, followed by a M.D. from Harvard Medical School in 2000. Currently Prof. Boppart is a full-time faculty member in the Beckman Institute Nanoelectronics and Biophotonics Group as well as an associate professor in the UIUC Department of Electrical and Computer Engineering and the Bioengineering Department. In January 2007, he was named the Founding Director of the Mills Breast Cancer Institute at Carle Foundation Hospital. Dr. Boppart is also a Clinical Research Physician in the UI College of Medicine-Urbana. His fields of professional interest include optical imaging (specifically in Optical Coherence Tomography) and biophotonics in medicine and biology.

Quotes

1. “ And this is found a day later after the surgery has ended....It means that the patient has to come back for another procedure, with all the risks and costs associated with that, and all the anxiety. Another downside for the patient is if there are any tumor cells left behind. These patients are likely to relapse, as there is a fairly high local recurrence rate of tumors that grow back in that area. ”

   In Optics may speed breast cancer diagnosis

2. “ Intraoperative OCT has the potential to provide diagnostically useful information about margin status in real time, at the point of care, rather than relying on postoperative histopathology. ”

   In Optical Coherence Tomography Identifies Surgical Margins for Breast Cancer Intraoperatively

3. “ The imaging depth was equivalent to the tissue depth that pathologists typically examine postoperatively to determine if the margin is negative, close or positive...Image features could also be used to identify structures such as surface blood or cauterised tissue and distinguish these image artifacts from normal and tumour tissue ”

   In Optical Coherence Tomography Identifies Surgical Margins for Breast Cancer Intraoperatively

1. Mentioned In 56 Articles

2. Measurements of Biomechanics by Dynamic Optical Coherence Elastography

   Explore Article Optical Coherence Tomography News (Feb 21 2010)

   ...t from remote excitation and the ability to maintain a sterile in vivo environment Xing Liang and Stephen A. Boppart Beckman Institute of Advanced Science and Technology University of Illinois at Urbana-Champaign F......oc. SPIE 68471B (2008). 3. X. Liang, et al. Opt. Express 16, 11052-11065 (2008). 4. X. Liang and S. A. Boppart, IEEE T. Bio-Med. Eng. (2009). 5. X. Liang, et al. Opt. Lett. 34, 2894-2896 (2009). (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Xing Liang

3. Resonant acoustic spectroscopy of soft tissues using embedded magnetomotive nanotransducers and optical coherence tomography

   Explore Article Institute of Physics (Feb 1 2010)

   ...1088/0031-9155/55/4/019 Help PDF (808 KB) | References Amy L Oldenburg^1,2 and Stephen A Boppart^1,3,4 ^1 Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Ch... (Read Full Article)
   

   Comment on Article Mentions:   University of Illinois at Urbana-Champaign   Stephen A. Boppart   Amy L. Oldenburg

4. Three Dimensional OCT in the Engineering of Tissue Constructs: A Potentially Powerful Tool for Assessing Optimal Scaffold Structure

   Explore Article Comcast.net (Jan 9 2010)

   ... imaging modality in tissue engineering. Phys Med Biol 2006; 51(7): 1649-59. Ko HJ, Tan W, Stack R, Boppart SA. Optical coherence elastography of engineered and developing tissue. Tissue Eng 2006; 12(1): 63-73.... (Read Full Article)
   

   Comment on Article Mentions:   Brigham and Women’s Hospital   Mark E. Brezinski   Harvard University

5. Partially coherent illumination for inverse scattering full-field interferometric synthetic aperture microscopy

   Explore Article PatFT » Page 1 of 1 (Jan 4 2010) Microscopy , Patents

   Methods and apparatus for three-dimensional imaging of a sample. A source is provided of a beam of light characterized by partial spatial coherence. The beam is focused onto a sample and scattered light from the sample is superposed with a reference beam derived from the source onto a focal plane detector array to provide an interference signal. A forward scattering model is derived relating measurement data to structure of an ... (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Daniel L. Marks

6. Optics may speed breast cancer diagnosis

   Explore Article Futurity.org (Dec 10 2009) Oncology

   ...l-time information on breast cancer tissue margins while still in the operating room. Developed by Stephen Boppart, professor of electrical and computer engineering, bioengineering, and medicine, at the University ......echnology for imaging subsurface biological tissue—to provide high-resolution, micron-scale images. Boppart put his system to the test through a collaborative study involving his laboratory at Illinois’s Bec... (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

7. Imaging and Analysis of Three-Dimensional Cell Culture Models

   Explore Article SpringerLink Home (Dec 4 2009)

   Three-dimensional (3D) cell cultures are important tools in cell biology research and tissue engineering because they more closely resemble the architectural microenvironment of natural tissue, compared to standard two-dimensional cultures. Microscopy techniques that function well for thin, optically transparent cultures, however, are poorly suited for imaging 3D cell cultures. Three-dimensional cultures may be thick and highly scattering, preventing light from penetrating without significant distortion. Techniques that can image thicker biological ... (Read Full Article)
   

   Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

8. Magnetomotive nanoparticle transducers for optical rheology of viscoelastic materials

   Explore Article opticsinfobase.org (Dec 2 2009)

   ...logy of viscoelastic materials Vasilica Crecea, Amy L. Oldenburg, Xing Liang, Tyler S. Ralston, and Stephen A. Boppart Optics Express, Vol. 17, Issue 25, pp. 23114-23122 doi:10.1364/OE.17.023114 » V... (Read Full Article)
   

   Comment on Article Mentions:   Xing Liang   Tyler S. Ralston   Amy L. Oldenburg

9. Dynamic optical coherence elastography and applications

   Explore Article SPIE Digital Library (Nov 25 2009)

   ...nce Chairs: Xingde Li, Qingming Luo, Vasilis Ntziachristos, Yoshiaki Yasuno ABSTRACT Xing Liang and Stephen A. Boppart Univ. of Illinois at Urbana-Champaign (USA) Dynamic^ optical coherence elastography, an emerging op... (Read Full Article)
   

   Comment on Article Mentions:   Xing Liang   Stephen A. Boppart   University of Illinois at Urbana-Champaign

10. Nonlinear interferometric vibrational imaging

    Explore Article PatFT » Page 1 of 1 (Nov 24 2009) Patents

    ...ical Coherence Tomography. Science 254:1178-1181, 1991.2. Fujimoto J G, Brezinski M E, Tearney G J, Boppart S A, Bouma B E, Hee M R, Southern J F, Swanson E A. Biomedical imaging and optical biopsy using opt... (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Daniel L. Marks

11. Optical Coherence Tomography Identifies Surgical Margins for Breast Cancer Intraoperatively

    Explore Article docguide.com (Nov 18 2009) Oncology

    ...in real time, at the point of care, rather than relying on postoperative histopathology," said Stephen Boppart, MD, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana, Champ...... for Advanced Science and Technology, University of Illinois at Urbana, Champaign, Illinois. Dr. Boppart and colleagues demonstrated the feasibility of using this technology for evaluating surgical margin... (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign

12. Intraoperative Evaluation of Breast Tumor Margins with Optical Coherence Tomography

    Explore Article Cancer Research (Nov 12 2009) Oncology

    ... Carle Foundation Hospital, and 7 Carle Clinic Association, Urbana, Illinois Requests for reprints: Stephen A. Boppart, University of Illinois at Urbana-Champaign, 405 North Mathews Avenue, Urbana, IL 61801. Phone: 217... (Read Full Article)
    

    Comment on Article Mentions:   University of Illinois at Urbana-Champaign   Stephen A. Boppart   Eric J. Chaney

13. Multi-functional plasmon-resonant contrast agents for optical coherence tomography

    Explore Article PatFT » Page 1 of 1 (Oct 27 2009) Patents

    ...ptical Coherence Tomography. Science 254:1178-81, 1991.6. Fujimoto J G, Brezinski M E, Tearney G J, Boppart S A, Bouma B E, Hee M R, Southern J F, Swanson E A. Biomedical imaging and optical biopsy using opt... (Read Full Article)
    

    Comment on Article Mentions:   Alexander Wei   Stephen A. Boppart   University of Illinois at Urbana-Champaign

14. Interferometric synthetic aperture microscopy

    Explore Article PatFT » Page 1 of 1 (Oct 13 2009) Microscopy , Patents

    Methods and apparatus for three-dimensional imaging of a sample. A source is provided of a beam of substantially collimated light characterized by a temporally dependent spectrum. The beam is focused in a plane characterized by a fixed displacement along the propagation axis of the beam, and scattered light from the sample is superposed with a reference beam derived from the substantially collimated source onto a focal plane detector array to ... (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Tyler S. Ralston

15. Biomechanical Properties of in Vivo Human Skin From Dynamic Optical Coherence Elastography

    Explore Article IEEE Xplore (Oct 9 2009) Dermatology

    Dynamic optical coherence elastography is used to determine in vivoskin biomechanical properties based on mechanical surface wave propagation. Quantitative Youngs moduli are measured on human skin from different sites, orientations, and frequencies. Skin thickness, including measurements from different layers, are also measured simultaneously. Experimental results show significant differences among measurements from different skin sites, between directions parallel and orthogonal to Langers lines, and under different skin hydration states. Results also ... (Read Full Article)
    

    Comment on Article Mentions:   Stephen A. Boppart   University of Illinois at Urbana-Champaign   Xing Liang

16. Optical Coherence Tomography for Cancer Detection

    Explore Article SpringerLink Home (Oct 3 2009) Oncology , Probes

    Optical coherence tomography (OCT) is an emerging high-resolution medical and biological imaging technology that is currently making the transition from the research lab into clinical practice. OCT is analogous to ultrasound B-mode imaging except that reflections of light are detected rather than sound. This technique is attractive for medical imaging because it permits real-time in situ imaging of tissue microstructure with resolution approaching that of conventional histology, but without the ... (Read Full Article)
    

    Comment on Article Mentions:   University of Illinois at Urbana-Champaign   Stephen A. Boppart   Steven G. Adie

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