Bioptigen

About Bioptigen

Bioptigen.  Ophthalmology and General Research Systems.  Bioptigen has pioneered a new class of in vivo optical imaging systems for biomedical applications. These systems enable real-time non-invasive imaging of internal tissue microstructure, advancing critical applications in drug development, genetics research, tissue engineering, and medical vision.  Bioptigen is a spin-out of the Duke University Biomedical Engineering Department. Bioptigen was incorporated in North Carolina in August, 2004, to commercialize technologies originating in the laboratories of Professor Joseph Izatt. Bioptigen technology is based on the science of Optical Coherence Tomography (OCT), an imaging system similar in function to ultrasound, but using low-power light rather than sound waves. OCT offers resolution 100-times finer than standard ultrasound, suitable for analyzing tissue microstructure with features smaller than 10 micrometer.

Quotes about Bioptigen

1. “ Bioptigen allows you to sum up multiple images of a particular cut. ”

   In New Technology: Bioptigen SDOCT Boosts Flexibility

2. “ Bioptigen is very pleased to extend its relationship with Case through this new technology agreement.  The intellectual property licensed by Case is fundamental to our ability to provide the highest performance FDOCT imaging system today and to develop new clinical tools that will dramatically extend the clinical value of FDOCT into the future. ”

   Eric L. Buckland in Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement

3. “ We look forward to working with Bioptigen to incorporate the Case technology and expand their product portfolio to address medical disciplines beyond ocular imaging. ”

   In Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement

1. Mentioned In 50 Articles

2. Gene Deletion Screen for Cardiomyopathy in Adult Drosophila Identifies a New Notch Ligand

   Explore Article Circulation Research (Mar 7 2010) Cardiology , Developmental Biology

   Rationale: Drosophila has been recognized as a model to study human cardiac diseases. Objective: Despite these findings, and the wealth of tools that are available to the fly community, forward genetic screens for adult heart phenotypes have been rarely performed because of the difficulty in accurately measuring cardiac function in adult Drosophila. Methods and Results: Using optical coherence tomography to obtain real-time analysis of cardiac function in awake Drosophila, we ... (Read Full Article)
   

   Comment on Article Mentions:   Duke University   Bioptigen

3. Revealing the Body's Deepest Secrets

   Explore Article parade.com (Feb 19 2010)

   For more than a century, X-rays have allowed doctors to observe the inner workings of the human body. Today a new generation of imaging devices is probing even deeper—and transforming medicine in the process. Take the case of a 53-year-old woman rushed to the emergency room of Suburban Hospital in Bethesda, Md., with chest pains. Heart attack or just indigestion? It’s a common dilemma. Every minute counts when treating heart ... (Read Full Article)
   

   Comment on Article Mentions:   Rice University   National Institutes of Health   Yale University

4. Unusual Adaptive Optics Findings in a Patient With Bilateral Maculopathy

   Explore Article Archives of Ophthalmology (Feb 8 2010) Ophthalmology

   Over the past decade there has been a rapid evolution in our ability to noninvasively image the living human retina. Of particular interest is adaptive optics (AO), a technique that corrects for the eye's monochromatic aberrations and allows nearly diffraction-limited imaging of the retina.1 There is increasing clinical application of AO imaging2-5 owing to the ability to resolve retinal pathological changes on a cellular level, although the future of AO ... (Read Full Article)
   

   Comment on Article Mentions:   University of Wisconsin   Heidelberg Engineering   Bioptigen

5. Spectral-Domain Optical Coherence Tomography and Adaptive Optics May Detect Hydroxychloroquine Retinal Toxicity Before Symptomatic Vision Loss

   Explore Article aosonline.org (Feb 4 2010) Ophthalmology

   ...al architecture was preserved in both patients. FIGURE 1 Patient 1. Fluorescein angiogram (FA) and Bioptigen SD-OCT images of left eye. SD-OCT images are registered onto FA fundus photo. Upper SD-OCT image is... (Read Full Article)
   

   Comment on Article Mentions:   University of Wisconsin   Bioptigen

6. Big Ideas from Small Businesses: Vision-related research by innovative thinkers - Imaging the eyes of infants

   Explore Article nei.nih.gov (Feb 2 2010) Ophthalmology , Other Business News

   ...research community was asking for these tools," he explains. Buckland and Izatt co-founded Bioptigen, Inc. in 2004. They used NEI SBIR funding to develop a versatile OCT system that includes interchan... (Read Full Article)
   

   Comment on Article Mentions:   Eric L. Buckland   Bioptigen   Joseph A. Izatt

7. Optical Coherence Tomography (OCT) Imaging Systems For Use In Pediatric Ophthalmic Applications And Related Methods And Computer Program Products (Wo 2009/131679)

   Explore Article wipo.int (Oct 29 2009) Ophthalmology , Patents

   Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path ... (Read Full Article)
   

   Comment on Article Mentions:   Joseph A. Izatt   Eric L. Buckland   Bioptigen

8. Optical Coherence Tomography (OCT) Imaging Systems Having Adaptable Lens Systems And Related Methods And Computer Program Products (Wo 2009/131701)

   Explore Article wipo.int (Oct 29 2009) Ophthalmology , Patents

   OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal ... (Read Full Article)
   

   Comment on Article Mentions:   Joseph A. Izatt   Eric L. Buckland   Bioptigen

9. Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement

   Explore Article Optical Coherence Tomography News (Oct 24 2009) Other Business News , Patents

   Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement Technology Helps Doctors and Researchers Diagnose and See... (Read Full Article)
   

   Comment on Article Mentions:   Joseph A. Izatt   Andrew M. Rollins   Duke University

10. Optical coherence imaging systems having a reduced effective linewidth and methods of using the same

    Explore Article PatFT » Page 1 of 1 (Oct 13 2009) Patents

    Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter. (Read Full Article)
    

    Comment on Article Mentions:   Joseph A. Izatt   Eric L. Buckland   Bioptigen

11. Handheld device detects blindness in infants

    Explore Article Technology News (Sep 30 2009) Ophthalmology

    ...to determine what role the imaging could play in treatment decisions: The device is manufactured by Bioptigen, a Duke spinout company for whom Izatt is the chairman and chief technology officer. Research was s... (Read Full Article)
    

    Comment on Article Mentions:   Duke University   Cynthia A. Toth   Bioptigen

12. Serial Examination of an Inducible and Reversible Dilated Cardiomyopathy in Individual Adult Drosophila

    Explore Article PLoS ONE (Sep 24 2009) Developmental Biology

    ...ures. Cardiac function in adult Drosophila was measured using a custom built OCT microscopy system (Bioptigen, Inc) as previously described.[4] Briefly, adult Drosophila at 7 days post eclosion were briefly su... (Read Full Article)
    

    Comment on Article Mentions:   Duke University   Bioptigen

13. New device finds early signs of eye disease in preemies

    Explore Article PhysOrg.com (Sep 21 2009) Ophthalmology

    ...T system can be taken directly to premature infants in the incubator. The device is manufactured by Bioptigen, Inc., a Duke spinout company in Research Triangle Park. Izatt is the chairman and chief technology... (Read Full Article)
    

    Comment on Article Mentions:   Duke University   Bioptigen   National Eye Institute

14. Insights into Advanced Retinopathy of Prematurity Using Handheld Spectral Domain Optical Coherence Tomography Imaging

    Explore Article OphSource (Sep 17 2009) Ophthalmology

    ... disclosure(s): Dr. Toth receives research support through Duke University from Alcon Laboratories, Bioptigen, Genentech, National Institutes of Health, North Carolina Biotechnology Center, and Sirion; is a ... (Read Full Article)
    

    Comment on Article Mentions:   Duke University   Cynthia A. Toth   Bioptigen

15. CED’s September STREAK Seminar To Feature Research Triangle Park-Based Bioptigen

    Explore Article Free Press Release Distribution (Sep 8 2009) Other Business News

    ...www.cednc.org www.bcentral.com Quotes: “We are excited to provide the benefits offered by STREAK to Bioptigen,” said Rose. “This program connects our region’s most promising startup companies with a number of... (Read Full Article)
    

    Comment on Article Mentions:   Eric L. Buckland   Bioptigen

16. Spectral domain phase microscopy (sdpm) dual mode imaging systems and related methods and computer program products

    Explore Article PatFT » Page 1 of 1 (Jun 30 2009) Patents

    Some embodiments of the present invention provide optical coherence tomography systems including an OCT engine and a processor. The OCT engine is configured to provide both standard OCT imaging and spectral domain phase microscopy (SDPM) imaging. The processor is coupled to the OCT engine and is configured to use a first signal processing method when the OCT engine is configured to provide standard OCT imaging and a second signal processing ... (Read Full Article)
    

    Comment on Article Mentions:   Joseph A. Izatt   Eric L. Buckland   Bioptigen

1-15 of 50 // 1 2 3 4 »