1. Articles in category: Gastroenterology

    505-528 of 542 « 1 2 ... 19 20 21 22 23 »
    1. Optical Technique Provides Improved 'Virtual Biopsies' Of Internal Surfaces

      Optical Technique Provides Improved 'Virtual Biopsies' Of Internal Surfaces
      A new optical imaging technique, developed at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH), can provide three-dimensional microscopic views of the inner surfaces of blood vessels and gastrointestinal organs. In their report in the journal Nature Medicine, receiving early online release today, the MGH-Wellman researchers describe using optical frequency-domain imaging (OFDI) to visualize broad areas of the esophagus and coronary arteries of living pigs. The technique is an advance over optical coherence tomography (OCT) -- another noninvasive MGH-developed technology that details much smaller areas -- and could be useful for identifying precancerous lesions and dangerous deposits of plaque in ...
      Read Full Article
    2. Robotic endoscope with wireless interface

      An endoscope apparatus and method of operating the same. The endoscope apparatus comprises an endoscope portion and a control and display unit. The endoscope portion preferably comprises: (i) a sensor disposed at a distal end of the endoscope portion and providing endoscope data; (ii) one or more electronically controlled actuators (e.g., electroactive polymer actuators) controlling the operation of the endoscope portion based on received control signals; (iii) a first wireless transceiver coupled to the sensor and the one or more electronically controlled actuators, transmitting received endoscope data from the sensor and forwarding received control signals to the one or ...
      Read Full Article
    3. Endoscopic optical coherence tomography and laser-induced fluorescence spectroscopy in a murine colon cancer model

      Background and Objectives The diagnostic feasibility of optical coherence tomography (OCT) and laser-induced fluorescence (LIF) have been evaluated for human colorectal cancer. This study applies these technologies to a murine model of colorectal adenoma. Study Design/Materials and Methods The lower colon of 10 ApcMin and two C57BL/6J mice was surveyed over five 4-week intervals using a prototype 2.0 mm diameter OCT-LIF endoscope-based system. Four categories were histologically classified: control C57BL/6J, adenomatous, non-diseased regions of adenomatous, and non-diseased ApcMin. OCT images were compared to histology. Spectra from the four categories were compared via the Student's t-test ...

      Read Full Article
    4. Anatomical optical coherence tomography in the human upper airway (Thesis)

      Anatomical optical coherence tomography in the human upper airway (Thesis)
      This thesis describes the development, clinical validation and initial application of a technique for taking measurements of the shape and dimensions of the human upper airway, called anatomical optical coherence tomography (aOCT). The technique uses a transparent catheter containing a rotating optical probe which is introduced transnasally and positioned in the airway and oesophagus. Optical coherence tomography is used to take calibrated cross-sectional images of the airway lumen as the probe rotates. The probe can also be advanced or withdrawn within the catheter during scanning to build up three-dimensional information. The catheter remains stationary so that the subject is not ...
      Read Full Article
    5. Imaging apparatus

      An compact imaging apparatus having an OCT function is provided. An image formed of the illuminating-light reflected from a examination area is displayed on a monitor. A signal-light for obtaining an optical tomographic image is guided in a fiber through an insertion portion and projected onto a living tissue measurement area by an illuminating lens. The measurement area is scanned with the signal-light by a Piezo actuator moving the output face of the fiber. An OCT obtaining-portion obtains and displays on a monitor an optical tomographic image by using the interference caused by the signal-light reflected from the measurement area ...
      Read Full Article
    6. Optical Coherence Tomography to Identify Intramucosal Carcinoma and High-Grade Dysplasia in Barrett’s Esophagus

      Optical Coherence Tomography to Identify Intramucosal Carcinoma and High-Grade Dysplasia in Barrett’s Esophagus
      Background & Aims: Optical coherence tomography (OCT) is an optical technique that produces high-resolution images of the esophagus during endoscopy. OCT can distinguish specialized intestinal metaplasia (SIM) from squamous mucosa, but image criteria for differentiating intramucosal carcinoma (IMC) and high-grade dysplasia (HGD) from low-grade dysplasia (LGD), indeterminate-grade dysplasia (IGD), and SIM without dysplasia have not been validated. The purpose of this study was to establish OCT image characteristics of IMC and HGD in Barrett’s esophagus. Methods: Biopsy-correlated OCT images were acquired from patients with Barrett’s esophagus undergoing endoscopic surveillance. Two pathologists rendered consensus diagnoses of the biopsy specimens. A ...
      Read Full Article
    7. Accuracy of endoscopic optical coherence tomography in the detection of dysplasia in Barrett's esophagus: a prospective, double-blinded study

      Accuracy of endoscopic optical coherence tomography in the detection of dysplasia in Barrett's esophagus: a prospective, double-blinded study

      Background Endoscopic optical coherence tomography (EOCT) is a high-resolution, cross-sectional tissue-imaging technique that provides microscopic morphologic information. EOCT should detect dysplasia in Barrett's epithelium, but this has not been established in a prospective blinded study. This study evaluated the accuracy of EOCT for the diagnosis and the exclusion of dysplasia in patients with Barrett's esophagus. Methods A 2.4-mm diameter EOCT probe was modified for use with a cap-fitted, two-channel endoscope. Pairs of EOCT image streams and jumbo biopsy specimens were obtained. Endoscopy/EOCT procedures were performed by 4 endoscopists who separately reviewed the EOCT digital images for ...

      Read Full Article
    8. Methods for forming an optical window for an intracorporeal device and for joining parts

      Optical windows for intracorporeal devices, intracorporeal devices comprising a window and a method for forming a window for an intracorporeal device are provided. The method comprises placing within a mold an assembly comprising a mandrel located within a pair of parts separated by a collar of window material, heating the window preform effective to cause the window material to soften, and applying force to urge together the pair of parts to deform the window material so as to form a window. The intracorporeal devices, such as imaging devices, include guidewires, catheters, endoscopes. In addition, the method is suitable for joining ...
      Read Full Article
    9. Medical scanning system and related method of scanning

      The present invention is directed to a scanning system that uses uniform rotary motion of an optical reflector to create reciprocal linear scanning. The system converts uniform rotation into uniform longitudinal scanning. The system thereby creates mechanical reciprocal linear scanning free of reciprocally moving mechanical parts common in conventional scanning systems. In a preferred embodiment of the invention, the scanning system is incorporated within an imaging catheter for medical scanning. The optical reflector is rotatable and includes a spiral reflecting portion. The spiral reflecting portion may be a single uniform reflecting surface or may include several reflection surfaces arranged in ...
      Read Full Article
    10. Optical Coherence Tomography of the Gastrointestinal Tract (OCT)

      Optical coherence tomography (OCT) is a non-invasive imaging technique that uses light to create pictures of living tissues and has been successfully used to generate high resolution cross-sectional images of tissue in the human eye and skin. OCT systems are now commercially available for eye and skin use, and several clinical reports on the use of OCT in the gastrointestinal tract have been published as well. The purpose of this study is to develop a high-speed noninvasive OCT probe which can be placed through an endoscope for the early diagnosis of pre-cancerous and cancerous lesions in the gastrointestinal tract. This ...
      Read Full Article
    11. Endoscope system

      An endoscope system is provided with a light guide including a plurality of optical paths, and a low-coherent light source that emits a low-coherent light beams. The low-coherent light source is provided at a proximal end side of the light guide. The light beams emitted by the low-coherent light source are incident on the plurality of optical paths, respectively. The endoscope system is further provided with an interferometer unit. The interferometer unit includes a beam splitting element that splits each of the low-coherent beams emitted from the distal end of the light guide and emits split one of each of ...
      Read Full Article
      Mentions: Pentax
    12. Endoscope system, scanning optical system and polygon mirror

      An endoscope system which can obtain a tomographic image in accordance with optical coherence tomography (OCT). An OCT section of the endoscope system comprises a first optical fiber, a second optical fiber, an optical coupler, a super-luminescent diode (SLD), a photodetector, and a reference mirror. The first optical fiber is opposed to the SLD at its proximal end. The second optical fiber is opposed to the photodetector at its proximal end. The optical coupler establishes optical connection between the optical fibers. The reference mirror is arranged movable in front of the distal end of the second optical fiber. The distal ...
      Read Full Article
      Mentions: Pentax
    13. Miniature Endoscope for Simultaneous Optical Coherence Tomography and Laser-Induced Fluorescence Measurement

      We have designed a multimodality system that combines optical coherence tomography (OCT) and laser-induced fluorescence (LIF) in a 2.0-mm-diameter endoscopic package. OCT provides ~18-μm resolution cross-sectional structural information over a 6-mm field. LIF spectra are collected sequentially at submillimeter resolution across the same field and provide histochemical information about the tissue. We present the use of a rod prism to reduce the asymmetry in the OCT beam caused by a cylindrical window. The endoscope has been applied to investigate mouse colon cancer in vivo.
      Read Full Article
    14. Endoscope apparatus for setting a scanning area

      An endoscope apparatus that has an OCT function and can efficiently obtain an optical tomographic image is provided. An image of an area within a body cavity is displayed on a monitor, and an operator uses a pen-type input to specify a point thereon. An aiming-light is projected onto the body cavity and displayed on said monitor as a bright point, and a coated tube of an OCT probe is slid and rotated by a scanning controller so as to align the aiming-light with the point. A scanning-area setting means sets a ring shaped scanning area when the aiming-light and ...
      Read Full Article
    15. Method and apparatus for obtaining an optical tomographic image of a sentinel lymph node

      An apparatus for obtaining a cellular image to be used in performing a test for pathology of the sentinel lymph node, which is the first lymph node a cancer metastasizes to. The gamma radiation emitted from a near-infrared fluorescent colorant injected in advance into the vicinity of a tumor is detected by use of a gamma-probe. A fiber coupler separates the low-coherence light emitted from the light source of an OCT portion (Optical Coherence Tomography) into a signal-light to be projected onto the sentinel lymph node and a reference-light whose wavelength is slightly shifted. The signal-light is projected onto the ...
      Read Full Article
    16. Optical imaging device

      An Optical Coherence Tomography (OCT) device irradiates a biological tissue with low coherence light, obtains a high resolution tomogram of the inside of the tissue by low-coherent interference with scattered light from the tissue, and is provided with an optical probe which includes an optical fiber having a flexible and thin insertion part for introducing the low coherent light. When the optical probe is inserted into a blood vessel or a patient's body cavity, the OCT enables the doctor to observe a high resolution tomogram. In a optical probe, generally, a fluctuation of a birefringence occurs depending on a ...
      Read Full Article
    17. Optical coherent tomography apparatus, fiberoptic lateral scanner and method for studying biological tissues in vivo

      The present invention relates to the analysis of the internal structures of objects using optical means. According to the invention there were designed an apparatus suited for optical coherence tomography (OCT), an optical fiber lateral scanner (15), which is a part of said apparatus and is incorporated into an optical fiber probe (8), and a method for studying biological tissue in vivo, which allows for making a diagnostics of the biological tissue under, study on basis of the state of the basal membrane (46). The moving part of lateral scanner (15) of sampling arm (4) of interferometer (2) is arranged ...
      Read Full Article
    18. Fiber bundle and endoscope apparatus

      A fiber bundle for image transmission includes pluralities of first optical fibers and a plurality of second optical fibers. Both pluralities of optical fibers being tied at their distal ends to form a composite bundle portion. The first optical fibers being tied at their proximal ends to form a first branched bundle portion and the second optical fibers being tied at their proximal ends to form a second branched bundle portion.
      Read Full Article
      Mentions: Pentax
    19. Apparatus for in vivo imaging of the respiratory tract and other internal organs

      Apparatus for acquiring in vivo images of a site of interest within the internal organs of a body. The apparatus includes an elongate, flexible catheter. The catheter is introducible into the body and has a first end that remains external to the body and a second and positionable adjacent the site of interest. A movable scanning unit having at least one sensor for acquiring images is housed adjacent the second end of the catheter. There is a drive mechanism to control movement of the movable scanning unit from the first external end of the catheter to acquire multiple images of ...
      Read Full Article
    20. Endoscope System

      An endoscope system capable of obtaining a normal light image and/or fluorescent light image is further provided with an a low-coherent light source arranged on a proximal end side of one of first and second light guides. A scanning unit is provided to cause the low-coherent light beam emerged from a tip of the first light guide to scan on the object. The low-coherent light reflected by the object is directed to the first light guide by the scanning unit as detecting light. A mirror is provided to reflect the low-coherent light beam emerged from a tip of the ...
      Read Full Article
      Mentions: Pentax
    505-528 of 542 « 1 2 ... 19 20 21 22 23 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (1 articles) Harvard University
    2. (1 articles) Nanyang Technological University
    3. (1 articles) Massachusetts Institute of Technology
  4. People in the News

    1. (1 articles) Tsung-Han Tsai
    2. (1 articles) Vijay Jayaraman
    3. (1 articles) James G. Fujimoto
    4. (1 articles) Zhao Wang
    5. (1 articles) Hsiang-Chieh Lee
    6. (1 articles) Hiroshi Mashimo
    7. (1 articles) Osman O. Ahsen
    8. (1 articles) Linbo Liu
    9. (1 articles) Benjamin M. Potsaid
    10. (1 articles) Xingde Li
  5. OCT Companies in the News

    1. (1 articles) Thorlabs
    2. (1 articles) Praevium Research