1. Articles in category: Textbooks

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    1. Essentials of OCT in Ocular Disease (Textbook)

      Essentials of OCT in Ocular Disease (Textbook)

      Written by the leading authorities in the field, Essentials of OCT in Ocular Disease is a core clinical reference on this important new technology used to examine the structure of the eye. It provides residents and practicing ophthalmologists with essential information on how to use OCT in various clinical scenarios and guidance on patient management. Chapters include coverage of recent innovative diagnostic applications as well as OCT-guided surgical procedures,including IOL position, DMEK, PDEK, GLUED IOL, and subtenon injection. Key Features: Edited by Amar Agarwal, a pioneer in OCT research, with chapters written by world-renowned experts in the use of ...

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    2. OCT in Central Nervous System Disease: The Eye as a Window to the Brain (Textbook)

      OCT in Central Nervous System Disease: The Eye as a Window to the Brain (Textbook)

      This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment ...

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    3. Optical Coherence Tomography in Neurologic Disease (Textbook)

      Optical Coherence Tomography in Neurologic Disease (Textbook)

      Shortly after the invention of the first two-dimensional optical coherence tomography (OCT) scans by James Fujimoto and colleagues at the Massachusetts Institute of Technology in 1991, ophthalmologists recognized the extraordinary potential for OCT to facilitate quantitative assessment of the neuroretina. OCT rapidly became a commonplace tool in ophthalmologic practice to identify both inflammatory and degenerative conditions affecting the optic nerve and retina. The utility of OCT to detect and quantify sequelae of optic neuropathies, including glaucoma and those associated with primary neurological diseases , was soon brought to the forefront. Rapid advances in the technology have followed and have included faster ...

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    4. OCT Angiography in Retinal and Macular Diseases (Textbook)

      OCT Angiography in Retinal and Macular Diseases (Textbook)

      In only a short period of time, the innovative procedure of OCT angiography has become an essential macula imaging technique. Now that it is routinely used in clinical practice, the investigation of retinal and choroidal circulation is noninvasive, which significantly changes the professional’s approach to patients. In this volume, retina specialists and renowned experts share their experience with OCT angiography. They have included numerous color images and presented current ideas to form a base for further research and discussion. This book provides retina specialists, ophthalmologists, and researchers with a first glance at original research and clinical reports on this ...

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    5. Optical Coherence Tomography in Grafts (Book Chapter)

      Optical Coherence Tomography in Grafts (Book Chapter)

      Coronary artery bypass graft (CABG) is a commonly used surgery to treat patients with complex artery disease. Long-term outcome of specifically saphenous vein grafts (SVG) is considered unfavorable, while it is the most commonly used conduit. The SVG is prone to occlude and half of the patients will develop vein graft failure (VGF) within 10 years. VGF is the result of the accelerated atherosclerosis that differs from what is seen in native coronaries. Revascularization of SVGs is considered challenging, due to their challenging anatomy and embolic nature. Optical coherence tomography (OCT) imaging is an invasive imaging technique that can be ...

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    6. Optical Coherence Tomography and OCT Angiography (Textbook)

      Optical Coherence Tomography and OCT Angiography (Textbook)

      OCT angiography (OCTA) is a revolutionary imaging modality that allows visualization of the vascular flow in the retina and choroid en vivo. Optical Coherence Tomography and OCT Angiography is a comprehensive guide that explains the science of OCT and OCT angiography, as well as clinical interpretation of images. As OCT angiography becomes the clinical standard, it is imperative to develop the nomenclature and descriptive interpretation to guide diagnosis and treatment. This book is intended for use by clinicians, technicians and imagers to develop a standard vocabulary and help guide the user towards more accurate assessment, and promises to be the ...

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    7. Optical Coherence Tomography (Book Chapter)

      Optical Coherence Tomography (Book Chapter)

      The evaluation of the optical coherence tomography (OCT) is based on the identification of differences in the relative reflectivity of different tissue layers and morphological changes in tissue structures. So the examination is able to localize and grossly demarcate inflammation in the vitreous cavity (by its dynamic analysis) or beneath retinal layers as well as detail retinal changes on the chronic phases of retinal disease like fibrosis, atrophy, or retinal edema.

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    8. Optical Coherence Tomography of Vascular Disorders, Malformations, and Tumors (Textbook)

      Optical Coherence Tomography of Vascular Disorders, Malformations, and Tumors (Textbook)

      Equips the reader to identify anatomy and ophthalmic disease as illustrated on optical coherence tomography (OCT) Includes numerous high-quality images, ensuring that key points can be easily followed. This richly illustrated, comprehensive guide will enable the reader to identify anatomy and ophthalmic disease as illustrated on optical coherence tomography (OCT). It is the most up-to-date atlas of OCT images, many of which have been obtained with the newer OCT technologies that offer excellent image quality and definition at a microscopic level. All of the major disease areas in ophthalmology are covered, including diabetic retinopathy, age-related macular degeneration, uveitis, glaucoma, retinal ...

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    9. Optical Coherence Tomography for Assessment of Percutaneous Coronary Intervention with Excimer Laser Coronary Atherectomy (Book Chapter)

      Optical Coherence Tomography for Assessment of Percutaneous Coronary Intervention with Excimer Laser Coronary Atherectomy (Book Chapter)

      The indications for Excimer laser coronary atherectomy (ELCA) have been refined in modern interventional practice. With the expanding role for optical coherence tomography (OCT) providing high-resolution intra-coronary imaging, this article examines the appearance of the coronary lumen after ELCA. Each indication for ELCA is discussed and illustrated with a clinical case, followed by detailed analysis of the OCT imaging pre and post ELCA. The aim of the article is to provide information to interventional cardiologists to facilitate decision making during PCI, when ELCA has been used as part of the interventional strategy.

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    10. Optical coherence tomography in current glaucoma practice: pearls and pitfalls (Textbook)

      Optical coherence tomography in current glaucoma practice: pearls and pitfalls (Textbook)

      Glaucoma is a condition of the eye in which the optic nerve is damaged due to increased fluid pressure in the eye. Left untreated, the condition may lead to permanent blindness. Optical coherence tomography (OCT) is a non-invasive imaging test that uses light waves to take cross-section pictures of the retina, the light-sensitive tissue lining the back of the eye (geteyesmart.org). OCT is commonly used in the evaluation of patients with glaucoma. This manual is a concise guide to the use of OCT for the diagnosis of glaucoma. Beginning with an introduction to OCT, the book then provides in ...

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    11. Diagnostic Optical Imaging Technology and Its Principles (Book Chapter)

      Diagnostic Optical Imaging Technology and Its Principles (Book Chapter)

      Analysis of tissue structures is important for investigating pathological changes and diagnosing neural diseases. Recent advances in ophthalmology regarding the diagnosis of neurosensory retinal diseases have introduced optical coherence tomography (OCT) as a near-infrared imaging modality to provide noninvasive and real-time imaging and sensing with ultrahigh resolution for imaging subsurface cross sections of the human retina. This chapter gives a brief overview and the basic principles of this emerging optical imaging modality.

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      Mentions: Korea University
    12. Interpretation of Flood-Illuminated Adaptive Optics Images in Subjects with Retinitis Pigmentosa (Book Chapter)

      Interpretation of Flood-Illuminated Adaptive Optics Images in Subjects with Retinitis Pigmentosa (Book Chapter)

      The purpose of this study was to correlate features on flood-illuminated adaptive optics (AO) images with color fundus, fundus autofluorescence (FAF) and spectral domain optical coherence tomography (SD-OCT) images in patients with retinitis pigmentosa (RP). We imaged 39 subjects diagnosed with RP using the rtx1 TM flood-illuminated AO camera from Imagine Eyes (Orsay, France). We observed a correlation between hyper-autofluoresence changes on FAF, disruption of the interdigitation zone (IZ) on SD-OCT and loss of reflective cone profiles on AO. Four main patterns of cone-reflectivity were seen on AO: presumed healthy cone mosaics, hypo-reflective blurred cone-like structures, higher frequency disorganized hyper-reflective ...

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    13. Optical Coherence Tomography in Multiple Sclerosis: Clinical Applications (Textbook)

      Optical Coherence Tomography in Multiple Sclerosis: Clinical Applications (Textbook)

      This book gives a clinical context to optical coherence tomography (OCT) findings, while considering the differential diagnosis and providing patient management guidance. Relevant anatomical and technical aspects are discussed, followed by a pragmatic illustration of the use of OCT for the clinical spectrum of multiple sclerosis and optic neuritis, and finishing with information on monitoring ocular side effects of recently approved disease-modifying treatments in multiple sclerosis. Optical Coherence Tomography in Multiple Sclerosis: Clinical Applications is aimed at clinical neurologists working with patients suffering from MS and general neurologists who see patients with visual symptoms in their daily practice. Ophthalmologists sharing ...

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    14. Beyond Endoscopy-Ultrasound, Optical Coherence Tomography and Confocal Laser Endomicroscopy (Book Chapter)

      Beyond Endoscopy-Ultrasound, Optical Coherence Tomography and Confocal Laser Endomicroscopy (Book Chapter)

      One of the main challenges in endoscopic diagnosis and treatment of upper urinary tract urothelial carcinoma is the complicated anatomy and the small size of the upper urinary tract, resulting in high demands on the armamentarium and expertise of the urologist. Difficulties to reach the complete collecting system could result in an incomplete visual inspection.

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    15. Smart Sensors for Health and Environment Monitoring (Book)

      Smart Sensors for Health and Environment Monitoring (Book)

      This book covers two most important applications of smart sensors, namely bio-health sensing and environmental monitoring. The approach taken is holistic and covers the complete scope of the subject matter from the principles of the sensing mechanism, through device physics, circuit and system implementation techniques, and energy issues to wireless connectivity solutions. It is written at a level suitable mainly for post-graduate level researchers interested in practical applications. The chapters are independent but complementary to each other, and the book works within the wider perspective of essential smart sensors for the Internet of Things (IoT). This is the second of ...

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    16. The Role of Multiple Imaging Modalities to Disclose the Mechanism of ACS Angioscopy in Comparison to Other Imaging Modalities Including OCT, IVUS and CTA (Book Chapter)

      The Role of Multiple Imaging Modalities to Disclose the Mechanism of ACS Angioscopy in Comparison to Other Imaging Modalities Including OCT, IVUS and CTA (Book Chapter)

      This book presents a thorough review of coronary angioscopy, ranging from instructions on its use to the latest advances. Starting with the structure and fundamental principles of angioscopy, it shows readers how to apply the image to comprehensive care of coronary-artery patients. Plentiful color photos and illustrations will enable readers to investigate and classify plaques and thrombi and to evaluate coronary stent- and drug-based therapies. The authors are leading researchers on angioscopy. This book offers the perfect guide not only for new clinicians but also for cardiologists who have already adopted this technique for medical examination and treatment. Angioscopy is ...

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    17. Optical Coherence Tomography: Technology and Applications Second Edition (Textbook)

      Optical Coherence Tomography: Technology and Applications Second Edition (Textbook)

      New medical imaging technologies can improve the diagnosis and clinical management of many diseases. Furthermore, advanced imaging also contributes to a better understanding of pathogenesis and therefore to the development of new pharmaceuticals and novel therapies. Thus, imaging plays a critical role in modern medical research and clinical practice. Noninvasive or minimally invasive imaging techniques have revolutionized diagnostic medicine during the last decades, e.g., X-ray computed tomography (CT), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), radioisotope imaging (position emission tomography (PET)), single-photon emission computed tomography (SPECT), and diffuse optical tomography (DOT). These techniques permit three-dimensional visualization; however ...

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    18. Mathematical Methods of Optical Coherence Tomography (Book Chapter)

      Mathematical Methods of Optical Coherence Tomography (Book Chapter)

      In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high-resolution images of the inner structure of biological tissues. Images are obtained by measuring the time delay and the intensity of the backscattered light from the sample considering also the coherence properties of light. The scattering problem is considered for a weakly scattering medium located far enough from the detector. The inverse problem is to reconstruct the susceptibility of the medium given the measurements for different positions of the mirror. Different approaches are addressed depending on the ...

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    19. Interventional Cardiology Imaging (Textbook)

      Interventional Cardiology Imaging (Textbook)

      Ever since the establishment of invasive coronary angiography, the limitations of the technique have not gone unnoticed. As a result, multiple invasive imaging modalities have been developed in an attempt to characterize the true severity of coronary artery disease as well as guide the percutaneous coronary interventions. Invasive imaging modalities have included ultrasound, optical, and chemographic technologies. Moreover, physiological assessment of the degree of the coronary blood fl ow has also been performed through fractional and coronary fl ow assessments. This book provides an overview of the current available invasive coronary imaging modalities in an attempt to present a concise ...

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    20. Optical Coherence Tomography in Neurologic Diseases (Textbook)

      Optical Coherence Tomography in Neurologic Diseases (Textbook)

      Optical coherence tomography [OCT] provides tissue morphology imagery at much higher resolution than other imaging modalities such as MRI or ultrasound, and the machines are comparatively cheaper. It is an easy technique to perform; is non-ionizing, and therefore safe. These benefits are driving a rapid transformation of OCT, from its principal application as a research tool, into an extension of the 'neurological examination' in routine office practice. Originally used in assessing the severity of tissue damage and prognosis of multiple sclerosis and various neuro-ophthalmic conditions, OCT is increasingly used in other neurological disorders such as Parkinson's disease, ALS, and ...

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    21. Clinical OCT Angiography Atlas (Textbook)

      Clinical OCT Angiography Atlas (Textbook)

      Guide to the understanding and interpretation of Angio-OCT · Provides complete overview of technique and interpretation, including terminology · Describes use of OCT for diagnosis of ocular diseases and disorders in different parts of the eye, and future developments · Highly illustrated with more than 250 clinical images · Internationally recognised editor and author team comprising leading clinicians and researchers in ophthalmology and OCT imaging

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    22. Optical Devices in Ophthalmology and Optometry: Technology, Design Principles and Clinical Application (Textbook)

      Optical Devices in Ophthalmology and Optometry: Technology, Design Principles and Clinical Application (Textbook)

      Medical technology is a fast growing field. This new title gives a comprehensive review of modern optical technologies alongside their clinical deployment. It bridges the technology and clinical domains and will be suitable in both technical and clinical environments. It introduces and develops basic physical methods (in optics, photonics, and metrology) and their applications in the design of optical systems for use in medical technology with a special focus on ophthalmology. Medical applications described in detail demonstrate the advantage of utilizing optical-photonic methods. Exercises and solutions for each chapter help understand and apply basic principles and methods. An associated website ...

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    23. Optical Coherence Tomography Guided Laser-Cochleostomy (Textbook)

      Optical Coherence Tomography Guided Laser-Cochleostomy (Textbook)

      Despite the high precision of laser, it remains challenging to control the laser-bone ablation without injuring the underlying critical structures. Providing an axial resolution on micrometre scale, OCT is a promising candidate for imaging microstructures beneath the bone surface and monitoring the ablation process. In this work, a bridge connecting these two technologies is established. A closed-loop control of laser-bone ablation under the monitoring with OCT has been successfully realised.

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    24. Optical Coherence Tomography (Textbook)

      Optical Coherence Tomography (Textbook)

      This book presents the state-of-the-art information regarding optical coherence tomography. Optical coherence tomography (OCT) is an imaging technique providing high-resolution cross-sectional images in several fields of engineering and medicine. OCT images are created by measuring the intensity of reflected or back scattered light which is scanned across the tissue and material. The aim of this book is to present elaborative information on OCT in a wide spectrum of fields including oncology, engineering, ophthalmology and atherosclerosis

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