1. Articles in category: Probes

    241-264 of 384 « 1 2 ... 8 9 10 11 12 13 14 15 16 »
    1. Apparatus of measuring glucose concentration by using optical coherence tomography and method of operating the apparatus

      Apparatus of measuring glucose concentration by using optical coherence tomography and method of operating the apparatus
      Disclosed is an apparatus and method for measuring glucose concentration by using Optical Coherence Tomography (OCT), and more particularly, an apparatus and method for increasing the blood volume around a measurement part by using a blood concentrating device and noninvasively measuring glucose concentration of the measuring portion by using OCT. A glucose concentration measuring apparatus and method using OCT according to the invention can noninvasively measure glucose concentration by using OCT and help a user to easily measure glucose concentration.
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    2. Common path systems and methods for frequency domain and time domain optical coherence tomography using non-specular reference reflection and a delivering device for optical radiation with a partially optically transparent non-specular reference reflector

      Common path systems and methods for frequency domain and time domain optical coherence tomography using non-specular reference reflection and a delivering device for optical radiation with a partially optically transparent non-specular reference reflector
      Provided are common path frequency domain and time domain OCT systems and methods that use non-specular reference reflection for obtaining internal depth profiles and depth resolved images of samples. Further provided is a delivering device for optical radiation, preferably implemented as an optical fiber probe with a partially optically transparent non-specular reflector placed in the vicinity of an associated sample. High frequency fringes are substantially reduced and a stable power level of the reference reflection is provided over the lateral scanning range. The partially optically transparent non-specular reflector is implemented as a coating placed on the interior surface of the ...
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    3. New collaboration targets skin cancer with hybrid imaging probe

      New collaboration targets skin cancer with hybrid imaging probe

      A new collaboration between researchers at King’s Health Partners Academic Health Sciences Centre and an innovative British company is targeting skin cancer with a new type of imaging probe. The £98,500 research project has received 75% funding through a National Institute for Health Research (NIHR) Invention for Innovation ‘i4i’ grant awarded to the partners, Guy’s and St Thomas’ NHS Foundation Trust, King’s College London and Michelson Diagnostics Ltd.   The aim of the project is to develop and test a hybrid imaging probe that combines the advantages of Michelson Diagnostics’ novel Multi-Beam OCT (Optical Coherence Tomography) probe ...

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    4. OCT probe for eliminating ghost images

      OCT probe for eliminating ghost images
      An OCT probe has a sheath to be inserted into a subject; and an optical system within the sheath, for changing the direction of light which propagates from a light source through an optical fiber to irradiate the light onto the subject through a transparent portion of the sheath, and for reflecting the light beam, which is reflected by the subject, to guide the light into the optical fiber. A light output surface, for causing the light to be output from the reflecting surface in a direction obliquely inclined with respect to the inner surface of the sheath, and a ...
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    5. High-resolution coregistered intravascular imaging with integrated ultrasound and optical coherence tomography probe

      High-resolution coregistered intravascular imaging with integrated ultrasound and optical coherence tomography probe
      We report an integrated ultrasound (US) and optical coherence tomography (OCT) probe and system for intravascular imaging. The dual-function probe is based on a 50 MHz focused ring US transducer, with a centric hole for mounting OCT probe. The coaxial US and light beams are steered by a 45° mirror to enable coregistered US/OCT imaging simultaneously. Lateral resolution of US is improved due to focused ultrasonic beam. Mirror effects on US were investigated and in vitro imaging of a rabbit aorta has been carried out. The combined US-OCT system demonstrated high resolution in visualizing superficial arterial structures while retaining ...
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    6. Endoscopic cross-polarization spectrometer as an instrument for puncture diagnostics

      Endoscopic cross-polarization spectrometer as an instrument for puncture diagnostics
      A modification of the polarization reflection spectroscopy method is proposed with the use of a polarizationmaintaining singlemode fiber. The choice of the fiber made it possible to create an optimal self consistent system for the illumination of a biological tissue and the reception of scattered radiation and to cre ate a probe compatible with any endoscopic equipment. The first clinical results of diagnosing tumor diseases with the created instrument showed that it is possible to determine the tumor–norm boundary, which is very important for organpreserving operations. All of the results obtained by this method agree well ...
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    7. Semi-resonant operation of a fiber-cantilever piezotube scanner for stable optical coherence tomography endoscope imaging

      Semi-resonant operation of a fiber-cantilever piezotube scanner for stable optical coherence tomography endoscope imaging
      A forward-view optical coherence tomography (OCT) scanning catheter has been developed based on a fiber-cantilever piezotube scanner by using a semi-resonant scan strategy for a better scan performance. A compact endoscope catheter was fabricated by using a tubular piezoelectric actuator with quartered electrodes in combination with a resonant fiber cantilever. A cantilever weight was attached to the fiber cantilever to reduce the resonance frequency down to 63 Hz, well in the desirable range for Fourier-domain OCT. The resonant-cantilever scanner was driven at semi-resonance frequencies that were well out of the resonance peak but within a range of partial resonance. This ...
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    8. Flexible Curled Optical Cord for Bending-Insensitive Optical Imaging Delivery

      Flexible Curled Optical Cord for Bending-Insensitive Optical Imaging Delivery

      In the application of optical imaging technologies to the biomedical field, the flexible optical cord is one of the key components used to deliver the reflected optical signal from the internal biological tissue to the biomedical imaging system. However, the conventional optical fibers suffer from a critical wiring limitation, which results in severe power losses under a small bending radius that is less than a few centimeters. In this paper, we demonstrate that holey optical fibers with 18 air holes in cladding have negligible bending loss under a minimum bending radius of 3 mm. Excellent bending insensitivity of the holey ...

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    9. Multi-Function Optical Probe System For Medical And Veterinary Applications (Wo 2010/104752)

      Multi-Function Optical Probe System For Medical And Veterinary Applications (Wo 2010/104752)
      A device includes a handpiece having a probe tip disposed at an end thereof, and, connected to the handpiece such that, at the probe tip, a functionality of each is provided, a plurality of probes. The probes may include an optical coherence tomography (OCT) probe, an endoillumination probe, a laser therapy probe, an ultrasound imaging probe, an electrocautery probe, an RF ablation probe, a cryosurgical probe, an irrigator, and/or a mechanical probe.
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    10. Surgical microscope having an OCT-system

      Surgical microscope having an OCT-system
      A surgical microscope (100) has viewing beams (109a, 109b) passing through a microscope imaging optic which includes a microscope main objective system (101) having a magnification system of variable magnification. The microscope imaging optic transposes a convergent viewing beam (109a, 109b) from the object region (114) into a parallel beam. The surgical microscope includes an OCT-system (120) for examining the object region (114). The OCT-system (120) makes available an OCT-scanning beam (190) which is guided through the microscope imaging optic.
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    11. Method and apparatus for measurement of optical properties in tissue

      Method and apparatus for measurement of optical properties in tissue
      A method of analyzing tissue includes inserting a radiation source into tissue, impinging radiation upon the tissue, obtaining a sample signal of the radiation that impinges upon the tissue, and determining a refractive index of the tissue from the sample signal. The method may also include determining at least one other optical property of the tissue. The method may provide for identifying tissue as part of a biopsy method. A device for analyzing tissue may include a low-coherence interferometer and a probe optically coupled to the interferometer, where the probe includes a radiation source.
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    12. Robust High-Resolution Fine OCT Needle for Side-Viewing Interstitial Tissue Imaging

      Robust High-Resolution Fine OCT Needle for Side-Viewing Interstitial Tissue Imaging
      Fine optical coherence tomography (OCT) imaging needles that can be integrated with a standard biopsy needle have been developed with a new optics design to improve the optical quality and mechanical robustness, where a fiber-optic lens (that is spliced to a single-mode fiber) and a microreflector are encased within a microglass tube. The design also minimizes the cylindrical lens effect induced by the glass tube and eases the needle assembly process. Real-time cross-sectional OCT imaging of various tissue samples were performed ex vivo using the miniature-imaging needle along with a 1300-nm swept-source OCT system. The preliminary results demonstrate the improved ...
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    13. Endoscopic Functional Fourier Domain Common-Path Optical Coherence Tomography for Microsurgery

      Endoscopic Functional Fourier Domain Common-Path Optical Coherence Tomography for Microsurgery
      A single-arm interferometer-based optical coherence tomography (OCT) system known as common-path OCT (CP-OCT) is rapidly progressing towards practical application. Due in part to the simplicity and robustness of its design, Fourier domain CP-OCT (FD-CP-OCT) offers advantages in many endoscopic sensing and imaging applications. FD-CP-OCT uses simple, interchangeable fiber optic probes that are easily integrated into small and delicate surgical tools. The system is capable of providing not only high-resolution imaging but also optical sensing. Here, we report progress towards practical application of FD-CP-OCT in the setting of delicate microsurgical procedures such as intraocular retinal surgery. To meet the challenges presented ...
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    14. In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography

      In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography
      The use of microneedles as a method of circumventing the barrier properties of the stratum corneum is receiving much attention. Although skin disruption technologies and subsequent transdermal diffusion rates are being extensively studied, no accurate data on depth and closure kinetics of microneedle-induced skin pores are available, primarily due to the cumbersome techniques currently required for skin analysis. We report on the first use of optical coherence tomography technology to image microneedle penetration in real time and in vivo. We show that optical coherence tomography (OCT) can be used to painlessly measure stratum corneum and epidermis thickness, as well as ...
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    15. Multimodal Depth-Resolving Endoscope

      Multimodal Depth-Resolving Endoscope
      A fiber-optic multimodal multi-spectral (MS), Optical Coherence Tomography (OCT), photoacoustic (PA) endoscope with beam scanning by a two-dimensional Microelectromechanical systems (MEMS) scanner present in the endoscopic head, combined in a synergetic way in a single endoscopic system. The PA, OCT and MS light sources are coupled to the endoscopic head through an optical switcher. Using a single optical endoscopic head and an electro-optical switch the endoscope of the invention is capable of sequential or parallel MS, OCT and PA imaging. The endoscope provides real-time imaging with a rate of 5 to 60 frames per second for each of the three ...
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    16. Miniature Non-MEMS Scanner For Small Size Imaging Systems

      Miniature Non-MEMS Scanner For Small Size Imaging Systems
      The SMALLEST available non-MEMS Resonant Scanner currently on the market was developed by Electro-Optical Products Corp. is a miniature electromagnetically driven moving mirror device (0.9 x 0.5 x 0.4 inches), which deflects a light beam with a continuous sinusoidal motion. EOPC's technology offers 6 mm diameter, 7x7 mm and 12x7 mm size mirrors, with an optical scanning angle up to 50°, and a fixed-frequency scanning range from 100 to 1000 Hz, fixed at any one value within the range. AGC type driver provides: •both sine wave and TTL level square wave reference signals •trimpot control to ...
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    17. System and method for identifying tissue using low-coherence interferometry

      System and method for identifying tissue using low-coherence interferometry
      An apparatus for needle biopsy with real time tissue differentiation using one dimensional interferometric ranging imaging, comprising a biopsy device having a barrel and a needle, an optical fiber inserted in the needle, and a fiber optic imaging system connected to the optical fiber. The imaging system obtains images and compares the optical properties and patterns to a database of normalized tissue sample images to determine different tissue types. The physician performing the biopsy obtains feedback via a feedback unit associated with the biopsy device and which is connected to the imaging system. The feedback unit can provide visual, audible ...
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    18. Interference objective for annular test surfaces

      Interference objective for annular test surfaces
      An apparatus including: an interferometric objective comprising a beam splitter surface configured to separate input light into test light and reference light, and a reference surface configured to receive the reference light and direct it back to the beam splitter surface, which is configured to recombine the reference light with test light reflected from a test surface, the interferometric objective further comprising one or more optical elements positioned in the path of the input light and having positive or negative optical power, wherein the reference surface is curved and defines a window to pass the input light towards the beam ...
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      Mentions: Zygo
    19. Forward-viewing resonant fiber-optic scanning endoscope of appropriate scanning speed 
for 3D OCT imaging

      Forward-viewing resonant fiber-optic scanning endoscope of appropriate scanning speed 
for 3D OCT imaging
      A forward-viewing resonant fiber-optic endoscope of a scanning speed appropriate for a high-speed Fourier-domain optical coherence tomography (FD-OCT) system was developed to enable real-time, three-dimensional endoscopic OCT imaging. A new method was explored to conveniently tune the scanning frequency of a resonant fiber-optic scanner, by properly selecting the fiber-optic cantilever length, partially changing the mechanical property of the cantilever, and adding a weight to the cantilever tip. Systematic analyses indicated the resonant scanning frequency can be tuned over two orders of magnitude spanning from ~10Hz to ~kHz. Such a flexible scanning frequency range makes it possible to set an appropriate ...
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    20. Optical scanning system

      Optical scanning system
      The present application is directed to an optical scanning system for medical applications, preferably in ophthalmology, which can be used for a large range of diagnostic and therapeutic applications. The optical scanning system comprises at least one controllable reflector which has an actuator and which is arranged in a first imaging beam path for deflecting at least one therapy beam and/or diagnosis beam over a work field in a scanning manner, a second imaging beam path for a fixation beam which is imaged on the work field in a spatially fixed manner with respect to the optical axis of ...
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    21. Atherectomy system with imaging guidewire

      Atherectomy system with imaging guidewire
      Systems and methods of increasing blood flow in a blood vessel with ultraluminal plaque. One disclosed method includes inserting an imaging guidewire into the blood vessel to the intraluminal plaque, propelling a catheter with a working head over the guidewire towards the distal end of the guidewire, scanning with the imaging guidewire to generate a cross-section image, radially positioning the catheter using a positioning element, monitoring the image to ascertain that the working head is properly positioned and operating the working head to remove the plaque. A computerized system designed, constructed and configured to perform the methods is further disclosed.
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    22. Volcano Introduces Vibe™ Rx - the World's Only Vascular Imaging Balloon Catheter

      Volcano Introduces Vibe™ Rx - the World's Only Vascular Imaging Balloon Catheter
      Volcano Corporation (NASDAQ: VOLC) announced today that it has received CE Mark approval for the VIBE™ RX Vascular Imaging Balloon Catheter. The company also announced that it has completed its first clinical cases with the VIBE™ RX in New Zealand. A single VIBE™ RX Catheter can quickly access, prepare, and assess challenging lesions. IVUS guidance provides precise, targeted balloon dilatation with immediate confirmation of interventional results. "VIBE™ RX represents the first of what we believe will be many Volcano image-guided therapy devices designed to allow physicians to see more detail right at the point of the therapy," commented Scott Huennekens ...
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    23. Access system

      Access system
      The invention provides systems and methods for providing access to a target site. Example systems may include a needle, a grid to guide the needle, a plate with an aperture, a member coupled to the plate and including a semispherical surface, and a hub slideably coupled to the plate by a guide. The system may also include a needle coupled to the hub, the needle including a magnetically trackable sensor positioned in a tip of the needle. The semispherical surface can be positioned against skin of a body and the hub slid relative to the plate along the guide to ...
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    24. 3D In Vivo optical coherence tomography based on a low-voltage, large-scan-range 2D MEMS mirror

      3D In Vivo optical coherence tomography based on a low-voltage, large-scan-range 2D MEMS mirror
      3D in vivo optical imaging on a mouse has been obtained using a 2D MEMS mirror for lateral scanning in a time-domain optical coherence tomography (OCT) system. The MEMS mirror aperture size is 1 × 1 mm2, and the device footprint is 2 × 2 mm2. The MEMS mirror scans ± 30° optical angles about both x and y-axis at only 5.5V DC voltage. An endoscopic probe with an outer diameter of 5.8 mm has been designed, manufactured and packaged. The probe scans an average transverse area of 2 mm × 2 mm. The imaging speed of the probe is about 2 ...
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    241-264 of 384 « 1 2 ... 8 9 10 11 12 13 14 15 16 »
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  2. Popular Articles

  3. Organizations in the News

    1. (1 articles) Center for Ophthalmic Optics and Lasers
    2. (1 articles) Harvard University
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    5. (1 articles) FEMTO-ST Institute
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  4. People in the News

    1. (1 articles) Guillermo J. Tearney
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  5. OCT Companies in the News

    1. (1 articles) Physical Sciences Incorporated
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