1. Articles in category: Probes

    1-24 of 441 1 2 3 4 ... 17 18 19 »
    1. Interferometric force sensor for surgical instruments

      Interferometric force sensor for surgical instruments

      A surgical tool system according to an embodiment of the current invention includes a surgical tool, and an interferometry system optically coupled to the surgical tool. The surgical tool includes a body section, a sensor section at least one of attached to or integral with the body section, and a surgical section at least one of attached to or integral with the sensor section at an opposing end of the sensor section from the body section. The sensor section comprises an interferometric optical sensor defining a reference distance that changes in response to at least one of a force or ...

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    2. Design and fabrication of an optical probe with a phase filter for extended depth of focus

      Design and fabrication of an optical probe with a phase filter for extended depth of focus

      The trade-off between spot size and depth of focus (DOF) often limits the performance of optical systems, such as optical coherence tomography and optical tweezers. Although researchers have proposed various methods to extend the DOF in free-space optics, many are difficult to implement in miniaturized optical probes due to space limitations. In this study, we present an optical probe with an extended DOF using a binary phase spatial filter (BPSF). The BPSF pattern was fabricated on the distal tip of an optical probe with a diameter of 1 mm by replica molding soft lithography, which can be easily implemented in ...

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    3. Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy

      Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy

      Optical coherence tomography (OCT) is an optical diagnostic modality that can acquire cross-sectional images of the microscopic structure of the esophagus, including Barrett’s esophagus (BE) and associated dysplasia. We developed a swallowable tethered capsule OCT endomicroscopy (TCE) device that acquires high-resolution images of entire gastrointestinal (GI) tract luminal organs. This device has a potential to become a screening method that identifies patients with an abnormal esophagus that should be further referred for upper endoscopy. Currently, the characterization of the OCT-TCE esophageal wall data set is performed manually, which is time-consuming and inefficient. Additionally, since the capsule optics optimally focus ...

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    4. Rotational distortion correction in endoscopic optical coherence tomography based on speckle decorrelation

      Rotational distortion correction in endoscopic optical coherence tomography based on speckle decorrelation

      We present a new technique for the correction of nonuniform rotation distortion in catheter-based optical coherence tomography (OCT), based on the statistics of speckle between A-lines using intensity-based dynamic light scattering. This technique does not rely on tissue features and can be performed on single frames of data, thereby enabling real-time image correction. We demonstrate its suitability in a gastrointestinal (GI) balloon-catheter OCT system, determining the actual rotational speed with high temporal resolution, and present corrected cross-sectional and en face views showing significant enhancement of image quality.

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    5. Method and system for optically evaluating proximity to the inferior alveolar nerve in situ

      Method and system for optically evaluating proximity to the inferior alveolar nerve in situ

      A low coherence interferometry probe system for evaluating proximity to a tissue layer, comprising a low coherence light source, an excitation optical fiber to bring the low coherence excitation light near the tissue layer and a collection optical fiber for capturing back-scattered light from the tissue layer. The probe system comprises an interferometry sub-system and a processor for evaluating a distance to the tissue layer. There is also provided a spectral absorption probe system for evaluating proximity to an artery, comprising a light source excitation light having a wavelength adapted for absorption by blood chromophores, an excitation optical fiber and ...

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    6. Durable single mode fiber probe with optimized reference reflectivity

      Durable single mode fiber probe with optimized reference reflectivity

      A probe for a common path optical coherence tomography system includes a sheath having a proximal end and a distal end and defining a lumen therein, a single mode optical fiber disposed within the lumen of the sheath such that a portion of the single mode optical fiber extends beyond the distal end of the sheath. The single mode optical fiber has an end face for transmitting and receiving light. The probe also includes a layer of hardened epoxy encasing the portion of the single mode optical fiber that extends beyond the distal end of the sheath except for the ...

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    7. Flashlight-Sized Probe Can Spot Cancer Cells in Real Time

      Flashlight-Sized Probe Can Spot Cancer Cells in Real Time

      Malignant tumor strongholds and their microscopic spies can’t hide in the thicket of flesh much longer, for surgeons have a new weapon: a device that sheds light on their location. Literally. “Any state of disease will alter the cells and molecules in our body,” said Dr. Stephen Boppart, a professor of bioengineering at the University of Illinois who invented the device. Every molecule scatters light different ways, he said, “leaving a distinct optical scattering signature.” The new device senses cancer cells’ unique signatures, letting surgeons know which areas around the tumor are cancerous and which are safe to leave ...

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    8. Monitoring disposition of tethered capsule endoscope in esophagus

      Monitoring disposition of tethered capsule endoscope in esophagus

      A scanning flexible endoscope includes a tether attached to a capsule. The tether controls a disposition of the capsule within a body lumen such as the esophagus. A scanning device in the capsule optically scans the adjacent tissue on the inside surface of the body lumen as the capsule is moved axially through the body lumen. A non-contact sensor responds to indicia on the tether to measure a relative position of the tether and the capsule in the body lumen. The indicia can be analog or digital in form and the sensor can be either magnetic, or optical. A wiper ...

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    9. Expanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope

      Expanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope

      Optical coherence tomography (OCT) is a useful imaging modality for detecting and monitoring diseases of the gastrointestinal tract and other tubular structures. The non-destructiveness of OCT enables time-serial studies in animal models. While turnkey commercial research OCT systems are plenty, researchers often require custom imaging probes. We describe the integration of a custom endoscope with a commercial swept-source OCT system and generalize this description to any imaging probe and OCT system. A numerical dispersion compensation method is also described. Example images demonstrate that OCT can visualize the mouse colon crypt structure and detect adenoma in vivo .

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    10. Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery

      Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery

      Wide local excision (WLE) is a common surgical intervention for solid tumors such as those in melanoma, breast, pancreatic, and gastrointestinal cancer. However, adequate margin assessment during WLE remains a significant challenge, resulting in surgical reinterventions to achieve adequate local control. Currently, no label-free imaging method is available for surgeons to examine the resection bed in vivo for microscopic residual cancer. Optical coherence tomography (OCT) enables real-time high-resolution imaging of tissue microstructure. Previous studies have demonstrated that OCT analysis of excised tissue specimens can distinguish between normal and cancerous tissues by identifying the heterogeneous and disorganized microscopic tissue structures indicative ...

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    11. Aberration corrected short working distance optical probe with large confocal parameter

      Aberration corrected short working distance optical probe with large confocal parameter

      An optical probe is provided. The optical probe includes a lens extending along an axis between a first end and a second end. A spacer extends along the axis between a first end and a second end. The first end of the spacer is connected to the second end of the lens. A prism is connected to the second end of the spacer such that the prism is spaced apart from the lens by the spacer.

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    12. High spatial resolution optical coherence tomography rotation catheter

      High spatial resolution optical coherence tomography rotation catheter

      An optical coherence tomography rotation catheter comprises a catheter body and a tubular member that rotates around a longitudinal axis in the catheter body. An optical fiber extends along an interior of the tubular member and has an optical fiber distal end. A light reflecting member is distal of the optical fiber distal end and rotates around the longitudinal axis with the tubular member. The light reflecting member includes a light reflecting surface which is spaced from and faces the optical fiber distal end and which is inclined to reflect the light from the optical fiber in a radial direction ...

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      Mentions: St. Jude Medical
    13. Optical probe and optical measuring method

      Optical probe and optical measuring method

      An optical measurement method that can suppress variation in detection sensitivity even if an optical probe is bent, and an optical probe suitably used for the method are provided. An optical probe 10 includes an optical fiber 11 that transmits light between a proximal end 11a and a distal end 11b, an optical connector 12 connected with the optical fiber 11 at a side of the proximal end 11a, a focusing optical system 13 and a deflecting optical system 14 optically connected with the optical fiber 11 at a side of the distal end 11b, and a support tube 15 ...

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    14. Catheter-based off-axis optical coherence tomography imaging system

      Catheter-based off-axis optical coherence tomography imaging system

      Catheter-based Optical Coherence Tomography (OCT) systems utilizing an optical fiber that is positioned off-axis of the central longitudinal axis of the catheter have many advantage over catheter-based OCT systems, particularly those having centrally-positioned optical fibers or fibers that rotate independently of the elongate body of the catheter. An OCT system having an off-axis optical fiber for visualizing the inside of a body lumen may be rotated with the body of the elongate catheter, relative to a handle portion. The handle may include a fiber management pathway for the optical fiber that permits the off-axis optical fiber to rotate with the ...

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    15. Method and measuring device for gauging surfaces

      Method and measuring device for gauging surfaces

      In a method for gauging surfaces (7''), in which a frequency-modulated laser beam is generated, the laser beam is emitted onto the surface as measuring radiation (MS), the measuring radiation (MS) backscattered from the surface (7'') is received and the distance between a reference point and the surface (7'') is measured interferometrically, wherein the measuring radiation (MS) is emitted and received while the surface to be gauged is being scanned, and a measuring arm and a reference interferometer arm with a partially common beam path are used, deviations from the essentially perpendicular impingement of the measuring radiation (MS) on the ...

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      Mentions: Leica
    16. Mirror Based Microelectromechanical Systems And Methods

      Mirror Based Microelectromechanical Systems And Methods

      Unlike most MEMS device configurations which simply switch between two positions in many optical devices the state of a MEMS mirror is important in all transition positions. It may determine the characteristics of an optical delay line system and by that an optical coherence tomography system in one application and in another the number of wavelength channels and the dynamic wavelength switching capabilities in the other.

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    17. Lasers and SLEDs for optical coherence tomography

      Lasers and SLEDs for optical coherence tomography

      Optical coherence tomography (OCT) allows for the generation of 3D tomographic images of sub-surface structures in-vivo. This non-destructive, non-ionising process has found application in biological science and clinical diagnosis. Specifically, two versions of the OCT technique have proved optimal for different applications. For retinal imaging through a long length of water, near infrared wavelength super-luminescent diodes (SLEDs) with silicon array detector spectrometer systems have dominated. For imaging turbid media such as skin, Rayleigh scattering favours a longer wavelength in order to achieve suitable penetration depth. As such, the silicon detector is no longer suitable and the optimum system is now ...

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    18. Miniature endoscopic optical coherence tomography for calculus detection

      Miniature endoscopic optical coherence tomography for calculus detection

      The effective treatment of periodontitis involves the detection and removal of subgingival dental calculus. However, subgingival calculus is more difficult to detect than supragingival calculus because it is firmly attached to root surfaces within periodontal pockets. To achieve a smooth root surface, clinicians often remove excessive amounts of root structure because of decreased visibility. In addition, enamel pearl, a rare type of ectopic enamel formation on the root surface, can easily be confused with dental calculus in the subgingival environment. In this study, we developed a fiber-probe swept-source optical coherence tomography (SSOCT) technique and combined it with the quantitative measurement ...

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    19. Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry

      Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry

      A novel radiofrequency ablation catheter has been developed with integrated custom designed optics, enabling real-time monitoring of radiofrequency ablation procedures through polarization-sensitive optical coherence reflectometry. The optics allow for proper tissue illumination through a view-port machined in the catheter tip, thus providing lesion depth control over the RF ablation treatment. The system was verified in an in-vitro model of swine myocardium. Optical performance and thermal stability was confirmed after more than 25 procedures, without any damage to the optical assembly induced by thermal stress or material degradation. The use of this catheter in RF ablation treatments may make possible to ...

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    20. Methods and systems for optical imaging or epithelial luminal organs by beam scanning thereof

      Methods and systems for optical imaging or epithelial luminal organs by beam scanning thereof

      Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a ...

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    21. A Micromotor Catheter for Intravascular Optical Coherence Tomography

      A Micromotor Catheter for Intravascular Optical Coherence Tomography

      We have developed a new form of intravascular optical coherence tomography (IV-OCT) that allows the extremely fast acquisition of high-resolution images of the coronary arteries. This process leads to much better image quality by eliminating cardiac motion artefacts and undersampling. It relies on a catheter that incorporates a synchronous micromotor with a diameter of 1.0 mm and a rotational speed of up to 5600 revolutions per second, enabling an IV-OCT frame rate of 5.6 kHz. This speed is matched by a wavelength-swept laser that generates up to 2.8 million image lines per second. With this setup, our ...

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    22. Enhanced Optical Coherence Vibration Tomography for Subnanoscale-Displacement-Resolution Calibration of Piezoelectric Actuators

      Enhanced Optical Coherence Vibration Tomography for Subnanoscale-Displacement-Resolution Calibration of Piezoelectric Actuators

      We report a sub nanoscale-displacement-resolution optical coherence vibration tomography (SOCVT) system for real-time calibration of piezoelectric actuators. The calibrations of the actuators at nanoscale or microscale displacement ranges were performed by varying the input voltage over the entire range in the ascending and descending directions. The computational and experimental results demonstrated that the developed SOCVT could be used to characterizethe dynamic hysteretic behaviour, nonlinear effect, and impulsive behaviour of piezoelectric actuators. The SOCVT technique is non-contact and non-invasive in nature, making it ideal for real-time and in situ ultra-precision calibration of piezoelectric actuators, which are widely used in active vibration ...

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    23. Rapid scanning catheterscope for expanded forward-view volumetric imaging with optical coherence tomography

      Rapid scanning catheterscope for expanded forward-view volumetric imaging with optical coherence tomography

      We demonstrate a novel catheterscope, based on scanning fiber endoscopy, for volumetric imaging with optical coherence tomography (OCT), which possesses a high resonance frequency ( > 2     kHz ) and a small outer diameter (OD) (1.07 mm). Our design is the fastest volumetric-scanning, forward-viewing catheterscope for OCT, and the scanning package has the smallest OD of any such OCT package published to date. Using a proof-of-operation catheterscope with commercial lenses, we demonstrate high-quality in vivo and ex vivo volumetric imaging and extend the 1.1 mm diameter field of view more than 200-fold by mosaicking. Due to its small OD, short rigid ...

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    24. Miniature probe integrating optical-resolution photoacoustic microscopy, optical coherence tomography, and ultrasound imaging: proof-of-concept

      Miniature probe integrating optical-resolution photoacoustic microscopy, optical coherence tomography, and ultrasound imaging: proof-of-concept

      In this Letter, we present a novel tri-modal miniature side-view probe, through which optical-resolution photoacoustic microscopy (OR-PAM), optical coherence tomography (OCT), and pulse-echo ultrasound (US) images can be coaxially acquired and displayed simultaneously. The probe consists of a common optical path for OR-PAM (light delivery) and OCT (light delivery/detection), and a 40-MHz unfocused ultrasound transducer for OR-PAM (photoacoustic detection) and US (ultrasound transmission/receiving) with an overall diameter of 2 mm. Combining OR-PAM, OCT, and US would provide complementary information including optical absorption (OR-PAM), optical back-scattering (OCT), and deep tissue structures (US) about biological tissue. Based on an integrated ...

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    1-24 of 441 1 2 3 4 ... 17 18 19 »
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    1. (1 articles) Xuan Liu
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