Probes -Optical Coherence Tomography News

Articles in category: Probes

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1. Feature Of The Week 5/5/13: University of Maryland Reports Interesting Results on OCT Needle Probe Used In Conjunction with Magnetic Resonance Imaging for Precision Surgical Procedures
  
  Explore Optical Coherence Tomography News May 5 2013 Probes
  
  We develop a novel platform based on a tele-operated robot to perform high-resolution optical coherence tomography (OCT) imaging under continuous large field-of-view magnetic resonance imaging (MRI) guidance. Intra-operative MRI (iMRI) is a promising guidance tool for high-precision surgery, but it may not have sufficient resolution or contrast to visualize certain small targets. To address these limitations, we develop an MRI-compatible OCT needle probe, which is capable of providing microscale tissue architecture in conjunction with macroscale MRI tissue morphology in real time. Coregistered MRI/OCT images on ex vivo chicken breast and human brain tissues demonstrate that the complementary imaging scales ...
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  Mentions: University of Maryland Yu Chen Chia-Pin Liang
2. Collecting optical coherence elastography depth profiles with a micromachined cantilever probe
  
  Explore opticsinfobase.org Apr 24 2013 Probes
  
  We present an experimental setup that combines optical coherence elastography depth sensing with atomic force microscope indentation. The instrument relies on a miniaturized cantilever probe that compresses a sample with a small footprint force and simultaneously collects an optical coherence tomography (OCT) depth profile underneath the indenting point. The deflection of the cantilever can be monitored via optical fiber interferometry with a resolution of 2 nm. The OCT readout then provides depth profiles of the subsurface layer deformation with 15 nm resolution and depth range of a few millimeters.
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  Mentions: Johannes F. de Boer Medical University of Vienna
3. Experimental and Theoretical Investigation of Common Path Optical Coherence Tomography Using Conical Tip Lens Fiber
  
  Explore IOPscience Apr 12 2013 Probes
  
  We proposed Common Path Optical Coherence Tomography (CPOCT) using gold coated conical tip lens fiber with a central wavelength of 1310 nm SLD to improve lateral resolution under the water. We already verified that conical tip lens fiber was good to improve the lateral resolution in CPOCT in air. However, CPOCT using conical tip lens fiber could not be functioning under the water solution because the value of back-reflected light field from the conical tip was too low. For this reason, we had to set reference intensity at a high level by coating the tip with a thin layer of ...
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4. Electrostatic Micromachined Resonating Micro-Scanner for Circumferential Endoscopic Bio-Imaging
  
  Explore IEEE Xplore Apr 4 2013 Probes
  
  An electrostatic actuation-based resonating microelectromechanical systems (MEMS) polygonal mirror micro-scanner is developed for endoscopic probes used in clinical investigations. Microassembly technology is utilized to construct this device, which consists of a micro-actuator of four sets of electrostatic comb-drive resonators and an eight-slanted-facet highly reflective pyramidal polygon micro-reflector. The pyramidal polygon micro-reflector is developed using high precision diamond turning and soft lithography molding technologies. An optical scan angle of near-360 degrees is achieved at a resonant frequency of 180 Hz when driven by electrostatic comb-drive resonators with 80 Vpp ac voltage.
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  Mentions: National University of Singapore
5. Optical probe and optical system therefor
  
  Explore uspto.gov Apr 2 2013 Patents , Probes
  
  An optical probe and an optical system therefor are provided. The optical probe is includes a housing configured to house the optical system and the housing has a transparent window therein. the optical system includes a light emitting unit, a collimation lens, and a focusing lens. A numerical aperture of the optical system is adjustable by adjusting a pupil diameter of the collimation lens and a focal length of the focusing lens. The pupil diameter of the collimation lens is adjustable based on a variable focal lens or by adjusting a distance between the collimation lens and the light emitting ...
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6. Sapphire ball lensed fiber probe for common-path optical coherence tomography in ocular imaging and sensing
  
  Explore Conference Proceedings Apr 1 2013 Ophthalmology , Probes
  
  We describe a novel common-path optical coherence tomography (CP-OCT) fiber probe design using a sapphire ball lens for cross-sectional imaging and sensing in retina vitrectomy surgery. Single mode Gaussian beam (TEM 00 ) simulation was used to optimize lateral resolution and working distance (WD) of the common-path probe. A theoretical sensitivity model for CP-OCT was prosed to assess its optimal performance based an unbalanced photodetector configuration. Two probe designs with working distances (WD) 415μm and 1221μm and lateral resolution 11μm and 18μm, respectively were implemented with sensitivity up to 88dB. The designs are also fully compatible with ...
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  Mentions: Johns Hopkins University Jin U. Kang Mingtao Zhao
7. Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology
  
  Explore Conference Proceedings Apr 1 2013 Gastroenterology , Probes
  
  We developed a micro-motor based miniature catheter with an outer diameter of 3mm for ultrahigh speed endoscopic optical coherence tomography (OCT) using vertical cavity surface-emitting laser (VCSEL) at a 1MHz axial scan rate. The micro-motor can rotate a micro-prism at 1,200-72,000rpm (corresponding to 20- 1,200fps) with less than 5V driving voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back for a long distance to acquire three-dimensional (3D) dataset covering a large area on the specimen. VCSEL provides high a-line rate to support ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs
8. Spiral-scanning, side-viewing optical coherence tomography endoscope for three-dimensional fully sampled in vivo imaging of the mouse colon
  
  Explore Conference Proceedings Mar 18 2013 Gastroenterology , Probes
  
  We have previously developed side-viewing endoscopic OCT systems to detect colorectal cancer in the murine model, which longitudinally scans the mouse colon at 8-16 discrete angular positions. This small number of angles is chosen to keep imaging time and the amount of data to analyze reasonable, but this azimuthal undersampling of the tissue may result in missed or incorrectly characterized adenomas. A need exists for a spiral-scanning OCT endoscope capable of generating 3D, in vivo OCT data sets that satisfy the Nyquist criterion for adequate sampling of the tissue. Our new endoscopic system replaces the sample arm optics of a ...
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  Mentions: Jennifer K. Barton University of Arizona
9. Accurate Modeling and Design of Graded-Index Fiber Probes for Optical Coherence Tomography using the Beam Propagation Method
  
  Explore IEEE Xplore Mar 18 2013 Probes
  
  Fiber-optic probes for sensing and biomedical imaging applications such as optical coherence tomography (OCT) frequently employ sections of graded-index (GRIN) fiber to re-focus the diverging light from the delivery fiber. Such GRIN fiber microlenses often possess aberrations that cause significant distortions of the focused output beam. Current design methods based on ABCD matrix transformations of Gaussian beams cannot model such effects and are therefore inadequate for the analysis and design of high-performance probes that require diffraction-limited output beams. We demonstrate use of the beam propagation method (BPM) to analyze beam distortion in GRINlensed fibers resulting from index profiles that exhibit ...
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  Mentions: David D. Sampson University of Western Australia Dirk Lorenser
10. Miniature probe combining optical-resolution photoacoustic microscopy and optical coherence tomography for in vivomicrocirculation study
  
  Explore opticsinfobase.org Mar 13 2013 Cardiology , Microscopy , Probes
  
  Photoacoustic microscopy (PAM) is sensitive to optical absorption, while optical coherence tomography (OCT) is based on optical backscattering. Combining PAM and OCT can provide complementary information about biological tissue. Here we present a combined optical-resolution PAM (ORPAM) and OCT system that is integrated through a miniature probe with an overall diameter of 2.3 mm, suitable for insertion through a standard endoscopic or laparoscopic port during minimally invasive surgery or endoscopic exam. The hybrid probe consists of a common optical path for OCT (light delivery/detection) and ORPAM (light excitation) and a 10 MHz unfocused ultrasound transducer for photoacoustic detection ...
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  Mentions: University of Florida Huikai K. Xie
11. Integrated optical scanning image acquisition and display
  
  Explore uspto.gov Mar 12 2013 Patents , Probes
  
  An apparatus and method for providing image acquisition and/or image display in a limited region of interest (ROI). The apparatus comprises a micro-electro-mechanical system (MEMS), preferably integrating a light source, a cantilever, a lens, an actuator, a light detector, and a position sensor. The light source provides light for illuminating the ROI, displaying an image, providing a therapy, and/or performing other functions. The cantilever comprises a resin waveguide with a fixed end attached to a substrate that supports many or all other components. A free end of the cantilever is released from the substrate during fabrication and includes ...
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  Mentions: University of Washington Eric J. Seibel
12. Catheterscope 3D guidance and interface system
  
  Explore uspto.gov Feb 26 2013 Patents , Probes
  
  Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction ...
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  Mentions: University of Washington Eric J. Seibel
13. Coronal in vivo forward-imaging of rat brain morphology with an ultra-small optical coherence tomography fiber probe
  
  Explore IOPscience Jan 16 2013 Neurology , Probes
  
  A well-established navigation method is one of the key conditions for successful brain surgery: it should be accurate, safe and online operable. Recent research shows that optical coherence tomography (OCT) is a potential solution for this application by providing a high resolution and small probe dimension. In this study a fiber-based spectral-domain OCT system utilizing a super-luminescent-diode with the center wavelength of 840 nm providing 14.5 μm axial resolution was used. A composite 125 μm diameter detecting probe with a gradient index (GRIN) fiber fused to a single mode fiber was employed. Signals were reconstructed into grayscale images by ...
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  Mentions: University of Freiburg Gereon Hüttmann University of Lübeck
14. Dual-modality needle probe for combined fluorescence imaging and three-dimensional optical coherence tomography
  
  Explore opticsinfobase.org Jan 16 2013 Probes
  
  To the best of our knowledge, we present the first needle probe for combined optical coherence tomography (OCT), and fluorescence imaging. The probe uses double-clad fiber (DCF) that guides the OCT signal and fluorescence excitation light in the core and collects and guides the returning fluorescence in the large-diameter multimode inner cladding. It is interfaced to a 1310 nm swept-source OCT system that has been modified to enable simultaneous 488 nm fluorescence excitation and > 500 nm emission detection by using a DCF coupler to extract the returning fluorescence signal in the inner cladding with high efficiency. We present imaging results ...
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  Mentions: David D. Sampson University of Western Australia Polytechnique Montreal
15. Adaptive optical probe design for optical coherence tomography and microscopy using tunable optics
  
  Explore opticsinfobase.org Jan 15 2013 Microscopy , Probes
  
  We present a tunable, adaptive optical imaging probe for multimodal imaging such as optical coherence tomography and microscopy. The probe is compatible with forward-looking scanning laser imaging devices such as an endoscope. The lens configuration includes a tunable iris and two varifocal lenses, both driven by microelectrofluidics, as well as several conventional fixed focus lenses. The modulation transfer function and spot size in the focal plane is evaluated, and we show using optical simulations that there are three possible imaging modes with different transverse resolutions and focal depths. ]
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16. Optics in 2012: The Best of the Best from Optics and Photonics News (VIDEO)
  
  Explore osa-opn.org Dec 4 2012 Probes
  
  This special issue of Optics & Photonics News highlights the most exciting peer-reviewed optics research to have emerged over the past 12 months. Our panel of editors reviewed close to 80 submitted summaries from scientists all over the globe. They selected for publication the 30 stories that they felt most clearly communicated breakthroughs of interest to the optics community.
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  Mentions: David D. Sampson University of Western Australia
17. Coupling device and optical imaging device
  
  Explore uspto.gov Dec 4 2012 Patents , Probes
  
  A coupling device for coupling optical fiber cables reduces contact with the internal parts when coupling a connector. The coupling device includes a projection of a connector device housing insertable into a groove of an adapter device groove of an adapter device housing. The coupling device which connects optical fiber cables compresses an elastic member, and connects an optical fiber connector of the connector device and the optical fiber end on the adapter device side.
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  Mentions: Terumo Corporation
18. Forward looking optical coherence tomography endoscope
  
  Explore uspto.gov Dec 4 2012 Gastroenterology , Patents , Probes
  
  A forward-looking, optical coherence tomography, endoscopic probe is disclosed capable of high resolution with a small diameter. Light is focused and scanned during three passes through a lens. A light source supplies light to the proximal side of the lens. The light makes a first pass through the lens, and is reflected from a fixed mirror on the distal side. The reflected light makes a second pass from the distal side to the proximal side, and exits the lens at the proximal side, and is reflected by a scanning mirror. The light makes a third pass through the lens from ...
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19. A Microscope in a Needle
  
  Explore opticsinfobase.org Dec 1 2012 Microscopy , Probes
  
  A microscope small enough to fit into a needle creates many new possibilities for optics in medicine. We have developed a range of optical coherence tomography (OCT) needle probes. Connected to an OCT scanner via a single mode fiber, the probes are constructed by fusing exact lengths of no-core fiber and graded-index fiber to focus a broadband light beam. We terminated the optics with anglepolished, gold-coated no-core fiber to deflect the beam. Encased in a needle (outer diameter 310 ?m), these probes are capable of 3-D imaging. However, the important developments of 2012 have been where we have taken these ...
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  Mentions: David D. Sampson University of Western Australia Robert A. McLaughlin
20. Optical Coherence Tomography Probe
  
  Explore patentscope.wipo.int Dec 1 2012 Patents , Probes
  
  A miniature intraoperative probe (30) capable of forward- imaging with optical coherence tomography. The probe includes a housing (130), an actuator (150) supported by the housing, and a single mode (146) fiber supported by the housing and configured to laterally scan light data reflected from a sample..
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  Mentions: Vanderbilt University
21. A Tunable Optofluidic Silicon Optical Bench
  
  Explore IEEE Xplore Nov 30 2012 Probes
  
  A miniaturized optical bench, based on silicon micromachining and with high modularity and flexibility, is presented. This optical microsystem integrates optics, fluidics, high-precision mechanics, and focal length tunable lenses and allows the realization of numerous optical arrangements, such as telephoto and retrofocus systems. Due to its dimensions, the technology may be used for designing a variety of endoscopic imaging probes, including those for optical coherence tomography. As the measuring beam can be dynamically adapted to the surroundings and application, this microbench yields an optical system with greatly enhanced functionality and performance when compared to existing concepts.
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  Mentions: University of Freiburg
22. A 2.8-mm Imaging Probe Based On a High-Fill-Factor MEMS Mirror and Wire-Bonding-Free Packaging for Endoscopic Optical Coherence Tomography
  
  Explore IEEE Xplore Nov 30 2012 Probes
  
  This paper reports a miniature optical coherence tomography (OCT) probe and high-resolution 3-D OCT imaging results obtained with this side-view probe. The probe is only 2.8 mm in diameter, enabled by a unique high-fill-factor electrothermal MEMS mirror with hidden actuators and a novel wire-bonding-free packaging technique. The MEMS mirror has a large mirror aperture of 1 mm with a chip size of only 1.55 mm $times$ 1.7 mm $times$0.5 mm. The fabricated device achieves large 2-D scan optical angles up to 46$^{circ}$ at only 4.8 V. The specific time-domain OCT system utilized is ...
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  Mentions: University of Florida Lei Wu Huikai K. Xie
23. A novel two-axis MEMS scanning mirror with a PZT actuator for laser scanning projection
  
  Explore opticsinfobase.org Nov 21 2012 Probes
  
  This study presents a novel design for a two-axis scanning device driven by lead-zirconate-titanate (PZT) ceramic. The proposed device consists of a scanning mirror and a Y-shaped piezoelectric actuator. The scanning mirror was fabricated using an MEMS process involving three masks. Experimental results show that the fast and slow frequencies at resonance are 25.0 kHz and 0.56 kHz, respectively. The optical scanning angles are 27.6° and 39.9°. The power consumption of the device is 13.4 mW at a driving voltage of 10 V. This study also develops a laser projection module integrated with the scanning ...
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24. Mirrorcle Technologies scanning MEMS mirrors deployed in portable OCT system
  
  Explore Optical Coherence Tomography News Nov 21 2012 Other Business News , Probes
  
  Mirrorcle Technologies Inc. Press Release - Mirrorcle Technologies, Inc. (MTI), a California-based manufacturer of patented, gimbal-less beam-steering MEMS mirrors announces that the company’s devices are being used in compact hand-held probes in portable optical coherence tomography (OCT) systems. Santec Corporation, a Japan-based manufacturer of optical components, tunable lasers, optical instruments and OCT systems, chose MTI’s MEMS mirrors as the two-axis beam steering element for imaging at high, user-controllable speeds across the sample surface, obtaining of real-time 2D slice images as well as 3D images that consist of n 2D slices. Santec’s intuitive “Inner Vision” software allows users to ...
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  Mentions: Santec
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