1. Articles in category: Probes

    1-24 of 357 1 2 3 4 ... 13 14 15 »
    1. Two-dimensional optical scanner with monolithically integrated glass microlens

      Two-dimensional optical scanner with monolithically integrated glass microlens

      A miniaturized two-dimensional forward optical scanner with a monolithically integrated glass microlens was developed for microendoscopic imaging applications. The fabricated device measures 2.26 × 1.97 × 0.62 mm 3 in size and a through-silicon microlens with a diameter of 400 µm and numerical aperture of 0.37 has been successfully integrated within the silicon layer. An XY stage structure with lens shuttle and comb actuators was designed, and proprietary glass isolation blocks were utilized in mechanical and electric isolation of X- and Y -axis actuators. Resonant frequencies of the stage in X and Y directions were 3.238 and ...

      Read Full Article
    2. Endoscopic optical probe with a PZT actuator and MR tracker

      Endoscopic optical probe with a PZT actuator and MR tracker

      A miniaturized optical probe with a magnetic-resistance (MR) position tracker and piezoelectric-transduce (PZT) mirror system was developed for endoscopic optical imaging. All of the optical components such as collimation and focal lenses, reflection mirror, PZT linear actuator and MR sensor were wholly packaged in a single scanning probe with a volume of 3.57 cm 3 . This endoscopic probe has the advantages of having a small volume, extended stroke length (4.5 mm), high scanning speed (18.2 mm/s), efficient recoupling ratio (78.3%) and high spatial resolution (11.7 μm) compared to conventional endoscopes. Consequently, it showed the ...

      Read Full Article
    3. High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes

      High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes

      We report a technique for blood flow detection using split spectrum Doppler optical coherence tomography (ssDOCT) that shows improved sensitivity over existing Doppler OCT methods. In ssDOCT, the Doppler signal is averaged over multiple sub-bands of the interferogram, increasing the SNR of the Doppler signal. We explore the parameterization of this technique in terms of number of sub-band windows, width and overlap of the windows, and their effect on the Doppler signal to noise in a flow phantom. Compared to conventional DOCT, ssDOCT processing has increased flow sensitivity. We demonstrate the effectiveness of ssDOCT in-vivo for intravascular flow detection within ...

      Read Full Article
    4. Miniature forward-imaging B-scan optical coherence tomography probe to guide real-time laser ablation

      Miniature forward-imaging B-scan optical coherence tomography probe to guide real-time laser ablation

      Background and Objective Investigations have shown that pulsed lasers tuned to 6.1 µm in wavelength are capable of ablating ocular and neural tissue with minimal collateral damage. This study investigated whether a miniature B-scan forward-imaging optical coherence tomography (OCT) probe can be combined with the laser to provide real-time visual feedback during laser incisions. Study Design/Methods and Materials A miniature 25-gauge B-scan forward-imaging OCT probe was developed and combined with a 250 µm hollow-glass waveguide to permit delivery of 6.1 µm laser energy. A gelatin mixture and both porcine corneal and retinal tissues were simultaneously imaged and ...

      Read Full Article
    5. PhD Student Position: design, fabrication and control of 2-axis endoscopic MOEMS scanner and implementation in an endomicroscopy microsystem for early diagnosis of cancer FEMTO-ST, Besançon, France

      PhD Student Position: design, fabrication and control of 2-axis endoscopic MOEMS scanner and implementation in an endomicroscopy microsystem for early diagnosis of cancer FEMTO-ST, Besançon, France

      PhD Student Position: design, fabrication and control of 2-axis endoscopic MOEMS scanner and implementation in an endomicroscopy microsystem for early diagnosis of cancer The FEMTO-ST Institute (CNRS unit), associated with the Université de Franche-Comté (UFC), announces the opening of a PhD Student position in design and fabrication of Biophotonic Microsystems. This position, delivering a PhD diploma of UFC, is starting from October 1, 2014. The position is proposed in the frame of a joint collaboration between FEMTO-ST/UFC and Department of Electrical and Computer Engineering/University of Florida (UF), and includes a stage of 18 months at UF, Florida. FEMTO-ST ...

      Read Full Article
    6. CP-OCT sensor guided SMART micro-forceps

      CP-OCT sensor guided SMART micro-forceps

      Even the most stable hands have unintended movements on the order of 50-100 microns within 0-15 Hz. Micro-forceps are one of the frequently used microsurgical tools used to grasp thin layers of tissue during microsurgery. Here, a handheld Smart Micromanipulation Aided Robotic-surgery Tool (SMART) micro-forceps is developed by integrating a fiber-optic common-path optical coherence tomography (CP-OCT) sensor into the micro-forceps. This forceps design could significantly improve performance by canceling unwanted hand tremor during the moment of a grasping. The basic grasping and peeling functions of the micro-forceps are evaluated in dry phantoms and in a biological tissue model.

      Read Full Article
    7. Development of Real-Time Dual-Display Handheld and Bench-Top Hybrid-Mode SD-OCTs

      Development of Real-Time Dual-Display Handheld and Bench-Top Hybrid-Mode SD-OCTs

      Development of a dual-display handheld optical coherence tomography (OCT) system for retina and optic-nerve-head diagnosis beyond the volunteer motion constraints is reported. The developed system is portable and easily movable, containing the compact portable OCT system that includes the handheld probe and computer. Eye posterior chambers were diagnosed using the handheld probe, and the probe could be fixed to the bench-top cradle depending on the volunteers’ physical condition. The images obtained using this handheld probe were displayed in real time on the computer monitor and on a small secondary built-in monitor; the displayed images were saved using the handheld probe ...

      Read Full Article
    8. Scientists reconfirm suitability of Mirrorcle MEMS mirrors for OCT applications

      Scientists reconfirm suitability of Mirrorcle MEMS mirrors for OCT applications

      Scientists reconfirm suitability of Mirrorcle MEMS mirrors for OCT applications Recent publications in peer-reviewed journals have re-confirmed that Mirrorcle MEMS mirror devices are an enabling technology for optical coherence tomography (OCT) imaging applications, Mirrorcle Technologies, Inc. (MTI) informs. The California-based manufacturer of gimbal-less MEMS mirrors reports that multiple recent publications by distinguished research groups show that its devices are being used in the latest advancements of biomedical imaging. Previously, the company announced that two commercial customers had adopted the fast two-axis MEMS mirrors for biomedical imaging, namely Wasatch Photonics (USA) and Santec (Japan). At the same time, the enthusiasm in ...

      Read Full Article
    9. Compact piezoelectric transducer fiber scanning probe for optical coherence tomography

      Compact piezoelectric transducer fiber scanning probe for optical coherence tomography

      We developed a compact, optical fiber scanning piezoelectric transducer (PZT) probe for endoscopic and minimally invasive optical coherence tomography (OCT). Compared with previous forward-mount fiber designs, we present a reverse-mount design that achieves a shorter rigid length. The fiber was mounted at the proximal end of a quadruple PZT tube and scanned inside the hollow PZT tube to reduce the probe length. The fiber resonant frequency was 338 Hz using a 17-mm-long fiber. A 0.9 mm fiber deflection was achieved with a driving amplitude of 35 V. Using a GRIN lens-based optical design with a 1.3 × magnification, a ...

      Read Full Article
    10. Data Encoders For Medical Devices And Related Methods

      Data Encoders For Medical Devices And Related Methods

      In part, the invention relates to systems, methods, and devices that store and retrieve information associated with an imaging probe such as an ultrasound probe, as optical coherence tomography probe, a multimodal probe and other probes. The information mat is stored' relates to one or more measurable properties for a specific imaging probe. Thus, when each probe is manufactured there can be variations in its length, brightness., angular alignment of its constituent elements, and various other probe specific measurements, hi turn, these measurements can be used to calibrate or otherwise use a given probe with a system that collects, stores ...

      Read Full Article
      Mentions: St. Jude Medical
    11. Needle optical coherence elastography for the measurement of microscale mechanical contrast deep within human breast tissues

      Needle optical coherence elastography for the measurement of microscale mechanical contrast deep within human breast tissues

      Optical coherence elastography (OCE) is an emerging imaging technique that probes microscale mechanical contrast in tissues with the potential to differentiate healthy and malignant tissues. However, conventional OCE techniques are limited to imaging the first 1 to 2 mm of tissue in depth. We demonstrate, for the first time, OCE measurements deep within human tissues using needle OCE, extending the potential of OCE as a surgical guidance tool. We use needle OCE to detect tissue interfaces based on mechanical contrast in both normal and malignant breast tissues in freshly excised human mastectomy samples, as validated against histopathology. Further, we demonstrate ...

      Read Full Article
    12. Handheld ultrahigh speed swept source optical coherence tomography instrument using a MEMS scanning mirror

      Handheld ultrahigh speed swept source optical coherence tomography instrument using a MEMS scanning mirror

      We developed an ultrahigh speed, handheld swept source optical coherence tomography (SS-OCT) ophthalmic instrument using a 2D MEMS mirror. A vertical cavity surface-emitting laser (VCSEL) operating at 1060 nm center wavelength yielded a 350 kHz axial scan rate and 10 µm axial resolution in tissue. The long coherence length of the VCSEL enabled a 3.08 mm imaging range with minimal sensitivity roll-off in tissue. Two different designs with identical optical components were tested to evaluate handheld OCT ergonomics. An iris camera aided in alignment of the OCT beam through the pupil and a manual fixation light selected the imaging ...

      Read Full Article
    13. Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode

      Early Detection of Blinding Eye Disease Could be as Easy as Scanning a Barcode

      New hand-held optical device to catch early signs of retinal disease WASHINGTON, Dec. 20, 2013—A new optical device puts the power to detect eye disease in the palm of a hand. The tool—about the size of a hand-held video camera—scans a patient’s entire retina in seconds and could aid primary care physicians in the early detection of a host of retinal diseases including diabetic retinopathy, glaucoma and macular degeneration. Researchers at the Massachusetts Institute of Technology (MIT) describe their new ophthalmic-screening instrument in a paper published today in the open-access journal Biomedical Optics Express , published by ...

      Read Full Article
    14. A large-scan-angle piezoelectric MEMS optical scanner actuated by a Nb-doped PZT thin film

      A large-scan-angle piezoelectric MEMS optical scanner actuated by a Nb-doped PZT thin film

      Resonant 1D microelectromechanical systems (MEMS) optical scanners actuated by piezoelectric unimorph actuators with a Nb-doped lead zirconate titanate (PNZT) thin film were developed for endoscopic optical coherence tomography (OCT) application. The MEMS scanners were designed as the resonance frequency was less than 125 Hz to obtain enough pixels per frame in OCT images. The device size was within 3.4 mm × 2.5 mm, which is compact enough to be installed in a side-imaging probe with 4 mm inner diameter. The fabrication process started with a silicon-on-insulator wafer, followed by PNZT deposition by the Rf sputtering and Si bulk micromachining ...

      Read Full Article
    15. Imaging deep skeletal muscle structure using a high-sensitivity ultrathin side-viewing optical coherence tomography needle probe

      Imaging deep skeletal muscle structure using a high-sensitivity ultrathin side-viewing optical coherence tomography needle probe

      We have developed an extremely miniaturized optical coherence tomography (OCT) needle probe (outer diameter 310 µm) with high sensitivity (108 dB) to enable minimally invasive imaging of cellular structure deep within skeletal muscle. Three-dimensional volumetric images were acquired from ex vivo mouse tissue, examining both healthy and pathological dystrophic muscle. Individual myofibers were visualized as striations in the images. Degradation of cellular structure in necrotic regions was seen as a loss of these striations. Tendon and connective tissue were also visualized. The observed structures were validated against co-registered hematoxylin and eosin (H&E) histology sections. These images of internal cellular ...

      Read Full Article
    16. Development of novel imaging probe for optical∕acoustic radiation imaging (OARI)

      Development of novel imaging probe for optical∕acoustic radiation imaging (OARI)

      Purpose: Optical/acoustic radiation imaging (OARI) is a novel imaging modality being developed to interrogate the optical and mechanical properties of soft tissues. OARI uses acoustic radiation force to generate displacement in soft tissue. Optical images before and after the application of the force are used to generate displacement maps that provide information about the mechanical properties of the tissue under interrogation. Since the images are optical images, they also represent the optical properties of the tissue as well. In this paper, the authors present the first imaging probe that uses acoustic radiation force in conjunction with optical coherence tomography ...

      Read Full Article
    17. Apparatus for biomedical imaging

      Apparatus for biomedical imaging

      A system that incorporates teachings of the present disclosure may include, for example, a method involving capturing spectral interference from an optical coherence tomography imaging probe comprising a micro-electro-mechanical system (MEMS) scanning mirror, and a partial reflector for supplying images to an image sensor. Additional embodiments are disclosed.

      Read Full Article
    18. Feature Of The Week 11/24/13 : Miniature OCT/IVUS probe for automatically co-registered three-dimensional intracoronary imaging with real-time display

      Feature Of The Week 11/24/13 : Miniature OCT/IVUS probe for automatically co-registered three-dimensional intracoronary imaging with real-time display

      Combined use of intravascular ultrasound (IVUS) and optical coherence tomography (OCT) holds the potential of combining the strengths of both imaging modalities and improving the diagnostic accuracy of atherosclerotic plaque vulnerability. In this manuscript, we reported a co-registered intracoronary OCT-IVUS system and catheter with real-time imaging and polar-coordinate displaying capability, well-suited for clinical utilization in guiding interventional cardiologists. With an eventual goal of clinical use in humans, this novel catheter design and modified software are poised to strengthen the ability to diagnose vulnerable plaques in patients in real-time. We upgraded our old designs in the following aspects. 1) This novel ...

      Read Full Article
    19. Ball Lens Fiber Optic Sensor based Smart Handheld Microsurgical Instrument

      Ball Lens Fiber Optic Sensor based Smart Handheld Microsurgical Instrument

      During freehand performance of vitreoretinal microsurgery the surgeon must perform precise and stable maneuvers that achieve surgical objectives and avoid surgical risk. Here, we present an improved smart handheld microsurgical tool which is based on a ball lens fiber optic sensor that utilizes common path swept source optical coherence tomography. Improvements include incorporation of a ball lens single mode fiber optic probe that increases the working angle of the tool to greater than 45 degrees; and increases the magnitude of the distance sensing signal through water. Also presented is a cutting function with an improved ergonomic design

      Read Full Article
    20. Asymmetric double-clad fiber couplers for endoscopy

      Asymmetric double-clad fiber couplers for endoscopy

      We present an asymmetric double-clad fiber coupler (A-DCFC) exploiting a disparity in fiber etendues to exceed the equipartition limit ( ≤ 50 % extraction of inner cladding multi-mode light). The A-DCFC is fabricated using two commercially available fibers and a custom fusion-tapering setup to achieve > 70 % extraction of multi-mode inner cladding light without affecting ( > 95 % transmission) single-mode light propagation in the core. Imaging with the A-DCFC is demonstrated in a spectrally encoded imaging setup using a weakly backscattering biological sample. Other applications include the combination of optical coherence tomography with weak fluorescent or Raman scattering signals

      Read Full Article
    21. Feature Of The Week 10/13/13: Tsinghua University Demonstrates a Tiny OCT Endoscopic Probe Using a Hollow Ultrasonic Motor

      Feature Of The Week 10/13/13: Tsinghua University Demonstrates a Tiny OCT Endoscopic Probe Using a Hollow Ultrasonic Motor

      Optical coherence tomography (OCT) is an emerging modality for obtaining cross-sectional images. Due to limitation of the light penetration, small and high resolution probes for endoscopic OCT have been regarded as powerful tools in examining internal organs. Among them, circumferential probes are utilized extensively for imaging within hollow tissues, such as arteries, esophagus, and colon. In recent years, distal scanning is of high interest, as the whole fiber remains stationary in this case. The twisting and nonuniformity in the conventional proximal scanning are avoided. However, some problems emerge such as the wire-shadow effect and the relative large size of the ...

      Read Full Article
    22. Improvement of optical coherence tomography using active handheld micromanipulator in vitreoretinal surgery

      Improvement of optical coherence tomography using active handheld micromanipulator in vitreoretinal surgery

      An active handheld micromanipulator has been developed to cancel hand tremor during microsurgery. The micromanipulator is also applicable in optical coherence tomography to improve the quality of scanning and minimize surgical risks during the scans. The manipulator can maneuver the tool tip with six degrees of freedom within a cylindrical workspace 4 mm in diameter and 4 mm high. The imaging system is equipped with a 25-gauge Fourier-domain common-path OCT probe. This paper introduces the handheld OCT imaging system and techniques involved and presents stabilized OCT images of A-mode and M-mode scans in air and live rabbit eyes. We show ...

      Read Full Article
    23. Dynamic focus-tracking MEMS scanning micromirror with low actuation voltages for endoscopic imaging

      Dynamic focus-tracking MEMS scanning micromirror with low actuation voltages for endoscopic imaging

      We demonstrate a 3-D scanning micromirror device that combines 2-D beam scanning with focus control in the same device using micro-electro-mechanical-systems (MEMS) technology. 2-D beam scanning is achieved with a biaxial gimbal structure and focus control is obtained with a deformable mirror membrane surface. The micromirror with 800 micrometer diameter is designed to be sufficiently compact and efficient so that it can be incorporated into an endoscopic imaging probe in the future. The design, fabrication and characterization of the device are described in this paper. Using the focus-tracking MEMS scanning mirror, we achieved an optical scanning range of >16 degrees ...

      Read Full Article
    1-24 of 357 1 2 3 4 ... 13 14 15 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources, Velocimetry
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (1 articles) Sunnybrook Health Sciences Centre
    2. (1 articles) Vanderbilt University
    3. (1 articles) Ryerson University
    4. (1 articles) Seoul National University
    5. (1 articles) University of Toronto
  4. People in the News

    1. (1 articles) Victor X. D. Yang
    2. (1 articles) Stephen Lam
  5. OCT Companies in the News

    1. (1 articles) Bioptigen