1. Articles in category: Probes

    1-24 of 493 1 2 3 4 ... 19 20 21 »
    1. In-line optical fiber metallic mirror reflector for monolithic common path optical coherence tomography probes

      In-line optical fiber metallic mirror reflector for monolithic common path optical coherence tomography probes

      Background and Objectives Endoscopic optical coherence tomography probes suffer from various artifacts due to dispersion imbalance and polarization mismatch between reference and sample arm light. Such artifacts can be minimized using a common path approach. In this work, we demonstrate a miniaturized common path probe for optical coherence tomography using an inline fiber mirror. Materials and Methods A common path optical fiber probe suitable for performing high-resolution endoscopic optical coherence tomography imaging was developed. To achieve common path functionality, an inline fiber mirror was fabricated using a thin gold layer. A commercially available swept source engine was used to test ...

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    2. Systems, methods and apparatuses for real-time anastomosis guidance and surgical evaluation using optical coherence tomography

      Systems, methods and apparatuses for real-time anastomosis guidance and surgical evaluation using optical coherence tomography

      A surgical evaluation and guidance system for use in extravacular evaluation and guidance of fluid vessel surgeries, includes an optical coherence tomography engine; a vessel probe optically coupled to the optical coherence tomography engine; and a signal processing and display system adapted to communicate with the optical coherence tomography engine to receive imaging signals therefrom. An optical coherence tomography vessel probe for use in extravacular evaluation and guidance of fluid vessel surgeries, includes a probe body having a proximal end and a distal end; an optical relay system disposed within the probe body; and a vessel adapter at least one ...

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    3. Anticipating, measuring, and minimizing MEMS mirror scan error to improve laser scanning microscopy's speed and accuracy

      Anticipating, measuring, and minimizing MEMS mirror scan error to improve laser scanning microscopy's speed and accuracy

      We describe a method to speed up m icro e lectro m echanical s ystem (MEMS) mirror scanning by > 20x, while also improving scan accuracy. We use Landweber deconvolution to determine an input voltage which would produce a desired output, based on the measured MEMS impulse response. Since the MEMS is weakly nonlinear, the observed behavior deviates from expectations, and we iteratively improve our input to minimize this deviation. This allows customizable MEMS angle vs. time with <1% deviation from the desired scan pattern. We demonstrate our technique by optimizing a point scanning microscope’s raster patterns to image mammal ...

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    4. New Digital Servo Driver Improves Speed and Precision for Laser Beam Steering

      New Digital Servo Driver Improves Speed and Precision for Laser Beam Steering

      ambridge Technology, a business unit of Novanta Corporation ("Novanta"), announced today the launch of the DC3000 Plus, a new digital servo driver, adding to its product family of components and scan heads for laser beam steering. The DC3000 Plus builds on the success of its predecessor, the DC3000, which applies digital state space controller technology to optimize speed in laser marking applications. With increased drive current and improved thermal management, the DC3000 Plus now offers higher marking speed and it accurately drives larger mirrors faster. These improvements expand the product line's capabilities in laser converting, micromachining, high power welding ...

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    5. Integrated optical coherence analysis system

      Integrated optical coherence analysis system

      Optical coherence tomography (OCT) probe and system designs are disclosed that minimize the effects of mechanical movement and strain to the probe to the OCT analysis. It also concerns optical designs that are robust against noise from the OCT laser source. Also integrated OCT system-probes are included that yield compact and robust electro-opto-mechanical systems along with polarization sensitive OCT systems.

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    6. Endoscopic optical coherence tomography with a focus-adjustable probe

      Endoscopic optical coherence tomography with a focus-adjustable probe

      We present a focus-adjustable endoscopic probe for optical coherence tomography (OCT), which is able to acquire images with different focal planes and overcome depth-of-focus limitations by image fusing. The use of a two-way shape-memory-alloy spring enables the probe to adjust working distance over 1.5 mm, providing a large scanning range with high resolution and no sensitivity loss. Equipped with a homemade hollow-core ultrasonic motor, the probe is capable of performing an unobstructed 360 deg field-of-view distal scanning. Both the axial resolution and the best lateral resolution are ∼ 4    μm ∼4  μm , with a sensitivity of 100.3 dB. Spectral-domain ...

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    7. Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

      Endoscopic forward-viewing optical coherence tomography and angiography with MHz swept source

      Endoscopic optical coherence tomography (OCT) instruments are mostly side viewing and rely on at least one proximal scan, thus limiting accuracy of volumetric imaging and en face visualization. Previous forward-viewing OCT devices had limited axial scan speeds. We report a forward-viewing fiber scanning 3D-OCT probe with 900 μm field of view and 5 μm transverse resolution, imaging at 1 MHz axial scan rate in the human gastrointestinal tract. The probe is 3.3 mm diameter and 20 mm rigid length, thus enabling passage through the endoscopic channel. The scanner has 1.8 kHz resonant frequency, and each volumetric acquisition takes ...

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    8. Lens-free all-fiber probe with an optimized output beam for optical coherence tomography

      Lens-free all-fiber probe with an optimized output beam for optical coherence tomography

      A high-efficiency lensless all-fiber probe for optical coherence tomography (OCT) is presented. The probe is composed of a segment of large-core multimode fiber (MMF), a segment of tapered MMF, and a length of single-mode fiber (SMF). A controllable output beam can be designed by a simple adjustment of its probe structure parameters (PSPs), instead of the selection of fibers with different optical parameters. A side-view probe with a diameter of 340 μm and a rigid length of 6.37 mm was fabricated, which provides an effective imaging range of ∼ 0.6    mm ∼0.6  mm with a full width at ...

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    9. Imaging probes and associated devices, systems, and methods utilizing electrostatic actuators

      Imaging probes and associated devices, systems, and methods utilizing electrostatic actuators

      Devices, systems, and methods that utilize at least one charged electrode to impart motion to an optical fiber positioned within an imaging probe by an electrostatic force are provided. In some embodiments, an ophthalmic imaging probe can include a handle; a cannula coupled to the handle; an optical fiber positioned at least partially within the handle and the cannula, the optical fiber configured to receive an imaging light from an imaging light source and guide the imaging light to an optical element positioned within the cannula; and an actuator system configured to impart motion to the optical fiber, the actuator ...

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    10. OCT probe with bowing flexor

      OCT probe with bowing flexor

      An OCT probe includes a cannula and includes a selectively displaceable light-carrying optical fiber disposed within the cannula. The optical fiber may be arranged to emit light from a distal end thereof. A flexor may be bent to divide the flexor into a first segment and a second segment extending along a lumen of the cannula. The first segment may be coupled to the optical fiber. A driver may be configured to push or pull the second segment in the axial direction to elastically bow the second segment and laterally displace the optical fiber to perform an OCT scan.

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    11. Optical probe for optical coherence tomography and manufacturing method therefor

      Optical probe for optical coherence tomography and manufacturing method therefor

      To provide an optical probe for OCT and a method of manufacturing the optical probe that can reduce reflected light generated at a boundary portion between an optical fiber and a lensed fiber. An optical probe for OCT includes an optical fiber that transmits irradiation light and back-scattered light and a lensed fiber that is fusion spliced to an end face of the optical fiber, that emits irradiation light toward the inside of a living body while collimating the irradiation light, and that collects and guides back-scattered light to the end face of the optical fiber. A refractive index adjusting ...

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    12. Non-invasive diagnostic system and its opto-mechanical probe for combining confocal Raman spectroscopy and optical coherence tomography

      Non-invasive diagnostic system and its opto-mechanical probe for combining confocal Raman spectroscopy and optical coherence tomography

      Non-invasive optical diagnostic methods allow important information about studied systems to be obtained in a non-destructive way. Complete diagnosis requires information about the chemical composition as well as the morphological structure of a sample. We report on the development of an opto-mechanical probe that combines Raman spectroscopy (RS) and optical coherence tomography (OCT), two methods that provide all the crucial information needed for a non-invasive diagnosis. The aim of this paper is to introduce the technical design, construction and optimization of a dual opto-mechanical probe combining two in-house developed devices for confocal RS and OCT. The unique benefit of the ...

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    13. Imaging collector channel entrance with a new intraocular micro-probe swept-source optical coherence tomography

      Imaging collector channel entrance with a new intraocular micro-probe swept-source optical coherence tomography

      Purpose To describe the use of a newly developed side-viewing catheter probe to provide the cross-sectional images of collector channel entrance (CCE), achieved by swept-source optical coherence tomography (SS-OCT). Methods A side-viewing SS-OCT catheter probe was developed that has a core probe diameter of 0.15 mm and an outer diameter of 0.25 mm, for the purpose of imaging CCEs within eye globe. Cadaver eyes harvested from swine and human were used to demonstrate its feasibility. For porcine eyes, the probe imaged the CCE by accessing the region of the aqueous plexus (AP) as well as along the inner ...

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    14. Endoscopic biopsy apparatus, system and method

      Endoscopic biopsy apparatus, system and method

      Exemplary embodiments of apparatus, method and system for determining a position on or in a biological tissue can be provided. For example, using such exemplary embodiment, it is possible to control the focus of an optical imaging probe. In another exemplary embodiment, it is possible to implement a marking apparatus together with or into an optical imaging probe. According to one exemplary embodiment, it is possible (using one or more arrangements) to receive information associated with at least one image of at least one portion of the biological tissue obtained using an optical imaging technique. Further, it is possible to ...

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    15. OCT probes and OCT optical probe component for use therein

      OCT probes and OCT optical probe component for use therein

      An OCT optical probe component comprising: A rod having a first end and a second end, a lens situated proximate to the second end of the rod, the lens having a surface with an inner zone a, and an outer zone b, wherein the inner zone a is associated with the focal length fla, and said outer zone b is associated with the focal length flb, such that optical probe component is multi-focal, the optical probe capable of imaging at multiple image planes, via the lens of an object adjacent to the first end of the rod, wherein the at ...

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      Mentions: Corning
    16. Miniature multimodal endoscopic probe based on double-clad fiber

      Miniature multimodal endoscopic probe based on double-clad fiber

      Optical coherence tomography (OCT) can obtain light scattering properties with a high resolution, while photoacoustic imaging (PAI) is ideal for mapping optical absorbers in biological tissues, and ultrasound (US) could penetrate deeply into tissues and provide elastically structural information. It is attractive and challenging to integrate these three imaging modalities into a miniature probe, through which, both optical absorption and scattering information of tissues as well as deep-tissue structure can be obtained. Here, we present a novel side-view probe integrating PAI, OCT and US imaging based on double-clad fiber which is used as a common optical path for PAI (light ...

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    17. Single lens system for forward-viewing navigation and scanning side-viewing optical coherence tomography

      Single lens system for forward-viewing navigation and scanning side-viewing optical coherence tomography

      The optical design for a dual modality endoscope based on piezo scanning fiber technology is presented including a novel technique to combine forward-viewing navigation and side viewing OCT. Potential applications include navigating body lumens such as the fallopian tube, biliary ducts and cardiovascular system. A custom cover plate provides a rotationally symmetric double reflection of the OCT beam to deviate and focus the OCT beam out the side of the endoscope for cross-sectional imaging of the tubal lumen. Considerations in the choice of the scanning fiber are explored and a new technique to increase the divergence angle of the scanning ...

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    18. In vivo 3D imaging of the human tympanic membrane using a wide-field diagonal-scanning optical coherence tomography probe

      In vivo 3D imaging of the human tympanic membrane using a wide-field diagonal-scanning optical coherence tomography probe

      A wide-field optical coherence tomography (OCT) probe was developed that adapts a diagonal-scanning scheme for three-dimensional (3D) in vivo imaging of the human tympanic membrane. The probe consists of a relay lens to enhance the lateral scanning range up to 7 mm. Motion artifacts that occur with the use of handheld probes were found to be decreased owing to the diagonal-scanning pattern, which crosses the center of the sample to facilitate entire 3D scans. 3D images could be constructed from a small number of two-dimensional OCT images acquired using the diagonal-scanning technique. To demonstrate the usefulness and performance of the ...

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    19. Design and optimization of a miniaturized imaging probe for simultaneous endomicroscopy and optical coherence tomography

      Design and optimization of a miniaturized imaging probe for simultaneous endomicroscopy and optical coherence tomography

      A highly-integrated MEMS-based bimodal probe design with integrated piezoelectric fiber scanner for simultaneous endomicroscopy and optical coherence tomography (OCT) is presented. The two modalities rely on spectrally-separated optical paths that run partially in parallel through a micro-optical bench system, which has dimensions of only 13 x 2 x 3mm 3 (l x w x h). An integrated tubular piezoelectric fiber scanner is used to perform en face scanning required for three dimensional OCT measurements. This scanning engine has an outer diameter of 0.9mm and a length of 9mm, and features custom fabricated 10 μm thick polyimide flexible interconnect lines ...

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    20. Surgical devices and methods utilizing optical coherence tomography (OCT) to monitor and control tissue sealing

      Surgical devices and methods utilizing optical coherence tomography (OCT) to monitor and control tissue sealing

      Surgical devices and methods for utilizing optical coherence tomography (OCT) to monitor and control tissue sealing are disclosed. The surgical device includes an end effector assembly that includes first and second jaw members that are movable between a first, spaced-apart position and a second proximate position. An OCT system, at least a portion of which is incorporated into the end effector assembly, is configured to sense properties of the tissue, e.g., the structural density of the tissue, disposed between the first and second jaw members. A tissue-sealing energy source may be disposed within at least one of the jaw ...

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    21. Probe for optical imaging

      Probe for optical imaging

      A probe for a three-dimensional (3D) scanning optical imaging which prevents rotational irregularity, axial runout, friction, rotation transmission delays of a rotational part by reducing occurrences of rotation transmission delays, torque loss, and the like, and can perform scanning of a certain length in an axial direction and obtain a three-dimensional observation image, in a probe for OCT image diagnosis. A fixed side optical fiber that transmits light between a tip side and a rear side of a probe and is non-rotatably disposed, a first optical path conversion means that rotates to emit a light ray in a substantially radial ...

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    22. Flexible, high-resolution micro-optical coherence tomography endobronchial probe toward in vivo imaging of cilia

      Flexible, high-resolution micro-optical coherence tomography endobronchial probe toward in vivo imaging of cilia

      We report the design and fabrication of a flexible, longitudinally scanning high-resolution micro-optical coherence tomography (μOCT) endobronchial probe, optimized for micro-anatomical imaging in airways. The 2.4 mm diameter and flexibility of the probe allows it to be inserted into the instrument channel of a standard bronchoscope, enabling real-time video guidance of probe placement. To generate a depth-of-focus enhancing annular beam, we utilized a new fabrication method, whereby a hollow glass ferrule was angle-polished and gold-coated to produce an elongated annular reflector. We present validation data that verifies the preservation of linear scanning, despite the use of flexible materials. When ...

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    1-24 of 493 1 2 3 4 ... 19 20 21 »
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    1. (1 articles) Massachusetts General Hospital
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    1. (1 articles) Guillermo J. Tearney
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