Popular Articles
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OCT Companies in the News
(12 articles) Axsun Technologies
(2 articles) Praevium Research
(2 articles) Carl Zeiss Meditec
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Organizations in the News
(12 articles) Ludwig Maximilians Universität München
(10 articles) Massachusetts Institute of Technology
(7 articles) Ryerson University
(7 articles) National Research Council Canada
(7 articles) Harvard University
(7 articles) University of Toronto
(5 articles) Kitasato University
(4 articles) Massachusetts General Hospital
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Ultrahigh-speed volumetric ophthalmic OCT imaging at 800nm and 1050nm
Explore Article SPIE Digital Library (Mar 2 2010) Ophthalmology , Tunable Sources
The performance and imaging characteristics of ultrahigh speed ophthalmic optical coherence tomography (OCT) are investigated. In vivo imaging results are obtained at 850nm and 1050nm using different configurations of spectral and swept source / Fourier domain OCT. A spectral / Fourier domain instrument using a high speed CMOS linescan camera with SLD light source centered at 850nm achieves speeds of ~91,000 axial scans per second with ~3µm axial resolution in tissue. A spectral / Fourier domain instrument using an InGaAs linescan camera with SLD light source centered at 1050nm achieves ~47,000 axial scans per second with ~7µm resolution in tissue. ...
Comment on Article Mentions: Massachusetts Institute of Technology Thorlabs Iwona Gorczyńska
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Simultaneous 6-channel optical coherence tomography using a high-power telescope-less polygon-based swept laser in dual amplifier configuration
Explore Article SPIE Digital Library (Feb 28 2010) Tunable Sources
Multichannel optical coherence tomography (MOCT) imaging is demonstrated using a high-power wavelength-swept laser source. The main benefit of MOCT is faster image acquisition rates without a corresponding increase in the laser tuning speed. The wavelength-swept laser was constructed using a compact telescope-less polygon-based filter in Littman arrangement. High output power, necessary for MOCT, was achieved by incorporating two serial semiconductor optical amplifiers in a ring laser cavity in Fourier domain mode-locked configuration. The laser has a measured wavelength tuning range of 111 nm centered at 1329 nm, coherence length of 5.5 mm, and total average output power of 131 mW ...
Comment on Article Mentions: Ontario Cancer Institute University of Toronto Victor X. D. Yang
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Multichannel optical coherence tomography using a high-power telescope-less polygon-based swept laser in dual-amplifier configuration
Explore Article Optical Coherence Tomography News (Feb 28 2010) Tunable Sources
Feature Of The Week 2/28/10: Researchers at the University of Toronto, Ontario Cancer Institute and Ryerson University have been active advancing Optical Coherence Tomography in several areas including application of Doppler OCT and advancing the underlying technology to expand and improve the applications and capability of OCT
Comment on Article Mentions: Ontario Cancer Institute University of Toronto I. Alex Vitkin
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Compact ultrafast reflective Fabry-Perot tunable lasers for OCT imaging applications
Explore Article SPIE Digital Library (Feb 22 2010) Tunable Sources
We demonstrate a novel reflective Fabry-Perot tunable laser (RFPTL) for high speed swept-source optical coherence tomography (OCT) imaging applications. This external cavity semiconductor laser uses a silicon MEMS tunable Fabry- Perot filter in a novel reflective mode of operation. The laser is packaged in a compact 25x15 mm fiber-pigtailed butterfly package. Lasers at 1060 and 1300 nm wavelengths have been demonstrated with tuning ranges up to 140 nm, fast scan rates of 100 kHz, and coherence lengths greater than 13 mm. We also describe OCT imaging with these lasers. RFPTL lasers with 1-2 µm wavelengths and tuning ranges of 250 ...
Comment on Article Mentions: Axsun Technologies Dale Flanders
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MEMS scanner based swept source laser for optical coherence tomography
Explore Article SPIE Digital Library (Feb 19 2010) Tunable Sources
We developed a swept source laser using a micro electro mechanical systems (MEMS) scanner mirror, and demonstrated optical coherence tomography. To enable both the wide tuning wavelength range and high scanning frequency, we introduced 2-degree-of-freedom(2-DOF) MEMS scanner mirror. A tunable optical filter is composed of a MEMS scanner mirror and a diffraction grating which is arranged in Littrow configuration. We built a swept source laser which has a wavelength range of 143 nm, center wavelength of 1304 nm, and a peak power of 16 mW. OCT measurements are performed at a rate of 17.9 kHz and doubled 35.9 kHz at ...
Comment on Article Mentions: Santec Changho Chong
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Tunable semiconductor laser based on interaction between strongly mismatched Fabry-Perot interferometer and waveguide modes
Explore Article SPIE Digital Library (Feb 19 2010) Tunable Sources
The method of spectral selection, based on small optical connection between tilted short Fabry-Perot interferometer and semiconductor optical amplifier has been proposed. It was shown, that short Fabry-Perot interferometer under certain inclination reflects back in narrowband lines, typical for transmitted spectrum. This effect has been used for creation swept semiconductor laser with wavelength tuning range 25 nm at central wavelength 1290 nm and coherence length 8 mm.
Comment on Article Mentions: Grigory V. Gelikonov Russian Academy of Sciences Valentin M. Gelikonov
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High-speed concatenation of frequency ramps using sampled grating distributed Bragg reflector laser diode sources for OCT resolution enhancement
Explore Article SPIE Digital Library (Feb 19 2010) Tunable Sources
Wavelength tunable sampled grating distributed Bragg reflector (SG-DBR) lasers used for telecommunications applications have previously demonstrated the ability for linear frequency ramps covering the entire tuning range of the laser at 100 kHz repetition rates1. An individual SG-DBR laser has a typical tuning range of 50 nm. The InGaAs/InP material system often used with SG-DBR lasers allows for design variations that cover the 1250 to 1650 nm wavelength range. This paper addresses the possibility of concatenating the outputs of tunable SGDBR lasers covering adjacent wavelength ranges for enhancing the resolution of OCT measurements. This laser concatenation method is demonstrated by ...
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Developing dual core ytterbium doped fiber ring laser in Fourier domain mode locked operation for swept-source optical coherence tomography
Explore Article SPIE Digital Library (Feb 17 2010) Tunable Sources
We demonstrate high efficiency and wide bandwidth gain in a Ytterbium doped fiber amplifier. The highpowered amplifier has potential applications for use with a swept-source fiber ring laser in multi-channel optical coherence tomography (OCT) system. The ring cavity design includes a 976nm pumped dual core Yb doped fiber as the gain medium, where a rotating polygon mirror is used as a wavelength-sweeping filter for this source. The amplified spontaneous emission (ASE) had a spectral bandwidth of 1037-1145nm at -60dBm, where a tunable lasing bandwidth of the ring cavity ranged from 1057-1115nm. The highest output power, for both the ASE and ...
Comment on Article Mentions: University of Toronto Sunnybrook Health Sciences Centre Victor X. D. Yang
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Cascaded Raman fiber laser in Fourier domain mode lock operation
Explore Article SPIE Digital Library (Feb 17 2010) Tunable Sources
In this study, a cascaded Raman fiber laser in Fourier domain mode lock operation (FDML) is presented. This laser utilizes a Ytterbium doped twin core pump laser source at 1109 nm. The pump light is directed to a cascaded Raman cavity, which consists of multiple cascaded fiber Bragg grating pairs and 3.86 km of dispersion compensation fiber, which provides Raman gain. The output wavelength of a cascaded Raman laser is determined by the Stoke’s shift (≈ 60 to 70 nm in optical fiber) and the pump laser wavelength. The power build up in the cascaded Raman cavity and shift to ...
Comment on Article Mentions: Victor X. D. Yang Beau A. Standish University of Toronto
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Improvement in dynamic range limitation of swept source optical coherence tomography by true logarithmic amplification
Explore Article opticsinfobase.org (Feb 10 2010) Tunable Sources
We previously demonstrated, with both theoretical and experimental studies, the dynamic range limitation with spectral domain optical coherence tomography (OCT) relative to time domain OCT. A significant portion of this limitation was due to the difference of analog/digital conversion. In this paper, a new method of true logarithmic amplification is discussed theoretically and tested experimentally to increase the dynamic range of a swept source OCT. With the current experimental setup, an increase of the dynamic range by about 6 dB was obtained.
Comment on Article Mentions: Mark E. Brezinski Brigham and Women’s Hospital Harvard University
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Coupled cavity InGaAsP/InP laser for synthetic optical coherence tomography and other applications
Explore Article IEEE Xplore (Feb 4 2010) Tunable Sources
The authors describe widely tunable coupled cavity semiconductor lasers with sub-microsecond switching times between modes over the operating range of ˜100 nm. With appropriate modulation of injection currents and time averaging of the output, these devices provide short coherence lengths and can be an excellent source for synthesised optical coherence tomography (OCT). The depth resolution was found to be ˜15 mm for a 100 nm wavelength tuning range centred at 1580 nm. High-output power and brightness together with a short coherence length confers on these asymmetric multiple quantum well (AMQW) C3 laser some advantages over conventional sources for OCT. Also, ...
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Real-time and high-performance calibration method for high-speed swept-source optical coherence tomography
Explore Article SPIE Digital Library (Jan 28 2010) Tunable Sources
For high-speed swept-source optical coherence tomography (SS-OCT), the real-time calibration process to convert the OCT signal to wave number space is highly essential. A novel calibration process/algorithm using a genetic algorithm and precise interpolation is developed. This algorithm is embedded and validated in a SS-OCT system with 16-kHz A-scan rate. The performance of the new algorithm is evaluated by measuring point spread functions at two distinct locations in the entire imaging range. The data is compared to the same system but embedded with a regular calibration algorithm, which demonstrates about 20% improvement in the axial resolution. The steady improvement at ...
Comment on Article Mentions: Mark E. Brezinski Harvard University Brigham and Women’s Hospital
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Wavelength-swept spectral and pulse shaping utilizing hybrid Fourier domain modelocking by fiber optical parametric and erbium-doped fiber amplifiers
Explore Article opticsinfobase.org (Jan 15 2010) Tunable Sources
We report the first Fourier domain modelocked (FDML) laser constructed using optical parametric amplifier (OPA) in conjunction with an erbium-doped fiber amplifier (EDFA), centered at ~1555nm, to the best of our knowledge. We utilize a one-pump OPA and a C-band EDFA in serial configuration with a tunable Fabry-Perot interferometer to generate a hybrid FDML spectrum. Results demonstrate a substantially better spectral shape, output power and stability than individual configurations, with decreased sensitivity to polarization changes. We believe this technique has the potential to enable several amplifiers to complement individual deficiencies resulting in improved spectral shapes and power generation for imaging ...
Comment on Article Mentions: University of Toronto Victor X. D. Yang Beau A. Standish
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High axial resolution swept source for optical coherence tomography
Explore Article IEEE Xplore (Jan 6 2010) Tunable Sources
A high resolution simple swept source for OCT measurements is presented. Low skew frequency domain triggering via electronic processing allowed resolutions of one FFT bin for a single reflection. The high resolution capability was demonstrated in a system containing ~10 mm spaced interfaces.
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Fourier Domain Mode Locking (FDML): Wavelength Swept Lasers for Ultrahigh Speed Optical Coherence Tomography
Explore Article SpringerLink Home (Jan 4 2010) Tunable Sources
Optical coherence tomography (OCT) is a novel, depth resolved biomedical imaging technique, providing highresolution, cross-sectional and three-dimensional images of tissue microstructure. The application of OCT systems based on rapidly wavelength swept, narrow band light sources, referred to as “swept source OCT” or “optical frequency domain imaging”, offers several potential advantages compared to high speed OCT systems based on fast spectrometers. The advent of Fourier domain mode locked (FDML) lasers as light sources for swept source OCT enabled high imaging speeds of up to 370.000 lines or A-scans per second, combined with good phase stability and long ranging depths. In this ...Comment on Article Mentions: Ludwig Maximilians Universität München Robert A. Huber








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Great video Jim!
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Dear Prof. Dr. Gary S. Mintz, You are an extraordinary expert in imaging, an intelligence ...
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