1. Articles in category: Urology

    169-181 of 181 « 1 2 3 4 5 6 7 8
    1. Interstitial Doppler Optical Coherence Tomography as a Local Tumor Necrosis Predictor in Photodynamic Therapy of Prostatic Carcinoma: An In vivo Study

      We have tested the feasibility of real-time localized blood flow measurements, obtained with interstitial (IS) Doppler optical coherence tomography (DOCT), to predict photodynamic therapy (PDT)-induced tumor necrosis deep within solid Dunning rat prostate tumors. IS-DOCT was used to quantify the PDT-induced microvascular shutdown rate in s.c. Dunning prostate tumors (n = 28). Photofrin (12.5 mg/kg) was administered 20 to 24 hours before tumor irradiation, with 635 nm surface irradiance of 8 to 133 mWcm–2 for 25 minutes. High frequency ultrasound and calipers were used to measure the thickness of the skin covering the tumor and the ...
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    2. Intravesical real-time imaging and staging of bladder cancer: Use of optical coherence tomography

      In this retrospective study, the authors have assessed the application of optical coherence tomography (OCT) as an adjunct to conventional cystoscopy in the endoscopic evaluation of bladder tumors. From December 2005 to April 2007, 32 patients (25 men and seven women with median age of 59 years), majority of whom were known or newly diagnosed cases of bladder cancer, underwent OCT in addition to conventional rigid cystoscopy by a single surgeon. The US FDA-approved Niris Imaging System was used to acquire OCT images. The images of normal and suspicious areas were obtained prior to biopsy/resection using a flexible fiber ...
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      Mentions: Imalux Niris
    3. Imaging in Oncological Urology (Book)

      Imaging in Oncological Urology (Book)
      Prostate cancer is now the primary malignancy in men, while bladder and renal cancer are not far behind. This hugely important book details significant changes in imaging in oncological conditions related to the bladder, prostate and kidneys. The focus is on oncology in urology, mainly Ultrasound and MRI, with organ-oriented topics. The latest technologies on imaging are included to better identify carcinomatous lesions and lymph node metastases. Each chapter includes a section that outlines the optimal imaging approach, providing an algorithm for imaging per disease entity, and according to the evidence-based chronological and diagnostic follow-up. What makes this book so ...
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    4. High-resolution imaging diagnosis and staging of bladder cancer: comparison between optical coherence tomography and high-frequency ultrasound

      Zhijia Yuan, Zhenguo Wang, Rubin Pan et al. A comparative study between 1.3-[mu]m optical coherence tomography (OCT) and 40-MHz high-frequency ultrasound (HFUS) is presented to enhance imaging of bladder cancers ex vivo. A standard rat bladder cancer model in which transitional cell carcinoma (TCC) was induced by intravesical instillation of ... [J. Biomed. Opt. 13, 054007 (2008)] published Fri Sep 12, 2008.
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    5. Visualization of the Basement Membrane Zone of the Bladder by Optical Coherence Tomography: Feasibility of Noninvasive Evaluation of Tumor Invasion

      Visualization of the Basement Membrane Zone of the Bladder by Optical Coherence Tomography: Feasibility of Noninvasive Evaluation of Tumor Invasion
      Visualization of the Basement Membrane Zone of the Bladder by Optical Coherence Tomography: Feasibility of Noninvasive Evaluation of Tumor Invasion Barbara Hermesa, Felix Spölerb, Amjad Naamia, Jörg Bornemannc, Michael Förstb, Joachim Grossec, Gerhard Jaksec, Ruth Knüchela Corresponding Author Information email address Received 24 October 2007; accepted 29 February 2008. published online 02 May 2008. Objectives Imaging techniques with high resolution are evolving rapidly for medical applications
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    6. Optical Coherence Tomography as an Adjunct to White Light Cystoscopy for Intravesical Real-Time Imaging and Staging of Bladder Cancer

      Objectives Optical coherence tomography (OCT) is a novel, real-time endoscopic imaging modality that permits delineation of microarchitectural features of bladder lesions. It may provide an extension of conventional cystoscopy by allowing noninvasive examination of bladder tissue at microscopic resolution (10 to 20 μm). The purpose of this study was to examine the application of OCT in augmenting the diagnosis and staging of bladder lesions. Methods We conducted a retrospective institutional review board–approved, single-institution, single-user review on the use of OCT as an adjunct to conventional cystoscopy in 32 patients with a history of bladder cancer (24), primary tumor (6 ...
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    7. Imalux Collaborates with Preventative Oncology International™ in Study of Cervical Cancer in China

      Imalux Collaborates with Preventative Oncology International™ in Study of Cervical Cancer in China

      Dr. Jerome Belinson, a leading researcher ingynecological cancers, and his team from Preventative Oncology International™ (POI),along with Dr. Nancy Tresser, Chief Medical Officer of Imalux Corporation, recentlycollaborated in a controlled 299 patient study of cervical cancer in China.Cervical cancer is the second greatest cause of cancer deaths in women world-wide. It isdirectly linked to the high-risk types of the Human Papillomavirus (HPV). While the currentstandard for cervical cancer diagnosis in the US is based upon the Pap test, the link betweencervical cancer and HPV has made it possible to identify patients at high risk of cervicalcancer by testing ...

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    8. Computer recognition of cancer in the urinary bladder using optical coherence tomography and texture analysis

      Colleen A. Lingley-Papadopoulos, Murray H. Loew, Michael J. Manyak et al. The vast majority of bladder cancers originate within 600 [mu]m of the tissue surface, making optical coherence tomography (OCT) a potentially powerful tool for recognizing cancers that are not easily visible with current techniques. OCT is a new technology, however, and surgeons are not familiar w ... [J. Biomed. Opt. 13, 024003 (2008)] published Mon Apr 14, 2008.
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    9. Optical Coherence Tomography of Cavernous Nerves: A Step Toward Real-Time Intraoperative Imaging During Nerve-Sparing Radical Prostatectomy.

      OBJECTIVES: To demonstrate the use of optical coherence tomography (OCT) for imaging of the cavernous nerve (CN) and periprostatic tissues. The rates of nerve preservation and postoperative potency after radical prostatectomy might improve with better identification of the CN using emerging intraoperative imaging modalities. OCT is an imaging modality that allows for real-time, high-resolution, cross-sectional imaging of tissues. METHODS: Seven male Sprague-Dawley rats underwent surgery using a midline celiotomy to expose the bladder, prostate, and seminal vesicles. The CNs and major pelvic ganglion were identified. Visual identification of the CN was further confirmed by electrical stimulation with simultaneous intracorporeal pressure ...
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    10. The emergence of imaging technology in advanced prostate cancer.

      Related Articles The emergence of imaging technology in advanced prostate cancer. Can J Urol. 2007 Dec;14 Suppl 1:32-8 Authors: Manyak MJ Rapid advances in imaging technology have whetted our collective appetites for practical clinical applications to assist the physician and patient in therapeutic decisions. Current limitations of imaging technology are being addressed by the convergence of technology in materials science, the computer industry, and biology which have led to improvements of diagnostic imaging. Refinements in image acquisition, fusion of images, and outcomes data now suggest use for image-guided therapy. Novel imaging agents and technologies appear to provide improved ...
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    11. Identification and Imaging of the Nerves Responsible for Erectile Function in Rat Prostate, In Vivo, Using Optical Nerve Stimulation and Optical Coherence Tomography

      The cavernous nerves on the prostate surface are responsible for erectile function. Optical diagnostic tools such as optical coherence tomography and laser nerve stimulation may assist in the identification, imaging, and preservation of these microscopic nerves during prostate cancer surgery, and thus, help preserve sexual function after surgery. The feasibility of noncontact laser stimulation of the cavernous nerves is demonstrated in an in vivo rat prostate model with comparison to conventional electrical nerve stimulation. High-resolution optical coherence tomographic images of the nerves are also obtained and compared with histology. These optical technologies may be suitable as surgical guidance tools during ...
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    12. Subcellular imaging of epithelium with time-lapse optical coherence tomography

      We present the first experimental result of direct delineation of the nuclei of living rat bladder epithelium with ultrahigh-resolution optical coherence tomography (uOCT). We demonstrate that the cellular details embedded in the speckle noise in a uOCT image can be uncovered by time-lapse frame ave ... [J. Biomed. Opt. 12, 050504 (2007)] published Wed Oct 24, 2007.
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    13. OCT for Early Detection and Staging of Endobronchial Lung and Pleural Cancer, Airway Injury, and Prostate Cancer

      Optical coherence tomography (OCT) is a non-invasive diagnostic technique that can provide information about tissue abnormalities. This technique uses a near-infrared diode to emit light that can produce images of the specimen under investigation without causing damage or alterations. The research' want to compare the OCT results with that obtained from conventional histologic examination and to show that the OCT results may be almost as accurate as the standard Pathology results. Optical coherence tomography (OCT) is a new technique being developed that can be used for visualizing human tissue. OCT offers a means of providing information on the characteristics and ...
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    169-181 of 181 « 1 2 3 4 5 6 7 8
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