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OCT Products in the News
(1 articles) Michelson Diagnostics Vivosight
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Organizations in the News
(4 articles) University of Connecticut
(4 articles) University of Arizona
(2 articles) University of Central Florida
(2 articles) University of Texas Medical Branch
(1 articles) Ludwig Maximilians Universität München
(1 articles) World Health Organization
(1 articles) Yonsei University
(1 articles) Russian Academy of Sciences
(1 articles) Academic Medical Center at the University of Amsterdam
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Jennifer Barton is one women who wears many hats at University of Arizona
Explore Article azbiz.com (Jul 30 2010)
The University of Arizona’s Jennifer Barton is the assistant director and No. 3 person at Bio5 Institute, she is the department head of the newly established Department of Biomedical Engineering, chair of the Biomedical Engineering Graduate Interdisciplinary Program, and she is a researcher and teaches classes within optics, electrical and computer engineering and biomedical engineering. “Most faculty members end up teaching, doing research and some sort of service,” said Barton, who is also a Arizona Cancer Center member. “My service just happens to be more administrative. It seems like a lot but althugh I wear a lot of different hats, ...
Comment on Article Mentions: Jennifer K. Barton University of Texas at Austin University of Arizona
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Michelson Diagnostics Announces Soft Tissue Probe for In Vivo Imaging of Oral and Gynaecological Tissue
Explore Article Optical Coherence Tomography News (May 24 2010)
(Orpington, UK) May 24, 2010 – Michelson Diagnostics (MDL) the leading provider of clinical OCT imaging systems announces that it has now developed a probe suitable for imaging soft tissue for use with its VivoSight Multi-Beam optical coherence tomography (OCT) imaging system. The probe will allow in vivo imaging of oral and gynaecological tissue. The VivoSight Multi-Beam OCT system provides sub-surface cross-sectional images at far higher resolution than is possible with ultrasound, CT or MRI, and much deeper and wider than is possible with confocal microscopy. The new Soft Tissue Probe provides the same unprecedented imaging quality as the Topical ...
Comment on Article Mentions: Michelson Diagnostics Michelson Diagnostics Vivosight Jon Holmes
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Study of the Diagnostic Efficacy of Real-Time Optical Coherence Tomography as an Adjunct to Unaided Visual Inspection With Acetic Acid for the Diagnosis of Preinvasive and Invasive Neoplasia of the Uterine Cervix
Explore Article LWW Online (Apr 5 2010)
Objectives: To determine the sensitivity and specificity of optical coherence tomography (OCT) as an adjunct to unaided visual inspection using acetic acid (VIA) in the detection of cervical intraepithelial neoplasia 2 (CIN 2) in a real-time clinical evaluation. Background: This clinical study was a prospective cross-sectional comparative trial that screened 1000 patients (aged 30-50 years) in a low-resource setting. Women with abnormal cervical cytology or positive human papillomavirus (HPV) tests were referred for further evaluation including VIA, OCT imaging, colposcopy, and cervical biopsies. Methods: The VIA diagnoses were coded by quadrant. The OCT was then performed in all VIA-positive areas ...
Comment on Article Mentions: Imalux Nancy J. Tresser
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Diagnostic Efficacy of Real-Time Optical Coherence Tomography in the Management of Preinvasive and Invasive Neoplasia of the Uterine Cervix
Explore Article LWW Online (Feb 6 2010)
Objective: Determine the sensitivity and specificity of optical coherence tomography (OCT) as an adjunct to colposcopy in the detection of cervical intraepithelial neoplasia (CIN) grade 2 or higher in a real-time clinical evaluation. Background: Optical coherence tomography (OCT) uses infrared light similar to ultrasound pulse-echo imaging. Image resolution is optimal in the 1-to-3-mm range. This study is the third in our series of OCT investigations and our first real-time clinical trial. The study was conducted at the Peking University Shenzhen Hospital, Shenzhen, China. Methods: Nonpregnant women 18 years or older with abnormal cervical cytologic findings or a positive high-risk human ...
Comment on Article Mentions: Imalux Nancy J. Tresser
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Cervical Soft Tissue Motion Measurement by Optical Coherence Tomography
Explore Article SpringerLink Home (Jan 1 2010)
To design a semi-automatic laser scalpel for tissue resection in the area of neck masses it was necessary to examine the biomechanic behavour of these tissues. The aim was to identify if and to what extent (amplitude and velocity) the tissues shift due to respiration and circulation. This is important since these movements have to be followed by the laser scalpel. At defined points on the neck surface onedimensional (1-D) time related Optical Coherence Tomography OCT measurements were recorded. Tissue shifting in the direction of the OCT-sightaxis was quantified. The preliminary results of these basic experiments shown here will be ... -
Laparoscopic optical coherence tomography imaging of human ovarian cancer
Explore Article Optical Coherence Tomography News (Jun 20 2009)
Feature Of The Week 6/21/09: Ovarian cancer is the fourth leading cause of cancer-related death among women in the US, largely attributed to late detection due to unreliable symptomology and screening tools without adequate resolution and specificity. As a result, ovarian cancer is often diagnosed a
Comment on Article Mentions: Jennifer K. Barton University of Arizona Molly Brewer
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Laparoscopic optical coherence tomography imaging of human ovarian cancer
Explore Article ScienceDirect (Jun 2 2009)
Objectives Ovarian cancer is the fourth leading cause of cancer-related death among women in the US largely due to late detection secondary to unreliable symptomology and screening tools without adequate resolution. Optical coherence tomography (OCT) is a recently emerging imaging modality with promise in ovarian cancer diagnostics, providing non-destructive subsurface imaging at imaging depths up to 2 mm with near-histological grade resolution (10–20 μm). In this study, we developed the first ever laparoscopic OCT (LOCT) device, evaluated the safety and feasibility of LOCT, and characterized the microstructural features of human ovaries in vivo. Methods A custom LOCT device was fabricated ...Comment on Article Mentions: Jennifer K. Barton University of Arizona University of Connecticut
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In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging
Explore Article opticsinfobase.org (May 12 2009)
In vitro three-dimensionalmodels for metastatic ovarian cancer have been useful for recapitulating the human disease. These spheroidal tumor cultures, however, can grow in excess of 1 mm in diameter, which are difficult to visualize without suitable imaging technology.Optical coherence tomography (OCT) is an ideal live imaging method for non-perturbatively visualizing these complex systems. OCT enabled detailed observations of the model at both nodular and cellular levels, revealing growth dynamics not previously observed. The development of a time-lapse OCT system, capable of automated, multidimensional acquisition, further provided insights into the growth and chemotherapeutic response of ovarian cancer.
Comment on Article Mentions: Johannes F. de Boer Massachusetts General Hospital Harvard University
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Optical coherence tomography as a non-invasive imaging technique for examination of cervical tissue
Explore Article ScienceDirect (May 8 2009)
Objective Optical coherence tomography (OCT) is a non-invasive high-resolution real-time imaging technique that permits delineation of features up to 2 mm in depth. The purpose of this study was to examine the capabilities of OCT in characterizing cancerous and precancerous lesions of the uterine cervix. Patients and methods We conducted a single-institution, review board-approved, prospective study on the use of OCT as an adjunct to standard colposcopy and biopsy in 25 women with suspected cervical intraepithelial neoplasia (CIN). OCT images of suspicious areas were obtained before biopsy, interpreted in real time and subsequently compared with the corresponding histology. Results We ...Comment on Article Mentions: Ludwig Maximilians Universität München
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High Resolution Imaging of Epithelial Injury in the Sheep Cervicovaginal Tract: A Promising Model for Testing Safety of Candidate Microbicides
Explore Article Sexually Transmitted Diseases (Apr 26 2009)
Abstract: Background: Access to readily available large animal models and sensitive noninvasive techniques that can be used for the evaluation of microbicide-induced changes in tissue could significantly facilitate preclinical evaluations of microbicide safety. The sheep cervicovaginal tract, with stratified squamous epithelium similar to humans, holds promise as a large animal model used before nonhuman primates. In addition, optical coherence tomography (OCT) could enable high resolution visualization of tissue morphology and noninvasive assessment of microbicide-induced epithelial injury. Methods: We evaluated the dose response of sheep cervicovaginal tract to benzalkonium chloride (BZK). Twenty sheep received treatment with phosphate-buffered saline or BZK solution ...Comment on Article Mentions: Massoud Motamedi University of Texas Medical Branch World Health Organization
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A prototype hybrid intraoperative probe for ovarian cancer detection
Explore Article opticsinfobase.org (Apr 19 2009)
A novel prototype intraoperative system combining positron detection and optical coherence tomography (OCT) imaging has been developed for early ovarian cancer detection. The probe employs eight plastic scintillating fiber tips for preferential detection of local positron activity surrounding a central scanning OCT fiber providing volumetric imaging of tissue structure in regions of high radiotracer uptake. Characterization measurements of positron sensitivity, spatial response, and position mapping are presented for Tl204/Cs137 sources as well as 18F-FDG. In conjunction with co-registered frequency domain OCT measurements the results demonstrate the potential for a miniaturized laparoscopic probe offering simultaneous functional localization and structural imaging for ...
Comment on Article Mentions: Molly Brewer Shikui Yan Yueli Chen
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Imalux® Corporation and Preventive Oncology International®, Inc. Differentiate Grades of Pre-Invasive Cervical Dysplasia with Niris Optical Coherence Tomography Imaging System
Explore Article businesswire.com (Feb 24 2009)
Imalux Corporation and Preventive Oncology International, Inc. (POI) conducted two studies to determine the diagnostic efficacy of “real time” Optical Coherence Tomography (OCT). The first study was held in December 2007 and the second in April 2008. Both IRB-approved studies took place in China in partnership with the Peking University Shenzhen Hospital and the Renmin Hospital in Buyi-Miao Autonomous District of Guizhou Province. Two thousand (2000) women participated in the studies and approximately two thousand eight hundred (2,800) OCT images were taken and were compared to diagnostic impression and pathologic findings to determine the accuracy of OCT. The studies yielded ...Comment on Article Mentions: Imalux Imalux Niris Nancy J. Tresser
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Digital colposcopy: ready for use? An overview of literature
Explore Article www3.interscience.wiley.com (Dec 17 2008)
The aims of this review were to summarise the various methods of digital colposcopy and to provide an overview of their efficacy. We conducted a literature search and focused on papers that described a technique for colposcopy, other than conventional colposcopy, and compared this with conventional colposcopy and/or histology and included digitalisation of the process. All papers have been classified in one of the following categories: digital imaging and telecolposcopy, spectroscopy, computerised colposcopy, optical coherence tomography and confocal microcolposcopy. Among the most promising developments is spectroscopy, allowing a more or less automated analysis and interpretation of the colposcopic image.Comment on Article Mentions: Academic Medical Center at the University of Amsterdam
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Review: Optical Micrometer Resolution Scanning for Non-invasive Grading of Precancer in the Human Uterine Cervix
Explore Article TCRT Online (Dec 3 2008)
Management of cervical precancer is archetypal for other cancer prevention programmes but has to consider diagnostic and logistic challenges. Numerous optical tools are emerging for non-destructive near real-time early diagnosis of precancerous lesions of the cervix. Non-destructive, real-time imaging modalities have reached pre-commercial status, but high resolution mapping tools are not yet introduced in clinical settings. The NCBI PubMed web page was searched using the keywords ‘CIN diagnosis’ and the combinations of ‘cervix {confocal, optical coherence tomography, ftir, infrared, Raman, vibrational, spectroscopy}’. Suitable titles were identified and their relevant references followed. Challenges in precancer management are discussed. The following tools ...Comment on Article Mentions: Florian Bazant-Hegemark
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Imalux Collaborates with Preventative Oncology International™ in Study of Cervical Cancer in China
Explore Article Welcome to Imalux (Jun 24 2008)
Comment on Article Mentions: Imalux Nancy J. Tresser Russian Academy of Sciences
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