1. Articles in category: Cardiology

    481-504 of 2468 « 1 2 ... 18 19 20 21 22 23 24 ... 101 102 103 »
    1. Volcano Corporation (VOLC): Investor Activism Erupts At Volcano

      Volcano Corporation (VOLC): Investor Activism Erupts At Volcano

      While shareholder activism is a fact of life in the pharma sphere, it is less common in medtech. But this could be changing. The worrying downturn in medtech M&A over the past year means that some investors are getting restless as an exit is denied them, and more and more may take it upon themselves to ensure companies make appealing takeover targets. Volcano Corp. ( VOLC ), a cardiovascular imaging device developer, might be the bellwether. The investment fund Engaged Capital, which has a 5.1% stake in Volcano, is trying to steer the company towards a $200m share buyback and ...

      Read Full Article
    2. Rising Incidence of Peripheral and Coronary Artery Diseases to Drive Demand for IVUS Imaging, According to New Report by Global Industry Analysts, Inc.

      Rising Incidence of Peripheral and Coronary Artery Diseases to Drive Demand for IVUS Imaging, According to New Report by Global Industry Analysts, Inc.

      GIA announces the release of a comprehensive global report on Intravascular Ultrasound (IVUS) markets. Global market for Intravascular Ultrasound (IVUS) is forecast to reach US$695.7 million by 2018, driven by rising incidence of peripheral and coronary artery diseases aggravated by poor lifestyle habits and increasing prevalence of co-morbid conditions including diabetes and obesity.

      Read Full Article
    3. Volcano Corporation Cancels its Intravascular OCT Development Program?

      Volcano Corporation Cancels its Intravascular OCT Development Program?

      Volcano corporation recently reported on its third quarter results and announced a strategic reprioritization initiative which among other things stated that it was discontinuation development of its Optical Coherence Tomography intravascular imaging product. The report can be seen HERE . It is unclear why Volcano took this position on OCT specially since it saved a small amount of near term R&D dollars and there is a big potential market that threatens the IVUS market (a Volcano strength). But lots of potential factors could be at play including a recent big drop it is stock value (see Link ) due to investor ...

      Read Full Article
    4. Volcano Reports Third Quarter Results

      Volcano Reports Third Quarter Results

      Volcano Corporation (Nasdaq: VOLC), a leading developer and manufacturer of precision guided therapy tools designed to enhance the diagnosis and treatment of coronary and peripheral vascular disease, today reported results for the third quarter and first nine months of 2013. The company also today announced a strategic reprioritization and reallocation of resources within its distribution, research and development and clinical programs to focus on areas of strong projected growth in FFR (Fractional Flow Reserve), peripheral applications, coronary IVUS (Intravascular Imaging) driven by the ADAPT-DES clinical data and Axsun Medical. This has resulted in a corporate restructuring charge that reflects the ...

      Read Full Article
    5. Cardiovascular Device Markets Reach Billions

      Cardiovascular Device Markets Reach Billions

      iData Research , the leading global authority in medical device and pharmaceutical market research, has published a new report series for the U.S. Cardiology Device Markets. Cardiovascular disease is much more prevalent among patients over 55 years of age; therefore as the U.S. population ages, the incidence of cardiovascular disease will increase. In addition, rising rates of obesity will also contribute to the incidence of heart disease. As the baby boomer generation in the U.S. ages, the patient population will increase. This increase in the patient population will lead to an annual 3% to 4% increase in the ...

      Read Full Article
    6. Feature Of The Week 11/3/13: 3D Assessment of Stent Cell Size and Side Branch Access in Intravascular OCT

      Feature Of The Week 11/3/13: 3D Assessment of Stent Cell Size and Side Branch Access in Intravascular OCT

      We present a semi-automatic approach to assess the maximum circular unsupported surface area (MCUSA) of selected stent cells and the side branch access through stent cells in intravascular optical coherence tomography (IVOCT) pullback runs. Such 3D information may influence coronary interventions, stent design, blood flow analysis or prognostic evaluation. First, the stent struts are detected automatically and stent cells are reconstructed with users’ assistance. Using cylinder fitting, a 2D approximation of the stent cell is generated for MCUSA detection and measurement. Next, a stent surface is reconstructed and stent-covered side branches are detected. Both the stent cell contours and side ...

      Read Full Article
    7. Pulmonary Hypertension in Mitral Stenosis: An Optical Coherence Tomography Study

      Pulmonary Hypertension in Mitral Stenosis: An Optical Coherence Tomography Study

      A 65-year old woman with a prior history of surgical mitral comissurotomy 30 years ago presented with a 6-month history of worsening fatigue and exertional dyspnea. On physical examination, she had a mitral stenosis murmur, a loud P2, with an irregular pulse and mild peripheral edema. The electrocardiogram showed atrial fibrillation; the echocardiogram was notable for a fibro-calcified mitral valve, with severe restriction of leaflet mobility and an area of 1.1 cm2 . Biventricular function was normal. As the valve anatomy was considered suitable for percutaneous intervention, the patient was scheduled a balloon valvuloplasty. The pre-intervention right heart catheterization showed ...

      Read Full Article
    8. Optical coherence tomography evaluation of late strut coverage patterns between first-generation drug-eluting stents and everolimus-eluting stent

      Optical coherence tomography evaluation of late strut coverage patterns between first-generation drug-eluting stents and everolimus-eluting stent

      Objectives To compare strut coverage patterns between everolimus-eluting stent (EES) and first-generation drug-eluting stents (DES) at more than 12 months after successful implantation, using optical coherence tomography (OCT). Background No sufficient OCT data has been reported comparing late strut coverage patterns between EES and first-generation DES. The favorable late results after EES implantation could be related to lower rates of uncovered and malapposed struts. Methods A total of 66 DES (21 EES, 23 SES, and 22 PES) that were implanted at least 1 year in advance in 40 patients and met good late angiographic results were evaluated by OCT. The ...

      Read Full Article
    9. Hendrick Medical Center Offers New Cardiac Machine

      Hendrick Medical Center Offers New Cardiac Machine

      Hendrick Medical Center is enhancing their Cardiac department by offering new cutting edge technology. Hendrick is one of of only five medical facilities in the country to offer the resources from a machine called The Optical Coherence Tomography, or OCT. This high-tech machine is equipped with 3D screening allowing a 360-degree view inside the artery. Cardiologist Harvi Arora says this new technology will allow him to see important details that can easily be missed or not visible with older technology.

      Read Full Article
    10. Neoatherosclerosis and Mural Thrombus Detection After Sirolimus-Eluting Stent Implantation

      Neoatherosclerosis and Mural Thrombus Detection After Sirolimus-Eluting Stent Implantation

      Background:  Although both optical coherence tomography (OCT) and angioscopy are robust tools for detecting intrastent thrombi and neoatherosclerosis in vivo, whether OCT findings are comparable with angioscopy findings remains unclear. Methods and Results:  22 patients presenting with de novo lesions underwent 26 sirolimus-eluting stent (SES) implantations, with follow-up OCT and angioscopy at 10 months post-implantation for segmental assessment of the proximal, mid-, and distal SES segments (66 segments). The mean signal intensity index (signal intensity of the neointima/signal intensity of fibrous intimal hyperplasia) was quantified for angioscopically detected in-stent yellow and white segments. The detection rate for red thrombi ...

      Read Full Article
    11. Volcano Announces New Two-Year Results of Largest Prospective Study of Use of IVUS in Stent Placement

      Volcano Announces New Two-Year Results of Largest Prospective Study of Use of IVUS in Stent Placement

      Volcano Corporation (NASDAQ: VOLC), a leading developer and manufacturer of precision guided tools designed to enhance the diagnosis and treatment of coronary and peripheral vascular disease, today announced new two-year outcomes from an analysis of use of intravascular ultrasound (IVUS) in the ADAPT-DES ( A ssessment of D ual A nti P latelet T herapy with D rug- E luting S tents) Study, the largest prospective registry of IVUS use to date. Results suggest that, in the ADAPT-DES study, use of IVUS with angiography (compared with angiography alone) in placing the current generation of drug-eluting stents (DES) was associated with reductions ...

      Read Full Article
    12. Volcano Corporation Announces Third Quarter 2013 Revenues, Updated Revenue Guidance For Full Year 2013 And Preliminary Revenue Guidance For 2014

      Volcano Corporation Announces Third Quarter 2013 Revenues, Updated Revenue Guidance For Full Year 2013 And Preliminary Revenue Guidance For 2014

      Volcano Corporation (Nasdaq: VOLC), a leading developer and manufacturer of precision guided therapy tools designed to enhance the diagnosis and treatment of coronary and peripheral vascular disease, said today that it expects revenues for the third quarter of 2013 on a reported basis will be approximately $95.8 million. This compares with revenues on a reported basis of $93.7 million in the same period a year ago. The company said that FX exchange rates had a negative impact of approximately $5.4 million compared to the third quarter a year ago. Medical segment revenues increased approximately three percent and ...

      Read Full Article
    13. Coronary artery aneurysm following stent implantation: insights from serial multiple intravascular imaging modalities

      Coronary artery aneurysm following stent implantation: insights from serial multiple intravascular imaging modalities

      Coronary artery aneurysms after coronary intervention are rare and most ‘aneurysms’ are, in fact, pseudoaneurysms rather than true aneurysms. A correct diagnosis is mandatory for optimal management of this rare coronary complication. Intravascular ultrasound (IVUS) has become the gold standard for providing crucial information on the anatomical composition of the vessel wall, necessary to achieve the diagnosis. On the other hand, optical coherence tomography (OCT) is the most accurate diagnostic tool for providing luminal coronary measurement,

      Read Full Article
    14. Neoatherosclerosis 16 years following bare-metal stent implantation: Different tissue components in different underlying lesions observed with optical coherence tomography

      Neoatherosclerosis 16 years following bare-metal stent implantation: Different tissue components in different underlying lesions observed with optical coherence tomography

      A 61 years old male with a history of multiple treatments of percutaneous coronary intervention (PCI) with bare-metal stents (BMS) was admitted for the treatment of acute coronary syndrome (ACS). Sixteen years prior to this admission when he was 45years old, he experienced inferior ST-elevation myocardial infarction. He received one Palmaz-Schatz Stent (PS) for the treatment of lesion in distal right coronary artery (RCA).

      Read Full Article
    15. Better Inflation time of stent balloon on stent expansion and apposition: an optical coherence tomography study

      Better Inflation time of stent balloon on stent expansion and apposition: an optical coherence tomography study

      Purpose: Adequate stent expansion and apposition are important for maintaining good clinical outcomes after coronary intervention. We determined the effect of inflation time of the stent balloon on stent expansion and apposition using optical coherence tomography. Methods: Subjects included 17 patients (18 de novo coronary artery lesions), in whom Resolute Integrity® (n=9) and Xience prime® (n=9) were deployed. The stents were inflated three times in all cases at the nominal inflation pressures (8.9±0.6 atm) by the stent delivery balloon with different inflation times of first, 15 seconds and 30 seconds. The first inflation time was ...

      Read Full Article
    16. Association between prior aspirin use and optical coherence tomography findings in type II diabetes mellitus patients presenting with first acute coronary events

      Association between prior aspirin use and optical coherence tomography findings in type II diabetes mellitus patients presenting with first acute coronary events

      Aims: Aspirin has been shown to be beneficial in the primary prevention, secondary prevention, and treatment of acute coronary syndromes (ACS). However, it is less clear whether prior aspirin therapy affects lesion morphology in ACS. The aim of the present study is to investigate the association between prior aspirin use and the culprit lesion morphology examined by optical coherence tomography (OCT) in patients with the first ACS event. We further performed subgroup analysis on the basis of the presence or the absence of type 2 diabetes mellitus (DM). Methods and results: We studied 250 patients with the first ACS event ...

      Read Full Article
      Mentions: Yoshito Iesaka
    17. Serial assessment of vessel interactions after drug-eluting stent implantation in unprotected distal left main coronary artery disease using frequency-domain optical coherence tomography

      Serial assessment of vessel interactions after drug-eluting stent implantation in unprotected distal left main coronary artery disease using frequency-domain optical coherence tomography

      Objectives This study sought to assess stent-vessel interactions after drug-eluting stent (DES) implantation in unprotected left main coronary artery (ULM) by frequency-domain optical coherence tomography (FD-OCT). Background Percutaneous coronary intervention using DES in ULM has been increasingly performed in routine practice. Recently, FD-OCT assessments of DES-vessel interactions have been used as surrogates for DES safety; however, there are no FD-OCT studies in ULM. Methods We prospectively enrolled 33 consecutive patients with ULM disease treated with sirolimus- (n = 11) and everolimus-eluting stents (n = 22). FD-OCT assessments were performed post-percutaneous coronary intervention and at 9-month follow-up. Three different segments of ULM were ...

      Read Full Article
    18. Ocelot catheter for the recanalization of lower extremity arterial chronic total occlusion: Mini review

      Ocelot catheter for the recanalization of lower extremity arterial chronic total occlusion: Mini review

      Peripheral arterial disease (PAD) is a growing clinical condition affecting more than 10 million patients in the United States and it is responsible for more than 120,000 amputations annually. The presence of chronic total occlusions (CTO) increases the complexity of endovascular procedures and open surgery may often be the preferred approach. Despite the optimization of the CTO devices and technique, percutaneous CTO revascularization remains a challenging procedure even for experienced operators with important complication rates. The Ocelot TM system is a novel CTO device to use real-time optical coherence tomography (OCT) imaging guidance for the recanalization of peripheral CTOs ...

      Read Full Article
    19. Radial artery complications occurring after transradial coronary procedures using long hydrophilic-coated introducer sheath: a frequency domain-optical coherence tomography study

      Radial artery complications occurring after transradial coronary procedures using long hydrophilic-coated introducer sheath: a frequency domain-optical coherence tomography study

      This study was performed to analyze the impact of transradial intervention (TRI), performed by long (25-cm) hydrophilic-coated radial introducer sheath (HRS), on radial artery (RA). Both acute damages and chronic intimal modifications, occurring in RA, were assessed using frequency domain-optical coherence tomography (FD-OCT). FD-OCT evaluation of RA was performed in 51 consecutive patients, undergoing TRI by long (25-cm) HRS. FD-OCT was performed from RA ostium to the puncture site. Acute damages such as intimal tears and medial dissections together with chronic intimal modifications, assessed as intimal hyperplasia indexes, were observed and compared between proximal and distal RA segments. Intimal tears ...

      Read Full Article
    20. Optical coherence tomography derived differences of plaque characteristics in coronary culprit lesions between type 2 diabetic patients with and without acute coronary syndrome

      Optical coherence tomography derived differences of plaque characteristics in coronary culprit lesions between type 2 diabetic patients with and without acute coronary syndrome

      Objective : To compare optical coherence tomography (OCT)-derived plaque characteristics of coronary target lesions between diabetic patients with acute coronary syndrome (ACS) versus stable angina pectoris (SAP). Background : In vivo assessment of plaque composition of coronary culprit lesions in a cardiovascular high-risk population with diabetes mellitus is incompletely elucidated. Methods : 102 diabetic patients with coronary de novo lesions were enrolled and categorized into an ACS-group (40 patients) and a SAP-group (62 patients) according to their clinical presentation. Assessment of clinical data, angiographic and OCT imaging including the analysis of plaque composition and lipid content of the target lesions were performed ...

      Read Full Article
    21. Comparison of diagnostic accuracy between multidetector computed tomography and virtual histology intravascular ultrasound for detecting optical coherence tomography-derived fibroatheroma

      Comparison of diagnostic accuracy between multidetector computed tomography and virtual histology intravascular ultrasound for detecting optical coherence tomography-derived fibroatheroma

      Histopathological studies have reported that optical coherence tomography (OCT) can accurately detect fibroatheroma that is involved in not only culprit lesion of acute coronary syndrome but also no-reflow phenomenon after percutaneous coronary intervention. Studies have demonstrated superiority of OCT in plaque characterization and interruption of arterial wall component. At current, multidetector computed tomography (MDCT) and virtual histology intravascular ultrasound (VH-IVUS) are considered as alternative imaging devices for coronary plaque characterization. This study aimed to compare the diagnostic accuracy for detecting fibroatheroma between MDCT and VH-IVUS using OCT as the reference standard. Forty-three lesions from 27 patients assessed by MDCT, VH-IVUS ...

      Read Full Article
    22. Transform OCT TRiple Assessment of Neointima Stent FOrmation to Reabsorbable polyMer With Optical Coherence Tomography

      Transform OCT TRiple Assessment of Neointima Stent FOrmation to Reabsorbable polyMer With Optical Coherence Tomography

      First prospective randomized controlled study to evaluate in an 'all-comers' population with coronary artery disease whether treatment with a novel everolimus eluting stent (EES) with a biodegradable polymer is superior to a durable polymer zotarolimus eluting stent (ZES), with respect to the long term vascular response to treatment These data are important to ascertain the superiority of a new generation DES with bioabsorbable polymer coating to reduce the long term development of in-stent neoatherosclerosis.

      Read Full Article
      Mentions: Giulio Guagliumi
    23. Optical coherence tomography and histopathological assessment of delayed arterial healing after drug-eluting stent implant in a pig coronary model

      Optical coherence tomography and histopathological assessment of delayed arterial healing after drug-eluting stent implant in a pig coronary model

      Background Delayed healing, such as persistent inflammation and fibrin deposition, and vascular dysfunction after drug-eluting stent has been reported. Histological validation of coronary optical coherence tomography (OCT) morphology has not yet been done. Methods Sirolimus eluting stents (SES, n = 8) and bare metal stents (BMS n = 8) were implanted in pig coronary arteries. One month after implantation, an acetylcholine challenge test and OCT were performed. The OCT texture pattern of the neointima was classified into one of the three categories; Layered type, Homo type, and Hetero type. Hearts were harvested for histopathological scoring of inflammation and intramural thrombus. Results Inflammation ...

      Read Full Article
    24. Stent malapposition, as a potential mechanism of very late stent thrombosis after bare-metal stent implantation: A case report

      Stent malapposition, as a potential mechanism of very late stent thrombosis after bare-metal stent implantation: A case report

      A 90-year-old man was admitted to our hospital with acute ST-segment elevation myocardial infarction. He had a history of post-infarction angina pectoris 79 months ago and had a bare-metal stent (BMS) implanted in the proximal left anterior descending artery at our hospital. Emergent coronary angiography demonstrated thrombotic occlusion in the previously stented segment. After catheter thrombectomy, antegrade flow was restored, but 90% stenosis with haziness persisted in the proximal and distal portions of the previously stented segment. Intravascular ultrasound imaging showed interstrut cavities or stent malapposition at the proximal and distal sites of stented segment. In close proximity to the ...

      Read Full Article
    481-504 of 2468 « 1 2 ... 18 19 20 21 22 23 24 ... 101 102 103 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (3 articles) Yonsei University
    2. (1 articles) Harvard University
    3. (1 articles) Korea University
    4. (1 articles) University of Texas at Austin
    5. (1 articles) University of Athens
    6. (1 articles) Wakayama Medical University
    7. (1 articles) Cardiovascular Research Foundation
    8. (1 articles) University of Tsukuba
    9. (1 articles) Harbin Medical University
    10. (1 articles) Imperial College London
    11. (1 articles) University of Texas Health Science Center
    12. (1 articles) Hanyang University
  4. People in the News

    1. (3 articles) Yangsoo Jang
    2. (3 articles) Myeong-Ki Hong
    3. (3 articles) Jung-Sun Kim
    4. (3 articles) Dong Hoon Choi
    5. (2 articles) Renu Virmani
    6. (2 articles) Young-Guk Ko
    7. (2 articles) Michael Joner
    8. (1 articles) Tsunenari Soeda
    9. (1 articles) Hang Lee
    10. (1 articles) Bo Yu
    11. (1 articles) Ik-Kyung Jang
    12. (1 articles) Shiro Uemura