1. Articles in category: Cardiology

    3841-3864 of 4007 « 1 2 ... 158 159 160 161 162 163 164 ... 165 166 167 »
    1. Peering into the Heart, Safely

      Peering into the Heart, Safely
      Getting a high-resolution picture of the interior of a coronary artery is difficult: to take a scan using existing technology, the heart has to be kept free of blood for 30 seconds. A new approach could dramatically reduce the time required for imaging, making it safer and easier for doctors to check stents for stability and keep track of new scar tissue. The new method builds on an old technique called optical coherence tomography (OCT). This high-resolution medical imaging system has been in use in ophthalmology for more than a decade and is occasionally used to scan coronary arteries. But ...
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    2. Evaluation of collagen in atherosclerotic plaques: the use of two coherent laser-based imaging methods

      Abstract  Acute coronary events such as myocardial infarction are frequently caused by the rupture of unstable atherosclerotic plaque. Collagen plays a key role in determining plaque stability. Methods to measure plaque collagen content are invaluable in detecting unstable atherosclerotic plaques. Recently, novel coherent laser-based imaging techniques, such as polarization-sensitive optical coherence tomography (PSOCT) and laser speckle imaging (LSI) have been investigated, and they provide a wealth of information related to collagen content and plaque stability. Additionally, given their potential for intravascular use, these technologies will be invaluable for improving our understanding of the natural history of plaque development and rupture ...
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    3. Coronary bioabsorbable magnesium stent: 15-month intravascular ultrasound and optical coherence tomography findings

      Peter Barlis, Jun Tanigawa and Carlo Di Mario A 65-year-old man underwent elective percutaneous coronary intervention for a stenosis in the proximal left anterior descending artery (LAD). As part of the PROGRESS study (designed as a first-in-man coronary study in 65 patients in seven European centres), a 3.5 x
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    4. Optical Coherence Tomography Imaging as a Quality Assurance Tool for Evaluating Endoscopic Harvest of the Radial Artery

      Background: Concerns about intimal disruption and spasm have limited enthusiasm for endoscopic radial artery harvest (ERAH), although the risk of these problems after this procedure remains uncertain. Radial artery conduits were screened intraoperatively before and after ERAH vs open harvest using catheter-based high-resolution optical coherence tomography (OCT) imaging. Methods: Twenty-four cadavers and 60 coronary artery bypass graft (CABG) patients scheduled to receive a RA graft underwent OCT imaging before (in situ) and after (ex vivo) open harvest or ERAH. Spasm was quantified by the percentage change in luminal volume between images. Intimal disruption was classified as minor or severe depending ...
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    5. Neointimal coverage of sirolimus-eluting stents 6 months and 12 months after implantation: evaluation by optical coherence tomography

      Background  Optical coherence tomography (OCT) is a new imaging modality with resolution of approximately 10 μm and can be employed to visualize intracoronary characteristics. Sirolimus-eluting stents (SES) are susceptible to late thrombosis due to delayed re-endothelialization over the stent struts, which may result in acute myocardial infarction or death. This study was designed to evaluate the re-endothelialization and neointimal coverage of SES with OCT 6 months and 12 months after implantat
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    6. Neointimal coverage of sirolimus-eluting stents 6 months and 12 months after implantation: evaluation by optical coherence tomography.

      BACKGROUND: Optical coherence tomography (OCT) is a new imaging modality with resolution of approximately 10 microm and can be employed to visualize intracoronary characteristics. Sirolimus-eluting stents (SES) are susceptible to late thrombosis due to delayed re-endothelialization over the stent struts, which may result in acute myocardial infarction or death. This study was designed to evaluate the re-endothelialization and neointimal coverage of SES with OCT 6 months and 12 months after implantation. METHODS: A total of 36 patients enrolled in the study underwent OCT examination 6 months (17 patients) and 12 months (19 patients) after SES implantation. The strut apposition to ...
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    7. Volcano Announces U.S. and European Launch of Rotational IVUS and Integrated FFR

      Volcano s5i platform offers multiple diagnostic modalities on a single system and user interface, providing choice for the first time to physicians and administrators SAN DIEGO, March 28 /PRNewswire-FirstCall/ -- Volcano Corporation (Nasdaq: VOLC), a leading manufacturer and developer of intravascular ultrasound (IVUS), functional measurement (FM) and Optical Coherence Tomography (OCT) products designed to enhance the diagnosis and treatment of coronary and peripheral vascular disease, announced
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    8. Volcano Announces US And European Launch Of Rotational IVUS And ...

      Volcano Announces U.S. And European Launch Of Rotational IVUS And Integrated FFR Volcano Corporation (NASDAQ: VOLC), a leading manufacturer and developer of intravascular ultrasound (IVUS), functional measurement (FM) and Optical Coherence Tomography (OCT) products designed to enhance the diagnosis and treatment of coronary and peripheral vascular disease, announced the U.S. This entry was posted on Friday, March 28th, 2008 at 14:00 and is filed under All. You can follow any responses to this en
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    9. Combined MRI/OCT for Image Guidance of CTOs

      Chronic Total Occlusions (CTOs) are generally defined as occlusions within an artery of 1 month or older. Chronic total occlusions begin as thrombus but gradually become heavily cross-linked collagen as they age. Traditionally the lack of an effective guidance means, as well as the high restenosis rate of CTOs, has made minimally invasive catheter-based intervention difficult. As a result, these cases are mostly sent to bypass surgery. With the advent of drug-eluting stents, new devices have beg
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    10. Electrostatic forward-viewing scanning probe for Doppler optical coherence tomography using a dissipative polymer catheter

      Nigel R. Munce, Adrian Mariampillai, Beau A. Standish, Mihaela Pop, Kevan J. Anderson, George Y. Liu, Tim Luk, Brian K. Courtney, Graham A. Wright, I. Alex Vitkin, Victor X. D. Yang. A novel flexible scanning optical probe is constructed with a finely etched optical fiber strung through a platinum coil in the lumen of a dissipative polymer. The packaged probe is 2.2mm in diameter with a rigid length of 6mm when using a ball lens or 12mm when scanning the fiber proximal to a ... [Opt. Lett. 33, 657-659 (2008)]
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    11. A bioabsorbable everolimus-eluting coronary stent system for patients with single de-novo coronary artery lesions (absorb): a prospective open-label trial.

      BACKGROUND: A fully bioabsorbable drug-eluting coronary stent that scaffolds the vessel wall when needed and then disappears once the acute recoil and constrictive remodelling processes have subsided has theoretical advantages. The bioasorbable everolimus-eluting stent (BVS) has a backbone of poly-L-lactic acid that provides the support and a coating of poly-D,L-lactic acid that contains and controls the release of the antiproliferative agent everolimus. We assessed the feasibility and safety of this BVS stent. METHODS: In this prospective, open-label study we enrolled 30 patients who had either stable, unstable, or silent ischaemia and a single de-novo lesion that was suitable for ...

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    12. Optical coherence tomography assessment of vulnerable plaque rupture: predilection for the plaque ‘shoulder’

      Atherosclerosis as a disease entity remains an intensely researched field, given the tendency for considerable morbidity and mortality. This attention has given rise to exciting opportunities in developing tools aimed at early detection and possible targeting of specific therapeutic interventions. One such modality is optical coherence tomography (OCT
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    13. High-resolution in vivo imaging of the cross-sectional deformations of contracting embryonic heart loops using optical coherence tomography

      The embryonic heart tube consists of an outer myocardial tube, a middle layer of cardiac jelly, and an inner endocardial tube. It is said that tubular hearts pump the blood by peristaltoid contractions. The traditional concept of cardiac peristalsis sees the cyclic deformations of pulsating heart tubes as concentric narrowing and widening of tubes of circular cross-section. We have visualized the cross-sectional deformations of contracting embryonic hearts in chick embryos (HH-stages 9-17) using real-time high-resolution optical coherence tomography. Cardiac contractions are detected from HH-stage 10 onward. During the cardiac cycle, the myocardial tube undergoes concentric narrowing and widening while the ...
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    14. Semi-automatic matching of OCT and IVUS images for image fusion

      Olivier Pauly, Gozde Unal, Greg Slabaugh et al. Medical imaging is essential in the diagnosis of atherosclerosis. In this paper, we propose the semi-automatic matching of two promising and complementary intravascular imaging techniques, Intravascular Ultrasound (IVUS) and Optical Coherence Tomography (OCT), with the ultimate goal of producing hyb ... [Proc. SPIE Int. Soc. Opt. Eng. 6914, 69142N (2008)] published Tue Mar 11, 2008.
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      Mentions: Siemens
    15. A novel approach for quantitative analysis of intracoronary optical coherence tomography: high inter-observer agreement with computer-assisted contour detection.

      A novel approach for quantitative analysis of intracoronary optical coherence tomography: high inter-observer agreement with computer-assisted contour detection. Catheter Cardiovasc Interv. 2008 Mar 6; Authors: Tanimoto S, Rodriguez-Granillo G, Barlis P, de Winter S, Bruining N, Hamers R, Knappen M, Verheye S, Serruys PW, Regar E Objective: This study aims to examine observer-related variability of quantitative optical coherence tomography (OCT) derived measurements from both in vitro and in vivo pullback data. Background: Intravascular OCT is a new imaging modality using infrared light and offering 10 times higher image resolution (15 mum) compared to intravascular ultrasound. The quantitative analysis of in ...
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    16. Permeability of hyperosmotic agent in normal and atherosclerotic vascular tissues

      Noninvasive cardiovascular imaging could lead to the early detection and timely treatment of complex atherosclerotic lesions responsible for major cardiovascular events. Recent investigations have suggested that optical coherence tomography (OCT) is an ideal diagnostic tool due to the high resolution this technology achieves in discriminating the different features of atherosclerotic lesions based on structural imaging. We explore the capability of OCT for functional imaging of normal and atherosclerotic aortic tissues based on time- and depth-resolved quantification of the permeability of biomolecules through these tissues. The permeability coefficient of 20% aqueous solution of glucose was found to be (6.80±0 ...
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    17. Amplified Dispersive Optical Tomography. (arXiv:0802.0885v2 ...

      Optical coherence tomography (OCT) has proven to be a powerful technique for studying tissue morphology in ophthalmology, cardiology, and endomicroscopy. Its performance is limited by the fundamental trade-off between the imaging sensitivity and acquisition speed -- a predicament common in virtually all imaging systems. In this paper, we circumvent this limit by using distributed Raman post-amplification of the reflection from the sample. We combine the amplification with simultaneously performe
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    18. Imaging the vitreous: optical coherence tomography and ultrasound imaging.

      Related Articles Imaging the vitreous: optical coherence tomography and ultrasound imaging. Eye. 2008 Feb 22; Authors: Restori M Imaging the vitreous in optically transparent and translucent ocular media using OCT and in optically opaque ocular media using ultrasound is discussed.Optical coherence tomography and colour flow mapping are briefly described. Images of tomograms, B-mode sections, and colour flow maps illustrate the use of these techniques in imaging the vitreous.Eye advance online publication, 22 February 2008; doi:10.1038/eye.2008.30. PMID: 18292783 [PubMed - as supplied by publisher]
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    19. Imaging the vitreous: optical coherence tomography and ultrasound imaging

      Imaging the vitreous in optically transparent and translucent ocular media using OCT and in optically opaque ocular media using ultrasound is discussed. Optical coherence tomography and colour flow mapping are briefly described. Images of tomograms, B-mode sections, and colour flow maps illustrate the use of these techniques in imaging the vitreous
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    20. Imaging treated brain aneurysms in vivo using optical coherence tomography

      Jianping Su, Marlon S. Mathews, Chiedozie I. Nwagwu et al. Angiography is currently used to assess post-treatment human brain aneurysm healing, which can reveal vessel shape only. Optical coherence tomography (OCT) can reveal the vessel wall structure with high resolution, which has the advantage to assess vessel healing progress. An OCT endovascular cathet ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 684732 (2008)] published Mon Feb 18, 2008.
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    3841-3864 of 4007 « 1 2 ... 158 159 160 161 162 163 164 ... 165 166 167 »
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