1. Articles in category: Cardiology

    3817-3840 of 3851 « 1 2 ... 157 158 159 160 161 »
    1. Re-entry catheter

      Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other ...
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      Mentions: LuMend, Inc.
    2. Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery

      A method including positioning a catheter at a location in a blood vessel; imaging a thickness of a portion of a wall of the blood vessel at the location; identifying a treatment site; advancing a needle a distance into the wall of the blood vessel to the treatment site; and introducing a treatment agent through the needle to the treatment site. A composition including an inflammation-inducing agent and a carrier in the form of microspheres having a particle size suitable for transvascular delivery. A composition including a therapeutic angiogenesis promoter in a carrier and an opsonin-inhibitor coupled to the carrier ...
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    3. Intra vascular imaging apparatus

      An invasive imaging apparatus comprising: a flexible catheter with a proximal end and a distal end, the distal end being shaped for insertion into a blood vessel along a guide wire thereby to reach remote places in the vasculature or other organs, an optical assembly positioned at the distal end of the catheter comprising an image sensor positioned non-perpendicularly to the longitudinal axis of the catheter and an illumination sensor, at least one illumination source for illuminating an immediate region beyond the distal end of the catheter, and at least one working channel running from the proximal to the distal ...
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    4. Intravascular Optical Coherence Tomography Opens a Window onto Coronary Artery Disease

      Intravascular Optical Coherence Tomography Opens a Window onto Coronary Artery Disease
      In the United States alone, more than 650,000 people die each year of heart attacks related to coronary artery disease. A new technique, intravascular optical coherence tomography, may play an important role in guiding therapeutic interventions, diagnosing atherosclerosis and researching the causes of coronary artery disease.
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    5. Myocardial revascularization-optical reflectance catheter and method

      A myocardial revascularization device has a catheter suitable for use in a myocardial revascularization procedure, the catheter including an elongate body having a proximal end and a distal end, and tissue-ablating means housed at least partially within the catheter and capable of effectuating tissue ablation adjacent the distal end of the catheter. The device further has an optical reflectance fiber housed within the catheter and coupled to an optical reflectance system. The device is operative to transmit a reflectance signal in the optical reflectance fiber, the reflectance signal including either short optical pulses or low-coherence light. The optical reflectance system ...
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    6. Apparatus and methods for material capture and removal

      Catheters, kits, and methods are provided for removing material from a body lumen. The catheters and methods may be used in a variety of body lumens, including but not limited to coronary and other arteries. In general, the catheter has a cutting element that cuts material while the material is engaged by a material capture device on the catheter body. Preferably, the material capture device tensions the material during cutting, which reduces the amount of cutting force required. The material capture device typically follows a path that draws material into the catheter body. Preferably, but not necessarily, the material capture ...
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    7. Systems and methods for visualizing tissue during diagnostic or therapeutic procedures

      A catheter tube carries an imaging element for visualizing tissue. The catheter tube also carries a support structure, which extends beyond the imaging element for contacting surrounding tissue away from the imaging elements, the imaging element being movable with the support structure. The support element stabilizes the imaging element, while the imaging element visualizes tissue in the interior body region. The support structure also carries a diagnostic or therapeutic component to contact surrounding tissue.
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    8. Methods and apparatus for treating vascular occlusions

      Methods and apparatus for crossing totally to substantially occluded blood vessels by passing a redirectable wire such as a guidewire from a relatively proximal point past the occlusion within a subintimal space formed between the intimal layer and the adventitial layer of a blood vessel wall. The wire may be advanced to a point distal to the occlusion, and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. The deflecting catheter may include a flapper valve assembly or preformed actuator wire ...
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      Mentions: LuMend, Inc.
    9. Vascular re-entry catheter

      Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other ...
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      Mentions: LuMend, Inc.
    10. Imaging apparatus and method

      An apparatus and method for determining angular position of a sensor within a catheter. The invention is particularly useful for imaging devices delivered to a body lumen by a catheter, as may be the case for IVUS imaging catheters. The apparatus consists of a catheter having an inner core with an imaging sensor disposed within an inner diameter of a sheath of the catheter. The sheath is also provided with an outer diameter which has a center which it does not share with a center of the inner diameter. As a result, the catheter has a wall of non-uniform thickness ...
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    11. Ultra-small optical probes, imaging optics, and methods for using same

      Ultra-small optical probes comprising a single-mode optical fiber and a lens which has substantially the same diameter as the optical fiber. The optical fiber and lens are positioned in a probe housing which is in the form of an insertional medical device such as a guidewire. Connector elements are provided to facilitate the attachment of the probe to an optical system and the quick disconnection of the probe from the optical system. The probe is used to obtain optical measurements in situ in the body of an organism and can be used to guide interventional procedures by a surgeon.

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    12. Catheter system for treating a vascular occlusion

      A catherer system and method are provided including a blunt end assembly with a catheter and a blunt end member. The blunt end member includes jaw sections which have a first position or closed position for locating the blunt end member at the site of the occlusion within the native lumen of the blood vessel and a second position or open position wherein the jaw sections are able to press against the interior walls of the lumen adjacent the occlusion. The assembly includes an actuation member for moving the jaw sections from the closed to the open positions repeatedly resulting ...
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      Mentions: LuMend, Inc.
    13. Catheter guided by optical coherence domain reflectometry

      A guidance and viewing system based on multiplexed optical coherence domain reflectometry is incorporated into a catheter, endoscope, or other medical device to measure the location, thickness, and structure of the arterial walls or other intra-cavity regions at discrete points on the medical device during minimally invasive medical procedures. The information will be used both to guide the device through the body and to evaluate the tissue through which the device is being passed. Multiple optical fibers are situated along the circumference of the device. Light from the distal end of each fiber is directed onto the interior cavity walls ...
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    14. Intraluminal fiber-optic Doppler imaging catheter for structural and functional optical coherence tomography

      We describe a miniature fiber-optic Doppler imaging catheter for integrated functional and structural optical coherence tomography (OCT) imaging. The Doppler catheter can map blood flow within a vessel as well as image vessel wall structures. A prototype Doppler catheter has been developed and demonstrated for measuring the intraluminal velocity profile in a vessel phantom (conduit). A simple mathematical model is demonstrated to estimate the total flow rate. This estimation technique also enables the spatial range of flow measurements to be extended by approximately two times the normal OCT image-penetration depth. The Doppler OCT catheter could be a powerful device for ...
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    15. Optical focusing, collimating and coupling systems for use with single mode optical fiber

      Coupling devices for coupling a lens to a single mode optical fiber are disclosed. In one aspect, a lens alignment assembly is the coupling device and includes a single mode optical fiber, a lens, and a locating tube. The locating tube includes a hollow bore having an internal diameter such that the lens and single mode optical fiber are held in a tight, sliding fit within the locating tube. In another aspect, the device includes a single mode optical fiber located adjacent to a cylindrically shaped lens. The lens includes an angled facet having a reflective surface for directing light ...
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    16. Guidewire and catheter with rotating and reciprocating symmetrical or asymmetrical distal tip

      A guidewire or a catheter for crossing vascular occlusions comprises a shaft having a proximal end and a distal end, and a drive member having a proximal and a distal end, the drive member being rotatably disposed within and along a longitudinal axis of the guidewire shaft. An actuator is connected to the proximal end of the drive member, the actuator imparting a rotation to the drive member. An asymmetrical rotating tip is attached to the distal end of the drive member and driven in rotation about the longitudinal axis of the shaft by the drive member. The rotating tip ...
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      Mentions: LuMend, Inc.
    17. Apparatus for crossing total occlusion in blood vessels

      Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other ...
      Read Full Article
      Mentions: LuMend, Inc.
    18. Methods and apparatus for crossing total occlusions in blood vessels

      Total occlusions are crossed by passing a guidewire or other penetrating wire from a point proximal to the occlusion into a subintimal space between the intimal layer and adventitial layer of the blood vessel wall. The wire is advanced to a point distal to the occlusion and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. After the guidewire is returned to the blood vessel lumen, the deflecting catheter may be withdrawn and the guidewire is available for introduction of other ...
      Read Full Article
      Mentions: LuMend, Inc.
    19. Methods and apparatus for crossing vascular occlusions

      Methods and apparatus for crossing totally to substantially occluded blood vessels by passing a redirectable wire such as a guidewire from a relatively proximal point past the occlusion within a subintimal space formed between the intimal layer and the adventitial layer of a blood vessel wall. The wire may be advanced to a point distal to the occlusion, and thereafter deflected back into the blood vessel lumen, typically using a deflecting catheter which is advanced over the guidewire after it has been positioned within the subintimal space. The deflecting catheter may include a flapper valve assembly or preformed actuator wire ...
      Read Full Article
      Mentions: LuMend, Inc.
    20. Guidewire and catheter with rotating and reciprocating symmetrical or asymmetrical distal tip

      A guidewire or a catheter for crossing vascular occlusions comprises a shaft having a proximal end and a distal end, and a drive member having a proximal and a distal end, the drive member being rotatably disposed within and along a longitudinal axis of the guidewire shaft. An actuator is connected to the proximal end of the drive member, the actuator imparting a rotation to the drive member. An asymmetrical rotating tip is attached to the distal end of the drive member and driven in rotation about the longitudinal axis of the shaft by the drive member. The rotating tip ...
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      Mentions: LuMend, Inc.
    21. Optical coherence domain reflectometry guidewire

      A guidewire with optical sensing capabilities is based on a multiplexed optical coherence domain reflectometer (OCDR), which allows it to sense location, thickness, and structure of the arterial walls or other intra-cavity regions as it travels through the body during minimally invasive medical procedures. This information will be used both to direct the guidewire through the body by detecting vascular junctions and to evaluate the nearby tissue. The guidewire contains multiple optical fibers which couple light from the proximal to distal end. Light from the fibers at the distal end of the guidewire is directed onto interior cavity walls via ...
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    22. Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope

      Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
      An imaging system for performing optical coherence tomography includes an optical radiation source; a reference optical reflector; a first optical path leading to the reference optical reflector; and a second optical path coupled to an endoscopic unit. The endoscopic unit preferably includes an elongated housing defining a bore; a rotatable single mode optical fiber having a proximal end and a distal end positioned within and extending the length of the bore of the elongated housing; and an optical system coupled to the distal end of the rotatable single mode optical fiber, positioned to transmit the optical radiation from the single ...
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    3817-3840 of 3851 « 1 2 ... 157 158 159 160 161 »
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