1. Articles in category: Cardiology

    1-24 of 2378 1 2 3 4 ... 97 98 99 »
    1. Identification of vessel wall degradation in ascending thoracic aortic aneurysms with OCT

      Identification of vessel wall degradation in ascending thoracic aortic aneurysms with OCT

      Degradation of the wall of human ascending thoracic aorta has been assessed through Optical Coherence Tomography (OCT). OCT images of the media layer of the aortic wall exhibit micro-structure degradation in case of diseased aortas from aneurysmal vessels. The OCT indicator of degradation depends on the dimension of areas of the media layer where backscattered reflectivity becomes smaller due to a disorder on the morphology of elastin, collagen and smooth muscle cells (SMCs). Efficient pre-processing of the OCT images is required to accurately extract the dimension of degraded areas after an optimized thresholding procedure. OCT results have been validated against ...

      Read Full Article
    2. Measurement of the blood flow rate and velocity in coronary artery stenosis using intracoronary frequency domain optical coherence tomography: Validation against fractional flow reserve

      Measurement of the blood flow rate and velocity in coronary artery stenosis using intracoronary frequency domain optical coherence tomography: Validation against fractional flow reserve

      Objectives The main objective of this study was to assess the blood flow rate and velocity in coronary artery stenosis using intracoronary frequency domain optical coherence tomography (FD-OCT). A correlation between fractional flow reserve (FFR) and FD-OCT derived blood flow velocity is also included in this study. Methods & Results A total of 20 coronary stenoses in 15 patients were assessed consecutively by quantitative coronary angiography (QCA), FFR and FD-OCT. A percutaneous coronary intervention (PCI) optimization system was used in this study which combines wireless FFR measurement and FD-OCT imaging in one platform. Stenoses were labelled severe if FFR ≤ 0.8 ...

      Read Full Article
    3. Outcomes of everolimus-eluting stent incomplete stent apposition: a serial optical coherence tomography analysis

      Outcomes of everolimus-eluting stent incomplete stent apposition: a serial optical coherence tomography analysis

      Aim The aim of the present study was to evaluate the natural course of acute incomplete stent apposition (ISA) after second-generation everolimus-eluting stent (EES) when compared with first-generation sirolimus-eluting stent (SES) by using optical coherence tomography (OCT). Methods and results From the OCT substudy of the RESET trial, we identified 77 patients (EES = 38 and SES = 39) who successfully underwent serial OCT examination at post-stenting and 8–12-month follow-up. The presence of ISA was assessed in the OCT images, and ISA distance was measured from the centre of the strut blooming to the adjacent lumen border. Incomplete stent apposition was ...

      Read Full Article
    4. Optical coherence tomography investigation of ischemic stroke inside a rodent model

      Optical coherence tomography investigation of ischemic stroke inside a rodent model

      Although already in use in several medical domains, only recently optical coherence tomography (OCT) has been applied in the study of ischemic events. In this paper, we will focus on characterizing ischemic stroke, in a rat model, by OCT. Investigations were carried on a set of 25 rats, on which ischemic stroke was inflicted by a transient occlusion of the middle cerebral artery (tMCAO). Animals were sacrificed 1, 3, 7 and 28 days after occlusion. We tested the OCT’s power of detection and discrimination of stroke area compared to both normal, contralateral hemisphere and non-affected brain tissue, together with ...

      Read Full Article
    5. Very late neoatherosclerotic plaque rupture in drug-eluting stent restenosis

      Very late neoatherosclerotic plaque rupture in drug-eluting stent restenosis

      A 71-year-old man presented in emergency department for non-ST-elevation myocardial infarction. At admission, 12-lead ECG was in sinus rhythm without sign of myocardial ischemia, and troponin slightly increased. The only notable feature of the patient's medical history was single-vessel coronary artery disease revealed 10 years previously, treated by stenting of the second segment of the right coronary artery with a 3.0 x 25 mm bare metal stent. Three months later, intrastent restenosis was managed by implantation of a 3.0 x 28 mm paclitaxel-eluting stent. Two years before the present admission, following a non contributive stress test for ...

      Read Full Article
    6. Optical Coherence Tomography Guided Percutaneous Coronary Intervention With Stent Implantation

      Optical Coherence Tomography Guided Percutaneous Coronary Intervention With Stent Implantation

      Coronary artery disease is one of the most prevalent diseases in the western countries. A waxy substance called plaque can build up inside the coronary arteries. Over time, plaque can harden or rupture, and cause narrowing (stenosis) of the arteries and reduce the flow of oxygen-rich blood to the heart. The standard treatment of symptomatic coronary stenosis is percutaneous coronary intervention (PCI) with balloon dilation followed by stent implantation. A stent is a small metallic grid that stabilizes the coronary vessel wall after the balloon dilation. Currently, drug-eluting stents (DES) are the most widely used stent types. DESs consist of ...

      Read Full Article
    7. Comparison of Circulating Dendritic Cells and Monocyte Subsets at Different Stages of Atherosclerosis: insights from optical coherence tomography

      Comparison of Circulating Dendritic Cells and Monocyte Subsets at Different Stages of Atherosclerosis: insights from optical coherence tomography

      Objectives Proinflammatory dendritic cells (DC) and monocytes are critically involved in the proceeding and destabilization of atherosclerosis. Recent studies have reported potential associations of specific patterns of circulating DCs and monocytes with the incidence of coronary artery disease (CAD) and ST-elevation myocardial infarction (STEMI); however, further information of DC and monocyte subsets on plaque morphology and vulnerability is uncertain and required. Methods Forty-seven CAD patients with borderline lesions (stenosis 50%-70%) by coronary angiography (CAG) were enrolled, while 31 subjects free of luminal diameter narrowing ≥ 50% served as controls. Likewise, 35 patients with STEMI were enrolled and confirmed with the ...

      Read Full Article
    8. The Role of Multimodality Imaging Approach in Diagnosis and Stratification of Aborted Sudden Cardiac Death

      The Role of Multimodality Imaging Approach in Diagnosis and Stratification of Aborted Sudden Cardiac Death

      A 34-year-old man was admitted after an episode of aborted SCD. The initial investigation including electrocardiogram, chest X-ray, transthoracic echocardiogram and biomarkers were normal. Although coronary angiography showed non-severe stenosis, optical coherence tomography revealed severe obstruction in the artery with a layered appearance of the vessel wall; it was consistent with the presence of mural thrombus.

      Read Full Article
    9. Progress of Intravascular Optical Coherence Tomography Image Technology and Vascular Three-Dimensional Reconstruction

      Progress of Intravascular Optical Coherence Tomography Image Technology and Vascular Three-Dimensional Reconstruction

      Intravascular optical coherence tomography (IV-OCT) is a new intervention imaging technology for the diagnosis of coronary heart disease. Because of its high-resolution and non-invasive characteristics, it is widely used in clinical medicine. It has a revolutionary impact on coronary artery disease diagnosis, prognosis and treatment decisions. This paper studied this hot topic, gave the basic concepts of intravascular OCT image sequences. In accordance with current development studies, the key technology for three-dimensional reconstruction of the coronary vascular system is proposed and analyzed. On this basis, we proposed future research directions on IV-OCT vascular three-dimensional reconstruction, including clinical trial frequency domain ...

      Read Full Article
    10. Optical Coherence Tomography (OCT) Findings of Coronary Computed Tomography Angiography (CTA) Detected Vulnerable Plaque

      Optical Coherence Tomography (OCT) Findings of Coronary Computed Tomography Angiography (CTA) Detected Vulnerable Plaque

      Background: Recently, coronary computed tomography angiography (CTA) findings of positive vessel remodeling (PR) and low-attenuation plaque (LAP) have been reported to be associated with the development of acute coronary syndromes (ACS). The aim of this study was to examine the CTA detected vulnerable plaque characteristics by using intracoronary optical coherence tomography (OCT). Method and Result: A total of 16 patients with 16 lesions underwent PCI by using intracoronary OCT, after coronary CTA examination, were enrolled in this study. The CTA detected vulnerable plaque (CT-VP) was defined as LAP (<30 hounsfield unit (HU)) with PR of at least 110%. The lesions ...

      Read Full Article
    11. Longitudinal necrotic shafts near TCFAs—A potential novel mechanism for plaque rupture to trigger ACS?

      Longitudinal necrotic shafts near TCFAs—A potential novel mechanism for plaque rupture to trigger ACS?

      It has been questioned for over 15 years why only less than 20% of TCFAs trigger ACS. We illustrate TCFA rupture into adjacent longitudinal necrotic shafts of massive amounts of thrombogenic material into the blood, leading to catastrophic clot formation. This is the potential mechanism for TCFAs triggering ACS. One case presented also illustrates the dangers of stent edges rupturing TCFAs.

      Read Full Article
    12. Spontaneous coronary artery dissection: a case series and literature review

      Spontaneous coronary artery dissection: a case series and literature review

      Spontaneous coronary artery dissection (SCAD) is a rare and often lethal cause of acute coronary syndrome, which typically affects young women and otherwise healthy individuals. SCAD can be diagnosed in patients undergoing coronary angiography and can be underestimated. Special techniques such as optical coherence tomography (OCT) and intravascular ultrasound should be used when there is suspicion of the condition. In the majority of cases, the left anterior descending (LAD) artery is involved; however, a few cases of the right coronary artery (RCA) involvement have been reported. This article describes three cases of SCAD in women of different ages, all presenting ...

      Read Full Article
    13. Follow up evaluation of unapposed bioresorbable vascular scaffold at a coronary bifurcation using optical coherence tomography

      Follow up evaluation of unapposed bioresorbable vascular scaffold at a coronary bifurcation using optical coherence tomography

      The acute and long term performance of bioresorbable scaffolds (BVS) in treating ostial or bifurcation coronary lesions has not been established. In particular, treatment of these lesions presents the potential problems of non-apposition of struts proximal to the ostium of the vessel or in side branches. Data is also lacking as to whether additional scaffolds can be delivered through struts into side branches for two stent approaches to bifurcations. Despite this there have very few reports of any adverse consequences resulting from their use in these lesions.

      Read Full Article
    14. Bioresorbable vascular scaffold treatment induces the formation of neointimal cap that seals the underlying plaque without compromising the luminal dimensions: a concept based on serial optical coherence tomography data

      Bioresorbable vascular scaffold treatment induces the formation of neointimal cap that seals the underlying plaque without compromising the luminal dimensions: a concept based on serial optical coherence tomography data

      Aims: To evaluate the implications of an Absorb bioresorbable vascular scaffold (Absorb BVS) on the morphology of the superficial plaques. Methods and results: Forty-six patients who underwent Absorb BVS implantation and 20 patients implanted with bare metal stents (BMS) who had serial optical coherence tomographic examination at baseline and follow-up were included in this analysis. The thin-capped fibroatheromas (TCFA) were identified in the device implantation regions and in the adjacent native coronary segments. Within all regions, circumferential locations of TCFA and calcific tissues were identified, and the neointimal thickness was measured at follow-up. At six to 12-month follow-up, only 8 ...

      Read Full Article
    15. Serial Changes of Neointimal Tissue after Everolimus-Eluting Stent Implantation in Porcine Coronary Artery: An Optical Coherence Tomography Analysis

      Serial Changes of Neointimal Tissue after Everolimus-Eluting Stent Implantation in Porcine Coronary Artery: An Optical Coherence Tomography Analysis

      Purposes . The serial changes in neointimal tissues were compared between everolimus-eluting stent (EES) and bare-metal stent (BMS) in the porcine coronary artery using optical coherence tomography (OCT). Methods . Serial (1, 3, and 6 month follow-up after stent implantation) OCT examinations were performed in 15 swine with 15 BMS- and 15 EES-treated lesions in porcine coronary arteries. Results . In BMS-implanted lesions, neointimal volume decreased from 7.3 mm 3 to 6.9 mm 3 and 6.4 mm 3 at 1, 3, and 6 months follow-up without statistical significance ( ). At the time points of 1, 3, and 6 months, neointimal tissue ...

      Read Full Article
    16. Serum Cystatin C Level Not Associated with Coronary Artery Plaque Vulnerability Analyzed by Optical Coherence Tomography

      Serum Cystatin C Level Not Associated with Coronary Artery Plaque Vulnerability Analyzed by Optical Coherence Tomography

      Objectives Cystatin C, which is an endogenous marker for renal function, is reported to be a novel marker for coronary atherosclerosis. Some studies showed that lower cystatin C levels may be associated with increased severity of CAD in clinically stable patients, whereas higher levels may indicate the presence of any vulnerable plaque. To evaluate the relationship of Serum Cystatin C level and the coronary artery plaque vulnerability assessed by OCT in patients with coronary artery disease. Methods Eighty-two patients with chest pain underwent OCT assessment after coronary angiogram, all the lesions with diameter stenosis ≥30% and <100% were analyzed. The ...

      Read Full Article
    17. Volcano Corp Banks on IVUS Portfolio amid Several Odds - Analyst Blog

      Volcano Corp Banks on IVUS Portfolio amid Several Odds - Analyst Blog

      On Oct 10, we issued an updated research report on leading precision guided therapy tools provider, Volcano Corporation ( VOLC ). The company retains its position as a leader in the intravascular ultrasound (:IVUS) markets of U.S., Japan and Europe and holds 50% of the global market share.However, the current market environment remains challenging for Volcano. The final reimbursement reduction in Japan led to an approximate 5% cut in Imaging Disposables and an about 2% cut in fractional flow reserve ( FFR ) disposables of Volcano Corporation. These reimbursement cuts will be in effect for the next two years. In addition, the ...

      Read Full Article
    18. Epicardial Coronary Artery Compression Secondary to Pericardial Adhesions Demonstrated by Multi-Modality Imaging, and Treated by Coronary Stenting

      Epicardial Coronary Artery Compression Secondary to Pericardial Adhesions Demonstrated by Multi-Modality Imaging, and Treated by Coronary Stenting

      A 42-year-old female presented with sudden onset severe left-sided chest pain radiating to the left arm while watching a movie at home. She was rushed to the hospital within 10 minutes. She was found having ST elevation myocardial infarction on ECG and ventricular fibrillation arrest 2 times requiring cardiac resuscitation and defibrillation. Retrospectively, the patient recalled some ill-defined episodes of chest pain with exercise in the past few months before the admission. Her past surgical history 20 years previous was significant for video-assisted thoracoscopic surgery and pericardial window for removal of large, nonhemorrhagic pericardial effusion of 1.2 L, which ...

      Read Full Article
    19. Coronary artery wall imaging

      Coronary artery wall imaging

      Like X-Ray contrast angiography, MR coronary angiograms show the vessel lumens rather than the vessels themselves. Consequently, outward remodeling of the vessel wall, which occurs in subclinical coronary disease before luminal narrowing, cannot be seen. The current gold standard for assessing the coronary vessel wall is intravascular ultrasound, and more recently, optical coherence tomography, both of which are invasive and use ionizing radiation. A noninvasive, low-risk technique for assessing the vessel wall would be beneficial to cardiologists interested in the early detection of preclinical disease and for the safe monitoring of the progression or regression of disease in longitudinal studies ...

      Read Full Article
    20. Cardiologists at Chennai hospital combine two latest techniques to treat heart block

      Cardiologists at Chennai hospital combine two latest techniques to treat heart block

      A team of cardiologists at Apollo Hospitals in Chennai have combined two imaging techniques to get a better understanding of blocks formed within the heart blood vessels. Using latest imaging techniques like Fractional Flow Reserve (FFR) and Optical Coherence Tomography (OCT), the team found that a block in a patient had naturally recanalized and had multiple branches. The findings that were published in the Journal of American College of Cardiology highlights the case of a middle aged woman in whom the block was shown as mild in a regular angiogram.

      Read Full Article
    21. Delayed coverage of drug-eluting stents after interventional revascularisation of chronic total occlusions assessed by optical coherence tomography: the ALSTER-OCT-CTO registry - See more at: http://www.pcronline.com/eurointervention/ahead_of_print/201410

      Delayed coverage of drug-eluting stents after interventional revascularisation of chronic total occlusions assessed by optical coherence tomography: the ALSTER-OCT-CTO registry - See more at: http://www.pcronline.com/eurointervention/ahead_of_print/201410

      Aims: Following percutaneous coronary interventions (PCI) for revascularisation of chronic total occlusions (CTO) patients are at increased risk for stent thrombosis (ST). Delayed drug-eluting stent (DES) coverage has previously been shown to be related to ST. Using optical coherence tomography (OCT), we tested the hypothesis that CTO-PCI is associated with delayed DES coverage compared to non-CTO lesions. Methods and results: From 06/2010 to 11/2013, 105 patients (111 lesions) with clinically driven follow-up angiography after PCI with DES received an OCT analysis. Patients with successful CTO-PCI (19 patients/20 lesions, 6.5±2.1 months post PCI) were included ...

      Read Full Article
    1-24 of 2378 1 2 3 4 ... 97 98 99 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (2 articles) Kobe University Graduate School of Medicine
    2. (2 articles) Erasmus University
    3. (1 articles) University of Cantabria
    4. (1 articles) Samsung
    5. (1 articles) National Institutes of Health
    6. (1 articles) National University of Ireland, Galway
    7. (1 articles) University of Padova
    8. (1 articles) Massachusetts Institute of Technology
    9. (1 articles) Kawasaki Medical School
    10. (1 articles) University of Texas Health Science Center
    11. (1 articles) Hanyang University
    12. (1 articles) Brigham and Women’s Hospital
  4. People in the News

    1. (2 articles) Toshiro Shinke
    2. (2 articles) Hector M. Garcia-Garcia
    3. (1 articles) Christos V. Bourantas
    4. (1 articles) Yasushi Ino
    5. (1 articles) Takashi Akasaka
    6. (1 articles) Michael W. Jenkins
    7. (1 articles) Mark E. Brezinski
    8. (1 articles) Jung-Sun Kim
    9. (1 articles) Yangsoo Jang
    10. (1 articles) Myeong-Ki Hong
    11. (1 articles) Dong Hoon Choi
    12. (1 articles) Takashi Kubo
  5. OCT Companies in the News

    1. (1 articles) Volcano Corporation