1. Articles in category: Patents

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    1. Subtractive en face optical coherence tomography imaging

      Subtractive en face optical coherence tomography imaging

      En face or 3D volumetric OCT imaging during ophthalmic surgery may be performed with an OCT scanning controller that interfaces to an OCT scanner used with a surgical microscope. The OCT scanner may generate en face images before and after surgical operations, such as retinal membrane peeling, are performed. Using digital subtraction on the en face images, an overlay image indicative of the changes from the surgical operations to the eye may be generated and overlaid onto an optical image displayed to a user of the surgical microscope.

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      Mentions: Lingfeng Yu
    2. Ophthalmologic information processing apparatus and ophthalmologic information processing method

      Ophthalmologic information processing apparatus and ophthalmologic information processing method

      An ophthalmologic information processing apparatus for performing follow-up of a subject eye based on plural pieces of OCT data obtained at different dates includes: a processor; and memory storing computer readable instructions, when executed by the processor, causing the ophthalmologic information processing apparatus to execute: a first acquisition process of acquiring plural pieces of layer thickness information regarding a fundus, the plural pieces of layer thickness information being a processing result of the plural pieces of OCT data of the subject eye; a matching process of matching the pieces of layer thickness information based on the plural pieces of OCT ...

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      Mentions: Nidek
    3. System and method for providing surgical guidance based on polarization-sensitive optical coherence tomography

      System and method for providing surgical guidance based on polarization-sensitive optical coherence tomography

      Systems and methods are provided for identifying a suitable surgical location and/or trajectory for proceeding with a surgical procedure based on local polarization-sensitive optical coherence tomography imaging (PS-OCT). PS-OCT images are obtained of a tissue region and are processed to provide a spatial map of anisotropic structure within the tissue region. The anisotropic structure is processed to determine one or more suitable surgical locations and/or trajectories for avoiding or reducing damage to local anisotropic tissue structure identified within the tissue region. The spatial map of the anisotropic structure is registered with pre-operative volumetric image data identifying anisotropic tissue ...

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    4. Method and system for three-dimensional imaging

      Method and system for three-dimensional imaging

      A method for three-dimensional imaging stores a first image of field of view from a handheld optical coherence tomography (OCT) scanning device at a first position where a first OCT scan of an object is captured with the scanning device freely operated by a user. A location metric of a second image of field of view of the scanning device is estimated at a second position relative to the first image while the scanning device is moved from the first to the second position. Instructions on providing user feedback are generated based on the location metric. Feedback is provided to ...

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    5. Method and system for optically evaluating drilling proximity to the inferior alveolar nerve in situ

      Method and system for optically evaluating drilling proximity to the inferior alveolar nerve in situ

      A low coherence interferometry probe system for evaluating proximity to a tissue layer, comprising a low coherence light source for generating low coherence excitation light, an excitation optical fiber to bring the low coherence excitation light near the tissue layer and a collection optical fiber for capturing back-scattered light from the tissue layer. The probe system comprises a low coherence interferometry sub-system and a digital signal processor for evaluating a distance to the tissue layer. There is also provided a spectral absorption probe system for evaluating proximity to an artery, comprising a light source excitation light having a wavelength adapted ...

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    6. Methods and apparatus for retina blood vessel assessment with OCT angiography

      Methods and apparatus for retina blood vessel assessment with OCT angiography

      A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.

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    7. Method and apparatus for OCT-based viscometry

      Method and apparatus for OCT-based viscometry

      Methods and apparatus for ascertaining a relative viscosity characterizing a fluid sample. The fluid sample is illuminated through a scattering membrane adjacent to the fluid with broadband radiation. Scattering from particles within the fluid sample characterized by a distribution of characteristic dimensions spanning at least two orders of magnitude is detected, generating a detector signal as a function of depth relative to a specified surface of the scattering membrane at a plurality of temporal delays. A cross-correlation function of at least one of amplitude, phase and intensity of a scattered optical field is derived for a plurality of depths relative ...

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    8. Method and apparatus for measuring and displaying dental plaque, gingiva, and alveolar bone

      Method and apparatus for measuring and displaying dental plaque, gingiva, and alveolar bone

      A method and an apparatus for measuring and displaying dental plaque are provided, and the method includes the steps of dividing near infrared light output from a light source into measurement light and reference light, applying the measurement light toward a tooth in an oral cavity and scanning the tooth with the measurement light, producing interference light from reflected light and back-scattered light from the tooth and the reference light, generating an optical coherence tomographic image based on a scattering intensity value of the interference light, extracting a dental plaque region having a specific scattering intensity value from the optical ...

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    9. Image processing apparatus, estimation method, system, and medium

      Image processing apparatus, estimation method, system, and medium

      The position of the fovea is estimated with high accuracy in a manner such that the thicknesses of a first region including at least a partial region of a region from the internal limiting membrane to the boundary between the external plexiform layer and the external granular layer and a second region including at least a partial region of a region from the boundary to the photoreceptor cell inner segment/outer segment junction are compared with each other, and the position of the fovea is estimated.

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    10. System and method for dynamic focus control

      System and method for dynamic focus control

      En face views of OCT volumes provide important and complementing visualizations of the retina and optic nerve head investigating biomarkers of diseases affecting the retina. We demonstrate the combination of real time processing of OCT volumetric data for axial tracking. In combination with a Controllable Optical Element (COE), this invention demonstrates acquisition, real time tracking, automated focus on depth resolved en face layers extracted from a volume, and focus stacked OCT volumes with high resolution throughout an extended depth range.

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    11. Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

      Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

      Disclosed herein are methods and systems for the identification and characterization of fluid accumulation in the retina using OCT imaging. The disclosed methods and systems are directed to the automated segmentation of retinal fluid using 2D or 3D structural OCT scan images. Approaches for visualization and quantification of both intraretinal and subretinal fluid are presented. Methods are also disclosed for using OCT angiography data to improve the quality of retinal fluid segmentation, and to provide combined visualization of fluid accumulation and retinal vasculature to inform clinical interpretation of results.

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    12. Supercontinuum light source comprising microstructured optical fiber

      Supercontinuum light source comprising microstructured optical fiber

      The invention relates to a microstructured optical fiber for generating supercontinuum light upon feeding of pump light. The light can be incoherent light. The microstructured optical fiber has a first section and a second section, where the first and second sections have one or more different features. The invention also relates to a supercontinuum source comprising a microstructured optical fiber according to the invention.

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      Mentions: NKT Photonics
    13. Optical coherence tomography for measurement on the retina

      Optical coherence tomography for measurement on the retina

      An optical coherence tomograph that provides wavelength tunable source radiation and an illumination and measurement beam path, a dividing element that divides source radiation into illumination radiation and reference radiation, and collects measurement radiation. The illumination and measurement beam path has scanner. A detection beam path receives measurement radiation and reference radiation and conducts them onto at least one flat panel detector in a superposed manner. A beam splitter separates the measurement radiation from the illumination radiation. The beam splitter conducts the separated measurement radiation to the detection beam path and sets the numerical aperture of the illumination of the ...

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    14. Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures

      Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures

      Exemplary apparatus and method can be provided for obtaining data regarding a plurality of samples. For example, using at least one arrangement, it is possible to receive interferometric information that is based on radiations provided from a reference and the samples that are provided in respective chambers. Alternatively and/or in addition, based on the interferometric information, it is possible to discriminate between agents to identify a particular agent that affects a particular function within at least one of the samples.

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    15. Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope

      Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope

      Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope are disclosed herein. According to an aspect, a system includes first and second eyepieces. The system includes a display having first and second display portions, configured to display first images in the first display portion, and configured to display second images in the second display portion. The first image and the second image are projected along a first pathway and a second pathway. The system includes a first optical element positioned to relay the first images into the first eyepiece. The system includes a second ...

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    16. Acquisition and analysis techniques for improved outcomes in optical coherence tomography angiography

      Acquisition and analysis techniques for improved outcomes in optical coherence tomography angiography

      Methods for improved acquisition and processing of optical coherence tomography (OCT) angiography data are presented. One embodiment involves improving the acquisition of the data by evaluating the quality of different portions of the data to identify sections having non-uniform acquisition parameters or non-uniformities due to opacities in the eye such as floaters. The identified sections can then be brought to the attention of the user or automatically reacquired. In another embodiment, segmentation of layers in the retina includes both structural and flow information derived from motion contrast processing. In a further embodiment, the health of the eye is evaluating by ...

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    17. Systems and methods to remove shadowgraphic flow projections in OCT angiography

      Systems and methods to remove shadowgraphic flow projections in OCT angiography

      Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset.

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    18. Distance, diameter and area determining device

      Distance, diameter and area determining device

      An elongated member such as a catheter that uses ultrasound or optical coherence tomography "OCT") technology to approximate the dimensions of a structure into which the catheter has been placed. The catheter includes multiple ultrasound transducers arranged in an annular or circumferential configuration on, embedded into or within the body of the elongated member so that distance measurements can be obtained between the elongated member and the wall of the immediately facing structure (e.g., a fluid-filled lumen). Utilizing these measurements, the present invention approximates for the physician the shape and size of the structure into which the elongated member ...

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    19. Integrated multimodality intravascular imaging system that combines optical coherence tomography, ultrasound imaging, and acoustic radiation force optical coherence elastography

      Integrated multimodality intravascular imaging system that combines optical coherence tomography, ultrasound imaging, and acoustic radiation force optical coherence elastography

      An integrated intraluminal imaging system includes an optical coherence tomography interferometer (OCT), an ultrasound subsystem (US) and a phase resolved acoustic radiation force optical coherence elastography subsystem (PR-RAF-OCE). The steps include performing OCT to generate a returned optical signal, performing US imaging to generate a returned ultrasound signal, performing PRARF-OCE to generate a returned PR-ARF-OCE signal by generating a amplitude modulated ultrasound beam or chirped amplitude modulated ultrasound beam to frequency sweep the acoustic radiation force, measuring the ARF induced tissue displacement using phase resolved OCT, and the frequency dependence of the PR-ARF-OCE signal, processing the returned optical signal, the ...

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    20. Method and system for characterising biological tissue

      Method and system for characterising biological tissue

      The present disclosure provides a method for characterizing a region of interest within or between biological tissue. The method comprises inserting at least a portion of a probe into the region of interest and directing electromagnetic radiation to the region of interest and receiving electromagnetic radiation from the region of interest using the probe in a direction that is transversal to a length of the probe. Further, the method comprises directing a fluid to the region of interest through a portion of the probe and analyzing received electromagnetic radiation.

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    21. Distance measuring device and method for measuring distances

      Distance measuring device and method for measuring distances

      A device for measuring a distance to an object comprises a beam splitter for splitting broadband coherent light emitted by a light source in measuring light which is guided through an object arm to the object to be measured and in reference light which is guided to a reference arm. The object arm includes a focusing optics with a focus movable along an optical axis of the object arm. The focusing optics comprises a movable optical element and is configured such that a movement of the movable optical element along the optical axis causes a higher movement of the focus ...

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    22. Optical probes with reflecting components for astigmatism correction

      Optical probes with reflecting components for astigmatism correction

      Some devices comprise a first light-guiding component, a second light-guiding component, a lens, an optical-correction component that has a reflecting surface that faces the lens, and a sheath, which causes astigmatism. The reflecting surface has an optical power on a first axis of two orthogonal axes, the optical power on the first axis compensates for the astigmatism, and the reflecting surface has a negligible optical power on a second axis of the two orthogonal axes. Also, the reflecting surface is configured to reflect light from the lens and redirect the reflected light through the sheath.

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    23. Frustrated total internal reflection fingerprint detector

      Frustrated total internal reflection fingerprint detector

      The device provides an optical coherence tomography system; a first bank of light emitting diodes emitting light centered about a first wavelength; a second bank of light emitting diodes, emitting light centered about a second wavelength; a prism, said prism including a first surface transmissive of the wavelength of the probe beam of the optical coherence tomography system, and a second surface which is also transmissive of the wavelength of the probe beam, and where the second is surface coated from a first edge to a midpoint so to be reflective of light at the first wavelength and transmissive of ...

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    24. Automated analysis of intravascular OCT image volumes

      Automated analysis of intravascular OCT image volumes

      This disclosure provides systems and methods to automatically classify stent struts as covered or uncovered and to measure the thickness of tissue coverage. As one example, the method includes storing three-dimensional image data acquired intravascularly via an optical coherence tomography (OCT) apparatus and detecting struts based on analysis of the image data. Image data corresponding to each of the detected struts is further analyzed automatically to compute an indication of tissue coverage for the stent.

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