1. Articles in category: Patents

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    1. Automated assessment of glaucoma loss from optical coherence tomography

      Automated assessment of glaucoma loss from optical coherence tomography

      Systems and methods for assessing glaucoma loss using optical coherence topography. One method according to an aspect comprises receiving optical coherence image data and assessing functional glaucoma damage from retinal optical coherence image data. In an aspect, the systems and methods can map regions and layers of the eye to determine structural characteristics to compare to functional characteristics.

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    2. High visibility endoprosthesis and method

      High visibility endoprosthesis and method

      An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.

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    3. Integrated OCT-refractometer system for ocular biometry

      Integrated OCT-refractometer system for ocular biometry

      A Slit-lamp-or-Microscope-Integrated-OCT-Refractometer system includes an eye-visualization system, configured to provide a visual image of an imaged region in an eye; an Optical Coherence Tomographic (OCT) imaging system, configured to generate an OCT image of the imaged region; a refractometer, configured to generate a refractive mapping of the imaged region; and an analyzer, configured to determine refractive characteristics of the eye based on the OCT image and the refractive mapping, wherein the refractometer and the OCT imaging system are integrated into the eye visualization system

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    4. Cardiovascular OCT image making method and method for detecting stents using thereof

      Cardiovascular OCT image making method and method for detecting stents using thereof

      A cardiovascular OCT image making method which reduces artifacts includes the steps of: inputting a cardiovascular OCT image; converting coordinates of the inputted OCT image into two-dimensional polar coordinates (.theta. and r); generating a brightness control function of the A-line direction based on the blood wall relative to each .theta. value; forming a brightness image in the A-line direction based on the blood wall depending on the brightness control function; and forming an OCT image of which brightness is controlled by the brightness image by applying the brightness image formed on the inputted OCT image.

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    5. OCT probe with pivoting fiber

      OCT probe with pivoting fiber

      An OCT probe for imaging patient tissue may include an actuation system arranged to displace an optical fiber within a cannula. The actuation system may include a driver actuatable to displace a portion of the optical fiber, with the driver acting in an angled direction relative to the axis of the cannula. The actuation system also may include a pivot feature operably engaged with the optical fiber in a manner permitting the optical fiber to pivot on the pivot feature when the driver actuates to displace the portion of the optical fiber.

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    6. Non-invasive method and apparatus for screening high-quality seeds

      Non-invasive method and apparatus for screening high-quality seeds

      Disclosed is a method and apparatus for the non-invasive selection of high-quality seeds, based on optical coherence tomography, by which pathogen-infected and pathogen-free seeds can be discriminated in a non-invasive manner. The apparatus is operated by the processes of scanning a seed of diagnostic interest in a non-invasive manner using an optical coherence tomographic unit; processing interference signals of the scanned tomographic images to produce tomographic image data of the seed of diagnostic interest; analyzing the tomographic image data; comparing the analyzed tomographic image data with preset reference tomographic image data; diagnosing the seed of diagnostic interest as a pathogen-infected ...

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    7. Establishing compatibility between two- and three-dimensional optical coherence tomography scans

      Establishing compatibility between two- and three-dimensional optical coherence tomography scans

      Advances in optical coherence tomography (OCT) have prompted a transition from time domain OCT, providing 2D OCT images, to spectral domain OCT, which has a 3D imaging capability. Yet conventional technology offers little toward the goal of inter-device compatibility between extant 2D OCT images and newer 3D OCT images for the same or comparable subjects, as in the context of ongoing monitoring the quantitative status of a patient's eyes. The inventive methodology is particularly useful to identify the scan location of tissue in a 2D OCT image within the 3D OCT volumetric data, thereby allowing clinicians to image a ...

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    8. Optical coherence tomography systems and methods with magnitude and direction tracking of transverse motion

      Optical coherence tomography systems and methods with magnitude and direction tracking of transverse motion

      An optical coherence tomography (OCT) system having magnitude and direction of motion detection has a light source, and a scanning system arranged in an optical path of the light source. The scanning system is configured to scan an illumination beam of light in a spatial pattern around each of a plurality of points of interest of an object under observation for a corresponding plurality of instants of time in which each of the plurality of points of interest are displaced from each other due to motion of at least one of the OCT system or the object under observation. The ...

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    9. Supercontinuum light source, a system and a method of measuring

      Supercontinuum light source, a system and a method of measuring

      A supercontinuum light source comprising an intermediate supercontinuum light source and a single mode coupling unit, an optical measurement system comprising such light source, as well as a method of measuring are described. The supercontinuum light source comprises a pulse frequency multiplier to increase the repetition rate and the single mode coupling unit is arranged to dampen and shape the spectrum from the intermediate supercontinuum light source to allow measurements with a reduced noise floor.

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      Mentions: NKT Photonics
    10. System and method for calibrated spectral domain optical coherence tomography and low coherence interferometry

      System and method for calibrated spectral domain optical coherence tomography and low coherence interferometry

      Systems and methods for enhancing spectral domain optical coherence tomography (OCT] are provided. In particular, a system and method for calibration of spectral interference signals using an acquired calibration signal are provided. The calibration signal may be logarithmically amplified to further improve the accuracy of the calibration. From the calibration signal, a series of more accurate calibration data are calculated. An acquired spectral interference signal is calibrated using these calibration data. Moreover, systems that include logarithmic amplification of the spectral interference signal and variable band-pass filtering of the spectral interference signal are provided. Such systems increase the dynamic range and ...

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    11. Method and system for optical coherence elastography of posterior parts of the eye

      Method and system for optical coherence elastography of posterior parts of the eye

      A system and method for optical coherence elastography of tissue of an eye. The method includes introducing a probe into the eye, the probe including a vibration element, generating time resolved images of the tissue of the eye located posterior the vibration element of the probe by optical coherence tomography, exciting the vibration element to ultrasonic vibrations making the tissue vibrate or oscillate, measuring a displacement of the tissue in the time resolved images, and calculating elasticity values of the tissue from the displacement.

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    12. Methods and systems for characterizing angle closure glaucoma for risk assessment or screening

      Methods and systems for characterizing angle closure glaucoma for risk assessment or screening

      A method is proposed for analyzing an optical coherence tomography (OCT) image of the anterior segment (AS) of a subject's eye. A region of interest is defined which is a region of the image containing the junction of the cornea and iris, and an estimated position the junction within the region of interest is derived. Using this a second region of the image is obtained, which is a part of the image containing the estimated position of the junction. Features of the second region are obtained, and those features are input to an adaptive model to generate data characterizing ...

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      Mentions: Tin Aung
    13. Scanning interferometry technique for through-thickness evaluation in multi-layered transparent structures

      Scanning interferometry technique for through-thickness evaluation in multi-layered transparent structures

      A multi-layer transparent composite detection technique includes producing two beams from a single, low-coherence source, a test beam and a reference beam, and scanning the reference beam to determine, with high precision, the depths of flaws (e.g., delaminations, bubbles, inclusions or other reflective or scattering objects) within a specimen or test object. The techniques combine light back-reflected or back-scattered from an internal flaw or interface with light in a reference path to identify such features and locations.

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    14. Dual focusing optical coherence imaging system

      Dual focusing optical coherence imaging system

      The present invention relates to a dual focusing optical coherence imaging system. The dual focusing optical coherence imaging system includes: a light source unit for generating broadband light; a main optical distributor for distributing the light generated from the light source to allow the light to be propagated; an interference unit including first and second interference parts for forming interference signals with respect to different focused areas of an object to be detected using the light distributed from the optical distributor, and a common sample arm commonly connected to the first and second interference parts; an optical switch connected to ...

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      Mentions: Korea University
    15. Optimized device for swept source optical coherence domain reflectometry and tomography

      Optimized device for swept source optical coherence domain reflectometry and tomography

      Optimized device for swept source optical coherence domain reflectometry and tomography. In the coherence-optical device, light, with the aid of an interferometer, is used for distance-measuring and imaging purposes on reflecting and scattering areas of the human eye. The optimized device according to the invention consists of includes a tunable light source, matched to the sought-after measurement region ZOCT, with a resonator length LR, an interferometric measurement arrangement, a data capturing unit for capturing the light portions scattered back from the sample and a data processing unit. Here the resonator length LR of the tunable light source is matched not ...

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    16. Optical coherence tomography-based ophthalmic testing methods, devices and systems

      Optical coherence tomography-based ophthalmic testing methods, devices and systems

      In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's/subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be ...

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    17. Test device for testing a bonding layer between wafer-shaped samples and test process for testing the bonding layer

      Test device for testing a bonding layer between wafer-shaped samples and test process for testing the bonding layer

      The invention relates to a test device for testing a bonding layer between wafer-shaped samples and a test process for testing the bonding layer. The test device comprises a measuring head for an OCT process that is configured to direct an optical measuring beam at a composite comprising at least two wafer-shaped samples with a bonding layer positioned between them. An optical beam splitter is configured to divert an optical reference beam as a reference arm for distance measurements. An evaluation unit is configured to evaluate layer thickness measurements without a reference arm and distance measurements with a reference arm ...

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    18. Coherence gated doppler motion sensor and medical applications

      Coherence gated doppler motion sensor and medical applications

      A motion sensor applicable to medical procedures includes a source of light with a wavelength bandwidth and an optical detector. A first optical coupler terminates in a first probe tip and couples the light into the first probe tip. A second optical coupler terminates in a second probe tip and directs onto the detector scattered light returning through the second probe tip. A presentation device outputs a signal that indicates motion in a target volume of a sample in a vicinity of the probe tips based on a Doppler shift of the scattered light. The volume depends on coherence distance ...

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    19. System and method for interlacing differing coherence length sweeps to improve OCT image quality

      System and method for interlacing differing coherence length sweeps to improve OCT image quality

      A system and method for sweeping electromagnetic radiation over a first coherence length and a second length over a range of wavelengths to generate an image. Electromagnetic radiation having a first coherence length is generated and swept over a range of wavelengths. Electromagnetic radiation having a second coherence length is generated and swept over a range of wavelengths. The electromagnetic radiation is splitting through a reference path and a sample path; Electromagnetic radiation returned from the reference path and the sample path is detected, wherein the detector generates output signals corresponding to the received electromagnetic radiation. In one embodiment, the ...

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    20. Optical property measurement apparatus and optical property measurement method

      Optical property measurement apparatus and optical property measurement method

      An apparatus enabling abnormality detection of a sample. A first interference optical system scans the sample with first signal light from a first sample optical path, making the first signal light interfere with first reference light from a first reference optical path, to detect first interference light. Optical path length difference between the first sample optical path and first reference optical path is changed based on the detection. A change in the optical path length difference is determined. A second interference optical system scans the sample with second signal light from a second sample optical path, making the second signal ...

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    21. Program for correcting data measured by PS-OCT and PS-OCT system equipped with the program

      Program for correcting data measured by PS-OCT and PS-OCT system equipped with the program

      Data measured by PS-OCT is corrected in a non-linear manner to enhance the quantitative analysis capability of PS-OCT and permit accurate quantitative diagnosis, including diagnosis of disease stage of lesions, as a useful means for computer diagnosis. Even when retardation per PS-OCT 1 contains error and becomes noise and its distribution is not normal or symmetrical around the true value, measured data is converted using a distribution conversion function obtained by analyzing the characteristics of noise via Monte Carlo simulation to remove the systematic error and estimate the true value otherwise buried in noise and thereby correct the PS-OCT 1 ...

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    22. Methods, systems and computer program products for dynamic optical histology using optical coherence tomography

      Methods, systems and computer program products for dynamic optical histology using optical coherence tomography

      Methods of acquiring an image are provided. The methods include deriving a first boundary surface from a volumetric image; deriving a second boundary surface, different and spaced apart from the first boundary surface, of the volumetric image, the first and second boundary surfaces defining a slice of the volumetric image therebetween; and deriving at least one intermediate thin section between the first and second boundary surfaces, the thin section having a thickness that is less than a thickness of the slice of the volumetric image defined by the first and second boundary surfaces. Systems and computer program products are also ...

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    23. Integrated optical coherence tomography systems and methods

      Integrated optical coherence tomography systems and methods

      Disclosed herein are optical integration technologies, designs, systems and methods directed toward Optical Coherence Tomography (OCT) and other interferometric optical sensor, ranging, and imaging systems wherein such systems, methods and structures employ tunable optical sources, coherent detection and other structures on a single or multichip monolithic integration. In contrast to contemporary, prior-art OCT systems and structures that employ simple, miniature optical bench technology using small optical components positioned on a substrate, systems and methods according to the present disclosure employ one or more photonic integrated circuits (PICs), use swept-source techniques, and employ a widely tunable optical source(s).

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      Mentions: Eric A. Swanson
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