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(28 articles) Massachusetts Institute of Technology
(16 articles) Massachusetts General Hospital
(13 articles) Harvard University
(12 articles) University of Texas at Austin
(10 articles) Russian Academy of Sciences
(9 articles) University of Washington
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Catheter for conducting a procedure within a lumen, duct or organ of a living being
Explore Article PatFT » Page 1 of 1 (Mar 9 2010) Cardiology , Patents
In an embodiment, the invention provides a catheter suitable for use in performing a procedure within a vessel, lumen or organ of a living having a distal end which is steerable, such as upon the application of compression. The catheter may be of the over the wire type, or alternatively may be a rapid exchange catheter. The catheter may provide for a rotating element which may be used to open a clogged vessel, or alternatively to provide information about adjacent tissues, such as may be generated by imaging or guiding arrangements using tissue detection systems known in the art, e.g., ...
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System and method for enhancing microscopic images of tissue
Explore Article PatFT » Page 1 of 1 (Mar 9 2010) Microscopy , Patents
A system and method for enhancing images of ex-vivo or in-vivo tissue produced by confocal microscopy, optical coherence tomography, two-photon microscopy, or ultrasound, is provided by applying to the tissue a solution or gel having an effective concentration of citric or other alpha-hydroxy acid which enhances tissue structures, such as cellular nuclei, in such images. Such concentration may be 3-20% acid, and preferably 5% acid. -
Apparatus For Optical Coherence Tomography And Non-Interferometric Imaging (Wo 2010/022915)
Explore Article wipo.int (Mar 4 2010) Patents
The invention relates to an apparatus for optical coherence tomography and non-interferometric imaging of a sample. Additional splitting optics are used to arrange off the light used for the non-interferometric imaging. Interrupting means are provided for interrupting light in the reference path during measurement with the non-interferometric imaging.
Comment on Article Mentions: Maciej Wojtkowski Nicolaus Copernicus University Optopol Technology
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High power broadband superluminescent diode
Explore Article PatFT » Page 1 of 1 (Mar 2 2010) Patents , Broadband Sources
A superluminescent diode according the present invention employs a uniform AlGaInAs quantum well on an InP substrate, emitting in a range of 1100 to 1800 nm. The favorable conduction band: valence band offset ratio of this material system enables superluminescent diodes which simultaneously provide high power and large optical bandwidth. A recent reduction to practice of the present invention simultaneously demonstrates output power exceeding 100 mW and bandwidth exceeding 100 nm. A preferred embodiment of this invention uses multiple uniform AlGaInAs quantum wells with two confined quantum states and energetic separation in a range of 100-130 nm. An alternate preferred ...
Comment on Article Mentions: Praevium Research Vijaysekhar Jayaraman
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System for identifying refractive-index fluctuations of a target
Explore Article PatFT » Page 1 of 1 (Feb 23 2010) Patents
Systems and methods for identifying refractive-index fluctuations of a target are described in this application. One embodiment includes identifying one or more properties of emergent light, the emergent light to be emergent from a target, and determining refractive-index fluctuations of the target based on the one or more properties of the emergent light. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation ...
Comment on Article Mentions: Northwestern University Vadim Backman
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Method of bioimage data processing for revealing more meaningful anatomic features of diseased tissues
Explore Article PatFT » Page 1 of 1 (Feb 23 2010) Patents
The present invention discloses a method for generating elevation maps or images of a tissue layer/boundary with respect to a fitted reference surface, comprising the steps of finding and segmenting a desired tissue layer/boundary; fitting a smooth reference surface to the segmented tissue layer/boundary; calculating elevations of the same or other tissue layer/boundary relative to the fitted reference surface; and generating maps of elevation relative to the fitted surface. The elevation can be displayed in various ways including three-dimensional surface renderings, topographical contour maps, contour maps, en-face color maps, and en-face grayscale maps. The elevation can also be combined and ...
Comment on Article Mentions: Scott A. Meyer Matthew J. Everett Carl Zeiss Meditec
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Imaging system with low coherence light source
Explore Article PatFT » Page 1 of 1 (Feb 23 2010) Patents
An imaging system uses a low coherence light source to image objects at a relatively far distance (at least 10 cm) and/or of a relatively large size (having a dimension of at least 10 cm). An imaging plane is located such that its image path is substantially equal to a reference path that the light follows within the imaging device. The imaging plane has a thickness of about the coherence length of the light. Only light returning from the imaging plane forms part of the image. Light returning on other paths is effectively negated due to a lack of coherence. ...
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Contactless Method Of Measuring The Density Of A Porous Material, Using A Measurement Of The Refractive Index Of The Material Obtained By Optical Coherence Tomography (Wo 2010/015594)
Explore Article wipo.int (Feb 11 2010) Patents
The contactless method of measuring the density of a porous material uses a measurement of the refractive index of the material obtained by optical coherence tomography. According to the invention, an optical coherence tomography technique is used to determine the optical path corresponding to the penetration through an object (20) made of the material by a light beam used in the technique; the thickness of the object is determined; the refractive index of the material is determined from the optical path and the thickness; and the density of the material is determined from the refractive index.
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Establishing Compatibility Between Two-And Three Dimensional Optical Coherence Tomography Scans (Wo 2010/017356)
Explore Article wipo.int (Feb 11 2010) Ophthalmology , Patents
Advances in optical coherence tomography (OCT) have prompted a transition from time domain OCT, providing 2D OCT images, to spectral domain OCT, which has a 3D imaging capability. Yet conventional technology offers little toward the goal of inter-device compatibility between extant 2D OCT images and newer 3D OCT images for the same or comparable subjects, as in the context of ongoing monitoring the quantitative status of a patient's eyes. The inventive methodology is particularly useful to identify the scan location of tissue in a 2D OCT image within the 3D OCT volumetric data, thereby allowing clinicians to image a patient ...
Comment on Article Mentions: University of Pittsburgh Joel S. Schuman Gadi Wollstein
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Method and device for wave-front sensing
Explore Article PatFT » Page 1 of 1 (Feb 9 2010) Patents
A method for sensing a wave-front of specimen light scattered from an illuminated area in a specimen (10) includes the steps of focusing illumination light into the specimen (10), directing specimen light scattered in the specimen (10) to a detector device (50) having a plurality of detector elements (51) and being capable to sense light with local resolution, detecting sample light contained in the specimen light with the detector device (50), said sample light being scattered in a predetermined sample plane (11) of the specimen (10) and being selected by a time-based gating of the specimen light, locally resolved measuring ...
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Colorimetric three-dimensional microscopy
Explore Article PatFT » Page 1 of 1 (Feb 9 2010) Microscopy , Patents
An optically reflective or translucent object (14) can be microscopically imaged in all three dimensions and in true color for observation by a human observer. An interferometric optical setup is employed, using the low temporal coherence of a tunable broad-band light source (10, 20) to resolve the axial dimension, a single opto-mechanical or electronic scanning mechanism for accessing different object depths, and a two-dimensional photo sensor device (15, 34) capable of demodulating the temporally or spatially modulated scanning signals to reconstruct the object's full volume. Three volume scans are carried out sequentially, and the tunable broad-band source (10, 20) is ...
Comment on Article Mentions: Heliotis AG
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Miniature actuator mechanism for intravascular imaging
Explore Article PatFT » Page 1 of 1 (Feb 9 2010) Cardiology , Patents , Probes
The present invention relates to a new intravascular imaging device based on a Shape Memory Alloy (SMA) actuator mechanism embedded inside an elongate member such as a guide wire or catheter. The present invention utilizes a novel SMA mechanism to provide side-looking imaging by providing movement for an ultrasound transducer element. This novel SMA actuator mechanism can be easily fabricated in micro-scale, providing an advantage over existing imaging devices because it offers the ability to miniaturize the overall size of the device, while the use of multiple transducer crystals maximizes field of view. Also disclosed are methods of using the ...
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Carl Zeiss Meditec and University of Miami sued Optovue over Patent Infringement
Explore Article Bloomberg.com (Feb 4 2010) Ophthalmology , Other Business News , Patents
Carl Zeiss Meditec AG (AFX GY): A unit of the maker of medical lasers to correct vision defects and the University of Miami sued California-based Optovue Inc. in federal court in Delaware over claims it infringed two patents for technology to map the eye.
Comment on Article Mentions: Optovue Carl Zeiss Meditec University of Miami
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Method for endoluminal imaging with movement correction
Explore Article PatFT » Page 1 of 1 (Feb 2 2010) Endoscopy , Patents
The present invention relates to a method for imaging using an image-generating, endoluminal instrument (1) by means of which a sequence of 2D image data of a hollow channel (2), in particular a vessel, of an object under investigation is recorded, wherein the images are recorded in a known temporal relation to a periodic movement of the object under investigation and spatial coordinates of the image are captured by means of a position sensor during each recording of an image (5) and stored as position data (9, 10) together with the 2D image data of the image (5). The method ...Comment on Article Mentions: Siemens
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Short-wavelength coherence tomography
Explore Article PatFT » Page 1 of 1 (Feb 2 2010) Patents
The present relates generally to methods, systems and apparatuses for three dimensional and cross-sectional imaging of objects (e.g., silicon) and subjects at a nanometer-scale resolution using short wave-length (e.g., extreme ultra-violet) light.Comment on Article Mentions: Texas A&M University








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