1. Articles in category: Patents

    1-24 of 2396 1 2 3 4 ... 98 99 100 »
    1. Systems and methods for retinal layer segmentation in OCT imaging and OCT angiography

      Systems and methods for retinal layer segmentation in OCT imaging and OCT angiography

      Disclosed herein are methods and systems for segmenting, visualizing, and quantifying the layered structure of retina in optical coherence tomography datasets. The disclosed methods have particular application to OCT angiography data, where specific retina layers have distinct vascular structures and characteristics that can be altered in various pathological conditions of the eye.

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    2. Associating optical coherence tomography (OCT) data with visual imagery of a sample

      Associating optical coherence tomography (OCT) data with visual imagery of a sample

      A multi-modal imaging and optical property measurement device that is integrated into an interferometer. Data acquired by the multiple imaging modalities in parallel include measurements of single-scattered, multiple-scattered, and diffuse light that enable characterization of different ranges within different depth regions in the sample. The system includes different interferometer configurations and different imaging modalities, and has a signal-processing unit that associates and co-registers interferometric, multi-spectral, and polarization sensitive measurements to derive and analyze optical properties of a sample and enhance an image display of the sample.

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    3. Optical coherence tomography imaging system

      Optical coherence tomography imaging system

      An imaging system, a method for imaging an object of interest, and an image of the object of interest. In one embodiment, an imaging system includes a channel configured to receive information from an object of interest, a 3DSS sub-system configured to capture information from the object of interest and generate at least one of 3D surface data or 3D position data based on the information captured by the 3DSS sub-system, and an OCT sub-system configured to perform a line scan of light reflected from the object of interest, generate OCT image data from the line scan, receive the at ...

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    4. Signal extraction systems and methods

      Signal extraction systems and methods

      Swept source optical coherence tomography (SS-OCT) systems and methods may employ down-conversion. Down-converter systems and methods may utilize a distribution element and a frequency down shifter. The distribution element may receive an output signal of a photo detection device, the output signal comprising a first frequency component at or below a maximum conversion frequency and a second frequency component above the maximum conversion frequency. The distribution element may send the first frequency component to an analog to digital (A/D) converter and send the second frequency component to a frequency down shifter. The frequency down shifter may down shift the ...

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    5. Forward and side imaging optical coherence tomography probe

      Forward and side imaging optical coherence tomography probe

      A forward-imaging optical coherence tomography probe is provided, comprising: a substantially cylindrical housing comprising: a longitudinal axis; an interior side; a distal end that is optically transparent; and a mirror located at the interior side, adjacent the distal end; an optical fiber located inside the cylindrical housing along the longitudinal axis; a wedge lens located inside the cylindrical housing, adjacent the distal end, the wedge lens configured to receive light from the fiber, and direct the light towards the mirror; and, at least one motor configured to both: rotate the fiber and the wedge lens about the longitudinal axis and ...

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    6. Selective amplification of optical coherence tomography signals

      Selective amplification of optical coherence tomography signals

      Presented is an optical coherence tomography system and method to increase imaging depth of optical coherence tomography (OCT) by selective amplification. In a swept-source OCT system with periodically linear wavenumber-vs-time characteristic, the signal in principle is summation of various sinusoidal signals with different frequencies. Each frequency component of the recorded signal carries reflectivity information for a certain depth of the analyzed object. At greater depth inside the analyzed object, the reflectivity information is generally weak due absorption and scattering. An analog or digital electronic circuit selectively filters and amplifies frequencies above some threshold, possibly up to another threshold. In this ...

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    7. Distributed delay-line for low-coherence interferometry

      Distributed delay-line for low-coherence interferometry

      A Time Domain Optical Coherence Tomography system using a modulation scheme multiplexes the scanning range of the delay line into different spectral bands. Such a modulation scheme may allow for power consumption reduction compared with a single delay line element since the same modulation pattern is being used for several channels. In an example, the optical coherence tomography system may include a plurality of stages, each stage having a group delay element. The distinct group delays may be introduced to scan a sample with distinct electrical frequency bands at distinct axial scanning depth ranges.

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    8. Radiofrequency ablation catheter with optical tissue evaluation

      Radiofrequency ablation catheter with optical tissue evaluation

      Systems and methods for performing RF ablation while monitoring the procedure using low coherence interferometry (LCI) data are described. A catheter includes a distal section, a proximal section, a multiplexer, and a sheath coupled between the distal section and the proximal section. The distal section includes several interconnected optical ports configured to transmit exposure radiation toward a sample and receive radiation that have been reflected or scattered from the sample. The interconnected optical ports are formed on a substrate having rigid sections and flexible sections arranged around the distal section. A holder maintains the interconnected optical elements in a fixed ...

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    9. OCT system with bonded MEMS tunable mirror VCSEL swept source

      OCT system with bonded MEMS tunable mirror VCSEL swept source

      A microelectromechanical systems (MEMS)-tunable vertical-cavity surface-emitting laser (VCSEL) in which the MEMS mirror is bonded to the active region. This allows for a separate electrostatic cavity that is outside the laser's optical resonant cavity. Moreover, the use of this cavity configuration allows the MEMS mirror to be tuned by pulling the mirror away from the active region. This reduces the risk of snap down. Moreover, since the MEMS mirror is now bonded to the active region, much wider latitude is available in the technologies that are used to fabricate the MEMS mirror. This is preferably deployed as a ...

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    10. Ophthalmic imaging apparatus and ophthalmic information processing apparatus

      Ophthalmic imaging apparatus and ophthalmic information processing apparatus

      An ophthalmic imaging apparatus of an embodiment includes a measurement unit, an eye model generation unit, and a simulation execution unit. The measurement unit is configured to acquire a data set by applying optical coherence tomography to a three-dimensional region of a subject's eye including an area extending from an anterior surface of a cornea to a surface of a retina. The eye model generation unit is configured to acquire values of one or more parameters of the subject's eye by analyzing the data set acquired by the measurement unit, and to generate a three-dimensional eye model based ...

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    11. Intravascular imaging system interfaces and stent detection methods

      Intravascular imaging system interfaces and stent detection methods

      The disclosure relates, in part, to computer-based visualization of stent position within a blood vessel. A stent can be visualized using intravascular data and subsequently displayed as stent struts or portions of a stent as a part of a one or more graphic user interface(s) (GUI). In one embodiment, the method includes steps to distinguish stented region(s) from background noise using an amalgamation of angular stent strut information for a given neighborhood of frames. The GUI can include views of a blood vessel generated using distance measurements and demarcating the actual stented region(s), which provides visualization of ...

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    12. Light source and optical coherence tomography apparatus including the light source

      Light source and optical coherence tomography apparatus including the light source

      A light source includes an upper electrode layer, a lower electrode layer, and an active layer interposed therebetween. At least one of the upper and lower electrode layers is divided into a plurality of electrodes separated from each other in an in-plane direction of the active layer. The separated electrodes independently inject current into a plurality of different regions in the active layer. The light source emits light by injecting current from the upper and lower electrode layers into the active layer, guide the light in the in-plane direction, and output the light. The plurality of different regions in the ...

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    13. Method and apparatus for motility contrast imaging

      Method and apparatus for motility contrast imaging

      A system for motility contrast imaging a biological target within tissue comprising a CCD array; an illumination source for generating an incoming beam; a first beam splitter for receiving the incoming beam and producing an object beam and a reference beam; a second beam splitter for illuminating a multitude of biological targets with the object beam and for directing backscattered object beams towards the CCD array; a computer-controlled delay stage for zero-path-matching the reference beam to the backscattered object beams; a reference beam that intersects the backscattered object beams at an angle to produce a series of interference fringes that ...

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    14. OCT apparatus

      OCT apparatus

      An OCT apparatus includes: a light source unit that includes first and second wavelength sweeping light sources which sequentially emit light with first and second spectrum bandwidths; an SS-OCT optical system that splits the light into measurement light and reference light to receive interference signal light; a second detector that is a deviation detector detecting a phase deviation and a wavelength deviation and detects a signal including pieces of FPN; a calculation processor connecting first and second spectrum interference signals and processes the connected spectrum interference signals to acquire an OCT image and that obtains the phase deviation and the ...

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      Mentions: Nidek
    15. Early prediction of age related macular degeneration by image reconstruction

      Early prediction of age related macular degeneration by image reconstruction

      An AMD prediction model utilizes an OCT image estimation model. The OCT image estimation module is created by segmenting an OCT image to generate an OCT projection image for each of multiple biological layers; extracting from each of the generated OCT projection images a first set of features; extracting a second set of features from an input retinal fundus image; for each respective biological layer, registering the input retinal fundus image to the respective OCT projection image by matching at least some of the second set of features with corresponding ones of the first set of features; repeating the above ...

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    16. System for optical coherence tomography, comprising a zoomable kepler system

      System for optical coherence tomography, comprising a zoomable kepler system

      The invention relates to an optical system for examining an eye by means of optical coherence tomography. The OCT system is designed in such a way that at least a first and a second state of the optical system can be selectively set by controlling the variable optical unit. In the first state, the OCT measurement beam has a measurement focus at an object distance from the objective, wherein the object distance has a value between 50 millimeters and 400 millimeters. In the second state, the measurement beam has defocusing at the same object distance, wherein the defocusing corresponds to ...

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    17. Method and system for motion artefacts removal in optical coherence tomography

      Method and system for motion artefacts removal in optical coherence tomography

      A method and system for compensating for motion artefacts in Optical Coherence Tomography is provided. A B-scan set includes a plurality of B-scan images acquired at least a position corresponding to a target position of a fundus of an eye. The plurality of B-scans within the B-scan set are aligned using a first alignment process and a second alignment process, where the second alignment process is performed on the B-scan images within the B-scan set aligned by the first alignment process. The first alignment process aligns the B-scan images within the B-scan set at a first resolution in at least ...

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    18. Binocular en face optical coherence tomography imaging

      Binocular en face optical coherence tomography imaging

      Binocular en face OCT imaging during ophthalmic surgery may be performed with an OCT scanning controller that interfaces to an OCT scanner used with a surgical microscope. The OCT scanner may generate left and right sample beams, and receive left and right measurement beams, respectively, to generate left and right scan data. The OCT scanning controller may process the left and right scan data to generate left and right en face images for respective viewing from binoculars in the surgical microscope to obtain an intraoperative stereoscopic en face view of interior portions of the eye.

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    19. System for coregistration of optical coherence tomography and angiographic X-ray image data

      System for coregistration of optical coherence tomography and angiographic X-ray image data

      A system comprises a catheter including a lens, for acquiring optical coherence tomography images within the vessel of interest as the catheter is being retracted from the vessel in the presence of contrast agent. An X-ray imaging system interface receives a first set of X-ray images of an anatomical region including the vessel of interest containing the catheter. The first set of X-ray images are acquired at points corresponding to the particular points within a heart cycle, while the catheter is stationary in the vessel, in response to a heart electrical activity representative signal and in the absence of contrast ...

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      Mentions: Siemens
    20. Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography

      Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography

      Disclosed are devices and techniques based on optical coherence tomography (OCT) technology in combination with optical actuation. A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam into the OCT device which splits the OCT imaging beam into the optical sampling beam and the optical reference beam; and a light source that produces an optical actuation beam ...

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    21. Clinic evaluation via outer retinal layer assessment

      Clinic evaluation via outer retinal layer assessment

      Systems and methods are provided for evaluating an eye of a patient from a set of OCT data. A layer segmentation component is configured to identify and segment a plurality of retinal layers within the set of OCT data. The plurality of layers include a layer of interest. A mapping component is configured to generate at least one of an en face representation of the layer of interest and a three-dimensional reconstruction of the layer of interest from the segmented plurality of layers. A parameter generator is configured to derive at least one parameter, representing a thickness of the layer ...

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    22. Simultaneous imaging, monitoring, and therapy

      Simultaneous imaging, monitoring, and therapy

      Using the disclosed intravascular devices it is possible to image tissues, deliver therapy, and evaluate the tissue after the therapy is delivered. One embodiment is a catheter configured to provide ultrasound imaging, drug delivery, and Doppler flow analysis. The devices can use ultrasound imaging as well as optical coherence tomography (OCT).

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    1-24 of 2396 1 2 3 4 ... 98 99 100 »
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