1. Articles in category: Patents

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    1. Optical coherence tomography for performing measurements on the retina

      Optical coherence tomography for performing measurements on the retina

      An optical coherence tomography includes a wavelength tunable illuminating device, an illumination and measurement beam path with a dividing element and a scanner and a front optical unit and a reference beam path, a detection beam path and a flat panel detector. A beam splitter conducts the separated measurement radiation to the detection beam path and an optical element acts only on the illumination radiation. The optical element sets the numerical aperture of the illumination of the illumination field in the eye. An optical element acts only on the measurement radiation and sets the numerical aperture with which measurement radiation ...

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    2. Optical coherence tomography device for otitis media

      Optical coherence tomography device for otitis media

      An OCT apparatus and method for characterization of a fluid adjacent to a tympanic membrane has a low coherence source which is coupled to a splitter which has a measurement path and a reference path. The reference path is temporally modulated for length, and the combined signals from the reference path and the measurement path are applied to a detector. The detector examines the width of the response and the time variation when an optional excitation source is applied to the tympanic membrane, the width of the response and the time variation forming a metric indicating the viscosity of a ...

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    3. Systems and methods for improved OCT measurements

      Systems and methods for improved OCT measurements

      Various systems and methods for sequential angle illumination to achieve ultra-high resolution optical coherence tomography (OCT) images. One example OCT system includes a light source, a beam divider, sample arm optics, a detector, and a processor. The light source generates a light beam to illuminate the sample. The beam divider separates the light beam into reference and sample arms. The sample arm optics sequentially illuminates a location in the sample with the light beam from different angles. The detector receives light returned from the reference arm and the sample illuminated at each angle and generates signals. The processor combines the ...

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    4. Optical coherence tomography systems and methods with dispersion compensation

      Optical coherence tomography systems and methods with dispersion compensation

      An optical coherence tomography (OCT) interferometer includes at least a first optical fiber of a first type having a first length, in series with a second optical fiber of a second type which is different than the first type and having a second length, in at least one of the sample path and/or the reference path of the OCT interferometer. The dispersion characteristics of the first optical fiber and the second optical fiber are significantly different than each other. As a result, the total group delay dispersion of a first portion of the laser light passing through the sample ...

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    5. Probe, optical coherence tomography device, and zero point correction method

      Probe, optical coherence tomography device, and zero point correction method

      A probe (1) is used in an optical coherence tomography device which irradiates measurement light to a subject and collects scattered light that has returned from the subject after being reflected. The probe (1) is provided with a scanning means (70) composed of galvanometer mirrors (72, 73) that change an irradiation direction of the measurement light. The scanning means (70) is provided with actuators (72b, 73b) which switch reflecting mirrors (72a, 73a) that reflect the measurement light between a state where the measurement light is reflected by the subject and returns as the scattered light, and a state where the ...

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    6. Image processing apparatus, image processing method, and program

      Image processing apparatus, image processing method, and program

      An image processing apparatus is disclosed, which uses OCT to process a plurality of cross-sectional images obtained by moving an imaging core inside a catheter in an axial direction while rotating the imaging core. Cross-sectional image data is acquired in association with position information in the axial direction when each of the cross-sectional images. A first cross-sectional image in which a disappearance section enabling determination having a disappeared portion of an external elastic membrane included in a vascular tomographic image starts, and a second cross-sectional image in which the disappearance section ends are extracted from the plurality of cross-sectional images ...

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    7. Dynamic mode switching for multi-mode ophthalmic optical coherence tomography

      Dynamic mode switching for multi-mode ophthalmic optical coherence tomography

      Techniques and apparatus for selectively producing half-depth and full-depth OCT images, based on a swept-source OCT interference signal. An example method comprises selecting from a first sampling rate and a second sampling rate, the second sampling rate being twice the first sampling rate, and sampling the swept-source Optical Coherence Tomography (OCT) interference signal at the selected sampling rate, using a k-clock signal having a frequency range corresponding to the first sampling rate, to produce a sampled OCT interference signal. The method further comprises processing the sampled OCT interference signal to obtain an OCT image, such that the resulting OCT image ...

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    8. MEMS tunable VCSEL powered swept source OCT for 3D metrology applications

      MEMS tunable VCSEL powered swept source OCT for 3D metrology applications

      Disclosed is an optical probe system that is capable of high speed, high precision, and high resolution 3D digitalization of engineered objects. The 3D dimensional data of the engineered object is measured using a swept source optical coherence tomography system with improved speed, spatial resolutions, and depth range. Also disclosed is a type of coordinate measurement machine (CMM) that is capable of performing high speed, high resolution, and non-contact measurement of engineered objects. The mechanic stylus in the touch-trigger probe of a conventional CMM is replaced with an optical stylus with reconfigurable diameter and length. The distance from the center ...

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    9. Balloon atherectomy catheters with imaging

      Balloon atherectomy catheters with imaging

      An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body and an imaging shaft connected to the imaging element and extending within the catheter body. The cutter and the imaging element are mechanically isolated, and the drive shaft is configured to be axially translated relative to the imaging shaft and the catheter body.

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    10. Optical coherence elastography (OCE) method under acoustic radiation force excitation using OCT doppler variance methods and OCT correlation-based methods

      Optical coherence elastography (OCE) method under acoustic radiation force excitation using OCT doppler variance methods and OCT correlation-based methods

      A system for imaging and quantifying shear wave and shear modulus under orthogonal acoustic radiation force (ARF) excitation using the OCT Doppler variance apparatus. The ARF perpendicular or with at least a perpendicular component to the OCT beam is produced by a remote ultrasonic transducer. The OCT Doppler variance apparatus, which is sensitive to the transverse vibration, is used to measure the ARF induced vibration. For analysis of the shear modulus, the Doppler variance apparatus is utilized to visualize shear wave propagation. The propagation velocity of the shear wave is measured and then used to quantitatively map the shear modulus.

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    11. Optical coherence tomographic imaging based image processing apparatus and image processing method for imaging object at a plurality of times at different focus positions

      Optical coherence tomographic imaging based image processing apparatus and image processing method for imaging object at a plurality of times at different focus positions

      An image processing apparatus of the invention is for generating a tomographic image corresponding to a cross-section of an imaging object. The image processing apparatus 1 comprises: a data acquisitor 20 which obtains image data corresponding to a plurality of imaging with respect to the imaging object; and an image generator 30 which generates the tomographic image corresponding to the cross-section parallel to the depth direction based on the image data. The plurality of imaging are performed with mutually different focus positions in a depth direction and imaging ranges overlapped in the depth direction. The image generator 30 sets a ...

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    12. Multichannel optical receivers

      Multichannel optical receivers

      Methods and apparatus are presented for multichannel optical coherence tomography. Light from a wavelength tuneable or steppable optical source is separated into one or more sample beams and one or more reference beams, and the one or more sample beams directed onto a sample to form one or more interaction regions. A plurality of returning probe beams are collected and mixed with the one or more reference beams to form an interference pattern comprising a plurality of interferograms having at least two distinct carrier frequencies. The multichannel optical apparatus can be provided with polarisation discrimination by mixing the returning probe ...

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      Mentions: Cylite
    13. Guidewire detection systems, methods, and apparatuses

      Guidewire detection systems, methods, and apparatuses

      In part, the disclosure relates to methods of guidewire detection in intravascular data sets such as scan lines, frames, images and combinations thereof. Methods of generating one or more indicia of a guidewire in a representation of blood vessel are also features of the disclosure. A carpet view is generated in one embodiment and regions of relatively higher contrast are detected as candidate guidewire regions. In one embodiment, the disclosure relates to selective removal of guidewire segments from a set of intravascular data and the display of a representation of a blood vessel via a user interface. Representations of a ...

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      Mentions: Abbot
    14. System and method for characterizing tissue organization using polarization sensitive optical coherence tomography

      System and method for characterizing tissue organization using polarization sensitive optical coherence tomography

      Abstract A system and method for characterizing tissue organization using polarization sensitive optical coherence (PSOCT) tomography is provided. A PSOCT device is controlled, by a computing device, to obtain PSOCT A-line scans across a sample. For each of the PSOCT A-line scans, the computing device determines a frequency characteristic of any banding present in a respective PSOCT A-line retardance scan. The computing device controls display device to render a map of the frequency characteristic.

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    15. Methods and systems for OCT guided glaucoma surgery

      Methods and systems for OCT guided glaucoma surgery

      Disclosed herein are systems and methods for aiding a surgeon to perform a surgical procedure on an eye. The surgical procedure includes inserting an elongate probe from an opening into the eye across an anterior chamber to a target tissue region comprising a trabecular meshwork and a Schlemm's canal. Exemplary systems include an optical microscope for the surgeon to view the eye with a microscope image during the procedure; an optical coherence tomography (OCT) apparatus configured to perform an OCT scan of a target location in the target tissue region during the procedure; and an image processing apparatus configured ...

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    16. Optical coherence tomography for orthodontic aligners

      Optical coherence tomography for orthodontic aligners

      Methods and apparatuses for 3D imaging (including 3D optical coherence tomography imaging) to measure the shape of orthodontic aligners, teeth, and other oral structures simultaneously, in-vivo or in-vitro. These methods and apparatuses may be used to determine contact locations of aligners with teeth and/or teeth with other teeth with very high precision, including determining the size of gaps where they are not in contact. These measurements may be used design, modify or replace an aligner and/or to verify aligner fit. 3D models of the whole aligner and teeth may be generated.

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    17. Optical imaging and measurement systems and methods for cataract surgery and treatment planning

      Optical imaging and measurement systems and methods for cataract surgery and treatment planning

      An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

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    18. Systems and methods for variable-range fourier domain imaging

      Systems and methods for variable-range fourier domain imaging

      An optical system includes a light source, an interferometer, and a detector. The interferometer includes a scanner and a lens system disposed downstream of the scanner. The scanner is configured to direct a portion of the optical beam along one of a plurality of different directions within a scanning range. The lens system is configured to project the portion of optical beam to an imaging area defined by a field of view of the optical system, the lens system comprising a first lens, wherein an aspect of the first lens is adjustable so as to render the field of view ...

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    19. Methods, systems and apparatus for temporal calibration of an intravascular imaging system

      Methods, systems and apparatus for temporal calibration of an intravascular imaging system

      In part, the disclosure relates to systems for imaging a blood vessel using intravascular image data and extravascular image data and methods to calibrate such systems. In one embodiment, multiple calibration trials are performed to determine a plurality of time lag values. A minimum time lag value is used to align intravascular image data and extravascular time lag data in one embodiment.

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      Mentions: Desmond C. Adler
    20. Efficient sampling of optical coherence tomography data for explicit ranging over extended depth

      Efficient sampling of optical coherence tomography data for explicit ranging over extended depth

      An efficient OCT data collection and processing method for obtaining a high-axial-resolution image with explicit ranging over an extended depth is described. The method includes collecting a first dataset at a transverse location of the sample. The first dataset comprises spectra of a bandwidth (.DELTA.k.sub.1) sampled at a spectral sampling interval (dk.sub.1). A second dataset comprising spectra of a bandwidth (.DELTA.k.sub.2) sampled at a spectral sampling interval (dk.sub.2) is collected. The bandwidth .DELTA.k.sub.2 is less than .DELTA.k.sub.1 and spectral sampling interval dk.sub.2 ...

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    21. Apparatus and methods for optical coherence tomography and two-photon luminescence imaging

      Apparatus and methods for optical coherence tomography and two-photon luminescence imaging

      Exemplary embodiments of the present disclosure include a combined catheter-based optical coherence tomography-two-photon luminescence (OCT-TPL) imaging system. Exemplary embodiments further include methods to detect, and further characterize the distribution of cellular components (e.g., macrophage, collagen/elastin fiber, lipid droplet) in thin-cap fibroatheromas with high spatial resolution in vivo.

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    22. System and method for imaging subsurface of specimen

      System and method for imaging subsurface of specimen

      There is a need for robust and portable system, apparatus and method for imaging subsurface of specimens. We have described a modular OCDR-OCT system and OFDR-OCT system to obtain high quality images. The instant application also discusses proprietary algorithms that have been modified from existing algorithms and their use as a combination to suit a particular system. The imaging of stationary, moving and combination of both subsurface structures such as retina for diabetic patients is described.

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    23. Quantification of local circulation with OCT angiography

      Quantification of local circulation with OCT angiography

      Impaired intraocular blood flow within vascular beds in the human eye is associated with certain ocular diseases including, for example, glaucoma, diabetic retinopathy and age-related macular degeneration. A reliable method to quantify blood flow in the various intraocular vascular beds could provide insight into the vascular component of ocular disease pathophysiology. Using ultrahigh-speed optical coherence tomography (OCT), a new 3D angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) was developed for imaging microcirculation within different intraocular regions. A method to quantify SSADA results was developed and used to detect perfusion changes in early stage ocular disease. Associated embodiments relating to methods ...

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    24. Optical coherence tomography (OCT) system having integrated detector and analysis systems

      Optical coherence tomography (OCT) system having integrated detector and analysis systems

      An optical detector system comprises a hermetic optoelectronic package, an optical bench installed within the optoelectronic package, a balanced detector system installed on the optical bench. The balanced detector system includes at least two optical detectors that receive interference signals. An electronic amplifier system installed within the optoelectronic package amplifies an output of at least two optical detectors. Also disclosed is an integrated optical coherence tomography system. Embodiments are provided in which the amplifiers, typically transimpedance amplifiers, are closely integrated with the optical detectors that detect the interference signals from the interferometer. Further embodiments are provided in which the interferometer ...

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    1-24 of 2558 1 2 3 4 ... 105 106 107 »
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