1. Articles in category: Patents

    1-24 of 2209 1 2 3 4 ... 90 91 92 »
    1. Methods and systems for performing angle-resolved Fourier-domain optical coherence tomography

      Methods and systems for performing angle-resolved Fourier-domain optical coherence tomography

      Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third ...

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    2. Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis

      Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis

      This invention discloses methods and systems for measuring corneal epithelial thickness and power, stromal thickness, subepitheila corneal power and topography. The systems and methods disclosed herein are non-invasive, non-contact and automated imaging methods which preferably makes use of Fourier-domain optical tomography. Also disclosed herein are scanning patterns and image analysis methods for utilizing and analyzing Fourier-domain optical coherence tomography images to obtain information about conical epithelial and stromal properties as well as parameters useful for evaluating the properties. The methods and systems described herein are useful as eye disease diagnostic tools and eye surgery planning tools.

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    3. OCT probe with bowing flexor

      An OCT probe includes a cannula and includes a selectively displaceable light-carrying optical fiber disposed within the cannula. The optical fiber may be arranged to emit light from a distal end thereof. A flexor may be bent to divide the flexor into a first segment and a second segment extending along a lumen of the cannula. The first segment may be coupled to the optical fiber. A driver may be configured to push or pull the second segment in the axial direction to elastically bow the second segment and laterally displace the optical fiber to perform an OCT scan.

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    4. Combined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue

      Combined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue

      A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path.

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    5. Resolution enhancement of OCT images during vitreoretinal surgery

      Resolution enhancement of OCT images during vitreoretinal surgery

      Resolution enhancement of OCT images during ophthalmic surgery may be performed with an OCT scanning controller that interfaces to an OCT scanner used with a surgical microscope. Real-time OCT images may be acquired by the OCT scanner, while previously acquired high resolution OCT images are accessed by the OCT scanning controller. The high resolution OCT images may be morphed based on the real-time OCT images to match a deformation of the eye. The morphed high resolution OCT images may be displayed during surgery.

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    6. Control method of a fundus examination apparatus

      Control method of a fundus examination apparatus

      A control method of a fundus examination apparatus constructed as a perimeter for examining a fundus of an examinee's eye, includes: controlling a monitor provided in the fundus examination apparatus as the perimeter to display a two-dimensional map pertinent to a two-dimensional analysis result of the fundus based on a tomographic image of the examinee's eye obtained by an optical coherence tomography device; setting an examination position in the fundus examination apparatus as the perimeter on the two-dimensional map displayed on the monitor; and controlling the fundus examination apparatus as the perimeter based on the set examination position ...

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    7. Device for reliably determining biometric measurement variables of the whole eye

      Device for reliably determining biometric measurement variables of the whole eye

      A device for determining biometric variables of the eye, as are incorporated in the calculation of intraocular lenses including a multi-point keratometer and an OCT arrangement. The keratometer measurement points are illuminated telecentrically and detected telecentrically and the OCT arrangement is designed as a laterally scanning swept-source system with a detection region detecting the whole eye over the whole axial length thereof. The multi-point keratometer ensures that a sufficient number of keratometer points are available for measuring the corneal surface. By contrast, telecentricity ensures that the positioning inadequacies of the measuring instrument in relation to the eye to be measured ...

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    8. Optical probe for optical coherence tomography and manufacturing method therefor

      Optical probe for optical coherence tomography and manufacturing method therefor

      To provide an optical probe for OCT and a method of manufacturing the optical probe that can reduce reflected light generated at a boundary portion between an optical fiber and a lensed fiber. An optical probe for OCT includes an optical fiber that transmits irradiation light and back-scattered light and a lensed fiber that is fusion spliced to an end face of the optical fiber, that emits irradiation light toward the inside of a living body while collimating the irradiation light, and that collects and guides back-scattered light to the end face of the optical fiber. A refractive index adjusting ...

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    9. Systems and methods for spectrally dispersed illumination optical coherence tomography

      Systems and methods for spectrally dispersed illumination optical coherence tomography

      Systems and methods are presented for acquisition and processing of spectrally dispersed illumination optical coherence tomographic data. Light from a source is distributed spectrally on the sample, and each acquisition simultaneously provides partial spectral interference information from multiple locations in the sample. Thus for a given spatial point, a single observation will be of a partial spectrum A-scan. When multiple partial spectrum A-scan observations are made at the same point by shifting the spectrum of light on to the tissue, the point can be observed by the entire broadband spectrum of the light source, thereby making it possible to create ...

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    10. Smart phone attachment for 3-D optical coherence tomography imaging

      Smart phone attachment for 3-D optical coherence tomography imaging

      Methods and apparatus for tomographic imaging of a sample. Low-coherence light is split into a sample path and a reference path. A steering optic recombines light in the reference path with light scattered by a sample onto a camera having an areal focal plane array of detector elements such that light in the reference path and light scattered by the sample are characterized by respectively offset propagation vectors at incidence upon the camera. A processor derives depth information from light scattered by the sample on the basis of interference fringes between light in the reference path and light scattered by ...

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    11. OCT image modification

      OCT image modification

      According to some examples, a method for Optical Coherence Tomography (OCT) image modification includes receiving an OCT image of a region of interest of patient tissue from an OCT imaging system configured to direct an OCT beam at the region of interest and determining that an OCT transparent instrument is within the OCT image. The method further includes detecting an artifact in the OCT image, the artifact resulting from the OCT transparent instrument being within a path of the OCT beam. In response to detecting the artifact, the method further includes creating an image modification plan to remove the artifact ...

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    12. Imaging system, method and distal attachment for multidirectional field of view endoscopy

      Imaging system, method and distal attachment for multidirectional field of view endoscopy

      An exemplary apparatus for imaging at least one anatomical structure can be provided. For example, the apparatus can include an endoscopic first arrangement, a radiation source second arrangement which provides at least one electro-magnetic radiation, and a third arrangement attached to at least one portion of the endoscopic arrangement. The third arrangement can contain an optical arrangement which, upon impact by the at least one electro-magnetic radiation and based thereon, may transmit a first radiation and reflects a second radiation. The first radiation can impact at least one first portion of the anatomical structure(s), and the second radiation can ...

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    13. System for eye examination by means of stress-dependent parameters

      System for eye examination by means of stress-dependent parameters

      The present disclosure relates to a system for examining an eye. The system comprises a microscopy system for generating an image plane image of an object region. An OCT system of the system is configured to acquire OCT data from the object region which reproduce the object region in different stress states. A data processing unit of the system is configured to determine at least one value of a stress-dependent parameter, depending on the OCT data. The system generates an output image that is dependent on the image plane image and is furthermore dependent on the stress-dependent parameter.

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    14. Apparatus and methods for identifying and evaluating bright spot indications observed through optical coherence tomography

      Apparatus and methods for identifying and evaluating bright spot indications observed through optical coherence tomography

      Exemplary embodiments of the present disclosure include apparatus and methods for identifying bright spot indications observed through optical coherence tomography. The indications can be evaluated, for example, to link risk factors or other conditions to clinically relevant outcomes

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    15. Optical coherence tomography with homodyne-phase diversity detection

      Optical coherence tomography with homodyne-phase diversity detection

      There is provided an optical tomographic observation device which has a resolving power which is higher than those of a conventional optical tomographic observation device and a confocal microscope by a simple configuration by applying a homodyne phase diversity detection technology and designing so as to satisfy the following formula when .lamda. is a wavelength of a laser light source, .DELTA..lamda. is a wavelength half width at half maximum, NA is a numerical aperture of an objective optical element, S is an effective area of a photodetector, and M is a detection magnification of a detection surface relative to ...

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    16. Interferometer, lithography apparatus, and method of manufacturing article

      Interferometer, lithography apparatus, and method of manufacturing article

      An interferometer includes: an optical system configured to generate interfering light by dividing light from a light source, and combining reference light and measurement light; a detector configured to detect the interfering light generated by the optical system; and an optical member configured to give spatial coherence to the light from the light source before the detector detects the light from the light source. The optical member gives higher spatial coherence in a second direction serving as a direction of a line of intersection of a cross section of a beam of the light incident on the optical member, and ...

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    17. Process for optical coherence tomography and apparatus for optical coherence tomography

      Process for optical coherence tomography and apparatus for optical coherence tomography

      In a process for optical coherence tomography a plurality of first OCT slice images, in each first slice image representing a different slice of an object, are recorded. Subsequently a reference figure that is representative of the three-dimensional contour of at least one structural feature of the object in a given three-dimensional coordinate system is ascertained by feature recognition of the at least one structural feature in the first slice images. Then a plurality of second OCT slice images, each second slice image representing a different slice of the object, are recorded. At least a fraction of the second slice ...

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    18. Optical coherence tomography imaging systems and methods

      Optical coherence tomography imaging systems and methods

      Optical coherence tomography imaging systems and methods are disclosed. According to an aspect, an optical coherence tomography imaging system includes a scanner configured to obtain images and to convert the images to electrical signals. The system also includes a computing device comprising an OCT module configured to receive the electrical signals, to apply an OCT imaging technique, and to generate imaging data.

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      Mentions: William J. Brown
    19. Devices, methods, and systems of functional optical coherence tomography

      Devices, methods, and systems of functional optical coherence tomography

      The present disclosure provides systems and methods for the determining a rate of change of one or more analyte concentrations in a target using non invasive non contact imaging techniques such as OCT. Generally, OCT data is acquired and optical information is extracted from OCT scans to quantitatively determine both a flow rate of fluid in the target and a concentration of one or more analytes. Both calculations can provide a means to determine a change in rate of an analyte over time. Example methods and systems of the disclosure may be used in assessing metabolism of a tissue, where ...

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    20. Measurement of the lipid and aqueous layers of a tear film

      Measurement of the lipid and aqueous layers of a tear film

      Systems and methods for determining thickness of lipid and aqueous layers of a tear film in which a spectrum array is generated from optical coherence tomography and input into a statistical estimator, which determines the thickness of the lipid and/or aqueous layers at a nanometer resolution based on the inputted spectrum and other information, such as information about a laser intensity noise, Poisson noise, and dark noise associated with the OCT.

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    21. Laser speckle microrheometer for measuring mechanical properties of biological tissue

      Laser speckle microrheometer for measuring mechanical properties of biological tissue

      Volumetric distribution of a micromechanical parameter of a biological tissue, such as viscoelastic parameter or tissue stiffness, is determined, with microscopic resolution, from optical data representing light scattered by sequential layers of the tissue and, optionally, displayed to visualization. A particular layer of the tissue is defined through coherence-gating of light received at the optical detector. Coherence-gating is achieved with the use of an interferometer the sample arm of which contains the tissue, illuminated with defocused light, and an optical length of a reference arm of which is repeatedly adjusted, within a coherence length of used light, to ensure that ...

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    22. Optical interference tomographic apparatus, and method for controlling optical interference tomographic apparatus

      Optical interference tomographic apparatus, and method for controlling optical interference tomographic apparatus

      In order to acquire a tomographic image of the eye to be inspected with high precision even in case where an optical path length and intensity vary depending on a scanned position in an OCT apparatus acquiring the tomographic image of a predetermined part of an object to be inspected, based on the intensity of interference light obtained by combining return light from the object that has been irradiated with the measuring light, with reference light corresponding to the measuring light, includes: a scanning optical system which scans the object with the measuring light in an optical path of the ...

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    23. Endoscopic biopsy apparatus, system and method

      Endoscopic biopsy apparatus, system and method

      Exemplary embodiments of apparatus, method and system for determining a position on or in a biological tissue can be provided. For example, using such exemplary embodiment, it is possible to control the focus of an optical imaging probe. In another exemplary embodiment, it is possible to implement a marking apparatus together with or into an optical imaging probe. According to one exemplary embodiment, it is possible (using one or more arrangements) to receive information associated with at least one image of at least one portion of the biological tissue obtained using an optical imaging technique. Further, it is possible to ...

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    24. Multimodal imaging system, apparatus, and methods

      Multimodal imaging system, apparatus, and methods

      In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L1 and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In ...

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    1-24 of 2209 1 2 3 4 ... 90 91 92 »
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