1. Articles in category: Patents

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    1. Volume analysis and display of information in optical coherence tomography angiography

      Volume analysis and display of information in optical coherence tomography angiography

      Computer aided visualization and diagnosis by volume analysis of optical coherence tomography (OCT) angiographic data. In one embodiment, such analysis comprises acquiring an OCT dataset using a processor in conjunction with an imaging system; evaluating the dataset, with the processor, for flow information using amplitude or phase information; generating a matrix of voxel values, with the processor, representing flow occurring in vessels in the volume of tissue; performing volume rendering of these values, the volume rendering comprising deriving three dimensional position and vector information of the vessels with the processor; displaying the volume rendering information on a computer monitor; and ...

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    2. System and method for intravascular structural analysis compensation of chemical analysis modality

      System and method for intravascular structural analysis compensation of chemical analysis modality

      A multimodal intravascular analysis uses a structural intravascular analysis modality to compensate for a chemical analysis modality. Examples of structural analysis are IVUS, OCT, including optical coherence domain Reflectometry (OCDR) and optical frequency domain imaging (OFDI), and/or sonar range finding. Examples of chemical or functional analysis are optical, NIR, Raman, fluorescence and spectroscopy, thermography and reflectometry. In one example, the structural analysis is used to characterize the environment structurally, such as catheter head-vessel wall distance. This information is then used to select from two or more algorithms which are depth specific (e.g. shallow vs. deep), to achieve improved ...

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      Mentions: InfraReDx
    3. Method for reducing the dimensionality of a spatially registered signal derived from the optical properties of a sample, and device therefor

      Method for reducing the dimensionality of a spatially registered signal derived from the optical properties of a sample, and device therefor

      At least one embodiment of the method is designed to create a two-dimensional image of a three-dimensional sample. The method comprises the following steps: provision of a wave-length-tunable light source (1) that emits primary radiation (P) with wavelengths that vary over time; sampling of location points of the sample (2) with the primary radiation (P); collection of secondary radiation (S), wherein the secondary radiation (S) is a part of the primary radiation (P) reflected by the sample (2); creation of an interferometer-based detection signal for a plurality of sample areas, each with at least one location point, using a detection ...

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    4. Acquistion and analysis techniques for improved outcomes in optical coherence tomography angiography

      Acquistion and analysis techniques for improved outcomes in optical coherence tomography angiography
      Abstract

      Methods for improved acquisition and processing of optical coherence tomography (OCT) angiography data are presented. One embodiment involves improving the acquisition of the data by evaluating the quality of different portions of the data to identify sections having non-uniform acquisition parameters or non-uniformities due to opacities in the eye such as floaters. The identified sections can then be brought to the attention of the user or automatically reacquired. In another embodiment, segmentation of layers in the retina includes both structural and flow information derived from motion contrast processing. In a further embodiment, the health of the eye is evaluating ...

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    5. Downhole sensing via swept source lasers

      Downhole sensing via swept source lasers

      Systems and methods for performing downhole analysis within a well bore employ a swept source laser that can be sent downhole to generate high resolution images of the well bore. Various embodiments can also determine other physical properties of a below ground structure. The swept source lasers can create images using low-coherence interferometry or optical coherence tomography. Systems and methods may also be used to determine fluid flow rates towards the sensor at discrete points, such as individual perforations, by measuring the Doppler effect on the light back-scattered from the fluid. Fluid flow information could also be extracted by measuring ...

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    6. Broadband wavelength-swept light source system and apparatus employing the same

      Broadband wavelength-swept light source system and apparatus employing the same

      A light source system includes: a plurality of gain mediums configured to output a corresponding plurality of lights having different center wavelengths from each other; a first light source part configured to connect the plurality of gain mediums to each other in parallel and emit the plurality of lights; a wavelength-swept filter unit configured to sweep wavelengths of the plurality of lights output by the plurality of gain mediums and compensate for spectroscopic optical paths of the plurality of lights; a second light source part configured to connect the first light source part to the wavelength-swept filter unit in series ...

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      Mentions: Samsung
    7. Multiple measurement channel detector circuit for interferometers

      Multiple measurement channel detector circuit for interferometers

      A detector circuit for a multi-channel interferometer, typically as may be used in an optical coherence tomography device, comprising: a plurality of measurement channels (43) each comprising a measurement detector (31); and a balance channel (44) comprising a balance detector (30), each of the measurement detectors (31) and the balance detector (30) having a light sensitive area and an electrical output configured to output a signal indicative of the intensity of light incident on the light sensitive area, in which each measurement channel (43) is provided with a feedback circuit (40) comprising: a variable gain circuit (35) having an input ...

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    8. Calibration and image processing devices, methods, and systems

      Calibration and image processing devices, methods, and systems

      In part, the invention relates to systems and methods of calibrating a plurality of frames generated with respect to a blood vessel as a result of a pullback of an intravascular imaging probe being pullback through the vessel. A calibration feature disposed in the frames that changes between a subset of the frames can be used to perform calibration. Calibration can be performed post-pullback. Various filters and image processing techniques can be used to identify one or more feature in the frames including, without limitation, a calibration feature, a guidewire, a side branch, a stent strut, a lumen of the ...

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    9. Microscopic surgery system and navigation method guided by optical coherence tomography (OCT) and automated OCT imaging field calibration

      Microscopic surgery system and navigation method guided by optical coherence tomography (OCT) and automated OCT imaging field calibration

      Provided are a microscopic surgery system and a navigation method guided by optical coherence tomography. The microscopic surgery system may include: an object lens; a surgical microscope unit configured to perform two-dimensional imaging on an area to operate on via the object lens; an optical coherence tomography unit configured to perform two-dimensional tomography imaging on the area via the object lens, with an imaging field calibrated according to that of the surgical microscope unit; a processor configured to obtain navigation information based on the two-dimensional imaging by the surgical microscope unit and the two-dimensional tomography imaging by the optical coherence ...

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    10. Tunable laser array system

      Tunable laser array system

      A system for swept source optical coherence tomography, the system including a light source emitting multiplexed wavelength-swept radiation over a total wavelength range, the light source including N wavelength-swept vertical cavity lasers (VCL) emitting N tunable VCL outputs having N wavelength trajectories, a combiner for combining the N tunable VCL optical outputs into a common optical path to create the multiplexed wavelength-swept radiation, a splitter for splitting the multiplexed wavelength-swept radiation to a sample and a reference path, an optical detector for detecting an interference signal created by an optical interference between a reflection from the sample and light traversing ...

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    11. System for performing dual path, two-dimensional optical coherence tomography (OCT)

      System for performing dual path, two-dimensional optical coherence tomography (OCT)

      A system (10) for measuring a physical characteristic of an object (11) using dual path, two-dimensional Optical Coherence Tomography (OCT) includes an extended broadband light source (13) producing an incident light beam (14) and an interferometer (15) having a beam splitter (16) that splits the incident beam into first and second component (17, 18) beams and directs the second component beam (18) on to a moveable mirror (19) for creating an optical path difference between the first component beam (17) and a reflection (20) of the second component beam. A focusing lens (21) having a focal plane (22) focuses the ...

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    12. Simultaneous refractive index and thickness measurements with a monochromatic low-coherence interferometer

      Simultaneous refractive index and thickness measurements with a monochromatic low-coherence interferometer

      A scanning monochromatic spatial low-coherent interferometer (S-LCI) can be used to simultaneously measure geometric thickness and refractive index. The probe beam of the scanning S-LCI can be an off-axis converging single wavelength laser beam, and the decomposed incident angles of the beam on the sample can be accurately defined in the Fourier domain. The angle dependent phase shift of a plane parallel plate or other sample can be obtained in a single system measurement. From the angle dependent phase shift, the geometric thickness and refractive index of the sample can be simultaneously obtained. Additionally or alternatively, the S-LCI system can ...

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    13. Optical coherence elastography to assess biomechanics and detect progression of ocular and other tissues degenerative diseases

      Optical coherence elastography to assess biomechanics and detect progression of ocular and other tissues degenerative diseases

      An excitation force (internal or external) and phase-sensitive optical coherence elastography (OCE) system, used in conjunction with a data analyzing algorithm, is capable of measuring and quantifying biomechanical parameters of tissues in situ and in vivo. The method was approbated and demonstrated on an example of the system that combines a pulsed ultrasound system capable of producing an acoustic radiation force on the crystalline lens surface and a phase-sensitive optical coherence tomography (OCT) system for measuring the lens displacement caused by the acoustic radiation force. The method allows noninvasive and nondestructive quantification of tissue mechanical properties. The noninvasive measurement method ...

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    14. Multiple window processing schemes for spectroscopic optical coherence tomography (OCT) and fourier domain low coherence interferometry

      Multiple window processing schemes for spectroscopic optical coherence tomography (OCT) and fourier domain low coherence interferometry

      Current apparatuses and methods for analysis of spectroscopic optical coherence tomography (SOCT) signals suffer from an inherent tradeoff between time (depth) and frequency (wavelength) resolution. In one non-limiting embodiment, multiple or dual window (DW) apparatuses and methods for reconstructing time-frequency distributions (TFDs) that applies two windows that independently determine the optical and temporal resolution is provided. For example, optical resolution is provided. For example, optical resolution may relate to scattering information about a sample, and temporal resolution may be related to absorption or depth related information. The effectiveness of the apparatuses and methods is demonstrated in simulations and in processing ...

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    15. Optical beam scanner

      Optical beam scanner

      A scanning device is presented having a substrate with a first surface and an opposite, parallel second surface. A region of the substrate includes the first surface and the opposite parallel second surface, and is defined via an etching process through a thickness of the substrate, where the region remains attached to the substrate via one or more hinges. A waveguide is patterned over the first surface of the region and guides a beam of radiation along a length of the waveguide. The scanning device includes a facet located on the first surface of the region. The facet is designed ...

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    16. Integrated optical system and components utilizing tunable optical sources and coherent detection and phased array for imaging, ranging, sensing, communications and other applications

      Integrated optical system and components utilizing tunable optical sources and coherent detection and phased array for imaging, ranging, sensing, communications and other applications

      An integrated optical system includes a photonic integrated circuit (PIC) having a frequency tunable optical source, a coherent optical receiver, and an optical phased array for coupling light to/from a sample. The integrated optical system is configured such that when the optical source is tuned in optical frequency the receiver produces electrical signals that are processed to produce optical profile information about the sample

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      Mentions: Eric A. Swanson
    17. Ophthalmic examination apparatus and ophthalmic examination system

      Ophthalmic examination apparatus and ophthalmic examination system

      According to one embodiment, an ophthalmic examination apparatus includes an examination unit and an analyzer. The examination unit is used to optically examine a subject's eye. The analyzer is configured to analyze examination data obtained by the examination unit, and thereby generate risk information indicating the risk of a specific disease.

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    18. Interferometric distance measuring method for measuring surfaces, and such a measuring arrangement

      Interferometric distance measuring method for measuring surfaces, and such a measuring arrangement

      A distance measuring method for measuring surfaces uses a laser source having a frequency that can be modulated to tune a wavelength of a laser beam in a wavelength range. The laser beam is generated with a coherence length to provide a measuring beam and is emitted at the surface, located within a specified distance range, as a measuring beam. The measuring beam is back-scattered by the surface and is received again and used to interferometrically measure the distance from a reference point to the surface. The specified distance range lies at least partly outside of the coherence length. One ...

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    19. Biological tissue analysis by inverse spectroscopic optical coherence tomography

      Biological tissue analysis by inverse spectroscopic optical coherence tomography

      A method and system to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT) is disclosed. Tissue is modeled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. By measuring optical quantities of tissue (including the scattering power of the OCT spectrum, the reflection albedo .alpha. defined as the ratio of scattering coefficient .mu..sub.s, and the backscattering coefficient .mu..sub.b), the RI correlation function can be inversely deduced and the full set of optical scattering properties can be obtained.

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    20. Location indicator for optical coherence tomography in ophthalmic visualization

      Location indicator for optical coherence tomography in ophthalmic visualization

      An ophthalmic visualization system can include a computing device in communication with an OCT system configured to scan a surgical field to generate an OCT image. The computing device can be configured to determine locations within the surgical field corresponding to locations within the OCT image. The ophthalmic visualization system can also include an indicator mechanism in communication with the computing device and a surgical microscope configured to image the surgical field. The indicator mechanism can be configured to cause a location indicator to be positioned within a field of view of the surgical microscope. The location indicator can graphically ...

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      Mentions: Lingfeng Yu
    1-24 of 2238 1 2 3 4 ... 92 93 94 »
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