1. Articles in category: Funding

    1-24 of 958 1 2 3 4 ... 38 39 40 »
    1. Duke University Receives NIH Grant for Retinal Light Scattering Measurements as a Clinical Biomarker of Alzheimer's Disease

      Duke University Receives NIH Grant for Retinal Light Scattering Measurements as a Clinical Biomarker of Alzheimer's Disease

      Duke University Received a 2022 NIH Grant for $493,158 for Retinal Light Scattering Measurements as a Clinical Biomarker of Alzheimer's Disease. The principal investigator is Adam Wax. Below is a summary of the proposed work. The overall objective of this proposal is to demonstrate the clinical feasibility of a novel method Although deposition of amyloid plaques in brain tissue is the clearest pathological indicator of AD, it can only be detected during autopsy or positron emission tomography (PET) imaging, which can be prohibitively expensive. As a result, the most widely used approach for diagnosing AD continues to be ...

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    2. Cleveland Clinic Receives NIH Grant for Broad Bandwidth Transducers for High Resolution Information Rich IVUS

      Cleveland Clinic Receives NIH Grant for Broad Bandwidth Transducers for High Resolution Information Rich IVUS

      Cleveland Clinic Received a 2022 NIH Grant for $390,345 for Broad Bandwidth Transducers for High Resolution Information Rich IVUS. The principal investigator is Aaron Fleischman. Below is a summary of the proposed work. Intra-coronary imaging is a powerful clinical tool for decision making, treatment planning, and assessment of stent deployment. It is also a powerful research tool for plaque progression/regression, drug treatments, and device interventions. There are clear advantages and disadvantages of common intravascular imaging methods. Intravascular ultrasound (IVUS) provides good resolution and allows one to measure lumen narrowing, wall thickening, atheroma burden, and to a lesser extent ...

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    3. Duke University Receives NIH Grant for Whole Eye Optical Coherence Tomography to Improve Eye Care

      Duke University Receives NIH Grant for Whole Eye Optical Coherence Tomography to Improve Eye Care

      Duke University Received a 2022 NIH Grant for $367,585 for Whole Eye Optical Coherence Tomography to Improve Eye Care. The principal investigator is Anthony Kuo. Below is a summary of the proposed work. This research proposal from a multi-disciplinary team including ophthalmologists and biomedical engineers seeks to improve the imaging and characterization of posterior eye deformities such as in progressive or pathologic myopic and high intracranial pressure. The three-dimensional changes seen in the posterior eye with these diseases have usually been characterized using neuro-imaging. To make this assessment more available in the clinical ophthalmic setting, we will further develop ...

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    4. Cornell University Receives NIH Grant for Overcoming the Multiple Scattering Limit in Optical Coherence Tomography

      Cornell University Receives NIH Grant for Overcoming the Multiple Scattering Limit in Optical Coherence Tomography

      Cornell University Received a 2022 NIH Grant for $378,003 for Overcoming the Multiple Scattering Limit in Optical Coherence Tomography. The principal investigator is Steven Adie. Below is a summary of the proposed work. Extending imaging depth is one of the grand challenges in optical microscopy, and many creative approaches are under development to mitigate the detrimental impact of the phenomenon of ‘optical scattering’ and enable deeper optical imaging in scattering media. Light propagating in dense tissue undergoes scattering events that scramble the phase of the propagating optical wavefront, and thus disrupts the constructive interference needed to focus/spatially localize ...

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    5. OncoRes Medical raises another $12.5M

      OncoRes Medical raises another $12.5M

      OncoRes Medical announced that it raised $12.5 million for its handheld imaging device for identifying cancer cells. Perth, Western Australia-based OncoRes designed its imaging system to facilitate real-time tumor assessment, helping surgeons more accurately identify and remove cancerous tissue, including for breast cancer . The company won FDA breakthrough device designation in October 2020 for the device aimed at enabling surgeons to remove all cancer on the first try, thus avoiding a second procedure. When the handheld probe is applied to a region of interest, it provides micro-scale maps of the stiffness of the tissue — a key differentiator from healthy ...

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      Mentions: FDA OncoRes Medical
    6. MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions

      MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions

      Massachusetts Eye and Ear Infirmary Received a 2022 NIH Grant for $117,133 for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions. The principal investigator is Sunil Puria. Below is a summary of the proposed work. Our knowledge of cochlear mechanics is currently undergoing a revolution. While the basilar membrane (BM) has long been considered the principal structure in cochlear motion, new techniques such as optical coherence tomography (OCT) have instead revealed not only that the reticular lamina (RL) moves in a different pattern from the BM, but that it ...

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    7. Theia Imaging LLC Receives Grant for A Widefield, Handheld OCT system for Patients who are Unable to Cooperate

      Theia Imaging LLC Receives Grant for A Widefield, Handheld OCT system for Patients who are Unable to Cooperate

      Theia Imaging LLC Received a 2022 NIH Grant for $259,613 for A Widefield, Handheld OCT system for Patients who are Unable to Cooperat . The principal investigator is Christian Viehland. Below is a summary of the proposed work. Optical coherence tomography (OCT) is the standard of care for the diagnosis and monitoring of adult retinal diseases. However, most clinical OCT devices are large tabletop systems that are not suitable for use with infants, young children, and patients that are unable to cooperate (I/YC/UC patients). As these patients cannot communicate about disturbances to their vision, diagnosis of disease in ...

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    8. University of Southern California Receives NIH Grant for Cochlear mechanics in the mouse

      University of Southern California Receives NIH Grant for Cochlear mechanics in the mouse

      University of Southern California Received a 2022 NIH Grant for $623,326 for Cochlear mechanics in the mouse. The principal investigator is John Oghalai. Below is a summary of the proposed work. Sound pressure produces force across the mammalian cochlear partition, ultimately creating a vibratory traveling wave that propagates longitudinally up the cochlear duct. The key feature distinguishing this process from the non-mammalian cochlea is amplification, whereby forces produced by thousands of outer hair cells (OHCs) sharpen and amplify the traveling wave. Our overarching objective is to understand how the complex biomechanics of the 3D multi-cellular and acellular arrangement that ...

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    9. Oregon Health & Science University Receives NIH Grant for Artificial intelligence assisted panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity

      Oregon Health & Science University Receives NIH Grant for Artificial intelligence assisted panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity

      Oregon Health & Science University Received a 2022 NIH Grant for $377,300 for Artificial intelligence assisted panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity. The principal investigator is Yifan Jian. Below is a summary of the proposed work. The long-term goal of this project is to determine whether optical coherence tomography (OCT) and OCT angiography (OCTA) might lead more accurate and objective diagnosis, earlier intervention, and improved outcomes in retinopathy of prematurity (ROP). International consensus and National Institute of Health (NIH) funded clinical trials over the last 30 years have defined the phenotypic classifications, natural history, prognosis, and management ...

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    10. Oregon Health & Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

      Oregon Health & Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

      Oregon Health & Science University Received a 2022 NIH Grant for $373,450 for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas. The principal investigator is Yan Li. Below is a summary of the proposed work. To see well, the cornea must maintain near perfect clarity and shape. Several disease processes can distort corneal shape and degrade vision. These include ectasia/keratoconus (stromal thinning and bulging), primary epithelial deformation (contact lens-related warpage, dry eye, epithelial basement membrane dystrophy), and stromal changes (scar, stromal dystrophy, surgery). Some of these conditions can appear similar on standard anterior topography and yet require ...

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    11. Ontario Government Makes Strategic Investments in Conavi Medical

      Ontario Government Makes Strategic Investments in Conavi Medical

      The Ontario government is supporting investments of more than $10 million by two Ontario companies with $5 million through the Ontario Together Fund. These projects will help to grow local manufacturing capacity, accelerate the commercialization of domestic life sciences innovations, and strengthen the province’s pandemic preparedness while creating 22 new, local jobs. “The Ontario Together Fund is helping Ontario businesses to fully develop their ideas and innovate in our diverse life sciences sector,” said Vic Fedeli, Minister of Economic Development, Job Creation and Trade. “Our government is proud to partner with companies like Conavi Medical and ventureLAB as they ...

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    12. Vanderbilt University at Davis Receives a 2022 NIH Grant for smartOCT: a low-cost technology to detect and monitor glaucoma in outpatient and primary care centers

      Vanderbilt University at Davis Receives a 2022 NIH Grant for smartOCT: a low-cost technology to detect and monitor glaucoma in outpatient and primary care centers

      Vanderbilt University at Davis Received a 2022 NIH Grant for $379,045 for smartOCT: a low-cost technology to detect and monitor glaucoma in outpatient and primary care centers. The principal investigator is Audrey Bowden. Below is a summary of the proposed work. Glaucoma is the leading cause of irreversible vision loss globally. Nearly 52.7 million people will be affected in 2020, and that number will grow to ~79.8 million by 2040. The prevalence varies by ethnicity, and the rates of undiagnosed primary open angle glaucoma are alarmingly high (50-85%) in white, black and Latino patients. The challenge in ...

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    13. UIUC Receives a 2022 NIH Grant f for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media

      UIUC Receives a 2022 NIH Grant f for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media

      University of Illinois at Urbana-Champaign Received a 2022 NIH Grant for $567,377 for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media. The principal investigator is Stephan Boppart. Below is a summary of the proposed work. Otitis media (middle ear infection) is a highly prevalent disease, especially in young children. It has been documented that more than 75% of children will have at least one episode of otitis media (OM) by age 3, and many children will have recurrent or chronic OM. In most cases, diagnosis of an ear infection is performed ...

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    14. Scinvivo Closes an Investment Round of 1 Million Euro from NextStage Early Stage Fund

      Scinvivo  Closes an Investment Round of 1 Million Euro from NextStage Early Stage Fund

      Scinvivo, a MedTech startup based in Eindhoven, has closed an investment round of 1 Million Euro from NextStage Early Stage Fund (NSESF), Innovatiefonds Noord-Holland and current shareholders. With this investment Scinvivo has secured the development of in human clinical trials and CE certification. Scinvivo is on a mission to make cancer diagnostics faster and more accurate, enabling reduction of unnecessary surgeries and improving the quality of patients' lives. Scinvivo develops an imaging platform based on a forward looking OCT catheter to visualise the human morphological tissue structure a few mm’s deep with a high resolution.This approach fills the ...

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      Mentions: Scinvivo
    15. Siloton Announces C.£470K Investment Round

      Siloton Announces  C.£470K Investment Round

      Siloton Limited , a revolutionary new deep-tech startup, has announced the first closing of its investment round, totalling c.£470k. The funds will be used to further develop Siloton’s diagnostic imaging technology. By harnessing the power of photonic integrated circuits (PICs), this is set to revolutionise the way in which patients with eye disease interact with ophthalmology services. In addition to attaining key technology milestones, Siloton will seek to form partnerships with key stakeholders and members of the global supply chain. The round was led by Quantum Exponential Group PLC and Evenlode Impact who invests to build a diversified start-up ...

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      Mentions: Siloton Limited
    16. Johns Hopkins University Receives NIH Grant for Imaging neurodegeneration in multiple sclerosis

      Johns Hopkins University Receives NIH Grant for Imaging neurodegeneration in multiple sclerosis

      Johns Hopkins University Received a 2022 NIH Grant for $536,829 for Imaging neurodegeneration in multiple sclerosis . The principal investigator is Peter Calabresi. Below is a summary of the proposed work. One of the significant challenges facing treatment of people with multiple sclerosis (MS) is determining their individual likelihood of progression, as this information would significantly influence the type of therapy selected. Thus, developing specific tools to monitor and predict progression is critical to better manage patient care and to understand mechanisms of disease. We have been developing a multi-faceted approach to more readily monitor (through imaging) and predict (through ...

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    17. University of California at Davis Receives NIH Grant for Investigating fundamental properties and clinical applications of the optoretinogram

      University of California at Davis Receives NIH Grant for Investigating fundamental properties and clinical applications of the optoretinogram

      University of California at Davis Received a 2022 NIH Grant for $372,763 for Investigating fundamental properties and clinical applications of the optoretinogram. The principal investigator is Ravi Jonnal. Below is a summary of the proposed work. This grant will investigate the optoretinogram (ORG)–an experimental, all optical assay of human photoreceptor function–and its potential to reveal dysfunction at the cellular level. The ORG is based on adaptive optics optical coherence tomography (AO­OCT), which is the only existing way to produce 3D images of the living human retina with cellular resolution. It leverage our novel observation that light ...

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    18. University of Illinois at Chicago Receives NIH Grant for Functional tomography of neurovascular coupling interactions in healthy and diseased retinas

      University of Illinois at Chicago Receives NIH Grant for Functional tomography of neurovascular coupling interactions in healthy and diseased retinas

      University of Illinois at Chicago Received a 2022 NIH Grant for $303,539 for Functional tomography of neurovascular coupling interactions in healthy and diseased retinas. The principal investigator is Xincheng Yao. Below is a summary of the proposed work. This project is to investigate spatiotemporal interactions between neural activities and hemodynamic changes in the retina, and to explore quantitative mapping of retinal neurovascular coupling defects caused by neurodegenerative diseases. Retinal neurodegenerative diseases, such as age-related macular degeneration (AMD), retinitis pigmentosa (RP), diabetic retinopathy (DR) and glaucoma, can produce severe vision losses if medical interventions cannot be provided promptly. As one ...

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    19. University of Southern California Receives NIH Grant for Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure Disease

      University of Southern California Receives NIH Grant for Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure Disease

      University of Southern California Received a 2022 NIH Grant for $228,758 for Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure Disease. The principal investigator is Benjamin Xu. Below is a summary of the proposed work. Primary angle closure glaucoma (PACG), the most severe form of primary angle closure disease (PACD), is a leading cause of permanent blindness worldwide. Gonioscopy, a qualitative and subjective angle assessment method, is the current clinical standard for diagnosing PACD despite its limited ability to quantify disease severity, especially in patients with early angle closure. Anterior segment ...

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    20. Morgridge Institute for Research Receives NIH Grant for Development and Validation of Photothermal Optical Coherence Tomography for Retinal Imaging

      Morgridge Institute for Research Receives NIH Grant for Development and Validation of Photothermal Optical Coherence Tomography for Retinal Imaging

      Morgridge Institute for Research Received a 2022 NIH Grant for $232,173 for Development and Validation of Photothermal Optical Coherence Tomography for Retinal Imaging. The principal investigator is Melissa Skala. Below is a summary of the proposed work. Melanin is naturally present in the eye within the choroid, iris, and retinal pigment epithelium (RPE), a single layer of epithelial cells located posterior to the photoreceptors in the retina. Changes in retinal pigmentation normally happen with aging and are present in many ocular diseases. For example, age-related macular degeneration (AMD) is the predominant cause of vision loss in adults over 65 ...

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    21. Johns Hopkins Receives NIH Grant for Artificial intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Keratoplasty (AUTO-DALK)

      Johns Hopkins Receives NIH Grant for Artificial intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Keratoplasty (AUTO-DALK)

      Johns Hopkins University Received a 2022 NIH Grant for $397,691 for Artificial intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Keratoplasty (AUTO-DALK). The principal investigator is Jin U. Kang. Below is a summary of the proposed work. Contemporary ocular surgeries are performed by skilled surgeons through operating microscopes, utilizing freehand techniques and manually operated precision micro-instruments, where the outcomes are often limited by the surgeon's skill levels and experiences. To overcome these human factors, we have assembled an interdisciplinary team including a clinician-scientist and eye surgeon, an optical device scientist and medical robotic engineers to translate existing and ...

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    22. University of Illinois at Chicago Receives NIH Grant for Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathy

      University of Illinois at Chicago Receives NIH Grant  for Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathy

      University of Illinois at Chicago Received a 2022 NIH Grant for $351,666 for Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathy. The principal investigator is Xincheng Yao. Below is a summary of the proposed work. This project aims to establish differential artery-vein analysis in optical coherence tomography angiography (OCTA), and to validate comprehensive OCTA features for automated classification of diabetic retinopathy (DR). Early detection, prompt intervention, and reliable assessment of treatment outcomes are essential to prevent irreversible visual loss from DR. It is known that DR can target arteries and veins differently. Therefore, differential artery-vein ...

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    23. Skala to develop new imaging approach for retinal diseases

      Skala to develop new imaging approach for retinal diseases

      Melissa Skala , a professor of biomedical engineering at the University of Wisconsin-Madison, has landed a grant from the National Eye Institute to develop a new imaging method for quantifying melanin levels in human eyes. The approach could allow for earlier disease detection and monitoring, as well as better treatment evaluation in retinal diseases, including age-related macular degeneration. Skala’s project is another collaboration with Joseph Carroll, an ophthalmology professor and director of the Advanced Ocular Imaging Program at the Medical College of Wisconsin in Milwaukee. Through the two-year, $480,135 grant, Skala will develop a technique called photothermal optical coherence ...

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