1. Articles in category: Funding

    1-24 of 624 1 2 3 4 ... 24 25 26 »
    1. MGH Receives NIH Grant for $1,512,015 for Center for Biomedical OCT Research and Translation.

      MGH Receives NIH Grant for $1,512,015 for Center for Biomedical OCT Research and Translation.

      Massachusetts General Hospital Receives a 2017 NIH Grant for $1,512,015 for Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2021. Below is a summary of the proposed work. Overall the Center for Biomedical OCT Research and Translation seeks to push the technological frontier of optical coherence tomography instrumentation and methods in response to challenges in biology and medicine. Fundamental to our approach, CBORT thrives on an intimate, push-pull relationship between physicists/engineers and biological, pre-clinical and clinical scientists. The most direct impact o the Resource ...

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    2. UIUC Receives a NIH Grant for Partnership for Primary Care Imaging of the Ear

      UIUC Receives a NIH Grant for Partnership for Primary Care Imaging of the Ear

      University of Illinois at Urbana-Champaign Receives a 2017 NIH Grant for $454,301 for Partnership for Primary Care Imaging of the Ear. The principal investigator is Stepen Boppart. The program began in 2011 and ends in 2019. Below is a summary of the proposed work. Biofilms in the human middle-ear are known to be directly associated with chronic otitis media (OM), and the bacteria that reside within these protective biofilms are likely responsible for contributing to the persistence and re-seeding of the infection despite repeated doses of antibiotics. While prior sampling of human middle-ear biofilms was performed invasively during a ...

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    3. University of Arizona Receives NIH Grant for Advanced Salpingoscope for Minimally-Invasive Imaging of the Fallopian Tubes

      University of Arizona Receives NIH Grant for Advanced Salpingoscope for Minimally-Invasive Imaging of the Fallopian Tubes

      University of Arizona Receives a 2017 NIH Grant for $334,425 for Advanced Salpingoscope for Minimally-Invasive Imaging of the Fallopian Tubes. The principal investigator is Jennifer Barton. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The fallopian tubes harbor serous tubal intraepithelial carcinoma (STIC), the putative precursor to high- grade serous ovarian carcinoma, the deadliest form of this disease with a 70% mortality rate. Early detection of STIC could save lives as well as prevent thousands of unnecessary prophylactic salpingo-oophorectomies. Unfortunately, early disease of the fallopian tubes is undetectable via conventional ...

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    4. Cornell University Receives a NIH Grant for Volumetric Traction Force Tomography of Collective Sell Migration Dynamics

      Cornell University Receives a NIH Grant for Volumetric Traction Force Tomography of Collective Sell Migration Dynamics

      Cornell University Receives a 2017 NIH Grant for $236,125 for Volumetric Traction Force Tomography of Collective Sell Migration Dynamics. The principal investigator is Steven Adie. The program began in 2016 and ends in 2018. Below is a summary of the proposed work. The understanding of cancer has evolved rapidly over the last decade, particularly with discoveries regarding the role of physical factors, such as extracellular matrix (ECM) stiffness and cellular forces, in carcinogenesis. This research has shown that altered ECM stiffness is not just a symptom of tumors, but is now known to trigger the actual onset of and ...

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    5. University of California at Berkeley Receives NIH Grant for Interferometric Optophysiology of the Human Retina

      University of California at Berkeley Receives NIH Grant for Interferometric Optophysiology of the Human Retina

      University of California at Berkeley Receives a 2017 NIH Grant for $618,742 for Interferometric Optophysiology of the Human Retina. The principal investigato is Austin Roorda. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. Our goal is to develop a new technology for non-invasive optical monitoring of activity of individual retinal neurons and their light-driven inputs at cellular resolution, in the living human retina. If successful, this technology will provide an entirely new and objective approach to understand and monitor treatment of retinal disease, thereby transforming scientific studies of the eye ...

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    6. Compact Imaging Teams with SRI International for Dynamic Biometrics Development under IARPA Odin Program

      Compact Imaging Teams with SRI International for  Dynamic Biometrics Development under IARPA Odin Program

      Compact Imaging, Inc. (CI) today announced that SRI International has selected CI’s non-invasive depth scanning sensor, MRO™, as a critical component in the development of “dynamic biometrics” for improved detection of attempts to evade or deceive biometric security systems, such as fingerprint scanners. The development is being performed under a multi-year contract awarded to SRI as part of IARPA’s (Intelligence Advanced Research Projects Activity, National Intelligence Directorate) Odin Program. The goal of the Odin Program is to develop advanced technologies to detect “presentation attacks,” as attempts to deceive biometric security systems are often called. Conventional biometrics, such as ...

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    7. Optical coherence tomography device and control program

      Optical coherence tomography device and control program

      An optical coherence tomography device includes an OCT optical system; a processor. The processor executes: an image generation processing of processing first OCT signals, and generating, based on the first OCT signals, a three-dimensional motion contrast image which is obtained by imaging a moving object in the scanning position; a Doppler shift detection processing of detecting Doppler shift in a scanning position specified on the three-dimensional motion contrast image, the plurality of second OCT signals being detected at timings different from the timings when the plurality of first OCT signals are detected; and a velocity obtaining processing of obtaining an ...

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      Mentions: Nidek
    8. Yale University Receives NIH Grant for Quantitative Optical Imaging of Cilia-Driven Fluid Flow

      Yale University Receives NIH Grant for Quantitative Optical Imaging of Cilia-Driven Fluid Flow

      Yale University Receives a 2017 NIH Grant for $416,250 for Quantitative Optical Imaging of Cilia-Driven Fluid Flow. The principal investigator is Mustafa Khokha. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Respiratory diseases are major causes of pediatric morbidity and mortality. These diseases are incompletely understood, which is a barrier to improving clinical care. Therefore, new mechanisms of disease need to be discovered. Optical imaging (e.g. optical coherence tomography [OCT]) will enable these discoveries since traditional imaging (e.g. x-ray, CT, MRI) cannot visualize structures smaller than ~1 mm ...

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    9. Columbia University Receives NIH Grant for Structural and Functional Progression of Glaucomatous Damage or the Macula

      Columbia University Receives NIH Grant for Structural and Functional Progression of Glaucomatous Damage or the Macula

      Columbia University Receives a 2017 NIH Grant for $400,000 for Structural and Functional Progression of Glaucomatous Damage or the Macula. The principal investigator is Carlos De Moraes. The program began in 2015 and ends in 2018. Below is a summary of the proposed work. There is compelling evidence that glaucomatous damage to the macula occurs even in early stages of the disease. The macula comprises about 30% of all retinal ganglion cells and its information corresponds to over 50% of the visual cortex. However, glaucomatous damage to the macula is often missed in clinical practice. Some of the reasons ...

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    10. Johns Hopkins Receives a NIH Grant for Eye Determinants of Cognition (EYEDOC) Study

      Johns Hopkins Receives a  NIH Grant for Eye Determinants of Cognition (EYEDOC) Study

      Johns Hopkins Receives a 2017 NIH Grant for $711,223 for Eye Determinants of Cognition (EYEDOC) Study. The principal investigator is Alison Abraham. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. Eye Determinants of Cognition (EyeDOC) Study Rationale: Dementia and mild cognitive impairment (MCI) pose enormous health and societal costs in our aging US population. While cerebral neural loss is known to contribute to Alzheimer's dementia, vascular diseases may contribute substantially to the total burden of dementia and its precursor, MCI. Small-vessel cerebrovascular changes, which are most strongly associated with ...

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    11. Beth Israel Deaconess Medical Center Receives NIH Grant for In Vivo Optical Detection of Dysplasia in Esophagus

      Beth Israel Deaconess Medical Center Receives  NIH Grant for In Vivo Optical Detection of Dysplasia in Esophagus

      Beth Israel Deaconess Medical Center Receives a 2017 NIH Grant for $598,587 for In Vivo Optical Detection of Dysplasia in Esophagus. The principal investigator is Lev Perelman. The program began in 2005 and ends in 2020. Below is a summary of the proposed work. Esophageal adenocarcinoma is the most common esophageal malignancy in Western world and the malignancy that is rising the fastest in the United States – approximately 7% per year over the past 30 years. It has very poor prognosis with less than 15% of patients alive 5 years after diagnosis. Worldwide, 482,300 new esophageal cancer cases ...

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    12. Breast cancer imaging invention to improve surgery accuracy gets funding for clinical trials

      Breast cancer imaging invention to improve surgery accuracy gets funding for clinical trials

      An Australian invention aimed at improving the accuracy of breast cancer surgery is a step closer to being launched on the global market after securing funding for medical trials. About a quarter of breast cancer patients currently require two rounds of surgery because surgeons, working mostly by touch, are unable to detect microscopic tumours during the first operation. A hand-held imaging probe developed by biomedical engineers at the University of Western Australia will be able to identify those tumours in real-time during the first surgery. "Surgeons are relying on pretty primitive tools at the moment," lead researcher Brendan Kennedy said ...

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    13. OncoRes Medical backed by MRCF to develop innovative imaging technology for breast cancer surgery

      OncoRes Medical backed by MRCF to develop innovative imaging technology for breast cancer surgery

      OncoRes Medical Pty Ltd, a new medical device company established to develop an imaging tool to improve the outcome of breast cancer surgery, will receive up to AU$6M of venture capital investment from the Medical Research Commercialisation Fund (MRCF). The funding will go towards developing a handheld imaging probe and console which will provide real-time intraoperative guidance to surgeons by assisting with the delineation of tumour from healthy tissue, at a microscopic level. Breast cancer has the second highest mortality rate of all cancers in women. In 2016 there were approximately 16,000 new cases of breast cancer diagnosed ...

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    14. Northwestern University Receives NIH Grant for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography

      Northwestern University Receives NIH Grant for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography

      Northwestern University Receives a 2017 NIH Grant for $48,576 for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography. The Principal Investigator is Brian Soetikno. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. The retina is one of the most metabolically active tissues in the human body, making it particularly susceptible to hypoxia. In diabetic retinopathy (DR), aberrant oxygen metabolism has been hypothesized to play a pivotal role its pathogenesis. An improved understanding of how imbalances in oxygen delivery and demand lead to the progression of DR ...

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    15. A group of 28 students affiliated with the University of Arizona has received the prestigious National Science Foundation Graduate Research Fellowship.

      A group of 28 students affiliated with the University of Arizona has received the prestigious National Science Foundation Graduate Research Fellowship.

      David Vega , a doctoral student finishing his first year in the optical sciences program. Vega's research is based on early detection of ovarian cancer using optical coherence tomography and multiphoton microscopy. The breakthrough technologies he is developing are transferable to numerous applications and offer broad impacts in several other fields, ranging from other medical diagnostics to astronomy

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    16. Piccolo project develops endoscope for colon cancer diagnosis

      Piccolo project develops endoscope for colon cancer diagnosis

      New instrument from Horizon 2020 project will use OCT and MPT for high-resolution imaging. Piccolo project: the European consortium A project funded under the EU Horizon 2020 program aims to develop a novel endoscope for the identification and diagnosis of colorectal cancer, the latest step in the use of optical technologies to tackle one of the world's predominant cancers. Running for three years until December 2019, and involving nine European industrial and research partners led by Spain's Tecnalia Research & Innovation research center, the Piccolo project envisages an advanced endoscope instrument able to deliver high-resolution structural and functional imaging ...

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    17. USC ReceivesNIH Grant for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans

      USC ReceivesNIH Grant for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans

      University of Southern California Receives a 2017 NIH Grant for $223,560 for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans. The principal investigator is Grace Richter. The program began in 2017 and ends in 2022. Below is a summary of the proposed work. This K23 application is submitted by Grace Richter, MD, MPH, an Assistant Professor of Ophthalmology in the Glaucoma Division at the USC Roski Eye Institute at Keck School of Medicine of University of Southern California. The primary objectives of this K23 career development proposal are: 1) to ...

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    18. University of Miami Receives NIH Grant for Reversible Dysfunction of Retinal Ganglion Cells in Glaucoma

      University of Miami Receives NIH Grant for Reversible Dysfunction of Retinal Ganglion Cells in Glaucoma

      The University of Miami Receives a 2017 NIH Grant for $310,837 for Reversible Dysfunction of Retinal Ganglion Cells in Glaucoma. The principal investigator is Vittorio Porciatti. The program began in 2003 and ends in 2018. Below is a summary of the proposed work. Glaucoma causes progressive damage and death of retinal ganglion cells (RGCs) resulting in blindness. The prevalence of the disease will rise to a projected 3 million Americans by 2020. Our long-term goal is to prevent RGC death in the early stages of glaucoma and preserve vision. The objective of this study is to identify dysfunctional RGCs ...

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    19. Stanford University Receives NIH Grant for Cochlear Mechanics in the Mouse

      Stanford University Receives NIH Grant for Cochlear Mechanics in the Mouse

      Stanford University Receives a 2017 NIH Grant for $307,982 for Cochlear Mechanics in the Mouse. The principal investigator is John Oghalai. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. Sound pressure produces force across the mammalian cochlear partition, ultimately creating a vibratory traveling wave that propagates longitudinally up the cochlear duct. The key feature distinguishing this process from the non-mammalian cochlea is amplification, whereby forces produced by thousands of outer hair cells (OHCs) sharpen and amplify the traveling wave. Our overarching objective is to understand how the complex biomechanics of ...

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    20. Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients

      Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients

      Massachusetts General Hospital Receives a 2017 NIH Grant for $865,789 for Intracoronary Imaging of Plaque Collagen in Patients. The principal investigator is Seemantini Nadkarni. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The goal of this proposal is to develop and validate an intracoronary imaging device for the assessment of plaque collagen content and architecture in patients. Acute myocardial infarction (AMI), caused by the rupture of unstable plaque, is the leading cause of death worldwide. Collagen and vascular smooth muscle cells (vSMCs) together impart mechanical stability to a plaque, and ...

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    21. Physical Sciences ReceivesNIH Grant for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes

      Physical Sciences ReceivesNIH Grant  for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes

      Physical Sciences Incorporated Receives a 2017 NIH Grant for $230,823 for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes. The principal investigator is Mircea Mujat. The program began in 2017 and ends in 2018. Below is a summary of the proposed work. There is currently a significant need for new non-invasive imaging techniques able to accurately quantify biomarkers for early detection, diagnosis, and quantification of complications in type 1 diabetes (T1D) such as diabetic retinopathy (DR). Physical Sciences Inc. (PSI) proposes to develop an imaging platform based on a new detection arrangement retrofitted to ...

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    22. University of Houston Receives NIH Grant f for Optical Coherence Elastography of the Cornea

      University of Houston Receives NIH Grant f for Optical Coherence Elastography of the Cornea

      University of Houston Receives a 2017 NIH Grant for $362,939 for Optical Coherence Elastography of the Cornea. The principal investigator is Kirill Larin. The program began in 2012 and ends in 2020. Below is a summary of the proposed work. Optical Coherence Elastography of the Cornea The fundamental physical properties of the outer tunic of the eye determine the structural characteristics of the ocular globe and may be altered in several devastating disease states including axial elongation in myopia, pathological deformation in keratoconus, and iatrogenic keratoectasia following corneal refractive surgery. These biomechanical tissue characteristics not only influence our clinical ...

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    23. The University of Wisconsin-Madison Receives Grant for Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases

      The University of Wisconsin-Madison Receives  Grant for  Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases

      The University of Wisconsin-Madison Receives a 2017 NIH Grant for $768,348 for Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases. The principal investigator is Ronald Klein. The program began in 1987 and ends in 2019. Below is a summary of the proposed work. This proposal builds on a longitudinal cohort study of persons participating in the Beaver Dam Eye Study (BDES), funded by National Eye Institute grant U10 EY006594. The study included persons aged 43-86 years living in the city and township of Beaver Dam, Wisconsin who were identified in a private census in 1987-88 and were examined ...

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    1-24 of 624 1 2 3 4 ... 24 25 26 »
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