1. Articles in category: Funding

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    1. Retinal imaging study to focus on early intervention

      Retinal imaging study to focus on early intervention

      UK firm Optos in potential £10M collaboration aiming for early detection of sight-threatening diseases. Optomap retinal imaging A new laser-based imaging technology for early detection of a range of serious eye diseases is set for a clinical study in the UK. Dunfermline-based Optos , which is listed on the London Stock Exchange, will work with Kent and Strathclyde Universities to develop a system that monitors the function of cells in patients’ eyes. The technology will then be used in clinical trials in Scotland, with the aim of detecting major sight-threatening diseases like glaucoma, age-related macular degeneration (AMD) and diabetic retinopathy in ...

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    2. Prof. Christine Hendon Wins $2.4 Million in Funding with NIH 2014 New Innovator Award | Electrical Engineering

      Prof. Christine Hendon Wins $2.4 Million in Funding with NIH 2014 New Innovator Award | Electrical Engineering

      Christine Hendon , assistant professor of electrical engineering, has won a $2.4 million five-year New Innovator Award from the National Institutes of Health (NIH), under its High Risk-High Reward program for scientists proposing highly innovative approaches to major contemporary challenges in biomedical research. $900,000 of the award will go to Columbia Engineering in indirect costs. She is one of 50 researchers to receive this prestigious award, established in 2007 for young investigators to conduct exceptionally innovative research. “I am very pleased and honored that my work has received such recognition from the NIH,” says Hendon, whose research is focused ...

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    3. OHSU Receives a NIH Grant for Functional Optical Coherence Tomography-Derived Biomarkers for Diabetic Retinopathy

      OHSU Receives a NIH Grant for Functional Optical Coherence Tomography-Derived Biomarkers for Diabetic Retinopathy

      Oregon Health & Science University Receives a 2014 NIH Grant for $1,1036,724 for Functional Optical Coherence Tomography-Derived Biomarkers for Diabetic Retinopathy. The principal investigator is Yali Jia. The program geban in 2014 and ends in 2017. Below is a summary of the proposed work. Diabetic retinopathy (DR), associated with long-term diabetes mellitus, is a leading cause of blindness in the US. Structural optical coherence tomography (OCT) has become the standard method for evaluating diabetic macular edema; however, fluorescein angiography (FA), which requires an invasive intravenous dye injection, is still needed to assess capillary dropout and confirm neovascularization. Recently, we ...

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    4. Praevium Research Receives NIH Grant for VCSEL Technology for Ultrahigh Speed OCT Retinal and Anterior Eye Imaging.

      Praevium Research Receives NIH Grant for VCSEL Technology for Ultrahigh Speed OCT Retinal and Anterior Eye Imaging.

      Praevium Research Receives a 2014 NIH Grant for $426,962 for VCSEL Technology for Ultrahigh Speed OCT Retinal and Anterior Eye Imaging. The principal investigator is Vijaysekhar Jayaraman. The program began in 2012 and ends in 2015. Below is a summary of the proposed work. The ultimate goal of this program is to enable a new generation of high performance, low cost ophthalmic Optical Coherence Tomography OCT technology based on new MEMS-tunable vertical cavity surface-emitting laser (MEMS-VCSEL) swept light sources. This will be accomplished by developing, validating, and commercializing VCSEL technology for swept source OCT (SS-OCT) at 850nm and 1050nm ...

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    5. UCLA Receives NIH Grant for An Intraocular Robotic Surgical System for Cataract Surgery Project.

      UCLA Receives NIH Grant for An Intraocular Robotic Surgical System for Cataract Surgery Project.

      University of California Los Angeles Receives a 2014 NIH Grant for $46,275 for An Intraocular Robotic Surgical System for Cataract Surgery Project. The principal investigator is Jean-Pierre Hubschman. The program began in 2014 and ends in 2016. Below is a summary of the propose work. Surgical outcomes have been dramatically improved in the last 2 decades through the integration of new technologies including among other innovative visualization systems and robotic assistance. We think that cataract surgery can also benefit from these advancements and we envision that cataract surgery will possibly be entirely performed in fifteen years from now by ...

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    6. Bioptigen Receives NIH Grant for Intrasurgical Optical Coherence Tomography

      Bioptigen Receives NIH Grant for Intrasurgical Optical Coherence Tomography

      Bioptigen Receives 2014 NIH Grant for $225,000 for Intrasurgical Optical Coherence Tomography. The principal investigator is Eric Buckland. THe program begain in 2014 and ends in 2015. Below is a summary of the proposed work. Each year, over 20 million ophthalmic surgeries are performed worldwide. Indications for ophthalmic surgery include potentially blinding diseases, such as cataracts, diabetic retinopathy, macular disease, and retinal detachment. Surgeons performing these delicate procedures are challenged by the translucent nature of tissues in the eye, making it nearly impossible to visualize microstructural changes during surgery. Optical coherence tomography (OCT) is a non-contact, optical imaging modality ...

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    7. Sinoora Incorporated Receives NIH Grant for On-Chip OCT for Ophthalmology Applications

      Sinoora Incorporated Receives NIH Grant for On-Chip OCT for Ophthalmology Applications

      Sinoora Incorporated Receives a 2014 NIH Grant for $149,999 for On-Chip OCT for Ophthalmology Applications. The principal investigator is Murtaza Askari. Below is a summary of the proposed work. Sinoora Inc. proposes to develop an on-chip spectral domain-optical coherence tomography (SD-OCT) system for ophthalmic applications. Phase I will concentrate on demonstrating the passive optical components of the OCT system on a single chip. The passive components include a spectrometer, coupler and an interferometer. These on- chip components will then be integrated with an off-chip broadband source and detector array to demonstrate OCT functionality. In Phase II, Sinoora will also ...

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    8. University of Maryland Receives NIH Grant for Monitoring Photo-Immunotherapy Using Multi-Channel Multi-Modal Imaging Needles

      University of Maryland Receives NIH Grant for Monitoring Photo-Immunotherapy Using Multi-Channel Multi-Modal Imaging Needles

      University of Maryland Receives a 2014 NIH Grant for $76,000 for Monitoring Photo-Immunotherapy Using Multi-Channel Multi-Modal Imaging Needles. The principal investigator is Yu Chen. The program began in 2014 and ends in 2016. Below is a summary of the proposed work. Photo-immunotherapy (PIT) is an emerging low-side-effect cancer therapy based on monoclonal antibody (mAb) conjugated with a near-infrared (NIR) phthalocyanine dye (IR700) that induces rapid cellular necrosis after exposure to near infrared light. Although single administration of the therapy (agent + light) was highly effective, recurrences were observed due to the inhomogeneous mAb-IR700 distribution in the tumor. Repeated therapy has ...

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    9. Bioptigen to Receive Grants Totaling $1.72 Million from the National Eye Institute for Development of Intraoperative SD-OCT

      Bioptigen to Receive Grants Totaling $1.72 Million  from the National Eye Institute for Development of Intraoperative SD-OCT

      Bioptigen announced today that the U.S. National Eye Institute, has allocated a total of $1.72 Million in grants to Bioptigen Inc. for development of microscope integrated intraoperative OCT technology. Presently, perioperative OCT imaging is performed using a hand-held probe, or by mounting such a probe to the surgical microscope. Under the new NEI grant, Bioptigen will advance development of a novel intraoperative OCT system integrated directly into the optical train of the surgical microscope. "The work advanced under these grants will bring surgeons one step closer to realizing the full value of intraoperative OCT," said Dr. Eric Buckland ...

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    10. New York University School of Medicine Receives 2014 NIH Grant to Study Hyperspectral Imaging of the Normal and Age-Related Macular Degeneration Fundus

      New York University School of Medicine Receives  2014 NIH Grant to Study Hyperspectral Imaging of the Normal and Age-Related Macular Degeneration Fundus

      A team with world-class expertise in ophthalmic disease, imaging, retinal pathology, and biomedical engineering will utilize hyperspectral imaging to provide, for the first time, in vivo molecular probing, validated with histopathologic correlation, of age-related macular degeneration (AMD). Their system, a specially modified fundus camera harnessed to cutting-edge biomedical image analysis techniques, will revolutionize the field by identifying the distribution and spectral signature of the various chromophores and fluorophores associated with AMD lesions. Drusen, the hallmark lesions of AMD, are biochemically heterogeneous and are key to understanding this disease. However, their composition cannot be determined in vivo with even the current ...

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    11. University of Texas at Arlington Receives NIH Grant to Study All Optical Control and Monitoring of Neural Activity.

      University of Texas at Arlington Receives NIH Grant to Study All Optical Control and Monitoring of Neural Activity.

      University of Texas at Arlington Received at 2014 NIH Grant for $206,065 to Study All Optical Control and Monitoring of Neural Activity. The principal investigator is Samarendra Mohanty. The program began in 2014 and ends in 2015. Below is a summary of the propose work. Success of optogenetic intervention of neural activity requires optimization of delivery of genes encoding light sensitive proteins (opsins) to specific cells, and to record the changes in cells and tissue during optogenetic stimulation. The most-commonly used method for delivering opsin(s) is use of viral vector, which is prone to cause unexpected inflammatory responses ...

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    12. Tornado Spectral Systems Announces Investment by Beauvest & Roadmap Captial

      Tornado Spectral Systems Announces Investment by Beauvest & Roadmap Captial

      Strategic Growth Round to Accelerate Global Expansion of Process Analyzers and Spectrometers-On-Chip Tornado Spectral Systems Inc., an emerging tech company developing radically superior tools for measuring the chemical composition and structure of materials in real-time for a variety of demanding industrial processes, announced additional funding led by venture capital firms BeauVest and Roadmap Capital. The new investments will be used to finance Tornado’s continued growth in North America and globally. With proprietary optical and nanophotonic technologies that overcome the limitations of conventional spectroscopy-based analyzers, Tornado Spectral Systems has developed a new class of instruments that can acquire chemical signatures ...

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    13. Oregon Health & Science University Receives NIH Grant for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma

      Oregon Health & Science University Receives NIH Grant  for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma

      Oregon Health & Science University Receives a 2014 NIH Grant for $734,129 for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma. The principal investigator is David Huang. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness. Early diagnosis and close monitoring of glaucoma are important because the onset is insidious and the damage is irreversible. Advanced imaging modalities such as optical coherence tomography (OCT) have been used in the past 2 decades to improve the objective evaluation of glaucoma. OCT has higher axial spatial resolution ...

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    14. Oregon Health & Science University Receives 2014 NIH Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography

      Oregon Health & Science University Receives 2014 NIH  Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography

      Oregon Health & Science University Receives a 2014 NIH Grant for $713,409 for Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography. The principal investigator is David Huang. The program began in 2007 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) is a cross-sectional and 3-dimensional (3-D) imaging technology with very fine spatial resolution (5 um). This project develops the methods and software needed for high-precision OCT measurements of the eye to guide implant, laser, and transplant surgeries in the front part of the eye. In the proposed continuation of ...

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    15. Stanford University Receives Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives 2014 NIH Grant for $392,576 for Molecular Imaging of Protein Glycosylation in Living Subjects. The principal investigator is Adam De La Zerda. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic in time ...

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    16. Bioptigen Receives NIH Grant for Measuring Choroidal Blood Flow Imaging with Spectral Domain OCT

      Bioptigen Receives NIH Grant  for Measuring Choroidal Blood Flow Imaging with Spectral Domain OCT

      Bioptigen Receives 2014 NIH Grant for $223,583 for Measuring Choroidal Blood Flow Imaging with Spectral Domain OCT. The principal investigator is Eric Buckland. The program began in 2014 and ends in 2015. Below is a summary of the proposed work. Ophthalmic vascular diseases impact millions of Americans. Age-related macular degeneration and diabetic retinopathy are the two major diseases with a well- known vascular factor. The role of the vascular system in glaucoma and retinopathy of prematurity is more insidious. The vascular theory of glaucoma suggests that the blood supply to the eye is a contributory factor in glaucoma. Advanced ...

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    17. Johns Hopkins University Receives NIH Grant for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives NIH Grant  for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives a 2014 NIH Grant for $681,519 for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo. The principal investigator is Robert Brown. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. This Biomedical Research Partnership (BRP) proposal involves a partnership among a biomedical engineering team, a pulmonary physiology team, and a clinical pulmonary medicine team. This research program will incorporate state of the art optical engineering, advanced in vivo physiologic evaluation, and direct application to human obstructive lung diseases (OLD). Optical coherence tomography (OCT) is ...

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    18. Children's Research Institute Receives NIH Grant to Study Visual Outcome Measures in Children with Optic Pathway Gliomas

      Children's Research Institute Receives NIH Grant  to Study Visual Outcome Measures in Children with Optic Pathway Gliomas

      Children's Research Institute Received a 2014 NIH Grant for $229,113 to Study Visual Outcome Measures in Children with Optic Pathway Gliomas. The principal investigator is Robert Avery. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. This Mentored Patient-Oriented Research Career Development Award will prepare a pediatric neuroophthalmologist for an academic career as an independent multidisciplinary clinical researcher with a focus on vision outcomes in children with brain tumors of the visual pathway called optic pathway gliomas (OPGs). The candidate's application provides training needed to establish a clinical research ...

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    19. University of Arizona Receives NIH Grant for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention

      University of Arizona Receives NIH Grant for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention

      University of Arizona Receives a 2014 NIH Grant for $294,662 for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention. The principal investigator is Steven Stratton The program began in 2014 and ends in 2015 Below is a summary of the proposed work. Project 3 will test and clinically validate mechanisms and pharmacologic strategies explored in Projects 1-2, which target Akt-mTOR, AMPK-mTOR, and Fyn/RSK pathways. Advanced clinical/translational study of skin cancer carcinogenesis, biology, and pathophysiology will help reduce morbidity/ mortality, provide insight into keratinocyte signaling, and provide an easily-accessed human model of full-spectrum carcinogenesis for other ...

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    20. Columbia University Receives NIH Grant for Measures Of Human Receptor and Post Receptor Activity

      Columbia University Receives NIH Grant for Measures Of Human Receptor and Post Receptor Activity

      Columbia University Receives 2014 NIH Grant for $532,143 for Measures Of Human Receptor and Post Receptor Activity. The principal investigator is Donald Hood. The program began in 1991 and ends in 2016. Below is a summary of the proposed work. Our long-term objective has been to develop a set of noninvasive techniques for studying the human retina. By applying novel techniques and current theories of phototransduction to the full-field electroretinogram (ERG), we have successfully developed widely-used noninvasive techniques for studying the global activity of the rod and cone receptors, as well as the rod bipolar cells. These indices of ...

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    21. University of Washington Received a 2014 NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas

      University of Washington Received a 2014 NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas

      University of Washington Received a 2014 NIH Grant For $232,550 for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas. The principal investigator is Eric Seibel. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. There are over three million needle biopsies performed every year in the USA, typically for the diagnosis of breast, prostate, thyroid, lung, liver, and pancreatic cancers. Because needle biopsies are less invasive than surgical biopsies, they are much more cost-effective. However, a major limitation for all needle biopsies are that the pathologist or cytologist ...

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    22. UC Irvine Receives NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      UC Irvine Receives NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Received a 2014 NIH Grant for $598,705 for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging. The principal investigator is Zhongping Chen. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography (OCT), ultrasound (US), and phase-resolved acoustic radiation force optical coherence elastography (ARF-OCE). The multimodal intravascular imaging system is unique in that it combines the advantages of the high spatial resolution ...

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    23. Johns Hopkins University Receives NIH Grant to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer

      Johns Hopkins University Receives  NIH Grant to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer

      Johns Hopkins University Receives a 2014 NIH Grant for $47,676 to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer. The principal investigator is Carmen Kut. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. In brain cancers such as gliomas, aggressive removal of the solid tumor through surgery is associated with improved overall survival. In fact, i has been shown that at least 78% of the tumor has to be removed to make a meaningful difference in the patient's survival. Current techniques for tumor removal ...

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    24. Stanford University Receives a NIH grant for Enhanced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a NIH grant  for Enhanced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a 2014 NIH grant for $460,742 for Enhanced Clinical Diagnosis of Early Osteoarthritis. The principal investigator was Constance Chu. The program began in 2005 and ends in 2016. Below is a summary of the proposed work. Osteoarthritis is a leading cause of disability, and a major public health issue. Progressive loss of articular cartilage due to injury and degeneration are important etiological factors in the development of osteoarthritis. While laboratory studies show a potential to reverse pathological changes in articular cartilage prior to breakdown of the articular surface, a major barrier to clinical translation of these ...

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