1. Articles in category: Funding

    1-24 of 471 1 2 3 4 ... 18 19 20 »
    1. Wasatch Photonics Receives a NIH Grant for a Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives a NIH Grant for a Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives a NIH Grant for $27,960 for a Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications. The principal investigator is Roman Kuranov. The program began in 2015 and ends in 2015. Below is a summary of the proposed work. During this SBIR Phase I project we propose to build and test in phantoms a prototype of an innovative cost-effective Optical Coherence Tomography (OCT) system with a 10X increase in acquisition rate compared to commercially available systems. Further development may add an additional 10X increased acquisition rate for a total of 100X. Current market demand for Mega ...

      Read Full Article
    2. MGH Receives NIH Grant for Developing Algorithms for MR and OCT-Based Architectonic and Laminar Segmentatio

      MGH Receives NIH Grant for Developing Algorithms for MR and OCT-Based Architectonic and Laminar Segmentatio

      Massachusetts General Hospital Receives a 2015 NIH Grant for $587,704 for developing Algorithms for MR and OCT-Based Architectonic and Laminar Segmentation. The principal investigator is Bruce Fischl. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. The human brain is made up of an array of functionally and structurally defined regions. Localizing these regions is critical for early diagnosis of an array of diseases such as Alzheimer's disease (AD), as well as for neuroscientific research aimed at understanding the brain's functional and structural properties and clinical intervention in drug-resistant ...

      Read Full Article
    3. OCT Medical Imaging Inc. Receives fast-track SBIR funding for “Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system

      OCT Medical Imaging Inc. Receives fast-track SBIR funding for “Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system

      Dr. Ram Ramalingam CEO of OCT Medical Imaging Inc., (OCTMI), a privately held medical device company announced that it has received a fast-tract Small Business Innovation Research (SBIR) grant from SBIR funding as National Heart Lung Blood institute (NHLBI) for “Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system”. This fast-track SBIR grant worth 2.9 million dollar with potential support for two and half-year will be led by Dr. Ram Ramalingam, Co-founder of OCTMI and will involve clinicians from Columbia University Medical School (CUMS) and University of California Irvine Medical School (UCIMS), Orange, California. This milestone based ...

      Read Full Article
    4. Stanford University Receives NIH Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives NIH Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives a 2015 NIH Grant for $392,576 for Molecular Imaging of Protein Glycosylation in Living Subjects. The principal investigator is Adam De La Zerda. The program began in 2012 and ends in 2017 The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic in time, space and environment. Hence, in order to ...

      Read Full Article
    5. Real-Time Automatic Segmentation of Optical Coherence Tomography Volume Data of the Macular Region

      Real-Time Automatic Segmentation of Optical Coherence Tomography Volume Data of the Macular Region

      Optical coherence tomography (OCT) is a high speed, high resolution and non-invasive imaging modality that enables the capturing of the 3D structure of the retina. The fast and automatic analysis of 3D volume OCT data is crucial taking into account the increased amount of patient-specific 3D imaging data. In this work, we have developed an automatic algorithm, OCTRIMA 3D (OCT Retinal IMage Analysis 3D), that could segment OCT volume data in the macular region fast and accurately. The proposed method is implemented using the shortest-path based graph search, which detects the retinal boundaries by searching the shortest-path between two end ...

      Read Full Article
    6. Oregon Health and Science University Receives NIH Grant for Studying In Vivo Organ of Corti Mechanoelectric Physiology

      Oregon Health and Science University Receives  NIH Grant for Studying In Vivo Organ of Corti Mechanoelectric Physiology

      Oregon Health and Science University Receives a 2015 NIH Grant for $370,365 for Studying In Vivo Organ of Corti Mechanoelectric Physiology. The principal investigator is Alfred Nuttall. THe program began in 1979 and ends in 2016. Below is a summary of the proposed work. A goal of the cochlear physiology laboratory is to understand how the components of the organ of Corti enhance the sound induced vibration of the basilar membrane, a process known as cochlear amplification (CA). Two questions of broad interest are to be studied; how do the outer hair cells transmit force to activate the CA ...

      Read Full Article
    7. Johns Hopkins University Receives NIH Grant for a OCT-Guided Free-Hand Semi-Automated Microsurgical Tool for Enhanced Retinal Surgery

      Johns Hopkins University Receives NIH Grant for a OCT-Guided Free-Hand Semi-Automated Microsurgical Tool for Enhanced Retinal Surgery

      Johns Hopkins University Receives a 2015 NIH Grant for $445,134 for a OCT-Guided Free-Hand Semi-Automated Microsurgical Tool for Enhanced Retinal Surgery. The principal investigator is Jin U. Kang. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Contemporary retinal microsurgery is performed by skilled surgeons through operating microscopes, utilizing free hand techniques and manually operated precision micro-instruments. We have assembled an interdisciplinary team including a clinician scientist and vitreoretinal surgeon, an optical device scientist and a systems integrator to translate existing and developing technology in our laboratories into practical application. To ...

      Read Full Article
    8. Columbia University Receives NIH Grant for Measures of Human Receptor and Post Receptor Activity

      Columbia University Receives NIH Grant  for Measures of Human Receptor and Post Receptor Activity

      Columbia University Receives a 2015 NIH Grant for $581,231 for Measures of Human Receptor and Post Receptor Activity. The principal investigator is Donald Hood. The program began in 1991 and ends in 2016. Below is a summary of the proposed work. Our long-term objective has been to develop a set of noninvasive techniques for studying the human retina. By applying novel techniques and current theories of phototransduction to the full-field electroretinogram (ERG), we have successfully developed widely-used noninvasive techniques for studying the global activity of the rod and cone receptors, as well as the rod bipolar cells. These indices ...

      Read Full Article
    9. Cleveland Clinic Receives NIH Grant to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives NIH Grant to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives a 2015 NIH Grant for $203,124 to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery. The principal investigatgor is Justis Ehlers. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Optical coherence tomography (OCT) has revolutionized the management of ophthalmic diseases with the precise anatomic information it provides with non-invasive imaging. The high-resolution cross-sectional tissue details make OCT a natural complement to ophthalmic surgery. Intraoperative OCT (iOCT) has the potential to provide real-time feedback to surgeons thus improving surgical care and outcomes. This research activity will focus on ...

      Read Full Article
    10. Atherectomy Catheters And Occlusion Crossing Devices

      Atherectomy Catheters And Occlusion Crossing Devices

      Atherectomy catheters and methods of using them are described herein. In particular, described herein are optical coherence tomography (OCT) catheters that may include a distal tip that can be deflected away from the long axis of the device at a hinge point that is offset (e.g., located on a side of the elongate body near the distal end of the elongate body) and a rotatable cutter near an imaging assembly that can be driven against the wall with a high mechanical advantage.

      Read Full Article
    11. University of Alabama at Birmingham Receives NIH Grant to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT.

      University of Alabama at Birmingham Receives NIH Grant to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT.

      The University of Alabama at Birmingham Receives a 2015 NIH Grant for $498,330 to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT. The principal investigator is Steven Mark Rowe. The program began in 2012 and elndsi nin 2016. Below is a summary of the proposed work. Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), an anion transporter of chloride and bicarbonate. Defective or deficient CFTR leads to severe mucoobstructive lung disease and severe morbidity and early mortality due to lung infections. Even though substantial advances in ...

      Read Full Article
    12. FedDev Ontario Supports Commercialization of Perimeter Medical Imaging’s OTIS™ Surgical Tissue Imaging System

      FedDev Ontario Supports Commercialization of Perimeter Medical Imaging’s OTIS™ Surgical Tissue Imaging System

      Perimeter Medical Imaging, Inc., a developer of real time imaging systems for in-surgery tumour margin assessment, today announced it is receiving up to $980,000 from the Government of Canada through the Federal Economic Development Agency for Southern Ontario (FedDev Ontario). The announcement was made at Perimeter’s new location in Toronto by John Carmichael, Member of Parliament for Don Valley West, on behalf of the Honourable Gary Goodyear, Minister of State for the Federal Economic Development Agency for Southern Ontario (FedDev Ontario). This investment will support the next phase of product and clinical development as well as accelerate regulatory ...

      Read Full Article
    13. Case Western Reserve University Receives NIH Grant for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging

      Case Western Reserve University Receives NIH Grant for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging

      Case Western Reserve University Receives a 2015 NIH grant for $198,125 for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging. The principal investigator is Andrew Rollins. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. The long-term goal of this research program is to develop catheter-based optical coherence tomography (OCT) imaging tools that will improve the care of patients suffering from cardiac arrhythmias. This project aims to improve radiofrequency ablation (RFA) therapy, which is the standard of care for many arrhythmias, by providing microscopic image guidance at the tip of the ...

      Read Full Article
    14. Johns Hopkins University Receives NIH Grant for Studying OCT to Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer.

      Johns Hopkins University Receives NIH Grant for Studying OCT to Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer.

      Johns Hopkins University Receives a 2015 NIH Grant for $48,120 for OCT to Distinguish B/T Tumor &Non-Tumor Tissue in Infiltrating Brain Cancer. The principal investigator is Carmen Kut. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. In brain cancers such as gliomas, aggressive removal of the solid tumor through surgery is associated with improved overall survival. In fact, i has been shown that at least 78% of the tumor has to be removed to make a meaningful difference in the patient's survival. Current techniques for tumor removal are ...

      Read Full Article
    15. Assessment of Cardiac Allograft Vasculopathy by Optical Coherence Tomography

      Assessment of Cardiac Allograft Vasculopathy by Optical Coherence Tomography

      Cardiac allograft vasculopathy (CAV) is characterized by marked intimal proliferation and concentric vascular thickening and fibrosis. CAV remains the leading cause of late morbidity and mortality in heart transplant recipients. Optical coherence tomography (OCT) is a new generation catheter-based modality that acquires images at a spatial resolution of 10-20 μm which is 10-fold greater than that of intravascular ultrasound (IVUS). OCT is currently the most sensitive imaging technique for early CAV detection. Recent studies proved that circulating human leukocyte antigen (HLA) directed donor-specific antibodies correlate with increased mortality and CAV. Contradiction of scientific results has been reported regarding increased resting ...

      Read Full Article
    16. Massachusetts General Hospital Receives NIH grant for the center for Biomedical OCT Research and Translation.

      Massachusetts General Hospital Receives  NIH grant for the center for Biomedical OCT Research and Translation.

      Massachusetts General Hospital Receives a 2015 NIH grant for $1,086,563 for the Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) has evolved into a powerful microscopy technique for a broad range of applications in biology and clinical medicine. It can safely be used to image biological tissue with high resolution and can easily integrate flexible, narrow diameter optical fiber probes for imaging internal organs. Recent advances have increased OCT imaging speeds by ...

      Read Full Article
    17. Stanford University Receives NIH Grant to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives  NIH Grant  to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a 2015 NIH Grant for $461,667 to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis. The principal investigator is Constance Chu. The program began in 2005 and ends in 2016. Below is a summary of the proposed work. Osteoarthritis is a leading cause of disability, and a major public health issue. Progressive loss of articular cartilage due to injury and degeneration are important etiological factors in the development of osteoarthritis. While laboratory studies show a potential to reverse pathological changes in articular cartilage prior to breakdown of the articular surface, a major barrier to clinical translation of ...

      Read Full Article
    18. UIUC Receives a NIH Grant for a Partnership for Primary Care Imaging

      UIUC Receives a NIH Grant for a Partnership for Primary Care Imaging

      University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $925,920 for a Partnership for Primary Care Imaging. The principal investigaror is Stephen Boppart. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Primary Care Medicine, including Family Practice and Pediatrics, has traditionally relied on physical exam skills and simplistic instruments for critical diagnostic decision making, monitoring, and referral to medical specialists. The otoscope and ophthalmoscope are two historical and ubiquitous instruments that largely only illuminate and magnify tissue surfaces in the ear and eye, respectively. This Partnership will develop a ...

      Read Full Article
    19. University of California Riverside Receives NIH Grant to Study Optical Detection of the Pre-Seizure State.

      University of California Riverside Receives NIH Grant to Study Optical Detection of the Pre-Seizure State.

      University of California Riverside received a 2015 NIH Grant for $441,942 to Study Optical Detection of the Pre-Seizure State. The principal investigator is Kevin Binder. The program began in 2013 and ends in 2016. Below is a summary of the proposed work. Reliable means of detecting changes which occur during the "pre-seizure state" could serve as a method of seizure prediction, a benchmark in epilepsy research (NIH Curing Epilepsy Conferences, 2000 and 2007). Our preliminary data indicate pre-seizure constriction in brain extracellular space (ECS) accompanied by reduction in near-infrared (NIR) optical scattering prior to detection of seizure by electroencephalography ...

      Read Full Article
      Mentions: UC Riverside
    20. UIUC Receives NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      UIUC Receives NIH Grant  for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      The University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $490,333 for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins. The principal investigator is Stephen Boppart. The program begain in 2012 and ends in 2017. Below is a summary of the proosed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving surgeries or lumpectomies are routinely performed. Currently, the surgeon is unable to visualize the microscopic structure at the margin, and conventionally relies on post-operative histological assessment of surgical margins to ...

      Read Full Article
    21. On the road to ubiquity

      On the road to ubiquity

      When the National Science Foundation (NSF) was founded in 1950, the laser didn't exist. Some 65 years later, the technology is ubiquitous. As a tool, the laser has stretched the imaginations of countless scientists and engineers, making possible everything from stunning images of celestial bodies to high-speed communications. Once described as a "solution looking for a problem," the laser powered and pulsed its way into nearly every aspect of modern life. For its part, NSF funding enabled research that has translated into meaningful applications in manufacturing, communications, life sciences, defense and medicine. NSF also has played a critical role ...

      Read Full Article
    22. MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      Massachusetts General Hospital Receives a 2015 NIH Grant for $472,417 To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. Barrett's esophagus (BE) is a condition where normal esophageal squamous mucosa changes to metaplastic columnar mucosa in response to chronic acid reflux. BE can progress to esophageal adenocarcinoma (EAC), a prevalent (~12,000 cases per year) and deadly cancer (~15% 5-year mortality rate). Current BE management strategies of anti-reflux therapy, endoscopic screening, and regular endoscopic biopsy surveillance and ablation therapy ...

      Read Full Article
    23. MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      Massachusetts General Hospital Receives a 2015 NIH Grant for $733,578 to Study Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function. The principal investigator is David Sosnovik. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. Pressure overload of the left and right ventricles initially leads to adaptive hypertrophy. This, however, is frequently followed by maladaptive hypertrophy, heart failure and death. We hypothesize here that changes in 3D myocardial fiber architecture play a significant role in the deleterious transition from adaptive to maladaptive hypertrophy and heart failure. We further hypothesize ...

      Read Full Article
    24. Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives a 2015 NIH Grant for $359,023 for Integrated Imaging of the Form and Function of the Beating Embryonic Heart. The principal investigator is Andrew Rollins. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Congenital heart defects (CHDs) afflict 36,000 babies born in the US each year and survivors often require several surgical interventions in their shortened lifetime. Despite continuous efforts, the mechanisms leading to CHDs remain largely unclear. In part, this is because most developmental cardiology studies fail to address the influential role of altered ...

      Read Full Article
    1-24 of 471 1 2 3 4 ... 18 19 20 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (1 articles) Massachusetts General Hospital
    2. (1 articles) Stanford University
    3. (1 articles) Johns Hopkins University
    4. (1 articles) Harvard University
    5. (1 articles) Oregon Health & Science University
    6. (1 articles) Columbia University
    7. (1 articles) University of Miami
    8. (1 articles) Cleveland Clinic
  4. People in the News

    1. (1 articles) Ram Ramalingam
    2. (1 articles) Alfred L. Nuttall
    3. (1 articles) Donald C. Hood
    4. (1 articles) Roman V. Kuranov
    5. (1 articles) Jin U. Kang
    6. (1 articles) Delia Cabrera DeBuc
    7. (1 articles) Justis P. Ehlers
  5. OCT Companies in the News

    1. (1 articles) Wasatch Photonics
    2. (1 articles) Heidelberg Engineering
    3. (1 articles) OCT Medical Imaging Inc
    4. (1 articles) Bioptigen
  6. OCT Products in the News

    1. (1 articles) Heidelberg Spectralis