1. Articles in category: Funding

    1-24 of 566 1 2 3 4 ... 22 23 24 »
    1. University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease

      University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease

      University of Alabam at Birmingham Receives a 2017 NIH Grant for $330,750 for In Vivo Ultrastruture of Chorioretinal Disease. The principal investigator is Yuhua Zhang. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. Age-related macular degeneration (AMD) is a leading cause of vision loss in more than 10 million older Americans. For decades, AMD has been characterized by accumulation of extracellular lesions called drusen on the inner surface of Bruch's membrane (BrM), posterior to the retinal pigment epithelium (RPE), in a compartment called the sub-RPE space. Drusen are now ...

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    2. Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Isreal Deaconess Medical Center Receives a 2017 NIH Grant for $164,376 for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology. The principal investigator is Eric Osborn. The program began in 2017 and ends in 2020. Below is a summary of the propose work. Dr. Eric Osborn is an early career faculty member at Beth Israel Deaconess Medical Center (BIDMC) and Massachusetts General Hospital (MGH), and an Instructor in Medicine at Harvard Medical School, Boston, Massachusetts. He is a graduate of the MD-PhD program at Harvard Medical School and Massachusetts Institute of Technology, and has completed clinical training in medicine ...

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    3. The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives a 2017 NIH Grant for $311,241 for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development. The principal investigator is Kirll Larin. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The overall objective of this study is to develop an optical coherence tomography (OCT) based high- resolution mouse embryonic brain imaging and analysis approach, and to use this method in correlation with molecular analysis to understand the interplay between ethanol (EtOH) and nicotine (NIC) effects on embryonic brain development. Maternal exposures ...

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    4. UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      The University of California at Davis Receives a 2017 NIH Grant for $97,834 for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT. The principal investigator is Ravi Jonnal. The program began in 2016 and ends in 2017. Below is a summary of the proposed work. The research proposed for this award will examine functional and structural properties of single cells in the human retina. The three Aims will link the candidate's scientific background and career plans to study the human retina using a combination of adaptive optics (AO) and optical coherence tomography (OCT) which provide high lateral ...

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    5. University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography.

      University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography.

      University of Miami Receives a 2017 NIH Grant for $227,722 for Endothelium/Descemet's Membrane Complex Optical Tomography. The principal investigator is Mohamed Shousha. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. More than 50% of corneal transplants, the most common form of solid organ transplantation, are performed to restore vision lost secondary to corneal endothelial failure. More than 25% of those transplants will eventually fail and endothelial cell rejection leading to failure is the single most important cause. The key to protec the endothelium is the early and accurate ...

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    6. Duke University Receives NIH Grant for Advanced A/LCI Systems for Improved Clinical Utility.

      Duke University Receives NIH Grant  for Advanced A/LCI Systems for Improved Clinical Utility.

      Duke University Receives a 2017 NIH Grant for $501,101 for Advanced A/LCI Systems for IMproved linical Utility. The principal investigator is Adam Wax. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. There is a critical unmet need for in vivo detection of dysplasia in patients with Barrett's esophagus (BE), a neoplastic tissue state resulting from chronic acid reflux. BE is associated with an increased risk of esophageal cancer, a disease with a high morbidity rate. Patients with BE undergo periodic endoscopic surveillance with systematic biopsy to search for ...

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    7. UIUC Receives a NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins

      UIUC Receives a NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins

      University of Illinois at Urbana-Champaign Receives a 2017 NIH Grant for $548,714 for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins. The principal investigator is Stephan Boppart. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. Breast cancer is a global healthcare burden, not only for the patients diagnosed with this disease, but also their families and friends. The surgical treatment of breast cancer, while successful, has significant limitations that increase patient anxiety, increase costs, and can increase the risk for local recurrence and lifelong post-operative complications. A primary limitation stems ...

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    8. 'Galahad' project to develop OCT for glaucoma diagnosis

      'Galahad' project to develop OCT for glaucoma diagnosis

      Multiple UK and Danish partners involved in €4M effort to develop high-res system based around supercontinuum source . Glaucoma: high-res imaging needed for diagnosis Gooch & Housego and NKT Photonics are among eight partners from the UK and Denmark who have just started work on a new €4 million European project to develop a high-resolution optical coherence tomography (OCT) system for glaucoma diagnosis. The “GALAHAD” (short for Glaucoma - Advanced, Label-free High Resolution Automated OCT Diagnosis) effort, funded through the European Commission’s Horizon 2020 innovation platform, officially kicked off this month and runs for three years. High-res requirements Current OCT systems offer ...

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    9. Wavelength tunable light source

      Wavelength tunable light source

      To provide a wavelength tunable light source which can both ensure operation speed and reduce a drive voltage. A wavelength tunable light source according to the present invention includes a pair of reflectors at least one of which is a movable reflector, an active layer provided between the pair of reflectors, and a beam on part of which the movable reflector is formed and which is supported by a support member. The beam includes a blade part projecting between the support member and the movable reflector in a direction intersecting a stretching direction of the beam, and a center of ...

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    10. Google researchers use deep learning to detect diabetic retinopathy with upwards of 90 percent accuracy

      Google researchers use deep learning to detect diabetic retinopathy with upwards of 90 percent accuracy

      A team of Google researchers has published a paper in the Journal of the American Medical Association showing that Google's deep learning algorithm, trained on a large data set of fundus images, can detect diabetic retinopathy with better than 90 percent accuracy. "These results demonstrate that deep neural networks can be trained, using large data sets and without having to specify lesion-based features, to identify diabetic retinopathy or diabetic macular edema in retinal fundus images with high sensitivity and high specificity," researchers write in the paper . "This automated system for the detection of diabetic retinopathy offers several advantages, including ...

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    11. #1 – OCT as a Diagnostic Tool

      #1 – OCT as a Diagnostic Tool

      In 1991, David Huang, MD, PhD, of the Massachusetts Institute of Technology described the first use of optical coherence tomography (OCT) for noninvasive cross-sectional imaging in biological systems. When the first commercial time-domain OCT (TD-OCT) debuted 5 years later, it was able to acquire data at a rate of only 100 axial scans per second. Six years later, this speed had quadrupled to 400 axial scans per second. As improvements in speed and quality persisted, OCT became the gold standard for diagnosis of glaucoma and many retinal diseases such as age-related macular degeneration and diabetic eye disease. OCT is based ...

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    12. New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives a 2016 NIH Grant for $714,891 for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. The program began in 2016 and ends in 2019. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness and visual morbidity. Because the disease causes irreversible damage to neural tissue it is of upmost importance to identify glaucoma and its progression at the earliest possible stages. Through advancements in the use of optical coherence tomography (OCT) and other technologies, the long-term goal of this research project ...

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    13. Celloptic Incorporated Receives NIH Grant for A New Holographic 3D Camera for Fundus Imaging

      Celloptic Incorporated Receives NIH Grant for A New Holographic 3D Camera for Fundus Imaging

      Celloptic Incorporated Receives a 2016 NIH Grant for $225,635 for A New Holographic 3D Camera for Fundus Imaging. The principal investigator is Gary Brooker. The program began in 2016 and ends in 2017. Below is a summary of the proposed work. A NEW HOLOGRAPHIC 3D CAMERA FOR FUNDUS IMAGING Abstract In the United States, retinal disease is the most common cause of visual impairment, with age-related macular degeneration (AMD) and diabetic retinopathy (DR) being the most common retinal diseases. For each of the above conditions, high resolution and three-dimensional (3D) imaging of the retina, retinal vasculature, choroid and/or ...

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    14. The University of Colorado at Denver Receives NIH Grant for Photonics Monitoring and Modeling Core

      The University of Colorado at Denver Receives NIH Grant for Photonics Monitoring and Modeling Core

      The University of Colorado at Denver Received at 2016 NIH Grant for $691,303 for Photonics Monitoring and Modeling Core. The principal investigator is Matthew Brenner. The program beghan in 2016 and ends in 2017. Below is a summary of the proposed work. The Photonics Monitoring and Modeling Core (PMMC) consists of three core photonics based novel diagnostic technologies and a highly monitored mid-size animal model (rabbit) testing facility based at the University of California, Irvine, Beckman Laser Institute that support investigations at UC Irvine, UC San Diego, and the University of Colorado. The Core will provide all investigators with ...

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    15. Laser thermal therapy monitoring using complex differential variance in optical coherence tomography

      Laser thermal therapy monitoring using complex differential variance in optical coherence tomography

      Conventional thermal therapy monitoring techniques based on temperature are often invasive, limited by point sampling, and are indirect measures of tissue injury, while techniques such as magnetic resonance and ultrasound thermometry are limited by their spatial resolution. The visualization of the thermal coagulation zone at high spatial resolution is particularly critical to the precise delivery of thermal energy to epithelial lesions. In this work, an integrated thulium laser thermal therapy monitoring system was developed based on complex differential variance (CDV), which enables the 2D visualization of the dynamics of the thermal coagulation process at high spatial and temporal resolution with ...

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    16. 15 Open PhD Positions within Supercontinuum Light Sources and Applications at Technical University of Denmark

      15 Open PhD Positions within Supercontinuum Light Sources and Applications at Technical University of Denmark

      We are seeking 15 skilled candidates for PhD positions across Europe in supercontinuum light sources and applications. The candidates should have a background in physics and interest in nonlinear optics, fibre optics and waveguides, and laser physics. SUPUVIR ( SUPercontinuum broadband light sources covering UV to IR applications ) is a new Innovative Training Network (ITN) funded by the European H2020 programme. SUPUVIR will focus on so-called supercontinuum laser sources, which essentially are laser sources emitting coherent laser light that is broadband enough to be considered white. The PhD students will be given extensive knowledge in silica and soft-glass chemistry, preform design ...

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    17. Opticent Incorporated Receives NIH Grant for Clinical Optical Coherence Tomography for Retina Metabolic Imaging

      Opticent Incorporated Receives NIH Grant for Clinical Optical Coherence Tomography for Retina Metabolic Imaging

      Opticent Incorporated Receives a 2016 NIH Grant for $224,139 for Clinical Optical Coherence Tomography for Retina Metabolic Imaging. The principal investigator is Andrew Radosevich. The program began in 2016 and ends in 2017. Below is a summary of the proposed work. The primary endpoint of this SBIR phase I proposal is to develop a method capable of monitoring retinal oxygen metabolism in patients undergoing treatment for vision-threatening diabetic retinopathy (DR) in the clinical Ophthalmology setting. I is estimated that by the year 2030 over 150 million individuals will suffer from DR worldwide. In its earliest form, DR is characterized ...

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    18. University of Washington Receives NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 2D Pathology of Pancreas

      University of Washington Receives NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 2D Pathology of Pancreas

      University of Washington Receives a 2016 NIH Grant for $235,226 for Needle Biopsy Preservation and Preparation for Rapid 2D Pathology of Pancreas. The principal investigator is Eric Seibel. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. There are over three million needle biopsies performed every year in the USA, typically for the diagnosis of breast, prostate, thyroid, lung, liver, and pancreatic cancers. Because needle biopsies are less invasive than surgical biopsies, they are much more cost-effective. However, a major limitation for all needle biopsies are that the pathologist or cytologist ...

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    19. University of North Carolina Receives NIH Grant for Imaging Nanophysical Properties of Actively Transporting Bronchial Mucus

      University of North Carolina Receives NIH Grant for Imaging Nanophysical Properties of Actively Transporting Bronchial Mucus

      University of North Carolina at Chapel Hill Receives a 2016 NIH Grant for $234,624 for Imaging Nanophysical Properties of Actively Transporting Bronchial Mucus. The principal investigator is Amy Oldenburg. The program began in 2016 and ends in 2018. Below is a summary of the proposed work. Mucus coats the lung epithelium and traps thousands of pathogens that we inhale every day. Human bronchial epithelial (hBE) cells lining the lung have cilia that propel mucus via shear forces, a mechanism known as muco-ciliary transport (MCT). MCT acts to clear mucus, providing a primary defense against trapped pathogens. In respiratory diseases ...

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    20. Jackson Laboratory Receives NIH Grant for Eye Mutan Resource

      Jackson Laboratory Receives NIH Grant for Eye Mutan Resource

      Jackson Laboratory Receives a 2016 NIH Grant for $437,500 for Eye Mutan Resource. The principal investigator is Bo Chang. The program began in 2010 and ends in 2019. Below is a summary of the proposed work. The main objective of the Eye Mutant Resource (EMR) is to identify, characterize, and preserve mice with genetically caused ocular disorders. Our purpose is to distribute these well-characterized models quickly and efficiently to support and promote vision research with the ultimate goal of advancing the elucidation, treatment, and cure of heritable eye diseases. Award of this grant is critical to the continuation of ...

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    21. Children's Hospital of Philadelphia Receives NIH Grant for Visual Outcome Measures in Children With Optical Pathway Gliomas

      Children's Hospital of Philadelphia Receives NIH Grant for Visual Outcome Measures in Children With Optical Pathway Gliomas

      Children's Hospital of Philadelphia Receives 2016 NIH Grant for $228,593 for Visual Outcome Measures in Children With Optical Pathway Gliomas. The principal investigator is Robert Avery. The program began in 2015 and ends in 2017. Below us a summary of the proposed work. This Mentored Patient-Oriented Research Career Development Award will prepare a pediatric neuroophthalmologist for an academic career as an independent multidisciplinary clinical researcher with a focus on vision outcomes in children with brain tumors of the visual pathway called optic pathway gliomas (OPGs). The candidate's application provides training needed to establish a clinical research career ...

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    22. Heads up displays for optical coherence tomography integrated surgical microscopes

      Heads up displays for optical coherence tomography integrated surgical microscopes

      Surgical microscope systems are provided including an optical coherence tomography (OCT) system; an objective lens; oculars for direct viewing of a subject distal to the objective lens; a heads up display module configured to direct an optical image through the oculars to be visible to a user of at least one ocular; and a coupling element connected to the surgical microscope coupling the OCT system, the heads up display module and the objective lens. The coupling element has first and second faces, the first face positioned toward the oculars of the surgical microscope and the second face positioned toward the ...

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    23. Physical Sciences Incorporated Receives NIH Grant for Hand-Held RCM/OCT Probe for Skin Cancer Laser Therapy Guidance

      Physical Sciences Incorporated Receives NIH Grant for Hand-Held RCM/OCT Probe for Skin Cancer Laser Therapy Guidance

      Physical Sciences Incorporated Receives a 2016 NIH Grant for $475,423 for Hand-Held RCM/OCT Probe for Skin Cancer Laser Therapy Guidance. The principal investigator is Nicusor Iftimia. The program began in 2011 and ends in 2017. Below is a summary of the proposed work. Physical Sciences, Inc. (PSI), in collaboration with Memorial Sloan Kettering Cancer Center (MSKCC) and Caliber Imaging & Diagnostics Inc. (Caliber ID), proposes to develop a hand-held reflectance confocal microscopy - optical coherence tomography (RCM-OCT) imaging probe and clinically evaluate its potential use for guiding laser ablation therapy of BCC basal cell carcinoma (BCC). While RCM provides en ...

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    24. Brigham and Women's Hospital Receives a NIH Grant for Aortic Valve Microcalicifacation

      Brigham and Women's Hospital Receives a NIH Grant for Aortic Valve Microcalicifacation

      Brigham and Women's Hospital Receives a 2016 NIH Grant for $415,740 for Aortic Valve Microcalicifacation. The principal investigator is Elena Aikawa. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. This research project will test the hypothesis that, in the diabetic milieu, S100A9 induces the calcification potential of valvular interstitial cell (VIC)-derived matrix vesicles, precursors of microcalcification, offering the novel mechanism of calcific aortic valve disease (CAVD). Our pilot studies showed that S100A9 - a recently identified biomarker of acute cardiovascular events - is expressed by VIC and a component of ...

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