1. Articles in category: Funding

    1-24 of 386 1 2 3 4 ... 14 15 16 »
    1. New York University School of Medicine Receives 2014 NIH Grant to Study Hyperspectral Imaging of the Normal and Age-Related Macular Degeneration Fundus

      New York University School of Medicine Receives  2014 NIH Grant to Study Hyperspectral Imaging of the Normal and Age-Related Macular Degeneration Fundus

      A team with world-class expertise in ophthalmic disease, imaging, retinal pathology, and biomedical engineering will utilize hyperspectral imaging to provide, for the first time, in vivo molecular probing, validated with histopathologic correlation, of age-related macular degeneration (AMD). Their system, a specially modified fundus camera harnessed to cutting-edge biomedical image analysis techniques, will revolutionize the field by identifying the distribution and spectral signature of the various chromophores and fluorophores associated with AMD lesions. Drusen, the hallmark lesions of AMD, are biochemically heterogeneous and are key to understanding this disease. However, their composition cannot be determined in vivo with even the current ...

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    2. University of Texas at Arlington Receives NIH Grant to Study All Optical Control and Monitoring of Neural Activity.

      University of Texas at Arlington Receives NIH Grant to Study All Optical Control and Monitoring of Neural Activity.

      University of Texas at Arlington Received at 2014 NIH Grant for $206,065 to Study All Optical Control and Monitoring of Neural Activity. The principal investigator is Samarendra Mohanty. The program began in 2014 and ends in 2015. Below is a summary of the propose work. Success of optogenetic intervention of neural activity requires optimization of delivery of genes encoding light sensitive proteins (opsins) to specific cells, and to record the changes in cells and tissue during optogenetic stimulation. The most-commonly used method for delivering opsin(s) is use of viral vector, which is prone to cause unexpected inflammatory responses ...

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    3. Tornado Spectral Systems Announces Investment by Beauvest & Roadmap Captial

      Tornado Spectral Systems Announces Investment by Beauvest & Roadmap Captial

      Strategic Growth Round to Accelerate Global Expansion of Process Analyzers and Spectrometers-On-Chip Tornado Spectral Systems Inc., an emerging tech company developing radically superior tools for measuring the chemical composition and structure of materials in real-time for a variety of demanding industrial processes, announced additional funding led by venture capital firms BeauVest and Roadmap Capital. The new investments will be used to finance Tornado’s continued growth in North America and globally. With proprietary optical and nanophotonic technologies that overcome the limitations of conventional spectroscopy-based analyzers, Tornado Spectral Systems has developed a new class of instruments that can acquire chemical signatures ...

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    4. Oregon Health & Science University Receives NIH Grant for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma

      Oregon Health & Science University Receives NIH Grant  for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma

      Oregon Health & Science University Receives a 2014 NIH Grant for $734,129 for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma. The principal investigator is David Huang. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness. Early diagnosis and close monitoring of glaucoma are important because the onset is insidious and the damage is irreversible. Advanced imaging modalities such as optical coherence tomography (OCT) have been used in the past 2 decades to improve the objective evaluation of glaucoma. OCT has higher axial spatial resolution ...

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    5. Oregon Health & Science University Receives 2014 NIH Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography

      Oregon Health & Science University Receives 2014 NIH  Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography

      Oregon Health & Science University Receives a 2014 NIH Grant for $713,409 for Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography. The principal investigator is David Huang. The program began in 2007 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) is a cross-sectional and 3-dimensional (3-D) imaging technology with very fine spatial resolution (5 um). This project develops the methods and software needed for high-precision OCT measurements of the eye to guide implant, laser, and transplant surgeries in the front part of the eye. In the proposed continuation of ...

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    6. Stanford University Receives Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives 2014 NIH Grant for $392,576 for Molecular Imaging of Protein Glycosylation in Living Subjects. The principal investigator is Adam De La Zerda. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic in time ...

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    7. Bioptigen Receives NIH Grant for Measuring Choroidal Blood Flow Imaging with Spectral Domain OCT

      Bioptigen Receives NIH Grant  for Measuring Choroidal Blood Flow Imaging with Spectral Domain OCT

      Bioptigen Receives 2014 NIH Grant for $223,583 for Measuring Choroidal Blood Flow Imaging with Spectral Domain OCT. The principal investigator is Eric Buckland. The program began in 2014 and ends in 2015. Below is a summary of the proposed work. Ophthalmic vascular diseases impact millions of Americans. Age-related macular degeneration and diabetic retinopathy are the two major diseases with a well- known vascular factor. The role of the vascular system in glaucoma and retinopathy of prematurity is more insidious. The vascular theory of glaucoma suggests that the blood supply to the eye is a contributory factor in glaucoma. Advanced ...

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    8. Johns Hopkins University Receives NIH Grant for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives NIH Grant  for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives a 2014 NIH Grant for $681,519 for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo. The principal investigator is Robert Brown. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. This Biomedical Research Partnership (BRP) proposal involves a partnership among a biomedical engineering team, a pulmonary physiology team, and a clinical pulmonary medicine team. This research program will incorporate state of the art optical engineering, advanced in vivo physiologic evaluation, and direct application to human obstructive lung diseases (OLD). Optical coherence tomography (OCT) is ...

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    9. Children's Research Institute Receives NIH Grant to Study Visual Outcome Measures in Children with Optic Pathway Gliomas

      Children's Research Institute Receives NIH Grant  to Study Visual Outcome Measures in Children with Optic Pathway Gliomas

      Children's Research Institute Received a 2014 NIH Grant for $229,113 to Study Visual Outcome Measures in Children with Optic Pathway Gliomas. The principal investigator is Robert Avery. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. This Mentored Patient-Oriented Research Career Development Award will prepare a pediatric neuroophthalmologist for an academic career as an independent multidisciplinary clinical researcher with a focus on vision outcomes in children with brain tumors of the visual pathway called optic pathway gliomas (OPGs). The candidate's application provides training needed to establish a clinical research ...

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    10. University of Arizona Receives NIH Grant for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention

      University of Arizona Receives NIH Grant for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention

      University of Arizona Receives a 2014 NIH Grant for $294,662 for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention. The principal investigator is Steven Stratton The program began in 2014 and ends in 2015 Below is a summary of the proposed work. Project 3 will test and clinically validate mechanisms and pharmacologic strategies explored in Projects 1-2, which target Akt-mTOR, AMPK-mTOR, and Fyn/RSK pathways. Advanced clinical/translational study of skin cancer carcinogenesis, biology, and pathophysiology will help reduce morbidity/ mortality, provide insight into keratinocyte signaling, and provide an easily-accessed human model of full-spectrum carcinogenesis for other ...

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    11. Columbia University Receives NIH Grant for Measures Of Human Receptor and Post Receptor Activity

      Columbia University Receives NIH Grant for Measures Of Human Receptor and Post Receptor Activity

      Columbia University Receives 2014 NIH Grant for $532,143 for Measures Of Human Receptor and Post Receptor Activity. The principal investigator is Donald Hood. The program began in 1991 and ends in 2016. Below is a summary of the proposed work. Our long-term objective has been to develop a set of noninvasive techniques for studying the human retina. By applying novel techniques and current theories of phototransduction to the full-field electroretinogram (ERG), we have successfully developed widely-used noninvasive techniques for studying the global activity of the rod and cone receptors, as well as the rod bipolar cells. These indices of ...

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    12. University of Washington Received a 2014 NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas

      University of Washington Received a 2014 NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas

      University of Washington Received a 2014 NIH Grant For $232,550 for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas. The principal investigator is Eric Seibel. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. There are over three million needle biopsies performed every year in the USA, typically for the diagnosis of breast, prostate, thyroid, lung, liver, and pancreatic cancers. Because needle biopsies are less invasive than surgical biopsies, they are much more cost-effective. However, a major limitation for all needle biopsies are that the pathologist or cytologist ...

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    13. UC Irvine Receives NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      UC Irvine Receives NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Received a 2014 NIH Grant for $598,705 for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging. The principal investigator is Zhongping Chen. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography (OCT), ultrasound (US), and phase-resolved acoustic radiation force optical coherence elastography (ARF-OCE). The multimodal intravascular imaging system is unique in that it combines the advantages of the high spatial resolution ...

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    14. Johns Hopkins University Receives NIH Grant to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer

      Johns Hopkins University Receives  NIH Grant to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer

      Johns Hopkins University Receives a 2014 NIH Grant for $47,676 to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer. The principal investigator is Carmen Kut. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. In brain cancers such as gliomas, aggressive removal of the solid tumor through surgery is associated with improved overall survival. In fact, i has been shown that at least 78% of the tumor has to be removed to make a meaningful difference in the patient's survival. Current techniques for tumor removal ...

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    15. Stanford University Receives a NIH grant for Enhanced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a NIH grant  for Enhanced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a 2014 NIH grant for $460,742 for Enhanced Clinical Diagnosis of Early Osteoarthritis. The principal investigator was Constance Chu. The program began in 2005 and ends in 2016. Below is a summary of the proposed work. Osteoarthritis is a leading cause of disability, and a major public health issue. Progressive loss of articular cartilage due to injury and degeneration are important etiological factors in the development of osteoarthritis. While laboratory studies show a potential to reverse pathological changes in articular cartilage prior to breakdown of the articular surface, a major barrier to clinical translation of these ...

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    16. University of Pittsburgh Receives a 2014 NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      University of Pittsburgh Receives a 2014 NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      University of Pittsburgh Receives a 2014 NIH Grant for $726,299 for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. The program began in 2000 and ends in 2019. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness and visual morbidity. Because the disease causes irreversible damage to neural tissue it is of utmost importance to identify glaucoma and its progression at the earliest possible stages. Through advancements in the use of optical coherence tomography (OCT) and other technologies, the long-term goal of this research project is to precisely ...

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    17. Johns Hopkins University Receives a 2014 NIH Grant for 3D Segmentation and Registration of Macular SD-OCT for Applications in Multiple Sclerosis

      Johns Hopkins University Receives a 2014 NIH Grant for 3D Segmentation and Registration of Macular SD-OCT for Applications in Multiple Sclerosis

      Johns Hopkins University Receives a 2014 NIH Grant for $387,284 for 3D Segmentation and Registration of Macular SD-OCT for Applications in Multiple Sclerosis. The principal investigator is Jerry Prince. Below is a summary of the proposed work. Vision is compromised in at least 55% of multiple sclerosis (MS) patients and may represent the very first manifestation of disease onset. Spectral domain optical coherence tomography (SD-OCT) enables in-vivo, high-resolution studies of the retina, and is increasingly being used as a biomarker in neurodegenerative diseases. SD-OCT has provided phenotypical measurements of the retinal nerve fiber layer, ganglion cell layer, and overall ...

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    18. Wasatch Photonics Receives an NIH SBIR Grant for Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives an NIH SBIR Grant for Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives an NIH SBIR Grant for $207,045 for Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications. The principal investigator is Roman Kuranov. The program began in 2014 and ends in 2015. Below is a summary of the proposed work. During this SBIR Phase I project we propose to build and test in phantoms a prototype of an innovative cost-effective Optical Coherence Tomography (OCT) system with a 10X increase in acquisition rate compared to commercially available systems. Further development may add an additional 10X increased acquisition rate for a total of 100X. Current market demand for Mega ...

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    19. UCSF received a NIH Grant for Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT

      UCSF received a NIH Grant for Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT

      University of California at San Francisco received a 2014 NIH Grant for $333,825 for Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT. The principal investigator is Daniel Fried. The program began in 2006 and ends in 2015. Below is a summary of the proposed work. The overall objective of this proposed research is to develop polarization sensitive optical coherence tomography (PS-OCT) as a non-invasive optical device for the accurate and early clinical assessment of tooth demineralization and remineralization. The central hypothesis underlying this proposal is that the depth-resolved changes in the magnitude of light scattering of dental hard tissues ...

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    20. Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic/ Case Western Reserve University Receiver 2014 NIH Grant for $203,124 for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery. The principal investigator is Justis Ehlers. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Optical coherence tomography (OCT) has revolutionized the management of ophthalmic diseases with the precise anatomic information it provides with non-invasive imaging. The high-resolution cross-sectional tissue details make OCT a natural complement to ophthalmic surgery. Intraoperative OCT (iOCT) has the potential to provide real-time feedback to surgeons thus improving surgical care and outcomes. This research activity will ...

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    21. Yale University Receives NIH Grant for Massively Parallel Interferometric Confocal Microscopy using Degenerate Lasers

      Yale University Receives  NIH Grant  for Massively Parallel Interferometric Confocal Microscopy using Degenerate Lasers

      Yale University Receives 2014 NIH Grant for $209,850 for Massively Parallel Interferometric Confocal Microscopy using Degenerate Lasers. The principal nvestigator is Michael Choma. Below is a summary of the proposed work. Confocal microscopy uses geometric principles to generate cross-sectional images of scattering biological tissue. Traditional reflectance confocal microscopes use serial pixel acquisition, thereby limiting acquisition speeds. Parallelization of pixel acquisition would dramatically increase imaging speeds and enable the study of new kinds of physiology. For example, massively parallelized reflectance confocal microscopy would be invaluable in the emerging field of cilia-driven mucus physiology in the respiratory system. Indeed, in terms ...

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    22. Massachusetts General Hospital Receives NIH Grant for The Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives NIH Grant for The Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives 2014 NIH Grant For $1,449,151 for The Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) has evolved into a powerful microscopy technique for a broad range of applications in biology and clinical medicine. It can safely be used to image biological tissue with high resolution and can easily integrate flexible, narrow diameter optical fiber probes for imaging internal organs. Recent advances have increased OCT imaging speeds by nearly ...

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    23. University of California at San Diego Receives at 2014 NIH Grant for Computational Ophthalmology

      University of California at San Diego Receives at 2014 NIH Grant for Computational Ophthalmology

      University of California at San Diego Receives at 2014 NIH Grant for $188,364 for Computational Ophthalmology. The principal investigator is Linda Zangwill. The program began in 2014 and ends in 2014. Below is a summary of the proposed work. COMPUTATIONAL OPHTHALMOLOGY MODULE OVERVIEW At UCSD, structural imaging instruments such as the spectral domain optical coherence tomography (SD-OCT) and functional instruments are used extensively in animal (Drs. Weinreb, Freeman, Yu, La Spada, Zhang, Freeman) and human studies of glaucoma (Drs. Weinreb, Ju, Lindsay, Zangwill, Medeiros, Balasubramanian) and retinal disease (Drs. Freeman, Yu, Bartsch, Zhang, Cheng). The recent development and commercialization ...

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    24. University of California at San Diego receives NIH Grant for Studying Animal Structure and Function

      University of California at San Diego receives NIH Grant for Studying Animal Structure and Function

      University of California at San Diego received a 2014 NIH Grant for $167,628 for Animal Structure and Function. The principal investigator is Dirk-Uwe Bartsch. The program began in 2014 and ends in 2015. Below is a summary of the proposed work. The Animal Structure and Function Module will provide new centralized space for state-of-the-art structural and functional animal testing with a dedicated animal care technician to conduct the testing and to train investigators and their staff on the use of the new equipment. The recent growth in the number of faculty in the Department of Ophthalmology conducting animal structure ...

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