1. Articles in category: Funding

    1-24 of 523 1 2 3 4 ... 20 21 22 »
    1. EU Funded Careioca Projet Lead to New High-Speed Ex-Vivo and Endoscopic Optical Imaging Systems for Real-Time Cancer Diagnosis Showing High Potential

      EU Funded Careioca Projet Lead to New High-Speed Ex-Vivo and Endoscopic Optical Imaging Systems for Real-Time Cancer Diagnosis Showing High Potential

      Cancer diagnosis relies on the long and complex histology process. During surgery, there is currently no real- time guidance at the histology level, leading to up to 40% of reoperations . Along the cancer care workflow , in particular for tumor biopsy and excision, current existing preoperative and intraoperative imaging techniques fail to perform a reliable in situ diagnosis. Moreover, the complete pathological diagnosis, often based on histology slides preparation, is usually only available after a few days. For these reasons a significant number of patients need to undergo secondary biopsy or surgery. The CAReIOCA project combined the latest advances in CMOS ...

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    2. An implant to catch metastatic cancer cells before they grow into tumors

      An implant to catch metastatic cancer cells before they grow into tumors

      There could be a way around this, though: a special imaging method under development at Northwestern University called Inverse Spectroscopic Optical Coherence Tomography (ISOCT). ISOCT detects molecular-level differences in the way cells in the body scatter light. And when we scan our implant with ISOCT, the light scatter pattern looks different when it's full of normal cells than when cancer cells are present. In fact, the difference is apparent when even as few as 15 out of the hundreds of thousands of cells in the implant are cancer cells. There's a catch – ISOCT cannot penetrate deep into tissue ...

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    3. Oregon Health and Science University Receives NIH Grant for Ossicle Vibration Measurement sin Conductive Hearing Loss

      Oregon Health and Science University Receives NIH Grant for Ossicle Vibration Measurement sin Conductive Hearing Loss

      Oregon Health and Science University Receives a 2016 NIH Grant for $418,717 for Ossicle Vibration Measurement sin Conductive Hearing Loss. The principal investigator is Steven Jaques. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. The proposal develops a hand-held otoscope that uses optical coherence tomography (OCT) to image the tympanic membrane and ossicles behind an intact tympanic membrane. The system is based on spectral Fourier-domain OCT and can measure vibrations of the ossicles (malleus, incus, stapes) of the middle ear on the scale of nm to ¿m amplitude. In Aim ...

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    4. University of Iowa Receives NIH Grant for 3D Image Analysis Approach to Determine Severity and Cause of Optic Nerve Edema

      University of Iowa Receives NIH Grant for 3D Image Analysis Approach to Determine Severity and Cause of Optic Nerve Edema

      University of Iowa Receives a 2016 NIH Grant for $339,750 for 3D Image Analysis Approach to Determine Severity and Cause of Optic Nerve Edema. The principal investigator is Mona Garvin. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Currently, the clinical assessment of optic nerve swelling is limited by the subjective ophthalmoscopic evaluation by experts in order to diagnose and differentiate the cause of the optic disc edema. The long-term goal of our research effort is to develop automated 3D image-analysis approaches for the identification of an optimal set of ...

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    5. Massachusetts Institute of Technology Receives Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Receives Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Receives a 2016 NIH Grant for $288,576 for Optical Biopsy Using Optical Coherence Tomography. The principal investigator is James Fujimoto. The program began in 1997 and ends in 2019. Below is a summary of the proposed work. This is a multidisciplinary collaboration between investigators at the Massachusetts Institute of Technology and the VA Boston Healthcare System integrating imaging technology research, clinical imaging studies, medical device development and animal imaging studies. Esophageal cancer is a lethal malignancy, with a five-year survival rate of 16%. Barrett's esophagus (BE) and dysplasia are precursors to esophageal adenocarcinoma (EAC ...

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    6. Massachusetts General Hospital Receives NIH Grant for Octology: Histology using Optical Coherence Tomography

      Massachusetts General Hospital Receives NIH Grant for Octology: Histology using Optical Coherence Tomography

      Massachusetts General Hospital Receives a 2016 NIH Grant for $253,600 for Octology: Histology using Optical Coherence Tomography. The principal investigator is Burce Fischl. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. While histology remains the gold standard for assessing human neuroanatomy, the procedures for sectioning and hand mounting tissue for microscopic imaging are not substantially different than they were 100 years ago. These steps introduce irremediable distortions into the tissue sections making it difficult or impossible to align sections with suffiient accuracy to create 3D histological volumes at the micron ...

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    7. Columbia University Receives NIH Grant for Structural and Functional Progression for Glaucomatous Damage to Macula

      Columbia University Receives NIH Grant for Structural and Functional Progression for Glaucomatous Damage to Macula

      Columbia University Receives a 2016 NIH Grant for $400,000 for Structural and Functional Progression for Glaucomatous Damage to Macula. The principal investigator is Carlos De Moraes. The program began in 2015 and ends in 2018. Below is a summary of the proposed work. There is compelling evidence that glaucomatous damage to the macula occurs even in early stages of the disease. The macula comprises about 30% of all retinal ganglion cells and its information corresponds to over 50% of the visual cortex. However, glaucomatous damage to the macula is often missed in clinical practice. Some of the reasons are ...

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    8. University of California at Irvine Receives NIH Grant for Phased Resolved ARF optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Receives NIH Grant for Phased Resolved ARF optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Receives a 2016 NIH Grant for $721,594 for Phased Resolved ARF optical Coherence Elastography for Intravascular Imaging. The principal investigatoor is Zhonping Chen. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography (OCT), ultrasound (US), and phase-resolved acoustic radiation force optical coherence elastography (ARF-OCE). The multimodal intravascular imaging system is unique in that it combines the advantages of the high spatial resolution ...

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    9. Northwestern University Receives a 2016 NIH Grant for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography

      Northwestern University Receives a 2016 NIH Grant for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography

      Northwestern University Receives a 2016 NIH Grant for $48,576 for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography. The principal investigator is Brian Soetikno. The program began in 2016 and ends in 2021. Below is a summary of the proposed work.

      The retina is one of the most metabolically active tissues in the human body, making it particularly susceptible to hypoxia. In diabetic retinopathy (DR), aberrant oxygen metabolism has been hypothesized to play a pivotal role its pathogenesis. An improved understanding of how imbalances in oxygen delivery and demand lead to the progression of DR ...

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    10. Iowa City Veterans Administration Medical Center Received a 2016 NIH Grant for Automated Assessment of Optical Edema with Low-Cost Imaging

      Iowa City Veterans Administration Medical Center Received a 2016 NIH Grant for Automated Assessment of Optical Edema with Low-Cost Imaging

      Iowa City Veterans Administration Medical Center Received a 2016 NIH Grant for Automated Assessment of Optical Edema with Low-Cost Imaging. The principal investigator is Mona Garvin. The program began in 2017 and ends in 2020. Below is a summary of the proposed work. Papilledema - a specific type of optic nerve edema associated with elevated intracranial pressure - occurs in veterans due to intracranial masses or hemorrhage, obstructive hydrocephalus, following traumatic brain injury, and from idiopathic causes. Currently, the diagnosis of papilledema and its severity are assessed by direct funduscopic observation or digital fundus photographs using a six-stage grading scale. The scale ...

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    11. Valery Tuchin Honored with Joseph W. Goodman Award for Book on Light Scattering Applications in Medical Diagnostics

      Valery Tuchin Honored with Joseph W. Goodman Award for Book on Light Scattering Applications in Medical Diagnostics

      Valery Tuchin of Saratov State University (SSU) is the recipient of the 2016 Joseph W. Goodman Book Writing Award for his book titled Light Scattering Methods and Instruments for Medical Diagnosis, 3rd ed., published by SPIE Press in 2015. The award is co-sponsored by SPIE, the international society for optics and photonics , and The Optical Society. The Goodman Award , a biennial award funded by a personal gift from Joseph W. and Hon Mai Goodman, recognizes a recent and outstanding book in the field of optics and photonics that has contributed significantly to research, teaching, or the optics and photonics industry ...

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    12. Five finalists compete for Nvidia 2016 Global Impact Award this week

      Five finalists compete for Nvidia 2016 Global Impact Award this week

      The fourth finalist group is Joseph Izatt and his team at Duke University for their work in using GPU-accelerated, real-time stereoscopic 3D data for eye surgery. A single Titan GPU takes a stream of raw “optical coherence tomography” (OCT) data, processes it, and renders 3D volumetric images. These images, at a resolution of a few micrometers, are projected into microscope eyepieces. With Nvidia 3D Vision-ready monitors and 3D glasses, live stereoscopic data can be viewed by both a surgeon using the microscope and a group observing the operation as it occurs. The blog post is titled “How GPUs Help Eye ...

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    13. MIT receives a NIH grant for Novel Diagnostics with Optical Coherence Tomography.

      MIT receives a NIH grant for Novel Diagnostics with Optical Coherence Tomography.

      Massachusetts Institute of Technology receives a 2016 NIH grant for $437,893 for Novel Diagnostics with Optical Coherence Tomography. The principal investigator is James Fujimoto. The program began in 1985 and ends in 2020. Below is a summary of the propose work. This proposal is a resubmission of a competing renewal application for an ongoing collaborative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye Center. This is a multidisciplinary program which integrates imaging technology research, clinical and small animal imaging studies. The specific aims are: Aim 1. Next ...

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    14. Duke University Receives NIH Grant for Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care

      Duke University Receives NIH Grant  for Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care

      Duke University Receives a 2016 NIH Grant for $691,728 for Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care. The principal investigator is Cynthia Toth. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that may impact vision in vulnerable preterm neonates for a lifetime. Clinical care of infants with ROP decreases the likelihood of blindness, but abnormal vision is common, especially in those with disease severe enough to require treatment. Because it has ...

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    15. Recanalization system using radiofrequency energy

      Recanalization system using radiofrequency energy

      A method and systems for treating chronic total occlusions, particularly those that are difficult to treat, is disclosed. In this approach, recanalizing the CTO is achieved using a combined antegrade and retrograde approach. The proximal end of the occlusion is penetrated using an antegrade wire, using a traditional approach. Using collateral vessels, the distal end of the occlusion is crossed in a retrograde fashion. By appropriately maneuvering each member and applying radiofrequency energy between the proximal and distal ends of the occlusion, a continuous channel is created.

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      Mentions: Osamu Katoh
    16. Emanuel Hospital Receives a 2016 NIH Grant for Optic Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital Receives a 2016 NIH Grant for Optic Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital Receives a 2016 NIH Grant for $559,400 for Optic Nerve Head SD-OCT Imaging in Glaucoma. The principal investigator is Claude Burgoyne. The program began in 2010 and ends in 2017. Below is a summary of the proposed work. As a result of discoveries made during the first project period, we propose a paradigm change for clinical assessment of the Optic Nerve Head (ONH), peripapillary retinal nerve fiber layer (RNFL) and macula based on acquisition and regionalization of Spectral Domain Optical Coherence Tomography (SDOCT) ONH, RNFL and macula datasets relative to the axis between the center of Bruch ...

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    17. Method for measuring an eye

      Method for measuring an eye

      A method for measuring the axial length of an eye using optical coherence tomography, during which a plurality of A-scans of the OCT measurement are combined to an axial length, taking into account the alignment with which they were obtained, and taking into account the topography of the cornea. The distance of the front of the cornea from the retina is determined using OCT while measuring or controlling the alignment of the measuring device to the eye in that the topography of the front of the cornea is measured or made available. The calculation of an axial length from an ...

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    18. The Volkswagen Foundation Grant In Biomedical Engineering

      The Volkswagen Foundation Grant In Biomedical Engineering

      The Volkswagen Foundation Grant in Biomedical Engineering . Scientists increasingly succeed in simulating processes of life within artificial systems or in developing novel artificial systems based on fundamental principles of life. These approaches seek a better understanding of fundamental principles of life, and in doing so they open up intriguing and novel perspectives on life to complement the philosophical view. With its initiative, The Volkswagen Foundation aims to support unique and excellent projects at the interface between the natural and life sciences with this particular focus. In view of the ambitious nature of this kind of research the Volkswagen Foundation is ...

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    19. Chicago startup raises $3M for probe to prevent repeat cancer surgeries

      Chicago startup raises $3M for probe to prevent repeat cancer surgeries

      A c hicago-based company has raised $3.1 million to fund a clinical trial for its high-resolution imaging probes for cancer surgeons. Diagnostic Photonics, which launched in 2011 at the University of Illinois at Urbana-Champaign, hopes its technology will prevent multiple surgeries for cancer patients. The company is focusing efforts first on breast cancer because about 25 percent of affected women undergo multiple surgeries after lumpectomy, according to a study conducted by the University of Wisconsin Carbone Cancer Center in Madison. The repeat surgeries are often spurred by the “challenges of where does the cancer stop and normal tissues start ...

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    20. MedLumics Appoints Cardiovascular Device Expert Tim Lenihan to Board of Directors

      MedLumics Appoints Cardiovascular Device Expert Tim Lenihan to Board of Directors

      MedLumics , a cardiology device company specializing in the application of advanced optical coherence tomography (OCT) technology, has announced the appointment of cardiovascular device veteran Tim Lenihan to its board of directors. With vast experience in field of electrophysiology, Lenihan will help guide the continued advancement of the company’s catheter ablation technology for the treatment of atrial fibrillation. “We are very fortunate to add Tim to our board of directors given his domain expertise in catheter-based medical technologies, specifically in the cardiac ablation field,” said Eduardo Margallo, CEO of MedLumics. “His experience and insights will undoubtedly make an enormous contribution ...

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    21. University of Alabama Receives NIH Grant for In Vivo Ultrastructure of Chorioretinal Disease

      University of Alabama Receives NIH Grant  for In Vivo Ultrastructure of Chorioretinal Disease

      University of Alabama at Birmingham Receives a 2016 NIH Grant for $330,750 for In Vivo Ultrastructure of Chorioretinal Disease. The principal investigator is Yuhua Zhang. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. Age-related macular degeneration (AMD) is a leading cause of vision loss in more than 10 million older Americans. For decades, AMD has been characterized by accumulation of extracellular lesions called drusen on the inner surface of Bruch's membrane (BrM), posterior to the retinal pigment epithelium (RPE), in a compartment called the sub-RPE space. Drusen are now ...

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    22. University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure of Fetal Brain Development

      University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure of Fetal Brain Development

      University of Houston Receives a 2016 NIH Grant for $424,849 for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure of Fetal Brain Development. The principal investigator is Kirill Larin. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The overall objective of this study is to develop an optical coherence tomography (OCT) based high- resolution mouse embryonic brain imaging and analysis approach, and to use this method in correlation with molecular analysis to understand the interplay between ethanol (EtOH) and nicotine (NIC) effects on embryonic brain development. Maternal exposures to ...

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    23. University of California at Davis Receives NIH Grant for Properties of Photoreceptors and Muller Cells Investigated with AO-OCT

      University of California at Davis Receives NIH Grant for Properties of Photoreceptors and Muller Cells Investigated with AO-OCT

      University of California at Davis Receives a 2016 NIH Grant for $97,834 for Properties of Photoreceptors and Muller Cells Investigated with AO-OCT. The principal investigator is Ravi Jonnal. Below is a summary of the propose work. The research proposed for this award will examine functional and structural properties of single cells in the human retina. The three Aims will link the candidate's scientific background and career plans to study the human retina using a combination of adaptive optics (AO) and optical coherence tomography (OCT) which provide high lateral and high axial resolution, respectively (~2.5 μm in all ...

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    24. Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery

      Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery

      Duke University Receives a 2016 NIH Grant for $854,457 for Intraoperative OCT Guidance of Intraocular Surgery. The princial investigator is Joeseph Izatt. The program began in 2013 and ends in 2016. Belwo is a summary of the proposed work. This Bioengineering Research Partnership proposal brings together a team of experts in ophthalmic imaging and surgery to advance the state of the art in image-guided surgical interventions. We seek to overcome limitations to the surgeon's current stereo microscopic view of ocular structures by bringing optical coherence tomography (OCT) technology, which is already well accepted in ophthalmic practice, into the ...

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