1. Articles in category: Funding

    1-24 of 461 1 2 3 4 ... 18 19 20 »
    1. University of Alabama at Birmingham Receives NIH Grant to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT.

      University of Alabama at Birmingham Receives NIH Grant to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT.

      The University of Alabama at Birmingham Receives a 2015 NIH Grant for $498,330 to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT. The principal investigator is Steven Mark Rowe. The program began in 2012 and elndsi nin 2016. Below is a summary of the proposed work. Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), an anion transporter of chloride and bicarbonate. Defective or deficient CFTR leads to severe mucoobstructive lung disease and severe morbidity and early mortality due to lung infections. Even though substantial advances in ...

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    2. FedDev Ontario Supports Commercialization of Perimeter Medical Imaging’s OTIS™ Surgical Tissue Imaging System

      FedDev Ontario Supports Commercialization of Perimeter Medical Imaging’s OTIS™ Surgical Tissue Imaging System

      Perimeter Medical Imaging, Inc., a developer of real time imaging systems for in-surgery tumour margin assessment, today announced it is receiving up to $980,000 from the Government of Canada through the Federal Economic Development Agency for Southern Ontario (FedDev Ontario). The announcement was made at Perimeter’s new location in Toronto by John Carmichael, Member of Parliament for Don Valley West, on behalf of the Honourable Gary Goodyear, Minister of State for the Federal Economic Development Agency for Southern Ontario (FedDev Ontario). This investment will support the next phase of product and clinical development as well as accelerate regulatory ...

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    3. Case Western Reserve University Receives NIH Grant for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging

      Case Western Reserve University Receives NIH Grant for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging

      Case Western Reserve University Receives a 2015 NIH grant for $198,125 for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging. The principal investigator is Andrew Rollins. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. The long-term goal of this research program is to develop catheter-based optical coherence tomography (OCT) imaging tools that will improve the care of patients suffering from cardiac arrhythmias. This project aims to improve radiofrequency ablation (RFA) therapy, which is the standard of care for many arrhythmias, by providing microscopic image guidance at the tip of the ...

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    4. Johns Hopkins University Receives NIH Grant for Studying OCT to Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer.

      Johns Hopkins University Receives NIH Grant for Studying OCT to Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer.

      Johns Hopkins University Receives a 2015 NIH Grant for $48,120 for OCT to Distinguish B/T Tumor &Non-Tumor Tissue in Infiltrating Brain Cancer. The principal investigator is Carmen Kut. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. In brain cancers such as gliomas, aggressive removal of the solid tumor through surgery is associated with improved overall survival. In fact, i has been shown that at least 78% of the tumor has to be removed to make a meaningful difference in the patient's survival. Current techniques for tumor removal are ...

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    5. Assessment of Cardiac Allograft Vasculopathy by Optical Coherence Tomography

      Assessment of Cardiac Allograft Vasculopathy by Optical Coherence Tomography

      Cardiac allograft vasculopathy (CAV) is characterized by marked intimal proliferation and concentric vascular thickening and fibrosis. CAV remains the leading cause of late morbidity and mortality in heart transplant recipients. Optical coherence tomography (OCT) is a new generation catheter-based modality that acquires images at a spatial resolution of 10-20 μm which is 10-fold greater than that of intravascular ultrasound (IVUS). OCT is currently the most sensitive imaging technique for early CAV detection. Recent studies proved that circulating human leukocyte antigen (HLA) directed donor-specific antibodies correlate with increased mortality and CAV. Contradiction of scientific results has been reported regarding increased resting ...

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    6. Massachusetts General Hospital Receives NIH grant for the center for Biomedical OCT Research and Translation.

      Massachusetts General Hospital Receives  NIH grant for the center for Biomedical OCT Research and Translation.

      Massachusetts General Hospital Receives a 2015 NIH grant for $1,086,563 for the Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) has evolved into a powerful microscopy technique for a broad range of applications in biology and clinical medicine. It can safely be used to image biological tissue with high resolution and can easily integrate flexible, narrow diameter optical fiber probes for imaging internal organs. Recent advances have increased OCT imaging speeds by ...

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    7. Stanford University Receives NIH Grant to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives  NIH Grant  to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a 2015 NIH Grant for $461,667 to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis. The principal investigator is Constance Chu. The program began in 2005 and ends in 2016. Below is a summary of the proposed work. Osteoarthritis is a leading cause of disability, and a major public health issue. Progressive loss of articular cartilage due to injury and degeneration are important etiological factors in the development of osteoarthritis. While laboratory studies show a potential to reverse pathological changes in articular cartilage prior to breakdown of the articular surface, a major barrier to clinical translation of ...

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    8. UIUC Receives a NIH Grant for a Partnership for Primary Care Imaging

      UIUC Receives a NIH Grant for a Partnership for Primary Care Imaging

      University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $925,920 for a Partnership for Primary Care Imaging. The principal investigaror is Stephen Boppart. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Primary Care Medicine, including Family Practice and Pediatrics, has traditionally relied on physical exam skills and simplistic instruments for critical diagnostic decision making, monitoring, and referral to medical specialists. The otoscope and ophthalmoscope are two historical and ubiquitous instruments that largely only illuminate and magnify tissue surfaces in the ear and eye, respectively. This Partnership will develop a ...

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    9. University of California Riverside Receives NIH Grant to Study Optical Detection of the Pre-Seizure State.

      University of California Riverside Receives NIH Grant to Study Optical Detection of the Pre-Seizure State.

      University of California Riverside received a 2015 NIH Grant for $441,942 to Study Optical Detection of the Pre-Seizure State. The principal investigator is Kevin Binder. The program began in 2013 and ends in 2016. Below is a summary of the proposed work. Reliable means of detecting changes which occur during the "pre-seizure state" could serve as a method of seizure prediction, a benchmark in epilepsy research (NIH Curing Epilepsy Conferences, 2000 and 2007). Our preliminary data indicate pre-seizure constriction in brain extracellular space (ECS) accompanied by reduction in near-infrared (NIR) optical scattering prior to detection of seizure by electroencephalography ...

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      Mentions: UC Riverside
    10. UIUC Receives NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      UIUC Receives NIH Grant  for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      The University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $490,333 for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins. The principal investigator is Stephen Boppart. The program begain in 2012 and ends in 2017. Below is a summary of the proosed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving surgeries or lumpectomies are routinely performed. Currently, the surgeon is unable to visualize the microscopic structure at the margin, and conventionally relies on post-operative histological assessment of surgical margins to ...

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    11. On the road to ubiquity

      On the road to ubiquity

      When the National Science Foundation (NSF) was founded in 1950, the laser didn't exist. Some 65 years later, the technology is ubiquitous. As a tool, the laser has stretched the imaginations of countless scientists and engineers, making possible everything from stunning images of celestial bodies to high-speed communications. Once described as a "solution looking for a problem," the laser powered and pulsed its way into nearly every aspect of modern life. For its part, NSF funding enabled research that has translated into meaningful applications in manufacturing, communications, life sciences, defense and medicine. NSF also has played a critical role ...

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    12. MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      Massachusetts General Hospital Receives a 2015 NIH Grant for $472,417 To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. Barrett's esophagus (BE) is a condition where normal esophageal squamous mucosa changes to metaplastic columnar mucosa in response to chronic acid reflux. BE can progress to esophageal adenocarcinoma (EAC), a prevalent (~12,000 cases per year) and deadly cancer (~15% 5-year mortality rate). Current BE management strategies of anti-reflux therapy, endoscopic screening, and regular endoscopic biopsy surveillance and ablation therapy ...

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    13. MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      Massachusetts General Hospital Receives a 2015 NIH Grant for $733,578 to Study Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function. The principal investigator is David Sosnovik. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. Pressure overload of the left and right ventricles initially leads to adaptive hypertrophy. This, however, is frequently followed by maladaptive hypertrophy, heart failure and death. We hypothesize here that changes in 3D myocardial fiber architecture play a significant role in the deleterious transition from adaptive to maladaptive hypertrophy and heart failure. We further hypothesize ...

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    14. Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives a 2015 NIH Grant for $359,023 for Integrated Imaging of the Form and Function of the Beating Embryonic Heart. The principal investigator is Andrew Rollins. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Congenital heart defects (CHDs) afflict 36,000 babies born in the US each year and survivors often require several surgical interventions in their shortened lifetime. Despite continuous efforts, the mechanisms leading to CHDs remain largely unclear. In part, this is because most developmental cardiology studies fail to address the influential role of altered ...

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    15. Stanford University Receives NIH Grant to study Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives NIH Grant to study Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives a 2015 NIH Grant for $392,576 to study Molecular Imaging of Protein Glycoslation in Living Subjects. The principal investigator is Adan De La Zerda. The program began in 2012 and ends in 2017. Below is a summary of the propose work. The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic ...

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    16. Johns Hopkins University Receives NIH Grant to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives NIH Grant  to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives a 2015 NIH Grant for $782,083 to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo. The principal investigator is Robert Brown. The program began in 2014 and ends in 2019. Below is a summary of the proposed work.

      This Biomedical Research Partnership (BRP) proposal involves a partnership among a biomedical engineering team, a pulmonary physiology team, and a clinical pulmonary medicine team. This research program will incorporate state of the art optical engineering, advanced in vivo physiologic evaluation, and direct application to human obstructive lung diseases (OLD). Optical coherence tomography (OCT ...

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    17. Optical coherence tomography 'reducing heart attacks'

      Optical coherence tomography 'reducing heart attacks'

      APPLICATIONS < Previous | Next > | Table of Contents Optical coherence tomography 'reducing heart attacks' 21 May 2015 Imaging technique appears to improve outcomes for cardiac patients being fitted with coronary stents, finds large-scale trial. OCT guidance Clinical trials to assess the effectiveness of optical coherence tomography (OCT) imaging ahead of cardiac stent surgery is helping physicians make better interventions, and leading to better patient outcomes – including a reduced rate of heart attacks. That’s according to St Jude Medical (SJM) , the US-based medical equipment company whose OCT technology is currently the subject of two large-scale studies. In those trials, conducted on more ...

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    18. Avinger Announces 30-Day VISION Trial Results At EuroPCR 2015

      Avinger Announces 30-Day VISION Trial Results At EuroPCR 2015

      Avinger, Inc., (Nasdaq:AVGR) a developer and manufacturer of image-guided, catheter-based systems for the treatment of peripheral arterial disease (PAD) and pioneer of the lumivascular approach to treating vascular disease, today announced 30-day interim results for its VISION clinical study. VISION is designed to evaluate the safety and efficacy of the Pantheris™ system to perform directional atherectomy, while for the first time ever allowing physicians to use real-time intravascular imaging to aid in the removal of plaque from diseased lower extremity arteries. Results were presented by Arne Schwindt, M.D. of St. Franziskus Hospital in Muenster, Germany at the EuroPCR ...

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    19. University of Alabama Receives NIH Grant for Developing a Clinical and Translation Core Related to Cystic Fibrosis

      University of Alabama Receives NIH Grant  for Developing a Clinical and Translation Core Related to Cystic Fibrosis

      University of Alabama Receives a 2015 NIH Grant for $193,380 for Developing a Clinical and Translation Core related to Cystic Fibrosis. The principal investigator is steven Rowe. The program began in 2015 and ends in 2016. Below is a summary of the proposed work. Numerous investigators within the current P30 application have indicated a need for 1) primary human airway epithelial cells (from lung transplantation) or nasal epithelial cells from CF and non-CF individuals; 2) measurements of the functional anatomy of respiratory epithelia that track airway surface liquid homeostasis, ciliary beating, and mucociliary transport; or 3) CFTR bioelectric assays ...

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    20. University of Maryland Receives NIH Grant for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds

      University of Maryland Receives NIH Grant for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds

      University of Maryland Receives a 2015 NIH Grant for $320.744 for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds. The principal investigator is Yu Chen. Below is a summary of the propose work. Three-dimensional (3D) cell-based tissue grafts have been increasingly useful in tissue engineering and regenerative medicine. A critical building block in tissue engineering is the scaffold which can act as the supporting medium to deliver cell populations and induce the ingrowth of vessels and surrounding tissues. Therefore, it is necessary to develop tools to characterize the architecture of the scaffold. In addition, to study ...

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    21. Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients.

      Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients.

      Massachusetts General Hospital Received a 2015 NIH Grant for $780,355 for Intracoronary Imaging of Plaque Collagen in Patients. The principal investigator is Seemantini Nadkarni. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The goal of this proposal is to develop and validate an intracoronary imaging device for the assessment of plaque collagen content and architecture in patients. Acute myocardial infarction (AMI), caused by the rupture of unstable plaque, is the leading cause of death worldwide. Collagen and vascular smooth muscle cells (vSMCs) together impart mechanical stability to a plaque, and ...

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    22. University of Iowa Receives NIH grant for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema

      University of Iowa Receives  NIH grant for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema

      University of Iowa Received a 2015 NIH grant for $332,955 for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema. The principal investigator is Mona Garvin. The program began in 2013 and ends in 12018. Below is a summary of the proposed work. Currently, the clinical assessment of optic nerve swelling is limited by the subjective ophthalmoscopic evaluation by experts in order to diagnose and differentiate the cause of the optic disc edema. The long-term goal of our research effort is to develop automated 3D image-analysis approaches for the identification of an optimal set of ...

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    23. Massachusetts General Hospital Receives NIH Grant for OCTOLOGY: Histology Using Optical Coherence Tomography

      Massachusetts General Hospital Receives NIH Grant for OCTOLOGY: Histology Using Optical Coherence Tomography

      Massachusetts General Hospital Receives a 2015 NIH Grant for $217,500 for OCTOLOGY: Histology Using Optical Coherence Tomography. The principal investigator is Bruce Fischl. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. While histology remains the gold standard for assessing human neuroanatomy, the procedures for sectioning and hand mounting tissue for microscopic imaging are not substantially different than they were 100 years ago. These steps introduce irremediable distortions into the tissue sections making it difficult or impossible to align sections with suffiient accuracy to create 3D histological volumes at the micron ...

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    24. University of Maryland Receives NIH Grant for Identification of AF Ablation Targets via a Steerable Actuated Catheter

      University of Maryland Receives NIH Grant for Identification of AF Ablation Targets via a Steerable Actuated Catheter

      University of Maryland Receives a 2015 NIH Grant for $222,800 for Identification of AF Ablation Targets via a Steerable Actuated Catheter. The principal investigator is Jaydev Desai. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. Atrial fibrillation (AF) is the most common cardiac arrhythmia and has high patient morbidity, increases mortality two-fold, and increases health care costs. Each year, about 200,000 Americans are newly diagnosed with AF with a prevalence of several million in the U.S. alone. In the majority of cases, AF has been shown to originate ...

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    1-24 of 461 1 2 3 4 ... 18 19 20 »
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