1. Articles in category: Funding

    1-24 of 452 1 2 3 4 ... 17 18 19 »
    1. UIUC Receives NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      UIUC Receives NIH Grant  for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      The University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $490,333 for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins. The principal investigator is Stephen Boppart. The program begain in 2012 and ends in 2017. Below is a summary of the proosed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving surgeries or lumpectomies are routinely performed. Currently, the surgeon is unable to visualize the microscopic structure at the margin, and conventionally relies on post-operative histological assessment of surgical margins to ...

      Read Full Article
    2. On the road to ubiquity

      On the road to ubiquity

      When the National Science Foundation (NSF) was founded in 1950, the laser didn't exist. Some 65 years later, the technology is ubiquitous. As a tool, the laser has stretched the imaginations of countless scientists and engineers, making possible everything from stunning images of celestial bodies to high-speed communications. Once described as a "solution looking for a problem," the laser powered and pulsed its way into nearly every aspect of modern life. For its part, NSF funding enabled research that has translated into meaningful applications in manufacturing, communications, life sciences, defense and medicine. NSF also has played a critical role ...

      Read Full Article
    3. MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      Massachusetts General Hospital Receives a 2015 NIH Grant for $472,417 To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. Barrett's esophagus (BE) is a condition where normal esophageal squamous mucosa changes to metaplastic columnar mucosa in response to chronic acid reflux. BE can progress to esophageal adenocarcinoma (EAC), a prevalent (~12,000 cases per year) and deadly cancer (~15% 5-year mortality rate). Current BE management strategies of anti-reflux therapy, endoscopic screening, and regular endoscopic biopsy surveillance and ablation therapy ...

      Read Full Article
    4. MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      Massachusetts General Hospital Receives a 2015 NIH Grant for $733,578 to Study Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function. The principal investigator is David Sosnovik. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. Pressure overload of the left and right ventricles initially leads to adaptive hypertrophy. This, however, is frequently followed by maladaptive hypertrophy, heart failure and death. We hypothesize here that changes in 3D myocardial fiber architecture play a significant role in the deleterious transition from adaptive to maladaptive hypertrophy and heart failure. We further hypothesize ...

      Read Full Article
    5. Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives a 2015 NIH Grant for $359,023 for Integrated Imaging of the Form and Function of the Beating Embryonic Heart. The principal investigator is Andrew Rollins. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Congenital heart defects (CHDs) afflict 36,000 babies born in the US each year and survivors often require several surgical interventions in their shortened lifetime. Despite continuous efforts, the mechanisms leading to CHDs remain largely unclear. In part, this is because most developmental cardiology studies fail to address the influential role of altered ...

      Read Full Article
    6. Stanford University Receives NIH Grant to study Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives NIH Grant to study Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives a 2015 NIH Grant for $392,576 to study Molecular Imaging of Protein Glycoslation in Living Subjects. The principal investigator is Adan De La Zerda. The program began in 2012 and ends in 2017. Below is a summary of the propose work. The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic ...

      Read Full Article
    7. Johns Hopkins University Receives NIH Grant to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives NIH Grant  to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives a 2015 NIH Grant for $782,083 to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo. The principal investigator is Robert Brown. The program began in 2014 and ends in 2019. Below is a summary of the proposed work.

      This Biomedical Research Partnership (BRP) proposal involves a partnership among a biomedical engineering team, a pulmonary physiology team, and a clinical pulmonary medicine team. This research program will incorporate state of the art optical engineering, advanced in vivo physiologic evaluation, and direct application to human obstructive lung diseases (OLD). Optical coherence tomography (OCT ...

      Read Full Article
    8. Optical coherence tomography 'reducing heart attacks'

      Optical coherence tomography 'reducing heart attacks'

      APPLICATIONS < Previous | Next > | Table of Contents Optical coherence tomography 'reducing heart attacks' 21 May 2015 Imaging technique appears to improve outcomes for cardiac patients being fitted with coronary stents, finds large-scale trial. OCT guidance Clinical trials to assess the effectiveness of optical coherence tomography (OCT) imaging ahead of cardiac stent surgery is helping physicians make better interventions, and leading to better patient outcomes – including a reduced rate of heart attacks. That’s according to St Jude Medical (SJM) , the US-based medical equipment company whose OCT technology is currently the subject of two large-scale studies. In those trials, conducted on more ...

      Read Full Article
    9. Avinger Announces 30-Day VISION Trial Results At EuroPCR 2015

      Avinger Announces 30-Day VISION Trial Results At EuroPCR 2015

      Avinger, Inc., (Nasdaq:AVGR) a developer and manufacturer of image-guided, catheter-based systems for the treatment of peripheral arterial disease (PAD) and pioneer of the lumivascular approach to treating vascular disease, today announced 30-day interim results for its VISION clinical study. VISION is designed to evaluate the safety and efficacy of the Pantheris™ system to perform directional atherectomy, while for the first time ever allowing physicians to use real-time intravascular imaging to aid in the removal of plaque from diseased lower extremity arteries. Results were presented by Arne Schwindt, M.D. of St. Franziskus Hospital in Muenster, Germany at the EuroPCR ...

      Read Full Article
    10. University of Alabama Receives NIH Grant for Developing a Clinical and Translation Core Related to Cystic Fibrosis

      University of Alabama Receives NIH Grant  for Developing a Clinical and Translation Core Related to Cystic Fibrosis

      University of Alabama Receives a 2015 NIH Grant for $193,380 for Developing a Clinical and Translation Core related to Cystic Fibrosis. The principal investigator is steven Rowe. The program began in 2015 and ends in 2016. Below is a summary of the proposed work. Numerous investigators within the current P30 application have indicated a need for 1) primary human airway epithelial cells (from lung transplantation) or nasal epithelial cells from CF and non-CF individuals; 2) measurements of the functional anatomy of respiratory epithelia that track airway surface liquid homeostasis, ciliary beating, and mucociliary transport; or 3) CFTR bioelectric assays ...

      Read Full Article
    11. University of Maryland Receives NIH Grant for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds

      University of Maryland Receives NIH Grant for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds

      University of Maryland Receives a 2015 NIH Grant for $320.744 for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds. The principal investigator is Yu Chen. Below is a summary of the propose work. Three-dimensional (3D) cell-based tissue grafts have been increasingly useful in tissue engineering and regenerative medicine. A critical building block in tissue engineering is the scaffold which can act as the supporting medium to deliver cell populations and induce the ingrowth of vessels and surrounding tissues. Therefore, it is necessary to develop tools to characterize the architecture of the scaffold. In addition, to study ...

      Read Full Article
    12. Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients.

      Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients.

      Massachusetts General Hospital Received a 2015 NIH Grant for $780,355 for Intracoronary Imaging of Plaque Collagen in Patients. The principal investigator is Seemantini Nadkarni. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The goal of this proposal is to develop and validate an intracoronary imaging device for the assessment of plaque collagen content and architecture in patients. Acute myocardial infarction (AMI), caused by the rupture of unstable plaque, is the leading cause of death worldwide. Collagen and vascular smooth muscle cells (vSMCs) together impart mechanical stability to a plaque, and ...

      Read Full Article
    13. University of Iowa Receives NIH grant for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema

      University of Iowa Receives  NIH grant for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema

      University of Iowa Received a 2015 NIH grant for $332,955 for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema. The principal investigator is Mona Garvin. The program began in 2013 and ends in 12018. Below is a summary of the proposed work. Currently, the clinical assessment of optic nerve swelling is limited by the subjective ophthalmoscopic evaluation by experts in order to diagnose and differentiate the cause of the optic disc edema. The long-term goal of our research effort is to develop automated 3D image-analysis approaches for the identification of an optimal set of ...

      Read Full Article
    14. Massachusetts General Hospital Receives NIH Grant for OCTOLOGY: Histology Using Optical Coherence Tomography

      Massachusetts General Hospital Receives NIH Grant for OCTOLOGY: Histology Using Optical Coherence Tomography

      Massachusetts General Hospital Receives a 2015 NIH Grant for $217,500 for OCTOLOGY: Histology Using Optical Coherence Tomography. The principal investigator is Bruce Fischl. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. While histology remains the gold standard for assessing human neuroanatomy, the procedures for sectioning and hand mounting tissue for microscopic imaging are not substantially different than they were 100 years ago. These steps introduce irremediable distortions into the tissue sections making it difficult or impossible to align sections with suffiient accuracy to create 3D histological volumes at the micron ...

      Read Full Article
    15. University of Maryland Receives NIH Grant for Identification of AF Ablation Targets via a Steerable Actuated Catheter

      University of Maryland Receives NIH Grant for Identification of AF Ablation Targets via a Steerable Actuated Catheter

      University of Maryland Receives a 2015 NIH Grant for $222,800 for Identification of AF Ablation Targets via a Steerable Actuated Catheter. The principal investigator is Jaydev Desai. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. Atrial fibrillation (AF) is the most common cardiac arrhythmia and has high patient morbidity, increases mortality two-fold, and increases health care costs. Each year, about 200,000 Americans are newly diagnosed with AF with a prevalence of several million in the U.S. alone. In the majority of cases, AF has been shown to originate ...

      Read Full Article
    16. Columbia University Receives NIH Grant for Structural and Functional Progression of Glaucomatous Damage to the Macula

      Columbia University Receives NIH Grant for Structural and Functional Progression of Glaucomatous Damage to the Macula

      Columbia University Receives 2015 NIH Grant for $400,000 for Structural and Functional Progression of Glaucomatous Damage to the Macula. The principal investigator is Carlos Gustavo De Moraes. The program began in 20125 and ends in 2018. Below is a summary of the propose work. There is compelling evidence that glaucomatous damage to the macula occurs even in early stages of the disease. The macula comprises about 30% of all retinal ganglion cells and its information corresponds to over 50% of the visual cortex. However, glaucomatous damage to the macula is often missed in clinical practice. Some of the reasons ...

      Read Full Article
    17. University of California Irvine Receives NIH Grant for Phase Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      University of California Irvine Receives NIH Grant for Phase Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      University of California Irvine Receives a 2015 NIH Grant for $664,990 for Phase Resolved ARF Optical Coherence Elastography for Intravascular Imaging. The principal investigator is Zhongping Chan The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography (OCT), ultrasound (US), and phase-resolved acoustic radiation force optical coherence elastography (ARF-OCE). The multimodal intravascular imaging system is unique in that it combines the advantages of the high spatial resolution of ...

      Read Full Article
    18. Massachusetts General Hospital Receives NIH Grant for High Resolution Optical Imaging

      Massachusetts General Hospital Receives NIH Grant for High Resolution Optical Imaging

      Massachusetts General Hospital Receives a 2015 NIH Grant for $285,859 for High Resolution Optical Imaging. The principal investigator is David Boas. The program began in 2015 and ends in 2015. Below is a summary of the proposed work.

      This core will support the theme of functional coupling between glial, endothelial, and neuronal cells by using both in vivo and in vitro novel optical imaging to dissect the mechanisms of brain plasticity after cerebral ischemia . Novel optical imaging technologies have unique capability to measure the dynamics of glia, endothelium, and neurons as well as hemodynamic, metabolic, and electrophysiologic responses upon ...

      Read Full Article
    19. UC Irvine Receives NIH Grant for Low-Cost Simple Oral cancer Screening Device for Low-Resource Settings.

      UC Irvine Receives NIH Grant  for Low-Cost Simple Oral cancer Screening Device for Low-Resource Settings.

      University of California Irvine Receives a 2015 NIH Grant for $25,263 for Low-Cost Simple Oral cancer Screening Device for Low-Resource Settings. The principal investigator is Petra Wilder-Smith. The program began in 2012 and ends in 2015. Below is a summary of the proposed work. Our long-term goal is to develop an inexpensive, simple, portable means of screening for oral cancer in the field by basic level healthcare workers in low-resource environments. Screening will identify whether a person needs to travel to a center with higher levels of expertise in oral cancer for further tests and potential cancer therapy. The ...

      Read Full Article
    20. Boston University Receives NIH Grant for Visualizing Cortical Microstructures by Optical Coherence Tomography

      Boston University Receives NIH Grant for Visualizing Cortical Microstructures by Optical Coherence Tomography

      Boston University Receives a 2015 NIH Grant for $259,490 for Visualizing Cortical Microstructures by Optical Coherence Tomography. The principal investigator is Katehleen Rockland. The program began in 2015 and ends in 2017. Below is a summary of the propose work.

      Area-specific differences in microstructure and cell-type distribution are well-established across cortical regions in the human brain; and specific morphological changes have been identified in different disease conditions, such as cortical thinning or, at a finer level of resolution, changes in specific pyramidal or non-pyramidal cell populations. These data, however, are based on relatively small sample sizes and can be ...

      Read Full Article
    21. University of Texas, Austin Receives NIH Grant for Optical Imaging of Baseline Blood Flow and Oxygenation During Stroke

      University of Texas, Austin Receives NIH Grant for Optical Imaging of Baseline Blood Flow and Oxygenation During Stroke

      University of Texas, Austin Receives a 2015 NIH Grant for $465,127 for Optcial Imaging of Baseline Blood Flow and Oxygenation During Stroke. The principal investigator is Andrew Dunn. The program began in 2010 and ends in 2019. Below is a summary of the proposed work. Quantitative imaging of cerebral blood flow is essential in preclinical stroke studies for monitoring the efficacy of potential treatments and for understanding the role of vascular reorganization in functional recovery. Similarly, real-time imaging of blood flow is crucial during neurovascular surgery in humans, where intraoperative visualization of vascular patency and tissue perfusion are needed ...

      Read Full Article
    22. National Research Council of Canada Receives NIH Grant for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization

      National Research Council of Canada Receives NIH Grant for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization

      National Research Council of Canada Receives NIH Grant for $208,382 for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization. The principal investigator is Michale Sowa. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Dental caries continues to be prevalent in children and youth, with significant oral health disparities existing in some population groups. This disease arises when the balance between pathological factors (e.g. cariogenic bacteria) and protective factors (e.g. saliva flow) is tipped in favour of demineralization. The prevalence of caries suggests that the disease ...

      Read Full Article
    23. Stanford University Receives a NIH Grant for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo

      Stanford University Receives a  NIH Grant for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo

      Stanford University Receives a 2015 NIH Grant for $448,758 for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo. The principal investigator is John Oghalai. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. The function of the cochlea is to transduce complex sound pressure waves into electrical signals. Organ of Corti vibration is based upon a complex interplay between passive mechanical structures and active OHC- based processes. While laser Doppler vibrometry has added tremendously to our understanding of cochlear physiology, this technique is limited. Only motion from one ...

      Read Full Article
    24. Georgetown University Receives NIH Grant for Non-Invasive Evaluation of Transplant Kidney using OCT

      Georgetown University Receives NIH Grant  for Non-Invasive Evaluation of Transplant Kidney using OCT

      Georgetown University Receives a 2015 NIH Grant for $388,865 for Non-Invasive Evaluation of Transplant Kidney using OCT. The principal investigator is Peter Andrews. The program began in 2014 and ends in 2016. Below is a summary of the proposed work. There is currently a worldwide shortage of kidneys for transplantation due mainly to the fact that there is no reliable means to determine their viability (i.e., kidneys stored for long periods of time, etc.). Also, following transplantation, kidneys oftn do not function immediately and their status is unclear. Previously, we have shown that the histopathology of living, superficial ...

      Read Full Article
    1-24 of 452 1 2 3 4 ... 17 18 19 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (2 articles) Harvard University
    2. (2 articles) Massachusetts General Hospital
    3. (1 articles) Stanford University
    4. (1 articles) Johns Hopkins University
    5. (1 articles) University of Illinois at Urbana-Champaign
    6. (1 articles) University of Michigan
    7. (1 articles) Case Western Reserve University
  4. People in the News

    1. (1 articles) Guillermo J. Tearney
    2. (1 articles) Andrew M. Rollins
    3. (1 articles) Stephen A. Boppart