1. Articles in category: Funding

    1-24 of 575 1 2 3 4 ... 22 23 24 »
    1. Imaging apparatus for diagnosis, information processing apparatus, control method thereof, program and computer-readable storage medium

      Imaging apparatus for diagnosis, information processing apparatus, control method thereof, program and computer-readable storage medium

      An imaging apparatus for diagnosis and a control method of an imaging apparatus for diagnosis are disclosed, which acquire line data represented by multiple luminance values in a radial direction from a rotation center position of an imaging core, which are derived by a rotation position and movement of the imaging core. Then, based on the acquired line data, an image of a two-dimensional space in which .theta. representing a rotation angle and z representing a position in a movement direction are set to two axes is generated and displayed.

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    2. LX Medical Corporation Receives NIH Grant for Biopsy Probes with Real-Time Multi-Modality Image Guidance for Peripheral Lung Nodules

      LX Medical Corporation Receives  NIH Grant for Biopsy Probes with Real-Time Multi-Modality Image Guidance for Peripheral Lung Nodules

      LX Medical Corporation Receives a 2017 NIH Grant for Biopsy Probes with Real-Time Multi-Modality Image Guidance for Peripheral Lung Nodules. The principal investigator is Andrei Vertikov. Below is a summary of the proposed work. Recent technological advances have enabled low-dose spiral CT to become an effective tool for lung cancer screening. The majority of pulmonary nodules detected on CT, however, are small and difficult to diagnose. While CT-guided transthoracic needle biopsy (CT-TTNB) has high diagnostic accuracy (70% to 90% depending on nodule size), the risk of complications such as pneumothorax and bleeding is high. Diagnostic confirmation by transbronchial lung biopsy ...

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    3. Stanford faculty named in first cohort of Chan Zuckerberg Biohub investigators

      Stanford faculty named in first cohort of Chan Zuckerberg Biohub investigators

      The Chan Zuckerberg Biohub committed more than $50 million to support 47 of the best investigators from Bay Area universities, including 19 from Stanford University. The investigators each receive five-year appointments worth up to $1.5 million to carry out non-conventional scientific exploration and to invent new tools to accelerate the pace of discovery. De la Zerda’s goal is to image 100 million cells in living tissues at single-cell resolution by using optical coherence tomography. One of the potential uses of his technique will be to visualize cancer markers to delineate the margins of tumors.

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    4. Voxeleron LLC Receives a 2017 NIH Grant for $222,991 for Retinal Image Analysis Software for Neurodegenerative Disease Research

      Voxeleron LLC Receives a 2017 NIH Grant for $222,991 for Retinal Image Analysis Software for Neurodegenerative Disease Research

      Voxeleron LLC Receives a 2017 NIH Grant for $222,991 for Retinal Image Analysis Software for Neurodegenerative Disease Research. The principal investigator is Daniel Russakoff. Below is a summary of the proposed work. Our goal is to develop and validate a device-independent software application for analysis of optical coherence tomography (OCT) images of the human retina. Our system will make quantitative measurements of retinal layer thicknesses at the macula in support of the generation of biomarkers for measuring onset and progression of ocular and neurodegenerative diseases, including age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma, multiple sclerosis (MS), Alzheimer’s ...

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    5. Northwestern University Receives a NIH Grant for A Clinically Applicable Model Of Retinal Oxygen Metabolism

      Northwestern University Receives a NIH Grant for A Clinically Applicable Model Of Retinal Oxygen Metabolism

      Northwestern University Receives at 2017 NIH Grant for $195,625 for A Clinically Applicable Model Of Retinal Oxygen Metabolism. The principal investigator is Robert Linsenmeier. The program began in 2017 and ends in 2019. Below is a summary of the proposed work. This proposal seeks to establish a correlation between the metabolism of the inner retina and the oxygen supply from the inner retinal vascular network measured by optical coherence tomography. This work will be done in rats, but will have immediate clinical application. Several important diseases cause damage to the inner retina, including diabetes, glaucoma, and vascular occlusion. Considerable ...

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    6. University of California at Irvine Receives a 2017 NIH for $14,260 Grant for Onco-Imaging and Biotechnology Program

      University of California at Irvine Receives a 2017 NIH for $14,260 Grant for Onco-Imaging and Biotechnology Program

      University of California at Irvine Receives a 2017 NIH for $14,260 Grant for Onco-Imaging and Biotechnology Program. The principal investor Christopher Hughes. Below is a summary of the proposed work. Onco-Imaging and Biotechnology (OIB) The broad goal of the OIB Program is to develop and assess quantitative systems and technologies that improve detection, clinical management, and quality of life for cancer patients. OIB is strongly interdisciplinary, integrating basic scientists with technologists and clinicians and is focused around 3 key themes. Critically, each of the themes includes basic science, technology development, and translational research activities spanning from animal models to ...

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    7. State University of New York at Stony Brook Receives NIH Grant for Calcium-Related Neurotoxity of Cocaine

      State University of New York at Stony Brook Receives NIH Grant for Calcium-Related Neurotoxity of Cocaine

      State University of New York at Stony Brook Receives a 2017 NIH Grant for $344,250 for Calcium-Related Neurotoxity of Cocaine. The principal investigator is Congwu Du. The program began in 2012 and ends in 2018. Below is a summary of the proposed work. Cocaine-induced stroke and hemorrhage in the brain are among the most serious medical complications. The mechanisms underlying these effects are poorly understood but are likely to reflect in part its vasoactive effects that may be exacerbated with repeated drug exposures. Our poor understanding of the cerebrovascular effects of cocaine are due in part to technological limitations ...

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    8. Emanuel Hospital and Health Center Receives NIH Grant for Optic Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital and Health Center Receives NIH Grant  for Optic Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital and Health Center Receives a 2017 NIH Grant for $507,846 for Optic Nerve Head SD-OCT Imaging in Glaucoma. The principal investigator is Claude Burgoyne. The program began in 2010 and ends in 2019. Below is a summary of the proposed work. As a result of discoveries made during the first project period, we propose a paradigm change for clinical assessment of the Optic Nerve Head (ONH), peripapillary retinal nerve fiber layer (RNFL) and macula based on acquisition and regionalization of Spectral Domain Optical Coherence Tomography (SDOCT) ONH, RNFL and macula datasets relative to the axis between the ...

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    9. University of Alabama Receives NIH Grant for The Mechanisms Underlying Abnormal Mucus and Its Clearance in The Cystic Fibrosis Rat.

      University of Alabama Receives NIH Grant for The Mechanisms Underlying Abnormal Mucus and Its Clearance in The Cystic Fibrosis Rat.

      University of Alabama at Birmingham Receives a 2017 NIH Grant for $117,056 for The Mechanisms Underlying Abnormal Mucus and Its Clearance in The Cystic Fibrosis Rat. The principal investigator is Susan Birket. The program began in 2017 and ends in 2022. Below is a summary of the propose work. Abnormal mucociliary clearance (MCC) is a critical component of cystic fibrosis (CF) lung disease, especially in the presence of infection; however, the mechanisms responsible for the defect are not well understood. Until recently, evaluation of this question has been primarily limited to cell culture models which do not replicate the ...

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    10. University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease

      University of Alabam Receives NIH Grant for In Vivo Ultrastruture of Chorioretinal Disease

      University of Alabam at Birmingham Receives a 2017 NIH Grant for $330,750 for In Vivo Ultrastruture of Chorioretinal Disease. The principal investigator is Yuhua Zhang. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. Age-related macular degeneration (AMD) is a leading cause of vision loss in more than 10 million older Americans. For decades, AMD has been characterized by accumulation of extracellular lesions called drusen on the inner surface of Bruch's membrane (BrM), posterior to the retinal pigment epithelium (RPE), in a compartment called the sub-RPE space. Drusen are now ...

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    11. Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Isreal Deaconess Medical Center Receives a 2017 NIH Grant for $164,376 for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology. The principal investigator is Eric Osborn. The program began in 2017 and ends in 2020. Below is a summary of the propose work. Dr. Eric Osborn is an early career faculty member at Beth Israel Deaconess Medical Center (BIDMC) and Massachusetts General Hospital (MGH), and an Instructor in Medicine at Harvard Medical School, Boston, Massachusetts. He is a graduate of the MD-PhD program at Harvard Medical School and Massachusetts Institute of Technology, and has completed clinical training in medicine ...

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    12. The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      The University of Houston Receives a 2017 NIH Grant for $311,241 for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development. The principal investigator is Kirll Larin. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The overall objective of this study is to develop an optical coherence tomography (OCT) based high- resolution mouse embryonic brain imaging and analysis approach, and to use this method in correlation with molecular analysis to understand the interplay between ethanol (EtOH) and nicotine (NIC) effects on embryonic brain development. Maternal exposures ...

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    13. UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      UCDavis Receives NIH Grant for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT

      The University of California at Davis Receives a 2017 NIH Grant for $97,834 for Properties of Photoreceptoers and Muller Cells Investigated with AO-OCT. The principal investigator is Ravi Jonnal. The program began in 2016 and ends in 2017. Below is a summary of the proposed work. The research proposed for this award will examine functional and structural properties of single cells in the human retina. The three Aims will link the candidate's scientific background and career plans to study the human retina using a combination of adaptive optics (AO) and optical coherence tomography (OCT) which provide high lateral ...

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    14. University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography.

      University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography.

      University of Miami Receives a 2017 NIH Grant for $227,722 for Endothelium/Descemet's Membrane Complex Optical Tomography. The principal investigator is Mohamed Shousha. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. More than 50% of corneal transplants, the most common form of solid organ transplantation, are performed to restore vision lost secondary to corneal endothelial failure. More than 25% of those transplants will eventually fail and endothelial cell rejection leading to failure is the single most important cause. The key to protec the endothelium is the early and accurate ...

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    15. Duke University Receives NIH Grant for Advanced A/LCI Systems for Improved Clinical Utility.

      Duke University Receives NIH Grant  for Advanced A/LCI Systems for Improved Clinical Utility.

      Duke University Receives a 2017 NIH Grant for $501,101 for Advanced A/LCI Systems for IMproved linical Utility. The principal investigator is Adam Wax. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. There is a critical unmet need for in vivo detection of dysplasia in patients with Barrett's esophagus (BE), a neoplastic tissue state resulting from chronic acid reflux. BE is associated with an increased risk of esophageal cancer, a disease with a high morbidity rate. Patients with BE undergo periodic endoscopic surveillance with systematic biopsy to search for ...

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    16. UIUC Receives a NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins

      UIUC Receives a NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins

      University of Illinois at Urbana-Champaign Receives a 2017 NIH Grant for $548,714 for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins. The principal investigator is Stephan Boppart. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. Breast cancer is a global healthcare burden, not only for the patients diagnosed with this disease, but also their families and friends. The surgical treatment of breast cancer, while successful, has significant limitations that increase patient anxiety, increase costs, and can increase the risk for local recurrence and lifelong post-operative complications. A primary limitation stems ...

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    17. 'Galahad' project to develop OCT for glaucoma diagnosis

      'Galahad' project to develop OCT for glaucoma diagnosis

      Multiple UK and Danish partners involved in €4M effort to develop high-res system based around supercontinuum source . Glaucoma: high-res imaging needed for diagnosis Gooch & Housego and NKT Photonics are among eight partners from the UK and Denmark who have just started work on a new €4 million European project to develop a high-resolution optical coherence tomography (OCT) system for glaucoma diagnosis. The “GALAHAD” (short for Glaucoma - Advanced, Label-free High Resolution Automated OCT Diagnosis) effort, funded through the European Commission’s Horizon 2020 innovation platform, officially kicked off this month and runs for three years. High-res requirements Current OCT systems offer ...

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    18. Wavelength tunable light source

      Wavelength tunable light source

      To provide a wavelength tunable light source which can both ensure operation speed and reduce a drive voltage. A wavelength tunable light source according to the present invention includes a pair of reflectors at least one of which is a movable reflector, an active layer provided between the pair of reflectors, and a beam on part of which the movable reflector is formed and which is supported by a support member. The beam includes a blade part projecting between the support member and the movable reflector in a direction intersecting a stretching direction of the beam, and a center of ...

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    19. Google researchers use deep learning to detect diabetic retinopathy with upwards of 90 percent accuracy

      Google researchers use deep learning to detect diabetic retinopathy with upwards of 90 percent accuracy

      A team of Google researchers has published a paper in the Journal of the American Medical Association showing that Google's deep learning algorithm, trained on a large data set of fundus images, can detect diabetic retinopathy with better than 90 percent accuracy. "These results demonstrate that deep neural networks can be trained, using large data sets and without having to specify lesion-based features, to identify diabetic retinopathy or diabetic macular edema in retinal fundus images with high sensitivity and high specificity," researchers write in the paper . "This automated system for the detection of diabetic retinopathy offers several advantages, including ...

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    20. #1 – OCT as a Diagnostic Tool

      #1 – OCT as a Diagnostic Tool

      In 1991, David Huang, MD, PhD, of the Massachusetts Institute of Technology described the first use of optical coherence tomography (OCT) for noninvasive cross-sectional imaging in biological systems. When the first commercial time-domain OCT (TD-OCT) debuted 5 years later, it was able to acquire data at a rate of only 100 axial scans per second. Six years later, this speed had quadrupled to 400 axial scans per second. As improvements in speed and quality persisted, OCT became the gold standard for diagnosis of glaucoma and many retinal diseases such as age-related macular degeneration and diabetic eye disease. OCT is based ...

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    21. New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives a 2016 NIH Grant for $714,891 for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. The program began in 2016 and ends in 2019. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness and visual morbidity. Because the disease causes irreversible damage to neural tissue it is of upmost importance to identify glaucoma and its progression at the earliest possible stages. Through advancements in the use of optical coherence tomography (OCT) and other technologies, the long-term goal of this research project ...

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    22. Celloptic Incorporated Receives NIH Grant for A New Holographic 3D Camera for Fundus Imaging

      Celloptic Incorporated Receives NIH Grant for A New Holographic 3D Camera for Fundus Imaging

      Celloptic Incorporated Receives a 2016 NIH Grant for $225,635 for A New Holographic 3D Camera for Fundus Imaging. The principal investigator is Gary Brooker. The program began in 2016 and ends in 2017. Below is a summary of the proposed work. A NEW HOLOGRAPHIC 3D CAMERA FOR FUNDUS IMAGING Abstract In the United States, retinal disease is the most common cause of visual impairment, with age-related macular degeneration (AMD) and diabetic retinopathy (DR) being the most common retinal diseases. For each of the above conditions, high resolution and three-dimensional (3D) imaging of the retina, retinal vasculature, choroid and/or ...

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    23. The University of Colorado at Denver Receives NIH Grant for Photonics Monitoring and Modeling Core

      The University of Colorado at Denver Receives NIH Grant for Photonics Monitoring and Modeling Core

      The University of Colorado at Denver Received at 2016 NIH Grant for $691,303 for Photonics Monitoring and Modeling Core. The principal investigator is Matthew Brenner. The program beghan in 2016 and ends in 2017. Below is a summary of the proposed work. The Photonics Monitoring and Modeling Core (PMMC) consists of three core photonics based novel diagnostic technologies and a highly monitored mid-size animal model (rabbit) testing facility based at the University of California, Irvine, Beckman Laser Institute that support investigations at UC Irvine, UC San Diego, and the University of Colorado. The Core will provide all investigators with ...

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    24. Laser thermal therapy monitoring using complex differential variance in optical coherence tomography

      Laser thermal therapy monitoring using complex differential variance in optical coherence tomography

      Conventional thermal therapy monitoring techniques based on temperature are often invasive, limited by point sampling, and are indirect measures of tissue injury, while techniques such as magnetic resonance and ultrasound thermometry are limited by their spatial resolution. The visualization of the thermal coagulation zone at high spatial resolution is particularly critical to the precise delivery of thermal energy to epithelial lesions. In this work, an integrated thulium laser thermal therapy monitoring system was developed based on complex differential variance (CDV), which enables the 2D visualization of the dynamics of the thermal coagulation process at high spatial and temporal resolution with ...

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