1. Articles in category: Funding

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    1. A group of 28 students affiliated with the University of Arizona has received the prestigious National Science Foundation Graduate Research Fellowship.

      A group of 28 students affiliated with the University of Arizona has received the prestigious National Science Foundation Graduate Research Fellowship.

      David Vega , a doctoral student finishing his first year in the optical sciences program. Vega's research is based on early detection of ovarian cancer using optical coherence tomography and multiphoton microscopy. The breakthrough technologies he is developing are transferable to numerous applications and offer broad impacts in several other fields, ranging from other medical diagnostics to astronomy

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    2. Piccolo project develops endoscope for colon cancer diagnosis

      Piccolo project develops endoscope for colon cancer diagnosis

      New instrument from Horizon 2020 project will use OCT and MPT for high-resolution imaging. Piccolo project: the European consortium A project funded under the EU Horizon 2020 program aims to develop a novel endoscope for the identification and diagnosis of colorectal cancer, the latest step in the use of optical technologies to tackle one of the world's predominant cancers. Running for three years until December 2019, and involving nine European industrial and research partners led by Spain's Tecnalia Research & Innovation research center, the Piccolo project envisages an advanced endoscope instrument able to deliver high-resolution structural and functional imaging ...

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    3. USC ReceivesNIH Grant for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans

      USC ReceivesNIH Grant for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans

      University of Southern California Receives a 2017 NIH Grant for $223,560 for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans. The principal investigator is Grace Richter. The program began in 2017 and ends in 2022. Below is a summary of the proposed work. This K23 application is submitted by Grace Richter, MD, MPH, an Assistant Professor of Ophthalmology in the Glaucoma Division at the USC Roski Eye Institute at Keck School of Medicine of University of Southern California. The primary objectives of this K23 career development proposal are: 1) to ...

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    4. University of Miami Receives NIH Grant for Reversible Dysfunction of Retinal Ganglion Cells in Glaucoma

      University of Miami Receives NIH Grant for Reversible Dysfunction of Retinal Ganglion Cells in Glaucoma

      The University of Miami Receives a 2017 NIH Grant for $310,837 for Reversible Dysfunction of Retinal Ganglion Cells in Glaucoma. The principal investigator is Vittorio Porciatti. The program began in 2003 and ends in 2018. Below is a summary of the proposed work. Glaucoma causes progressive damage and death of retinal ganglion cells (RGCs) resulting in blindness. The prevalence of the disease will rise to a projected 3 million Americans by 2020. Our long-term goal is to prevent RGC death in the early stages of glaucoma and preserve vision. The objective of this study is to identify dysfunctional RGCs ...

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    5. Stanford University Receives NIH Grant for Cochlear Mechanics in the Mouse

      Stanford University Receives NIH Grant for Cochlear Mechanics in the Mouse

      Stanford University Receives a 2017 NIH Grant for $307,982 for Cochlear Mechanics in the Mouse. The principal investigator is John Oghalai. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. Sound pressure produces force across the mammalian cochlear partition, ultimately creating a vibratory traveling wave that propagates longitudinally up the cochlear duct. The key feature distinguishing this process from the non-mammalian cochlea is amplification, whereby forces produced by thousands of outer hair cells (OHCs) sharpen and amplify the traveling wave. Our overarching objective is to understand how the complex biomechanics of ...

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    6. Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients

      Massachusetts General Hospital Receives NIH Grant for Intracoronary Imaging of Plaque Collagen in Patients

      Massachusetts General Hospital Receives a 2017 NIH Grant for $865,789 for Intracoronary Imaging of Plaque Collagen in Patients. The principal investigator is Seemantini Nadkarni. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The goal of this proposal is to develop and validate an intracoronary imaging device for the assessment of plaque collagen content and architecture in patients. Acute myocardial infarction (AMI), caused by the rupture of unstable plaque, is the leading cause of death worldwide. Collagen and vascular smooth muscle cells (vSMCs) together impart mechanical stability to a plaque, and ...

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    7. Physical Sciences ReceivesNIH Grant for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes

      Physical Sciences ReceivesNIH Grant  for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes

      Physical Sciences Incorporated Receives a 2017 NIH Grant for $230,823 for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes. The principal investigator is Mircea Mujat. The program began in 2017 and ends in 2018. Below is a summary of the proposed work. There is currently a significant need for new non-invasive imaging techniques able to accurately quantify biomarkers for early detection, diagnosis, and quantification of complications in type 1 diabetes (T1D) such as diabetic retinopathy (DR). Physical Sciences Inc. (PSI) proposes to develop an imaging platform based on a new detection arrangement retrofitted to ...

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    8. University of Houston Receives NIH Grant f for Optical Coherence Elastography of the Cornea

      University of Houston Receives NIH Grant f for Optical Coherence Elastography of the Cornea

      University of Houston Receives a 2017 NIH Grant for $362,939 for Optical Coherence Elastography of the Cornea. The principal investigator is Kirill Larin. The program began in 2012 and ends in 2020. Below is a summary of the proposed work. Optical Coherence Elastography of the Cornea The fundamental physical properties of the outer tunic of the eye determine the structural characteristics of the ocular globe and may be altered in several devastating disease states including axial elongation in myopia, pathological deformation in keratoconus, and iatrogenic keratoectasia following corneal refractive surgery. These biomechanical tissue characteristics not only influence our clinical ...

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    9. The University of Wisconsin-Madison Receives Grant for Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases

      The University of Wisconsin-Madison Receives  Grant for  Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases

      The University of Wisconsin-Madison Receives a 2017 NIH Grant for $768,348 for Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases. The principal investigator is Ronald Klein. The program began in 1987 and ends in 2019. Below is a summary of the proposed work. This proposal builds on a longitudinal cohort study of persons participating in the Beaver Dam Eye Study (BDES), funded by National Eye Institute grant U10 EY006594. The study included persons aged 43-86 years living in the city and township of Beaver Dam, Wisconsin who were identified in a private census in 1987-88 and were examined ...

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    10. University of Wisconsin-Madison Receives NIH Grant for Epidemiology of Age-Related Macular Degeneration and Other retinal diseases -Enrollment Center

      University of Wisconsin-Madison Receives NIH Grant  for Epidemiology of Age-Related Macular Degeneration and Other retinal diseases -Enrollment Center

      University of Wisconsin-Madison Receives a 2017 NIH Grant for $149,848 for Epidemiology of Age-Related Macular Degeneration and Other retinal diseases -Enrollment Center. The principal investigator is Barbara Klein. The program began in 2017 and ends in 2018. Below is a summary of the proposed work. Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases Project Summary/Abstract This proposal builds on a longitudinal cohort study of persons participating in the Beaver Dam Eye Study (BDES), funded by National Eye Institute grant U10 EY006594. The study included persons aged 43-86 years living in the city and township of Beaver Dam ...

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    11. OHSU Receives NIH Grant f for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

      OHSU Receives NIH Grant f for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

      Oregon Health & Science University Receives a 2017 NIH Grant for $487,587 for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy. The principal investigator is Yali Jia. The program began in 2017 and ends in 2021. Below is a summary of the proposed work. Our group has demonstrated that optical coherence tomography angiography (OCTA) can address many of the disadvantages of fluorescein angiography (FA) in diabetic retinopathy (DR). OCTA uses the intrinsic contrast of blood cell motion and therefore does not require dye injection, making it entirely non-invasive and suitable for routine examination. OCTA is three-dimensional and can ...

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    12. University of Iowa Receives NIH Grant for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema

      University of Iowa Receives NIH Grant for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema

      University of Iowa Receives a 2017 NIH Grant for $305,775 for 3D Image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema. The principal investigator is Mona Garvin. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Currently, the clinical assessment of optic nerve swelling is limited by the subjective ophthalmoscopic evaluation by experts in order to diagnose and differentiate the cause of the optic disc edema. The long-term goal of our research effort is to develop automated 3D image-analysis approaches for the identification of an optimal set of ...

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    13. Massachusetts Institute of Technology Receives NIH Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Receives  NIH Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Receives a 2017 NIH Grant for $259,717 for Optical Biopsy Using Optical Coherence Tomography. The principal investigator is James Fujimoto. The program began in 1997 and ends in 2019. Below is a summary of the proposed work. This is a multidisciplinary collaboration between investigators at the Massachusetts Institute of Technology and the VA Boston Healthcare System integrating imaging technology research, clinical imaging studies, medical device development and animal imaging studies. Esophageal cancer is a lethal malignancy, with a five-year survival rate of 16%. Barrett's esophagus (BE) and dysplasia are precursors to esophageal adenocarcinoma (EAC ...

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    14. Icahn School of Medicine at Mount Siani Receives NIH Grant for Age-Related Changes in Human Retinal Microvascular.

      Icahn School of Medicine at Mount Siani Receives NIH Grant for Age-Related Changes in Human Retinal Microvascular.

      Icahn School of Medicine at Mount Siani Receives a 2017 NIH Grant for $417,722 for Age-Related Changes in Human Retinal Microvascular. The principal investigator is Yuen Ping Toco Chui. The program began in 2017 and ends in 2022. Below is a summary of the proposed work. Age-related degeneration of the retinal vasculature is one of the most pervasive developments in the aging eye, resulting in increased susceptibility to vision threatening ocular diseases. Diabetic retinopathy in many ways manifests as accelerated aging. Despite extensive research, quantitative data describing the dynamic changes that occur during normal aging of the human retinal ...

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    15. UC Irving Receives NIH Grant for Phase Resolved ARF Optical Coherence Elastrography for Intravascular Imaging

      UC Irving Receives NIH Grant for Phase Resolved ARF Optical Coherence Elastrography for Intravascular Imaging

      University of California at Irving Receives a 2017 NIH Grant for $659,953 for Phase Resolved ARF Optical Coherence Elastrography for Intravascular Imaging. The principal investigator is Zhongping Chen. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography (OCT), ultrasound (US), and phase-resolved acoustic radiation force optical coherence elastography (ARF-OCE). The multimodal intravascular imaging system is unique in that it combines the advantages of the high spatial resolution ...

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    16. £100k awarded in new CRACK IT Solutions funding

      £100k awarded in new CRACK IT Solutions funding

      Two innovative projects have been awarded £50k each through the NC3Rs CRACK IT Solutions technology partnering programme. CRACK IT Solutions supports collaborations to help further develop and validate novel technologies with potential 3Rs benefits. Applying novel imaging platforms to tissue engineered corneal tissue constructs Professor Zhihong Huang and colleagues at the University of Dundee have developed functional optical coherence tomography (OCT) to enable high quality, ultrafast, qualitative and quantitative characterisation of both tissue structure and function in vivo . The technique has the potential to both reduce and refine animal use, as long-term non-invasive serial tissue monitoring in small animals is ...

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    17. Damae Medical Raises €2M in Funding

      Damae Medical Raises €2M in Funding

      Damae Medical , a Paris, France-based medtech company, closed a €2m funding. Backers included Kurma Partners, Idinvest Partners, News Invest, Paris-Saclay Seed Fund co-managed by Partech Ventures, and private investors. The company intends to use the funds to finance the development and CE marking of OCTAV®, which is scheduled for mid-2018. Founded in September 2014 by Anaïs Barut, CEO, Damae Medical aims to provide dermatologists with a novel, in vivo imaging technology for a deep look into the skin. This technology enables cellular-resolution imaging of the skin similar to histology, without the need for tissue excision and processing. The company ...

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    18. University of Illinois at Chicago Receives NIH Grant for Functional Imaging of Retinal Photoreceptors

      University of Illinois at Chicago Receives NIH Grant  for Functional Imaging of Retinal Photoreceptors

      The University of Illinois at Chicago Received at 2017 NIH Grant for $299,044 for Functional Imaging of Retinal Photoreceptoers. The principal investigator is Zincheng Yao. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. Many eye diseases, such as age-related macular degeneration (AMD), diabetic retinopathy (DR) and glaucoma, involve pathological changes in retinal photoreceptors and/or inner retinal neurons. It is well known that different diseases can target different cell types. In principle, physiological modification must occur in diseased cells, before detectable abnormality of retinal morphology. Therefore, functional evaluation of retinal ...

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    19. UC Irvine Receives at NIH for Combined OCT/US/PAT System for Intravascular Imaging

      UC Irvine Receives at  NIH for Combined OCT/US/PAT System for Intravascular Imaging

      University of California at Irvine Received at 2017 NIH Grant for $686,184 for Combined OCT/US/PAT System for Intravascular Imaging. The principal investigator is Zhongping Chen. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. Atherosclerosis is a progressive disease that is characterized by the accumulation of lipids, cholesterol, fibrous constituents, monocytes, and various other inflammatory cells in the arterial wall. Atherosclerosis is one of the major causes of morbidity and mortality in developed countries. The major cause of deaths from heart attacks (86%) and brain aneurysm (45%) are due ...

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    20. Columbia University Receives NIH Grant for Ultrasound Perfusion Imaging in Glaucoma

      Columbia University Receives NIH Grant for Ultrasound Perfusion Imaging in Glaucoma

      Columbia University Receives a 2017 NIH Grant for $411,119 for Ultrasound Perfusion Imaging in Glaucoma. The principal investigator is Ronald Silverman. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. Glaucoma is an optic neuropathy and the leading cause of blindness, affecting over 3 million people in the United States. Elevated intraocular pressure (IOP) is a well-known risk factor for this disease, but reduced ocular perfusion is also now appreciated to be an important risk factor in primary open-angle glaucoma (POAG), the most common form of glaucoma. While optical methods such ...

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    21. USC Receives NIH Grant for 3D OCT Angiography for Quantitative Characterization of Diabetic Retinopathy

      USC Receives NIH Grant for 3D OCT Angiography for Quantitative Characterization of Diabetic Retinopathy

      University of Southern California Receives a 2017 NIH Grant for $206,250 for 3D OCT Angiography for Quantitative Characterization of Diabetic Retinopathy. The principal investigator is Youngang Shi. The program began in 2017 and ends in 2019. Below is a summary of the proposed work. In the clinical diagnosis of diabetic retinopathy (DR), fluorescein angiography (FA) is currently the only method used routinely for the detection and treatment of ischemia, but it is an invasive method and not sensitive to early microvascular changes before the onset of visual symptoms. For the early detection and management of ischemia in DR, Optical ...

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    22. University of Washington Received NIH Grant Optical Coherence Elastography of Corneal Dynamics

      University of Washington Received NIH Grant Optical Coherence Elastography of Corneal Dynamics

      The University of Washington Received a 2017 NIH Grant for $529,475 Optical Coherence Elastography of Corneal Dynamics. The principal investigator is Tueng Shen. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. The cornea is a highly organized, layered (lamellae) structure of collagen fibrils providing both high tensile strength to protect the eye and 70% of it refractive power. Although physical properties are closely linked to its primary optical function, its response to surgical interventions, and the results of routine eye tests such as intraocular pressure measurements, corneal biomechanics has not ...

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    23. Pennsylvania State University Receives NIH Grant for Score2 Comparative Trial (SCT)

      Pennsylvania State University Receives NIH Grant for Score2 Comparative Trial (SCT)

      Pennsylvania State University Received a 2017 NIH Grant for $769,262 for Score2 Comparative Trial (SCT). The principal investigator is Ingrid Scott. The program began in 2013 and ends in 2019. Below is a summary of the proposed work. This comparative effectiveness research proposal aims to support a multicenter, prospective, randomized, NIH-defined phase III clinical trial to compare treatment protocols for decreased vision due to macular edema secondary to central retinal vein occlusion (CRVO) based on results of recent randomized trials. This application is an investigator-initiated project in response to Program Anouncement Number PAR-10-207. The trial is designed to assess ...

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    24. OHSU Receives NIH Grant for Dynamic Changes in the Chick Developing Heart in Response to Altered Hemodynamics

      OHSU Receives NIH Grant for Dynamic Changes in the Chick Developing Heart in Response to Altered Hemodynamics

      Oregon Health & Science University Receives a 2017 NIH Grant for $414,360 for Dynamic Changes in the Chick Developing Heart in Response to Altered Hemodynamics. The principal investigator is Sandra Rugonyi. The program began in 2008 and ends in 2018. Below is a summary of the proposed work. Project Summary About 1% newborn babies have congenital heart disease (CHD), the leading cause of death among children. The majority of CHD cases are believed not to have a genetic cause. Other factors, such as abnormal blood flow during embryonic and fetal stages can lead to heart malformations and thus CHD through ...

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