1. Articles in category: Funding

    1-24 of 431 1 2 3 4 ... 16 17 18 »
    1. University of Texas, Austin Receives NIH Grant for Optical Imaging of Baseline Blood Flow and Oxygenation During Stroke

      University of Texas, Austin Receives NIH Grant for Optical Imaging of Baseline Blood Flow and Oxygenation During Stroke

      University of Texas, Austin Receives a 2015 NIH Grant for $465,127 for Optcial Imaging of Baseline Blood Flow and Oxygenation During Stroke. The principal investigator is Andrew Dunn. The program began in 2010 and ends in 2019. Below is a summary of the proposed work. Quantitative imaging of cerebral blood flow is essential in preclinical stroke studies for monitoring the efficacy of potential treatments and for understanding the role of vascular reorganization in functional recovery. Similarly, real-time imaging of blood flow is crucial during neurovascular surgery in humans, where intraoperative visualization of vascular patency and tissue perfusion are needed ...

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    2. National Research Council of Canada Receives NIH Grant for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization

      National Research Council of Canada Receives NIH Grant for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization

      National Research Council of Canada Receives NIH Grant for $208,382 for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization. The principal investigator is Michale Sowa. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Dental caries continues to be prevalent in children and youth, with significant oral health disparities existing in some population groups. This disease arises when the balance between pathological factors (e.g. cariogenic bacteria) and protective factors (e.g. saliva flow) is tipped in favour of demineralization. The prevalence of caries suggests that the disease ...

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    3. Stanford University Receives a NIH Grant for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo

      Stanford University Receives a  NIH Grant for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo

      Stanford University Receives a 2015 NIH Grant for $448,758 for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo. The principal investigator is John Oghalai. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. The function of the cochlea is to transduce complex sound pressure waves into electrical signals. Organ of Corti vibration is based upon a complex interplay between passive mechanical structures and active OHC- based processes. While laser Doppler vibrometry has added tremendously to our understanding of cochlear physiology, this technique is limited. Only motion from one ...

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    4. Georgetown University Receives NIH Grant for Non-Invasive Evaluation of Transplant Kidney using OCT

      Georgetown University Receives NIH Grant  for Non-Invasive Evaluation of Transplant Kidney using OCT

      Georgetown University Receives a 2015 NIH Grant for $388,865 for Non-Invasive Evaluation of Transplant Kidney using OCT. The principal investigator is Peter Andrews. The program began in 2014 and ends in 2016. Below is a summary of the proposed work. There is currently a worldwide shortage of kidneys for transplantation due mainly to the fact that there is no reliable means to determine their viability (i.e., kidneys stored for long periods of time, etc.). Also, following transplantation, kidneys oftn do not function immediately and their status is unclear. Previously, we have shown that the histopathology of living, superficial ...

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    5. Duke University Receives NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health

      Duke University Receives NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health

      Duke University Receives a 2015 NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health. The principal investigator is David Katz. The program began in 2012 and ends in 2016. Below is a summary of the proposed work. Vaginal microbicides offer much promise to prevent sexual transmission of HIV. The pharmacokinetics (PK) of a product (active pharmaceutical ingredient + dosage form) is central to prophylactic functionality (PD). But our ability to measure and predict microbicide PK is currently limited. Further, microbicide PD depends on how product + dosage regimen accommodate a range of conditions of the vaginal environment. These ...

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      Mentions: Duke University
    6. Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography. The principal investigator is James Fujimoto. The program began in 1985 and ends in 2020. Below is a summary of the propose work. This proposal is a resubmission of a competing renewal application for an ongoing collaborative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye Center. This is a multidisciplinary program which integrates imaging technology research, clinical and small animal imaging studies. The specific aims are: Aim 1. Next generation OCT technology ...

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    7. UC Irvine Receives a 2015 NIH grant for Combined OCT/US/PAT System for Intravascular Imaging

      UC Irvine Receives a 2015 NIH grant for Combined OCT/US/PAT System for Intravascular Imaging

      University of California Irvine Receives a 2015 NIH grant for Combined OCT/US/PAT System for Intravascular Imaging. The principal investigator is Zhongping Chen. The program begain in 2015 and ends in 2019. Below is a summary of the propose work.

      Atherosclerosis is a progressive disease that is characterized by the accumulation of lipids, cholesterol, fibrous constituents, monocytes, and various other inflammatory cells in the arterial wall. Atherosclerosis is one of the major causes of morbidity and mortality in developed countries. The major cause of deaths from heart attacks (86%) and brain aneurysm (45%) are due to "vulnerable plaques" that ...

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    8. VA North Texas Health Care System Receives NIH Grant for Prasugrel for Prevention of Early Saphenous Vein Grant Thrombosis.

      VA North Texas Health Care System Receives NIH Grant for Prasugrel for Prevention of Early Saphenous Vein Grant Thrombosis.

      VA North Texas Health Care System Receives a 2015 NIH Grant for Prasugrel for Prevention of Early Saphenous Vein Grant Thrombosis. The principal investigator is Emmanouil Brilakis. The program began in 2012 and ends in 2016. Below is a summary of the proposed work. Early aortocoronary saphenous vein bypass graft (SVG) failure is common and is associated with high morbidity and mortality. Aspirin significantly reduces the incidence of early saphenous vein graft failure, whereas clopidogrel use provided conflicting results in small randomized studies. Prasugrel is a novel thienopyridine that provides more rapid, consistent, and intense platelet inhibition than clopidogrel. However ...

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    9. Texas Engineering Experiment Station Receives NIH Grant for Morphological and Molecular Imaging System for In Vivo Atherosclerosis Research

      Texas Engineering Experiment Station Receives NIH Grant for Morphological and Molecular Imaging System for In Vivo Atherosclerosis Research

      Texas Engineering Experiment Station Receives a 2015 NIH Grant for Morphological and Molecular Imaging System for In Vivo Atherosclerosis Research. The Principal invesigator is Brian Applegate. The program began in 2012 and ends in 2017. Below is a summary of the proposed work.

      Atherosclerosis is the leading cause of morbidity and mortality in the United States and is characterized as a systemic, progressive disease process in which the arterial wall thickens through a process of inflammation, oxidative stress, and dyslipidemia. This process leads to plaque formation and flow limitation in the vessel lumen. The sudden rupture of this arterial plaques ...

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    10. Columbia University Receives NIH Grant for Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration

      Columbia University Receives NIH Grant for Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration

      Columbia University Receives a 2015 NIH Grant for $281,840 for Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration. The principal investigator is Ronald Silverman. The program began in 2012 and ends in 2016. Below is a summary of the proposed work. Age-related macular degeneration (AMD) is a disease of the retinal pigment epithelium characterized by the appearance of protein/lipid deposits (drusen), geographic atrophy and neovascularization. Techniques currently used for diagnostic imaging of AMD include indocyanine green dye or fluorescein angiography, autofluorescence imaging and optical coherence tomography (OCT). OCT images depict optical backscatter, caused by variation in ...

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    11. “How Does Breast Cancer Develop?” Pilot Grants Awarded to Multidisciplinary Teams Using the Intraductal Approach to Advance Breast Cancer Prevention

      “How Does Breast Cancer Develop?” Pilot Grants Awarded to Multidisciplinary Teams Using the Intraductal Approach to Advance Breast Cancer Prevention

      Dr. Sheldon Feldman and Dr. Fatih Balci study intraductal approaches to breast cancer. They are currently investigating the effectiveness of optical coherence tomography (OCT), which is used in cardiology to look at blood vessels from the inside using light instead of sound (as an ultrasound does) to create three-dimensional images. OCT may be able to identify early changes in the breast duct before ductal carcinoma in situ (DCIS) or cancer forms. This consortium received $17,000 to study whether it is feasible to use OCT to distinguish different types of breast cells and tissues and whether OCT can show features ...

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    12. Wasatch Photonics Receives NIH SBIR for a Hand-Held Advanced Functional Imaging for Assessing Local Tissue Oxygenation

      Wasatch Photonics Receives NIH SBIR for a Hand-Held Advanced Functional Imaging for Assessing Local Tissue Oxygenation

      Wasatch Photonics Received a 2015 NIH SBIR for $149,950 for a Hand-Held Advanced Functional Imaging for Assessing Local Tissue Oxygenation. The principal investgator is Roman Kuranov. The program began in 2015 and ends in 2015. Below is a summary of the purposed work. We propose development of an advanced functional imager to assess red blood cell (RBC) transfusion. The prototype will be tested in a functional phantom during this SBIR Phase I project. The key features of the imager are the ability to quantify local tissue oxygenation with a handheld probe for easy tissue access. Our preliminarily market research ...

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    13. Florida International University Received a 2015 NIH Grant Multimodal Retinal Functional Imaging for Diabetic Retinopathy

      Florida International University Received a 2015 NIH Grant Multimodal Retinal Functional Imaging for Diabetic Retinopathy

      Florida International University Received a 2015 NIH Grant for $542,882 for Multimodal Retinal Functional Imaging for Diabetic Retinopathy. The principal investigator is Shuliang Jiao. The program begain in 2013 and ends in 2016. Below is a summary of the proposed work. Diabetic retinopathy (DR) is a leading cause of irreversible blindness among working-age adults, which is a typical type of ischemia driven retinal disease characterized by microvascular damage to the retina in patients with diabetes. DR progresses through a sequence of recognizable stages, which begin with structural and functional derangement of the retinal microcirculation even before the early clinical ...

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    14. Bioptigen Receives NIH Grant for Intrasurgical Optical Coherence Tomography

      Bioptigen Receives NIH Grant for Intrasurgical Optical Coherence Tomography

      Bioptigen Received a 2015 NIH Grant for $995,139 for Intrasurgical Optical Coherence Tomography. The principal investigator is Eric Buckland. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. Each year, over 20 million ophthalmic surgeries are performed worldwide. Indications for ophthalmic surgery include potentially blinding diseases, such as cataracts, diabetic retinopathy, macular disease, and retinal detachment. Surgeons performing these delicate procedures are challenged by the translucent nature of tissues in the eye, making it nearly impossible to visualize microstructural changes during surgery. Optical coherence tomography (OCT) is a non-contact, optical imaging ...

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    15. OCT firm Michelson Diagnostics closes £2.5m 'Series B' funding

      OCT firm Michelson Diagnostics closes £2.5m 'Series B' funding

      Michelson Diagnostics , the UK-based medical device company focused on multi-beam Optical Coherence Tomography technology, has closed the £2.5m first tranche of its “Series B” financing, led by strategic investor and medical specialist Smith & Nephew alongside new investor Kent County Council as well as existing investors. The £2.5m investment will be used to expand Michelson Diagnostics’ commercial presence in Germany; launch the Company’s next generation VivoSight OCT tissue-imaging system; complete the ongoing US multi-center clinical biopsy avoidance study; and explore further applications in wound care and dentistry. VivoSight is a point-of-care tissue-imaging system that for the first time ...

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    16. Spectrum awards more than $1.1 million in pilot grants to 32 projects

      Spectrum awards more than $1.1 million in pilot grants to 32 projects

      Thirty-two biomedical teams at Stanford have received about $1.1 million in research funding through the Spectrum pilot grant program. Spectrum , the Stanford Center for Clinical and Translational Research and Education, is focused on accelerating the translation of medical research from bench to bedside. Its pilot grants are awarded to investigators with bold ideas that address health-care problems through novel approaches and multidisciplinary teams. This year, grants were awarded in five areas: medical technologies; therapeutics; population health; community engagement; and predictive tools and diagnostics. Grants awarded through the Stanford Health Care Innovation Challenge, a new subcategory under population health, went ...

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    17. University of Miami Receives NIH Grant for Advanced Imaging for Diabetic Retinopathy

      University of Miami Receives NIH Grant  for Advanced Imaging for Diabetic Retinopathy

      University of Miami Receives a 2015 NIH Grant for $155,387 for Advanced Imaging for Diabetic Retinopathy. The principal investigator is Delia Cabrera Debuc. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Diabetic retinopathy (DR) is a major cause of visual loss in diabetic individuals that presents a significant diagnostic challenge. Advances in preventing vision loss in these individuals are hindered by limited understanding of mechanisms underlying DR and the altered relationships between the retinal neural tissue and retinal vasculature. Therefore, an objective test for the early diagnosis and evaluation of ...

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    18. Michelson Diagnostics closes £2.5 million First Tranche of £4.0 million Series B fundraising Smith & Nephew as Cornerstone Investor

      Michelson Diagnostics closes £2.5 million First Tranche of £4.0 million Series B fundraising Smith & Nephew as Cornerstone Investor

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, is pleased to announce that it has closed the £2.5 million First Tranche of its Series B financing. This was led by strategic investor, global medical technology business Smith & Nephew and included new investor Kent County Council as well as existing investors. The £2.5 million investment will be used to expand the Michelson Diagnostics’ commercial presence in Germany; launch the Company’s next generation VivoSight OCT tissue-imaging system; complete the ongoing US multi-centre clinical biopsy avoidance study and explore further applications of ...

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    19. Smith & Nephew bets on technology that 'sees through the skin'

      Smith & Nephew bets on technology that 'sees through the skin'

      Smith & Nephew has bet on a new technology that enables doctors to "see through the skin", in the hope that it could be used by the company's growing wound care business. The med tech giant has invested £1.25m in Michelson Diagnostics, a small Kent-based business which uses laser beams to produce high resolution images of cells beneath the surface of the skin. Michelson's Vivosight system is already being used in place of biopsies to diagnose non-melanoma skin cancer , a less aggressive but more common variety of the disease compared with more deadly melanoma skin cancers. But the ...

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    20. University of Washington Receives NIH Grant to Study Non-invasive Real-Time Label-Free 3D Imaging of Retinal Microcirculation.

      University of Washington Receives NIH Grant to Study Non-invasive Real-Time Label-Free 3D Imaging of Retinal Microcirculation.

      University of Washington Received a 2015 NIH Grant to Study Non-invasive real-time label-free 3D imaging of retinal microcirculation. The principal investigator is Ruikang Wang. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. Non-invasive and label-free imaging techniques for assessing retinal blood perfusion in humans - down to capillary-level resolution, are of paramount importance for improved understanding, diagnosis, treatment and management of diseases that have a vascular component in their pathogenesis, e.g., age related macular degeneration (AMD), diabetic retinopathy (DR), and open angle glaucoma (OAG). Invasive imaging techniques, e.g., fluorescein angiography ...

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    21. Medical College of Wisconsin Receives NIH Grant to study Inhibition of Reflux-Induced Esophageal Adenocarinoma by Proanthocyanidins.

      Medical College of Wisconsin Receives NIH Grant  to study Inhibition of Reflux-Induced Esophageal Adenocarinoma by Proanthocyanidins.

      Medical College of Wisconsin Received a 2015 NIH Grant for $317,475 to study Inhibition of Reflux-Induced Esophageal Adenocarinoma by Proanthocyanidins. The prinipal investigator is Laura Kreesty. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Esophageal adenocarcinoma (EAC) rates have increased 500% over the last three decades resulting in EAC being identified as the fastest increasing of all cancer types in the US. Esophageal cancer is an extremely deadly malignancy with 5-year survival rates consistently under 20%. The precise reasons for increasing rates of EAC are an active area of investigation ...

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    22. Emanuel Hospital and Health Center Receives NIH Grant for Optical Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital and Health Center Receives NIH Grant  for Optical Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital and Health Center Received a 2015 NIH Grant for $553,852 for Optical Nerve Head SD-OCT Imaging in Glaucoma. The principal investigator is Claude Burgoyne. The program begain in 2010 and ends in 2019. Below is a summary of the proposed work. As a result of discoveries made during the first project period, we propose a paradigm change for clinical assessment of the Optic Nerve Head (ONH), peripapillary retinal nerve fiber layer (RNFL) and macula based on acquisition and regionalization of Spectral Domain Optical Coherence Tomography (SDOCT) ONH, RNFL and macula datasets relative to the axis between the ...

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    23. Horizon Technology Finance Leads $15 Million Venture Loan Facility for NinePoint Medical

      Horizon Technology Finance Leads $15 Million Venture Loan Facility for NinePoint Medical

      Horizon Technology Finance Corporation ("Horizon") ( HRZN ), a leading specialty finance company that provides capital in the form of secured loans to venture capital backed companies in the technology, life science, healthcare information and services, and cleantech industries, today announced it has led a $15 million venture loan facility for NinePoint Medical, Inc. ("NinePoint"), an emerging leader in the development of medical devices for advanced optical imaging. NinePoint will use the proceeds for working capital purposes. Horizon funded an initial $5 million of its $7.5 million commitment under the venture loan facility. "We are pleased to lead a $15 million ...

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    24. Procedural Optical Coherence Tomography (OCT) For Surgery And Related Systems And Methods

      Procedural Optical Coherence Tomography (OCT) For Surgery And Related Systems And Methods

      Methods for performing a surgical procedure using optical coherence tomography (OCT) are provided. The method includes orienting the subject for the surgical procedure, wherein orienting comprises imaging a region of the subject that contains a structure having a known orientational asymmetry, testing the image for the presence and location of the structure, and confirming correct orientation of the subject using the OCT image of the structure having the known orientational asymmetry; obtaining at least one image of the surgical region of the subject using OCT and constructing an initial structural view of the surgical region; computing at least one clinical ...

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    1-24 of 431 1 2 3 4 ... 16 17 18 »
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