1. Articles in category: Pulmonology

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    1. In vivo Optical Coherence Tomography Imaging of Preinvasive Bronchial Lesions

      Purpose: Optical coherence tomography (OCT) is an optical imaging method that can visualize cellular and extracellular structures at and below tissue surface. The objective of the study was to determine if OCT could characterize preneoplastic changes in the bronchial epithelium identified by autofluorescence bronchoscopy. Experimental Design: A 1.5-mm fiberoptic probe was inserted via a bronchoscope into the airways of 138 volunteer heavy smokers participating in a chemoprevention trial and 10 patients with lung cancer to evaluate areas that were found to be normal or abnormal on autofluorescence bronchoscopy. Radial scanning of the airways was done to generate OCT images ...
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    2. Optical Biopsy Characterizing Tissue While Its in the Body

      Cover Story Table of Contents E-Newsletter Article Archive Editorial Calendar Datebook Writers' Guidelines Orgs/Links Opinion Polls Reprints Forum Lung cancer patients face the possibility that it could be more than two months from the time their cancer is first suspected from a chest x-ray or CT or PET scan until their diagnosis is confirmed and treatment begun. “By the time the patients go through six different appointments and getting this test and that, it could be 70 to 80 days until they a
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    3. Airway Wall Thickness Assessed Using Computed Tomography and Optical Coherence Tomography

      Airway Wall Thickness Assessed Using Computed Tomography and Optical Coherence Tomography

      Rationale: Computed tomography (CT) has been shown to reliably measure the airway wall dimensions of medium to large airways. Optical coherence tomography (OCT) is a promising new micron-scale resolution imaging technique that can image small airways 2 mm in diameter or less. Objectives: To correlate OCT measurements of airway dimensions with measurements assessed using CT scans and lung function. Methods: Forty-four current and former smokers received spirometry, CT scans, and OCT imaging at the time of bronchoscopy. Specific bronchial segments were identified and measured using the OCT images and three-dimensional reconstructions of the bronchial tree using CT. Measurements and Main ...

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    4. Anatomical optical coherence tomography: a safe and effective tool for quantitative long-term monitoring of upper airway size and shape

      J. J. Armstrong, S. Becker, R. A. McLaughlin et al. Anatomical optical coherence tomography (aOCT) is an endoscopic optical technique that enables continuous, quantitative assessment of hollow organ size and shape in three dimensions. It is a powerful alternative to X-ray computed tomography, magnetic resonance imaging, and video endoscopy for the as ... [Proc. SPIE Int. Soc. Opt. Eng. 6842, 68421N (2008)] published Fri Feb 8, 2008.
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    5. Imaging of the Pediatric Airway Using Optical Coherence Tomography.

      Laryngoscope. 117(12):2206-2212, December 2007. Ridgway, James Matthew MD; Ahuja, Gurpreet MD; Guo, Shuguang PhD; Su, Jianping BS; Mahmood, Usama BS; Chen, Zhongping PhD; Wong, Brian MD, PhD Abstract: Objectives: Optical coherence tomography (OCT) is an imaging modality that uses a broadband light source to produce high-resolution cross-sectional images in living tissue (8-20 [mu]m). A prospective study of normal, benign, and pathologic tissues in the pediatric airway was conducted to assess the
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    6. Radiation dose could be cut for pulmonary embolism scans of pregnant patients

      Pulmonary embolism and other conditions may be detected in pregnant women using lower radiation doses than is currently standard, according to studies presented at the RSNA meeting on Monday. New techniques show promise, but obstacles such as small study populations and the lack of prospective trials must be overcome before a definitive protocol can be devised.
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    7. Tomophase to Exhibit First Cross-Sectional Images of Human Bronchus Using Proprietary OCT System

      【字体:大 中 小】 】   BURLINGTON, Mass., Oct. 17 /PRNewswire/ -- Tomophase Corporation announced today that it will display the first cross-sectional images of excised human bronchial tissue using their patented optical coherence tomography ("OCT") system at the CHEST meeting in Chicago, October 22nd through October 24th. The images were captured using the Tomophase OCT system as part of an ongoing research collaboration with Dr. Armin Ernst, Director of Interventional Pulmonology, at Be
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    8. Detection of acute smoke-induced airway injury in a New Zealand white rabbit model using optical coherence tomography

      Matthew Brenner, Kelly Kreuter, David Mukai et al. Optical coherence tomography (OCT) is a micron scale high-resolution optical technology that can provide real-time in vivo images noninvasively. The ability to detect airway mucosal and submucosal injury rapidly will be valuable for a range of pulmonary applications including assessment of acute inh ... [J. Biomed. Opt. 12, 051701 (2007)] published Mon Oct 29, 2007.
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    9. Optical Coherence Tomography of Airway and Pleural Disorders

      Optical methods for obtaining images in airway passages for early detection of endobronchial lung and pleural cancer are needed. Optical coherence tomography (OCT) is a non-invasive or minimally invasive diagnostic technique that can provide information about tissue abnormalities. OCT can produce images of abnormalities both at and below the surface of the airways without damaging the tissue surface This technique uses a harmless device to emit infrared (not visible) light that can produce images of the specimen under investigation without causing damage or alterations
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    10. OCT for Early Detection and Staging of Endobronchial Lung and Pleural Cancer, Airway Injury, and Prostate Cancer

      Optical coherence tomography (OCT) is a non-invasive diagnostic technique that can provide information about tissue abnormalities. This technique uses a near-infrared diode to emit light that can produce images of the specimen under investigation without causing damage or alterations. The research' want to compare the OCT results with that obtained from conventional histologic examination and to show that the OCT results may be almost as accurate as the standard Pathology results. Optical coherence tomography (OCT) is a new technique being developed that can be used for visualizing human tissue. OCT offers a means of providing information on the characteristics and ...
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    11. Anatomical optical coherence tomography in the human upper airway (Thesis)

      Anatomical optical coherence tomography in the human upper airway (Thesis)
      This thesis describes the development, clinical validation and initial application of a technique for taking measurements of the shape and dimensions of the human upper airway, called anatomical optical coherence tomography (aOCT). The technique uses a transparent catheter containing a rotating optical probe which is introduced transnasally and positioned in the airway and oesophagus. Optical coherence tomography is used to take calibrated cross-sectional images of the airway lumen as the probe rotates. The probe can also be advanced or withdrawn within the catheter during scanning to build up three-dimensional information. The catheter remains stationary so that the subject is not ...
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    12. Apparatus for in vivo imaging of the respiratory tract and other internal organs

      Apparatus for acquiring in vivo images of a site of interest within the internal organs of a body. The apparatus includes an elongate, flexible catheter. The catheter is introducible into the body and has a first end that remains external to the body and a second and positionable adjacent the site of interest. A movable scanning unit having at least one sensor for acquiring images is housed adjacent the second end of the catheter. There is a drive mechanism to control movement of the movable scanning unit from the first external end of the catheter to acquire multiple images of ...
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    217-229 of 229 « 1 2 3 4 5 6 7 8 9 10
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