1. Articles in category: Ophthalmology

    12913-12936 of 13125 « 1 2 ... 536 537 538 539 540 541 542 ... 545 546 547 »
    1. Foveal dysplasia evident by optical coherence tomography in patients with a history of retinopathy of prematurity.

      Related Articles Foveal dysplasia evident by optical coherence tomography in patients with a history of retinopathy of prematurity. Retina. 2007 Nov-Dec;27(9):1221-6 Authors: Recchia FM, Recchia CC PURPOSE: To describe the optical coherence tomography (OCT) findings for patients with a history of retinopathy of prematurity (ROP). METHODS: Clinical records, fundus photographs, and OCT findings for consecutive patients aged 8 years and older who had a history of ROP were reviewed. The main outcome measures were best-corrected visual acuity, central foveal thickness (CFT), macular anatomy, and foveal contour by OCT. RESULTS: Twenty eyes of 12 patients (median age, 15 ...
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    2. Long-term outcomes of macular hole surgery with triamcinolone acetonide-assisted internal limiting membrane peeling.

      PURPOSE: To report long-term anatomical and functional results after pars plana vitrectomy with internal limiting membrane (ILM) peeling using triamcinolone acetonide (TA) for idiopathic macular holes. DESIGN: Prospective, consecutive, interventional case series. METHODS: Ninety-six eyes of 94 patients who underwent macular hole surgery with TA-assisted ILM peeling were included in the study. Patients with PMID: 18046233 [PubMed - in process]
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    3. Racial differences in macular thickness in healthy eyes.

      Related Articles Racial differences in macular thickness in healthy eyes. Optom Vis Sci. 2007 Oct;84(10):941-5 Authors: Asefzadeh B, Cavallerano AA, Fisch BM PURPOSE: The relationship between race and macular thickness remains unknown. This relationship may be important for early and accurate diagnosis of macular disease and glaucoma, and may also provide insight into disease mechanisms. In this study, we compared macular thickness in healthy eyes of black and white subjects using optical coherence tomography (Stratus OCT). METHODS: This study used a matched, cross-sectional design. Subjects underwent OCT macular thickness map scanning in each eye, four-field, 45-degree digital ...
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    4. New technologies to assess lens-mediated effects of the cornea.

      Related Articles New technologies to assess lens-mediated effects of the cornea. Eye Contact Lens. 2007 Nov;33(6 Pt 2):364-70; discussion 382 Authors: Fonn D, Simpson T, Woods J, Woods C Contact lenses can affect the cornea in a variety of ways. Corneal structure can be altered so that its thickness changes to involve the epithelium and the stroma. As a result, the curvature may be affected, but whether it is the front or the back surface that is affected depends on the type of lens used. If thickness increases sufficiently, corneal transparency may decrease. Contact lenses can also ...
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    5. Can optical coherence tomography predict the outcome of laser photocoagulation for diabetic macular edema?

      Related Articles Can optical coherence tomography predict the outcome of laser photocoagulation for diabetic macular edema? Ophthalmic Surg Lasers Imaging. 2007 Nov-Dec;38(6):478-83 Authors: Estabrook EJ, Madhusudhana KC, Hannan SR, Newsom RS BACKGROUND AND OBJECTIVE: To assess the outcome of laser photocoagulation in patients with diabetic macular edema. PATIENTS AND METHODS: Forty-seven patients (51 eyes) with clinically significant macular edema (CSME) undergoing grid laser photocoagulation were included. Clinical examination and optical coherence tomography (OCT) were performed at baseline and 3 to 4 months after treatment. The central foveal thickness, mean inner macular thickness (average retinal thickness in fovea ...
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    6. Optical coherence tomography demonstration of Best's vitelliform macular dystrophy in a child.

      Related Articles Optical coherence tomography demonstration of Best's vitelliform macular dystrophy in a child. Ophthalmic Surg Lasers Imaging. 2007 Nov-Dec;38(6):511-3 Authors: Al-Kahtani E, Nowilaty SR Considering the importance of optical coherence tomography in clinical decision making, the veracity of these images is critical. The authors describe a 5-year-old girl with Best's vitelliform macular dystrophy of different stages of development in both eyes in which the optical coherence tomography appearance correlated well with both the staves of the disease and the visual function. PMID: 18050818 [PubMed - indexed for MEDLINE]
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    7. Optical coherence tomography of corneal and scleral melts.

      Related Articles Optical coherence tomography of corneal and scleral melts. Ophthalmic Surg Lasers Imaging. 2007 Nov-Dec;38(6):514-7 Authors: Reddy HS, Li Y, Yiu SC, Irvine JA, Huang D Corneal and scleral melts can be difficult to assess by slit-lamp due to the overlying opacity. The authors demonstrate the role of optical coherence tomography (OCT) in the diagnosis and management of two cases of corneal and scleral melt. A high-speed anterior segment OCT system operating at a 1310-nm wavelength was used. Cross-sectional OCT images showed the depth and extent of the melt. OCT images were obtained through an opaque ...
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    8. Use of varying constraints in optimal 3-D graph search for segmentation of macular optical coherence tomography images.

      An optimal 3-D graph search approach designed for simultaneous multiple surface detection is extended to allow for varying smoothness and surface interaction constraints instead of the traditionally used constant constraints. We apply the method to the intraretinal layer segmentation of 24 3-D optical coherence tomography (OCT) images, learning the constraints from examples in a leave-one-subject-out fashion. Introducing the varying constraints decreased the mean unsigned border positioning errors (mean error of 7.3 +/- 3.7 microm using varying constraints compared to 8.3 +/- 4.9 microm using constant constraints and 8.2 +/- 3.5 microm for the inter-observer variability).
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    9. Primary intravitreal bevacizumab for the management of pseudophakic cystoid macular edema: pilot study of the Pan-American Collaborative Retina Study Group.

      Related Articles Primary intravitreal bevacizumab for the management of pseudophakic cystoid macular edema: pilot study of the Pan-American Collaborative Retina Study Group. J Cataract Refract Surg. 2007 Dec;33(12):2098-105 Authors: Arevalo JF, Garcia-Amaris RA, Roca JA, Sanchez JG, Wu L, Berrocal MH, Maia M, PURPOSE: To determine the feasibility, safety, and clinical effect of primary intravitreal bevacizumab (Avastin) in patients with cystoid macular edema (CME) after cataract surgery. SETTING: Five institutions in Venezuela, Costa Rica, Puerto Rico, Peru, and Brazil. METHODS: Twenty-eight eyes of 25 patients treated with at least 1 intravitreal injection of 1.25 mg or ...
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    10. Results of penetrating keratoplasty performed with a femtosecond laser zigzag incision initial report.

      Related Articles Results of penetrating keratoplasty performed with a femtosecond laser zigzag incision initial report. Ophthalmology. 2007 Dec;114(12):2208-12 Authors: Farid M, Kim M, Steinert RF PURPOSE: To determine the initial outcomes of utilizing a femtosecond laser to perform penetrating keratoplasty incisions in a zigzag pattern. DESIGN: Retrospective consecutive surgical series. PARTICIPANTS: Patients undergoing full-thickness corneal transplant surgery in a referral academic practice. METHODS: The IntraLase femtosecond laser performed matching donor and host zigzag incisions in a consistent pattern in 13 eyes of 13 patients. MAIN OUTCOME MEASURES: Topographically determined astigmatism, imaging of incisions by anterior segment optical ...
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    11. Optical Coherence Tomography Features During the Evolution of Serous Retinal Detachment in Patients with Diabetic Macular Edema.

      PURPOSE: To characterize the evolution of serous retinal detachment (SRD) combined with diabetic macular edema (DME) using optical coherence tomography (OCT). DESIGN: Observational retrospective case series. METHODS: In our institution, 64 eyes of 40 diabetic patients who had SRD combined with DME were studied. All patients had fluorescein angiography and several OCT3 examinations during follow-up. Foveolar neuroretinal thickness (NRT) and SRD height were measured. The evolution of OCT macular profiles was qualitatively assessed. RESULTS: Mean follow-up was 11.8 months. DME was focal in 10 eyes (15.6%), diffuse in 17 (26.6%) and both diffuse and focal in 37 ...
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    12. Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography vs Ultrasound Pachymetry.

      PURPOSE: To determine if there is a systematic difference in central corneal thickness (CCT) measured using anterior segment optical coherence tomography (AS-OCT) as compared with ultrasound pachymetry. DESIGN: Prospective observational study. METHODS: Consecutive subjects with clinically normal corneas underwent CCT measurement by both ultrasound and AS-OCT while participating in a population-based study in Ghana, West Africa. One eye of each subject was randomly selected for analysis. Two measurements were taken and averaged. Agreement and interobserver variability were also analyzed. RESULTS: One hundred and fifty-five subjects of African ethnicity and average age 57 years (standard deviation [SD] 12; range, 40 to ...
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    13. Retinal nerve fiber layer thickness is associated with brain MRI outcomes in multiple sclerosis.

      Multiple sclerosis is characterized by the dual pathological processes of inflammation and neurodegeneration. Conventional MRI techniques are considered the best tools for assessing and monitoring lesion burden and inflammation but are limited in their ability to assess axonal loss. Optical coherence tomography (OCT) is a simple high-resolution technique that uses near infrared light to quantify the thickness of the retinal nerve fiber layer (RNFL), which contains only non-myelinated axons. RNFL thickness (RNFLT) was measured using OCT on thirty consecutive MS patients (60 eyes). Eighteen patients underwent quantitative MRI analysis including T1- and T2-lesion volumes (LV), normalized brain volume (NBV), normalized ...
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    14. Repeatability and reproducibility of pachymetric mapping with visante anterior segment optical coherence tomography.

      PURPOSE: To determine the repeatability and reproducibility of central and peripheral corneal pachymetry mapping with anterior segment-optical coherence tomography (AS-OCT). METHODS: An observational cross-sectional study involving two groups: 27 healthy eyes and 20 eyes with keratoconus. Each subject underwent scanning sessions with AS-OCT to determine intraobserver repeatability, interobserver reproducibility, and additionally for healthy eyes, intersession reproducibility for different regions of the cornea up to a 10-mm diameter. Main outcome measures were reproducibility and repeatability coefficients, intraclass correlation coefficients, and coefficients of variation of the average central (0-2 mm), pericentral (2-5 mm), transitional (5-7 mm), and peripheral (7-10 mm) corneal thicknesses ...
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    15. Is optical coherence tomography really a new biomarker candidate in multiple sclerosis? A structural and functional evaluation.

      Related Articles Is optical coherence tomography really a new biomarker candidate in multiple sclerosis? A structural and functional evaluation. Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5773-81 Authors: Gundogan FC, Demirkaya S, Sobaci G PURPOSE: To assess the structural and functional status of patients with multiple sclerosis (MS) without a history of optic neuritis. METHODS: Thirty-nine patients with MS who had reported no visual symptoms before and after the time of MS diagnosis were included. Thirty-eight healthy subjects were included as a control group. Retinal nerve fiber layer (RNFL) thickness was determined by optical coherence tomography. Pattern visual evoked ...
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    16. The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits.

      Related Articles The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5708-15 Authors: Ameri H, Chader GJ, Kim JG, Sadda SR, Rao NA, Humayun MS PURPOSE: To evaluate the effects of intravitreous bevacizumab in a rabbit retinal neovascularization model. METHODS: Twenty-four rabbits were divided into five groups. Group A included four rabbits; all other groups included five rabbits each. Group A received intravitreous VEGF only, and group E received intravitreous bevacizumab only. In groups B, C, and D, bevacizumab was injected at the same time, at day ...
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    17. The Relationship between Visual Field and Retinal Nerve Fiber Layer Measurements in Patients with Multiple Sclerosis.

      Related Articles The Relationship between Visual Field and Retinal Nerve Fiber Layer Measurements in Patients with Multiple Sclerosis. Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5798-805 Authors: Cheng H, Laron M, Schiffman JS, Tang RA, Frishman LJ PURPOSE: To investigate the relationship between visual function, measured by standard automated perimetry (SAP), and retinal nerve fiber layer (RNFL) thickness, measured by optical coherence tomography (OCT), in patients with multiple sclerosis (MS). METHODS: SAP and RNFL thickness were measured in patients with MS in 28 eyes with the last optic neuritis (ON) >/=6 months prior (ON group) and 33 eyes without ...
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    18. An investigation of the retinal nerve fibre layer in progressive multiple sclerosis using optical coherence tomography.

      Related Articles An investigation of the retinal nerve fibre layer in progressive multiple sclerosis using optical coherence tomography. Brain. 2007 Dec 4; Authors: Henderson AP, Trip SA, Schlottmann PG, Altmann DR, Garway-Heath DF, Plant GT, Miller DH Axonal loss is thought to be the predominant cause of disability in progressive multiple sclerosis (MS). The retinal nerve fibre layer (RNFL) is composed largely of unmyelinated axons of retinal ganglion cells, and is accessible to study with optical coherence tomography (OCT), giving a measure of axonal loss. OCT measures of the RNFL thickness (RNFLT) and macular volume were studied in 23 patients ...
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    19. Parallel optical coherence tomography system.

      Related Articles Parallel optical coherence tomography system. Appl Opt. 2007 Dec 1;46(34):8291-7 Authors: Luo Y, Arauz LJ, Castillo JE, Barton JK, Kostuk RK We present the design and procedures for implementing a parallel optical coherence tomography (POCT) imaging system that can be adapted to an endoscopic format. The POCT system consists of a single mode fiber (SMF) array with multiple reduced diameter (15 mum) SMFs in the sample arm with 15 mum center spacing between fibers. The size of the array determines the size of the transverse imaging field. Electronic scanning eliminates the need for mechanically scanning ...
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    20. Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography.

      Related Articles Use of a scanner to modulate spatial interferograms for in vivo full-range Fourier-domain optical coherence tomography. Opt Lett. 2007 Dec 1;32(23):3423-5 Authors: An L, Wang RK We report a new yet simple method to achieve full-range complex Fourier-domain optical coherence tomography (OCT) for in vivo imaging. The method utilizes a scanner that is dedicated for lateral scanning in the system to introduce a constant carrier frequency into the OCT spectral interferograms during the scanning. This is achieved by simply offsetting the sampling beam spot away from the pivot point of the scanning mirror. We demonstrate ...
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