1. Articles in category: Ophthalmology

    12889-12912 of 13133 « 1 2 ... 535 536 537 538 539 540 541 ... 546 547 548 »
    1. Correlation between retinal nerve fibre layer thickness and retinal sensitivity

      Purpose: To evaluate the relationship between retinal nerve fibre layer (RNFL) thickness measured by optical coherence tomography (OCT) and light threshold values obtained with the Micro Perimeter 1 (MP1). Methods: Forty-nine normal subjects and 37 glaucoma patients were included. Thickness of the RNFL around the optic disc was measured with Stratus OCT scans, and static threshold perimetry was performed with the MP1 at the same visit. Total average and mean 12-clock-hour RNFL thickness were measured with Stratus OCT. An automated 4-2-1 staircase strategy with Goldmann III stimuli was used for MP1. The correspondence between Stratus OCT and MP1 RNFL measurements ...
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    2. Accuracy of cornea and lens biometry using anterior segment optical coherence tomography

      Mark C. M. Dunne, Leon N. Davies, and James S. Wolffsohn We assess the accuracy of the Visante anterior segment optical coherence tomographer (AS-OCT) and present improved formulas for measurement of surface curvature and axial separation. Measurements are made in physical model eyes. Accuracy is compared for measurements of corneal thickness (d) and ante ... [J. Biomed. Opt. 12, 064023 (2007)] published Tue Dec 18, 2007.
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    3. Great Strides Moved MS Research Forward During 2007

      National Multiple Sclerosis Society Published: December 14, 2007 The year 2007 saw rapid research progress in the fields of science and medicine that impact our understanding of the unpredictable neurological disease multiple sclerosis. Thanks to its generous contributors, the National MS Society was able to invest over $46 million this year into over 440 new and ongoing MS research projects as part of its international effort to prevent, treat and cure MS. Significant advances have been made in
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    4. Comparison of Optic Nerve Head Topography and Visual Field in Eyes with Open-angle and Angle-closure Glaucoma.

      Related Articles Comparison of Optic Nerve Head Topography and Visual Field in Eyes with Open-angle and Angle-closure Glaucoma. Ophthalmology. 2007 Dec 13; Authors: Boland MV, Zhang L, Broman AT, Jampel HD, Quigley HA OBJECTIVE: To compare the optic disc and visual field (VF) alterations in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). DESIGN: Observational case series. PARTICIPANTS: A total of 146 persons (217 eyes), 110 with POAG and 36 with PACG, recruited from a university glaucoma service. METHODS: Each subject underwent visual acuity measurement, applanation tonometry, gonioscopy, slit-lamp examination, dilated optic disc and retinal examination, axial eye length ...
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    5. Chloroquine retinopathy: lipofuscin- and melanin-related fundus autofluorescence, optical coherence tomography and multifocal electroretinography.

      Related Articles Chloroquine retinopathy: lipofuscin- and melanin-related fundus autofluorescence, optical coherence tomography and multifocal electroretinography. Doc Ophthalmol. 2007 Dec 16; Authors: Kellner U, Kellner S, Weinitz S Purpose To evaluate melanin-related near-infrared fundus autofluorescence (NIA, excitation 787 nm, emission > 800 nm), lipofuscin-related fundus autofluorescence (FAF, excitation 488 nm, emission >500 nm), optical coherence tomography (OCT), and multifocal electroretinography (mfERG) in patients with chloroquine (CQ) retinopathy. Methods Two patients with progressed CQ retinopathy underwent clinical examination, ISCEV mfERG evaluation, and FAF and NIA imaging using a confocal scanning laser ophthalmoscope (Heidelberg Retina Angiograph 2) with either a 30 degrees or wide-angle ...
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    6. Birefringence characterization of biological tissue by use of optical coherence tomography.

      Authors: Everett MJ, Schoenenberger K, Colston BW, Da Silva LB An improved polarization-sensitive optical coherence tomography (OCT) system is developed and used to measure birefringence in porcine myocardium tissue and produce two-dimensional birefringence mapping of the tissue. Signal-to-noise issues that cause systematic measurement errors are analyzed to determine the regime in which such measurements are accurate. The advantage of polarization-sensitive OCT systems over standard OCT systems in avoiding image artifacts caused by birefringence is also demonstrated. PMID: 18084468 [PubMed - in process]
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    7. Monoclonal Antibodies: Recent findings in monoclonal antibodies described by researchers from Labbafinejad Medical Center

      Data detailed in 'Dramatic response of choroidal neovascularization associated with choroidal osteoma to the intravitreal injection of bevacizumab (Avastin)' have been presented. In this recent study, researchers in Iran conducted a study "To report the dramatic response of juxtafoveal choroidal neovascularization (CNV) associated with choroidal osteoma to a single intravitreal...
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    8. Synthesized optical coherence tomography for imaging of scattering objects by use of a stepwise frequency-modulated tunable laser diode.

      Opt Lett. 1999 Nov 1;24(21):1502-4 Authors: He Z, Hotate K A technique named synthesized optical coherence tomography (SOCT) has been proposed and developed as an alternative method to the well-known optical coherence tomography for cross-sectional imaging of scattering objects. SOCT is based on the principle of synthesis of an optical coherence function by use of a tunable laser diode. With stepwise frequency modulation of light and synchronous phase modulation, the coherence function is synthesized into a peak at an arbitrary location. The longitudinal scattering distribution of the object under test is thus obtained without a mechanically driven ...
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    9. Optimal interferometer designs for optical coherence tomography.

      Opt Lett. 1999 Nov 1;24(21):1484-6 Authors: Rollins AM, Izatt JA We introduce a family of power-conserving fiber-optic interferometer designs for low-coherence reflectometry that use optical circulators, unbalanced couplers, and (or) balanced heterodyne detection. Simple design equations for optimization of the signal-to-noise ratio of the interferometers are expressed in terms of relevant signal and noise sources and measurable system parameters. We use the equations to evaluate the expected performance of the new configurations compared with that of the standard Michelson interferometer that is commonly used in optical coherence tomography (OCT) systems. The analysis indicates that improved sensitivity is ...
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    10. Corneal Imaging with Anterior Segment Optical Coherence Tomography for Lamellar Keratoplasty Procedures.

      Am J Ophthalmol. 2007 Oct 26; Authors: Lim LS, Aung HT, Aung T, Tan DT PURPOSE: To assess and describe the uses of anterior segment optical coherence tomography (OCT) in the evaluation of the cornea before and after lamellar corneal transplantation procedures. DESIGN: Prospective, noncomparative, observational case series. METHODS: Seven eyes of seven patients undergoing anterior and posterior lamellar corneal transplantation procedures at the Singapore National Eye Centre were included in the study. High-resolution anterior segment OCT scans of the cornea and anterior segment were performed both before and after lamellar transplantation procedures on the cornea with the Visante anterior ...
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    11. Birefringence imaging of human skin by polarization-sensitive spectral interferometric optical coherence tomography.

      Related Articles Birefringence imaging of human skin by polarization-sensitive spectral interferometric optical coherence tomography. Opt Lett. 2002 Oct 15;27(20):1803-5 Authors: Yasuno Y, Makita S, Sutoh Y, Itoh M, Yatagai T We have developed a spectral interferometric optical coherence tomography (OCT) system with polarization sensitivity that is able to measure a two-dimensional tomographic image by means of one-dimensional mechanical scanning. Our system, which has an axial resolution of 32 mum , calculates the distribution of each element of the Müller matrix of a measured object from 16 OCT images. The OCT system successfully reveals the birefringent nature of ...
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    12. Self-referenced Doppler optical coherence tomography.

      Related Articles Self-referenced Doppler optical coherence tomography. Opt Lett. 2002 Dec 2;27(23):2085-7 Authors: Yazdanfar S, Izatt JA Doppler optical coherence tomography (DOCT) allows simultaneous micrometer-scale resolution cross-sectional imaging of tissue structure and blood flow. We demonstrate a fiber-optic polarization-diversity-based differential phase contrast DOCT system as a method to perform self-referenced velocimetry in highly scattering media. Using this strategy, we reduced common-mode interferometer noise to PMID: 18033449 [PubMed - in process]
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    13. Study of an ultrahigh-numerical-aperture fiber continuum generation source for optical coherence tomography.

      Related Articles Study of an ultrahigh-numerical-aperture fiber continuum generation source for optical coherence tomography. Opt Lett. 2002 Nov 15;27(22):2010-2 Authors: Marks DL, Oldenburg AL, Reynolds JJ, Boppart SA The axial resolution of optical coherence tomography images is primarily dependent on the bandwidth of the illumination source. Continuum generation is one way to generate the single-mode, high-bandwidth light needed for point illumination. We present an inexpensive and easy-to-implement augmentation to a Ti:sapphire laser that widens the bandwidth from 20 to over 200 nm with commerically available ultrahigh-numerical-aperture fiber. This technique can provide a readily available broad-bandwidth source ...
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    14. Comparison of the Corneal Thickness as Measured by Visante(R) Anterior Segment OCT Versus Ultrasound Technique.

      [Comparison of the Corneal Thickness as Measured by Visante(R) Anterior Segment OCT Versus Ultrasound Technique.] Klin Monatsbl Augenheilkd. 2007 Nov;224(11):832-836 Authors: Wildner K, Müller M, Dawczynski J, Strobel J BACKGROUND: Pachymetry is important in relation to the intraocular pressure (IOP) and can either be contact measured or non-contact measured. Depending on the corneal thickness it is possible to get false IOP measurements up to +/-5 mmHg. Thus, it is necessary to know the exact corneal thickness. A new non-contact technique for measuring the corneal thickness is available with the Visante(R) anterior segment optical coherence ...
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    15. Macular retinal detachment associated with peripapillary detachment in pathologic myopia.

      Purpose A peripapillary detachment in pathologic myopia (PDPM) appears as a yellowish-orange lesion around the optic disc in highly myopic eyes. We report a case in which a macular retinal detachment (RD) accompanied a PDPM. Method A case report was used in this study. Results The right eye in a 48-year-old man showed a macular RD and a PDPM. Fluorescein fundus angiography showed no dye leakage, suggestive of an optic pit within the optic disc. Optical coherence tomography (OCT) examination revealed that there was a full-thickness tissue defect in the retina overlying PDPM, the vitreous cavity was connected to PDPM ...
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    16. [Solar Retinopathy: Follow-Up Examinations with Optical Coherence Tomography (oct) and Microperimetry.]

      Related Articles [Solar Retinopathy: Follow-Up Examinations with Optical Coherence Tomography (OCT) and Microperimetry.] Klin Monatsbl Augenheilkd. 2007 Nov;224(11):862-866 Authors: Koinzer SO, Treumer F, Elsner H, Roider J BACKGROUND: Solar retinopathy is a phototoxic damage to the central retina. It may cause visual deterioration and a central scotoma with reading difficulties, that usually fade with time. Morphological and functional changes can be very subtle and are often inadequately detected by standard examinations. PATIENTS AND METHODS: The more affected, left eye of a 41-year-old female patient was examinded clinically, by optical coherence tomography (OCT 3) and by MP 1 ...
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    17. State-of-the-art retinal optical coherence tomography.

      OCT functions as a type of optical biopsy, providing information on retinal pathology in situ and in real time, with resolutions approaching that of excisional biopsy and histopathology. The development of ultrabroad-bandwidth and tunable light sources, as well as high-speed Fourier detection techniques, has enabled a significant improvement in ophthalmic optical coherence tomography (OCT) imaging performance. Three-dimensional, ultrahigh-resolution OCT (UHR OCT) can provide information on intraretinal morphology that is not available from any other non-invasive diagnostic. High-speed imaging facilitates the acquisition of three-dimensional data sets (3D-OCT), thus enabling volumetric rendering and the generation of OCT fundus images that precisely and ...
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    18. Visual prognosis and vitreous cytokine levels after arteriovenous sheathotomy in branch retinal vein occlusion associated with macular oedema.

      Purpose: To investigate the relationship between vitreous levels of cytokines, including interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF), and visual prognosis after pars plana vitrectomy (PPV) with arteriovenous sheathotomy in patients with branch retinal vein occlusion (BRVO) associated with macular oedema. Methods: We studied 60 patients with logMAR visual acuity (VA) scores of PMID: 18039346 [PubMed - as supplied by publisher]
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    19. Optical coherence tomography and disease subtype in multiple sclerosis.

      OBJECTIVE: To examine retinal nerve fiber layer (RNFL) thickness, macular volumes (MV), and visual acuity in multiple sclerosis (MS) eyes, with and without history of acute optic neuritis (ON). METHODS: RNFL thickness was measured in 326 MS and 94 control eyes using optical coherence tomography (OCT). MV and vision testing were done in a subset of the cohort. MS subtype was classified as relapsing-remitting (RRMS, n = 135), primary progressive (PPMS, n = 12), and secondary progressive (SPMS, n = 16). RESULTS: MS ON eyes had decreased RNFL thickness (84.2 microm) compared to controls (102.7 microm) (p PMID: 18040015 [PubMed - in ...
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    20. Effect of oral pentoxifylline on cystoid macular edema associated with central retinal vein occlusion.

      Related Articles Effect of oral pentoxifylline on cystoid macular edema associated with central retinal vein occlusion. Retina. 2007 Oct;27(8):1020-5 Authors: Park CH, Scott AW, Fekrat S PURPOSE: To determine whether oral pentoxifylline, a xanthine-derived hemorheologic agent, decreases cystoid macular edema (CME) and improves visual acuity in eyes with a perfused central retinal vein occlusion (CRVO). METHODS: Retrospective chart review of consecutive patients on pentoxifylline (400 mg po TID) for CRVO was performed. Inclusion criteria included CME, pentoxifylline use for at least 1 month, and a follow-up period of at least 4 months. Exclusion criteria included nonperfused or ...
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    21. Rebound of cystoid macular edema with continued use of acetazolamide in patients with retinitis pigmentosa.

      Related Articles Rebound of cystoid macular edema with continued use of acetazolamide in patients with retinitis pigmentosa. Retina. 2007 Oct;27(8):1112-8 Authors: Apushkin MA, Fishman GA, Grover S, Janowicz MJ PURPOSE: To demonstrate the presence of a rebound effect with the use of acetazolamide for the treatment of cystoid macular edema (CME) in patients with retinitis pigmentosa (RP). METHODS: Six patients with RP and cystic-appearing lesions in the macula demonstrated by fluorescein angiography and/or optical coherence tomography (OCT) were treated with an oral form of carbonic anhydrase inhibitor (acetazolamide [500 mg]) as a single daily dose. RESULTS ...
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