1. Articles in category: Ophthalmology

    12049-12072 of 12767 « 1 2 ... 500 501 502 503 504 505 506 ... 530 531 532 »
    1. One-Year Results and Anterior Segment Optical Coherence Tomography Findings of Descemet Stripping Automated Endothelial Keratoplasty Combined With Phacoemulsification

      Objective  To report 1-year results and anterior segment optical coherence tomography findings of Descemet stripping automated endothelial keratoplasty combined with phacoemulsification in patients with cataract and Fuchs endothelial dystrophy. Methods  Twelve eyes of 11 patients with at least 1-year follow-up were retrospectively reviewed. Measured variables included best spectacle-corrected visual acuity, refractive spherical equivalent and predictability, anterior corneal keratometric values, complications, and anterior segment optical coherence tomography findings. Results  The mean follow-up was 14.33 months (range, 12-18 months). The best spectacle-corrected visual acuity was unchanged (8%) or improved (92%) in all eyes compared with the preoperative levels. A mean (SD ...
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    2. Automated Diagnosis of Glaucoma Using Digital Fundus Images

      Abstract  Glaucoma is a disease of the optic nerve caused by the increase in the intraocular pressure of the eye. Glaucoma mainly affects the optic disc by increasing the cup size. It can lead to the blindness if it is not detected and treated in proper time. The detection of glaucoma through Optical Coherence Tomography (OCT) and Heidelberg Retinal Tomography (HRT) is very expensive. This paper presents a novel method for glaucoma detection using digital fundus images. Digital image processing techniques, such as preprocessing, morphological operations and thresholding, are widely used for the automatic detection of optic disc, blood vessels ...
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    3. Applications of anterior segment optical coherence tomography in ophthalmology

      The background, technical characteristics and operation procedures of anterior segment optical coherence tomography (OCT) are introduced. The ophthalmic applications of this technique are summarized. The initial studies showed that anterior segment OCT can be a promising tool for the observation of image and analysis of the cornea, the imaging and biological measuring of the anterior chamber, the observation of image and quantitative evaluation of the anterior chamber angle, the observation of image and assessment of phakic intraocular lenses, the observation of image and evaluation of trabeculectomy blebs as well as the observation of ocular accommodation. PMID: 18683707 [PubMed - in process]
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    4. Macular Holes and Macular Pucker: The Role of Vitreoschsis as Imaged By Optical Coherence Tomography/Scanning Laser Ophthalmoscopy

      Macular Holes and Macular Pucker: The Role of  Vitreoschsis as Imaged By Optical Coherence Tomography/Scanning Laser Ophthalmoscopy
      Purpose The pathogenesis of macular pucker and macular holes is poorly understood. Anomalous posterior vitreous detachment (PVD) and vitreoschisis have been proposed as possible mechanisms. This study used clinical imaging to seek vitreoschisis and study the topographic features of macular pucker and macular holes. Methods Combined optical coherence tomography and scanning laser ophthalmoscopy (OCT/SLO) was performed in 45 eyes with macular hole and 44 eyes with macular pucker. Longitudinal imaging was used to identify vitreoschisis and measure retinal thickness. The topographic features of eyes with macular hole with eccentric macular contraction were compared to 24 eyes with unifocal macular ...
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    5. Quantitative Evaluation of Anterior Segment Parameters in the Era of Imaging

      Quantitative Evaluation of Anterior Segment Parameters in the Era of Imaging
      Purpose To review the parameters for quantitative assessment of the anterior segment and iridocorneal angle and to develop a comprehensive schematic for the evaluation of angle anatomy and pathophysiology by high-resolution imaging. Methods The published literature of the last 15 years was reviewed, analyzed, and organized into a construct for assessment of anterior segment processes. Results Modern anterior segment imaging techniques have allowed us to devise new quantitative parameters to improve the information obtained. Ultrasound biomicroscopy, slit-lamp optical coherence tomography, and anterior segment optical coherence tomography provide high-resolution images for analysis of physiologic and pathologic processes. These include iridocorneal angle ...
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    6. Optical Coherence Tomography Measurements and Analysis Methods in Optical Coherence Tomography Studies of Diabetic Macular Edema

      Objective: To evaluate optical coherence tomography (OCT) measurements and methods of analysis of OCT data in studies of diabetic macular edema (DME). Design Associations of pairs of OCT variables and results of 3 analysis methods using data from 2 studies of DME. Participants Two hundred sixty-three subjects from a study of modified Early Treatment of Diabetic Retinopathy Study (mETDRS) versus modified macular grid (MMG) photocoagulation for DME and 96 subjects from a study of diurnal variation of DME. Methods Correlations were calculated for pairs of OCT variables at baseline and for changes in the variables over time. Distribution of OCT ...
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    7. In vivo measurement of erythrocyte velocity and retinal blood flow using adaptive optics scanning laser ophthalmoscopy

      In vivo measurement of erythrocyte velocity and retinal blood flow using adaptive optics scanning laser ophthalmoscopy
      Zhangyi Zhong, Benno L. Petrig, Xiaofeng Qi, Stephen A. Burns. In vivo measurement of retinal blood flow is obtained by measuring the blood velocity of erythrocytes and lumen diameters of the blood vessels using an adaptive optics scanning laser ophthalmoscope. Erythrocyte velocity is measured by tracking erythrocytes moving across a horizontal scanning line. ... [Opt. Express 16, 12746-12756 (2008)]
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    8. Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography in Non-glaucomatous Taiwanese.

      Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography in Non-glaucomatous Taiwanese. J Formos Med Assoc. 2008 Aug;107(8):627-34 Authors: Peng PH, Lin HS Background/Purpose: Assessment of the peripapillary retinal nerve fiber layer (RNFL) is essential for neuroretinal diseases, especially for early prediction of glaucomatous damage. The purpose of this study was to measure RNFL thickness by Stratus optical coherence tomography (OCT) in normal Taiwanese subjects according to age group. Methods: The thickness of the RNFL around the disc of normal subjects was obtained, after pupil dilation, by means of 3.4 mm diameter fast mode ...
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    9. Clinical Spectrum of Lamellar Macular Defects Including Pseudoholes and Pseudocysts Defined By Optical Coherence Tomography

      Objective: To present the clinical spectrum of lamellar macular defects and describe the different subtypes based on their OCT configuration and visual prognosis. Methods: The retrospective observational case series reviewed OCT scans of 92 eyes with lamellar macular defects. Lamellar macular defects were categorized into subtypes of macular pseudohole (MPH), lamellar macular hole (LMH), and foveal pseudocyst (FP) according to their OCT morphology. The defects were quantitatively characterized in terms of base diameter, depth, central foveal thickness, and examined for the presence of associated epiretinal membranes (ERM). Results: Visual acuity (VA) was significantly correlated with the central foveal thickness and ...
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    10. Aditya Jyot Eye Hospital launches 4th generation OCT machine

      Aditya Jyot Eye Hospital, one of the leading eye hospital and institutes in Mumbai, launched the latest 4th generation Optical Coherence Tomography (OCT) which will combine evaluation of retina, cornea and glaucoma in one. The state of the art Optovue RTvue 100 - 3D fourier domain OCT machine with its unique software capabilities will enable precise and thorough eye evaluation. Union minister Sushil Kumar Shinde and model Aditi Govitrikar inaugurated the new facility at the Aditya Jyot hospital which is the first hospital in Mumbai to launch such a facility. Marking years of dedicated efforts towards eradicating blindness and providing vision ...
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    11. Glaucoma care and clinical profile in Priest Hospital, Thailand.

      Glaucoma care and clinical profile in Priest Hospital, Thailand. J Med Assoc Thai. 2008;91 Suppl 1:S111-8 Authors: Sothornwit N, Jenchitr W, Pongprayoon C OBJECTIVE: To assess the prevalence, mechanism and status of glaucoma, and to investigate the magnitude of visual impairment from glaucoma and its relating factors in Buddhist priest and novices. MATERIAL AND METHOD: Cross-sectional study of 190 patients treated in Glaucoma service, Priest hospital was performed. One hundred thirty seven patients with glaucoma and suspected glaucoma had comprehensive ophthalmic examination included interview on medical and ocular history, visual acuity, applanation tonometry, gonioscopy, optic disc, visual field ...
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    12. Localization of nerve fiber bundles by polarization-sensitive optical coherence tomography.

      Localization of nerve fiber bundles by polarization-sensitive optical coherence tomography. J Neurosci Methods. 2008 Jul 16; Authors: Nakaji H, Kouyama N, Muragaki Y, Kawakami Y, Iseki H Diagnostic modalities that can distinguish brain tumors from eloquent cortices or nerve fiber bundles are important for neurosurgery. For identifying nerve fiber bundles, various techniques such as diffusion tensor imaging and subcortical stimulation mapping have been used. In this article, we propose localization of nerve fiber bundles by polarization-sensitive optical coherence tomography (PS-OCT) for the first time. PS-OCT performs tomographic imaging by measuring the travel distance and the change in polarization of the ...
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    13. Time course of morphologic effects on different retinal compartments after ranibizumab therapy in age-related macular degeneration.

      Time course of morphologic effects on different retinal compartments after ranibizumab therapy in age-related macular degeneration. Ophthalmology. 2008 Aug;115(8):e39-46 Authors: Ahlers C, Golbaz I, Stock G, Fous A, Kolar S, Pruente C, Schmidt-Erfurth U PURPOSE: To analyze the effect of ranibizumab therapy on retinal and subretinal compartments in age-related macular degeneration and to compare the time course of compartment specific effects to visual function. DESIGN: Prospective noncomparative case series. PARTICIPANTS: Fourteen patients with changes in 3 major compartments owing to neovascular age-related macular degeneration. METHODS: Standard treatment with 3 monthly doses of intravitreal ranibizumab was performed. Eyes ...
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    14. Visualization of Sub-Retinal Pigment Epithelium and Sub-Choroidal Neovascularization Morphologies of Exudative Macular Diseases by Optical Coherence Tomography with Long Wavelength Probe.

      Visualization of Sub-Retinal Pigment Epithelium and Sub-Choroidal Neovascularization Morphologies of Exudative Macular Diseases by Optical Coherence Tomography with Long Wavelength Probe. Invest Ophthalmol Vis Sci. 2008 Aug 1; Authors: Yasuno Y, Miura M, Kawana K, Makita S, Sato M, Okamoto F, Yamanari M, Iwasaki T, Yatagai T, Oshika T Purpose: To evaluate the clinical significance of the newly developed long wavelength probe optical coherence tomography (LP-OCT) for the diagnosis of exudative macular diseases. Participants: Fourteen eyes of 13 cases were prospectively involved in this study. The cases included 7 type-I and 5 type-II choroidal neovascularization (CNV) cases associated with age ...
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    15. Reproducibility of Nerve Fiber Layer Thickness Measurements using 3D Fourier-Domain OCT (Topcon 3d-OCT1000).

      Reproducibility of Nerve Fiber Layer Thickness Measurements using 3D Fourier-Domain OCT (Topcon 3d-OCT1000). Invest Ophthalmol Vis Sci. 2008 Aug 1; Authors: Menke MN, Knecht P, Sturm V, Dabov S, Funk J Purpose: Conventional time-domain optical coherence tomography (OCT) has been shown to provide reproducible retinal nerve fiber layer (RNFL) measurements. Recently, high-speed, high-resolution Fourier-domain 3d-OCT has been introduced to improve OCT quality. It can provide 6x6 mm high-density scans to provide RNFL thickness measurements. The purpose of this study was to test the reproducibility of 3d-OCT RNFL thickness measurements in healthy volunteers. Methods: 38 eyes were included into the study ...
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    16. Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis

      BackgroundStudying axonal loss in the retina is a promising biomarker for multiple sclerosis (MS). Our aim was to compare optical coherence tomography (OCT) and Heidelberg retinal tomography (HRT) techniques to measure the thickness of the retinal nerve fiber layer (RNFL) in patients with MS, and to explore the relationship between changes in the RNFL thickness with physical and cognitive disability. We studied 52 patients with MS and 18 proportionally matched controls by performing neurological examination, neuropsychological evaluation using the Brief Repetitive Battery-Neuropsychology and RNFL thickness measurement using OCT and HRT.ResultsWe found that both OCT and HRT could define a ...
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    17. OCT-guided Avastin Retreatment Reduces Number of Injections

      Optical Coherence Tomography (OCT) has been shown to have great success in determining whether or to provide additional treatments of Avastin to patients suffering from the wet form of age related macular degeneration (AMD). A study published in Ophthalmologe on July 19, 2008 reported the success of using OCT as the basis of deciding to provide additional treatments of Avastin. In the study, thirty-two patients were treated with a single injection of Avastin, and were reinjected based on the results of an OCT examination. After just a single injection, 74% of the patients deomonstrated complete retinal fluid absorption, with 44 ...
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    18. High-resolution Fourier-Domain Optical Coherence Tomography and Microperimetric Findings After Macula-off Retinal Detachment Repair

      Objective To evaluate the morphologic changes in the macula of subjects with repaired macula-off retinal detachment (RD) using high-resolution Fourier-domain optical coherence tomography (FD OCT) and to perform functional correlation in a subset of patients using microperimetry (MP-1). Design Prospective observational case series. Participants Seventeen eyes from 17 subjects who had undergone anatomically successful repair for macula-off, rhegmatogenous RD at least 3 months earlier and without visually significant maculopathy on funduscopy. Methods FD OCT with axial and transverse resolution of 4.5 μm and 10 to 15 μm, respectively, was used to obtain rapid serial B-scans of the macula, which ...
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    19. High-resolution Fourier-Domain Optical Coherence Tomography and Microperimetric Findings After Macula-off Retinal Detachment Repair.

      High-resolution Fourier-Domain Optical Coherence Tomography and Microperimetric Findings After Macula-off Retinal Detachment Repair. Ophthalmology. 2008 Jul 30; Authors: Smith AJ, Telander DG, Zawadzki RJ, Choi SS, Morse LS, Werner JS, Park SS OBJECTIVE: To evaluate the morphologic changes in the macula of subjects with repaired macula-off retinal detachment (RD) using high-resolution Fourier-domain optical coherence tomography (FD OCT) and to perform functional correlation in a subset of patients using microperimetry (MP-1). DESIGN: Prospective observational case series. PARTICIPANTS: Seventeen eyes from 17 subjects who had undergone anatomically successful repair for macula-off, rhegmatogenous RD at least 3 months earlier and without visually significant ...
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    20. Relationship between Retinal Nerve Fiber Layer Measurement and Signal Strength in Optical Coherence Tomography

      Purpose To examine the relationship between signal strength and retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (OCT). Design Observational cross-sectional study. Participants Forty normal subjects were recruited. Methods Retinal nerve fiber layer (RNFL) thickness was measured by Stratus OCT (Carl Zeiss Meditec, Dublin, CA). In each eye, the focusing knob was adjusted to obtain 6 images with different signal strengths ranging from 5 to 10. The relationships between signal strength and RNFL thickness were examined using the Spearman correlation coefficient. The differences of RNFL thicknesses were compared with repeated-measures analysis of variance. Main Outcome Measures Retinal ...
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    21. The Role of Abnormal Vitreomacular Adhesion in Age-related Macular Degeneration: Spectral Optical Coherence Tomography and Surgical Results

      Purpose: To assess the incidence of vitreomacular adhesion and traction in age-related macular degeneration (AMD), and to evaluate surgical treatment in a subset of patients with choroidal neovascularization (CNV) nonresponsive to anti-neovascular growth factor (anti-VEGF) treatment.Design: Retrospective observational case-control and interventional case series.Methods: Spectral optical coherence tomography, combined with simultaneous scanning laser ophthalmoscope (Spectral OCT/SLO), was performed in 170 eyes of 94 elderly patients, 61 with exudative AMD, 59 with nonexudative AMD, and 50 control eyes. The presence of hyaloid adhesion to the posterior pole, and vitreomacular traction (VMT) were determined. Five patients with VMT underwent surgical ...
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