1. Articles in category: Ophthalmology

    12049-12072 of 12169 « 1 2 ... 500 501 502 503 504 505 506 507 »
    1. Corneal Imaging with Anterior Segment Optical Coherence Tomography for Lamellar Keratoplasty Procedures

      Ten eyes of eight patients with pathologies involving the corneal stroma and sparing the Descemet membrane (DM) were included in this study conducted at a tertiary care hospital. The indications for DALK included corneal clouding attributable to mucopolysaccharidoses (n = 2), macular corneal dystrophy (n = 5), lattice corneal dystrophy (n = 1), granular corneal dystrophy (n = 1), and stromal scar attributable to infectious keratitis (n = 1). DALK was performed using the big-bubble technique in o
      Read Full Article
    2. Changes in diabetic macular oedema after phacoemulsification surgery

      Purpose To quantitatively examine changes in macular oedema after phacoemulsification surgery in eyes with diabetic retinopathy (DR) and in eyes without DR. Methods Thirty-four eyes with DR and 34 eyes with no DR scheduled for phacoemulsification surgery were recruited. Foveal thickness and macular volume were measured using optical coherence tomography preoperatively and at 3, 6, and 12 months postoperatively. Grade of diabetic macular oedema was also examined. Results Preoperatively, there were no significant differences between groups in foveal thickness and macular volume. The foveal thickness increased by 20.3% in the DR group and by 6.0% in the no ...
      Read Full Article
    3. Optical Coherence Tomography versus Stereoscopic Fundus Photography or Biomicroscopy for Diagnosing Diabetic Macular Edema: A Systematic Review

      PURPOSE. To review systematically the sensitivity and specificity of optical coherence tomography (OCT) for diagnosing macular edema attributable to diabetic retinopathy compared with well-established gold standard tests such as fundus stereophotography or contact and noncontact fundus biomicroscopy. METHODS. Medline and Embase were searched electronically and six major ophthalmic journals from 1998 to 2006 were hand searched. Two reviewers independently assessed trial searches, studied quality with the QUADAS (Quality Assessment of Diagnostic Accuracy Studies) checklist, and extracted data. The target disease was clinically significant macular edema (CSME) according to Early Treatment of Diabetic Retinopathy Study (ETDRS) criteria. A bivariate model was ...

      Read Full Article
    4. A Comparison of Macular Structure Imaged by Optical Coherence Tomography in Preterm and Full-Term Children

      purpose. Macular anatomic abnormalities were examined by optical coherence tomography (OCT) imaging in premature children and compared with those of full-term children. methods. In a prospective case–control study, premature patients 7 to 14 years of age were divided into three groups (group I, laser-treated retinopathy of prematurity [ROP]; group II, spontaneously regressed ROP; group III, no ROP), and age-matched children (group IV). All the eligible 74 eyes had normal-appearing posterior pole, myopia ≤3 D, and best corrected visual acuity 1.0. When both eyes of a subject were eligible for the study, one eye was randomly selected (10 eyes ...
      Read Full Article
    5. Optical Coherence Tomography for Multiple Sclerosis

      * A group of investigators from Johns Hopkins studied 40 multiple sclerosis (MS) patients with optical coherence tomography (OCT) of the eye (see flashbacks below about the technology), and found that this technique offers a potentially new, cost-effecti... ... Medgadget, Thursday, October 18, 2007 © 2007 SpaceRef Interactive Inc. All rights reserved
      Read Full Article
    6. Retreatment of full-thickness macular hole: predictive value of optical coherence tomography

      Aim: To determine whether the efficacy of re-operation for idiopathic full-thickness macular hole (FTMH) remaining open after initial surgery with internal limiting membrane (ILM) peeling is correlated with macular hole configuration as determined by optical coherence tomography (OCT), macular hole size, macular hole duration before the first operation, or type of tamponade (gas or silicone oil). Methods: A retrospective consecutive interventional case series of 28 patients (28 eyes) with a persisting macular hole after vitrectomy, ILM peel, and gas tamponade. 28 patients underwent repeat surgery involving vitrectomy and gas (n = 15) or silicone oil tamponade (n = 12) or no tamponade ...
      Read Full Article
      Mentions: Carsten Framme
    7. Changes in anterior segment morphology in response to illumination and after laser iridotomy in Asian eyes: an anterior segment OCT study

      Aim: Using the anterior segment optical coherence tomography (AS-OCT) to quantify changes in anterior segment morphology going from light to dark and following laser iridotomy (LI). Methods: Prospective observational study. 17 consecutive subjects without peripheral anterior synechiae undergoing LI were evaluated using gonioscopy and AS-OCT. Angle configuration including angle opening distance (AOD) at 500 microns anterior to the scleral spur, AOD500, trabecular-iris space area up to 750 microns from the scleral spur, TISA750 and the increase in angle opening going from dark to light conditions was determined. Results: Both mean AOD500 and TISA750 increased nearly threefold going from dark to ...

      Read Full Article
    8. Repeatability and reproducibility of anterior chamber angle measurement with anterior segment optical coherence tomography

      Aim: To evaluate the repeatability and reproducibility of anterior chamber angle measurement obtained by anterior segment optical coherence tomography. Methods: Twenty-five normal subjects were invited for anterior chamber angle imaging with an anterior segment optical coherence tomography (OCT) on one randomly selected eye in three separate visits within a week. Each eye was imaged three times under room light (light intensity = 368 lux) and three times in the dark during the first visit. In the subsequent visits, each eye was imaged once in the light and once in the dark. The angle opening distance (AOD 500) and the trabecular–iris ...
      Read Full Article
    9. Tear dynamics measured with optical coherence tomography

      A system and method are provided for measuring the thickness of a tear film layer and the heights of tear menisci around upper and lower eyelids of an eye. A plurality of images are acquired between consecutive blinks the eye using optical coherence tomography (OCT). The images depict the tear film layer and tear menisci as distinct from the cornea of the eye. In an embodiment, a plurality of reflectivity profiles from an OCT image are aligned and averaged. The difference between a first peak and a second peak of the average reflectivity profile is measured to determine the thickness ...
      Read Full Article
    10. High efficiency low coherence interferometry

      In accordance with the present invention, embodiments of interferometers are presented that improves both the polarization dependency problem and helps prevents light from being reflected back into the light source, among other things. Interferometer embodiments can include an isolator coupled to a light source and polarization dependent optics coupled with the isolator to provide light to a reference arm and a sample arm, wherein reflected light provided to optical detectors is such that a polarization independent optical signal can be formed in an optical signal processor coupled to the optical detectors, and the isolator blocks reflected light from the reference ...
      Read Full Article
      Mentions: Optovue Jay Wei
    11. Comparison of macular hole size measured by optical coherence tomography, digital photography, and clinical examination

      Aim To report on the agreement of macular hole size as measured using optical coherence tomography (OCT), Topcon digital photography, and surgeon estimate on clinical examination. Methods Observational cohort series of patients who underwent macular hole surgery over an 18-month period. Patients had OCT scan and digital fundus photographs preoperatively. At operation the surgeon estimated the size of macular hole. The agreement between methods was assessed using the technique described by Bland and Altman. Results There was good repeatability of photographic and OCT assessment and no evidence of systematic bias between repeated macular hole measurement by digital photography (P=0 ...
      Read Full Article
    12. Medical device and methods of use for glaucoma treatment

      The invention relates generally medical devices and methods for the treatment of glaucoma in an animal eye and, more particularly, to medical devices and methods for treating tissue of the trabecular meshwork and/or Schlemm's canal of the eye to restore or rejuvenate a portion or all of the normal physiological function of directing aqueous outflow for maintaining a normal intraocular pressure in the eye.
      Read Full Article
    13. Polypoidal choroidal vasculopathy examined with en face optical coherence tomography

      Background: To study the morphologic features of polypoidal choroidal vasculopathy (PCV) with the use of en face optical coherence tomography (OCT). Methods: We reviewed retrospectively 57 eyes of 57 patients with PCV. The macular region was examined with OCT en face planes scanned at different sequential depths, following which detailed scanning was performed of arbitrarily selected longitudinal planes. Results: In 48 of the cases (84.2%), en face OCT allowed us to detect round protrusions of the retinal pigment epithelium (RPE) that corresponded to the polypoidal lesions seen on indocyanine green angiography (ICGA); the branching vascular networks seen on ICGA ...
      Read Full Article
    14. Optical Coherence Tomography Findings in Persistent Diabetic Macular Edema: The Vitreomacular Interface

      Retina practice. Fifty-two normal eyes of 48 patients and 100 eyes of 80 patients with DME. We measured retinal thickness for nine zones and total macular volume using the 3.5-mm display of an optical coherence tomograph (OCT). We determined the normal ranges of values for zones, and then normal ranges of values for the difference in thickness between each pair of zones, termed comparisons. Frequencies of increased zonal thickness, increased total macular volume, and abnormalities in zonal compa
      Read Full Article
    15. Optical coherence tomography characteristics of full-thickness traumatic macular holes

      Purpose The objective of this paper is to describe the optical coherence tomography (OCT) characteristics of patients with full-thickness traumatic macular hole (TMH) and to correlate them with biomicroscopy findings. Methods Twelve eyes of ten consecutive patients with full-thickness TMH participated in this observational retrospective multicentre study. Patients underwent biomicroscopic fundus examination, colour fundus photography, and OCT. Results Traumatic macular hole was documented with OCT in five women and five men. Mean (range) time between trauma and macular hole (MH) diagnosis was 8.1 (1–24) months. The shape of TMHs was round in 11 (91.7%) eyes. The posterior ...
      Read Full Article
    16. Evaluation of potential image acquisition pitfalls during optical coherence tomography and their influence on retinal image segmentation

      The development of improved segmentation algorithms for more consistently accurate detection of retinal boundaries is a potentially useful solution to the limitations of existing optical coherence tomography (OCT) software. We modeled artifacts related to operator errors that may normally occur during OCT imaging and evaluated their influence on segmentation results using a novel segmentation algorithm. These artifacts included: defocusing, depolarization, decentration, and a combination of defocusing and depolarization. Mean relative reflectance and average thickness of the automatically extracted intraretinal layers was then measured. Our results show that defocusing and depolarization errors together have the greatest altering effect on all measurements ...
      Read Full Article
    17. Retinal nerve fibre layer imaging compared with histological measurements in a human eye

      Purpose A feasibility study comparing retinal nerve fibre layer (RNFL) thickness values obtained with imaging devices against RNFL thickness measurements obtained histologically in a human eye. Design A single patient scheduled for orbital exenteration, who still possessed a healthy functioning eye. Methods Before surgery, the eye was imaged using optical coherence tomography (OCT) and scanning laser polarimetry (SLP). After orbital exenteration, the globe was sectioned, and 100 equidistant RNFL thickness measurements were obtained for each of four concentric rings centred on the optic disc, with diameters of 3.0, 3.5, 4.0, and 4.5 mm. Results RNFL thickness ...

      Read Full Article
    18. Peripapillary intrachoroidal cavitation in high myopia: reappraisal

      Purpose To evaluate optical coherence tomography (OCT) and clinical findings of a peripapillary lesion in high myopia recently named peripapillary detachment in pathologic myopia (PDPM) or intrachoroidal cavitation. Methods Observational case report by chart review, analysis of colour fundus photography, fluorescein angiography, and OCT in 16 eyes of 12 patients with myopic degeneration and the presence of a slightly elevated, patchy peripapillary, yellow-orange lesion on the fundus. Results Patients were mean age 53.110.7 years, with a spherical-equivalent refractive error of -10.993.33 D and mean axial length of 27.341.44 mm. The mean best-corrected visual acuity ...
      Read Full Article
    19. Method and apparatus for screening for retinopathy

      A method of screening for retinal disease including directing a first light at a first portion of the retina, directing a second light at a second portion of the retina, measuring a first pupillary response of the eye as a result of the first light and a second pupillary response as a result of the second light, and generating an indication of a severity level of the retinal disease using the first pupillary response and the second pupillary response. Also, an apparatus that implements this method including a light source for directing a first light at a first retinal portion ...
      Read Full Article
    20. Enhanced optical coherence patterns of diabetic macular oedema and their correlation with the pathophysiology

      Enhanced optical coherence patterns of diabetic macular oedema and their correlation with the pathophysiology
      Purpose: To describe different patterns of diabetic macular oedema (DMO) using a computerized alignment and averaging of sequences in optical coherence tomography (OCT) B-scans and to show the correlation of these patterns with the pathophysiology of the condition. Methods: We carried out a prospective, uncontrolled study, including 46 human subjects with untreated DMO. Enhanced OCT images were produced. We correlated different OCT patterns of DMO with ETDRS visual acuity and with the thickness of the central 1-mm of the macula. We also correlated these patterns with theories of the pathophysiology of DMO. Results: Enhanced OCT images enabled us to examine ...
      Read Full Article
    21. Technical Note: Method for estimating volume of subretinal fluid in cases of localized retinal detachment by OCT ophthalmoscopy

      The volume of the subretinal fluid can be used to assess the condition of different types of retinal and macular disorders. The purpose of this report is to introduce a method to measure the volume of the subretinal fluid with the images of the optical coherence tomography (OCT) Ophthalmoscope in three cases of central serous chorioretinopathy and one case of retinal pigment epithelial detachment. We used the topography-mode program of the OCT Ophthalmoscope and measured the average height of the retinal detachment. By multiplying the size of the area of the retinal detachment and the average height of the retinal ...
      Read Full Article
    22. Enzymatic vitreolysis with recombinant microplasminogen and tissue plasminogen activator

      Purpose To generate microplasmin (Plm) using recombinant microplasminogen (Plg) and recombinant tissue plasminogen activator (rt-PA) before intravitreous injection and to investigate the efficacy of Plm in inducing posterior vitreous detachment (PVD). Methods Forty-eight female or male New Zealand white rabbits were randomized into three groups. Recombinant human Plg was incubated with rt-PA with a 200:1 molar ratio at 37°C for 40 min. The right eyes of groups 1, 2, and 3, were injected with 0.5, 1.0, and 1.5 U Plm in 0.1 ml respectively, and 0.1 ml balanced salt solution (BSS) was injected ...

      Read Full Article
      Mentions: Fudan University
    12049-12072 of 12169 « 1 2 ... 500 501 502 503 504 505 506 507 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (4 articles) Università Vita-Salute San Raffaele
    2. (3 articles) Singapore Eye Research Institute
    3. (2 articles) Center for Ophthalmic Optics and Lasers
    4. (2 articles) Johns Hopkins University
    5. (2 articles) UC Davis
    6. (2 articles) Oregon Health & Science University
    7. (2 articles) Duke University
    8. (2 articles) Northwestern University
    9. (2 articles) University College London
    10. (2 articles) Cleveland Clinic
    11. (2 articles) Medical University of Vienna
    12. (2 articles) University of Miami
  4. People in the News

    1. (3 articles) Robert J. Zawadzki
    2. (2 articles) Ravi S. Jonnal
    3. (2 articles) Steven T. Bailey
    4. (2 articles) Pearse A. Keane
    5. (2 articles) Yali Jia
    6. (2 articles) Tin Aung
    7. (2 articles) David Huang
    8. (2 articles) Mehdi Azimipour
    9. (2 articles) Giuseppe Querques
    10. (2 articles) Francesco Bandello
    11. (2 articles) John S. Werner
    12. (1 articles) Roman V. Kuranov
  5. OCT Companies in the News

    1. (4 articles) Topcon Medical Systems
    2. (4 articles) Carl Zeiss Meditec
    3. (2 articles) Optovue
    4. (2 articles) Specsavers
    5. (1 articles) Tomey Corporation
    6. (1 articles) Opticent Health
    7. (1 articles) Canon Medical Systems
    8. (1 articles) Bioptigen