1. Articles in category: Ophthalmology

    11737-11760 of 12085 « 1 2 ... 487 488 489 490 491 492 493 ... 502 503 504 »
    1. Impact of diabetic retinopathy on quantitative retinal nerve fiber layer measurement and glaucoma screening.

      Related Articles Impact of diabetic retinopathy on quantitative retinal nerve fiber layer measurement and glaucoma screening. Invest Ophthalmol Vis Sci. 2008 Feb;49(2):687-92 Authors: Takahashi H, Chihara E PURPOSE: To investigate the impact of diabetic retinopathy on quantitative retinal nerve fiber layer (RNFL) assessment and diagnostic power for glaucoma by scanning laser polarimetry (GDx-VCC) and optical coherence tomography (StratusOCT). METHODS: The individual RNFL parameters of GDx and OCT were obtained for 170 eyes (one eye from each of 170 subjects [45 healthy, 47 glaucoma, 40 diabetes, and 38 glaucoma with diabetes]) and were compared among the four groups ...
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    2. Diagnosis of macular pseudoholes and lamellar macular holes: is optical coherence tomography the gold standard?

      Aims: To assess fundus autofluorescence (AF) for better differential diagnosis of macular pseudoholes (MPH) and lamellar macular holes (LMH) evaluated with optical coherence tomography (OCT) as the gold standard. Methods: We reviewed the files of 50 eyes of 46 consecutive patients who were diagnosed by OCT as having a foveal defect with residual retinal tissue at the bottom. Retinal thickness was measured at the foveal center and 750 µm temporally and nasally to differentiate further MPH and LMH. The corresponding corrected AF images were then evaluated. Eyes with either macular pucker or stage 1a impending macular hole served as controls ...
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      Mentions: Mario Cigada
    3. Structural and functional imaging by Fourier domain Optical Coherence Tomography

      Dr. Maciej Wojtkowski Nicolaus Copernicus University Grudziadzka 5 87100 Torun Poland http://www.fizyka.umk.pl/en/phys/index.html Thirty-two year old Polish citizen Maciej Wojtkowski is currently an assistant professor at the Institute of Physics of Nicolaus Copernicus University in Poland.  This position follows a number of research visits and exchanges with the Universities of Vienna, Kent and MIT. Dr. Wojtkowski also has experience in managing and participating in projects funded by the Polis
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    4. Association of retinal nerve fibre layer thickness measured by confocal scanning laser ophthalmoscopy and optical coherence tomography with disc size and axial length.

      Related Articles Association of retinal nerve fibre layer thickness measured by confocal scanning laser ophthalmoscopy and optical coherence tomography with disc size and axial length. Br J Ophthalmol. 2008 Feb;92(2):186-90 Authors: Nagai-Kusuhara A, Nakamura M, Fujioka M, Tatsumi Y, Negi A AIMS: To investigate the influence of age, disc size and axial length on the retinal nerve fibre layer (RNFL) thickness measurements of Heidelberg Retina Tomograph (HRT) and optical coherence tomography (OCT). METHODS: A total of 162 eyes of 162 Japanese normal subjects aged between 20 and 83 were enrolled in this study. The disc area and ...
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    5. Multiple Sclerosis: New multiple sclerosis data have been reported by researchers at University of Houston, College of Optometry

      A new study, 'The relationship between visual field and retinal nerve fiber layer measurements in patients with multiple sclerosis,' is now available. In this recent report, researchers in the United States conducted a study "To investigate the relationship between visual function, measured by standard automated perimetry (SAP), and retinal nerve fiber layer (RNFL) thickness,...
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    6. Impact of Diabetic Retinopathy on Quantitative Retinal Nerve Fiber Layer Measurement and Glaucoma Screening

      purpose. To investigate the impact of diabetic retinopathy on quantitative retinal nerve fiber layer (RNFL) assessment and diagnostic power for glaucoma by scanning laser polarimetry (GDx-VCC) and optical coherence tomography (StratusOCT). methods. The individual RNFL parameters of GDx and OCT were obtained for 170 eyes (one eye from each of 170 subjects [45 healthy, 47 glaucoma, 40 diabetes, and 38 glaucoma with diabetes]) and were compared among the four groups. Diabetic eyes had mild to moderate nonproliferative diabetic retinopathy (NPDR) without maculopathy. In glaucomatous eyes with or without diabetes, the ability to discriminate glaucoma was assessed by the areas under ...
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    7. Association of retinal nerve fibre layer thickness measured by confocal scanning laser ophthalmoscopy and optical coherence tomography with disc size and axial length

      Aims: To investigate the influence of age, disc size and axial length on the retinal nerve fibre layer (RNFL) thickness measurements of Heidelberg Retina Tomograph (HRT) and optical coherence tomography (OCT). Methods: A total of 162 eyes of 162 Japanese normal subjects aged between 20 and 83 were enrolled in this study. The disc area and mean RNFL thickness were measured with HRT. The disc area was also measured using the fast optic nerve scan protocol, and the average RNFL thickness was measured using the fast RNFL thickness scan mode with Stratus OCT. The correlations of age, disc area and ...
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    8. Automatic segmentation in three-dimensional analysis of fibrovascular pigmentepithelial detachment using high-definition optical coherence tomography

      Background/aims:A limited number of scans compromise conventional optical coherence tomography (OCT) to track chorioretinal disease in its full extension. Failures in edge-detection algorithms falsify the results of retinal mapping even further. High-definition-OCT (HD-OCT) is based on raster scanning and was used to visualise the localisation and volume of intra- and sub-pigment-epithelial (RPE) changes in fibrovascular pigment epithelial detachments (fPED). Two different scanning patterns were evaluated.Methods:22 eyes with fPED were imaged using a frequency-domain, high-speed prototype of the CirrusTM HD-OCT. The axial resolution was 6 µm, and the scanning speed was 25 kA scans/s. Two different ...

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    9. Value of polarisation-sensitive optical coherence tomography in diseases affecting the retinal pigment epithelium

      Objectives:To evaluate pathological changes of retinal pigment epithelium (RPE) by polarisation-sensitive optical coherence tomography (PS-OCT).Methods:Forty-four eyes (22 patients) with significant pathologies of the RPE were evaluated using PS-OCT. A transversal scanning time domain OCT system was used for two-dimensional cross-sectional imaging of retinal polarisation properties.Results:The RPE scrambles the polarisation state of backscattered light (ie, acts as a depolarising layer), while the polarisation state of transmitted light is maintained. In patients with RPE pathologies irregularity, elevation, thickening or absence of the RPE is readily visualised by exploiting the depolarisation information. Polarisation scrambling in the sensory retina ...

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    10. The effect of acute hyperglycemia on retinal thickness and ocular refraction in healthy subjects.

      The effect of acute hyperglycemia on retinal thickness and ocular refraction in healthy subjects. Graefes Arch Clin Exp Ophthalmol. 2008 Jan 25; Authors: Wiemer NG, Eekhoff EM, Simsek S, Heine RJ, Ringens PJ, Polak BC, Dubbelman M PURPOSE: To quantify the retinal thickness and the refractive error of the healthy human eye during hyperglycemia by means of optical coherence tomography (OCT) and Hartmann-Shack aberrometry. METHODS: Hyperglycemia was induced in five healthy subjects who were given a standard oral glucose tolerance test (OGTT) after a subcutaneous injection of somatostatin. Main outcome parameters were the central, pericentral and peripheral thickness of the ...
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    11. Longitudinal analysis of retinal changes after branch retinal artery occlusion using optical coherence tomography.

      Related Articles Longitudinal analysis of retinal changes after branch retinal artery occlusion using optical coherence tomography. Optometry. 2008 Feb;79(2):85-9 Authors: Asefzadeh B, Ninyo K BACKGROUND: Branch retinal artery occlusion (BRAO) causes inner retinal ischemia leading to permanent inner retinal dysfunction and visual field loss in affected retinal sectors. Optical coherence tomography (OCT) offers a novel way to evaluate in vivo retinal morphologic changes in BRAO in both acute and longitudinal phases. This case report describes OCT findings in BRAO at acute presentation and at follow-up, including the longitudinal evaluation of retinal and peripapillary retinal nerve fiber layer ...
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    12. Imaging Implanted Keratoprostheses With Anterior-Segment Optical Coherence Tomography and Ultrasound Biomicroscopy.

      Related Articles Imaging Implanted Keratoprostheses With Anterior-Segment Optical Coherence Tomography and Ultrasound Biomicroscopy. Cornea. 2008 Feb;27(2):180-188 Authors: Garcia JP, de la Cruz J, Rosen RB, Buxton DF PURPOSE:: To describe the anterior ocular segment findings of eyes with implanted Boston type 1 keratoprostheses (KPro) in vivo by using anterior-segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM). METHODS:: A retrospective, comparative study was made of patients with implanted KPros who were examined with AS-OCT (AC Cornea OCT) and UBM (OTI Scan 35-50MHz Ultrasound). RESULTS:: One pseudophakic and 1 aphakic eye were included in the study. Cross-sectional AS-OCT ...
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    13. Monitoring mouse retinal degeneration with high-resolution spectral-domain optical coherence tomography

      Progression of retinal degeneration in a mouse model was studied in vivo with high-resolution spectral-domain optical coherence tomography (SD-OCT). Imaging in 3D with high depth resolution (<3 μm), SD-OCT resolved all the major layers of the retina of control C57BL/6J mice. Images of transgenic mice having a null mutation of the rhodopsin gene revealed the anatomical consequences of retinal degeneration: thinning of the outer retina, including the outer plexiform layer (OPL), outer nuclear layer (ONL), and inner and outer segments (IS/OS). We monitored the progression of retinal degeneration in rd1 mice (C3H/HeJ) by periodically imaging the same ...
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    14. Application of optical coherence tomography in non-invasive characterization of skin vascular lesions

      Optical coherence tomography (OCT) is a new non-invasive approach for real-time in vivo tissue characterization. A promising use of OCT can be the assessment of the architecture of lesions with some degree of inhomogeneities, such as vascular lesions. Knowledge of the size and depth of the vascular structures can be useful for the diagnosis and for choosing the best treatment.
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    15. The Stress on the Anterior Lens Surface During Human in vivo Accommodation.

      Related Articles The Stress on the Anterior Lens Surface During Human in vivo Accommodation. Br J Ophthalmol. 2008 Jan 22; Authors: Schachar RA, Koivula A Purpose: To determine the qualitative change in stress on the lens capsule during in vivo human accommodation. Methods: Nine subjects [mean age: 30 years, range: 25-38 years] were studied, each of whom had undergone a phakic refractive intraocular lens (PRL) surgical procedure. The change, during accommodation, of stress on the surface of the anterior lens capsule (ALS) was determined by employing high-resolution anterior segment optical coherence tomography (OCT). This was done by comparing the ratio ...
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    16. Intravitreal avastin for macular edmema secondary to retinal vein occlusion - a prospective study.

      Related Articles Intravitreal avastin for macular edmema secondary to retinal vein occlusion - a prospective study. Br J Ophthalmol. 2008 Jan 22; Authors: Kriechbaum K, Michels S, Prager F, Georgopoulos M, Funk M, Geitzenauer W, Schmidt-Erfurth U Abstract OBJECTIVE: To evaluate efficacy and safety of intravitreal bevacizumab (Avastin) in eyes with macular edema secondary to central (CRVO) or branch retinal vein occlusion (BRVO). METHODS: Twenty-eight consecutive patients (28 patients, 29 eyes, 8 CRVO, 21 BRVO) were enrolled in the study. Three intravitreal injections of 1 mg bevacizumab (0.04 ml) were administered at 4 week intervals; further retreatment was based on ...
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    17. Correlation between intraretinal changes in diabetic macular oedema seen in fluorescein angiography and optical coherence tomography

      Abstract.Purpose: To study the relationship between intraretinal optical coherence tomography (OCT) and fluorescein angiography (FA) findings in eyes with diabetic macular oedema (DMO).Methods: We carried out a retrospective observational case series. ...

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    11737-11760 of 12085 « 1 2 ... 487 488 489 490 491 492 493 ... 502 503 504 »
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