1. Articles in category: Ophthalmology

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    1. Change of foveal and perifoveal thickness measured by OCT after phacoemulsification and IOL implantation

      Purpose Cataract surgery is known to elicit postoperative macular oedema owing to its traumatic effect. The aim of the study was to measure the foveal and perifoveal thickness of the retina after uneventful phacoemulsification and posterior chamber intraocular lens (PC-IOL) implantation. Methods Retinal thickness values of the foveal and perifoveal (fovea+3.0 mm, fovea+6.0 mm) sectors and the minimum values were measured in a prospective study using optical coherence tomography (OCT) in 71 eyes of 71 patients (34 men, 37 women, mean age: 68.8 years) who underwent cataract surgery. Phacoemulsification and 'in the bag' implantation of ...
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    2. Optical frequency domain imaging of human retina and choroid (Thesis)

      Optical frequency domain imaging of human retina and choroid (Thesis)
      Optical coherence tomography (OCT) has emerged as a practical noninvasive technology for imaging the microstructure of the human eye in vivo. Using optical interferometry to spatially-resolve backreflections from within tissue, this high-resolution technique provides cross-sectional images of the anterior and posterior eye segments that had previously only been possible with histology. Current commercially-available OCT systems suffer limitations in speed and sensitivity, preventing them from effective screening of the retina and having a larger impact on the clinical environment. While other technological advances have addressed this problem, they are inadequate for imaging the choroid, which can be useful for evaluating choroidal ...
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    3. Optical Coherence Tomography For The Screening of Donor Corneas and Examination of the Retinal Nerve Fiber Directional Reflectance (Thesis)

      Optical Coherence Tomography For The Screening of Donor Corneas and Examination of the Retinal Nerve Fiber Directional Reflectance (Thesis)
      Optical coherence tomography (OCT) is a high resolution, non-invasive imaging technology that employs light to create detailed images of the body. In medicine, OCT is most widely used in ophthalmology to create high resolution images of the cornea and the retina. The group index of cornea, rather than phase refractive index, is required for thickness calculations with optical coherence tomography (OCT). Recent advances with high speed OCT at 1.3 m make index measurement at this wavelength of great interest. Group indices of 3 human eye bank corneas were measured in vitro using optical low-coherence reflectometry. Measurements were made in ...
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    4. Implant with pressure sensor for glaucoma treatment

      A trabecular shunt and methods for treating glaucoma are disclosed. One of the methods comprises transporting fluid from the anterior chamber of an eye to Schlemm's canal through an implant, the implant extending between the anterior chamber and Schlemm's canal; sensing an intraocular pressure using a sensor incorporated into the implant; and transmitting a signal indicative of the sensed pressure to an external receiver.
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    5. Automated detection of retinal layer structures on optical coherence tomography images

      Automated detection of retinal layer structures on optical coherence tomography images
      Segmentation of retinal layers from OCT images is fundamental to diagnose the progress of retinal diseases. In this study we show that the retinal layers can be automatically and/or interactively located with good accuracy with the aid of local coherence information of the retinal structure. OCT images are processed using the ideas of texture analysis by means of the structure tensor combined with complex diffusion filtering. Experimental results indicate that our proposed novel approach has good performance in speckle noise removal, enhancement and segmentation of the various cellular layers of the retina using the STRATUSOCTTM system.
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    6. Novel Diagnostics With Optical Coherence Tomography: Retinal Imaging

      The purpose of this research is to evaluate optical coherence tomography (OCT) and FDA approved device used to image diseases of the eye. The ultra-high resolution OCT is a non-significant risk device used in this study. Optical Coherence Tomography may be useful for early diagnosis and monitoring of different types of eye diseases.
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    7. Method and apparatus for improving vision and the resolution of retinal images

      A method of and apparatus for improving vision and the resolution of retinal images is described in which a point source produced on the retina of a living eye by a laser beam is reflected from the retina and received at a lenslet array of a Hartmann-Shack wavefront sensor such that each of the lenslets in the lenslet array forms an aerial image of the retinal point source on a CCD camera located adjacent to the lenslet array. The output signal from the CCD camera is acquired by a computer which processes the signal and produces a correction signal which ...

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    8. System and method for evaluating a secondary Lasik treatment

      A method and system are disclosed for evaluating the safety of a prospective secondary LASIK treatment to correct a person's vision. The difficulties with making an accurate, direct measurement of corneal thickness of a cornea having a pre-existing keratectomy are overcome by using pre-LASIK topography and pachymetry measurements, and per- and post-LASIK wavefront measurements to determine post-LASIK corneal thickness, and thus the suitability and safety of a prospective secondary LASIK procedure. A system embodiment includes diagnostic and computing platforms for generating and analyzing data, and a device readable medium for storing and transferring an instruction to a laser ablation ...
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      Mentions: Bausch & Lomb
    9. Device and method for monitoring aqueous flow within the eye

      The present invention provides a device and method for monitoring the flow of aqueous humor within the eye. The invention provides that the aqueous flow rate and/or pattern within the anatomical structures of the eye can be determined by monitoring a traceable component. Such determination provides diagnostic indications of the degree and location of ocular disease associated with aqueous outflow, such as glaucoma, and can further provide post-treatment indications of effectiveness.
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    10. Optical multiplex short coherence interferometry on the eye

      The invention is directed to the detection and imaging of the internal geometry of the eye, particularly of the important components for imaging in the eye such as the cornea, lens, vitreous body and retinal surface, by multichannel short coherence interferometry. A method and arrangement for obtaining topograms and tomograms of the eye structure by many simultaneously recorded interferometric depth scans through transversely adjacent points in the pupil using spatially coherent or spatially partially coherent light sources. The depth scan is carried out by changing the optical length of the interferometer measurement arm by means of a retroreflector. By continuously ...
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    11. Heidelberg Engineering Adds OCT Product Line

      Heidelberg Engineering Adds OCT Product Line

      DOSSENHEIM, Germany--June 6, 2005--Heidelberg Engineering GmbH announced today the purchase of assets of the company 4optics AG, Lubeck, Germany. The transaction adds optical coherence tomography (OCT) technology to its ophthalmic product offering. "Heidelberg Engineering has a wide range of expertise in laser scanning technology for diagnostic eye care. With this move, we are adding a well-qualified scientific team and additional products to our R&D pipeline," noted Dr. Gerhard Zinser, managing director and head of R&D for Heidelberg Engineering. "We now have command of the two most important technological innovations in diagnostic eye care.” The company will take over ...

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    12. Enhanced visualization of retinal pathologies with ultrahigh resolution optical coherence tomography (Thesis)

      Enhanced visualization of retinal pathologies with ultrahigh resolution optical coherence tomography (Thesis)
      Current clinical practice calls for the development of techniques to diagnose diseases in its early stages, when treatment is most effective and significant irreversible damage can either be prevented or delayed. Optical coherence tomography (OCT) is an emerging medical diagnostic technology being investigated for applications in a number of medical fields including ophthalmology, cardiology, and gastroenterology. OCT is analogous to ultrasound except that it uses light waves rather than sound waves. OCT can achieve a much higher resolution than ultrasound in measuring the underlying tissue microstructures. Another advantage of OCT is that it can achieve imaging in a non-contact and ...
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    13. Optical coherence tomography for retinal imaging (Thesis)

      Optical coherence tomography for retinal imaging (Thesis)
      In this thesis, two new imaging modalities are proposed for the early detection of glaucoma. Both modalities are based on optical coherence tomography, a technology that uses low-coherence light to create two-dimensional images of the retina. Depth scans are made as reflections are detected as a function of path length difference by rapidly changing the reference arm length of an interferometer. The sensitive coherence window that is created rejects light returning from other depths.
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    14. A Test Eye for Wavefront Eye Refractors

      A Test Eye for Wavefront Eye Refractors
      PURPOSE A multi-site study was conducted to test feasibility of a modified automatic refractor style test eye as a test device for wavefront refractors of various types and to determine whether a) they could be measured and b) when measurements could be made, to see if they were similar. This study did not attempt to assess which instrument most accurately measures the aberrations of the test eye or human eye. METHODS Three automatic refractor style test eyes were modified for use as test devices for wavefront refractors. One had a simple spherical front surface, and two had additional aberrations added ...
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    15. Atlas of Optical Coherence Tomography of Macular Diseases (Book)

      Atlas of Optical Coherence Tomography of Macular Diseases (Book)
      In real time, optical coherence tomography (OCT) provides high-resolution cross-sectional images of the macula very similar to those obtained by in vivo histopathological sections. OCT represents a major advance in the diagnostics of retinal disease and has found rapid acceptance among retinal specialists worldwide. OCT is not a substitute for a thorough clinical examination, fundus imaging or various angiographic techniques, but a superb adjunctive tool for probing the mysteries of retinal disease. Throughout this highly illustrated text of both normal and diseased appearances, OCT images are accompanied by fluorescein angiograms and standard fluoroscopic scans, thereby providing the reader with an ...
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    16. Three dimensional real-time image apparatus of ocular retina

      The disclosed content relates to a three dimensional real-time imaging apparatus of the ocular retina, which is associated with the most frequent ophthalmic diseases. In the present invention, the laser rays are formed into two dimensional ray surface sequentially with the time by using a polygon mirror motor and galvanometer and irradiated on the almost transparent retina through the pupil. The optical system is so arranged that the incident angles, relative to a retina, of the laser beams irradiated on the retina at respective moments may agree with the output angles of imaginary lines of the same laser rays reflected ...
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    17. Carl Zeiss Meditec to acquire Laser Diagnostic Technologies

      New Orleans—Carl Zeiss Meditec Inc. and Laser Diagnostic Technologies Inc. (LDT) announced that they have signed a definitive agreement for Carl Zeiss Meditec's acquisition of LDT. "This acquisition is another important milestone of our growth strategy," said Jim Taylor, president and chief executive officer of Carl Zeiss Meditec Inc. "It will further strengthen our technology portfolio and undisputed leadership in the growing market of glaucoma diagnosis and management. Looking forward, we will continue our aggressive growth through pursuit of both internal and external potentials." LDT President and CEO John Moore noted that this deal is a reflection of ...
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    18. Arrangements for coherence topographic ray tracing on the eye

      Topographic measurement of eye structures based on short coherence interferometry is the subject of the invention. The problem occurring in this connection is that longitudinal and transverse eye movements during signal registration lead to errors in the measured structure. The influences of longitudinal eye movements are compensated in that the reference beam, independent from the measurement beam, is directed to the corneal vertex and is reflected at the latter. The influences of longitudinal eye movements are minimized in that the transverse position of the eye is monitored by means of a direction-dependent registration of the light reflected at the corneal ...
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    19. System and method for non-contacting measurement of the eye

      Combined equipment for non-contacting determination of axial length (AL), anterior chamber depth (VKT) and corneal curvature (HHK) of the eye are also important for the selection of the intraocular lens IOL to be implanted, particularly the selection of an intraocular lens IOL to be implanted, preferably with fixation of the eye by means of a fixating lamp and/or illumination through light sources grouped eccentrically about the observation axis.
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    20. Optical mapping apparatus with adjustable depth resolution and multiple functionality

      The present invention relates to a multiple channel optical mapping apparatus which can deliver one or simultaneously at least two images of different depth resolutions or sequentially, images with different depth resolutions, or a combination of these images, or a single image with adjustable depth resolution. The multiple channels could be either multiple confocal channel and one or two optical coherence tomography channel, or two optical coherence tomography channels, or two confocal channels. The channels, either OCT or confocal can operate on the same wavelength or on different wavelengths. The apparatus can display both transversal as well as longitudinal images ...
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    21. Methods for measuring retinal damage

      Methods for measuring retinal damage resulting from an injury include calculating the slope of retinal thickness from the injury site to the periphery of the site. A shallower slope of retinal thickness correlates with a greater degree of damage resulting from the injury. The methods may also be useful to screen pharmaceuticals for potential neuroprotective effects against retinal injuries.
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    22. Method and device for the photoablation of the cornea with a laser beam

      In a method for photoablation on the cornea with a laser beam with the aid of which a multiplicity of consecutive partial ablation operations are undertaken, the thickness of the cornea is determined with the aid of a measuring device co-operating with a Michelson interferometer before and after each partial ablation operation. By using the thickness values determined, the measuring device guides the laser beam, with intensity values appropriately adjusted by it, over the cornea in a controlled fashion so as not to undershoot a prescribed cornea thickness while complying with a prescribed cornea profile. The measuring device operates with ...
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    1. (9 articles) National Institutes of Health
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