1. Articles in category: Ophthalmology

    11425-11448 of 11508 « 1 2 ... 474 475 476 477 478 479 480 »
    1. Optical coherence tomography in a patient with tobacco-alcohol amblyopia

      Aim To report optical coherence tomography (OCT) finding in a patient with tobacco-alcohol amblyopia. Methods A 45-year-old man presented with a gradual decrease in vision over 4 years. He had smoked a half to one pack of cigarettes per day and had consumed 350 cc of gin per day for 30 years. A detailed ophthalmologic examination was performed. Results His corrected visual acuities were 20/800 OD and 20/200 OS. A Goldmann visual field examination showed ceco-central scotomas in both eyes. OCT using a peripapillary Fast RNFL (retinal nerve fiber layer) programme showed a small decrease in the RNFL ...

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    2. Correlation between microaneurysm closure rate and reduction in macular thickness following laser photocoagulation of diabetic macular edema

      Aim To correlate the microaneurysmal closure rate measured on fundus fluorescein angiography (FFA) with reduction in macular thickness observed on optical coherence tomography (OCT) following laser photocoagulation of diabetic macular edema. Materials and methods A prospective observational case series. Fifty patients (50 eyes) of type II diabetes mellitus with clinically significant macular oedema (CSME) underwent focal/grid laser photocoagulation. OCT and FFA were performed at baseline and at 2 and 12 weeks following laser photocoagulation to measure the change in macular thickness and the number of leaking microaneurysms respectively. Statistical analysis was performed using paired-ttest and Pearson's correlation test ...
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      Mentions: Amod Gupta
    3. Step by Step Optical Coherence Tomography with Photo CD-ROM (Book)

      Step by Step Optical Coherence Tomography with Photo CD-ROM (Book)
      In "Step by Step OCT" we have endeavored to create a small book conveying only those things that would be important for the non-academic day to day user of OCT. A total of 25 chapters cover all aspects of the subject. Interprets OCT procedures in a simple and user-friendly manner. Describes various disease patterns with typical examples. Emphasizes macular, retinal and optic nerve head diseases. Summarizes important points in the tables and boxes. Useful equally to the students as well as ophthalmologist either in training or in practice.
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    4. Optovue, an ocular disease treatment co., raises $10.5M

      Optovue, a Fremont, Ca. maker of devices that improve diagnosis and treatment of ocular disease, has received $10.5 million in second round of funding, the company announced said. Based on high speed and high resolution Fourier-Domain OCT technology, the products help with retina conditions such as macular degeneration, diabetic retinopathy, glaucoma, and other macular diseases. Trevi Health Ventures led the round, which also included Acorn Campus Ventures, HNQ Asia Pacific, Harbinger Venture Management, iD SoftCapital and other individual investors. Optovue raised about $4.5 million in a first round
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      Mentions: Optovue Jay Wei
    5. Optovue raises $10.5M

      Ophthalmic device maker Optovue Corp. said Friday it received $10.5 million in second-round funding. Fremont-based Optovue said New York-based Trevi Health Ventures led the investment, followed by several partners from Optovue's previous funding round. The company said the money will be used to expand production of the its RTVue device, which was recently released outside the United States, as well as advance development of the company's product pipeline. Optovue also appointed John Moore, forme
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    6. Decreased optical coherence tomography-measured pericentral retinal thickness in patients with diabetes mellitus type 1 with minimal diabetic retinopathy

      Aim: A comparison of retinal thickness (RT) measurements with optical coherence tomography (OCT) in patients with type 1 diabetes mellitus (DM) and no or minimal diabetic retinopathy (DR) versus healthy controls. Methods: Fifty-three patients with type 1 DM with no or minimal DR underwent full ophthalmic examination, fundus photography and OCT. Mean RT measured by OCT was calculated for the central fovea, the fovea, the pericentral and the peripheral area of the macula, and compared to healthy controls. Results: Mean RT in the pericentral area was lower in patients with minimal DR (267 µm ± 20 µm; n = 23) compared to ...

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    7. Targeted stent placement and multi-stent therapy

      A trabecular flow model for producing treatment recommendations for patients with elevated intraocular pressure is disclosed. One method includes providing intraocular pressure measurements for a patient; providing aqueous cavity information, such as collector channel resistance and Schlemm's canal resistance, and determining a treatment recommendation for the patient based on the aforementioned parameters.
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    8. Fluid infusion methods for glaucoma treatment

      The invention relates to methods of treating glaucoma, such as a method that includes inserting a stent through an incision in an eye; the stent having an inflow portion that is in fluid communication with an outflow portion of the stent; transporting the stent from the incision through the anterior chamber of the eye to an aqueous cavity of the eye, such that the inflow portion of the stent is positioned in the anterior chamber and the outflow portion of the stent is positioned at the aqueous cavity; and infusing fluid from the inflow portion to the outflow portion of ...
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    9. Optical coherence tomography on autologous translocation of choroid and retinal pigment epithelium in age-related macular degeneration

      Purpose To analyse structural changes after autologous translocation of choroid and retinal pigment epithelium (RPE) in patients with age-related macular degeneration (AMD) using optical coherence tomography (OCT).Methods We performed a prospective nonrandomised study in 29 consecutive patients, who underwent submacular surgery with translocation of an autologous full-thickness graft of RPE, Bruch's membrane, and choroid. All patients had recent loss of reading vision due to AMD. OCT was performed before surgery and at 3- and 6- month follow-up to analyse the morphological appearance of the graft and the overlying retina.Results Maximum retinal thickness decreased from mean 408 m ...

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    10. Corneal and Anterior Segment Optical Coherence Tomography - Optovue (CAS-OCT)

      Device: OCT measurements Two OCT systems from Optovue Inc. (Fremont, CA) are used to perform preoperative scanning. The first OCT system is called RTVue. It is a FDA-approved Fourier-Domain OCT system. The second OCT sytem is call ACVue. It is an experimental Time-Domain OCT system and used to measure crystalline lens thickness and anterior chamber depth. The measurements from both OCT systems are used in selecting IOL power.
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    11. Methods, Systems And Computer Program For 3D-Registration Of Three Dimensional Data Sets Obtained By Preferably Optical Coherence Tomography Based On The Alignment Of Projection Images Or Fundus Images, Respectively (Wo 2007/016397)

      Methods of registration of three dimensional data sets obtained from a sample over time are provided. A first three dimensional data set is obtained from the sample at a first time. A first volume intensity projection (VIP) image is created from the first three dimensional data set. One or more first landmarks are identified in the first VIP image. A second three dimensional data set is obtained from the sample at a second time, different from the first time. A second VIP image is created from the second three dimensional data set. The one ore more first landmarks are identified ...
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    12. High-speed imaging of human retina in vivo with swept-source optical coherence tomography

      We present the first demonstration of human retinal imaging in vivo using optical frequency domain imaging (OFDI) in the 800-nm range. With 460-μW incident power on the eye, the sensitivity is 91 dB at maximum and >85 dB over 2-mm depth range. The axial resolution is 13 μm in air. We acquired images of retina at 43,200 depth profiles per second and a continuous acquisition speed of 84 frames/s (512 A-lines per frame) could be maintained over more than 2 seconds.
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    13. Optical coherent tomography measurements of the diffusion rate of water and drugs in an isolated and whole cornea

      The passive diffusion of drugs through the epithelial surfaces of an eye (the most widespread method for medical treatment of various diseases) is considered. The permeability of water and drugs through rabbit cornea was measured in the isolated cornea (separate from an eye) and in the whole cornea. The permeability coefficients of water and dexamethasone were estimated by the method of optical coherence tomography (OCT). Because multiple photon scattering introduces noise and distortions to the OCT signal, measurements were performed at depths up to 500 μm where most likely single scattering of light occurs in cornea. It is shown that ...
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    14. Evaluation of peripapillary detachment in pathologic myopia with en face optical coherence tomography

      Background A newly recognized lesion in pathologic myopia is peripapillary detachment of the retinal pigment epithelium (RPE) and retina. Recently introduced en face optical coherence tomography (OCT) provides not only cross-sectional but also coronal scans of the retina, and allows lateral extent visualization and thickness measurement of lesions. Methods Three patients presenting bilateral peripapillary yellow-orange lobulated area in high myopia have been evaluated with fluorescein angiography (FA), indocyanine green angiography (ICGA), en face OCT (OCT/SLO; Ophthalmic Technologies Inc, Toronto, Canada), and Humphrey visual field analyzer. Results In all eyes, en face OCT has shown the presence of a peripapillary ...
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    15. Iris recognition and tracking for optical treatment

      A system and method are provided in which an iris or eye image is taken during a refractive diagnostic analysis. The image is employed for aligning data from the analysis with data from other refractive analysis instruments, as well as aligning a refractive surgical tool, such as a laser, with the eye for treatment. Further, the stored iris image is compared with the patient's iris before treatment, verifying that the correct eye is to be treated with a developed treatment pattern. A variety of refractive instruments can be used, such as corneal topography systems and wavefront aberration systems.
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    16. Optical apparatus and method for comprehensive eye diagnosis

      An eye examination instrument is presented that can perform multiple eye tests. The instrument includes an illumination optical path and an imaging optical path, wherein a focus element in the illumination optical path is mechanically coupled to a focus element in the imaging optical path. In some embodiments, the eye examination instrument can perform a visual eye test, a fundus imaging test, and an optical coherence tomography test.
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      Mentions: Optovue Jay Wei Nidek
    17. Integrated scanning and ocular tomography system and method

      Systems and methods of the present invention measure at least one reflecting surface of an object disposed along an optical path. In some embodiments a measured optical interference signal for each of at least three wavelengths of reflected light may be used to determine a modulation of frequency components of a Fourier series. Frequency components of a Fourier series may be transformed to spatial components that describe intensities and positions of light reflected along an optical path.Systems and methods of the present invention permit rapid measuring and may monitor corneal thickness during surgery. The invention may do so by ...
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    18. System and method for predictive ophthalmic correction

      A system and method for providing a predictive outcome in the form of a predictive best instruction for a therapeutic ophthalmic correction of a patient's vision defects. The predictive best instruction is derived from prospective therapeutic-outcome-influencing, new information that is analyzed in conjunction with optimized, historical therapeutic-outcome information. The instruction is preferably an optimized, custom, photoablative algorithm for driving a photoablative, excimer laser. The instruction can be provided on a fee basis.
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      Mentions: Bausch & Lomb
    19. Everyday OCT: A Handbook for Clinicians and Technicians (Book)

      Everyday OCT: A Handbook for Clinicians and Technicians (Book)
      Authorities on OCT technology and imaging, Dr. Joel S. Schuman, Dr. Carmen A. Puliafito, and Dr. James G. Fujimoto review OCT and provide both the beginning and advanced user with expert pearls on how to effectively perform and interpret OCT imaging. Everyday OCT contains a wealth of technical information about the principles of operating the Stratus OCTTM and the main components of this medical diagnostic imaging technology. Everyday OCT explains how to: Set up and employ OCT technology Select and facilitate scans Ensure and assess the quality of scans Accurately interpret OCT images Additional Features: Over 200 color images Tips ...
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    20. Assessment of macular function by microperimetry in unilateral resolved central serous chorioretinopathy

      Purpose To determine macular sensitivity and fixation characteristics in patients with unilateral resolved central serous chorioretinopathy (CSC) using fundus-related microperimetry. Methods We reviewed 15 eyes with resolved CSC and 15 normal healthy eyes that had undergone fundus-related microperimetry. The macular sensitivity was measured using the recently introduced fundus-related microperimeter, MP-1. The best-corrected visual acuity (VA) (BCVA), mean retinal sensitivity in the central 10° (central microperimetry, cMP-1) and in the paracentral 10–20° (paracentral microperimetry, pMP-1), and fixation stability and location were determined and compared with measurements in control eyes. Results BCVA at the time of this study was 20/20 ...
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    21. Medical device and methods of use of glaucoma treatment

      The invention relates generally medical devices and methods for the treatment of glaucoma in an animal eye and, more particularly, to medical devices and methods for treating tissue of the trabecular meshwork and/or Schlemm's canal of the eye to restore or rejuvenate a portion or all of the normal physiological function of directing aqueous outflow for maintaining a normal intraocular pressure in the eye.
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    22. System for measuring the optical image quality of an eye in a contactless manner

      A system is used for contactless measurement of the optical imaging quality of an eye with an interferometer by which at least one light pulse with a short coherence length is coupled into the eye from a light source. The optical path length of at least one arm of the interferometer is varied for measuring the length of the eye until a typical interference pattern between a reflection of the cornea and a reflection of the retina of the eye occurs in a detector. This interference pattern together with a known path segment of the variation of the optical path ...
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    23. In vivo measurements of macular and nerve fibre layer thickness in retinal arterial occlusion

      Aim To investigate the structure–function relationship in patients with retinal arterial occlusion by measuring the macular and the peripapillary retinal nerve fibre layer (RNFL) thickness and the visual sensitivity. Methods This is an observational case series with three patients with central retinal arterial occlusion (CRAO) and two patients with branch retinal arterial occlusion (BRAO). The macular/peripapillary RNFL thickness and the visual field were measured with Stratus optical coherence tomography (OCT) and Humphrey visual field analyzer, respectively, at least 1 year after the diagnosis of CRAO or BRAO. Results The macular thickness, in particular the inner retinal layer, and ...
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    11425-11448 of 11508 « 1 2 ... 474 475 476 477 478 479 480 »
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    1. (9 articles) National Institutes of Health
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