1. Articles in category: Ophthalmology

    11305-11328 of 11631 « 1 2 ... 469 470 471 472 473 474 475 ... 483 484 485 »
    1. Intravitreal avastin for macular edmema secondary to retinal vein occlusion - a prospective study.

      Related Articles Intravitreal avastin for macular edmema secondary to retinal vein occlusion - a prospective study. Br J Ophthalmol. 2008 Jan 22; Authors: Kriechbaum K, Michels S, Prager F, Georgopoulos M, Funk M, Geitzenauer W, Schmidt-Erfurth U Abstract OBJECTIVE: To evaluate efficacy and safety of intravitreal bevacizumab (Avastin) in eyes with macular edema secondary to central (CRVO) or branch retinal vein occlusion (BRVO). METHODS: Twenty-eight consecutive patients (28 patients, 29 eyes, 8 CRVO, 21 BRVO) were enrolled in the study. Three intravitreal injections of 1 mg bevacizumab (0.04 ml) were administered at 4 week intervals; further retreatment was based on ...
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    2. Correlation between intraretinal changes in diabetic macular oedema seen in fluorescein angiography and optical coherence tomography

      Abstract.Purpose: To study the relationship between intraretinal optical coherence tomography (OCT) and fluorescein angiography (FA) findings in eyes with diabetic macular oedema (DMO).Methods: We carried out a retrospective observational case series. ...

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    3. Consistency of ocular coherence tomography fast macular thickness mapping in diabetic diffuse macular edema.

      OBJECTIVES: To investigate optical coherence tomography consistency on foveal thickness, foveal volume, and macular volume measurements in patients with and without diffuse diabetic macular edema. INTRODUCTION: Optical coherence tomography represents an objective technique that provides cross-sectional tomographs of retinal structure in vivo. However, it is expected that poor fixation ability, as seen in diabetic macular edema, could alter its results. Several authors have discussed the reproducibility of optical coherence tomography, but only a few have addressed the topic with respect to diabetic maculopathy. METHODS: The study recruited diabetic patients without clinically evident retinopathy (control group) and with diffuse macular edema ...
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    4. Intravitreal Bevacizumab and Triamcinolone Acetonide Combination Therapy for Exudative Neovascular Age-Related Macular Degeneration: Short-Term Optical Coherence Tomography Results.

      Intravitreal Bevacizumab and Triamcinolone Acetonide Combination Therapy for Exudative Neovascular Age-Related Macular Degeneration: Short-Term Optical Coherence Tomography Results. J Ocul Pharmacol Ther. 2008 Jan 17; Authors: Colucciello M Purpose: The aim of this study to describe the short-term anatomical results after an intravitreal injection of bevacizumab and triamcinolone acetonide in patients with foveal edema and/or subfoveal fluid associated with neovascularization (NV) due to age-related macular degeneration (AMD). Methods: A retrospective, noncomparative case series was conducted in patients with foveal edema and/or subfoveal fluid associated with NV due to AMD during a 3-month period. Patients were treated with intravitreal ...
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    5. A preliminary study on intravitreal injection of bevacizumab for treatment of neovascular age-related macular degeneration.

      [A preliminary study on intravitreal injection of bevacizumab for treatment of neovascular age-related macular degeneration.] Zhonghua Yan Ke Za Zhi. 2007 Oct;43(10):890-6 Authors: Tang SB, Liang XL, Hu J, Ding XY, Wan T, Guo MX, Hu YQ OBJECTIVE: To evaluate the short-term safety of intravitreous bevacizumab (Avastin) and its effects on visual acuity (VA) and subfoveal choroidal neovascularization (CNV) in patients with neovascular age-related macular degeneration (ARMD). METHODS: Single-center, uncontrolled clinical study. Five ARMD patients (5 eyes) with subfoveal CNV and best-corrected VA (BCVA) less than 0.1 were participated. Patients were treated with an intraviterous injection ...
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    6. Unusual coexistence of bilateral keratoconus and optic disc pit: A case report.

      Unusual coexistence of bilateral keratoconus and optic disc pit: A case report. Eur J Ophthalmol. 2008 Jan-Feb;18(1):134-7 Authors: Fasciani R, Mosca L, Giannico ML, Legrottaglie EF, Balestrazzi E PURPOSE. To report the unknown coexistence of bilateral optic disc pit and keratoconus. METHODS. A 23-year-old man with bilateral keratoconus underwent complete ophthalmology screening, with an unexpected detection of undiagnosed optic disc pit in both eyes. Computerized corneal topography (CT), Orbscan, corneal pachometry, endothelial microscopy, and optical coherence tomography (OCT) examination were performed. RESULTS. The corneal CT showed a keratoconus pattern in both eyes, evolved in the right eye ...
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    7. OCT and muti-focal ERG findings in spontaneous closure of bilateral traumatic macular holes.

      OCT and muti-focal ERG findings in spontaneous closure of bilateral traumatic macular holes. Doc Ophthalmol. 2008 Jan 18; Authors: Chen H, Zhang M, Huang S, Wu D Purpose To report the spontaneous closure of bilateral traumatic macular holes in a young patient, followed up with optical coherence tomography (OCT), muti-focal electroretinogram (mfERG), and Humphrey visual field examination. Methods A 25-year-old male who suffered from bilateral blunt trauma to the eyes and developed traumatic macular holes was followed with ophthalmic examination, OCT, mfERG, and Humphrey visual field examination. Results The OCT results revealed spontaneous closure in both eyes 2 weeks after ...
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    8. Intravitreal pegaptanib sodium for Irvine-Gass syndrome.

      Intravitreal pegaptanib sodium for Irvine-Gass syndrome. Eur J Ophthalmol. 2008 Jan-Feb;18(1):138-41 Authors: Querques G, Iaculli C, Delle Noci N PURPOSE. To report the novel use of intravitreal pegaptanib sodium for the treatment of refractory cystoid macular edema (CME) following cataract extraction. METHODS. A 72-year-old man presented with decreased visual acuity in his right eye 8 months after uncomplicated phacoemulsification cataract extraction and intraocular lens implantation. His bestcorrected visual acuity (BCVA) was 20/125 in the affected eye, and fundus examination revealed CME despite 6 months of oral and topical indomethacin therapy. Fluorescein angiography (FA) showed leakage in ...

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    9. Optical coherence tomography findings of incomplete posterior vitreoschisis with vitreomacular traction syndrome and impending macular hole: A case report.

      Optical coherence tomography findings of incomplete posterior vitreoschisis with vitreomacular traction syndrome and impending macular hole: A case report. Eur J Ophthalmol. 2008 Jan-Feb;18(1):147-9 Authors: Figus M, Carpineto P, Romagnoli M, Ferretti C, Di Antonio L, Nardi M PURPOSE. Vitreomacular traction syndrome is a clinical entity characterized by partial posterior vitreous detachment in combination with persistent macular adherence. Recently, optical coherence tomography (OCT) allowed visualization of incomplete posterior vitreoschisis leading to vitreomacular traction. METHODS. The authors report on a 57-year-old woman with blurred vision in her left eye. RESULTS. OCT scan showed incomplete posterior vitreoschisis with vitreomacular ...
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    10. Analysis of progressive ophthalmic lesion in a patient with subacute sclerosing panencephalitis.

      PURPOSE. To evaluate the progressive lesions affecting the visual system in a patient with subacute sclerosing panencephalitis (SSPE). METHODS. The authors observed a 15-year-old boy with SSPE. Since the diagnosis was made before the appearance of ocular manifestations, the authors recorded the progressive ocular lesions using various ophthalmic examinations. RESULTS. The patient showed no ophthalmic abnormalities until he developed a left homonymous hemianopia with sudden bilateral disturbed visual acuity. Severe progressive macular lesions including a pigment epithelial window defect by fluorescein angiography, a marked decrease in foveal thickness by optical coherence tomography, and an extensive disorder mainly specific to cone ...

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    11. METHOD AND DEVICE FOR OPTICAL DETECTION OF THE EYE

      (WO/2008/000403) CARL ZEISS MEDITEC AG [DE/DE]; Göschwitzer Strasse 51-52, 07745 Jena (DE) (All Except US). RUSSMANN, Christoph [DE/DE]; Coppanzer Weg 4A, 07745 Jena (DE) (US Only). DICK, Manfred [DE/DE]; Birkenweg 9, 07926 Gefell (DE) (US Only). RUSSMANN, Christoph [DE/DE]; Coppanzer Weg 4A, 07745 Jena (DE). DICK, Manfred [DE/DE]; Birkenweg 9, 07926 Gefell (DE). Title: Abstract: The invention r
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    12. OCT and muti-focal ERG findings in spontaneous closure of bilateral traumatic macular holes

      Abstract   Purpose To report the spontaneous closure of bilateral traumatic macular holes in a young patient, followed up with optical coherence tomography (OCT), muti-focal electroretinogram (mfERG), and Humphrey visual field examination. Methods A 25-year-old male who suffered from bilateral blunt trauma to the eyes and developed traumatic macular holes was followed with ophthalmic examination, OCT, mfERG, and Humphrey visual field examination. Results The OCT results revealed spontaneous closure in both eyes 2 weeks after trauma, and the macular holes remained closed in the 7 months of follow-up. Visual acuity improved to 0.7 in right and 0.9 in left ...
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    13. Inexpensive OCT glaucoma assessment tool can track MS activity

      January 16, 2008, Buffalo, NY--New research by neurologists at the University at Buffalo has shown that optical coherence tomography (OCT) also could be used as a surrogate marker of disease status in multiple sclerosis (MS) and to assess the effectiveness of new and current MS treatments.
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    14. Activity of neovascular lesions treated with bevacizumab: comparison between optical coherence tomography and fluorescein angiography.

      PURPOSE: To investigate whether examination with the non-invasive optical coherence tomography (OCT) alone is sufficient to ascertain the need of re-treatment with bevacizumab for exudative age-related macular degeneration (AMD) or the invasive fluorescein angiography (FA) is needed. METHOD: Two independent examiners reviewed FA and OCT images and performed a semi-quantitative assessment from 0=no activity to activity 1-3, mild, moderate and advanced, respectively. Weighted Kappa indices were performed to calculate the concordance between OCT and FA. RESULTS: A total of 153 OCT and FA examinations of 69 patients were evaluated, mean 2.2 examinations per patient. The mean age was ...
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    15. Pupillary dilation improves quality, reproducibility of OCT in glaucoma patients

      Performing optical coherence tomography after pupillary dilation appears to produce more reproducible, higher quality images for evaluating glaucoma patients compared with scans obtained on undilated eyes, according to a study by researchers in the United Kingdom. "Acquisition of high quality OCT images was not possible without pupillary dilatation in about 25% of the patients," the authors said.
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    16. Massachusetts Eye and Ear Infirmary Uses Newest Laser Treatment for People With Diabetic Eye Disease

      The Massachusetts Eye and Ear Infirmary recently acquired the newest laser for treating people with diabetic retinopathy. The Pattern Scan Laser Photocoagulator (Pascal) by OptiMedica is FDA-approved primarily for treatment of diabetic retinopathy and diabetic macular edema. Diabetic retinopathy is the most common diabetic eye disease and is a leading cause of blindness in American adults, according to the National Eye Institute of the National Institutes of Health (http://www.nih.nei.gov). The disease is caused by damage to blood vessels in the retina near the back part of the eye. The Pascal laser allows for faster, more precise ...
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    17. A Pilot Study.

      Related Articles INTRAVITREAL BEVACIZUMAB (AVASTIN) AS A TREATMENT FOR REFRACTORY MACULAR EDEMA IN PATIENTS WITH UVEITIS: A Pilot Study. Retina. 2008 Jan;28(1):41-45 Authors: Mackensen F, Heinz C, Becker MD, Heiligenhaus A PURPOSE:: Bevacizumab is a monoclonal antibody to vascular endothelial growth factor (VEGF) which has been successfully used for the treatment of age-related macular degeneration with choroidal neovascularization. As VEGF is involved in the pathomechanisms of inflammation and endothelial dysfunction the authors used bevacizumab as a last resort treatment in patients with persistent uveitic cystoid macular edema (CME). PATIENTS AND METHODS:: Persistent uveitic CME was defined by ...
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    18. Correlation between visual function and photoreceptor inner/outer segment junction in patients with retinitis pigmentosa.

      PurposeTo determine whether a significant correlation exists between the visual acuity or foveal thickness and the status of the inner and outer segment junction (IS/OS) of the photoreceptor in patients with retinitis pigmentosa (RP).MethodsThree hundred eyes of 163 patients with RP were examined with the optical coherence tomography (OCT). The IS/OS appeared as a distinct, highly reflective line just vitread of the retinal pigment epithelium in the OCT3 images. The IS/OS line was graded into three groups. The correlations between the grade of the IS/OS and age, best-corrected visual acuity (BCVA), and central foveal thickness ...
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    19. Prevalence Of Cystoid Macular Edema And Stability In Oct Retinal Thickness In Eyes With Retinitis Pigmentosa During A 48-Week Lutein Trial.

      Related Articles PREVALENCE OF CYSTOID MACULAR EDEMA AND STABILITY IN OCT RETINAL THICKNESS IN EYES WITH RETINITIS PIGMENTOSA DURING A 48-WEEK LUTEIN TRIAL. Retina. 2008 Jan;28(1):103-110 Authors: Adackapara CA, Sunness JS, Dibernardo CW, Melia BM, Dagnelie G PURPOSE:: To describe, in a group of patients with moderately advanced retinitis pigmentosa (RP), the prevalence of cystoid macular edema (CME), the variation in foveal thickness over a 48-week period, the correlation of visual acuity (VA) with retinal thickness, and the lack of response of CME to lutein administration. METHODS:: Optical coherence tomography (OCT) imaging of the macula and clinical ...
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    20. Photodynamic therapy in severe chronic central serous chorioretinopaty.

      Related Articles [Photodynamic therapy in severe chronic central serous chorioretinopaty.] Arch Soc Esp Oftalmol. 2008 Jan;83(1):9-14 Authors: Reche-Frutos J, Calvo-González C, Donate-López J, Sáenz-Francés-San-Baldomero F, Cerván-López I, García-Feijoó J, García-Sánchez J OBJECTIVE: To determine the efficacy of Photodynamic Therapy (PDT) in chronic Central Serous Chorioretinopathy (CSC). METHODS: Patients diagnosed with chronic CSC, with clinical evidence of activity and treated with Photodynamic Therapy, are included in this report. All were assessed by a complete ophthalmological examination, including assessment of the best corrected visual acuity (BCVA) using an ETDRS chart ...
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    21. The use of optical coherence tomography in hereditary optic neuropathies: description of a family.

      (Article in Spanish) CASE REPORT: This report describes two siblings, a woman aged 44 years and her brother aged 29 years, who both complained of visual loss in both eyes. The woman had bilateral optic nerve (ON) temporal pallor and severe reduction of ON fibre layer thickness in this area. Both she and her brother had cecocentral defects in perimetry and color vision deficiency with a marked tritanopia deficit. DISCUSSION: ON pallor, limited to the temporal region, is the basic criterion for the diagnosis of dominant optic atrophy. Optical coherence tomography can be a useful technique in defining the diagnosis ...
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    22. Intraoperative characteristics of the posterior vitreous cortex in patients with epiretinal membrane.

      Related Articles Intraoperative characteristics of the posterior vitreous cortex in patients with epiretinal membrane. Graefes Arch Clin Exp Ophthalmol. 2008 Jan 12; Authors: Yamashita T, Uemura A, Sakamoto T BACKGROUND: The aim of the study was to investigate the intraoperative characteristics of the posterior vitreous cortex in patients with epiretinal membranes. METHOD: Fifteen eyes of 15 patients with an idiopathic epiretinal membrane that had no posterior vitreous detachment (PVD) on both slit-lamp biomicroscopy and B-scan ultrasound examination were enrolled in this study. During vitrectomy, the relationship between the posterior vitreous cortex and the epiretinal membrane was observed when PVD was ...

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      Mentions: Taiji Sakamoto
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