1. Articles in category: Ophthalmology

    11257-11280 of 11984 « 1 2 ... 467 468 469 470 471 472 473 ... 498 499 500 »
    1. Features of Age-Related Macular Degeneration Assessed with 3-Dimensional-Fourier-Domain OCT

      Background/Aims: Age-related macular degeneration (AMD) is amongst the leading causes of severe visual loss in individuals over 60 years old. Retinal changes associated with AMD were previously studied by time-domain optical coherence tomography (OCT). Recently, Fourier-Domain OCT (FD-OCT) has been introduced. FD-OCT provides increased scan resolution, scanning speed and generates 3-dimensional OCT images. The purpose of this study was to demonstrate features of AMD assessed with high-density scanning 3d-FD-OCT (Topcon 3d-OCT1000). Methods: The study was designed as a prospective, observational case series. Five patients with typical morphological changes due to AMD were chosen based on funduscopic findings. Eyes with ...
      Read Full Article
    2. Early Morphologic Changes and Functional Abnormalities in Group 2A Idiopathic Juxtafoveolar Retinal Telangiectasis Using Spectral Domain Optical Coherence Tomography and Microperimetry

      Aims: To report early morphologic changes and functional abnormalities in group 2A idiopathic juxtafoveolar retinal telangiectasis (IJRT) using spectral domain optical coherence tomography (SD-OCT) and microperimetry. Methods: Six eyes (three patients; average age, 64 years) with group 2A IJRT were examined using SD-OCT and microperimetry. Results: On SD-OCT, breaks in the highly reflective line, considered the boundary between the photoreceptor inner and outer segments, at the temporal to the fovea and corresponding to the telangiectasis lesions were observed in all eyes. Highly reflective tissue was observed in the outer retinal layer in five eyes. In three eyes with a right-angle ...
      Read Full Article
    3. OTI received a warning letter in connection with a FDA

      On March 25, 2008, OTI received a warning letter in connection with a FDA inspection of OTI's facilities in July and August of 2007. The warning letter cited several deficiencies in OTI's quality, record keeping, and reporting systems relating to certain of OTI's products, including the OTI Scan 1000, OTI Scan 2000, and OTI OCT/SLO combination imaging system. Based upon the observations noted in the warning letter, OTI is not currently in compliance with cGMP. The FDA indicated that it has issued an Import Alert and may refuse admission of these products. As a result, we ...
      Read Full Article
    4. Monte Carlo modeling of corneal and retinal Optical Coherence Tomography imaging

      Monte Carlo simulations of OCT images of cornea and retina was performed for various setup parameters. Several models of cornea and retina were implemented; the optical parameters or the model were chosen basing on the experimental results. Obtained simulated image exhibits qualitative agreement with the experimental ones allowing for preliminary numerical study of OCT technique for ocular structure and ophthalmologic diseases diagnostics.
      Read Full Article
    5. Physical Sciences Inc. Adaptive Optics Spectral Domain Optical Coherence Tomography

      Physical Sciences Inc. Adaptive Optics Spectral Domain Optical Coherence Tomography
      The adaptive optics spectral domain optical coherence tomography (AO-SDOCT) system combines adaptive optics for detection and correction of ocular aberrations with high-speed SDOCT. The combination of AO for increased lateral resolution with high axial resolution low coherence interferometry allows micron-level resolution of retinal structures and layers.
      Read Full Article
    6. Detection of the Optic Nerve Head Neural Canal Opening within Three-Dimensional Histomorphometric and Spectral Domain Optical Coherence Tomography Data Sets.

      Purpose: To assess the ability to detect the neural canal opening (NCO) and its characteristics within 3-D histomorphometric and 3-D spectral domain optical coherence tomography (SD-OCT) reconstructions of the optic nerve head from non-human primate (NHP) eyes. Methods: NCO was delineated within 40 radial, sagittal sections of 3-D histomorphometric reconstructions of 44 normal eyes of 38 NHPs, each perfusion-fixed at IOP 10 mmHg, and Heidelberg Spectralis 3-D SD-OCT volumes acquired in vivo from a separate group of 33 normal eyes of 24 NHPs. Within all reconstructions, a least-squares ellipse was fitted to the 80 NCO points. For each eye, the ...
      Read Full Article
    7. Spectral Domain Optical Coherence Tomography for Quantitative Evaluation of Drusen and Associated Structural Changes in Non-Neovascular Age Related Macular Degeneration

      Background/Aims: To demonstrate how spectral domain optical coherence tomography (SDOCT) can better evaluate drusen and associated anatomic changes in eyes with non-neovascular age related macular degeneration (AMD) compared to time domain optical coherence tomography (TDOCT). Methods: Images were obtained from 3 eyes of 3 patients with AMD using an experimental SDOCT system. Both a Titanium-sapphire (Ti:Sapphire) laser and a superluminescent diode (SLD) was used as a broadband light source to achieve cross-sectional images of the retina. Qualitative and quantitative analysis was done of structural changes associated with non-neovascular AMD. An automated algorithm was developed to analyze drusen size ...

      Read Full Article
    8. Analysis of Macular Thickness in British Population Using Optical Coherence Tomography (oct): An Emphasis on Interocular Symmetry

      Purpose: To evaluate macular thickness measurements in normal subjects from British origin, to assess interocular asymmetry using optical coherence tomography (OCT) and to establish standard values for macular and foveal thickness. Methods: Two hundred eyes of 100 normal individuals underwent serial scans using fast macular thickness map protocol in the Stratus OCT version 3.51, with foveal fixation. Minimum foveal thickness (MFT), central 1 mm average foveal thickness (AFT), total foveal volume (TFV) and total macular volume (TMV at 6 mm) of both eyes were assessed. The interocular asymmetry was measured and statistically analyzed. Results: The mean ± SD (N = 200 ...

      Read Full Article
    9. One-Year Results and Anterior Segment Optical Coherence Tomography Findings of Descemet Stripping Automated Endothelial Keratoplasty Combined With Phacoemulsification

      Objective  To report 1-year results and anterior segment optical coherence tomography findings of Descemet stripping automated endothelial keratoplasty combined with phacoemulsification in patients with cataract and Fuchs endothelial dystrophy. Methods  Twelve eyes of 11 patients with at least 1-year follow-up were retrospectively reviewed. Measured variables included best spectacle-corrected visual acuity, refractive spherical equivalent and predictability, anterior corneal keratometric values, complications, and anterior segment optical coherence tomography findings. Results  The mean follow-up was 14.33 months (range, 12-18 months). The best spectacle-corrected visual acuity was unchanged (8%) or improved (92%) in all eyes compared with the preoperative levels. A mean (SD ...
      Read Full Article
    10. Automated Diagnosis of Glaucoma Using Digital Fundus Images

      Abstract  Glaucoma is a disease of the optic nerve caused by the increase in the intraocular pressure of the eye. Glaucoma mainly affects the optic disc by increasing the cup size. It can lead to the blindness if it is not detected and treated in proper time. The detection of glaucoma through Optical Coherence Tomography (OCT) and Heidelberg Retinal Tomography (HRT) is very expensive. This paper presents a novel method for glaucoma detection using digital fundus images. Digital image processing techniques, such as preprocessing, morphological operations and thresholding, are widely used for the automatic detection of optic disc, blood vessels ...
      Read Full Article
    11. Applications of anterior segment optical coherence tomography in ophthalmology

      The background, technical characteristics and operation procedures of anterior segment optical coherence tomography (OCT) are introduced. The ophthalmic applications of this technique are summarized. The initial studies showed that anterior segment OCT can be a promising tool for the observation of image and analysis of the cornea, the imaging and biological measuring of the anterior chamber, the observation of image and quantitative evaluation of the anterior chamber angle, the observation of image and assessment of phakic intraocular lenses, the observation of image and evaluation of trabeculectomy blebs as well as the observation of ocular accommodation. PMID: 18683707 [PubMed - in process]
      Read Full Article
    12. Macular Holes and Macular Pucker: The Role of Vitreoschsis as Imaged By Optical Coherence Tomography/Scanning Laser Ophthalmoscopy

      Macular Holes and Macular Pucker: The Role of  Vitreoschsis as Imaged By Optical Coherence Tomography/Scanning Laser Ophthalmoscopy
      Purpose The pathogenesis of macular pucker and macular holes is poorly understood. Anomalous posterior vitreous detachment (PVD) and vitreoschisis have been proposed as possible mechanisms. This study used clinical imaging to seek vitreoschisis and study the topographic features of macular pucker and macular holes. Methods Combined optical coherence tomography and scanning laser ophthalmoscopy (OCT/SLO) was performed in 45 eyes with macular hole and 44 eyes with macular pucker. Longitudinal imaging was used to identify vitreoschisis and measure retinal thickness. The topographic features of eyes with macular hole with eccentric macular contraction were compared to 24 eyes with unifocal macular ...
      Read Full Article
    13. Quantitative Evaluation of Anterior Segment Parameters in the Era of Imaging

      Quantitative Evaluation of Anterior Segment Parameters in the Era of Imaging
      Purpose To review the parameters for quantitative assessment of the anterior segment and iridocorneal angle and to develop a comprehensive schematic for the evaluation of angle anatomy and pathophysiology by high-resolution imaging. Methods The published literature of the last 15 years was reviewed, analyzed, and organized into a construct for assessment of anterior segment processes. Results Modern anterior segment imaging techniques have allowed us to devise new quantitative parameters to improve the information obtained. Ultrasound biomicroscopy, slit-lamp optical coherence tomography, and anterior segment optical coherence tomography provide high-resolution images for analysis of physiologic and pathologic processes. These include iridocorneal angle ...
      Read Full Article
    14. Optical Coherence Tomography Measurements and Analysis Methods in Optical Coherence Tomography Studies of Diabetic Macular Edema

      Objective: To evaluate optical coherence tomography (OCT) measurements and methods of analysis of OCT data in studies of diabetic macular edema (DME). Design Associations of pairs of OCT variables and results of 3 analysis methods using data from 2 studies of DME. Participants Two hundred sixty-three subjects from a study of modified Early Treatment of Diabetic Retinopathy Study (mETDRS) versus modified macular grid (MMG) photocoagulation for DME and 96 subjects from a study of diurnal variation of DME. Methods Correlations were calculated for pairs of OCT variables at baseline and for changes in the variables over time. Distribution of OCT ...
      Read Full Article
    15. In vivo measurement of erythrocyte velocity and retinal blood flow using adaptive optics scanning laser ophthalmoscopy

      In vivo measurement of erythrocyte velocity and retinal blood flow using adaptive optics scanning laser ophthalmoscopy
      Zhangyi Zhong, Benno L. Petrig, Xiaofeng Qi, Stephen A. Burns. In vivo measurement of retinal blood flow is obtained by measuring the blood velocity of erythrocytes and lumen diameters of the blood vessels using an adaptive optics scanning laser ophthalmoscope. Erythrocyte velocity is measured by tracking erythrocytes moving across a horizontal scanning line. ... [Opt. Express 16, 12746-12756 (2008)]
      Read Full Article
    16. Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography in Non-glaucomatous Taiwanese.

      Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography in Non-glaucomatous Taiwanese. J Formos Med Assoc. 2008 Aug;107(8):627-34 Authors: Peng PH, Lin HS Background/Purpose: Assessment of the peripapillary retinal nerve fiber layer (RNFL) is essential for neuroretinal diseases, especially for early prediction of glaucomatous damage. The purpose of this study was to measure RNFL thickness by Stratus optical coherence tomography (OCT) in normal Taiwanese subjects according to age group. Methods: The thickness of the RNFL around the disc of normal subjects was obtained, after pupil dilation, by means of 3.4 mm diameter fast mode ...
      Read Full Article
    17. Clinical Spectrum of Lamellar Macular Defects Including Pseudoholes and Pseudocysts Defined By Optical Coherence Tomography

      Objective: To present the clinical spectrum of lamellar macular defects and describe the different subtypes based on their OCT configuration and visual prognosis. Methods: The retrospective observational case series reviewed OCT scans of 92 eyes with lamellar macular defects. Lamellar macular defects were categorized into subtypes of macular pseudohole (MPH), lamellar macular hole (LMH), and foveal pseudocyst (FP) according to their OCT morphology. The defects were quantitatively characterized in terms of base diameter, depth, central foveal thickness, and examined for the presence of associated epiretinal membranes (ERM). Results: Visual acuity (VA) was significantly correlated with the central foveal thickness and ...
      Read Full Article
    18. Aditya Jyot Eye Hospital launches 4th generation OCT machine

      Aditya Jyot Eye Hospital, one of the leading eye hospital and institutes in Mumbai, launched the latest 4th generation Optical Coherence Tomography (OCT) which will combine evaluation of retina, cornea and glaucoma in one. The state of the art Optovue RTvue 100 - 3D fourier domain OCT machine with its unique software capabilities will enable precise and thorough eye evaluation. Union minister Sushil Kumar Shinde and model Aditi Govitrikar inaugurated the new facility at the Aditya Jyot hospital which is the first hospital in Mumbai to launch such a facility. Marking years of dedicated efforts towards eradicating blindness and providing vision ...
      Read Full Article
    19. Glaucoma care and clinical profile in Priest Hospital, Thailand.

      Glaucoma care and clinical profile in Priest Hospital, Thailand. J Med Assoc Thai. 2008;91 Suppl 1:S111-8 Authors: Sothornwit N, Jenchitr W, Pongprayoon C OBJECTIVE: To assess the prevalence, mechanism and status of glaucoma, and to investigate the magnitude of visual impairment from glaucoma and its relating factors in Buddhist priest and novices. MATERIAL AND METHOD: Cross-sectional study of 190 patients treated in Glaucoma service, Priest hospital was performed. One hundred thirty seven patients with glaucoma and suspected glaucoma had comprehensive ophthalmic examination included interview on medical and ocular history, visual acuity, applanation tonometry, gonioscopy, optic disc, visual field ...
      Read Full Article
    20. Localization of nerve fiber bundles by polarization-sensitive optical coherence tomography.

      Localization of nerve fiber bundles by polarization-sensitive optical coherence tomography. J Neurosci Methods. 2008 Jul 16; Authors: Nakaji H, Kouyama N, Muragaki Y, Kawakami Y, Iseki H Diagnostic modalities that can distinguish brain tumors from eloquent cortices or nerve fiber bundles are important for neurosurgery. For identifying nerve fiber bundles, various techniques such as diffusion tensor imaging and subcortical stimulation mapping have been used. In this article, we propose localization of nerve fiber bundles by polarization-sensitive optical coherence tomography (PS-OCT) for the first time. PS-OCT performs tomographic imaging by measuring the travel distance and the change in polarization of the ...
      Read Full Article
    11257-11280 of 11984 « 1 2 ... 467 468 469 470 471 472 473 ... 498 499 500 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (9 articles) Duke University
    2. (7 articles) University of Miami
    3. (6 articles) Oregon Health & Science University
    4. (5 articles) Center for Ophthalmic Optics and Lasers
    5. (5 articles) National Institutes of Health
    6. (4 articles) Massachusetts Eye and Ear Infirmary
    7. (4 articles) Harvard University
    8. (3 articles) Columbia University
    9. (3 articles) University of Southern California
    10. (3 articles) University of Washington
    11. (2 articles) Fudan University
    12. (2 articles) Stanford University
  4. People in the News

    1. (5 articles) David Huang
    2. (3 articles) Adam Wax
    3. (3 articles) Philip J. Rosenfeld
    4. (3 articles) Francesco Bandello
    5. (3 articles) Ruikang K. Wang
    6. (3 articles) Bruno Lumbroso
    7. (2 articles) Lawrence A. Yannuzzi
    8. (2 articles) Cynthia A. Toth
    9. (2 articles) Teresa C. Chen
    10. (2 articles) Sharon F. Freedman
    11. (2 articles) Joseph A. Izatt
    12. (2 articles) Benjamin J. Vakoc
  5. OCT Companies in the News

    1. (4 articles) Lumedica
    2. (2 articles) Optovue
    3. (2 articles) Carl Zeiss Meditec
    4. (2 articles) Bioptigen
    5. (1 articles) Nidek
    6. (1 articles) Heidelberg Engineering
    7. (1 articles) Canon Medical Systems
    8. (1 articles) Notal Vision
    9. (1 articles) Specsavers