1. Articles in category: Ophthalmology

    11233-11256 of 11500 « 1 2 ... 466 467 468 469 470 471 472 ... 478 479 480 »
    1. Use of anatomical measures of idiopathic macular hole obtained through optical coherence tomography as a predictive factor in visual results: a pilot study.

      PURPOSE: To evaluate the anatomy of idiopathic macular hole (IMH) using Optical Coherence Tomography (OCT) and to construct a prognostic index that can be correlated with the visual outcomes and the anatomical closing. METHODS: Prospective study, in which 22 eyes with IMH had been evaluated through OCT in the daily postoperative period of IMH surgery. The Prognostic of Macular Hole Index (PMHI) was created which was correlated with the anatomical result and the postoperative visual acuity (VA) six months after surgery. RESULTS: Sixteen eyes (72.7%) got anatomical closing at the end of six months of follow-up. On analysis of ...
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    2. Intravitreal pegaptanib sodium (Macugen) for refractory cystoid macular edema in pericentral retinitis pigmentosa.

      Related Articles Intravitreal pegaptanib sodium (Macugen) for refractory cystoid macular edema in pericentral retinitis pigmentosa. Int Ophthalmol. 2007 Dec 22; Authors: Querques G, Prascina F, Iaculli C, Noci ND The purpose of this paper was to describe a patient with pericentral retinitis pigmentosa (RP) and cystoid macular edema (CME) refractory to oral acetazolamide alone who was successfully treated with adjunctive pegaptanib sodium. A 33-year-old man presented with decreased vision and a best-corrected visual acuity (BCVA) in his left eye of 20/200 due to CME secondary to RP. Although he had been treated daily for 1 month with 500 mg ...
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    3. The status of diabetic retinopathy and diabetic macular edema in patients with type 2 diabetes: a survey from Beixinjing District of Shanghai city in China.

      The status of diabetic retinopathy and diabetic macular edema in patients with type 2 diabetes: a survey from Beixinjing District of Shanghai city in China. Ophthalmologica. 2008;222(1):32-6 Authors: Wang N, Xu X, Zou H, Zhu J, Wang W, Ho PC Diabetic macular edema (DME) is the major cause of vision loss in patients with diabetic retinopathy (DR). The purpose of this study was to assess the prevalence of DR and DME in a community in China and to analyze the characteristics of their optical coherence tomography (OCT) images. This study was an incidence survey based on data ...

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    4. Effects of Endogenous Cyclotronic Ionic Resonance (icr) on Macular Diabetic Edema: Preliminary Results.

      Effects of Endogenous Cyclotronic Ionic Resonance (ICR) on Macular Diabetic Edema: Preliminary Results. Electromagn Biol Med. 2007;26(4):293-8 Authors: D'Andrea P, Maurizio L The intent in this research was to verify the effects of the application of low frequency magnetic fields to cases of macular diabetic edema. We treated six patients afflicted by non-proliferating diabetic retinopathy with macular oedema. Quantitative clinical appraisals of the retinal thickness were obtained for the Optical Coherence Tomography (OCT I). None of the cases affected by non-cystoid macular oedema (non-CMO), or with a relevant ischemic component, evidenced by retinal fluorangiography, had further ...
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    5. Rat model for anterior segment intraocular surgery induced blood-retinal barrier breakdown.

      Rat model for anterior segment intraocular surgery induced blood-retinal barrier breakdown. Ophthalmologica. 2008;222(1):42-7 Authors: Xie MS, Xu GX, Huang Y PURPOSE: To develop a practical rat model of blood-retinal barrier (BRB) breakdown induced by anterior segment intraocular surgery. METHODS: A 27-gauge needle attached to infusion tubing running to a bottle of balanced salt solution was inserted through the limbus into the rat anterior chamber. The pressure of the balanced salt solution was oscillated from 0 to 12 mm Hg above the atmospheric pressure for 30 times. The needle was removed and the anterior chamber was formed. Then ...
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    6. Early OCT changes of neuroretinal foveal thickness after first versus repeated PDT in AMD.

      Early OCT changes of neuroretinal foveal thickness after first versus repeated PDT in AMD. Int Ophthalmol. 2007 Dec 20; Authors: Landa G, Bukelman A, Katz H, Pollack A Purpose To compare early optical coherence tomography (OCT) changes in neuroretinal foveal thickness (NFT) after first versus repeated photodynamic treatment (PDT) in eyes with choroidal neovascularization (CNV) due to age-related macular degeneration (AMD). Methods This is a prospective comparative case series study. Consecutive AMD patients, treated with PDT due to subfoveal CNV, were enrolled. The eyes were divided into two groups: group A included eyes that had received the first initial treatment ...
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    7. Study on macular morphology after removal of the idiopathic epiretinal membrane using the optical coherence tomography (OCT): a pilot study

      PURPOSE: To describe the relation between visual results and macular morphology through optical coherence tomography (OCT) in patients submitted to removal of the idiopathic epiretinal membranes. METHODS: Ten eyes of ten patients with diagnosis of idiopathic epiretinal membranes underwent standard 20-G pars plana vitrectomy. Posterior hyaloid attachments were identified and dealt with. Idiopathic epiretinal membranes were removed in all cases. Corrected visual acuity, retinography, fluorescein angiography, fundus biomicroscopy and the optical coherence tomography in the pre- and postoperative periods were performed in all patients. In OCT, three characteristics were considered in each image: presence of foveal depression, presence of cystoid ...
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    8. Assessment of anterior segment parameters under photopic and scotopic conditions in Indian eyes using anterior segment optical coherence tomography

      The Eye Research Foundation, Vijaya Hospital, Chennai, India Correspondence Address: Dacosta Shaun The Eye Research Foundation, Vijaya Hospital, 180 NSK Salai, Chennai - 600 026 India Purpose: To compare the anterior segment parameters in photopic and scotopic conditions using anterior segment optical coherence tomography (AS OCT) in Indian eyes. Materials and Methods: One hundred eyes of 100 normal subjects of both sexes, aged 19 to 76 years, underwent anterior segment evaluation by AS OCT (Vis
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    9. Maculopathy in uveitis of juvenile idiopathic arthritis: an optical coherence tomography study

      Aim: The aim of this study was to examine the frequency and characteristics of macular lesions observed in juvenile idiopathic arthritis (JIA) uveitis, using optical coherence tomography (OCT). Methods: In this cross-sectional study, 38 consecutive patients were recruited from a tertiary referral center in uveitis. All eyes with JIA uveitis underwent complete ophthalmic examination including OCT 3. Exclusion criterion was the inability to obtain OCT scans. Flare and visual acuity were also analysed by using linear regression. Results: We analysed foveal thickness (FT) and central foveal thickness (CFT), using software mapping, to describe macular lesions in 61 eyes. Maculopathy was ...
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    10. Efficacy of intravitreal bevacizumab for polypoidal choroidal vasculopathy

      Aims: The aim of the study was to assess the short-term efficacy of intravitreal injections of bevacizumab for polypoidal choroidal vasculopathy (PCV). Methods: Intravitreal bevacizumab (1 mg) was injected into 11 eyes of 11 patients with PCV in this retrospective, interventional case series. The main outcome measure was the change in the polypoidal vessels on indocyanine green angiography (IA) 3 months after injection. The foveal height determined by optical coherence tomography and the best-corrected visual acuity (BCVA) also were evaluated before and after treatment. Results: At baseline, subretinal fluid was observed in five eyes and a pigment epithelial detachment in ...
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    11. Intravitreal triamcinolone versus bevacizumab for treatment of refractory diabetic macular oedema (ibeme study)

      Background/aims: The aim of this study was to compare the morphological and visual acuity outcomes associated with a single intravitreal injection of triamcinolone acetonide versus bevacizumab for the treatment of refractory diffuse diabetic macular oedema. Methods: Twenty-eight patients were randomly assigned to receive a single intravitreal injection of either 4 mg/0.1 ml triamcinolone acetonide or 1.5 mg/0.06 ml bevacizumab. Comprehensive ophthalmic evaluation was performed at baseline and at weeks 1, 4, 8 (±1), 12 (±2) and 24 (±2) after treatment. Main outcome measures included central macular thickness measured with optical coherence tomography (OCT) and ...
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    12. Trans-Tenon's retrobulbar triamcinolone acetonide injection for macular oedema related to branch retinal vein occlusion

      Background: The aim of the study was to evaluate the safety and effectiveness of trans-Tenon’s retrobulbar triamcinolone acetonide (TA) injection for macular oedema associated with branch retinal vein occlusion (BRVO). Methods: We reviewed the medical records of 50 consecutive patients with macular oedema associated with BRVO who were treated with trans-Tenon’s retrobulbar TA injection (20 mg) as initial treatment for a follow-up period of at least 12 months. Foveal thickness determined by optical coherence tomography, visual acuity, intraocular pressure (IOP) and cataract progression were measured. Results: The mean duration between oedema onset and TA injection was 4.9 ...
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    13. Central visual field impairment during and following cystoid macular oedema

      Aim: To determine differential light threshold values obtained with the Micro Perimeter 1 (MP1) in uveitis patients suffering from cystoid macular oedema (CMO) and to compare these measures to retinal thickness. Methods: Static threshold perimetry was performed with the MP1 Microperimeter in 27 eyes of 21 patients with a history of chronically recurring CMO. Active CMO was confirmed in 19 eyes. Eight eyes with a history of recurrent CMO were found to have normal foveal contours in optical coherence tomography (OCT). Differential light threshold values (MP1) were compared with the corresponding retinal thickness measures (OCT). Results: Mean differential threshold values ...
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    14. Degree of angle closure and extent of peripheral anterior synechiae: an anterior segment OCT study

      Aims: To evaluate the relationship between angle width as determined by anterior segment optical coherence tomography (AS-OCT) and the presence of peripheral anterior synechiae (PAS). Methods: This was a prospective observational case series in which 203 subjects with primary angle closure or open angles were recruited. Images of the nasal, temporal and inferior angles were obtained with AS-OCT in dark conditions. Subjects then underwent gonioscopy by an independent examiner who was masked to the AS-OCT findings. PAS were identified by gonioscopy and defined as abnormal adhesions of the iris to the angle that were at least half a clock hour ...
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    15. Half-top-hat a new wound configuration for penetrating keratoplasty

      Aims: To describe a new, simpler method of achieving the advantages of a lamellar wound configuration in penetrating keratoplasty (PKP)—the half-top-hat (HTH) configuration. Methods: The donor corneal button was prepared in a top-hat configuration, as previously described. It consisted of a central, full-thickness part, 7–8 mm in diameter, surrounded by a peripheral lamellar wing of deep stroma and endothelium that was 0.5 mm in width (wing diameter 8–9 mm). The recipient bed was prepared by a straight full thickness trephination with a suction trephine. The donor button was positioned by sliding the peripheral wing under the ...
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    16. Simultaneous imaging of human cone mosaic with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography

      M. Pircher, R. J. Zawadzki, J. W. Evans, J. S. Werner, C. K. Hitzenberger We describe a novel instrument capable of acquiring, simultaneously, adaptive optics enhanced scanning laser ophthalmoscopy and optical coherence tomography (OCT) images of the human cone mosaic in vivo. The OCT system is based on transversal scanning of the sample with a line scan rate of 14 kHz, ... [Opt. Lett. 33, 22-24 (2008)]
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    17. Stratus OCT in Dominant Optic Atrophy: Features Differentiating it From Glaucoma.

      PURPOSE: To describe the Stratus optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) thickness profile of dominant optic atrophy (DOA), to differentiate it from that of glaucoma. METHODS: RNFL thickness was measured using Stratus OCT in 32 eyes of 16 DOA patients. RESULTS: The temporal-most clock hour measurement was outside the 95% normal limit in 29 of the 32 DOA eyes (90.6%). The pattern of RNFL damage was bilaterally symmetrical in location and severity in all subjects. CONCLUSION: Stratus OCT shows characteristic findings differentiating DOA from glaucoma. PMID: 18091450 [PubMed - in process]
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    18. Inexpensive Glaucoma Assessment Tool Can Track MS Activity

      University at Buffalo Reporter - New research by neurologists at the University at Buffalo has shown that a technique called optical coherence tomography, or OCT, a simple and inexpensive measure employed currently to assess glaucoma, also could be used as a surrogate marker of ...
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    19. Fourier domain optical coherence tomography with a linear-in-wavenumber spectrometer.

      Related Articles Fourier domain optical coherence tomography with a linear-in-wavenumber spectrometer. Opt Lett. 2007 Dec 15;32(24):3525-7 Authors: Hu Z, Rollins AM We describe Fourier domain optical coherence tomography equipped with a novel linear-in-wavenumber spectrometer. The presented device linearizes the spectral dispersion of the spectrometer in wavenumber using a specifically designed prism. The spectral linearity in wavenumber makes numerical interpolation into wavenumber unnecessary, reduces computing time, and furthermore results in improvement of the falloff of signal with image range inherent to frequency-domain optical coherence tomography imaging. Experiments demonstrate the improvement of the falloff and agree with the expected ...
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    20. Correlation between retinal nerve fibre layer thickness and retinal sensitivity

      Purpose: To evaluate the relationship between retinal nerve fibre layer (RNFL) thickness measured by optical coherence tomography (OCT) and light threshold values obtained with the Micro Perimeter 1 (MP1). Methods: Forty-nine normal subjects and 37 glaucoma patients were included. Thickness of the RNFL around the optic disc was measured with Stratus OCT scans, and static threshold perimetry was performed with the MP1 at the same visit. Total average and mean 12-clock-hour RNFL thickness were measured with Stratus OCT. An automated 4-2-1 staircase strategy with Goldmann III stimuli was used for MP1. The correspondence between Stratus OCT and MP1 RNFL measurements ...
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