1. Articles in category: Ophthalmology

    11185-11208 of 11520 « 1 2 ... 464 465 466 467 468 469 470 ... 478 479 480 »
    1. The effect of acute hyperglycemia on retinal thickness and ocular refraction in healthy subjects.

      The effect of acute hyperglycemia on retinal thickness and ocular refraction in healthy subjects. Graefes Arch Clin Exp Ophthalmol. 2008 Jan 25; Authors: Wiemer NG, Eekhoff EM, Simsek S, Heine RJ, Ringens PJ, Polak BC, Dubbelman M PURPOSE: To quantify the retinal thickness and the refractive error of the healthy human eye during hyperglycemia by means of optical coherence tomography (OCT) and Hartmann-Shack aberrometry. METHODS: Hyperglycemia was induced in five healthy subjects who were given a standard oral glucose tolerance test (OGTT) after a subcutaneous injection of somatostatin. Main outcome parameters were the central, pericentral and peripheral thickness of the ...
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    2. Longitudinal analysis of retinal changes after branch retinal artery occlusion using optical coherence tomography.

      Related Articles Longitudinal analysis of retinal changes after branch retinal artery occlusion using optical coherence tomography. Optometry. 2008 Feb;79(2):85-9 Authors: Asefzadeh B, Ninyo K BACKGROUND: Branch retinal artery occlusion (BRAO) causes inner retinal ischemia leading to permanent inner retinal dysfunction and visual field loss in affected retinal sectors. Optical coherence tomography (OCT) offers a novel way to evaluate in vivo retinal morphologic changes in BRAO in both acute and longitudinal phases. This case report describes OCT findings in BRAO at acute presentation and at follow-up, including the longitudinal evaluation of retinal and peripapillary retinal nerve fiber layer ...
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    3. Imaging Implanted Keratoprostheses With Anterior-Segment Optical Coherence Tomography and Ultrasound Biomicroscopy.

      Related Articles Imaging Implanted Keratoprostheses With Anterior-Segment Optical Coherence Tomography and Ultrasound Biomicroscopy. Cornea. 2008 Feb;27(2):180-188 Authors: Garcia JP, de la Cruz J, Rosen RB, Buxton DF PURPOSE:: To describe the anterior ocular segment findings of eyes with implanted Boston type 1 keratoprostheses (KPro) in vivo by using anterior-segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM). METHODS:: A retrospective, comparative study was made of patients with implanted KPros who were examined with AS-OCT (AC Cornea OCT) and UBM (OTI Scan 35-50MHz Ultrasound). RESULTS:: One pseudophakic and 1 aphakic eye were included in the study. Cross-sectional AS-OCT ...
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    4. Monitoring mouse retinal degeneration with high-resolution spectral-domain optical coherence tomography

      Progression of retinal degeneration in a mouse model was studied in vivo with high-resolution spectral-domain optical coherence tomography (SD-OCT). Imaging in 3D with high depth resolution (<3 μm), SD-OCT resolved all the major layers of the retina of control C57BL/6J mice. Images of transgenic mice having a null mutation of the rhodopsin gene revealed the anatomical consequences of retinal degeneration: thinning of the outer retina, including the outer plexiform layer (OPL), outer nuclear layer (ONL), and inner and outer segments (IS/OS). We monitored the progression of retinal degeneration in rd1 mice (C3H/HeJ) by periodically imaging the same ...
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    5. Application of optical coherence tomography in non-invasive characterization of skin vascular lesions

      Optical coherence tomography (OCT) is a new non-invasive approach for real-time in vivo tissue characterization. A promising use of OCT can be the assessment of the architecture of lesions with some degree of inhomogeneities, such as vascular lesions. Knowledge of the size and depth of the vascular structures can be useful for the diagnosis and for choosing the best treatment.
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    6. The Stress on the Anterior Lens Surface During Human in vivo Accommodation.

      Related Articles The Stress on the Anterior Lens Surface During Human in vivo Accommodation. Br J Ophthalmol. 2008 Jan 22; Authors: Schachar RA, Koivula A Purpose: To determine the qualitative change in stress on the lens capsule during in vivo human accommodation. Methods: Nine subjects [mean age: 30 years, range: 25-38 years] were studied, each of whom had undergone a phakic refractive intraocular lens (PRL) surgical procedure. The change, during accommodation, of stress on the surface of the anterior lens capsule (ALS) was determined by employing high-resolution anterior segment optical coherence tomography (OCT). This was done by comparing the ratio ...
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    7. Intravitreal avastin for macular edmema secondary to retinal vein occlusion - a prospective study.

      Related Articles Intravitreal avastin for macular edmema secondary to retinal vein occlusion - a prospective study. Br J Ophthalmol. 2008 Jan 22; Authors: Kriechbaum K, Michels S, Prager F, Georgopoulos M, Funk M, Geitzenauer W, Schmidt-Erfurth U Abstract OBJECTIVE: To evaluate efficacy and safety of intravitreal bevacizumab (Avastin) in eyes with macular edema secondary to central (CRVO) or branch retinal vein occlusion (BRVO). METHODS: Twenty-eight consecutive patients (28 patients, 29 eyes, 8 CRVO, 21 BRVO) were enrolled in the study. Three intravitreal injections of 1 mg bevacizumab (0.04 ml) were administered at 4 week intervals; further retreatment was based on ...
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    8. Correlation between intraretinal changes in diabetic macular oedema seen in fluorescein angiography and optical coherence tomography

      Abstract.Purpose: To study the relationship between intraretinal optical coherence tomography (OCT) and fluorescein angiography (FA) findings in eyes with diabetic macular oedema (DMO).Methods: We carried out a retrospective observational case series. ...

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    9. Consistency of ocular coherence tomography fast macular thickness mapping in diabetic diffuse macular edema.

      OBJECTIVES: To investigate optical coherence tomography consistency on foveal thickness, foveal volume, and macular volume measurements in patients with and without diffuse diabetic macular edema. INTRODUCTION: Optical coherence tomography represents an objective technique that provides cross-sectional tomographs of retinal structure in vivo. However, it is expected that poor fixation ability, as seen in diabetic macular edema, could alter its results. Several authors have discussed the reproducibility of optical coherence tomography, but only a few have addressed the topic with respect to diabetic maculopathy. METHODS: The study recruited diabetic patients without clinically evident retinopathy (control group) and with diffuse macular edema ...
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    10. Intravitreal Bevacizumab and Triamcinolone Acetonide Combination Therapy for Exudative Neovascular Age-Related Macular Degeneration: Short-Term Optical Coherence Tomography Results.

      Intravitreal Bevacizumab and Triamcinolone Acetonide Combination Therapy for Exudative Neovascular Age-Related Macular Degeneration: Short-Term Optical Coherence Tomography Results. J Ocul Pharmacol Ther. 2008 Jan 17; Authors: Colucciello M Purpose: The aim of this study to describe the short-term anatomical results after an intravitreal injection of bevacizumab and triamcinolone acetonide in patients with foveal edema and/or subfoveal fluid associated with neovascularization (NV) due to age-related macular degeneration (AMD). Methods: A retrospective, noncomparative case series was conducted in patients with foveal edema and/or subfoveal fluid associated with NV due to AMD during a 3-month period. Patients were treated with intravitreal ...
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    11. A preliminary study on intravitreal injection of bevacizumab for treatment of neovascular age-related macular degeneration.

      [A preliminary study on intravitreal injection of bevacizumab for treatment of neovascular age-related macular degeneration.] Zhonghua Yan Ke Za Zhi. 2007 Oct;43(10):890-6 Authors: Tang SB, Liang XL, Hu J, Ding XY, Wan T, Guo MX, Hu YQ OBJECTIVE: To evaluate the short-term safety of intravitreous bevacizumab (Avastin) and its effects on visual acuity (VA) and subfoveal choroidal neovascularization (CNV) in patients with neovascular age-related macular degeneration (ARMD). METHODS: Single-center, uncontrolled clinical study. Five ARMD patients (5 eyes) with subfoveal CNV and best-corrected VA (BCVA) less than 0.1 were participated. Patients were treated with an intraviterous injection ...
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    12. Unusual coexistence of bilateral keratoconus and optic disc pit: A case report.

      Unusual coexistence of bilateral keratoconus and optic disc pit: A case report. Eur J Ophthalmol. 2008 Jan-Feb;18(1):134-7 Authors: Fasciani R, Mosca L, Giannico ML, Legrottaglie EF, Balestrazzi E PURPOSE. To report the unknown coexistence of bilateral optic disc pit and keratoconus. METHODS. A 23-year-old man with bilateral keratoconus underwent complete ophthalmology screening, with an unexpected detection of undiagnosed optic disc pit in both eyes. Computerized corneal topography (CT), Orbscan, corneal pachometry, endothelial microscopy, and optical coherence tomography (OCT) examination were performed. RESULTS. The corneal CT showed a keratoconus pattern in both eyes, evolved in the right eye ...
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    13. OCT and muti-focal ERG findings in spontaneous closure of bilateral traumatic macular holes.

      OCT and muti-focal ERG findings in spontaneous closure of bilateral traumatic macular holes. Doc Ophthalmol. 2008 Jan 18; Authors: Chen H, Zhang M, Huang S, Wu D Purpose To report the spontaneous closure of bilateral traumatic macular holes in a young patient, followed up with optical coherence tomography (OCT), muti-focal electroretinogram (mfERG), and Humphrey visual field examination. Methods A 25-year-old male who suffered from bilateral blunt trauma to the eyes and developed traumatic macular holes was followed with ophthalmic examination, OCT, mfERG, and Humphrey visual field examination. Results The OCT results revealed spontaneous closure in both eyes 2 weeks after ...
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    14. Intravitreal pegaptanib sodium for Irvine-Gass syndrome.

      Intravitreal pegaptanib sodium for Irvine-Gass syndrome. Eur J Ophthalmol. 2008 Jan-Feb;18(1):138-41 Authors: Querques G, Iaculli C, Delle Noci N PURPOSE. To report the novel use of intravitreal pegaptanib sodium for the treatment of refractory cystoid macular edema (CME) following cataract extraction. METHODS. A 72-year-old man presented with decreased visual acuity in his right eye 8 months after uncomplicated phacoemulsification cataract extraction and intraocular lens implantation. His bestcorrected visual acuity (BCVA) was 20/125 in the affected eye, and fundus examination revealed CME despite 6 months of oral and topical indomethacin therapy. Fluorescein angiography (FA) showed leakage in ...

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    15. Optical coherence tomography findings of incomplete posterior vitreoschisis with vitreomacular traction syndrome and impending macular hole: A case report.

      Optical coherence tomography findings of incomplete posterior vitreoschisis with vitreomacular traction syndrome and impending macular hole: A case report. Eur J Ophthalmol. 2008 Jan-Feb;18(1):147-9 Authors: Figus M, Carpineto P, Romagnoli M, Ferretti C, Di Antonio L, Nardi M PURPOSE. Vitreomacular traction syndrome is a clinical entity characterized by partial posterior vitreous detachment in combination with persistent macular adherence. Recently, optical coherence tomography (OCT) allowed visualization of incomplete posterior vitreoschisis leading to vitreomacular traction. METHODS. The authors report on a 57-year-old woman with blurred vision in her left eye. RESULTS. OCT scan showed incomplete posterior vitreoschisis with vitreomacular ...
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    16. Analysis of progressive ophthalmic lesion in a patient with subacute sclerosing panencephalitis.

      PURPOSE. To evaluate the progressive lesions affecting the visual system in a patient with subacute sclerosing panencephalitis (SSPE). METHODS. The authors observed a 15-year-old boy with SSPE. Since the diagnosis was made before the appearance of ocular manifestations, the authors recorded the progressive ocular lesions using various ophthalmic examinations. RESULTS. The patient showed no ophthalmic abnormalities until he developed a left homonymous hemianopia with sudden bilateral disturbed visual acuity. Severe progressive macular lesions including a pigment epithelial window defect by fluorescein angiography, a marked decrease in foveal thickness by optical coherence tomography, and an extensive disorder mainly specific to cone ...

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    17. METHOD AND DEVICE FOR OPTICAL DETECTION OF THE EYE

      (WO/2008/000403) CARL ZEISS MEDITEC AG [DE/DE]; Göschwitzer Strasse 51-52, 07745 Jena (DE) (All Except US). RUSSMANN, Christoph [DE/DE]; Coppanzer Weg 4A, 07745 Jena (DE) (US Only). DICK, Manfred [DE/DE]; Birkenweg 9, 07926 Gefell (DE) (US Only). RUSSMANN, Christoph [DE/DE]; Coppanzer Weg 4A, 07745 Jena (DE). DICK, Manfred [DE/DE]; Birkenweg 9, 07926 Gefell (DE). Title: Abstract: The invention r
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    18. OCT and muti-focal ERG findings in spontaneous closure of bilateral traumatic macular holes

      Abstract   Purpose To report the spontaneous closure of bilateral traumatic macular holes in a young patient, followed up with optical coherence tomography (OCT), muti-focal electroretinogram (mfERG), and Humphrey visual field examination. Methods A 25-year-old male who suffered from bilateral blunt trauma to the eyes and developed traumatic macular holes was followed with ophthalmic examination, OCT, mfERG, and Humphrey visual field examination. Results The OCT results revealed spontaneous closure in both eyes 2 weeks after trauma, and the macular holes remained closed in the 7 months of follow-up. Visual acuity improved to 0.7 in right and 0.9 in left ...
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    19. Inexpensive OCT glaucoma assessment tool can track MS activity

      January 16, 2008, Buffalo, NY--New research by neurologists at the University at Buffalo has shown that optical coherence tomography (OCT) also could be used as a surrogate marker of disease status in multiple sclerosis (MS) and to assess the effectiveness of new and current MS treatments.
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    20. Activity of neovascular lesions treated with bevacizumab: comparison between optical coherence tomography and fluorescein angiography.

      PURPOSE: To investigate whether examination with the non-invasive optical coherence tomography (OCT) alone is sufficient to ascertain the need of re-treatment with bevacizumab for exudative age-related macular degeneration (AMD) or the invasive fluorescein angiography (FA) is needed. METHOD: Two independent examiners reviewed FA and OCT images and performed a semi-quantitative assessment from 0=no activity to activity 1-3, mild, moderate and advanced, respectively. Weighted Kappa indices were performed to calculate the concordance between OCT and FA. RESULTS: A total of 153 OCT and FA examinations of 69 patients were evaluated, mean 2.2 examinations per patient. The mean age was ...
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