1. Articles in category: Ophthalmology

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    1. Optical multiplex short coherence interferometry on the eye

      The invention is directed to the detection and imaging of the internal geometry of the eye, particularly of the important components for imaging in the eye such as the cornea, lens, vitreous body and retinal surface, by multichannel short coherence interferometry. A method and arrangement for obtaining topograms and tomograms of the eye structure by many simultaneously recorded interferometric depth scans through transversely adjacent points in the pupil using spatially coherent or spatially partially coherent light sources. The depth scan is carried out by changing the optical length of the interferometer measurement arm by means of a retroreflector. By continuously ...
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    2. Heidelberg Engineering Adds OCT Product Line

      Heidelberg Engineering Adds OCT Product Line

      DOSSENHEIM, Germany--June 6, 2005--Heidelberg Engineering GmbH announced today the purchase of assets of the company 4optics AG, Lubeck, Germany. The transaction adds optical coherence tomography (OCT) technology to its ophthalmic product offering. "Heidelberg Engineering has a wide range of expertise in laser scanning technology for diagnostic eye care. With this move, we are adding a well-qualified scientific team and additional products to our R&D pipeline," noted Dr. Gerhard Zinser, managing director and head of R&D for Heidelberg Engineering. "We now have command of the two most important technological innovations in diagnostic eye care.” The company will take over ...

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    3. Enhanced visualization of retinal pathologies with ultrahigh resolution optical coherence tomography (Thesis)

      Enhanced visualization of retinal pathologies with ultrahigh resolution optical coherence tomography (Thesis)
      Current clinical practice calls for the development of techniques to diagnose diseases in its early stages, when treatment is most effective and significant irreversible damage can either be prevented or delayed. Optical coherence tomography (OCT) is an emerging medical diagnostic technology being investigated for applications in a number of medical fields including ophthalmology, cardiology, and gastroenterology. OCT is analogous to ultrasound except that it uses light waves rather than sound waves. OCT can achieve a much higher resolution than ultrasound in measuring the underlying tissue microstructures. Another advantage of OCT is that it can achieve imaging in a non-contact and ...
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    4. Optical coherence tomography for retinal imaging (Thesis)

      Optical coherence tomography for retinal imaging (Thesis)
      In this thesis, two new imaging modalities are proposed for the early detection of glaucoma. Both modalities are based on optical coherence tomography, a technology that uses low-coherence light to create two-dimensional images of the retina. Depth scans are made as reflections are detected as a function of path length difference by rapidly changing the reference arm length of an interferometer. The sensitive coherence window that is created rejects light returning from other depths.
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    5. A Test Eye for Wavefront Eye Refractors

      A Test Eye for Wavefront Eye Refractors
      PURPOSE A multi-site study was conducted to test feasibility of a modified automatic refractor style test eye as a test device for wavefront refractors of various types and to determine whether a) they could be measured and b) when measurements could be made, to see if they were similar. This study did not attempt to assess which instrument most accurately measures the aberrations of the test eye or human eye. METHODS Three automatic refractor style test eyes were modified for use as test devices for wavefront refractors. One had a simple spherical front surface, and two had additional aberrations added ...
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    6. Atlas of Optical Coherence Tomography of Macular Diseases (Book)

      Atlas of Optical Coherence Tomography of Macular Diseases (Book)
      In real time, optical coherence tomography (OCT) provides high-resolution cross-sectional images of the macula very similar to those obtained by in vivo histopathological sections. OCT represents a major advance in the diagnostics of retinal disease and has found rapid acceptance among retinal specialists worldwide. OCT is not a substitute for a thorough clinical examination, fundus imaging or various angiographic techniques, but a superb adjunctive tool for probing the mysteries of retinal disease. Throughout this highly illustrated text of both normal and diseased appearances, OCT images are accompanied by fluorescein angiograms and standard fluoroscopic scans, thereby providing the reader with an ...
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    7. Three dimensional real-time image apparatus of ocular retina

      The disclosed content relates to a three dimensional real-time imaging apparatus of the ocular retina, which is associated with the most frequent ophthalmic diseases. In the present invention, the laser rays are formed into two dimensional ray surface sequentially with the time by using a polygon mirror motor and galvanometer and irradiated on the almost transparent retina through the pupil. The optical system is so arranged that the incident angles, relative to a retina, of the laser beams irradiated on the retina at respective moments may agree with the output angles of imaginary lines of the same laser rays reflected ...
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    8. Carl Zeiss Meditec to acquire Laser Diagnostic Technologies

      New Orleans—Carl Zeiss Meditec Inc. and Laser Diagnostic Technologies Inc. (LDT) announced that they have signed a definitive agreement for Carl Zeiss Meditec's acquisition of LDT. "This acquisition is another important milestone of our growth strategy," said Jim Taylor, president and chief executive officer of Carl Zeiss Meditec Inc. "It will further strengthen our technology portfolio and undisputed leadership in the growing market of glaucoma diagnosis and management. Looking forward, we will continue our aggressive growth through pursuit of both internal and external potentials." LDT President and CEO John Moore noted that this deal is a reflection of ...
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    9. Arrangements for coherence topographic ray tracing on the eye

      Topographic measurement of eye structures based on short coherence interferometry is the subject of the invention. The problem occurring in this connection is that longitudinal and transverse eye movements during signal registration lead to errors in the measured structure. The influences of longitudinal eye movements are compensated in that the reference beam, independent from the measurement beam, is directed to the corneal vertex and is reflected at the latter. The influences of longitudinal eye movements are minimized in that the transverse position of the eye is monitored by means of a direction-dependent registration of the light reflected at the corneal ...
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    10. System and method for non-contacting measurement of the eye

      Combined equipment for non-contacting determination of axial length (AL), anterior chamber depth (VKT) and corneal curvature (HHK) of the eye are also important for the selection of the intraocular lens IOL to be implanted, particularly the selection of an intraocular lens IOL to be implanted, preferably with fixation of the eye by means of a fixating lamp and/or illumination through light sources grouped eccentrically about the observation axis.
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    11. Optical mapping apparatus with adjustable depth resolution and multiple functionality

      The present invention relates to a multiple channel optical mapping apparatus which can deliver one or simultaneously at least two images of different depth resolutions or sequentially, images with different depth resolutions, or a combination of these images, or a single image with adjustable depth resolution. The multiple channels could be either multiple confocal channel and one or two optical coherence tomography channel, or two optical coherence tomography channels, or two confocal channels. The channels, either OCT or confocal can operate on the same wavelength or on different wavelengths. The apparatus can display both transversal as well as longitudinal images ...
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    12. Methods for measuring retinal damage

      Methods for measuring retinal damage resulting from an injury include calculating the slope of retinal thickness from the injury site to the periphery of the site. A shallower slope of retinal thickness correlates with a greater degree of damage resulting from the injury. The methods may also be useful to screen pharmaceuticals for potential neuroprotective effects against retinal injuries.
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    13. Method and device for the photoablation of the cornea with a laser beam

      In a method for photoablation on the cornea with a laser beam with the aid of which a multiplicity of consecutive partial ablation operations are undertaken, the thickness of the cornea is determined with the aid of a measuring device co-operating with a Michelson interferometer before and after each partial ablation operation. By using the thickness values determined, the measuring device guides the laser beam, with intensity values appropriately adjusted by it, over the cornea in a controlled fashion so as not to undershoot a prescribed cornea thickness while complying with a prescribed cornea profile. The measuring device operates with ...
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    14. Tracking assisted optical coherence tomography

      One embodiment of the present invention is an optical coherence tomography ("OCT") application apparatus that performs an OCT application on an object. The OCT application apparatus includes: (a) an OCT scanning apparatus which outputs a scanning beam of OCT scanning radiation; and (b) an active tracking system that generates and projects a tracking beam of tracking radiation onto a region including a reference tracking feature; wherein the active tracking system further includes an analysis system that analyzes tracking radiation reflected from the region to detect movement of the object and to generate tracking signals, and applies the tracking signals (i ...
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    15. Optical Coherence Tomography of Ocular Diseases, Second Edition (Book)

      Optical Coherence Tomography of Ocular Diseases, Second Edition (Book)
      Optical Coherence Tomography of Ocular Diseases, Second Edition is a completely revised and updated version of this classic text. Incorporated within over 700 pages are a multitude of updated features unique to this edition including over 1,600 color images, state-of-the-art technology, and case presentations. These elements cohesively work together to successfully demonstrate the retina in normal and diseased states using the innovative Stratus OCTTM. Optical Coherence Tomography of Ocular Diseases, Second Edition is written with the clinician in mind. The text's primary objective is to illustrate the appearance of the eye in health and disease, comparing conventional clinical ...
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    16. Method of manufacturing customized intraocular lenses

      A method of manufacturing an intraocular lens that has been customized to provide optimum vision for an eye with prior corneal refractive surgery. Such a custom manufactured IOL will address not only optical correction requirements as currently met by spherical or toric-shaped IOLs, but will correct higher order optical aberrations using needed optimum customized shapes.
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    17. Method and apparatus for the simultaneous determination of surface topometry and biometry of the eye

      An apparatus (10') for detecting the surface topography of a cornea (24) of an eye (22) by dynamic or static projection of a pattern onto the surface of the cornea and detection of the pattern reflected by the cornea, providing preferably simultaneous detection of at least one optical property of a layer disposed beneath the cornea.
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      Mentions: Adolf F. Fercher
    18. Method and device configuration for determining the corneal thickness of an eye

      Proposed is a method and a device configuration for determining the corneal thickness of an eye, in particular of a human eye, by means of light rays. First light rays are projected onto and into the cornea, and second light rays, reflected by the cornea, are registered for determining the corneal thickness. A contact element, which is preferably plane-parallel, is placed on the contact area of the cornea, and the first light rays are projected through the contact element onto and into the cornea. The contact element is fixed on the cornea, for example. The first light rays are projected ...
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    19. Optical coherence tomography: evaluation and clinical application (Thesis)

      Optical coherence tomography: evaluation and clinical application (Thesis)
      The ability to examine the appearance of the retina is of paramount importance for the diagnosis and monitoring of ophthalmic disease and for the evaluation of treatment outcomes. Direct cross-sectional imaging of retinal structure could be useful for early diagnosis and more sensitive monitoring of a variety of retinal conditions such as macular oedema and glaucoma. The view of the fundus given by ophthalmoscopy provides very limited depth information and clinicians will often have to resort to additional techniques such as flourescein angiography or visual field testing for information on structural abnormalities within the retina. Other currently available imaging techniques ...
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    20. Method and apparatus for improving vision and the resolution of retinal images

      A method of and apparatus for improving vision and the resolution of retinal images is described in which a point source produced on the retina of a living eye by a laser beam is reflected from the retina and received at a lenslet array of a Hartmann-Shack wavefront sensor such that each of the lenslets in the lenslet array forms an aerial image of the retinal point source on a CCD camera located adjacent to the lenslet array. The output signal from the CCD camera is acquired by a computer which processes the signal and produces a correction signal which ...

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    21. Nondestructive Quantification of Analyte Diffusion in Cornea and Sclera Using Optical Coherence Tomography

      PURPOSE. Noninvasive functional imaging, monitoring, and quantification of analytes transport in epithelial ocular tissues are extremely important for therapy and diagnostics of many eye diseases. In this study the authors investigated the capability of optical coherence tomography (OCT) for noninvasive monitoring and quantification of diffusion of different analytes in sclera and cornea of rabbit eyes. METHODS. A portable time-domain OCT system with wavelength of 1310 ± 15 nm, output power of 3.5 mW, and resolution of 25 µm was used in this study. Diffusion of different analytes was monitored and quantified in rabbit cornea and sclera of whole eyeballs. Diffusion ...
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    22. System and method for determining birefringence of anterior segment of a patient's eye

      The magnitude and axial orientation of birefringence of the anterior and the posterior segments of the human eye are determined. The anterior segment includes essentially the combined birefringence of the cornea and the crystalline lens, and the posterior segment includes regions at the fundus. The optical axis and the magnitude of the birefringence of the anterior segment is first determined, then the birefringence of the posterior segment is nulled by a variable retarder. The birefringence of the posterior segment is then determined without interference of the birefringence of the anterior segment. The apparatus and method are applicable to the measurement ...
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