1. Articles in category: Ophthalmology

    11113-11136 of 11369 « 1 2 ... 461 462 463 464 465 466 467 ... 472 473 474 »
    1. Intravitreal triamcinolone versus bevacizumab for treatment of refractory diabetic macular oedema (ibeme study)

      Background/aims: The aim of this study was to compare the morphological and visual acuity outcomes associated with a single intravitreal injection of triamcinolone acetonide versus bevacizumab for the treatment of refractory diffuse diabetic macular oedema. Methods: Twenty-eight patients were randomly assigned to receive a single intravitreal injection of either 4 mg/0.1 ml triamcinolone acetonide or 1.5 mg/0.06 ml bevacizumab. Comprehensive ophthalmic evaluation was performed at baseline and at weeks 1, 4, 8 (±1), 12 (±2) and 24 (±2) after treatment. Main outcome measures included central macular thickness measured with optical coherence tomography (OCT) and ...
      Read Full Article
    2. Trans-Tenon's retrobulbar triamcinolone acetonide injection for macular oedema related to branch retinal vein occlusion

      Background: The aim of the study was to evaluate the safety and effectiveness of trans-Tenon’s retrobulbar triamcinolone acetonide (TA) injection for macular oedema associated with branch retinal vein occlusion (BRVO). Methods: We reviewed the medical records of 50 consecutive patients with macular oedema associated with BRVO who were treated with trans-Tenon’s retrobulbar TA injection (20 mg) as initial treatment for a follow-up period of at least 12 months. Foveal thickness determined by optical coherence tomography, visual acuity, intraocular pressure (IOP) and cataract progression were measured. Results: The mean duration between oedema onset and TA injection was 4.9 ...
      Read Full Article
    3. Central visual field impairment during and following cystoid macular oedema

      Aim: To determine differential light threshold values obtained with the Micro Perimeter 1 (MP1) in uveitis patients suffering from cystoid macular oedema (CMO) and to compare these measures to retinal thickness. Methods: Static threshold perimetry was performed with the MP1 Microperimeter in 27 eyes of 21 patients with a history of chronically recurring CMO. Active CMO was confirmed in 19 eyes. Eight eyes with a history of recurrent CMO were found to have normal foveal contours in optical coherence tomography (OCT). Differential light threshold values (MP1) were compared with the corresponding retinal thickness measures (OCT). Results: Mean differential threshold values ...
      Read Full Article
    4. Degree of angle closure and extent of peripheral anterior synechiae: an anterior segment OCT study

      Aims: To evaluate the relationship between angle width as determined by anterior segment optical coherence tomography (AS-OCT) and the presence of peripheral anterior synechiae (PAS). Methods: This was a prospective observational case series in which 203 subjects with primary angle closure or open angles were recruited. Images of the nasal, temporal and inferior angles were obtained with AS-OCT in dark conditions. Subjects then underwent gonioscopy by an independent examiner who was masked to the AS-OCT findings. PAS were identified by gonioscopy and defined as abnormal adhesions of the iris to the angle that were at least half a clock hour ...
      Read Full Article
    5. Half-top-hat a new wound configuration for penetrating keratoplasty

      Aims: To describe a new, simpler method of achieving the advantages of a lamellar wound configuration in penetrating keratoplasty (PKP)—the half-top-hat (HTH) configuration. Methods: The donor corneal button was prepared in a top-hat configuration, as previously described. It consisted of a central, full-thickness part, 7–8 mm in diameter, surrounded by a peripheral lamellar wing of deep stroma and endothelium that was 0.5 mm in width (wing diameter 8–9 mm). The recipient bed was prepared by a straight full thickness trephination with a suction trephine. The donor button was positioned by sliding the peripheral wing under the ...
      Read Full Article
    6. Simultaneous imaging of human cone mosaic with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography

      M. Pircher, R. J. Zawadzki, J. W. Evans, J. S. Werner, C. K. Hitzenberger We describe a novel instrument capable of acquiring, simultaneously, adaptive optics enhanced scanning laser ophthalmoscopy and optical coherence tomography (OCT) images of the human cone mosaic in vivo. The OCT system is based on transversal scanning of the sample with a line scan rate of 14 kHz, ... [Opt. Lett. 33, 22-24 (2008)]
      Read Full Article
    7. Stratus OCT in Dominant Optic Atrophy: Features Differentiating it From Glaucoma.

      PURPOSE: To describe the Stratus optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) thickness profile of dominant optic atrophy (DOA), to differentiate it from that of glaucoma. METHODS: RNFL thickness was measured using Stratus OCT in 32 eyes of 16 DOA patients. RESULTS: The temporal-most clock hour measurement was outside the 95% normal limit in 29 of the 32 DOA eyes (90.6%). The pattern of RNFL damage was bilaterally symmetrical in location and severity in all subjects. CONCLUSION: Stratus OCT shows characteristic findings differentiating DOA from glaucoma. PMID: 18091450 [PubMed - in process]
      Read Full Article
    8. Inexpensive Glaucoma Assessment Tool Can Track MS Activity

      University at Buffalo Reporter - New research by neurologists at the University at Buffalo has shown that a technique called optical coherence tomography, or OCT, a simple and inexpensive measure employed currently to assess glaucoma, also could be used as a surrogate marker of ...
      Read Full Article
    9. Fourier domain optical coherence tomography with a linear-in-wavenumber spectrometer.

      Related Articles Fourier domain optical coherence tomography with a linear-in-wavenumber spectrometer. Opt Lett. 2007 Dec 15;32(24):3525-7 Authors: Hu Z, Rollins AM We describe Fourier domain optical coherence tomography equipped with a novel linear-in-wavenumber spectrometer. The presented device linearizes the spectral dispersion of the spectrometer in wavenumber using a specifically designed prism. The spectral linearity in wavenumber makes numerical interpolation into wavenumber unnecessary, reduces computing time, and furthermore results in improvement of the falloff of signal with image range inherent to frequency-domain optical coherence tomography imaging. Experiments demonstrate the improvement of the falloff and agree with the expected ...
      Read Full Article
    10. Correlation between retinal nerve fibre layer thickness and retinal sensitivity

      Purpose: To evaluate the relationship between retinal nerve fibre layer (RNFL) thickness measured by optical coherence tomography (OCT) and light threshold values obtained with the Micro Perimeter 1 (MP1). Methods: Forty-nine normal subjects and 37 glaucoma patients were included. Thickness of the RNFL around the optic disc was measured with Stratus OCT scans, and static threshold perimetry was performed with the MP1 at the same visit. Total average and mean 12-clock-hour RNFL thickness were measured with Stratus OCT. An automated 4-2-1 staircase strategy with Goldmann III stimuli was used for MP1. The correspondence between Stratus OCT and MP1 RNFL measurements ...
      Read Full Article
    11. Accuracy of cornea and lens biometry using anterior segment optical coherence tomography

      Mark C. M. Dunne, Leon N. Davies, and James S. Wolffsohn We assess the accuracy of the Visante anterior segment optical coherence tomographer (AS-OCT) and present improved formulas for measurement of surface curvature and axial separation. Measurements are made in physical model eyes. Accuracy is compared for measurements of corneal thickness (d) and ante ... [J. Biomed. Opt. 12, 064023 (2007)] published Tue Dec 18, 2007.
      Read Full Article
    12. Great Strides Moved MS Research Forward During 2007

      National Multiple Sclerosis Society Published: December 14, 2007 The year 2007 saw rapid research progress in the fields of science and medicine that impact our understanding of the unpredictable neurological disease multiple sclerosis. Thanks to its generous contributors, the National MS Society was able to invest over $46 million this year into over 440 new and ongoing MS research projects as part of its international effort to prevent, treat and cure MS. Significant advances have been made in
      Read Full Article
    13. Comparison of Optic Nerve Head Topography and Visual Field in Eyes with Open-angle and Angle-closure Glaucoma.

      Related Articles Comparison of Optic Nerve Head Topography and Visual Field in Eyes with Open-angle and Angle-closure Glaucoma. Ophthalmology. 2007 Dec 13; Authors: Boland MV, Zhang L, Broman AT, Jampel HD, Quigley HA OBJECTIVE: To compare the optic disc and visual field (VF) alterations in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). DESIGN: Observational case series. PARTICIPANTS: A total of 146 persons (217 eyes), 110 with POAG and 36 with PACG, recruited from a university glaucoma service. METHODS: Each subject underwent visual acuity measurement, applanation tonometry, gonioscopy, slit-lamp examination, dilated optic disc and retinal examination, axial eye length ...
      Read Full Article
    14. Chloroquine retinopathy: lipofuscin- and melanin-related fundus autofluorescence, optical coherence tomography and multifocal electroretinography.

      Related Articles Chloroquine retinopathy: lipofuscin- and melanin-related fundus autofluorescence, optical coherence tomography and multifocal electroretinography. Doc Ophthalmol. 2007 Dec 16; Authors: Kellner U, Kellner S, Weinitz S Purpose To evaluate melanin-related near-infrared fundus autofluorescence (NIA, excitation 787 nm, emission > 800 nm), lipofuscin-related fundus autofluorescence (FAF, excitation 488 nm, emission >500 nm), optical coherence tomography (OCT), and multifocal electroretinography (mfERG) in patients with chloroquine (CQ) retinopathy. Methods Two patients with progressed CQ retinopathy underwent clinical examination, ISCEV mfERG evaluation, and FAF and NIA imaging using a confocal scanning laser ophthalmoscope (Heidelberg Retina Angiograph 2) with either a 30 degrees or wide-angle ...
      Read Full Article
    15. Birefringence characterization of biological tissue by use of optical coherence tomography.

      Authors: Everett MJ, Schoenenberger K, Colston BW, Da Silva LB An improved polarization-sensitive optical coherence tomography (OCT) system is developed and used to measure birefringence in porcine myocardium tissue and produce two-dimensional birefringence mapping of the tissue. Signal-to-noise issues that cause systematic measurement errors are analyzed to determine the regime in which such measurements are accurate. The advantage of polarization-sensitive OCT systems over standard OCT systems in avoiding image artifacts caused by birefringence is also demonstrated. PMID: 18084468 [PubMed - in process]
      Read Full Article
    16. Monoclonal Antibodies: Recent findings in monoclonal antibodies described by researchers from Labbafinejad Medical Center

      Data detailed in 'Dramatic response of choroidal neovascularization associated with choroidal osteoma to the intravitreal injection of bevacizumab (Avastin)' have been presented. In this recent study, researchers in Iran conducted a study "To report the dramatic response of juxtafoveal choroidal neovascularization (CNV) associated with choroidal osteoma to a single intravitreal...
      Read Full Article
    17. Synthesized optical coherence tomography for imaging of scattering objects by use of a stepwise frequency-modulated tunable laser diode.

      Opt Lett. 1999 Nov 1;24(21):1502-4 Authors: He Z, Hotate K A technique named synthesized optical coherence tomography (SOCT) has been proposed and developed as an alternative method to the well-known optical coherence tomography for cross-sectional imaging of scattering objects. SOCT is based on the principle of synthesis of an optical coherence function by use of a tunable laser diode. With stepwise frequency modulation of light and synchronous phase modulation, the coherence function is synthesized into a peak at an arbitrary location. The longitudinal scattering distribution of the object under test is thus obtained without a mechanically driven ...
      Read Full Article
    18. Optimal interferometer designs for optical coherence tomography.

      Opt Lett. 1999 Nov 1;24(21):1484-6 Authors: Rollins AM, Izatt JA We introduce a family of power-conserving fiber-optic interferometer designs for low-coherence reflectometry that use optical circulators, unbalanced couplers, and (or) balanced heterodyne detection. Simple design equations for optimization of the signal-to-noise ratio of the interferometers are expressed in terms of relevant signal and noise sources and measurable system parameters. We use the equations to evaluate the expected performance of the new configurations compared with that of the standard Michelson interferometer that is commonly used in optical coherence tomography (OCT) systems. The analysis indicates that improved sensitivity is ...
      Read Full Article
    11113-11136 of 11369 « 1 2 ... 461 462 463 464 465 466 467 ... 472 473 474 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (7 articles) National Institutes of Health
    2. (4 articles) Oregon Health & Science University
    3. (3 articles) Sun Yat-Sen University
    4. (3 articles) Columbia University
    5. (2 articles) Johns Hopkins University
    6. (2 articles) Center for Ophthalmic Optics and Lasers
    7. (2 articles) University of British Columbia
    8. (2 articles) New York Eye and Ear Infirmary
    9. (2 articles) University of Coimbra
    10. (2 articles) Duke University
    11. (2 articles) Singapore Eye Research Institute
    12. (2 articles) University of São Paulo
  4. People in the News

    1. (3 articles) David Huang
    2. (2 articles) Peter A. Calabresi
    3. (2 articles) Jodhbir S. Mehta
    4. (2 articles) Richard B. Rosen
    5. (2 articles) Jay Wei
    6. (2 articles) Giuseppe Querques
    7. (1 articles) Robert Ritch
    8. (1 articles) Giovanni Gregori
    9. (1 articles) Philip J. Rosenfeld
    10. (1 articles) Sharon F. Freedman
    11. (1 articles) Ruikang K. Wang
    12. (1 articles) Jung-Yeul Kim
  5. OCT Companies in the News

    1. (7 articles) Carl Zeiss Meditec
    2. (5 articles) Optovue
    3. (2 articles) Topcon Medical Systems
    4. (2 articles) Heidelberg Engineering
    5. (1 articles) Leica
    6. (1 articles) Tomey Corporation
    7. (1 articles) LighTopTech
    8. (1 articles) LLTech
    9. (1 articles) Nidek
    10. (1 articles) Canon Medical Systems
    11. (1 articles) Bioptigen