1. Articles in category: Ophthalmology

    11089-11112 of 11751 « 1 2 ... 460 461 462 463 464 465 466 ... 488 489 490 »
    1. Glaucoma hype

      Regarding your July 15 article "Glaucoma becomes clear in device developed at Duke": Your article might make one think there is no other way to diagnose narrow-angle glaucoma. For decades a three-mirror lens has been used for gonioscopy to accurately diagnose narrow-angle glaucoma when used by a competent ophthalmologist. Additionally, optical coherence tomography has been available for many years to look at the angle created by the cornea and the iris. The Duke instrument is merely an adaptation of existing technology.
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    2. Quasi-simultaneous optical coherence tomography and confocal imaging

      Irina Trifanov, Michael Hughes, Adrian Gh. Podoleanu et al. A new approach of acquiring quasi-simultaneous optical coherence tomography (OCT) and confocal images is presented. The two images are generated using different principles, OCT and confocal microscopy. When the system is used to image the retina, the two images have depth resolutions, at present, of ... [J. Biomed. Opt. 13, 044015 (2008)] published Fri Jul 18, 2008.
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    3. Carl Zeiss Meditec Reaches 1,000 Cirrus HD-OCT Placements

      Most Advanced Optical Coherence Tomography System Achieves Record Adoption in Less Than One Year. Carl Zeiss Meditec, a leader in ophthalmic devices and surgical systems, today announced that it has installed the 1,000th Cirrus(TM) HD-OCT system at Pima Eye Institute in Tucson, Arizona. First introduced in November 2007, Cirrus HD-OCT has achieved broad acceptance in the ophthalmic industry and is rapidly becoming the standard of care for identifying retinal and glaucoma disease characteristics and for monitoring disease progression
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    4. Carl Zeiss Meditec Reaches 1000 Cirrus™ Hd-oct Placements

      Carl Zeiss Meditec, a leader in ophthalmic devices and surgical systems, today announced that it has installed the 1,000th Cirrus™ HD-OCT system at Pima Eye Institute in Tucson, Arizona. First introduced in November 2007, Cirrus HD-OCT has achieved broad acceptance in the ophthalmic industry and is rapidly becoming the standard of care for identifying retinal and glaucoma disease characteristics and for monitoring disease progression.
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    5. Predictors Of Anti-VEGF-ASSOCIATED Retinal Pigment Epithelial Tear Using Fa And Oct Analysis.

      PREDICTORS OF Anti-VEGF-ASSOCIATED RETINAL PIGMENT EPITHELIAL TEAR USING FA AND OCT ANALYSIS. Retina. 2008 Jul 14; Authors: Chiang A, Chang LK, Yu F, Sarraf D PURPOSE:: To identify fluorescein angiography and optical coherence tomography (OCT) predictors for retinal pigment epithelial (RPE) tear in eyes with pigment epithelium detachment (PED) associated with neovascular age-related macular degeneration treated with intravitreal vascular endothelial growth factor (VEGF) modulating therapy. DESIGN:: Retrospective comparative case series. METHODS:: In a single institutional center, 60 consecutive patients with PED and neovascular age-related macular degeneration treated with VEGF modulating therapy (either pegaptanib, bevacizumab, or ranibizumab) for more than a ...
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    6. In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography

      In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography
      Lin An, Ruikang K. Wang. Optical micro-angiography (OMAG), based on Fourier domain optical coherence tomography (OCT), is a recently developed imaging modality that provides dynamic blood flow imaging within microcirculation tissue beds in vivo. This paper presents its first application in imaging the blood circulations in ... [Opt. Express 16, 11438-11452 (2008)]
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    7. Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis.

      Related Articles Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis. Arch Neurol. 2008 Jul;65(7):924-928 Authors: Zaveri MS, Conger A, Salter A, Frohman TC, Galetta SL, Markowitz CE, Jacobs DA, Cutter GR, Ying GS, Maguire MG, Calabresi PA, Balcer LJ, Frohman EM BACKGROUND: Optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx) are similar yet provide information on different aspects of retinal nerve fiber layer (RNFL) structure (thickness values similar to histology for OCT vs birefringence of microtubules for GDx). OBJECTIVES: To compare the ability of ...
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    8. Foveolitis Associated with Dengue Fever: A Case Series

      Background: Dengue fever (DF), a viral infection caused by dengue virus, is characterized by fever, headache, muscle and joint pains. Approximately 50-100 million people are infected annually. Ocular manifestations during DF are uncommon and include intraretinal hemorrhages and cotton wool spots; manifestations predominantly characterized by foveal involvement have not been described before in DF or any other retinopathies. We describe the clinical features of a series of patients with DF-associated foveolitis. Methods: A retrospective review of patients with maculopathy associated with DF was conducted. Patients found to have a yellow-orange lesion at the fovea, supported by a typical optical coherence ...
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    9. Glaucoma becomes clear in device developed at Duke

      Glaucoma becomes clear in device developed at Duke
      For eight years Sandra Naylor went to one eye doctor after another, but none could explain why, exactly, her vision was blurry. It wasn't until she was referred to Dr. Sanjay Asrani, a Duke University glaucoma specialist, that Naylor learned she had an unusual form of glaucoma -- one that could cause her suddenly to lose part of her eyesight. Not so long ago, Asrani wouldn't have been able to diagnose her, either. But now, because of his curiosity and the skills of a colleague, he has a one-of-a-kind instrument that can catch an aggressive type of glaucoma that ...
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    10. Optical coherence tomography for eye-length measurement

      TECHNICAL FIELD OF THE INVENTIONThe present invention relates to optical techniques useful for measuring dimensions of a moveable living sample such as a human eye.BACKGROUNDIn industrial, medical, and various other applications, it often is necessary to make measurements at a resolution of less than 10 microns. This becomes especially difficult for samples, such as living samples, that are likely to move during themeasurement(s). A particular problem arises when measuring dimensions of the eye,
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    11. Evaluation of the Effect of Aging on Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography

      Purpose: To evaluate the relationship between age and retinal nerve fiber layer (RNFL) thickness in normal subjects, as measured by optical coherence tomography (OCT). Methods: One hundred and forty-four normal subjects (144 eyes), ranging from 16 to 84 years of age, were enrolled in this cross-sectional study. The RNFL thickness was determined using OCT with three circle scans 3.4 mm in diameter. Results: The average RNFL thickness was inversely correlated with age (r = -0.348, p
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    12. Retinal Nerve Fiber Layer in the Temporal Quadrant is Thinner in Migraine Patients

      Retinal Nerve Fiber Layer in the Temporal Quadrant is Thinner in Migraine Patients
      Retinal Nerve Fiber Layer in the Temporal Quadrant is Thinner in Migraine Patients A study (1) was conducted to compare the retinal nerve fiber layer thickness (RNFL) in eyes of migraine patients with age-matched healthy subjects using optical coherence tomography. The paper will be soon published in The British journal of ophthalmology. The migraine group and the control group's age was approximately between 20 and 36 years old. The migraine patients, with or without aura, were chosen accordin
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    13. Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis

      Background Optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx) are similar yet provide information on different aspects of retinal nerve fiber layer (RNFL) structure (thickness values similar to histology for OCT vs birefringence of microtubules for GDx). Objectives To compare the ability of OCT and GDx to distinguish eyes of patients with multiple sclerosis (MS) from eyes of disease-free controls and thus identify RNFL abnormalities. We also sought to examine the capacity of these techniques to distinguish MS eyes from those without a history of optic neuritis and to correlate with visual function. Design Cross-sectional ...

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    14. Optical Coherence Tomography in Neuromyelitis Optica

      Background  Neuromyelitis optica (NMO) is an inflammatory disease with combined features of optic neuritis and myelitis. This pathologic entity may induce severe disability, including visual loss and paraplegia. Other than clinical follow-up, there is no marker for severity of the disease. Objectives  To evaluate the use of optical coherence tomography (OCT) in NMO and to determine whether this new technique could be a good marker of axonal loss in NMO. Design  Cross-sectional study. Participants  Thirty-five patients with NMO or at a high risk for NMO (having optic neuritis or myelitis and who are positive for NMO antibody) were prospectively studied ...
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    15. The relationship between Rarebit perimetry and OCT-derived retinal nerve fibre layer thickness in glaucoma.

      The relationship between Rarebit perimetry and OCT-derived retinal nerve fibre layer thickness in glaucoma. Acta Ophthalmol. 2008 Jun 19; Authors: Katsanos A, Labiris G, Fanariotis M, Tsirouki T, Chatzoulis D Purpose: To examine the association between measures of neuroretinal matrix integrity as determined with Rarebit perimetry and optical coherence tomography (OCT)-derived retinal nerve fibre layer thickness. Methods: One randomly selected eye of 30 White primary open-angle glaucoma patients (age: 60.9 +/- 11.7 years; MD: -3.2 +/- 5.1 dB) and 16 healthy White individuals (age: 33.2 +/- 6.4 years; MD: -0.8 +/- 0.8 dB) were included ...
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    16. Retinal peripapillary nerve fiber layer thickness in neuromyelitis optica.

      Retinal peripapillary nerve fiber layer thickness in neuromyelitis optica. Invest Ophthalmol Vis Sci. 2008 Jul 9; Authors: Merle H, Olindo S, Donnio A, Richer R, Smadja D, Cabre P Purpose: Measure the thickness of retinal peripapillary nerve fibers throughout the course of neuromyelitis optica (NMO). Design: Cross-sectional study. Methods: The thickness of the layer of retinal peripapillary nerve fibers was measured in optical coherence tomography with the Stratus OCT (Optical Coherence Tomography, Carl Zeiss Meditec Inc., Dublin, California, USA), equipped with the 4.0 version of the software. The results were acquired according to protocol with the fast RNFL (Retinal ...
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    17. Reorganization of photoreceptor layer on optical coherence tomography concurrent with visual improvement after macular hole surgery.

      To report three cases in which reorganization of the photoreceptor layer on optical coherence tomography (OCT) was concurrent with long-term visual recovery after macular hole surgery. Serial OCT scans of three eyes in which visual acuity continued to improve for 1 or more years after successful macular hole surgery were reviewed. Case 1. At postoperative four weeks, visual acuity was 20/100 with disorganized photoreceptor layer on OCT. The photoreceptor layer had been reorganized and visual acuity had improved to 20/25 by 1 year. Case 2. Two weeks after the operation, visual acuity was 20/125 and disorganization of ...

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    18. Quantitative Analysis of Anterior Segment Optical Coherence Tomography Images: the Zhongshan Angle Assessment Program

      Purpose: To describe a new image analysis method and software for anterior chamber images obtained by the anterior-segment optical coherence tomography (AS-OCT).and to assess its intraobserver and interobserver measurement reproducibility. Methods: Twenty 8-bit grayscale 600 x 300 AS-OCT images with apparent wide angles and twenty images with apparent narrow angles were consecutively selected from a database. Two glaucoma fellowship-trained ophthalmologists used proprietary image analysis software to analyze the images twice. Algorithms defined the borders and curvatures of anterior chamber (AC) structures and measured AC parameters using scleral spur location as the only observer input. Intraobserver and interobserver reproducibility of ...
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    19. Ultrahigh resolution optical coherence tomography and pancorrection for cellular imaging of the living human retina

      Cellular in vivo visualization of the three dimensional architecture of individual human foveal cone photoreceptors is demonstrated by combining ultrahigh resolution optical coherence tomography and a novel adaptive optics modality. Isotropic resolution in the order of 2-3µm, estimated from ... [Opt. Express 16, 11083-11094 (2008)]

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    20. Long-Term Follow-up With Optical Coherence Tomography.

      Spontaneous resolution of a full-thickness macular hole occurs infrequently. This brief report documents a 2-year follow-up with optical coherence tomography (OCT) of an idiopathic full-thickness stage III macular hole resolving spontaneously, which to our knowledge is the longest follow-up with OCT in a case of spontaneous macular hole closure. This report adds to our understanding of the potential mechanisms of spontaneous closure in macular holes.Page: 225DOI: 10.1097/ICB.0b013e31809ed990Authors: Chen, Jennifer BAppSc(Optom)(Hons), PhD *+; Lee, Lawrence MB, BS, FRANZCO, FRACS *++; Vorster, Stephni BAppSc(Optom) +
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