1. Articles in category: Ophthalmology

    73-96 of 11652 « 1 2 3 4 5 6 7 ... 484 485 486 »
    1. Image processing apparatus, estimation method, system, and medium

      Image processing apparatus, estimation method, system, and medium

      The position of the fovea is estimated with high accuracy in a manner such that the thicknesses of a first region including at least a partial region of a region from the internal limiting membrane to the boundary between the external plexiform layer and the external granular layer and a second region including at least a partial region of a region from the boundary to the photoreceptor cell inner segment/outer segment junction are compared with each other, and the position of the fovea is estimated.

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    2. New England College of Optometry Professor Releases OCT Visual Atlas app – OCTaVIA

      New England College of Optometry Professor Releases OCT Visual Atlas app – OCTaVIA

      OCTaVIA, a visual reference OCT app, is now available free to eye care professionals and optometry/ophthalmology students of all levels on the Apple App Store. The iOS Optical Coherence Tomography (OCT) app was developed by Dr. Elena Z Biffi, Assistant Professor, New England College of Optometry (NECO) and attending optometrist at South Boston Community Health Center to assist in the diagnosis and management of retinal disorders in their daily practice. Dr. Biffi notes, “There is an urgent need in education and clinical practice for a dedicated smartphone/tablet app that can present a well-annotated OCT images for multiple diseases ...

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    3. Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

      Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

      Disclosed herein are methods and systems for the identification and characterization of fluid accumulation in the retina using OCT imaging. The disclosed methods and systems are directed to the automated segmentation of retinal fluid using 2D or 3D structural OCT scan images. Approaches for visualization and quantification of both intraretinal and subretinal fluid are presented. Methods are also disclosed for using OCT angiography data to improve the quality of retinal fluid segmentation, and to provide combined visualization of fluid accumulation and retinal vasculature to inform clinical interpretation of results.

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    4. Prof. Susana Marcos awarded Ramon y Cajal Medal by the Royal Academy of Sciences

      Prof. Susana Marcos awarded Ramon y Cajal Medal by the Royal Academy of Sciences

      The Royal Academy of Sciences, gathered in extraordinary plenary session on March 27, agreed to award the Ramón y Cajal Medal 2019, which rewards the trajectory of Spanish scientists under 50, to Prof. Susana Marcos. The jury of the award pointed that Prof. Marcos “has maintained an outstanding scientific career at an international level, with a fully multidisciplinary research program, using concepts of physics, optics, biology, biomechanics, ophthalmology and neuroscience to understand the basic mechanisms of human vision, develop diagnostic tools in ophthalmology and to invent new optical solutions for the correction of the most common vision problems. His ...

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    5. Iridocorneal angle assessment of companion rabbits using gonioscopy, spectral‐domain optical coherence tomography (Optovue iVue®), high‐resolution ultrasound, and Pentacam® HR imaging

      Iridocorneal angle assessment of companion rabbits using gonioscopy, spectral‐domain optical coherence tomography (Optovue iVue®), high‐resolution ultrasound, and Pentacam® HR imaging

      Objective Iridocorneal angle (ICA) narrowing is a known risk factor for primary glaucoma in multiple species, but has not been described in companion rabbits. This study aimed to develop an ICA grading scheme for companion rabbits to enable early glaucoma predisposition diagnosis. Animals studied Twenty healthy rabbits of varying breeds and ages. Procedures Rabbits received complete ophthalmic examinations, including gonioscopy, and imaging of the ICA using spectral‐domain optical coherence tomography (SD‐OCT), Scheimpflug imaging (Pentacam ® HR), and high‐resolution ultrasound (HRUS). Angle opening distance (AOD) and angle recess area (ARA) of the ICA were measured and assessed for agreement ...

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      Mentions: Optovue
    6. Inner Retinal Layer and Outer Retinal Layer Findings after Macular Hole Surgery Assessed by means of Optical Coherence Tomography

      Inner Retinal Layer and Outer Retinal Layer Findings after Macular Hole Surgery Assessed by means of Optical Coherence Tomography

      Aim . To summarize the spectrum of optical coherence tomography (OCT) and OCT angiography (OCTA) features after full-thickness macular hole (MH) repair surgery. Methods . A PubMed engine search was carried out using the terms “Macular Hole,” “Optical Coherence Tomography,” and “Optical Coherence Tomography Angiography.” All reports published in English up to October 2018, irrespective of their publication status, were included. Tomographic signs analyzed were divided according to the involved portion of the retina in “inner retinal layers” and “external retinal layers.” Despite predominantly involving the inner retinal layers, cystoid macular edema (CME) has been treated as a separate entity. Finally, report ...

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    7. Projection-Resolved Optical Coherence Tomography Angiography Parameters to Determine Severity in Diabetic Retinopathy

      Projection-Resolved Optical Coherence Tomography Angiography Parameters to Determine Severity in Diabetic Retinopathy

      Purpose : The purpose of this study was to assess projection-resolved optical coherence tomography angiography (PR-OCTA) vessel density (VD) and foveal avascular zone (FAZ) in determining severity within diabetic retinopathy (DR) and their accuracy in identifying high-risk DR patients. Methods : This was a retrospective study with 72 eyes of 52 DR patients, assessing the VD and FAZ area of the superficial capillary plexus (SCP) and deep vascular plexus (DVP), for both 3 × 3-mm and 6 × 6-mm scans between the DR groups (mild to moderate, severe and proliferative DR [PDR]). For accuracy, the severe and PDR groups were merged, representing the high-risk ...

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    8. Optical coherence tomography evidence of macular ganglion cell-inner plexiform layer thinning in eyes with subretinal drusenoid deposits

      Optical coherence tomography evidence of macular ganglion cell-inner plexiform layer thinning in eyes with subretinal drusenoid deposits

      Background/Objectives The purpose of this study was to evaluate macular ganglion cell layer-inner plexiform layer (GCL-IPL) and choroidal thickness in early age-related macular degeneration (AMD) in eyes with subretinal drusenoid deposits (SDD). Subjects/Methods Comprehensive ophthalmological examination was performed. Near infrared reflectance and raster images using enhanced depth imaging were acquired with spectral domain optical coherence tomography. Drusen and SDD were diagnosed based on raster scans and near infrared reflectance. GCL-IPL maps were generated with automated segmentation and choroidal thickness maps were obtained by manually delineating the choroid-scleral boundary. Results Forty-eight eyes from 48 patients (mean age 77.5 ...

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    9. PhD Studentship in Biomedical Optics and Retinal Imaging at The University of Illinois at Chicago

      PhD Studentship in Biomedical Optics and Retinal Imaging at The University of Illinois at Chicago

      A PhD position is available in the Biomedical Optics and Functional Imaging group within the Department of Bioengineering, University of Illinois at Chicago. Our research lab is working on ultra-wide field fundus photography, functional optical coherence tomography (OCT), OCT angiography (OCTA), super-resolution ophthalmoscopy, retinal image analysis and classification ( https://yaolab.bioe.uic.edu/ ). The PhD student will be involved for imaging instrument development and/or experimental study of retinal morphology & physiology. The specific study plan of the student can be flexible based on his/her education background and interest. The successful candidate should have a BS/MS degree in Optical ...

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      Mentions: Xincheng Yao
    10. Foveal and parafoveal choroidal thickness pattern measuring by swept source optical coherence tomography

      Foveal and parafoveal choroidal thickness pattern measuring by swept source optical coherence tomography

      Objective To evaluate the choroidal thickness (CT) in foveal and parafoveal regions in Thai adults using swept-source optical coherence tomography (SS-OCT). Methods We enrolled healthy volunteers ≥18 years of age from King Chulalongkorn Memorial Hospital, Thailand, during September 2015 to March 2016. Optical coherence tomography (OCT) of the macula was performed, and subfoveal CT was measured manually using a line scan. Average thicknesses of retinal and choroidal layers in regions of the Early Treatment Diabetic Retinopathy Study grid were measured automatically. A multivariate analysis was conducted to determine correlations between CTs in the foveal and parafoveal regions and retinal layers ...

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    11. Spectral domain optical coherence tomography with sub-micrometer sensitivity for measurement of central corneal thickness

      Spectral domain optical coherence tomography with sub-micrometer sensitivity for measurement of central corneal thickness

      We demonstrated a method for measurement of central corneal thickness (CCT) with a sub-micrometer sensitivity using a spectral domain optical coherence tomography system without needing a super broad bandwidth light source. By combining the frequency and phase components of Fourier transform, the method is capable of measurement of a large dynamic range with a high sensitivity. Absolute phases are retrieved by comparing the correlations between the detected and simulated interference fringes. The phase unwrapping ability of the present method was quantitatively tested by measuring the displacement of a piezo linear stage. The human CCTs of six volunteers were measured to ...

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      Mentions: Yi Wang
    12. Weakly supervised lesion localization for age-related macular degeneration detection using optical coherence tomography images

      Weakly supervised lesion localization for age-related macular degeneration detection using optical coherence tomography images

      Age-related macular degeneration (AMD) is the main cause of irreversible blindness among the elderly and require early diagnosis to prevent vision loss, and careful treatment is essential. Optical coherence tomography (OCT), the most commonly used imaging method in the retinal area for the diagnosis of AMD, is usually interpreted by a clinician, and OCT can help diagnose disease on the basis of the relevant diagnostic criteria, but these judgments can be somewhat subjective. We propose an algorithm for the detection of AMD based on a weakly supervised convolutional neural network (CNN) model to support computer-aided diagnosis (CAD) system. Our main ...

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      Mentions: Samsung
    13. Optical Coherence Tomography Angiography for Evaluation of Reperfusion following Pterygium Surgery

      Optical Coherence Tomography Angiography for Evaluation of Reperfusion following Pterygium Surgery

      Purpose To describe the use of optical coherence tomography angiography (OCTA) to quantitatively monitor the conjunctival graft revascularization after pterygium excision and conjunctival autograft (CAG) transplantation. Design Prospective, interventional case series. Methods Ten patients undergoing pterygium excision and femtosecond laser-assisted CAG transplantation were included. OCTA was performed at 1 week, 1 and 3 months postoperatively at the CAG transplantation site and harvested area. The vessel density at three different depths: conjunctival epithelium or CAG epithelium, conjunctival stroma or CAG stroma, and episclera, was evaluated and quantified. The revascularization rate was assessed and correlated with the postoperative CAG thickness. Results No ...

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    14. Detecting eye and brain disease earlier

      Detecting eye and brain disease earlier

      The eyes may be the window to the soul, but to scientists, they are also the window to the brain. In particular, the retina, a delicate light-sensing neural network with specialized cells at the back of the eyeball, is linked directly to the brain via the optic nerve and is considered by some to be part of the brain itself. Xincheng Yao (Photo: Jenny Fontaine) Now, researchers at the University of Illinois at Chicago are developing imaging techniques that will allow them to study minute changes in the retina that indicate the early stages of brain diseases like Alzheimer’s ...

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      Mentions: Xincheng Yao
    15. Parafoveal vessel loss and correlation between peripapillary vessel density and cognitive performance in amnestic mild cognitive impairment and early Alzheimer’s Disease on optical coherence tomography angiography

      Parafoveal vessel loss and correlation between peripapillary vessel density and cognitive performance in amnestic mild cognitive impairment and early Alzheimer’s Disease on optical coherence tomography angiography

      Purpose Patients with Alzheimer’s Disease (AD) exhibit decreased retinal blood flow and vessel density (VD). However, it is not known whether these changes are also present in individuals with early AD (eAD) or amnestic type mild cognitive impairment (aMCI), an enriched pre-AD population with a higher risk for progressing to dementia. We performed a prospective case-control clinical study to investigate whether optical coherence tomography angiography (OCTA) parameters in the macula and disc are altered in those with aMCI and eAD. Methods This is a single center study of 32 participants. Individuals with aMCI/eAD (n = 16) were 1:1 ...

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    16. A CARE-compliant article optical coherence tomography for epithelial basement membrane dystrophy A case report

      A CARE-compliant article optical coherence tomography for epithelial basement membrane dystrophy A case report

      Rationale: The etiology of anterior corneal opacities and the effect of debridement cannot be determined by biomicroscopy. Optical coherence tomography (OCT) helps identify the character and depth of these lesions. Patient concerns: A 45-year-old female complained of progressive blurred vision for a long time. Slit lamp biomicroscopy showed irregular, faint scar-like opacity of anterior cornea in her both eyes. Pentacam Scheimpflug camera tomography showed irregular astigmatism of anterior corneal surface. Anterior segment spectral-domain OCT revealed thickened, hyper-reflective linings, and scattered lesions, mainly in the epithelial layer. Diagnoses: Epithelial basement membrane dystrophy (EBMD). Intervention: Epithelial debridement and bandage lenses. Outcomes: The ...

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    17. Association Between Parapapillary Choroidal Vessel Density Measured With Optical Coherence Tomography Angiography and Future Visual Field Progression in Patients With Glaucoma

      Association Between Parapapillary Choroidal Vessel Density Measured With Optical Coherence Tomography Angiography and Future Visual Field Progression in Patients With Glaucoma

      Importance Investigating the vascular risk factors of glaucoma progression is important to individualize treatment; however, few studies have investigated these factors because the available methods have proven insufficient to evaluate the vascular features of patients with glaucoma. Recently, the advent of optical coherence tomography angiography (OCT-A) allowed both qualitative and quantitative microvascular data to be obtained, to in turn evaluate the perfusion status of different retinal layers. Objective To determine whether baseline parapapillary choroidal vessel density (VD) as measured by OCT-A was associated with future glaucoma progression. Design, Setting, and Participants A prospective, observational, comparative study was conducted at Seoul ...

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    18. Intra- and Interdevice Deviation of Optical Coherence Tomography Angiography

      Intra- and Interdevice Deviation of Optical Coherence Tomography Angiography

      Purpose To compare 4 optical coherence tomography-angiography (OCT-A) devices for foveal avascular zone (FAZ) measurements in healthy subjects. Methods The central retinas of 24 eyes of 12 healthy subjects were scanned with 4 different OCT-A devices (Optovue RTVue-XR, Zeiss Cirrus 5000-HD-OCT, a prototype Spectralis OCT2, Heidelberg Engineering, and Topcon DRI-OCT Triton Swept-source OCT). For the Topcon, Zeiss, and Optovue devices, 3-mm and 6-mm scans were performed. The Heidelberg device only provided 4-mm scans. En-face OCT-A images of the superficial and deep capillary plexus of the macular area were generated. The FAZ areas were measured and compared. Results Twenty-four healthy eyes ...

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    19. Retinal pathology on optical coherence tomography among eyes of older adults judged normal by color fundus photography

      Retinal pathology on optical coherence tomography among eyes of older adults judged normal by color fundus photography

      Purpose Optical coherence tomography (OCT) has revealed many details of retinal disease that were not available with older imaging technologies. In eyes of adults >60 years old with normal maculas as determined by color fundus photography (CFP) and a validated grading system, we screened for pathology using OCT. We also tested visual functions to assess potential impact of the observed pathologies on patients. Design cross-sectional study Participants This study recruited persons from primary ophthalmology care clinics. METHODS: CFP were assessed by the 9-step AREDS scale. OCT macular volumes of participants at step 1 on the AREDS scale, considered normal, were ...

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    20. Comparison of Spectralis and Cirrus spectral domain optical coherence tomography for the objective morphometric assessment of the neuroretinal rim width

      Comparison of Spectralis and Cirrus spectral domain optical coherence tomography for the objective morphometric assessment of the neuroretinal rim width

      Purpose The assessment of cup-disc ratio as a surrogate parameter for the neuroretinal rim width (NRW) of the optic nerve is well established, but prone to human error and imprecision. Objective assessment of the NRW is provided by spectral domain optical coherence tomography (SD-OCT). This study is the first to systematically compare NRW measurements acquired with the Carl Zeiss Meditech Cirrus HD-OCT 5000 and the Heidelberg Engineering Spectralis SD-OCT. Methods In this cross-sectional study, 20 eyes of each 20 glaucoma patients and 20 age-matched healthy controls underwent ophthalmic examination, SD-OCT imaging, and computer perimetry. Regression analyses were performed for the ...

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    21. Scattering-Angle-Resolved Optical Coherence Tomography of a Hypoxic Mouse Retina Model

      Scattering-Angle-Resolved Optical Coherence Tomography of a Hypoxic Mouse Retina Model

      Several studies have noted a correlation between retinal degeneration and traumatic encephalopathy (TE) making the retina a leading candidate for detection and assessment. Scattering-angle-resolved optical coherence tomography (SAR-OCT) is a candidate imaging modality to detect sub-resolution changes in retinal microstructure. SAR-OCT images of murine retinas that experience a hypoxic insult— euthanasia by isoflurane overdose—are presented. A total of 4 SAR-OCT measurement parameters are reported in 6 longitudinal experiments: blood flow volume fraction, total retinal thickness, reflectance index, and scattering angle. As each mouse expires, blood flow volume fraction decreases, total retinal thickness increases, reflectance index decreases, and scattering angle ...

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    22. Differences in retinal nerve fiber layer thickness measured by spectral domain optical coherence tomography between primary congenital glaucoma patients and healthy children

      Differences in retinal nerve fiber layer thickness measured by spectral domain optical coherence tomography between primary congenital glaucoma patients and healthy children

      Purpose To evaluate the retinal nerve fiber layer (RNFL) thickness using spectral domain optical coherence tomography (SD-OCT) in a population of children diagnosed with primary congenital glaucoma (PCG). Methods Cross-sectional study where 59 eyes from 59 children diagnosed with PCG and 87 eyes from 87 healthy children were evaluated by SD-OCT to measure the RNFL. The global average peripapillary RNFL thickness and sectional RNFL thickness were evaluated in both groups. Differences in global average and sectional thickness were analysed. Results Mean age in PCG group was 9.61±3.23 years old and in control groups was 8.47±2 ...

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    23. Optical coherence tomography for measurement on the retina

      Optical coherence tomography for measurement on the retina

      An optical coherence tomograph that provides wavelength tunable source radiation and an illumination and measurement beam path, a dividing element that divides source radiation into illumination radiation and reference radiation, and collects measurement radiation. The illumination and measurement beam path has scanner. A detection beam path receives measurement radiation and reference radiation and conducts them onto at least one flat panel detector in a superposed manner. A beam splitter separates the measurement radiation from the illumination radiation. The beam splitter conducts the separated measurement radiation to the detection beam path and sets the numerical aperture of the illumination of the ...

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    73-96 of 11652 « 1 2 3 4 5 6 7 ... 484 485 486 »
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