1. Articles in category: Ophthalmology

    553-576 of 9669 « 1 2 ... 21 22 23 24 25 26 27 ... 401 402 403 »
    1. Spectral Domain Optical Coherence Tomography (SD-OCT) Findings in Refsumʼs Disease

      Spectral Domain Optical Coherence Tomography (SD-OCT) Findings in Refsumʼs Disease

      Refsumʼs disease (OMIM 266500) is a very rare (about 60 cases have been reported worldwide) autosomal recessive inherited peroxisomal error of lipid metabolism with impaired alpha-oxidation of branched fatty acids that leads to an accumulation of phytanic acid in tissues and plasma [ 1 ]. Various mutations of genes like PEX7 (encodes PTS2 receptor) or PHYH (encodes phytanoyl-CoA hydroxylase) are associated with Refsumʼs disease. Most cases are detected by the clinical manifestations in the early childhood. Typical clinical signs are retinitis pigmentosa, cerebellar ataxia and peripheral neuropathy. Other symptoms are acustic nerve deafness, cardiomyopathy, cutaneous ichthyosis, and epiphysial dysplasia [ 2 ], [ 3 ]. Patients ...

      Read Full Article
    2. Optical coherence tomography of the Kayser-Fleischer ring: an ancillary diagnostic tool for Wilsons disease in children

      Optical coherence tomography of the Kayser-Fleischer ring: an ancillary diagnostic tool for Wilsons disease in children

      This report presents anterior segment optical coherence tomography (AS-OCT) images of Kayser-Fleischer ring (KFR) in a child. The AS-OCT images highlight differential reflectivity of the KFR depending on amount of copper deposited in cornea, thus supporting the role of AS-OCT as a follow-up tool. Utility of AS-OCT for diagnosing and documenting the KFR in children otherwise uncooperative for detailed slit lamp examination is discussed.

      Read Full Article
    3. Pioneering HD updates launched for the AngioVue OCT-A system

      Pioneering HD updates launched for the AngioVue OCT-A system

      Haag-Streit UK (HS-UK), the leading manufacturer and distributor of gold-standard optometry and ophthalmic equipment, is pleased to announce the launch of AngioVueHD imaging. This high density OCT Angiography (OCT-A) imaging will provide significant improvement in the resolution and peripheral visualisation of vasculature in the eye. AngioVue HD imaging provides OCT-A scans with 73% more sampling points, providing the user with a 6mm x 6mm scan with outstanding resolution. It also improves image resolution by approximately 33% over the existing field-of-view. The improvements enable physicians to more closely assess the fine vasculature in the eye for changes which could indicate ocular ...

      Read Full Article
      Mentions: Optovue Haag-Streit
    4. Relationship between internal reflectivity of diabetic microaneurysms on SD-OCT and detection on OCT Angiography

      Relationship between internal reflectivity of diabetic microaneurysms on SD-OCT and detection on OCT Angiography

      Purpose To correlate the appearance of Microaneurysms (MAs) on structural spectral-domain optical coherence tomography (SD-OCT) with their detection on OCT angiography (OCTA) in patients with non-proliferative diabetic retinopathy (NPDR). Design Inter-instrument reliability study. Methods Sixteen patients with NPDR without macular edema underwent SD-OCT and OCTA. To compare MAs seen on OCTA to those on SD-OCT, we superimposed the OCTA superficial capillary plexus (SCP) vascular landmarks onto those of the near infrared. Two observers blinded to patient groupings evaluated reflectivity of MAs on SD-OCT scans, graded as hypo-, moderate, or hyper-reflective, and their visualization at the level of SCP and deep ...

      Read Full Article
    5. USC Roski Eye Institute experts present novel research in preventive care, diagnosis and treatment of visual impairment and eye diseases at ARVO Annual Meeting

      USC Roski Eye Institute experts present novel research in preventive care, diagnosis and treatment of visual impairment and eye diseases at ARVO Annual Meeting

      The experts at the University of Southern California (USC) Roski Eye Institute , who for 42 years have pursued novel research that address blinding eye diseases, will present their latest groundbreaking studies at the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting held May 7-11 in Baltimore . "Research is at the heart of what we do at USC , it drives better preventive care, aids in improved diagnoses and creates innovative treatments that preserve, and in some cases, restore vision," said Rohit Varma , MD, MPH, dean of the Keck School of Medicine of USC and director of the USC Roski ...

      Read Full Article
    6. Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Purpose To describe a method to obtain images of the choroid using conventional spectral-domain (SD) optical coherence tomography (OCT) and to evaluate choroidal thickness measurements using these images. Design Observational case series. Methods The images were obtained by positioning the SD OCT device close enough to the eye to obtain an inverted representation of the fundus in healthy volunteers who did not have pupillary dilation. Seven sections, each comprised of 100 averaged scans, were obtained within a 5- × 15-degree rectangle centered on the fovea. The choroidal thickness under the fovea in each image was measured by independent observers. Results The ...

      Read Full Article
    7. Influence of eye biometrics and corneal micro-structure on noncontact tonometry

      Influence of eye biometrics and corneal micro-structure on noncontact tonometry

      Purpose Tonometry is widely used as the main screening tool supporting glaucoma diagnosis. Still, its accuracy could be improved if full knowledge about the variation of the corneal biomechanical properties was available. In this study, Optical Coherence Tomography (OCT) speckle statistics are used to infer the organisation of the corneal micro-structure and hence, to analyse its influence on intraocular pressure (IOP) measurements. Methods Fifty-six subjects were recruited for this prospective study. Macro and micro-structural corneal parameters as well as subject age were considered. Macro-structural analysis included the parameters that are associated with the ocular anatomy, such as central corneal thickness ...

      Read Full Article
    8. Influence of scanning area on choroidal vascularity index measurement using optical coherence tomography

      Influence of scanning area on choroidal vascularity index measurement using optical coherence tomography

      Purpose Recently, choroidal vascularity index (CVI) is proposed as a novel tool to evaluate the choroidal vasculature. In this study, we investigate the impact of scanning area on CVI measurement using spectral-domain optical coherence tomography (SD-OCT). Methods Spectral-domain optical coherence tomography (SD-OCT) using enhanced depth imaging mode was performed in 30 eyes from 15 normal subjects. Three scanning areas were compared: dingle foveal scan; central macular scans [scan passing through central 1000 microns circle on Early Treatment Diabetic Retinopathy Study (ETDRS) grid, inner circle]; and total macular cube scans. Binarization of OCT B-scans and segmentation of the binarized choroid layer ...

      Read Full Article
    9. ERG and OCT findings of a patient with a clinical diagnosis of occult macular dystrophy in a patient of Ashkenazi Jewish descent associated with a novel mutation in the gene encoding RP1L1

      ERG and OCT findings of a patient with a clinical diagnosis of occult macular dystrophy in a patient of Ashkenazi Jewish descent associated with a novel mutation in the gene encoding RP1L1

      A 57-year-old man with a past medical history of diabetes presented for consultation with a several year history of slowly progressive vision loss in both eyes, which continued to deteriorate over 7 years of follow-up. Multimodal imaging was performed and was significant for the following: on spectral domain optical coherence tomography, a gap lesion was present in the ellipsoid layer, beneath the umbo, as well as subtle macular changes on auto fluorescence imaging. Multifocal electroretinography was performed and was abnormal, and a clinical diagnosis of occult macular dystrophy was made. The patient was subsequently evaluated with genetic testing that revealed ...

      Read Full Article
    10. Evaluation of Femtosecond Laser Intrastromal Incision Location Using Optical Coherence Tomography

      Evaluation of Femtosecond Laser Intrastromal Incision Location Using Optical Coherence Tomography

      Purpose To use optical coherence tomography (OCT) to evaluate the femtosecond laser intrastromal incisions made during cataract surgery to reduce corneal astigmatism. Design Retrospective case series. Participants Seventy-seven eyes of 77 patients. Methods Paired intrastromal incisions were created using the Catalys femtosecond laser (Abbott Medical Optics, Inc., Santa Ana, CA). The planned intrastromal incision parameters were 20% uncut anterior, 20% uncut posterior, midpoint depth of 50%, and 90° side cut angle. Optical coherence tomography scans were obtained 3 weeks or more after surgery to assess these 4 parameters, and actual values were compared with intended values. Main Outcome Measures Percentages ...

      Read Full Article
    11. To Study the correlation between fundus fluorescein angiography and optical coherence tomography patterns in clinically significant macular oedema

      To Study the correlation between fundus fluorescein angiography and optical coherence tomography patterns in clinically significant macular oedema

      Background: To Study the correlation between Fundus Fluorescein Angiography and Optical Coherence Tomography patterns in Clinically Significant Macular Oedema. Methods: This is a retrospective study which compares patterns in FFA and OCT in patients with CSME. Results: A total of 54 eyes were examined. Participants included 64.81 % males and 34.85% females. On Fundus Fluorescein Angiography (FFA) 37.03% eyes showed diffuse leak, 27.77% eyes showed focal leak, 35.18 % eyes showed CME, 53.7% eyes showed macular ischemia. Maximum pattern is macular ischemia type in FFA. On OCT 42.6 % eyes showed spongy oedema, 68.51% eyes ...

      Read Full Article
    12. Choroidal Imaging with Swept-Source Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy: Choroidal Reflectivity and Thickness

      Choroidal Imaging with Swept-Source Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy: Choroidal Reflectivity and Thickness

      Purpose To characterize choroidal thickness and choroidal reflectivity in the eyes of patients with birdshot chorioretinopathy (BSCR). Design Cross-sectional observational study. Participants Two hundred twenty BSCR patients and 59 healthy controls. Methods Patients with BSCR and healthy controls underwent imaging of the macula in both eyes with a swept-source optical coherence tomography device (DRI-OCT1 Atlantis; Topcon). Images were exported from the device, and analysis was performed by 2 graders in the Doheny Image Reading Center using Image J software. The choroidal thickness at the foveal center was measured. In addition, the inner and outer boundaries of the choroid and retinal ...

      Read Full Article
      Mentions: UCLA
    13. Macular Ganglion Cell and Retinal Nerve Fiber Layer Thickness in Children With Refractive Errors-An Optical Coherence Tomography Study

      Macular Ganglion Cell and Retinal Nerve Fiber Layer Thickness in Children With Refractive Errors-An Optical Coherence Tomography Study

      Purpose: To study the distribution of macular ganglion cell-inner plexiform layer (GC-IPL) thickness and peripapillary retinal nerve fiber layer (RNFL) thickness in children with refractive errors. Materials and Methods: Two hundred forty-three healthy eyes from 139 children with refractive error ranging from -10.00 to +5.00 D were recruited from the National University Hospital Eye Surgery outpatient clinic. After a comprehensive ocular examination, refraction, and axial length (AL) measurement (IOLMaster), macular GC-IPL and RNFL thickness values were obtained with a spectral domain Cirrus high definition optical coherence tomography system (Carl Zeiss Meditec Inc.). Only scans with signal strength of ...

      Read Full Article
    14. Fundus autofluorescence in the buried optic disc drusen: optical coherence tomography findings

      Fundus autofluorescence in the buried optic disc drusen: optical coherence tomography findings

      Optic disc drusen (ODD) is hyaline material within the disc that frequently shows flecks of calcium. 1 Electron microscopic examination revealed that ODD is composed of aggregates of extracellular mitochondria containing calcium crystals. 2 Most diagnostic methods, such as B-scan ultrasonography and computed tomography, focus on the calcification signal. 3 However, calcification is not always detectable, as seen in the buried ODD. 4 Spectral-domain optical coherence tomography (SD-OCT) enables the acquisition of cross-sectional images of the optic nerve head with ODD. 5 , 6 , 7 Notably, SD-OCT can capture the margin of ODD without definite calcification. 5 , 6 ODD in childhood ...

      Read Full Article
    15. Spectral Domain-Optical Coherence Tomography As a New Diagnostic Marker for Idiopathic Normal Pressure Hydrocephalus | Neurology

      Spectral Domain-Optical Coherence Tomography As a New Diagnostic Marker for Idiopathic Normal Pressure Hydrocephalus | Neurology

      Purpose: Characterized by a progressive onset of gait disturbances, dementia, and urinary incontinence, idiopathic normal pressure hydrocephalus (iNPH) is considered a rare, but under-diagnosed disease. Non-invasive diagnostic markers are still insufficient to enable the diagnosis of iNPH with certainty and yet early treatment with ventriculoperitoneal (VP) shunting can reverse symptoms and stop disease progression. Vascular circulation abnormalities in iNPH may be reflected by changes in subfoveal and peripapillary choroidal thickness (PPChT). This study uses spectral domain-optical coherence tomography (SD-OCT)-based measures of retinal and choroidal thickness to test this hypothesis and to assess ophthalmological non-invasive markers for iNPH. Methods: Twelve ...

      Read Full Article
    16. Relationship Between OCT Angiography Temporal Peripapillary Vessel-Density and Octopus Perimeter Paracentral Cluster Mean Defect

      Relationship Between OCT Angiography Temporal Peripapillary Vessel-Density and Octopus Perimeter Paracentral Cluster Mean Defect

      Purpose of the Study: The purpose of the study was to investigate the relationship between optical coherence tomography angiography angioflow vessel-density (PAFD) measured in the retinal nerve fiber layer in the temporal peripapillary sector and the average of the spatially corresponding superior and inferior paracentral cluster mean defect values (mean paracentral MD) measured with Octopus perimetry. Materials and Methods: Spaerman’s correlation between temporal peripapillary PAFD acquired with the Angiovue OCT and mean paracentral MD measured with the Normal and tendency-oriented perimetry strategy of Octopus G2 perimetry, respectively, was determined on 1 eye of 13 healthy participants, 22 medically controlled ...

      Read Full Article
    17. Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy

      Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy

      Purpose: To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. Materials and Methods: A novel AS-OCT grading system based on bleb size and internal reflectivity was developed. An imaging center was tasked with masked grading of AS-OCT images acquired by multiple surgical sites at postoperative week (POW) 2, postoperative month (POM) 4, 6, and 12, respectively. The Moorfields Bleb Grading System was used by another independent imaging center to grade clinical photos. The results of the 2 grading systems were compared ...

      Read Full Article
    18. Optical Coherence Tomography and Glaucoma Progression: A Comparison of a Region of Interest Approach to Average Retinal Nerve Fiber Layer Thickness

      Optical Coherence Tomography and Glaucoma Progression: A Comparison of a Region of Interest Approach to Average Retinal Nerve Fiber Layer Thickness

      Purpose: To determine whether the change in the retinal nerve fiber layer (RNFL) thickness in a region of interest (ROI) is a better measure of glaucoma progression than the change in average circumpapillary (cp) RNFL thickness. Methods: Disc cube scans were obtained with frequency domain optical coherence tomography from 60 eyes of 60 patients (age, 61.7±12.7 y) with early or suspected glaucoma and controlled intraocular pressure. The average time between 2 test dates was 3.2±1.8 years. En-face images of the scans from the 2 tests were aligned based on the blood vessels, and cp ...

      Read Full Article
    19. Determinants of Peripapillary and Macular Vessel Densities Measured by Optical Coherence Tomography Angiography in Normal Eyes

      Determinants of Peripapillary and Macular Vessel Densities Measured by Optical Coherence Tomography Angiography in Normal Eyes

      PURPOSE The aim of this study was to evaluate the effect of subject-related (age, sex, and systemic hypertension and diabetes), eye-related (refractive error, optic disc size), and technology-related (signal strength index, SSI of the scans) determinants on the peripapillary and macular vessel densities measured with optical coherence tomography angiography (OCTA) in normal eyes. METHODS In a cross-sectional study, 181 normal eyes of 107 subjects (45 men, 62 women, median age: 50 y, range: 18 to 77 y) underwent OCTA imaging. Linear mixed models were used to analyze the effect of the determinants on the peripapillary and macular vessel densities measured ...

      Read Full Article
    20. The Association Between Clinical Features Seen on Fundus Photographs and Glaucomatous Damage Detected on Visual Fields and Optical Coherence Tomography Scans

      The Association Between Clinical Features Seen on Fundus Photographs and Glaucomatous Damage Detected on Visual Fields and Optical Coherence Tomography Scans

      Purpose: To classify the appearance of the optic disc seen on fundus photographs of healthy subjects and patients with or suspected glaucoma whose diagnosis was based upon visual fields (VFs) and spectral-domain optical coherence tomography (sdOCT) results. Patients and Methods: One eye of 100 patients with or suspected glaucoma and 62 healthy subjects were prospectively tested with 24-2 and 10-2 VF and macular and disc sdOCT cube scans. All eyes with or suspected glaucoma had a 24-2 mean deviation better than −6.0 dB and an abnormal appearing disc on stereophotographs. The retinal ganglion cell plus inner plexiform layer (RGC ...

      Read Full Article
    21. Supervised learning and dimension reduction techniques for quantification of retinal fluid in optical coherence tomography images

      Supervised learning and dimension reduction techniques for quantification of retinal fluid in optical coherence tomography images

      Purpose The purpose of the present study is to develop fast automated quantification of retinal fluid in optical coherence tomography (OCT) image sets. Methods We developed an image analysis pipeline tailored towards OCT images that consists of five steps for binary retinal fluid segmentation. The method is based on feature extraction, pre-segmention, dimension reduction procedures, and supervised learning tools. Results Fluid identification using our pipeline was tested on two separate patient groups: one associated to neovascular age-related macular degeneration, the other showing diabetic macular edema. For training and evaluation purposes, retinal fluid was annotated manually in each cross-section by human ...

      Read Full Article
    553-576 of 9669 « 1 2 ... 21 22 23 24 25 26 27 ... 401 402 403 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (7 articles) National Institutes of Health
    2. (4 articles) Singapore Eye Research Institute
    3. (3 articles) Center for Ophthalmic Optics and Lasers
    4. (3 articles) Oregon Health & Science University
    5. (3 articles) Centre Hospitalier Intercommunal de Créteil
    6. (3 articles) University of Washington
    7. (3 articles) University of Ulsan
    8. (3 articles) University of Southern California
    9. (3 articles) Shanghai Jiao Tong University
    10. (3 articles) Università Vita-Salute San Raffaele
    11. (2 articles) UCSD
    12. (2 articles) University of Iowa
  4. People in the News

    1. (4 articles) Francesco Bandello
    2. (4 articles) Giuseppe Querques
    3. (3 articles) David Huang
    4. (2 articles) Robert Ritch
    5. (2 articles) Donald C. Hood
    6. (2 articles) Sina Farsiu
    7. (2 articles) Michael S. Kook
    8. (2 articles) Robert N. Weinreb
    9. (2 articles) Jeffrey M. Liebmann
    10. (2 articles) Jaewan Choi
    11. (1 articles) Hideki Koizumi
    12. (1 articles) Ou Tan
  5. OCT Companies in the News

    1. (9 articles) Optovue
    2. (5 articles) Carl Zeiss Meditec
    3. (3 articles) Heidelberg Engineering
    4. (2 articles) Topcon Medical Systems
    5. (2 articles) Tomey Corporation
    6. (2 articles) Nidek
    7. (1 articles) Leica
    8. (1 articles) Bausch & Lomb
    9. (1 articles) Lumedica
    10. (1 articles) Opticent Health
    11. (1 articles) Notal Vision
    12. (1 articles) Bioptigen