1. Articles in category: Ophthalmology

    553-576 of 6234 « 1 2 ... 21 22 23 24 25 26 27 ... 258 259 260 »
    1. Intraocular lenses and Japan tax hike drive Meditec growth

      Intraocular lenses and Japan tax hike drive Meditec growth

      In his letter to shareholders, Monz also highlighted the recent introduction of the first ophthalmic surgery microscope to feature an integrated optical coherence tomography (OCT) camera as evidence of the company’s ongoing innovation. “The unique combination of two established Zeiss gold standards means we can now offer surgeons more comprehensive visualization during surgery, which enables better treatment results,” Monz wrote. Fierce competition in diagnostics Though growing fast, the surgical ophthalmology business unit remains Meditec’s smallest, accounting for €73.4 million of sales in the six months to the end of March. Multifocal and premium toric lenses developed recently ...

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    2. Feature Of The Week 4/11/14: Virtual Reality Simulator for Vitreoretinal Surgery using Integrated OCT Data

      Feature Of The Week 4/11/14: Virtual Reality Simulator for Vitreoretinal Surgery using Integrated OCT Data

      Its clear that OCT is playing increasingly important role in integrated surgical devices. There are numerous research and clinical papers that have been recently published and there are several innovative companies that have products in this area including Zeiss, Bioptigen, LenSx, Optimedica, and others. Its natural that virtual reality simulators would play a role in training surgeons to uses these tools. Recently researchers from King Khaled Eye Specialist Hospital and University of Illinois College of Engineering published preliminary results on this topic as shown below. Operative practice using surgical simulators has become a part of training in many surgical specialties ...

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    3. The Safer Method of Sub-Tenon’s Bevacizumab Injection with Central Serous Chorioretinopathy: A Noninvasive Evaluation by Series of Optic Coherence Tomography

      The Safer Method of Sub-Tenon’s Bevacizumab Injection with Central Serous Chorioretinopathy: A Noninvasive Evaluation by Series of Optic Coherence Tomography

      To evaluate the outcome of patients with central serous chorioretinopathy (CSCR) after deep sub-tenon bevacizumab injection by the noninvasive evaluation by optic coherence tomography (OCT). Methods: Three patients having CSCR with moderate to severe vision loss were treated with at least two time of sub-tenon bevacizumab injection (0.3 ml). All the patients underwent the complete examinations at the baseline and follow-up visits. This ocular evaluation included the bare and best-corrected visual acuity (by Snellen chart), fundus biomicroscopy and OCT in each visit. Results: The follow-up point ranged between 2 and 6 months. Improvement of vision was observed, and they ...

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    4. Optical coherence tomographic assessment of retinal nerve fiber layer thickness changes before and after glaucoma filtration surgery

      Optical coherence tomographic assessment of retinal nerve fiber layer thickness changes before and after glaucoma filtration surgery

      Background: Glaucomatous Optic Neuropathy (GON) is very common in the glaucoma patients, and impaired effect of glaucoma is measured by the Retinal Nerve Fiber Layer (RNFL) thickness. Objective: The study was conducted to find out the mean RNFL thickness, RNFL thickness in different quadrants, Intra-Ocular Pressure (IOP) changes, and visual field changes after filtration surgery in different ages and genders using Optical Coherence Tomography (OCT). Materials and Methods: The study was an interventional case-series conducted at the Glaucoma Clinic at the Regional Institute of Ophthalmology at Kolkata from March 2009 to August 2010. Fifty-one eyes of 43 open angle glaucoma ...

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    5. Evaluation of Optic Nerve Development in Preterm and Term Infants Using Handheld Spectral-Domain Optical Coherence Tomography

      Evaluation of Optic Nerve Development in Preterm and Term Infants Using Handheld Spectral-Domain Optical Coherence Tomography

      Purpose To evaluate effects of prematurity on early optic nerve (ON) development and the usefulness of ON parameters as indicators of central nervous system (CNS) development and pathology. Design Prospective, cross-sectional, longitudinal study. Participants Forty-four preterm infants undergoing retinopathy of prematurity (ROP) screening and 52 term infants. Methods We analyzed ON from portable handheld spectral-domain optical coherence tomography (SD-OCT) images (Bioptigen, Inc, Research Triangle Park, NC) of 44 preterm and 52 term infants. The highest-quality ON scan from either eye was selected for quantitative analysis. Longitudinal analysis was performed at 31–36 weeks and 37–42 weeks postmenstrual age (PMA ...

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    6. Alcon, Carl Zeiss and Bausch & Lomb Lead the European Ophthalmic Device Market to Over €700 million by 2020

      Alcon, Carl Zeiss and Bausch & Lomb Lead the European Ophthalmic Device Market to Over €700 million by 2020

      According to a new report by iData Research ( http://www.idataresearch.com ), the leading global authority in medical device and pharmaceutical market research, the European diagnostic and interventional ophthalmic device market is expected to exceed €700 million by 2020. There are two main drivers fueling this market, technological innovation and the increasingly aging population that are affected with ocular diseases. As the population ages, the prevalence of ocular diseases such as cataracts and glaucoma increases. In addition, refractive problems such as myopia, hyperopia and astigmatism are more likely to occur in older people. These factors drive demand for specialized ophthalmic ...

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    7. Washington University Receives NIH Grant for Studying Mechanics of Early Brain and Eye Development

      Washington University Receives NIH Grant for Studying Mechanics of Early Brain and Eye Development

      Washington University Receives a 2014 NIH Grant for $332,591 for Studying Mechanics of Early Brain and Eye Development. The principle investigator is Larry Taber. The program beganin 2010 and ends in 2015. Below is a summary of the proposed work. In human embryos, the primary subdivisions of the brain (forebrain, midbrain, and hindbrain) are formed by the fourth week of gestation. During this time, the primitive eyes (optic vesicles) emerge as protrusions from the forebrain. The forms of these organs are highly conserved. Abnormalities in size and shape of the early brain are known to cause serious neurological disorders ...

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    8. University of Iowa Receiveds NIH Grant for Retinal Therapy Guided by 2-D OCT Imaging Analysis

      University of Iowa Receiveds NIH Grant for Retinal Therapy Guided by 2-D OCT Imaging Analysis

      University of Iowa Received a 2014 NIH Grant for $516,408 for Retinal Therapy Guided by 2-D OCT Imaging Analysis. The principle investigator is Milan Sonka. The program began in 2010 and ends in 2015. Below is a summary of the proposed work. Age related macular degeneration (AMD) is one of the primary causes of blindness in the U.S. A wealth of powerful new treatments, especially anti-VEGF agents, have recently become available to restore visual function in choroidal neovascularization (CNV), the most severe form of AMD. The risk of ocular adverse events increases with repeated intravitreal treatment injections. Ideally ...

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    9. University of Iowa Receives NIH Grant for 3D image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema.

      University of Iowa Receives NIH Grant for 3D image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema.

      University of Iowa Receives a 2014 NIH Grant for $332,955 for 3D image Analysis Approach to Determine Severity and Cause of Optical Nerve Edema. The principal investigator is Mona Garvin. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Currently, the clinical assessment of optic nerve swelling is limited by the subjective ophthalmoscopic evaluation by experts in order to diagnose and differentiate the cause of the optic disc edema. The long-term goal of our research effort is to develop automated 3D image-analysis approaches for the identification of an optimal set of ...

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    10. Agreement of Two Different Spectral Domain Optical Coherence Tomography Instruments for Retinal Nerve Fiber Layer Measurements

      Agreement of Two Different Spectral Domain  Optical Coherence Tomography Instruments for  Retinal Nerve Fiber Layer Measurements

      Purpose: To determine the agreement between Spectralis and Cirrus spectral domain optical coherence tomography (SD-OCT) measurements of peripapillary retinal nerve fiber layer (RNFL) thickness. Methods: Suspected or confirmed cases of glaucoma who met the inclusion criteria underwent peripapillary RNFL thickness measurement using both the Spectralis and Cirrus on the same day within a few minutes. Results: Measurements were performed on 103 eyes of 103 patients with mean age of 50.4±17.7 years. Mean RNFL thickness was 89.22±15.87 versus 84.54±13.68 µm using Spectralis and Cirrus, respectively. The difference between measurements and the average ...

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    11. Spectral-domain optical coherence tomography epithelial and flap thickness mapping in femtosecond laser-assisted in situ keratomileusis

      Spectral-domain optical coherence tomography epithelial and flap thickness mapping in femtosecond laser-assisted in situ keratomileusis

      Purpose To evaluate the change of epithelial and flap thickness after femtosecond laser-assisted in situ keratomileusis (LASIK) using Spectral-domain optical coherence tomography (SD-OCT) in correlation with the spherical equivalent refraction treated and clinical outcomes. Design Prospective, randomized, contralateral eye study. Methods 40 myopic eyes underwent LASIK using the ALLEGRETTO ® Eye-Q excimer laser with refraction ranging from -1.00 to -7.25 diopters (mean -3.25±1.9). Flap creation was randomized between eyes, using the IntraLASE FS60 (IL) in one eye and WaveLight FS200 (FS) in the contralateral eye. SD-OCT (Optovue RTVue-100) was used to evaluate the epithelial and flap ...

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    12. Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients

      Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients

      Background To describe the clinical and optical coherence tomography (OCT) features of focal choroidal excavation in Chinese patients. Methods Retrospectively, thirty-seven eyes (in 31 patients) that demonstrated focal choroidal excavation on spectral-domain OCT were collected. Their clinical characteristics and other features were also collected and analyzed. Results In total, 42 focal choroidal excavations were identified in 31 patients, including 25 unilateral and 6 bilateral (37 eyes). The abnormal changes in these eyes with choroidal excavation were more prominent at the outer part of the neuro-retina, the retinal pigment epithelium (RPE) and the choroid. The average transverse diameter and depth of ...

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    13. Short coherence interferometer

      Short coherence interferometer

      A short coherence interferometer apparatus for measuring multiple axially spaced regions of a specimen, in particular the eye, which has at least one measuring beam path, through which multiple individual measuring beams are incident on the specimen, and one reference beam path, through which a reference beam runs, with which the individual measuring beams are superimposed and brought into interference. The individual measuring beams are axially offset to one another upon incidence on the specimen by an amount which is adapted to the axial spacing. The interferometer apparatus superimposes each individual measuring beam with the reference beam in an interfering ...

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    14. Apparatus and method for imaging an eye

      Apparatus and method for imaging an eye

      The present invention is a slit lamp mounted eye imaging, a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus and method for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical ...

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    15. A Simplified Method to Measure Choroidal Thickness Using Adaptive Compensation in Enhanced Depth Imaging Optical Coherence Tomography

      A Simplified Method to Measure Choroidal Thickness Using Adaptive Compensation in Enhanced Depth Imaging Optical Coherence Tomography

      Purpose To evaluate a simplified method to measure choroidal thickness (CT) using commercially available enhanced depth imaging (EDI) spectral domain optical coherence tomography (SD-OCT). Methods We measured CT in 31 subjects without ocular diseases using Spectralis EDI SD-OCT. The choroid-scleral interface of the acquired images was first enhanced using a post-processing compensation algorithm. The enhanced images were then analysed using Photoshop. Two graders independently graded the images to assess inter-grader reliability. One grader re-graded the images after 2 weeks to determine intra-grader reliability. Statistical analysis was performed using intra-class correlation coefficient (ICC) and Bland-Altman plot analyses. Results Using adaptive compensation ...

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    16. Johns Hopkins University Receives NIH Grant for Imaging Neurodegeneration in Multiple Sclerosis

      Johns Hopkins University Receives  NIH Grant for Imaging Neurodegeneration in Multiple Sclerosis

      Johns Hopkins University Receives a 2014 NIH Grant for $436,412 for Imaging Neurodegeneration in Multiple Sclerosis. The principle investigator is Peter Calabresi. The program begain in 2013 and ends in 2018. Below is a summary of the proposed work. There is emerging evidence that gray matter (GM) degeneration is common in multiple sclerosis (MS), and more closely linked with disability than white matter (WM) injury. Indeed, WM volumes, as measured by high resolution MRI, wax and wane as a reflection of inflammation, whereas GM atrophy accelerates with time in MS. Whether GM degeneration purely results from WM injury or ...

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    17. Bioptigen Receives NIH Grant for Pediatric Spectral Domain Optical Coherence Tomography

      Bioptigen Receives NIH Grant for Pediatric Spectral Domain Optical Coherence Tomography

      Bioptigen Receives 2014 NIH grant for $99,516 for Pediatric Spectral Domain Optical Coherence Tomography. The principle investigator is Eric Buckland. The program began in 2008 and ends in 2015. Below is a summary of the proposed work. Acquiring diagnostic images of the retina in children is necessary to the prevention and treatment of pediatric eye disease, but it is often difficult due to the large range of eye shapes and sizes from preemies to older children and the inability of most children within this range to fixate. Fundus photography only provides a two- dimensional surface picture of the retina ...

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    18. Modern technologies for retinal scanning and imaging: an introduction for the biomedical engineer

      Modern technologies for retinal scanning and imaging: an introduction for the biomedical engineer

      This review article is meant to help biomedical engineers and nonphysical scientists better understand the principles of, and the main trends in modern scanning and imaging modalities used in ophthalmology. It is intended to ease the communication between physicists, medical doctors and engineers, and hopefully encourage "classical" biomedical engineers to generate new ideas and to initiate projects in an area which has traditionally been dominated by optical physics. Most of the methods involved are applicable to other areas of biomedical optics and optoelectronics, such as microscopic imaging, spectroscopy, spectral imaging, opto-acoustic tomography, fluorescence imaging etc., all of which are with ...

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    19. Sequential Spectral Domain Optical Coherence Tomography Imaging of An Eye After Successful Removal of Subfoveal Perfluorcarbon Liquid Collection

      Sequential Spectral Domain Optical Coherence Tomography Imaging of An Eye After Successful Removal of Subfoveal Perfluorcarbon Liquid Collection

      Purpose: To evaluate retinal restoration after subfoveal perfluorcarbon liquid (PFCL) bubble removal by means of autofluorescence, infrared, and spectral domain optical coherence tomography over 2 years of follow-up. Methods: A 62-year-old patient underwent two 23-gauge vitrectomies in attempt to remove subretinal PFCL retained under the fovea secondary to retinal detachment surgery in the left eye. We assessed best-corrected visual acuity, fundus biomicroscopy, retinal imaging by autofluorescence, infrared, and spectral domain optical coherence tomography at the first observation of retained PFCL, 1 day after the first attempt of PFCL removal, and 1, 30, 90, and 180 days, and 2 years after ...

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    20. Influence of Correction of Ocular Magnification on Spectral-Domain OCT Retinal Nerve Fiber Layer Measurement Variability and Performance

      Influence of Correction of Ocular Magnification on Spectral-Domain OCT Retinal Nerve Fiber Layer Measurement Variability and Performance

      Purpose: To analyze the influence of ocular magnification on the peripapillary retinal nerve fiber layer (RNFL) thickness measurement and its performance as acquired with spectral-domain optical coherence tomography (SD-OCT). Methods: SD-OCT measurements from 108 normal eyes (59 subjects) and 72 glaucoma eyes (58 patients) were exported and custom software was used to correct RNFL measurements for ocular magnification. RNFL prediction limits in normal subjects, structure-function relationships, and RNFL performance for detection of glaucoma were compared before and after correction for ocular magnification (Bennett's formula). Association of disc area with cross-sectional RNFL area was explored. Results: The median (interquartile range ...

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    21. Sectoral variations of iridocorneal angle width and iris volume in Chinese Singaporeans: a swept-source optical coherence tomography study

      Sectoral variations of iridocorneal angle width and iris volume in Chinese Singaporeans: a swept-source optical coherence tomography study

      Purpose To assess variations in the iridocorneal angle width and iris volume in Chinese subjects using swept-source optical coherence tomography (SS-OCT). Methods Consecutive subjects, aged 40–80 years, with no previous ophthalmic problems were recruited from a population-based study of Chinese Singaporeans. All subjects underwent 360° SS-OCT (SS-1000 CASIA, Tomey Corporation, Nagoya, Japan) angle imaging and gonioscopy in one randomly selected eye in the dark. For each eye, 16 frames (11.25° apart) were selected for analysis from 128 cross-sectional images, and measurements of the trabecular iris space area 750 μm from the scleral spur (TISA750) and iris volume were ...

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    22. Improvement of visual acuity based on optical coherence tomography patterns following intravitreal bevacizumab treatment in patients with diabetic macular edema

      Improvement of visual acuity based on optical coherence tomography patterns following intravitreal bevacizumab treatment in patients with diabetic macular edema

      AIM: To report the visual outcome based on various patterns of optical coherence tomography (OCT) morphology in diabetic macular edema (DME), following treatment with anti-VEGF intravitreal bevacizumab (IVB) injection. METHODS: Sixty-seven consecutive subjects with centre involving DME underwent intravitreal injection of Bevacizumab (1.25 mg/0.05 mL) in this retrospective, comparative, non randomized study. The DME was classified into one of four categories:focal, diffuse, focal cystoid and neurosensory detachment based on OCT. Best corrected visual acuity (BCVA), macular appearance, and OCT findings were used to decide whether the subject should have a repeat injection of intravitreal bevacizumab. Outcome ...

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    23. Comparison of autofluorescence and optical coherence tomography findings in acute and chronic central serous chorioretinopathy

      Comparison of autofluorescence and optical coherence tomography findings in acute and chronic central serous chorioretinopathy

      AIM: To discuss and compare the fundus autofluorescence (FAF) and optical coherence tomography (OCT) in acute or chronic central serous chorioretinopathy (CSCR). METHODS: Medical records of 100 cases of CSCR were reviewed. Acute and chronic cases were evaluated according to the duration of decreased visual acuity, serous retinal detachment (RD) and focal leakage on fluorescein angiography (FA). Chi-square test was used for statistical analysis. RESULTS: Forty cases had acute and 60 cases had chronic CSCR. FAF showed focal hypo-autofluorescence in 34 (85%) and iso-autofluorescence in 6 (15%) of acute cases and hypo-autofluorescence in 51 (85%), hyper-autofluorescence in 6 (10%) and ...

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