1. Articles in category: Ophthalmology

    1-24 of 13176 1 2 3 4 ... 547 548 549 »
    1. Circumpapillary collateral vessel development in iatrogenic central retinal artery occlusion observed using OCT angiography

      Circumpapillary collateral vessel development in iatrogenic central retinal artery occlusion observed using OCT angiography

      Purpose It has been reported that peripapillary loops develop after central retinal artery occlusion (CRAO). Although cilioretinal anastomoses have been shown by fluorescein angiography (FA) and indocyanine green angiography, these examinations cannot confirm the structural continuity between the retinal arteries and the posterior ciliary arteries. In the current report, we followed a patient with iatrogenic CRAO in which circumpapillary collaterals formed and assessed the connection between these two vascular systems using optical coherence tomography angiography (OCTA). Observation Iatrogenic CRAO developed in the left eye of a 30-year-old woman during preoperative embolization of a convexity meningioma. FA and OCTA showed complete ...

      Read Full Article
    2. Assessment of retinal vascular network in amnestic mild cognitive impairment by optical coherence tomography angiography

      Assessment of retinal vascular network in amnestic mild cognitive impairment by optical coherence tomography angiography

      Objective To assess the presence of retinal vascular network abnormalities in amnestic mild cognitive impairment (aMCI) patients and healthy subjects (HS) through optical coherence tomography angiography (OCTA). Methods OCTA and SD-OCT were performed in aMCI patients and cognitive normal HS. A complete neuropsychological evaluation was performed. Differences in vessel density (VD) in each retinal vascular plexus and in foveal avascular zone (FAZ) were evaluated with linear mixed model after correction for age, sex and disease duration. Results Twenty-seven aMCI patients (10 Single domain aMCI, 17 Multidomain aMCI) and 29 HS were enrolled. aMCI patients showed a statistically significant reduced VD ...

      Read Full Article
      Mentions: Optovue
    3. Nanosensitive optical coherence tomography to assess wound healing within the cornea

      Nanosensitive optical coherence tomography to assess wound healing within the cornea

      Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high resolution imaging, the best ultra-high-resolution OCT systems are limited to imaging structural changes with a resolution of one micron on a single B-scan within very limited depth. Nanosensitive OCT (nsOCT) is a recently developed technique that is capable of providing enhanced sensitivity of OCT to structural changes. Improving the sensitivity of OCT to detect structural changes at the nanoscale level, to a depth typical for conventional OCT, could potentially ...

      Read Full Article
    4. Point-wise correlations between 10-2 Humphrey visual field and OCT data in open angle glaucoma

      Point-wise correlations between 10-2 Humphrey visual field and OCT data in open angle glaucoma

      Purpose Optical Coherence Tomography (OCT) is a powerful instrument for helping clinicians detect and monitor glaucoma. The aim of this study was to provide a detailed mapping of the relationships between visual field (VF) sensitivities and measures of retinal structure provided by a commercial Spectral Domain (SD)-OCT system (RTvue-100 Optovue). Methods Sixty-three eyes of open angle glaucoma patients (17 males, 16 females, and mean age 71 ± 7.5 years) were included in this retrospective, observational clinical study. Thickness values for superior and inferior retina, as well as average values, were recorded for the full retina, the outer retina, the ...

      Read Full Article
    5. Optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy due to optic nerve head drusen

      Optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy due to optic nerve head drusen

      Optic nerve head drusen (ONHD) are typically benign hyaline and calcified concretions located within the optic nerve. Initially asymptomatic, they can increase slowly in size and number over time, and they can cause mechanical stress at the axons of the optic nerve and progressively lead to a loss of the visual field and papillary vascular changes. Here, we reported a rare case of a young patient with bilateral ONHD complicated by a nonarteritic anterior ischemic optic neuropathy (NAION) in the right eye. The aim of this case was to evaluate, using optical coherence tomography angiography (OCTA), the vascular network of ...

      Read Full Article
    6. Structural assessment of the optic nerve in patients with obstructive sleep apnea syndrome: Case–control study

      Structural assessment of the optic nerve in patients with obstructive sleep apnea syndrome: Case–control study

      Objective Obstructive sleep apnea syndrome has been identified as a possible risk factor for optic nerve pathology such as glaucoma, nonarteritic ischemic optic neuropathy, and optic disk edema. Accordingly, we aimed to evaluate structural changes of the apparently normal optic nerve in obstructive sleep apnea syndrome patients with effects of its severity. Materials and methods In this prospective case–control study, 47 eyes of 47 obstructive sleep apnea syndrome patients diagnosed with polysomnography and 40 eyes of 40 healthy subjects were included. Spectral-domain optical coherence tomography was used to evaluate the peripapillary retinal nerve fiber layer thickness, optic nerve head ...

      Read Full Article
    7. University of Washington Receives NIH Grant for Optical Coherence Elastography of Corneal Dynamics

      University of Washington Receives NIH Grant for Optical Coherence Elastography of Corneal Dynamics

      University of Washington Receives a 2020 NIH Grant for $560,406 for Optical Coherence Elastography of Corneal Dynamics. The principal investigator is Tueng Shen. Below is a summary of the proposed work. The cornea is a highly organized, layered (lamellae) structure of collagen fibrils providing both high tensile strength to protect the eye and 70% of it refractive power. Although physical properties are closely linked to its primary optical function, its response to surgical interventions, and the results of routine eye tests such as intraocular pressure measurements, corneal biomechanics has not been a topic of major research interest. Topography, tonometry ...

      Read Full Article
    8. Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Translation

      Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Translation

      Duke University Receives a 2020 NIH Grant for $188,771for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Translation. The principal investigator is Joseph Izatt. Below is a summary of the proposed work. This is an application for an Exploratory/Developmental Research Grant which brings together a team of experts in ophthalmic imaging, surgery and robotics to advance the state of the art in image-guided robotic microsurgical intervention. Corneal transplants are one of the most commonly performed allograft procedures worldwide, although there remains a substantial risk of immune rejection or graft failure. An alternative form of corneal transplantation ...

      Read Full Article
    9. Optical Coherence Tomography Angiography in Glaucoma Care

      Optical Coherence Tomography Angiography in Glaucoma Care

      Purpose: To provide the reader with information on the principal techniques of optical coherence tomography angiography (OCTA); the current literature on OCTA reproducibility; its applications to glaucoma detection and monitoring of progression; and the role of OCTA in the assessment of the vascular component in glaucoma pathogenesis. Methods: A literature review of the pertinent publications for the OCTA in relation to the development, techniques, and its use in glaucoma was carried out. Results: Rapid improvements in optical coherence tomography (OCT) technology have allowed for enhancement of both image resolution and scanning speed, and the development of vascular assessment modality. OCTA ...

      Read Full Article
    10. What Is the Impact of Intraoperative Microscope-Integrated OCT in Ophthalmic Surgery? Relevant Applications and Outcomes. A Systematic Review

      What Is the Impact of Intraoperative Microscope-Integrated OCT in Ophthalmic Surgery? Relevant Applications and Outcomes. A Systematic Review

      Background: Optical coherence tomography (OCT) has recently been introduced in the operating theatre. The aim of this review is to present the actual role of microscope-integrated optical coherence tomography (MI-OCT) in ophthalmology. Method: A total of 314 studies were identified, following a literature search adhering to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. After full-text evaluation, 81 studies discussing MI-OCT applications in ophthalmology were included. Results: At present, three microscope-integrated optical coherence tomography systems are commercially available. MI-OCT can help anterior and posterior segment surgeons in the decision-making process, providing direct visualization of anatomic planes before ...

      Read Full Article
    11. Optical Coherence Tomography Angiography in Neurodegenerative Disorders

      Optical Coherence Tomography Angiography in Neurodegenerative Disorders

      Retinal microcirculation shares similar features with cerebral small blood vessels. Thus, the retina may be considered an accessible ‘window’ to detect the microvascular damage occurring in the setting of neurodegenerative disorders. Optical coherence tomography angiography (OCT-A) is a non-invasive imaging modality providing depth resolved images of blood flow in the retina, choroid, and optic nerve. In this review, we summarize the current literature on the application of OCT-A in glaucoma and central nervous system conditions such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Future directions aiming at evaluating whether OCT-A can be an additional biomarker for the ...

      Read Full Article
    12. LighTopTech Corp. Receives Small Business Innovation Research Phase II Award from the US National Institutes of Health (NIH)

      LighTopTech Corp. Receives Small Business Innovation Research Phase II Award from the US National Institutes of Health (NIH)

      LighTopTech Corp., an upstate New York-based company building innovative optical instruments to bring to market disruptive imaging technologies industrial and medical fields, has been awarded a Phase II Small Business Innovation Research (SBIR) award by the National Eye Institute of the National Institutes of Health (NIH). The NIH Phase II award will allow LighTopTech to develop the first 3D high-definition imaging instrument based on Gabor-Domain Optical Coherence Microscopy (GDOCM) for quantitative assessment of corneal tissue at eye banks. LighTopTech will develop and apply machine learning methods to automatically segment the endothelial cells of the cornea and count them to assess ...

      Read Full Article
    13. Cross‐scanning optical coherence tomography angiography for eye motion correction

      Cross‐scanning optical coherence tomography angiography for eye motion correction

      We propose a cross‐scanning optical coherence tomography (CS‐OCT) system to correct eye motion artifacts in OCT angiography images. This system employs a dual illumination configuration with two orthogonally polarized beams, each of which simultaneously perform raster scanning in perpendicular direction with each other over the same area. In the reference arm, a polarization delay unit is used to acquire the two orthogonally polarized interferograms with a single photodetector by introducing different optical delay lines. The two cross‐scanned volume data are affected by the same eye motion but in two orthogonal directions. We developed a motion correction algorithm ...

      Read Full Article
      Mentions: Korea University
    14. Reversible retinoschisis following high voltage electrical injury evaluated with optical coherence tomography and electrophysiology

      Reversible retinoschisis following high voltage electrical injury evaluated with optical coherence tomography and electrophysiology

      Purpose To report a carefully studied case of high voltage electrical injury of the retina and optic nerve with anatomically reversible retinoschisis. Methods Observational case report. Results A 22 year old power company worker was electrocuted with 12,000 V, with his left forehead being the exit point of the current. After regaining consciousness he reported decreased vision with both eyes. He was extensively tested with optical coherence tomography (OCT) and angiography (OCT-A), fundus photography, fluorescein angiography (FA), multifocal electroretinography (mfERG), full field electroretinography (ffERG), visual evoked potentials (VEP), and Goldmann-type Octopus automated perimetry in addition to careful clinical examinations ...

      Read Full Article
    15. Fundus fluorescein angiography and optical coherence tomography findings in ocular and non-ocular Behҫet’s disease

      Fundus fluorescein angiography and optical coherence tomography findings in ocular and non-ocular Behҫet’s disease

      Aim of the work This study aimed at early detection of fundus fluorescein angiography (FFA) findings and optical coherence tomography (OCT) changes denoting active posterior uveitis in Behçet’s Disease (BD) patients before they are clinically evident. Patients and methods This study included 50 BD patients subgrouped according to ocular involvement into ocular and non-ocular Behçet patients. All patients underwent thorough ophthalmological examination. Fundus examination was done to detect signs of intermediate and/or posterior uveitis. OCT conventional and enhanced depth techniques were used for assessment of the macular area and choroidal thickness respectively. FFA was done for ...

      Read Full Article
    16. Deep learning architectures analysis for age-related macular degeneration segmentation on optical coherence tomography scans

      Deep learning architectures analysis for age-related macular degeneration segmentation on optical coherence tomography scans

      Background and Objectives: Aged people usually are more to be diagnosed with retinal diseases in developed countries. Retinal capillaries leakage into the retina swells and causes an acute vision loss, which is called age-related macular degeneration (AMD). The disease can not be adequately diagnosed solely using fundus images as depth information is not available. The variations in retina volume assist in monitoring ophthalmological abnormalities. Therefore, high-fidelity AMD segmentation in optical coherence tomography (OCT) imaging modality has raised the attention of researchers as well as those of the medical doctors. Many methods across the years encompassing machine learning approaches and convolutional ...

      Read Full Article
    17. The eye, the kidney, and cardiovascular disease: old concepts, better tools, and new horizons

      The eye, the kidney, and cardiovascular disease: old concepts, better tools, and new horizons

      Chronic kidney disease (CKD) is common, with hypertension and diabetes mellitus acting as major risk factors for its development. Cardiovascular disease is the leading cause of death worldwide and the most frequent end point of CKD. There is an urgent need for more precise methods to identify patients at risk of CKD and cardiovascular disease. Alterations in microvascular structure and function contribute to the development of hypertension, diabetes, CKD, and their associated cardiovascular disease. Homology between the eye and the kidney suggests that noninvasive imaging of the retinal vessels can detect these microvascular alterations to improve targeting of at-risk patients ...

      Read Full Article
    18. Optical Coherence Tomography Findings in Tamoxifen Retinopathy

      Optical Coherence Tomography Findings in Tamoxifen Retinopathy

      Purpose To describe optical coherence tomography (OCT) findings in two cases of typical tamoxifen retinopathy. Design Observational cases report. Methods Two patients with tamoxifen retinopathy were imaged with fluorescein angiography and OCT 3. Results Fluorescein angiography showed foveolar hyperfluorescence. OCT revealed a foveolar cystoid space with focal disruption of the photoreceptor line. There was no evidence of macular edema or thickening. Conclusions In both cases, OCT findings are not consistent with previous descriptions of tamoxifen retinopathy, based on fundus examination and fluorescein angiography, which include a description of macular edema. This new imaging suggests that tamoxifen maculopathy may include a ...

      Read Full Article
    19. CHOROIDAL GRANULOMAS VISUALIZED BY SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      CHOROIDAL GRANULOMAS VISUALIZED BY SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To assess the visualization of choroidal granulomas with swept-source optical coherence tomography angiography (OCTA). Methods: Consecutive patients with granulomatous choroiditis due to tuberculosis, sarcoidosis, or Vogt–Koyanagi–Harada disease underwent baseline OCTA images using a 12 × 12-mm field of view, and the choroidal slabs were analyzed by two independent examiners who counted the oval areas of flow void. Simultaneously, indocyanine green angiography (ICGA) and enhanced-depth imaging OCT were performed to mark visible choroidal changes corresponding to granulomatous lesions. The lesion areas on OCTA and ICGA were assessed using the in-built caliper tool. Results: Three hundred and one round-shaped areas ...

      Read Full Article
    20. Visibility of microvessels in Optical Coherence Tomography Angiography depends on angular orientation

      Visibility of microvessels in Optical Coherence Tomography Angiography depends on angular orientation

      OCT Angiography (OCTA) is a widespread tool for depth‐resolved imaging of chorioretinal vasculature with single microvessel resolution. To improve the clinical interpretation of OCTA, the conditions affecting visualization of microvessels must be defined. Here we inject a scattering plasma tracer (Intralipid) during OCTA imaging of the anesthetized rat eye. In the retina, we find that interlaminar (vertical) vessels that connect laminae have one‐fourth to one‐third the OCTA red blood cell to tracer (RBC‐to‐tracer) signal ratio of intralaminar (horizontal) vessels. This finding suggests that the OCTA signal from microvessels depends on angular orientation, making vertically‐oriented ...

      Read Full Article
    21. Cilioretinal arteries and macular vasculature in highly myopic eyes: an OCT–angiography-based study

      Cilioretinal arteries and macular vasculature in highly myopic eyes: an OCT–angiography-based study

      Purpose To determine the association between the presence of cilioretinal arteries and the macular vasculature in highly myopic eyes using optical coherence tomography angiography (OCTA). Design Retrospective, observational case series. Participants 481 highly myopic eyes of 481 patients. Methods Fundus photographs were reviewed to determine the presence of a cilioretinal artery and its distribution, based on whether its path or visible branches reached the region within 500 μm of the foveal center. The macular vasculature was analyzed in OCTA images, including the vessel density (VD), fractal dimension (FD), and foveal avascular zone (FAZ). The associations between the presence of a ...

      Read Full Article
    22. Quantifying the Separation Between the Retinal Pigment Epithelium and Bruch's Membrane using Optical Coherence Tomography in Patients with Inherited Macular Degeneration

      Quantifying the Separation Between the Retinal Pigment Epithelium and Bruch's Membrane using Optical Coherence Tomography in Patients with Inherited Macular Degeneration

      Purpose : To describe and quantify Bruch's membrane (BM) and retinal pigment epithelium (RPE) separation using spectral-domain (SD) optical coherence tomography (OCT) in patients affected by inherited macular degenerations associated with BM thickening. Methods : Patients with molecularly confirmed Sorsby fundus dystrophy (SFD), dominant drusen (DD), and late-onset retinal degeneration (L-ORD) were included in this retrospective study. Each disease was classed as early stage if subjects were asymptomatic, intermediate stage if they had nyctalopia alone, and late stage if they described loss of central vision. The main outcome was measurement of BM-RPE separation on SD-OCT. The BM-RPE separation measurements were compared ...

      Read Full Article
    23. Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope

      Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope

      Background/ims To compare the retinal vessel diameter measurements obtained from the swept-source optical coherence tomography angiography (OCTA; Plex Elite 9000, Carl Zeiss Meditec, USA) and adaptive optics ophthalmoscope (AOO; RTX1, Imagine Eyes, France). Methods Fifteen healthy subjects, 67% women, mean age (SD) 30.87 (6.19) years, were imaged using OCTA and AOO by a single experienced operator on the same day. Each eye was scanned using two OCTA protocols (3×3 mm 2 and 9×9 mm 2 ) and two to five AOO scans (1.2×1.2 mm 2 ). The OCTA and AOO scans were scaled to ...

      Read Full Article
    1-24 of 13176 1 2 3 4 ... 547 548 549 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (4 articles) Medical University of Vienna
    2. (4 articles) National Institutes of Health
    3. (4 articles) University College London
    4. (3 articles) Fudan University
    5. (3 articles) University of Milan
    6. (3 articles) UCLA
    7. (3 articles) Duke University
    8. (2 articles) University of Houston
    9. (2 articles) Seoul National University
    10. (2 articles) Stanford University
    11. (2 articles) The Chinese University of Hong Kong
    12. (2 articles) Singapore Eye Research Institute
  4. People in the News

    1. (2 articles) Srinivas R. Sadda
    2. (2 articles) Giovanni Gregori
    3. (2 articles) Philip J. Rosenfeld
    4. (2 articles) Pearse A. Keane
    5. (2 articles) Joseph A. Izatt
    6. (2 articles) Kirill V. Larin
    7. (1 articles) Vivek J. Srinivasan
    8. (1 articles) Sebastian M. Waldstein
    9. (1 articles) Ursula Schmidt-Erfurth
    10. (1 articles) Adnan Tufail
    11. (1 articles) Peter K. Kaiser
    12. (1 articles) William R. Freeman
  5. OCT Companies in the News

    1. (8 articles) Carl Zeiss Meditec
    2. (4 articles) Topcon Medical Systems
    3. (4 articles) Optovue
    4. (2 articles) Heidelberg Engineering
    5. (2 articles) Tomey Corporation
    6. (2 articles) Alcon
    7. (1 articles) Lumedica
    8. (1 articles) LighTopTech
    9. (1 articles) Imagine Eyes
    10. (1 articles) Haag-Streit
    11. (1 articles) Notal Vision