1. Articles in category: Ophthalmology

    1-24 of 11969 1 2 3 4 ... 497 498 499 »
    1. Notal Vision Diagnostic Clinic reports completion of 6 million ForeseeHome AMD home-monitoring tests

      Notal Vision Diagnostic Clinic reports completion of 6 million ForeseeHome AMD home-monitoring tests

      Notal Vision, Inc., a company focused on advancing eye care with precision medicine by extending disease management from the clinic to the home, celebrates the completion of six million patient tests performed with ForeseeHome, the first FDA-cleared home-monitoring device for patients with intermediate dry Age-related Macular Degeneration (AMD) at risk for developing wet AMD. ForeseeHome uses a patented technology, Preferential Hyperacuity Perimetry® (PHP), that can identify minute changes in the central 14 degrees of visual field before the patient has any visual symptoms. During the test, which takes about three minutes, the central macula is evaluated for changes in metamorphopsia ...

      Read Full Article
      Mentions: Notal Vision
    2. Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

      Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

      Elevated intraocular pressure (IOP) is an important risk factor for glaucoma. However, the role of IOP in glaucoma progression, as well as retinal physiology in general, remains incompletely understood. We demonstrate the use of visible light optical coherence tomography to measure retinal responses to acute IOP elevation in Brown Norway rats. We monitored retinal responses in reflectivity, angiography, blood flow, oxygen saturation (sO2 ), and oxygen metabolism over a range of IOP from 10 to 100 mmHg. As IOP was elevated, nerve fiber layer reflectivity was found to decrease. Vascular perfusion in the three retinal capillary plexuses remained steady until IOP ...

      Read Full Article
    3. Optical Coherence Tomography-Angiography of Different Choroidal Neovascularization Subtypes in Wet Age-related Macular Degeneration

      Optical Coherence Tomography-Angiography of Different Choroidal Neovascularization Subtypes in Wet Age-related Macular Degeneration

      Age-related macular degeneration is a leading cause of irreversible vision loss in individuals over 55 years of age worldwide. Conventionally, it is divided into two subtypes – dry (non-neovascular) and wet (neovascular) form. Neovascular age-related macular degeneration comprises only 10-15% of all patients but is responsible for more than 80% of blindness related to the disease. It requires early diagnosis and timely treatment. Fluorescein angiography is the current ‘gold standard’ for diagnosing neovascular forms. However, as an invasive procedure, it may be contraindicated in some circumstances and cause serious adverse effects. Optical coherence tomography-angiography is a relatively new, non-invasive and fast ...

      Read Full Article
    4. Optical Coherence Tomography Angiography of Macula in Chronic Anterior Ischaemic Optic Neuropathy Associated with Giant Cell Arteritis

      Optical Coherence Tomography Angiography of Macula in Chronic Anterior Ischaemic Optic Neuropathy Associated with Giant Cell Arteritis

      A 74-year-old man presented with bilateral optic nerve atrophy related to arteritic anterior ischaemic optic neuropathy (AION) which started 22 years ago. Atrophic papilla was noted in both eyes and optical coherence tomography showed thinning of the retinal nerve fibres layer as well as the macular ganglion cell complex. Optical coherence tomography angiography of the macula found a decreased density of the superficial capillary complex, whereas deep capillary complex was well-preserved. Inner retinal layer atrophy in chronic arteritic AION is followed by a loss of vascularisation in these layers as a consequence of the neurodegeneration.

      Read Full Article
    5. Optical coherence tomography angiography findings in preeclampsia

      Optical coherence tomography angiography findings in preeclampsia

      Objectives To investigate vascular density analysis in the superficial (SCP) and deep capillary plexus (DCP), foveal avascular zone (FAZ), peripapillary vascular density analysis (PPCVD), and peripapillary retinal nerve fiber thickness analysis (PPRNFL) using optical coherence tomography angiography (OCTA) in pregnant women with preeclampsia and to compare the obtained values with healthy pregnant and nonpregnant healthy individuals. Methods A total of 98 pregnant women (55 had preeclampsia, 43 were healthy pregnant women) and 38 healthy nonpregnant women of reproductive age were included in the study. The patients were divided into three groups. Group 1 consisted of pregnant women with preeclampsia, group ...

      Read Full Article
    6. Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography

      Evaluation of posterior vitreous detachment using ultrasonography and optical coherence tomography

      Purpose To compare the diagnostic ability of ultrasonography (US) and optical coherence tomography (OCT) in evaluating posterior vitreous detachment (PVD) status. Methods In total, 124 eyes in 63 patients were prospectively enrolled. Posterior vitreous detachment (PVD) status was evaluated by two examiners independently using US and OCT (transverse scan with/without peripapillary scan). By combining all examination results from both examiners, a final agreement on the PVD status was made. Inter‐observer agreement and inter‐examination agreement on PVD detection were evaluated. Results The inter‐observer agreement on PVD grading based on US was substantial (kappa = 0.628). The inter ...

      Read Full Article
    7. Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Optical coherence tomography angiography characteristics of acute retinal arterial occlusion

      Background To characterize the vascular changes in eyes within the acute phase of retinal arterial occlusion (RAO) by optical coherence tomography angiography (OCT-A) imaging. Methods This was a retrospective, observational study. Nineteen patients with RAO (symptom onset within 7 days) and 19 age and sex-matched normal control individuals were included. A comprehensive ophthalmic examination and OCT-A examination were conducted for all the patients. Results The vessel density of the superficial capillary plexus (SCP), deep capillary plexus (DCP), and area with a width of 300 μm around the FAZ (FD-300) was significantly reduced in RAO patients compared with that in the ...

      Read Full Article
      Mentions: Jing Xu
    8. Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)

      Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)

      Objective To elucidate the difference between choroidal thickness (CT) in primary open-angle glaucoma (POAG) and normal subjects and to compare the CT measured using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT). Methods and analysis This cross-sectional observational study included 25 eyes of 17 POAG subjects (cases) and 31 eyes of 20 normal subjects (controls). All the patients underwent complete ophthalmologic examination, enhanced depth imaging, SD-OCT and SS-OCT. In both controls and cases, the CT was measured in seven predetermined points in macular and peripapillary area and were compared. Results Choroid was significantly thicker on ...

      Read Full Article
    9. Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association with Intracranial Pressure

      Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association with Intracranial Pressure

      Purpose: Papilledema and peripapillary deformation of Bruch’s membrane(BM) are associated with elevated intracranial pressure(ICP). We have developed a novel methodology to measure these parameters using a radial optical coherence tomography(OCT) scan pattern and apply this to test the hypothesis that ICP is associated with volumetric features of ophthalmic structures. Methods: 6-radial OCT B-scans centered over the optic nerve head were acquired in 17 subjects(30 eyes) before lumbar puncture with measurement of ICP(range:10-55 cm H2O). Internal limiting membrane(ILM) and BM were segmented. Three definitions of BM were studied to account for imaging artifact ...

      Read Full Article
    10. Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma

      Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma

      Objective To evaluate the retina and optic nerve head (ONH) in canine eyes predisposed to glaucoma using optical coherence tomography (OCT). Animals Twenty‐five eyes (24 dogs). Methods Measures of peripapillary retinal, retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) thickness and ONH parameters were obtained in vivo by OCT of the unaffected eye in dogs diagnosed with unilateral primary glaucoma (predisposed; n = 12) and compared with measures of healthy control eyes (normal; n = 13). Repeatability and intrarater reliability were explored using intraclass correlation coefficients (ICC). Results Compared to normal eyes, predisposed eyes had a thinner retina in ...

      Read Full Article
    11. Quantification of choriocapillaris with OCTA: a comparison study

      Quantification of choriocapillaris with OCTA: a comparison study

      Purpose To demonstrate the variation in quantitative choriocapillaris (CC) metrics with various binarization approaches using optical coherence tomography angiography (OCTA). Design Retrospective, observational, cross-sectional case series. Methods 3x3 mm and 6x6 mm macular OCTA scans were obtained from normal eyes and from eyes with drusen secondary to AMD. The CC slab was extracted and the CC flow deficits (FDs) were segmented with two previously published algorithms: fuzzy C-means approach (FCM method) and Phansalkar’s local thresholding (Phansalkar method). Four different values for the radius were used in order to investigate the effect on the FD segmentation when using the Phansalkar ...

      Read Full Article
    12. Optical coherence tomography (OCT) data processing method, storage medium storing program for executing the OCT data processing method, and processing device

      Optical coherence tomography (OCT) data processing method, storage medium storing program for executing the OCT data processing method, and processing device

      An Optical Coherence Tomography (OCT) data processing apparatus includes an acquisition unit configured to acquire three dimensional (3-D) OCT data of an object to be inspected, a generation unit configured to generate a motion contrast image based on the 3-D OCT data, and a detection unit configured to detect a inner surface coordinate of a vessel wall based on position information of an edge of a vessel region in the motion contrast image.

      Read Full Article
    13. Ocular coherence tomography for the diagnosis of Descemet's detachment after deep sclerectomy and resolution after intracameral air injection

      Ocular coherence tomography for the diagnosis of Descemet's detachment after deep sclerectomy and resolution after intracameral air injection

      Purpose to report the use of optical coherence tomography (OCT) in a case of Descemet's membrane detachment (DMD) secondary to a nonpenetrating deep sclerectomy (NPDS) and the efficacy of intracameral air injection for management. Observations DMD was identified by anterior segment OCT (AS-OCT) in a 61-year-old male patient who was blind in the right eye and had advanced open angle glaucoma. This patient underwent NPDS in the left eye and developed localized corneal edema postoperatively. Air was injected into the anterior chamber resulting in reattachment of Descemet's membrane and resolution of corneal edema. Conclusions and Importance: This case ...

      Read Full Article
    14. Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

      Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

      This review will highlight recent insights into measuring retinal structure in Alzheimer’s disease (AD). A growing body of evidence indicates that disturbances in retinal blood flow and structure are related to cognitive function, which can severely impair vision. Optical coherence tomography (OCT) is an optical imaging technology that may allow researchers and physicians to gain deeper insights into retinal morphology and clarify the impact of AD on retinal health and function. Direct and noninvasive measurement of retinal morphology using OCT has provided useful diagnostic and therapeutic indications in several central nervous system (CNS) diseases, including AD, multiple sclerosis, and ...

      Read Full Article
    15. Comparison of conjunctival vascularity changes using optical coherence tomography angiography after trabeculectomy and phacotrabeculectomy

      Comparison of conjunctival vascularity changes using optical coherence tomography angiography after trabeculectomy and phacotrabeculectomy

      Purpose To compare bleb vascularity changes using optical coherence tomography angiography (OCT-A) between mitomycin-C (MMC)-augmented trabeculectomy and phacotrabeculectomy and to determine whether bleb vascularity measurements during preoperative and early postoperative periods could act as surrogate parameters to predict surgical outcomes. Methods We retrospectively reviewed data for 72 eyes from 72 glaucoma patients who underwent MMC-augmented trabeculectomy with/without cataract surgery. Bleb area scans were obtained using OCT-A during the preoperative period; 1, 2, 4, and 6 weeks postoperatively; and 2, 4, and 6 months postoperatively. For conjunctival vascularity analysis, a semi-automated program was used to calculate color and brightness ...

      Read Full Article
    16. Choroidal thickness measured with swept source optical coherence tomography in posterior staphyloma strongly correlates with axial length and visual acuity

      Choroidal thickness measured with swept source optical coherence tomography in posterior staphyloma strongly correlates with axial length and visual acuity

      Purpose To measure the choroidal thickness in patients with high myopia from staphyloma using swept source OCT (SS-OCT) in Early Treatment Diabetic Retinopathy Study (ETDRS) fields and compare to normal cohort. The study also evaluated the correlation between choroidal thickness with axial length and best-corrected visual acuity (BCVA). Methods In this prospective cross sectional study, 37 eyes of 20 patients with high myopia from staphyloma and 86 eyes of 43 normal subjects were included. In each eye, horizontal scans centered on the fovea (12 × 9 mm) were performed using SS-OCT (DRI-OCT, Topcon, Japan). Choroidal thickness in 9 ETDRS subfields, including ...

      Read Full Article
    17. Longitudinal detection of retinal alterations by visible and near-infrared optical coherence tomography in a dexamethasone-induced ocular hypertension mouse model

      Longitudinal detection of retinal alterations by visible and near-infrared optical coherence tomography in a dexamethasone-induced ocular hypertension mouse model

      The retina, as part of the central nervous system, has distinct anatomical and structural properties for its visual function. Light scattering spectroscopy, while widely used for tissue structural characterization and disease diagnosis, has been relatively unexplored in the living retina. Recently, we have developed a fiber-based visible and near-infrared optical coherence tomography system (vnOCT) for in vivo retinal imaging, to uniquely measure a spectroscopic marker (VN ratio) sensitive to nanoscale pathological changes. In the present study, we applied vnOCT in an animal model of glaucoma (dexamethasone-induced ocular hypertension mouse) and tested the capabilities of four optical markers, VN ratio, peripapillary ...

      Read Full Article
    18. Relationship between Neovascular Density in Swept Source-Optical Coherence Tomography Angiography and Signs of Activity in Exudative Age-Related Macular Degeneration

      Relationship between Neovascular Density in Swept Source-Optical Coherence Tomography Angiography and Signs of Activity in Exudative Age-Related Macular Degeneration

      Purpose . To assess the relationship between signs of activity in exudative neovascular age-related macular degeneration (nAMD) following anti-vascular endothelial growth factor (anti-VEGF) treatment and morphology of choroidal neovascularization (CNV) based on neovascular density as imaged using swept source-optical coherence tomography angiography (SS-OCTA) in a qualitative manner. Methods . A single-cohort retrospective data analysis from one tertiary eye care center. Seventy-seven eyes of 72 patients were included and their charts reviewed which had been started on intravitreal injections with anti-VEGF for nAMD at least one year prior to enrollment. Clinically active disease was evaluated by slit-lamp fundus examination and spectral domain-OCT B-scans ...

      Read Full Article
    19. Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

      Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

      The aim of this study was to assess the central macular imaging captured with an optical biometer based on full-eye-length Swept-Source OCT (SS-OCT) scan as a screening strategy for identifying macular diseases in patients scheduled for cataract surgery. 1,114 eyes of 749 consecutive patients underwent a biometrical examination with IOLMaster 700 SS-OCT technology (Carl Zeiss) and conventional Spectral-Domain OCT (SD-OCT) (Spectralis OCT, Heidelberg) device analysis on the same day. Seven examiners graded the scans individually in a full-masked mode. Twenty-five eyes were excluded for media opacities. Among the 1,089 included eyes, statistical analysis revealed a mean Kendall’s ...

      Read Full Article
    20. Detecting Retinal Nerve Fibre Layer Segmentation Errors on Spectral Domain-Optical Coherence Tomography with a Deep Learning Algorithm

      Detecting Retinal Nerve Fibre Layer Segmentation Errors on Spectral Domain-Optical Coherence Tomography with a Deep Learning Algorithm

      n this study we developed a deep learning (DL) algorithm that detects errors in retinal never fibre layer (RNFL) segmentation on spectral-domain optical coherence tomography (SDOCT) B-scans using human grades as the reference standard. A dataset of 25,250 SDOCT B-scans reviewed for segmentation errors by human graders was randomly divided into validation plus training (50%) and test (50%) sets. The performance of the DL algorithm was evaluated in the test sample by outputting a probability of having a segmentation error for each B-scan. The ability of the algorithm to detect segmentation errors was evaluated with the area under the ...

      Read Full Article
    21. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS IN TWO CASES OF SOLAR RETINOPATHY

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS IN TWO CASES OF SOLAR RETINOPATHY

      Purpose: To report optical coherence tomography angiography findings obtained in two patients with solar retinopathy . Methods: Two case reports. Results: Two patients presented with blurry vision after sun gazing during the recent solar eclipse and were found to have characteristic foveal lesions on examination and optical coherence tomography consistent with solar retinopathy . Optical coherence tomography angiography showed a focal area of nonperfusion of the choriocapillaris in the affected eyes. Conclusion: Changes to the choriocapillaris layer on optical coherence tomography angiography in two patients with solar retinopathy suggest that damage is not limited to the retina.

      Read Full Article
    22. International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      The International Ocular Circulation Society (IOCS) was co-founded by a group of leading researchers in America, Asia, and Europe in 2018. The inaugural meeting of the new Society will be hosted by David Huang, M.D. and Yali Jia, Ph.D. of the Casey Eye Institute in Portland Oregon on August 10, 2019. The meeting will present 28 papers and 35 posters on technologies on the topics of imaging and measurement of ocular blood flow and oxygen metabolism, vascular anatomy and physiology, and the roles of ocular circulation in retina, optic nerve, neurological, and systemic diseases. The Oregon Health & Science ...

      Read Full Article
    23. Lumedica Receives NIH Grant for Low Cost Retinal Optical Coherence Tomography for Point of Care Use

      Lumedica Receives NIH Grant for Low Cost Retinal Optical Coherence Tomography for Point of Care Use

      Lumedica Receives a 2019 NIH Grant for $499,978 for Low Cost Retinal Optical Coherence Tomography for Point of Care Use. The principal investigator is William Brown. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. The objective of this research is to create a clinical prototype of a new optical coherence tomography (OCT) system suitable for diagnostic retinal imaging at the point of care. The target system price will be one third the price of currently available research OCT systems while providing performance comparable to other entry level OCT imaging systems ...

      Read Full Article
    24. ZEISS Ophthalmic Digital Summit 2019

      ZEISS Ophthalmic Digital Summit 2019

      In partnership with ODwire, Carl Zeiss Meditec, Inc. and Carl Zeiss Vision invite you to the ZEISS Ophthalmic Digital Summit 2019 . This two-day complimentary program offers live sessions and an interactive product showcase—all within a virtual exhibit hall—designed to provide you with the latest technology innovations and clinical solutions for your practice. Taught by industry leaders , you'll get trained and informed on how the Integrated Diagnostic Imaging platform and ZEISS leading imaging technologies will help shape the future of your practice. Event attendees will also be eligible for special show promotions and discounts on ZEISS instruments.

      Read Full Article
    1-24 of 11969 1 2 3 4 ... 497 498 499 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (9 articles) Duke University
    2. (6 articles) Oregon Health & Science University
    3. (6 articles) University of Miami
    4. (5 articles) Center for Ophthalmic Optics and Lasers
    5. (5 articles) National Institutes of Health
    6. (4 articles) Massachusetts Eye and Ear Infirmary
    7. (4 articles) Harvard University
    8. (3 articles) University of Southern California
    9. (3 articles) University of Washington
    10. (2 articles) Tohoku University
    11. (2 articles) Fudan University
    12. (2 articles) L V Prasad Eye Institute
  4. People in the News

    1. (5 articles) David Huang
    2. (3 articles) Ruikang K. Wang
    3. (3 articles) Adam Wax
    4. (3 articles) Francesco Bandello
    5. (2 articles) Cynthia A. Toth
    6. (2 articles) Philip J. Rosenfeld
    7. (2 articles) Teresa C. Chen
    8. (2 articles) Benjamin J. Vakoc
    9. (2 articles) Sharon F. Freedman
    10. (2 articles) Joseph A. Izatt
    11. (2 articles) Bruno Lumbroso
    12. (2 articles) Mohamed Abou Shousha
  5. OCT Companies in the News

    1. (4 articles) Lumedica
    2. (3 articles) Carl Zeiss Meditec
    3. (2 articles) Bioptigen
    4. (1 articles) Heidelberg Engineering
    5. (1 articles) Canon Medical Systems
    6. (1 articles) Nidek
    7. (1 articles) Notal Vision
    8. (1 articles) Specsavers