1. Articles in category: Ophthalmology

    1-24 of 5999 1 2 3 4 ... 248 249 250 »
    1. Advanced Optical Coherence Tomography Applications for the Retina Specialist (CME Webinar Seires)

      Advanced Optical Coherence Tomography Applications for the Retina Specialist (CME Webinar Seires)

      Advances in retinal pharmacology have significantly improved outcomes for patients with a range of chronic retinal conditions, including age-related macular degeneration, macular edema, retinal vascular disorders and diseases of the vitreomacular interface. Maximizing the efficacy of available treatments requires the appropriate use of optical coherence tomography (OCT) to diagnose these conditions and to monitor the efficacy of treatment. In this webinar series, leading clinicians and researchers will discuss the role of OCT in detecting structural changes associated with a range of retinal diseases and provide clinical pearls on using tools such as thickness maps, automated change analysis and angiography in ...

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    2. Predictive Values of Optical Coherence Tomography (OCT) Parameters in Assessment of Glaucoma progression

      Predictive Values of Optical Coherence Tomography (OCT) Parameters in Assessment of Glaucoma progression

      Goal: the purpose of the current study was to estimate the predictive values of optical coherence tomography parameters in early, developed perimetric and terminal glaucoma. Methods: 180 eyes of 120 consecutive patients were evaluated in this retrospective cross sectional pilot study. Copernicus Spectral –domain optical coherence tomography with resolution of 3 mm obtained throught the optic nerve head were included. All examined eyes were divided to four groups (healthy,early, developed perimetric glaucoma and terminal glaucoma). The values of the thicknes of the retinal nerve fibre layer, the size of the disk, the volume of the cup, the E/D ...

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    3. Analysis of peripapilary retinal nerve fiber layer thickness of healthy Chinese from northwestern Shanghai using Cirrus HD-OCT

      Analysis of peripapilary retinal nerve fiber layer thickness of healthy Chinese from northwestern Shanghai using Cirrus HD-OCT

      AIM: To investigate peripapillary retinal nerve fiber layer (RNFL) thickness of healthy Chinese individuals from northwestern Shanghai using Cirrus HD-OCT (Carl Zeiss Meditec, Inc. Dublin, CA, USA). METHODS: The peripapillary RNFL thickness of 720 eyes from 360 healthy Chinese participants were measured using the Optic Disc Cube 200×200 protocol. Each eye was scanned 3 times. Global and each quadrant’s RNFL thickness around the optic nerve were compared between genders, and interocular differences were analyzed. The correlation between global RNFL thickness and age were also assessed in this study. RESULTS: The mean global, superior, nasal, inferior and temporal RNFL ...

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    4. OPTICAL COHERENCE TOMOGRAPHIC HYPERREFLECTIVE FOCI IN EARLY STAGES OF DIABETIC RETINOPATHY

      OPTICAL COHERENCE TOMOGRAPHIC HYPERREFLECTIVE FOCI IN EARLY STAGES OF DIABETIC RETINOPATHY

      Purpose: To analyze the presence of hyperreflective foci in Type 1 and Type 2 diabetic patients, separately, without clinically significant diabetic macular edema and visual impairment. Methods: Noninvasive, observational prospective study. Seventeen and 19 consecutive Type 1 and Type 2 diabetic patients (33 and 38 eyes), respectively, were recruited. All patients had no clinically significant diabetic macular edema or visual impairment. Two age- and sex-matched control groups were also included. Patients underwent an ophthalmologic examination including spectral domain optical coherence tomography. Hyperreflective foci were counted considering horizontal B-scan passing through the fovea. Results: On spectral domain optical coherence tomography, patients ...

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    5. OPTICAL COHERENCE TOMOGRAPHY-GUIDED RANIBIZUMAB INJECTION FOR CYSTOID MACULAR EDEMA IN WELL-CONTROLLED UVEITIS: Twelve-Month Outcomes

      OPTICAL COHERENCE TOMOGRAPHY-GUIDED RANIBIZUMAB INJECTION FOR CYSTOID MACULAR EDEMA IN WELL-CONTROLLED UVEITIS: Twelve-Month Outcomes

      Purpose: To determine whether serial ranibizumab injections are effective in the treatment of cystoid macular edema in patients with chronic controlled noninfectious uveitis. Methods: Five eyes of 5 patients were included in a prospective noncomparative therapeutic trial. They received intravitreal injections of ranibizumab at Day 0 and were followed monthly for 1 year. Injections were repeated monthly if persistent or new cystic edema manifested on optical coherence tomography. The primary outcome measure was the mean change in best-corrected visual acuity from baseline at 12 months. Secondary outcome measures included mean percentage change in central subfield retinal thickness (CST) and incidence ...

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    6. Retinal and choroidal thickness measurements using spectral domain optical coherence tomography in anterior and intermediate uveitis

      Retinal and choroidal thickness measurements using spectral domain optical coherence tomography in anterior and intermediate uveitis

      Background Macular edema is a common cause of visual loss at uveitic patients. The aim of our study was to investigate retinal and choroidal thickness at the macula in anterior (AU) and intermediate (IMU) uveitis and in healthy individuals using spectral domain optical coherence tomography (SD-OCT). Methods Case-control study of 21 patients with AU and 23 patients with IMU and 34 age-matched healthy controls was performed with Spectralis SD-OCT (Heidelberg Engineering, Germany). High resolution SD-OCT scans and macular mapping were applied for automated measurement of retinal thickness. Standardized, masked manual measurement of the choroidal thickness was performed in the center ...

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    7. Sina Farsiu: Biomedical Engineer Processes an Avalanche of Images

      Sina Farsiu: Biomedical Engineer Processes an Avalanche of Images

      Sina Farsiu wants to figure out how to peer into your soul . . . or at least your brain. An expert in designing computer image processing algorithms, Farsiu is an assistant professor of ophthalmology at Duke Medicine who recently accepted a primary appointment in the Pratt biomedical engineering department with the hopes of strengthening collaborations across the university. “When President Bush said he looked Vladimir Putin in the eye and got a sense of his soul, he was actually on to something,” said Farsiu, who has a long history of collaborating with peers in Duke’s engineering school. “The retina is part ...

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    8. OCT in the Management of Macular Degeneration - Ophthalmology Education Lab

      OCT in the Management of Macular Degeneration - Ophthalmology Education Lab

      Advances in retinal pharmacology have significantly improved outcomes for patients with a range of chronic retinal conditions, including age-related macular degeneration, macular edema, retinal vascular disorders and diseases of the vitreomacular interface. Maximizing the efficacy of available treatments requires the appropriate use of optical coherence tomography (OCT) to diagnose these conditions and to monitor the efficacy of treatment. In this webinar series, leading clinicians and researchers will discuss the role of OCT in detecting structural changes associated with a range of retinal diseases and provide clinical pearls on using tools such as thickness maps, automated change analysis and angiography in ...

      Read Full Article
    9. Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University

      Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University

      The Center for Ophthalmic Optics and Lasers www.COOLLab.net , Casey Eye Institute, Oregon Health & Science University, is seeking outstanding candidates for the following position in optical imaging research in the field of ophthalmology. Post-Doc (software): optical signal processing, image processing Requirements: PhD degree in a relevant discipline (Biomedical Engineering, Medical Physics, computer science, applied mathematics) is required. Solid background in optical signal processing, (medical) image analysis, segmentation and/or image registration are essential. Experiences in imaging (scanning laser ophthalmoscopy, angiography, microscopy, oximetry, adaptive optics), and software development (GPU programming) are also desirable. The successful candidate will be supervised by ...

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    10. Corneal Topographic Analysis of Patients With Mooren Ulcer Using 3-Dimensional Anterior Segment Optical Coherence Tomography

      Corneal Topographic Analysis of Patients With Mooren Ulcer Using 3-Dimensional Anterior Segment Optical Coherence Tomography

      Purpose: To investigate the corneal topography and visual function of patients with Mooren ulcer using 3-dimensional anterior segment optical coherence tomography (3-D AS-OCT). Methods: Fourteen eyes of 9 patients with Mooren ulcer were studied. Pachymetric and axial power maps were obtained by 3-D AS-OCT. The axial power maps were classified into 3 patterns by visual inspection. The distribution of the corneal dioptric power was analyzed by Fourier harmonic expansion. The magnitudes of the spherical component, asymmetry, regular astigmatism, higher-order irregularity, and radial distance from the corneal vertex to the thinnest point of the lesion were determined. Results: The axial power ...

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    11. A survey of current and anticipated use of standard and specialist equipment by UK optometrists

      A survey of current and anticipated use of standard and specialist equipment by UK optometrists

      Purpose To investigate current and anticipated use of equipment and information technology (IT) in community optometric practice in the UK, and to elicit optometrists' views on adoption of specialist equipment and IT. Methods An anonymous online questionnaire was developed, covering use of standard and specialist diagnostic equipment, and IT. The survey was distributed to a random sample of 1300 UK College of Optometrists members. Results Four hundred and thirty-two responses were received (response rate = 35%). Enhanced (locally commissioned) or additional/separately contracted services were provided by 73% of respondents. Services included glaucoma repeat measures (30% of respondents), glaucoma referral refinement ...

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    12. Relationship between Optical Coherence Tomography and Electrophysiology of the Visual Pathway in Non-Optic Neuritis Eyes of Multiple Sclerosis Patients

      Relationship between Optical Coherence Tomography and Electrophysiology of the Visual Pathway in Non-Optic Neuritis Eyes of Multiple Sclerosis Patients

      Purpose Loss of retinal ganglion cells in in non-optic neuritis eyes of Multiple Sclerosis patients (MS-NON) has recently been demonstrated. However, the pathological basis of this loss at present is not clear. Therefore, the aim of the current study was to investigate associations of clinical (high and low contrast visual acuity) and electrophysiological (electroretinogram and multifocal Visual Evoked Potentials) measures of the visual pathway with neuronal and axonal loss of RGC in order to better understand the nature of this loss. Methods Sixty-two patients with relapsing remitting multiple sclerosis with no previous history of optic neuritis in at least one ...

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    13. Discriminating between Glaucoma and Normal Eyes Using Optical Coherence Tomography and the ‘Random Forests’ Classifier

      Discriminating between Glaucoma and Normal Eyes Using Optical Coherence Tomography and the ‘Random Forests’ Classifier

      Purpose To diagnose glaucoma based on spectral domain optical coherence tomography (SD-OCT) measurements using the ‘Random Forests’ method. Methods SD-OCT was conducted in 126 eyes of 126 open angle glaucoma (OAG) patients and 84 eyes of 84 normal subjects. The Random Forests method was then applied to discriminate between glaucoma and normal eyes using 151 OCT parameters including thickness measurements of circumpapillary retinal nerve fiber layer (cpRNFL), the macular RNFL (mRNFL) and the ganglion cell layer-inner plexiform layer combined (GCIPL). The area under the receiver operating characteristic curve (AROC) was calculated using the Random Forests method adopting leave-one-out cross validation ...

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    14. Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography Findings in Choroidal Neurofibromatosis

      Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography Findings in Choroidal Neurofibromatosis

      The authors report multimodal imaging findings, including enhanced depth imaging-optical coherence tomography, in an affected child with choroidal neurofibromatosis. Novel features such as choroidal vessel compression from choroidal nodules related to neurofibromatosis type 1 and an increased subfoveal choroidal thickness are identified. This is the first report to use EDI-OCT to analyze choroidal features in neurofibromatosis type 1.

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    15. Importance of Optical Coherence Tomography Grows

      Importance of Optical Coherence Tomography Grows

      Optical coherence tomography (OCT) has become essential to the practice of ophthalmology, offering superior resolution of the retina and some of the adjacent tissues for diagnosis and treatment of eye diseases. New OCT modalities have now been assimilated into ophthalmic oncology to help track the status of ocular and periocular tumors through retinal symptoms. “ Optical coherence tomography imaging of ocular and periocular tumours ,” a review of newer OCT modalities including anterior segment (AS), ultra-high resolution (UHR), spectral domain (SD) and enhanced depth imaging (EDI), describes the current advantages and limitations of their use. Use of OCT shows mixed results The ...

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      Mentions: Cleveland Clinic
    16. True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe

      True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe

      Scanning laser ophthalmoscopes (SLOs) are able to achieve superior contrast and axial sectioning capability compared to fundus photography. However, SLOs typically use monochromatic illumination and are thus unable to extract color information of the retina. Previous color SLO imaging techniques utilized multiple lasers or narrow band sources for illumination, which allowed for multiple color but not “true color” imaging as done in fundus photography. We describe the first “true color” SLO, handheld color SLO, and combined color SLO integrated with a spectral domain optical coherence tomography (OCT) system. To achieve accurate color imaging, the SLO was calibrated with a color ...

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    17. Correlation Between the Findings of Optical Coherent Retinal Tomography (OCT), Stereo Biomicroscopic Images from Fundus of an Eye and Values from Visual Acuity of Diabetic Macular Edema

      Correlation Between the Findings of Optical Coherent Retinal Tomography (OCT), Stereo Biomicroscopic Images from Fundus of an Eye and Values from Visual Acuity of Diabetic Macular Edema

      Introduction: Diabetic maculopathy is the major cause of reduced visual acuity in patients with non-proliferative diabetic retinopathy and occurs on average in 29% of patients who have diabetes for 20 or more years. The aim: The aim of this study is to re examine the correlation between the findings of optical coherence retinal tomography, stereo biomicroscopic images from fundus of an eye and values from visual acuity of diabetic macular edema. In addition, the aim is to show the importance of various ophthalmic tests for establishing diagnosis in time. Material and methods: The research sample consisted of 90 subjects-patients from ...

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    18. Collaboration aims to reduce, treat vision problems in astronauts

      Collaboration aims to reduce, treat vision problems in astronauts

      To reduce and better treat spaceflight-induced visual impairment, University of Houston (UH) optometrists are collaborating on a NASA study that examines ocular changes seen in a number of astronauts. The research, developed by Heidelberg Engineering, uses Spectralis® Optical Coherence Tomography (OCT), which is a technique for obtaining subsurface images of translucent or opaque materials at a resolution equivalent to a low-power microscope. OCT effectively images reflections from within tissue to provide cross-sectional views. This technology is being used to investigate changes in visual acuity, intraocular pressure, the optic nerve and retinal structures in astronauts exposed to long-duration microgravity aboard the ...

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    19. Can optical coherence tomography predict early retinal microvascular pathology in type 1 diabetic adolescents without minimal diabetic retinopathy? A single-centre study

      Can optical coherence tomography predict early retinal microvascular pathology in type 1 diabetic adolescents without minimal diabetic retinopathy? A single-centre study

      Background: Optical coherence tomography (OCT) has been proven useful in measuring retinal thickness and volumes in patients with diabetes. Objective: To test whether OCT is able to identify early retinal changes and its potential correlations with metabolic parameters and other microvascular complications. Patients and methods: Thirty patients with type 1 diabetes without minimal diabetic retinopathy (MDR) (17 males, 13 females, aged 14.3±2.4 years) compared with age-matched healthy volunteers were examined with OCT. Diabetes duration, anthropometric measurements, HbA 1c , other microvascular complications (nephropathy, autonomic and peripheral neuropathy) and total serum cholesterol were determined. Results: No statistically significant differences ...

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    20. Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: Commentary

      Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: Commentary

      There is no doubt that optical coherence tomography (OCT) has been an extremely exciting development for medicine and for multiple sclerosis (MS). The value of OCT as a diagnostic tool has been demonstrated and it has been to shown to identify patients with highly active disease (but magnetic resonance imaging (MRI) does both better). Its possible use as an instrument to measure neurodegeneration over time is perhaps the application most welcome to MS neurologists. Readers are directed to a systematic review of OCT 1 and a discussion of the potential and the problems associated with OCT by Green. 2 An ...

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    21. Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: Yes

      Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: Yes

      Magnetic resonance imaging (MRI) of the brain is the most widely established imaging modality for monitoring multiple sclerosis (MS). Although conventional MRI parameters such as the development of new T2 lesions and/or contrast-enhancing lesions are sensitive to inflammatory disease activity, the association between MRI markers of inflammation and disability progression in MS is modest. 1 Conversely, MRI measures of neurodegeneration, such as whole-brain atrophy, correlate well with disability progression, 2 with neurodegeneration considered the principal pathological substrate underlying disability in MS. MRI segmentation techniques also enable the measurement of brain substructure volumes. Gray matter (GM) atrophy is now recognized ...

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    22. Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: No

      Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: No

      Optical coherence tomography (OCT) is an exciting technique that has been applied to multiple sclerosis (MS) research for around the last 10 years. OCT enables rapid, non-invasive in vivo measurement of retinal nerve fibre layer (RNFL) thickness, reflecting neuroaxonal density within the optic nerve. Early studies applied to post-acute optic neuritis 1 demonstrate neuroaxonal loss. Further research extended the scope of OCT, finding that its measures appeared to be a useful surrogate of generalised brain axonal loss in MS patients; progressive RNFL thinning was evident even in the absence of a history of optic neuritis, 2 and RNFL thickness was ...

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    23. Effects of Sex and Age on the Normal Retinal and Choroidal Structures on Optical Coherence Tomography

      Effects of Sex and Age on the Normal Retinal and Choroidal Structures on Optical Coherence Tomography

      Optical coherence tomography (OCT) has become an essential tool in ophthalmology. Advances in OCT technology have made it possible to measure the thickness of the retina, specific retinal layers, and the choroid. In the present study, the body of the literature documenting the normal retinal and choroidal thickness are reviewed and the effects of sex, age, and axial length on retinal/choroidal thickness are discussed. Macular, retinal layer, and choroidal thickness measured on OCT images in normal eyes showed significant variations by sex and age. Macular retinal thickness was greater in men than in women, especially in the center, inner ...

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