1. Articles in category: Ophthalmology

    1-24 of 6756 1 2 3 4 ... 280 281 282 »
    1. In vivo volumetric depth-resolved vasculature imaging of human limbus and sclera with 1μm swept source phase-variance optical coherence angiography

      In vivo volumetric depth-resolved vasculature imaging of human limbus and sclera with 1μm swept source phase-variance optical coherence angiography

      We present in vivo volumetric depth-resolved vasculature images of the anterior segment of the human eye acquired with phase-variance based motion contrast using a high-speed (100 kHz, 10 5 A-scans/s) swept source optical coherence tomography system (SSOCT). High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. The human corneo–scleral junction and sclera were imaged with swept source phase-variance optical coherence angiography and compared with slit lamp images from the same eyes of normal subjects. Different features of the rich vascular system in the conjunctiva and episclera were visualized and described. This system ...

      Read Full Article
    2. Staging of development in Terrien's degeneration based on corneal curvatures detected by optical coherence tomography

      Staging of development in Terrien's degeneration based on corneal curvatures detected by optical coherence tomography

      Purpose We aimed to explore a new classification system based on the change of focal corneal curvatures and corneal thickness in Terrien’s corneal degeneration with optical coherence tomography. Methods This was a cross-sectional study. Ninety eyes of 59 patients with Terrien’s degeneration were examined with slit lamp biomicroscopy, Orbscan II corneal tomography and the Visante OCT system, and were staged according to Süveges’s classification. Results The ratio of female to male patients was 1.57:1. The ratio of bilateral to unilateral lesions was 1.27:1. The occurrence of bilateral lesion was higher in males ...

      Read Full Article
    3. Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis

      Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis

      PURPOSE: To evaluate the anterior keratoprosthesis-cornea interface in eyes with Boston type I keratoprosthesis (Kpro). METHODS: In a prospective non-interventional study, patients with Boston type I Kpro underwent ultra-high resolution optical coherence tomography (UHR-OCT) evaluation. The images were used to measure and describe characteristics of the anterior keratoprosthesis-cornea interface, epithelial interaction at the keratoprosthesis edge and the keratoprosthesis-cornea interface gap. RESULTS: Ten patients including 4 male and 6 female subjects with different preoperative diagnoses, i.e. 8 multiple corneal graft failures and 2 immunological ocular surface diseases, were studied. Mean age was 62.1 ± 20.0 (range, 33.0-83.0 ...

      Read Full Article
    4. Subretinal fluid in eyes with active ocular toxoplasmosis observed using spectral domain optical coherence tomography

      Subretinal fluid in eyes with active ocular toxoplasmosis observed using spectral domain optical coherence tomography

      Purpose To describe the clinical finding of subretinal fluid (SRF) in the posterior pole by spectral domain optical coherence tomography (SD-OCT) in eyes with active ocular toxoplasmosis (OT). Design Retrospective case series. Participants Thirty-eight eyes from 39 patients with active OT. Methods Eyes with active OT which underwent SD-OCT were reviewed. SRFs in the posterior pole were further analyzed. Main Outcome Measures Presence of SRF; its accompanying features, e.g. retinal necrosis, cystoid macular edema (CME), choroidal neovascularization (CNV); and longitudinal changes of SRF, including maximum height and total volume before and after treatment. Results SRF presented in 45.5 ...

      Read Full Article
    5. Interobserver agreement in detecting spectral-domain optical coherence tomography features of diabetic macular edema

      Interobserver agreement in detecting spectral-domain optical coherence tomography features of diabetic macular edema

      Purpose To evaluate interobserver agreement for the detection of spectral-domain optical coherence tomography (SDOCT) features of diabetic macular edema (DME). Method Cross-sectional study in which 2 retinal specialists evaluated SDOCT scans from eyes receiving treatment for DME. Scans from 50 eyes with DME of 39 patients were graded for features of DME including intra-retinal fluid (IRF), diffuse retinal oedema (DRE), hyper-reflective foci (HRF), subretinal fluid (SRF), macular fluid and vitreomacular traction (VMT). Features were graded as present or absent at zones involving the fovea, 1mm from the fovea and the whole scan of 49 line scans. Analysis was performed using ...

      Read Full Article
    6. Spectral-domain optical coherence tomography findings of peripapillary staphyloma.

      Spectral-domain optical coherence tomography findings of peripapillary staphyloma.

      A 10-year-old girl presented with blurred vision in her right eye since birth. Birth, developmental and medical histories were otherwise unremarkable. Her best corrected visual acuity was 20/30 and 20/20 in the right and left eyes, respectively, with bilateral mild myopia (−3.5 dioptres). Anterior segment, lens, ocular motility, Ishihara test and intraocular pressure were normal. Relative afferent papillary defect was negative. Normal fundus was found in the left eye. Right fundus photography revealed large peripapillary atrophy (deep cupping surrounding optic disc especially in the inferior side) with 6 disc diameters in width surrounded by pigmented ring with ...

      Read Full Article
    7. Photopic full-field electroretinography and optical coherence tomography in type 1 diabetic retinopathy

      Photopic full-field electroretinography and optical coherence tomography in type 1 diabetic retinopathy

      Purpose The purpose of this study was to evaluate the role of photopic full-field electroretinography (ERG) and retinal thickness measurements by spectral-domain optical coherence tomography (SD-OCT) in the assessment of disease severity in type 1 diabetic retinopathy. Methods A population-based cohort of 151 patients with type 1 diabetes underwent a complete ophthalmic examination, including photopic full-field ERG and SD-OCT for retinal thickness measurements. Stereoscopic fundus photographs were taken according to the Early Treatment Diabetic Retinopathy Study protocol, and the classification of diabetic retinopathy was based on the International Clinical Diabetic Retinopathy Disease Severity Scale. Associations between photographically determined retinopathy level ...

      Read Full Article
    8. Intraoperative Optical Coherence Tomography-Assisted Descemet Membrane Endothelial Keratoplasty in the DISCOVER Study

      Intraoperative Optical Coherence Tomography-Assisted Descemet Membrane Endothelial Keratoplasty in the DISCOVER Study

      Purpose To investigate the utility of intraoperative optical coherence tomography (OCT) for Descemet Membrane Endothelial Keratoplasty (DMEK) surgery. Design Prospective consecutive interventional case series. Methods DISCOVER (NCT02423213) is a prospective consecutive interventional case series examining the feasibility and utility microscope-integrated intraoperative OCT in ophthalmic surgery. This report focuses on those eyes in the DISCOVER study undergoing DMEK surgery. The eight cases were the first DMEK cases performed by the primary surgeon (J.M.G.) with microscope integrated intraoperative OCT feedback (Rescan 700, Carl Zeiss Meditec). Qualitative OCT analysis was performed at multiple surgeon-defined time points, including host and donor tissue ...

      Read Full Article
    9. Repeatability of Corneal Phase Retardation Measurements by Polarization-Sensitive Optical Coherence Tomography

      Repeatability of Corneal Phase Retardation Measurements by Polarization-Sensitive Optical Coherence Tomography

      Purpose. Polarization-sensitive optical coherence tomography (PS-OCT) can evaluate internal tissue structures of the cornea, such as collagen fibers, by phase retardation measurement. In this study, we assessed the repeatability of corneal phase retardation measurements using anterior segment PS-OCT. Methods. A total of 173 eyes of 173 patients were measured using PS-OCT. In total, 58 eyes of young subjects with normal corneas, 28 eyes of old subjects with normal corneas, 26 eyes with corneal dystrophy or degeneration, 37 eyes with corneal transplantation, and 24 eyes with keratoconus were evaluated. The 3-mm diameter average of en face phase retardation of the posterior ...

      Read Full Article
    10. Retinal Nerve Fibre Layer Measurements in Normal Eyes in Zaria Using Optical Coherence Tomography

      Retinal Nerve Fibre Layer Measurements in Normal Eyes in Zaria Using Optical Coherence Tomography

      Purpose: To determine the retinal nerve fiber layer (RNFL) measurements in normal eyes in Zaria and to investigate the effect of age and axial length on RNFL thickness. Materials and Methods Forty eyes of 40 healthy subjects aged between 18 and 73 underwent peripapillary RNFL thickness measurement by a series of three circular scans with a 3.4 mm diameter (Stratus optical coherence tomography, RNFL thickness 3.4 acquisition protocol). The mean RNFL values were correlated with age and axial length. The statistical analysis used was Pearson's coefficient of correlation, linear regression, and paired t -test with the analyse-it ...

      Read Full Article
    11. Staging of development in Terrien’s degeneration based on corneal curvatures detected by optical coherence tomography

      Staging of development in Terrien’s degeneration based on corneal curvatures detected by optical coherence tomography

      Purpose We aimed to explore a new classification system based on the change of focal corneal curvatures and corneal thickness in Terrien’s corneal degeneration with optical coherence tomography. Methods This was a cross-sectional study. Ninety eyes of 59 patients with Terrien’s degeneration were examined with slit lamp biomicroscopy, Orbscan II corneal tomography and the Visante OCT system, and were staged according to Süveges’s classification. Results The ratio of female to male patients was 1.57:1. The ratio of bilateral to unilateral lesions was 1.27:1. The occurrence of bilateral lesion was higher in males ...

      Read Full Article
    12. Ganglion Cell-Inner Plexiform Layer Thickness in Retinal Diseases: Repeatability Study of Spectral Domain Optical Coherence Tomography

      Ganglion Cell-Inner Plexiform Layer Thickness in Retinal Diseases: Repeatability Study of Spectral Domain Optical Coherence Tomography

      Purpose To analyze the repeatability of measuring the thickness of the ganglion cell inner-plexiform layer using spectral domain optical coherence tomography by auto-segmentation in various retinal diseases. Design Test-retest reliability analysis Methods 180 patients who visited our clinic between April and December 2013 were included. An experienced examiner obtained two consecutive measurements from a macular cube 512 × 128 scan. The patients were divided into three groups according to central macular thickness. Repeatability was determined by comparing the average, minimum, and six sectoral ganglion cell inner-plexiform layer thickness values among groups. Results Data from 165 of the 180 patients were included ...

      Read Full Article
    13. Association of Choroidal Neovascularization and Central Serous Chorioretinopathy With Optical Coherence Tomography Angiography

      Association of Choroidal Neovascularization and Central Serous Chorioretinopathy With Optical Coherence Tomography Angiography

      Importance Choroidal neovascularization (CNV) is a major cause of vision loss in chronic central serous chorioretinopathy (CSCR). Detecting CNV using fluorescein angiography (FA) may be challenging owing to the coexistence of features related to the primary diagnosis of CSCR. Optical coherence tomography angiography (OCTA) allows noninvasive visualization of retinal and choroidal vasculature via motion contrast and may contribute to the unequivocal diagnosis of CNV in this population. Objective To evaluate the sensitivity of spectral-domain OCTA in detecting CNV associated with chronic CSCR. Design, Setting, and Participants Observational cross-sectional study including 23 patients (27 eyes) who presented at the New England ...

      Read Full Article
    14. Evaluation of the Lower Punctum Parameters and Morphology Using Spectral Domain Anterior Segment Optical Coherence Tomography

      Evaluation of the Lower Punctum Parameters and Morphology Using Spectral Domain Anterior Segment Optical Coherence Tomography

      Purpose . To study features of the lower punctum in normal subjects using spectral domain anterior segment optical coherence tomography (SD AS-OCT). Methods . Observational cross-sectional study that included 147 punctae (76 subjects). Punctae were evaluated clinically for appearance, position, and size. AS-OCT was used to evaluate the punctal shape, contents, and junction with the vertical canaliculus. Inner and outer diameters as well as depth were measured. Results . 24 males and 52 females (mean age  y) were included. Lower punctum was perceived by OCT to be an area with an outer diameter (mean   μ m), inner diameter (mean   μ m), and depth (mean   μ m ...

      Read Full Article
    15. First International OCT Angiography Summit, Portland Oregon, July 25, 2015

      First International OCT Angiography Summit, Portland Oregon, July 25, 2015

      The OCT Angiography Summit CME conference introduces the new no-injection, dye-free imaging technology to the clinical audience. OCT angiography detects the intrinsic motion contrast of blood cells and therefore does not require the injection of extrinsic contrast such as fluorescein or ICG dye. This breakthrough technology is capable of three-dimensional imaging of capillary dropout or pathologic vessel growth in the leading cause of blindness: age-related macular degeneration, diabetic retinopathy, and glaucoma. This technology may likely lead to earlier diagnosis and better treatment decisions. Meeting link http://www.octangio.net/#!oct-angiography-summit/mainPage

      Read Full Article
    16. EVALUATION OF RETINAL NERVE FIBER LAYER THICKNESS IN ASYMMETRIC GLAUCOMA AMONG INDIAN POPULATION

      EVALUATION OF RETINAL NERVE FIBER LAYER THICKNESS IN ASYMMETRIC GLAUCOMA AMONG INDIAN POPULATION

      Context: Asymmetric glaucoma provides the opportunity to study effects of varying severity of glaucoma in the same subject. Retinal Nerve Fibre Layer thickness (RNFL) measurement and comparison between better and worse eye may provide useful inputs in diagnosis and monitoring progress of glaucoma. Aims: To measure the Retinal Nerve Fibre Layer thickness in asymmetric glaucoma by stratus OCT and GDx VCC and compare between affected and less affected eye. Settings and design: This prospective study was conducted at Regional Institute of Ophthalmology, Kolkata from September 2007 to September 2009. Method : 50 glaucoma patients were enrolled in the study who manifested ...

      Read Full Article
    17. Outer Retinal Layers as Predictors of Vision Loss

      Outer Retinal Layers as Predictors of Vision Loss

      Optical coherence tomography is a well-established diagnostic imaging technique that allows both qualitative (morphology and reflectivity) and quantitative (thickness, mapping and volume) analyses of the retinal architecture. 1,2 Since OCT has become available, correlations between anatomy on OCT and visual function have been investigated in a number of retinal diseases. 3-8 Retinal thickness parameters as assessed by OCT have been studied extensively in clinical trials, however only modest correlation between these quantitative parameters and visual acuity among a variety of retinal diseases has been established. 3,4,9-11 Advances in OCT technology, most importantly the advent of spectral-domain OCT ...

      Read Full Article
    18. Optical coherence tomographic apparatus, control method for optical coherence tomographic apparatus and storage medium

      Optical coherence tomographic apparatus, control method for optical coherence tomographic apparatus and storage medium

      An optical coherence tomographic apparatus includes a unit configured to perform tracking of an eye to be examined based on a plurality of images of the eye which are obtained at different times, and a control unit configured to control the unit which performs the tracking in a case where a plurality of tomographic images of the eye are obtained.

      Read Full Article
    19. Three-dimensional retina image generation device

      Three-dimensional retina image generation device

      An optical coherence eye-fundus tomography device has a high resolution and a good operability, as well as be miniaturized and be produced at a low cost. The optical coherence eye-fundus tomography device includes: a light source unit which emits a source light beam; a reference-light unit which reflects a reference light beam; an inspection unit which illuminates an object with an object scanning light beam, reflected the object scanning light beam; and a detection unit which obtains a tomographic image of the object on the basis of the interference light beam produced by interfering the reflected reference light beam with ...

      Read Full Article
    20. Choroidal Thickness Analysis in Patients with Usher Syndrome Type 2 Using EDI OCT

      Choroidal Thickness Analysis in Patients with Usher Syndrome Type 2 Using EDI OCT

      To portray Usher Syndrome type 2, analyzing choroidal thickness and comparing data reported in published literature on RP and healthy subjects. Methods . 20 eyes of 10 patients with clinical signs and genetic diagnosis of Usher Syndrome type 2. Each patient underwent a complete ophthalmologic examination including Best Corrected Visual Acuity (BCVA), intraocular pressure (IOP), axial length (AL), automated visual field (VF), and EDI OCT. Both retinal and choroidal measures were measured. Statistical analysis was performed to correlate choroidal thickness with age, BCVA, IOP, AL, VF, and RT. Comparison with data about healthy people and nonsyndromic RP patients was performed. Results ...

      Read Full Article
    21. Applying an Open-Source Segmentation Algorithm to Different OCT Devices in Multiple Sclerosis Patients and Healthy Controls: Implications for Clinical Trials

      Applying an Open-Source Segmentation Algorithm to Different OCT Devices in Multiple Sclerosis Patients and Healthy Controls: Implications for Clinical Trials

      Background . The lack of segmentation algorithms operative across optical coherence tomography (OCT) platforms hinders utility of retinal layer measures in MS trials. Objective . To determine cross-sectional and longitudinal agreement of retinal layer thicknesses derived from an open-source, fully-automated, segmentation algorithm, applied to two spectral-domain OCT devices. Methods . Cirrus HD-OCT and Spectralis OCT macular scans from 68 MS patients and 22 healthy controls were segmented. A longitudinal cohort comprising 51 subjects (mean follow-up: 1.4 ± 0.9 years) was also examined. Bland-Altman analyses and interscanner agreement indices were utilized to assess agreement between scanners. Results . Low mean differences (−2.16 to ...

      Read Full Article
    22. Measurement of the Distance Between the Limbus and Insertion of Extraocular Muscles Using Anterior Segment Optical Coherence Tomography

      Measurement of the Distance Between the Limbus and Insertion of Extraocular Muscles Using Anterior Segment Optical Coherence Tomography

      Study designed to determine the ability and accuracy of anterior segment optical coherence tomography (AS-OCT) to measure the distance between the corneoscleral limbus and the insertion site of the extraocular muscles (EOM) in adults with and without previous strabismus surgery. And to compare in surgical patients the pre-operative AS-OCT limbal-muscle insertion distance measurement to the intraoperative limbal-muscle insertion measurement using calipers (gold standard).

      Read Full Article
    1-24 of 6756 1 2 3 4 ... 280 281 282 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (6 articles) Oregon Health & Science University
    2. (5 articles) University of Miami
    3. (4 articles) Tufts University
    4. (4 articles) Center for Ophthalmic Optics and Lasers
    5. (3 articles) Thomas Jefferson University
    6. (3 articles) University College London
    7. (3 articles) National Institutes of Health
    8. (2 articles) Johns Hopkins University
    9. (2 articles) Sun Yat-Sen University
    10. (2 articles) Chungnam National University Hospital
    11. (2 articles) UCLA
    12. (2 articles) University of Tsukuba
  4. People in the News

    1. (6 articles) David Huang
    2. (2 articles) Srinivas R. Sadda
    3. (2 articles) Peter A. Calabresi
    4. (2 articles) Yoshiaki Yasuno
    5. (2 articles) Jay S. Duker
    6. (2 articles) Andre J. Witkin
    7. (2 articles) Bruno Lumbroso
    8. (2 articles) Carol L. Shields
    9. (2 articles) Marco Rispoli
    10. (2 articles) Nadia K. Waheed
    11. (1 articles) Jean-Marie Parel
    12. (1 articles) Giovanni Staurenghi
  5. OCT Companies in the News

    1. (6 articles) Carl Zeiss Meditec
    2. (4 articles) Heidelberg Engineering
    3. (2 articles) Topcon Medical Systems
    4. (1 articles) Wavelength Electronics
    5. (1 articles) Tomey Corporation
    6. (1 articles) Optovue
    7. (1 articles) LenSx
    8. (1 articles) Nidek
    9. (1 articles) Canon Medical Systems
  6. OCT Products in the News

    1. (5 articles) Zeiss Cirrus HD-OCT
    2. (4 articles) Heidelberg Spectralis
    3. (3 articles) Zeiss Visante OCT
    4. (2 articles) Zeiss Stratus OCT
    5. (1 articles) Topcon DRI OCT-1 Atlantis
    6. (1 articles) Optovue RTVue-100
    7. (1 articles) Tomey SS-1000 CASIA