Popular Articles
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OCT Products in the News
(300 articles) Zeiss Stratus OCT
(111 articles) Zeiss Cirrus HD-OCT
(90 articles) Zeiss Visante OCT
(77 articles) Heidelberg Spectralis
(65 articles) Optovue RTVue-100
(30 articles) Topcon 3D OCT-1000
(18 articles) Ophthalmic Technologies Spectral OCT/SLO
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Organizations in the News
(102 articles) University of Southern California
(85 articles) University of Miami
(67 articles) Medical University of Vienna
(59 articles) University of Pittsburgh
(54 articles) Massachusetts Institute of Technology
(46 articles) Tufts University
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Comparative study of retinal nerve fibre layer measurement by RTVue OCT and GDx VCC
Explore Article BJO Online (Jul 28 2010)
Aim To evaluate the diagnostic performances and correlations of retinal nerve fibre layer (RNFL) thickness measured by RTVue OCT and GDx variable corneal compensation (VCC). Methods The total and regional RNFL thickness were measured by RTVue OCT and GDx VCC in 62 normal eyes and 72 glaucomatous eyes of Chinese subjects. The RNFL thickness profiles of normal and glaucomatous eyes by RTVue OCT are plotted. Correlations of RNFL thickness measured by RTVue OCT and GDx VCC were assessed using the Pearson correlation. The discriminating abilities of the two techniques for detection of glaucoma were compared by the area under the ...
Comment on Article Mentions: Optovue RTVue-100 Capital Medical University
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Variety, Variability and Veracity: Macular Thickness and Reproducibility Among Optical Coherence Tomography Systems
Explore Article American Journal of Ophthalmology (Jul 27 2010)
Spectral-domain optical coherence tomography (SD OCT) has had a profound impact on clinical and experimental ophthalmology, but also presented practicing eye specialists with the important and expensive decision of whether to invest in SD OCT technology. Unlike time-domain (TD) OCT, for which only one company had commercial propriety, there are several SD OCT systems currently available. Also, unlike other previous potential competitors of TD OCT, all SD OCT devices provide fast, high-resolution, retinal cross-sectional scans. Therefore, a method to differentiate these systems is desirable, especially in nonexperimental settings.
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Fundus Autofluorescence and Optical Coherence Tomographic Findings in Acute Zonal Occult Outer Retinopathy
Explore Article LWW Online (Jul 27 2010)
Purpose: The purpose of this study was to investigate the fundus autofluorescence and optical coherence tomography findings in eyes with acute zonal occult outer retinopathy (AZOOR). Methods: A retrospective observational case series of the fundus autofluorescence and spectral domain optical coherence tomography in a series of patients with AZOOR. Results: There were 19 eyes of 11 patients (10 women), who had a mean age of 49.1 +/- 13.9 years. Fundus autofluorescence abnormalities were seen in 17 of the 19 eyes, were more common in the peripapillary area, and were smaller in extent than the optical coherence tomography abnormalities. Nine eyes ...
Comment on Article Mentions: Richard F. Spaide
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Evaluation of bilateral minimum thickness of normal corneas based on Fourier-domain optical coherence tomography
Explore Article Journal of Cataract & Refractive Surgery (Jul 26 2010)
Purpose: To determine the normative ranges and various aspects of the relationship between the minimum corneal thicknesses (MCT) in fellow eyes and the location of the MCT in relation to the central cornea using Fourier-domain optical coherence tomography (OCT).Setting: Tertiary care ophthalmic hospital, Chennai, India.Methods: In this cross-sectional observational trial, both eyes of consecutive healthy young subjects with a low refractive error and no clinical or topographic evidence of corneal disorders had bilateral pachymetric assessment with a Fourier-domain OCT platform (RTVue). The MCT, central corneal thickness (CCT), and x–y coordinates of the MCT location were noted.Results: The CCT and MCT ...
Comment on Article Mentions: Optovue RTVue-100 Amar Agarwal Optovue
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In vivo functional retinal optical coherence tomography
Explore Article SPIE Digital Library (Jul 23 2010)
An experimental design for noninvasive assessment of neural retinal tissue function with enhanced sensitivity is presented. By matching the response detection to a defined flicker frequency stimulus similar to heterodyne detection, the response signal will be shifted out of the low-frequency noise and the specificity of response detection will be strongly enhanced. Optimal measurement parameters are discussed, such as the function and timing of the response function to a single flash stimulus. The results indicate responses on the order of 200 ms that have been probed with our frequency-encoded approach using 5 Hz flickering. Preliminary results indicate the feasibility of ...
Comment on Article Mentions: Medical University of Vienna Rainer A. Leitgeb
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Statistical Analysis of Retinal Tomographic Pseudo Images for Diagnostic Purpose
Explore Article SpringerLink Home (Jul 23 2010)
The majority of visual impairments are related to retinal disorders. Therefore, techniques useful for early detection of retinal anomalies are of great interest for diagnosis and treatment of related pathologies. Optical Coherence Tomography (OCT) is a non-invasive technique that is becoming increasingly important in the analysis of human retina. This technique produces sections of a three dimensional reflectance map, which are pseudo-images of the retinal structure. In these pseudo-images, early pathologies may produce local modifications of reflectance, which visually, appear as blots. Consequently, automatic procedures for detection of such blots may be of help in the diagnosis of many retinal ...
Comment on Article Mentions: University of Southern California David Huang Ou Tan
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High-Resolution Fourier-Domain Optical Coherence Tomography of Choroidal Neovascular Membranes Associated with Age-Related Macular Degeneration
Explore Article iovs.org (Jul 22 2010)
High-resolution Fourier-domain optical coherence tomography (Fd-OCT) provided visualization of choroidal neovascular membrane (CNVM) and associated morphologic changes in the retina in eyes with neovascular age-related macular degeneration. The growth pattern and size of CNVM was determined with Fd-OCT and correlated better with findings on fluorescein angiography in eyes with classic lesions.
Comment on Article Mentions: John S. Werner UC Davis Robert J. Zawadzki
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Macular Thickness Variations with Sex, Age, and Axial Length in Healthy Subjects: A Spectral Domain-Optical Coherence Tomography Study
Explore Article iovs.org (Jul 22 2010)
Purpose. To assess the relationship between macular retinal thickness and volume and age, sex, and refractive error/axial length with spectral domain–optical coherence tomography (SD-OCT). Methods. One randomly selected eye of 198 consecutive ophthalmically normal subjects (104 men, 94 women) between July 2008 and January 2009, with corrected visual acuities better than 20/30 were included in this cross-sectional study. Complete ophthalmic examination, axial length measurement with a laser interferometer, and macular cube 512 x 128 scan by SD-OCT were performed. Results. The mean age was 55.6 ± 16.4 years (range, 17–83), average refractive error was –2.17 ± 4.82 (range, –23.50–3.75), and ...
Comment on Article Mentions: Yonsei University Chan Yun Kim
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Tracking Progression with Spectral-Domain Optical Coherence Tomography in Geographic Atrophy Caused by Age-Related Macular Degeneration
Explore Article iovs.org (Jul 22 2010)
Purpose. To investigate, with the use of spectral-domain optical coherence tomography (SD-OCT), microstructural alterations over time in eyes with progressive geographic atrophy (GA) due to age-related macular degeneration. Methods. Forty-six eyes of 26 patients (median age, 77.9 years [interquartile range (IQR), 71.8–81.0]) with GA without evidence of active or previous neovascular disease at baseline were examined by simultaneous confocal scanning laser ophthalmoscopy (cSLO) and SD-OCT. Serial examinations with alignment of follow-up to baseline scans were performed over a median period of 12.2 months (IQR, 10.2–15.3). Longitudinal SD-OCT variations were evaluated, including quantification of retinal thickness (RT) change and lateral spread ...
Comment on Article Mentions: University of Oxford Frank G. Holz Ludwig Maximilians Universität München
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High-Res Imaging Expands Vision Research of Live Birds of Prey: Study Produces First-Time Images of Retinal Structure of Hawks and Owls
Explore Article Newswise (Jul 21 2010)
Bird observatories all over the world may benefit from a newly designed high-resolution imaging system used to study the retinal structure of live birds of prey. In a recently published Investigative Ophthalmology & Visual Science article, researchers reveal unprecedented three-dimensional information about the retina of four species of raptors -- two hawks and two owls -- using the non-invasive, powerful imaging tool.
Comment on Article Mentions: Shuliang Jiao Robert W. Knighton University of Miami
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Assessment of Retinal Nerve Fibre Layer by Optical Coherence Tomography in Uveitis Patients With Papilloedema
Explore Article ClinicalTrials.gov (Jul 21 2010)
Assessment of optic disc morphology can be difficult in patients with uveitis and papilloedema. Therefore different optical coherence tomography (OCT) and laser scanning techniques may help to detect damage to the retinal nerve fibre layer
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Retinal Nerve Fiber Layer Imaging with Spectral-Domain Optical Coherence Tomography: Analysis of the Retinal Nerve Fiber Layer Map for Glaucoma Detection
Explore Article OphSource (Jul 20 2010)
Objective To evaluate the diagnostic performance of the retinal nerve fiber layer (RNFL) thickness deviation map imaged by a spectral-domain optical coherence tomography (OCT; Cirrus HD-OCT, Carl Zeiss Meditec Inc, Dublin, CA) and compare its sensitivity and specificity for glaucoma detection with circumpapillary RNFL measurement derived from the standard 3.46 mm diameter circle scan. Design Prospective, cross-sectional study. Participants We included 102 normal subjects and 121 glaucoma patients. Methods One eye from each individual was imaged with Cirrus HD-OCT and Stratus OCT (Carl Zeiss Meditec Inc.). Glaucoma was defined based on the presence of visual field defects with the Humphrey ...
Comment on Article Mentions: Zeiss Stratus OCT The Chinese University of Hong Kong Carl Zeiss Meditec
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Highly reproducible swept-source, dispersion-encoded full-range biometry and imaging of the mouse eye
Explore Article SPIE Digital Library (Jul 20 2010)
We report a high-speed, dispersion-encoded, full-range (DEFR) swept-source optical coherence tomography system for in vivo ocular imaging and biometry of small animals. The fast DEFR algorithm removes the depth ambiguity, gives access to objects located at the zero delay position, and doubles the sampling depth to 2×5.0 mm (at −101 to −71 dB sensitivity) in a single scan using 2048 samples/depth scan 0.43 nm line width of a light source operating at 1056 nm with 70 nm tuning range. The acquisition speed (frames of 512 depth scans in 18.3 ms) permits precise on-line monitoring during positioning and provides cross-sectional views ...
Comment on Article Mentions: Medical University of Vienna Bernd M. Hofer Cardiff University
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Stabilized retinal imaging with adaptive optics
Explore Article uspto.gov (Jul 20 2010)
A system provides an optical image of an object. A first module tracks a reference feature of the object. A second module includes a source for an imaging beam, a scanning device to move the imaging beam along a portion of the object and a detection device receives a signal associated with an image of the portion of the object. The first module controls the position of the imaging beam relative to the reference feature to correct for the motion of the object. A third module detects a distortion of the object and compensates for the distortion.
Comment on Article Mentions: Daniel X. Hammer Physical Sciences Incorporated R. Daniel Ferguson
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Boston Micromachines Wins R&D 100 Award for Retinal Imaging Instrument
Explore Article Deformable mirror (Jul 19 2010)
Cambridge, Mass., July 15, 2010 – Boston Micromachines Corporation, a leading provider of MEMS-based deformable mirror (DM) products for adaptive optics systems, announced today that a collaboration with Lawrence Livermore National Laboratory, the University of California, Davis, and the Indiana University School of Optometry has received a 2010 R&D 100 award for the development of a MEMS-based Adaptive Optics Optical Coherence Tomography (AO-OCT) instrument. The AO-OCT permits ophthalmologists to see the eye’s retina at the individual cell level. The awards, determined by an independent judging panel and the editors of R&D Magazine, recognize the 100 most technologically significant products introduced ...
Comment on Article Mentions: Boston Micromachines Lawrence Livermore National Laboratory Indiana University
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