1. Articles in category: Ophthalmology

    577-600 of 6512 « 1 2 ... 22 23 24 25 26 27 28 ... 270 271 272 »
    1. Ophthalmic tomographic imager with corneo-retinal image analysis

      Ophthalmic tomographic imager with corneo-retinal image analysis

      An optical image measuring device 1 splits low-coherence light L0 into signal light LS and reference light LR, and splits an optical path of the reference light LR into two optical paths having different optical path lengths to split the reference light LR into two reference lights LRa, LRb. Furthermore, the optical image measuring device 1 makes the reference lights LRa, LRb interfere with the signal light LS propagated through an eye E, generates an interference light LC reflecting a morphology in each of two depth positions (fundus oculi Ef and cornea Ec) of an eye E, and detects the ...

      Read Full Article
    2. University of Pittsburgh Receives a 2014 NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      University of Pittsburgh Receives a 2014 NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      University of Pittsburgh Receives a 2014 NIH Grant for $726,299 for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. The program began in 2000 and ends in 2019. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness and visual morbidity. Because the disease causes irreversible damage to neural tissue it is of utmost importance to identify glaucoma and its progression at the earliest possible stages. Through advancements in the use of optical coherence tomography (OCT) and other technologies, the long-term goal of this research project is to precisely ...

      Read Full Article
    3. Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic/ Case Western Reserve University Receiver 2014 NIH Grant for $203,124 for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery. The principal investigator is Justis Ehlers. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Optical coherence tomography (OCT) has revolutionized the management of ophthalmic diseases with the precise anatomic information it provides with non-invasive imaging. The high-resolution cross-sectional tissue details make OCT a natural complement to ophthalmic surgery. Intraoperative OCT (iOCT) has the potential to provide real-time feedback to surgeons thus improving surgical care and outcomes. This research activity will ...

      Read Full Article
    4. Spectral-domain optical coherence tomography features preceding new-onset neovascular membrane formation

      Spectral-domain optical coherence tomography features preceding new-onset neovascular membrane formation

      Objective To determine the frequency and characteristic spectral-domain optical coherence tomography (SD-OCT) features preceding new-onset choroidal neovascularization (CNV) in the fellow eye of neovascular age-related macular degeneration (AMD) with SD-OCT. Design A prospective, observational study. Participants Sixty-eight fellow eyes of patients with unilateral CNV. Methods SD-OCT was performed at baseline and then monthly. The main outcome measure is the description of retinal morphology 1 month before new onset of neovascularization. Results During the 48-month observation period, new-onset CNV was observed in 27 fellow eyes. Several morphologic features characterized SD-OCT images ≥1 months before new onset of CNV. These included new ...

      Read Full Article
    5. OPTICAL COHERENCE TOMOGRAPHIC REFLECTIVITY OF CYSTOID SPACES IS RELATED TO RECURRENT DIABETIC MACULAR EDEMA AFTER TRIAMCINOLONE

      OPTICAL COHERENCE TOMOGRAPHIC REFLECTIVITY OF CYSTOID SPACES IS RELATED TO RECURRENT DIABETIC MACULAR EDEMA AFTER TRIAMCINOLONE

      Purpose: To determine the association between reflectivity levels in foveal cystoid spaces on optical coherence tomography images and the course of the logarithm of the minimum angle of resolution (logMAR) after triamcinolone acetonide treatment for diabetic macular edema. Methods: We retrospectively reviewed 58 consecutive eyes treated with an intravitreal or sub-Tenon's injection of triamcinolone acetonide for diabetic macular edema. The foveal cystoid spaces within central 1 mm were circumscribed, followed by measurement of optical coherence tomography reflectivity. The correlation between the reflectivity and visual outcome was investigated. Results: The optical coherence tomography reflectivity levels in foveal cystoid spaces increased ...

      Read Full Article
    6. SUPRACHOROIDAL LAYER AND SUPRACHOROIDAL SPACE DELINEATING THE OUTER MARGIN OF THE CHOROID IN SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

      SUPRACHOROIDAL LAYER AND SUPRACHOROIDAL SPACE DELINEATING THE OUTER MARGIN OF THE CHOROID IN SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To define the morphology of outer choroidal margins in swept-source optical coherence tomography. Methods: This is a prospective observational study of 180 eyes: 20 eyes of healthy volunteers, 20 eyes of myopic patients, and 20 eyes from each of the following groups: macular hole, lamellar macular hole, epiretinal membranes, drusen, dry age-related macular degeneration (AMD), neovascular AMD, and vitreomacular traction. A single 12-mm wide swept-source optical coherence tomography image for each of the examined eyes consisting of 1,024 A-scans has been created. The main outcome measure selected was to estimate the presence of suprachoroidal layer, as well as ...

      Read Full Article
    7. COMBINED HAMARTOMA OF THE RETINA AND RETINAL PIGMENT EPITHELIUM: Findings on Enhanced Depth Imaging Optical Coherence Tomography in Eight Eyes

      COMBINED HAMARTOMA OF THE RETINA AND RETINAL PIGMENT EPITHELIUM: Findings on Enhanced Depth Imaging Optical Coherence Tomography in Eight Eyes

      Purpose: To assess combined hamartoma of the retina and retinal pigment epithelium with enhanced depth imaging optical coherence tomography. Methods: Retrospective, observational cases series in eight eyes of eight patients, with comparison between affected and unaffected eyes regarding enhanced depth imaging optical coherence tomography features of tumor, fovea, and choroid. Results: The mean age at presentation was 7 years. The tumor was macular (n = 5) or extramacular (n = 3). Enhanced depth imaging optical coherence tomography revealed irregularities in inner retina (n = 8) and/or all retinal layers (n = 3), with epiretinal membrane (n = 8), causing an inner retinal sawtooth (mini-peak ...

      Read Full Article
    8. En-face high-penetration optical coherence tomography imaging in polypoidal choroidal vasculopathy

      En-face high-penetration optical coherence tomography imaging in polypoidal choroidal vasculopathy

      Aim To observe the choroidal microstructure in polypoidal choroidal vasculopathy (PCV) using high-penetration optical coherence tomography (HP-OCT) with a long-wavelength light source that visualises tissue beneath the retinal pigment epithelium (RPE) and deep choroid, and to compare the findings with those of indocyanine green angiography (ICGA). Methods In this retrospective, non-invasive, observational case series, 19 eyes (18 patients) with PCV were observed using HP-OCT (swept source, 100 000 A-scans/s, 1060 nm wavelength) and ICGA. The HP-OCT scan protocol was a 3×3-mm or 6×6-mm square containing 256×256 or 512×128 A-scans. The choroidal thickness (CT) was measured ...

      Read Full Article
    9. Optical Coherence Tomography–Defined Changes Preceding the Development of Drusen-Associated Atrophy in Age-Related Macular Degeneration

      Optical Coherence Tomography–Defined Changes Preceding the Development of Drusen-Associated Atrophy in Age-Related Macular Degeneration

      Purpose To characterize the pathological changes preceding the development of drusen-associated atrophy in eyes with age-related macular degeneration (AMD) using spectral-domain optical coherence tomography (SD-OCT). Design Longitudinal and cross-sectional retrospective observational study. Participants A total of 181 participants with intermediate AMD in at least 1 eye (141 unilateral, 40 bilateral) were assessed longitudinally. A total of 230 participants with bilateral intermediate AMD (40 longitudinal participants with an additional 190 participants) were analyzed cross-sectionally. Methods Spectral-domain OCT, color fundus photography (CFP), near-infrared reflectance, and fundus autofluorescence imaging were performed in all participants at cross-section and every 3 months for up to ...

      Read Full Article
    10. Optical coherence tomography in patients with a history of juvenile multiple sclerosis reveals early retinal damage

      Optical coherence tomography in patients with a history of juvenile multiple sclerosis reveals early retinal damage

      Background and purpose Some 3%−10% of patients with multiple sclerosis (MS) experience disease onset before the age of 18 years (‘early’ onset MS, EOMS). Optical coherence tomography is a non-invasive method to measure retinal nerve fibre layer thickness (RNFLT) and total macular volume (TMV) and may be useful to differentiate axonal and neuronal damage in the retina of patients with a history of EOMS. Here RNFLT and TMV in EOMS patients after a mean disease duration of 11.6 years were compared with patients with age- or disease-duration-matched later onset MS (LOMS) and healthy controls (HCs). Methods In this ...

      Read Full Article
    11. Fiber-based polarization-sensitive OCT of the human retina with correction of system polarization distortions

      Fiber-based polarization-sensitive OCT of the human retina with correction of system polarization distortions

      In polarization-sensitive optical coherence tomography (PS-OCT) the use of single-mode fibers causes unpredictable polarization distortions which can result in increased noise levels and erroneous changes in calculated polarization parameters. In the current paper this problem is addressed by a new Jones matrix analysis method that measures and corrects system polarization distortions as a function of wavenumber by spectral analysis of the sample surface polarization state and deeper located birefringent tissue structures. This method was implemented on a passive-component depth-multiplexed swept-source PS-OCT system at 1040 nm which was theoretically modeled using Jones matrix calculus. High-resolution B-scan images are presented of the ...

      Read Full Article
    12. SAVE: a grading protocol for clinically significant diabetic macular oedema based on optical coherence tomography and fluorescein angiography

      SAVE: a grading protocol for clinically significant diabetic macular oedema based on optical coherence tomography and fluorescein angiography

      Aim To analyse a new grading protocol for clinically significant diabetic macular oedema (CSME) based on spectral domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA). Methods 56 eyes of 40 patients with CSME were examined by Cirrus OCT (Carl Zeiss Meditec), Spectralis HRA and OCT (Heidelberg Engineering) on the same day. Three graders analysed images based on a newly developed grading protocol integrating all relevant information from OCT and FA. The protocol defined four categories: (1) subretinal fluid (category ‘S’); (2) the planimetrically measured oedematous area (category ‘A’); (3) vitreo-retinal interface abnormalities (category ‘V’); and (4) CSME aetiology (category ...

      Read Full Article
    13. Quantitative optical inspection of contact lenses immersed in wet cell using swept source OCT

      Quantitative optical inspection of contact lenses immersed in wet cell using swept source OCT

      We demonstrate swept source optical coherence tomography (OCT) imaging of contact lenses (CLs) in a wet cell and comprehensive quantitative characterization of CLs from volumetric OCT datasets. The approach is based on a technique developed for lens autopositioning and autoleveling enabled by lateral capillary interactions between the wet cell wall and the lens floating on the liquid surface. The demonstrated OCT imaging has enhanced contrast due to the application of a scattering medium and it improves visualization of both CL interfaces and edges. We also present precise and accurate three-dimensional metrology of soft and rigid CLs based on the OCT ...

      Read Full Article
    14. Microscopy without Slides: An Introduction to Optical Coherence Tomography (OCT)

      Microscopy without Slides: An Introduction to Optical Coherence Tomography (OCT)

      Optical coherence tomography (OCT) is one of several exciting, advanced imaging techniques that are beginning to appear in pathology. OCT can rapidly generate photomicrograph-like images directly from tissue, without the need for glass slide histology. Because the images resemble low-to-medium magnification microscope images, pathologists should be able to adapt their existing diagnostic expertise to these novel images. Both in-vivo and specimen (ex-vivo) applications are possible; this means that advanced imaging may permit pathologists to make diagnoses directly on patient images. Advanced imaging therefore represents a fabulous opportunity for pathologists in the 21st century. This talk will focus on specimen OCT ...

      Read Full Article
    15. Seasonal pricing scheme to help independents introduce OCT

      Seasonal pricing scheme to help independents introduce OCT

      Heidelberg Engineering has introduced a seasonal pricing scheme to facilitate the introduction of the company’s Spectralis OCT. The rental scheme is reduced to £300 per month, for the first three months, with entrance to the scheme closing at the end of this month (August 31). The cost gradually rises in line with the practice’s ability to maximise use of the technology, as the professional team learns to promote and interpret the value of OCT on the High Street. Regional business manager, Tosh Vadhia, said: “This is a gentle way to ease into OCT. This opportunity enables OCT to ...

      Read Full Article
    16. Image processing apparatus and method

      Image processing apparatus and method

      An image processing apparatus for supporting imaging diagnosis of an eye is provided. A layer boundary of a retina region is detected from a tomographic image. A position where the detected layer boundary intersects with an upper or lower limit position of the image in the depth direction of the tomographic image is determined as a dividing position. The tomographic image is divided at the determined dividing position by a scan line in the depth direction of the tomographic image. Subsequently, whether the detection is a false detection is judged for each divided region. An average density value of the ...

      Read Full Article
    17. Compact, affordable optical test, measurement or imaging device

      Compact, affordable optical test, measurement or imaging device

      The system disclosed is for optical coherence tomography (OCT). The system includes an improved interferometric system for metrology, detection, ranging as well as imaging system based on optical coherence tomography (OCT). Further, the method provides advancements in detection, imaging of samples in biological, medical, ophthalmic, corneal and retinal diagnosis.

      Read Full Article
    18. Optical coherence tomographic imaging device and imaging method of optical coherence tomographic image

      Optical coherence tomographic imaging device and imaging method of optical coherence tomographic image

      An optical tomographic imaging device and the like which suppress influence in the case of a measuring beam being truncated by an iris, and can ensure reliability of a tomographic image which is acquired, when imaging the tomographic image of a retina in an eyeground of an examined eye. An optical tomographic imaging device is configured to have an observation unit observing a state of irradiating an examined object with the measuring beam, and imaging a state of the measuring beam being incident on the examined object as an observation image, a recording unit recording the observation image by linking ...

      Read Full Article
    19. Imaging apparatus and method for taking image of eyeground by optical coherence tomography

      Imaging apparatus and method for taking image of eyeground by optical coherence tomography

      An optical unit concentrates light beams from measurement-light paths at first and second irradiation positions on an eyeground. Next, a control unit controls a scanning unit so that the light beams concentrated at the first and second irradiation positions are scanned in first and second scanning areas of the eyeground and so that the first and second scanning areas overlap to form an overlap area. A tomographic-information acquisition unit acquires first tomographic information and second tomographic information in the first and second scanning areas from interference light. Third tomographic information is acquired from the first tomographic information and the second ...

      Read Full Article
    20. Ganglion Cell-Inner Plexiform Layer Thickness of High Definition Optical Coherence Tomography in Perimetric and Preperimetric Glaucoma

      Ganglion Cell-Inner Plexiform Layer Thickness of High Definition Optical Coherence Tomography in Perimetric and Preperimetric Glaucoma

      Purpose. We determined the diagnostic performance of ganglion cell-inner plexiform layer (GCIPL) parameters of high definition optical coherence tomography (HD-OCT) in perimetric and preperimetric glaucoma, and compared it to optic nerve head (ONH) and peripapillary retinal nerve fiber layer (RNFL) parameters. Methods. In a cross-sectional study, 53 eyes of normal subjects and 83 eyes of glaucoma patients (62 perimetric and 21 preperimetric) from the Longitudinal Glaucoma Evaluation Study (LOGES) underwent HD-OCT imaging with Optic Disc and Macular Cube protocols. Diagnostic abilities of GCIPL, ONH, and RNFL parameters were determined using area under receiver operating characteristic curves (AUC) and likelihood ratios ...

      Read Full Article
    21. Evaluation of iris and iridociliary body lesions with anterior segment optical coherence tomography versus ultrasound B-scan

      Evaluation of iris and iridociliary body lesions with anterior segment optical coherence tomography versus ultrasound B-scan

      AIMS: To compare anterior segment optical coherence tomography (AS-OCT) with ultrasound B-scan (USB) in evaluating iris and iridociliary body lesions. METHODS: Image features and resolution comparison between AS-OCT and USB in 126 patients (126 eyes) presenting with iris or iridociliary body lesion. Bland-Altman plots were generated to assess the level of agreement between the two techniques. RESULTS: The three most common diagnoses were iris naevi (62 (49.2%)), iris pigment epithelial cysts (23 (18.3%)) and iris melanoma (11 (8.7%)). Image feature comparison for USB was better than AS-OCT in visualising all tumour margins (81 (64.3%) vs 59 ...

      Read Full Article
    22. The effect of myopic optic disc tilt on measurement of spectral-domain optical coherence tomography parameters

      The effect of myopic optic disc tilt on measurement of spectral-domain optical coherence tomography parameters

      Background To compare the spectral-domain optical coherence tomography (SD-OCT) parameters, including ganglion cell-inner plexiform layer (GCIPL) thickness, retinal nerve fibre layer (RNFL) thickness and optic nerve head (ONH) parameters between glaucomatous eyes with myopic tilted optic disc and non-tilted optic disc, and to investigate the effect of optic disc tilt on the diagnostic performance of these parameters. Methods The study included 82 patients with glaucoma and 41 refraction-matched normal subjects. The OCT parameters and their diagnostic abilities were compared between the non-tilted disc group (N=41) and tilted disc group (N=41). Results The ONH parameters in the tilted disc ...

      Read Full Article
    23. Optical Coherence Tomography - Glaucoma Relevant Examinations

      Optical Coherence Tomography - Glaucoma Relevant Examinations

      This video demonstrates the use of Optical Coherence Tomography (OCT) in Glaucoma screening and management. In under 90 seconds we are able to capture a full battery of examinations. In order: (1) Macular Cube (enables Ganglion Cell Cell layer analysis) (2) Optic Nerve Head Cube (Enables ONH & RNFL analysis) (3) Anterior OCT - Iridocorneal Angle Temporal Eye (4) Anterior OCT - Iridocorneal Angle (Nasal Eye) (5) HD Raster - Through optic nerve and macula The Zeiss Cirrus 5000 HD-OCT was used in the making of this video

      Read Full Article
    24. Optical Coherence Tomography to Evaluate Dengue

      Optical Coherence Tomography to Evaluate Dengue

      The recent report you published on the use of optical coherence tomography (OCT) to evaluate dengue was very interesting [ 1 ]. Rhee and Han [ 1 ] concluded that "Follow-up examination of individuals with dengue fever and associated visual impairment should involve the use of OCT to evaluate visual acuity and visual field change." In fact, the ocular complications of dengue are typically overlooked, as a proper examination is rarely performed. As Mendes et al. [ 2 ] noted, "Dengue fever can lead to visual impairment detectable by ophthalmological exams such as angiography, retinography, and OCT imaging, as well as retinal and cortical electrophysiology." Severe ...

      Read Full Article
    577-600 of 6512 « 1 2 ... 22 23 24 25 26 27 28 ... 270 271 272 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (5 articles) UCLA
    2. (5 articles) University of Miami
    3. (4 articles) Oregon Health & Science University
    4. (3 articles) University of Houston
    5. (3 articles) Center for Ophthalmic Optics and Lasers
    6. (3 articles) University of Southern California
    7. (3 articles) Fudan University
    8. (3 articles) National Institutes of Health
    9. (2 articles) Johns Hopkins University
    10. (2 articles) Thomas Jefferson University
    11. (2 articles) Seoul National University
    12. (2 articles) Singapore Eye Research Institute
  4. People in the News

    1. (5 articles) Srinivas R. Sadda
    2. (5 articles) David Huang
    3. (3 articles) Philip J. Rosenfeld
    4. (3 articles) Richard F. Spaide
    5. (3 articles) James G. Fujimoto
    6. (3 articles) Ruikang K. Wang
    7. (3 articles) Bruno Lumbroso
    8. (2 articles) K. Bailey Freund
    9. (2 articles) Jay S. Duker
    10. (2 articles) Jiasong Li
    11. (2 articles) Kirill V. Larin
    12. (2 articles) Marco Rispoli
  5. OCT Companies in the News

    1. (8 articles) Optovue
    2. (7 articles) Carl Zeiss Meditec
    3. (4 articles) Heidelberg Engineering
    4. (2 articles) Topcon Medical Systems
    5. (2 articles) Haag-Streit
    6. (2 articles) Optos
    7. (1 articles) OptiScan
    8. (1 articles) Praevium Research
    9. (1 articles) Tomey Corporation
    10. (1 articles) Thorlabs
    11. (1 articles) Voxeleron
    12. (1 articles) Bioptigen
  6. OCT Products in the News

    1. (7 articles) Heidelberg Spectralis
    2. (5 articles) Zeiss Cirrus HD-OCT
    3. (4 articles) Optovue RTVue-100
    4. (2 articles) Zeiss Stratus OCT
    5. (2 articles) Optovue iVue
    6. (1 articles) Topcon DRI OCT-1 Atlantis
    7. (1 articles) Ophthalmic Technologies Spectral OCT/SLO
    8. (1 articles) Tomey SS-1000 CASIA