1. Articles in category: Ophthalmology

    577-600 of 7999 « 1 2 ... 22 23 24 25 26 27 28 ... 332 333 334 »
    1. Inflatable medical interfaces and other medical devices, systems, and methods

      Inflatable medical interfaces and other medical devices, systems, and methods

      An inflatable mask with two ocular cavities can seal against a user's face by forming an air-tight seal around the periphery of the user's eye socket. The sealed air-tight ocular cavity can be pressurized to take ocular measurements. The mask can conform to the contours of a user's face by inflating or deflating the mask. In addition, the distance between the user and a medical device (e.g. an optical coherence tomography instrument) can be adjusted by inflating or deflating the mask. Also disclosed herein is an electronic encounter portal and an automated eye examination. Other embodiments ...

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    2. Systems and methods for automated classification of abnormalities in optical coherence tomography images of the eye

      Systems and methods for automated classification of abnormalities in optical coherence tomography images of the eye

      Systems and methods for classifying abnormalities within optical coherence tomography images of the eye are presented. One embodiment of the present invention is the classification of pigment epithelial detachments (PEDs) based on characteristics of their internal reflectivity, size and shape. The classification can be based on selected subsets of the data located within or surrounding the abnormalities. Training data can be used to generate the classification scheme and the classification can be weighted to highlight specific classes of particular clinical interest.

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    3. Method for monitoring image of examinee's eye and monitoring system

      Method for monitoring image of examinee's eye and monitoring system

      A method for monitoring an image of an examinee's eye includes: obtaining first image data including a first examinee's eye image captured by a first ophthalmologic photographing apparatus, and additional information including type information on the first examinee's eye image; obtaining second image data including a second examinee's eye image captured by a second ophthalmologic photographing apparatus different from the first ophthalmologic photographing apparatus, and additional information including type information on the second examinee's eye image; recognizing the first examinee's eye image and the second examinee's eye image as the same type of ...

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      Mentions: Nidek
    4. Feasibility of Spectral Domain Optical Coherence Tomography Acquisition Using a Handheld Versus Conventional Tabletop Unit

      Feasibility of Spectral Domain Optical Coherence Tomography Acquisition Using a Handheld Versus Conventional Tabletop Unit

      Purpose: Patients afflicted with ocular complications of diabetes represent a diverse demographic who often cannot undergo spectral-domain optical coherence tomography (SD-OCT) imaging of the retina due to postural restraints. Our pilot study compared imaging acquisition methods using SD-OCT in the handheld (HH) mode versus the conventional tabletop (TT) method. Methods: Our study included 22 undilated eyes of 22 subjects (mean ± SD age, 35.8 ± 16.8 years) imaged using HH and TT iVue SD-OCT (Optovue, Fremont, CA). Statistical analysis was performed using Microsoft Excel 12.2.7 (Microsoft Corporation, Redmond, WA) software with an accepted significance of P < .05. Results ...

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    5. Comparison of Prevalence of Diabetic Macular Edema Based on Monocular Fundus Photography vs Optical Coherence Tomography

      Comparison of Prevalence of Diabetic Macular Edema Based on Monocular Fundus Photography vs Optical Coherence Tomography

      Importance Diagnosing diabetic macular edema (DME) from monocular fundus photography vs optical coherence tomography (OCT) central subfield thickness (CST) can yield different prevalence rates for DME. Epidemiologic studies and telemedicine screening typically use monocular fundus photography, while treatment of DME uses OCT CST. Objective To compare DME prevalence from monocular fundus photography and OCT. Design, Setting, and Participants Retrospective cross-sectional study of DME grading based on monocular fundus photographs and OCT images obtained from patients with diabetic retinopathy at a single visit between July 1, 2011, and June 30, 2014, at a university-based practice and analyzed between July 30, 2014 ...

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    6. Semi-automated quantification of retinal IS/OS damage in en-face OCT image

      Semi-automated quantification of retinal IS/OS damage in en-face OCT image

      A variety of vision ailments are indicated by structural changes in the retinal substructures of the posterior segment of the eye. In particular, integrity of the inner-segment/outer-segment (IS/OS) junction directly relates to the visual acuity. In the en-face optical coherence tomography (OCT) image, IS/OS damage manifests as a dark spot in the foveal region, and its quantification, usually performed by experts, assumes diagnostic significance. In this context, in view of the general scarcity of experts, it becomes imperative to develop algorithmic methods to reduce expert time and effort. Accordingly, we propose a semi-automated method based on level ...

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    7. En Face Optical Coherence Tomography to Detect and Measure Geographic Atrophy

      En Face Optical Coherence Tomography to Detect and Measure Geographic Atrophy

      Purpose : To detect and quantify geographic atrophy (GA) secondary to age-related macular degeneration using en face optical coherence tomography (OCT) and to correlate it to GA measured with fundus autofluorescence (FAF). Methods : Twenty-four consecutive patients (27 eyes) were studied with both standard (STD)- and enhanced depth imaging (EDI)-OCT. En face OCT images were obtained at the outer retinal layer (OR) and at the choroidal layer (CH) level for both STD- and EDI-OCT. Areas of GA were measured on the en face OCT images and were correlated with the GA areas measured on blue (B)- and near infrared (NIR)-wavelength ...

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    8. Macular microangiopathy in sickle cell disease using optical coherence tomography angiography

      Macular microangiopathy in sickle cell disease using optical coherence tomography angiography

      Purpose To characterize the optical coherence tomography angiography (OCTA) appearance of the perifoveal macular microvasculature in visually asymptomatic patients with sickle cell disease, and to compare these findings with those of fluorescein angiography (FA). Design Retrospective observational case series. Methods Eighteen eyes of 9 consecutive patients with a median age of 41 years (range: 19-54) with electrophoretic confirmation of sickle cell disease were included and analyzed. A complete ophthalmologic examination was performed, including fundus examination, FA (Spectralis HRA+OCT, Heidelberg Engineering, Heidelberg, Germany), and OCTA (RTVue XR Avanti, Optovue Inc, Fremont, California, USA). Nine eyes of five healthy subjects were ...

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    9. OCT-based crystalline lens topography in accommodating eyes

      OCT-based crystalline lens topography in accommodating eyes

      ustom Spectral Domain Optical Coherence Tomography (SD-OCT) provided with automatic quantification and distortion correction algorithms was used to measure anterior and posterior crystalline lens surface elevation in accommodating eyes and to evaluate relationships between anterior segment surfaces. Nine young eyes were measured at different accommodative demands. Anterior and posterior lens radii of curvature decreased at a rate of 0.78 ± 0.18 and 0.13 ± 0.07 mm/D, anterior chamber depth decreased at 0.04 ± 0.01 mm/D and lens thickness increased at 0.04 ± 0.01 mm/D with accommodation. Three-dimensional surface elevations were estimated by subtracting ...

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    10. Re: McNabb et al.: Optical coherence tomography accurately measures corneal power change from laser refractive surgery (Ophthalmology 2015;122:677-86)

      Re: McNabb et al.: Optical coherence tomography accurately measures corneal power change from laser refractive surgery (Ophthalmology 2015;122:677-86)

      I read with interest the article by McNabb et al 1 regarding the measurement of corneal power in eyes that have undergone refractive surgery. One of the study's limitations was that myopic and hyperopic eyes were analyzed in a single group. It is known that after refractive surgery there is an overestimation of the corneal power in the eyes that had surgery for myopia, 2,3 and there is an underestimation of the power of the cornea in eyes that had surgery for hyperopia. 4 Evaluating the overall differences in corneal power for both refractive defects may introduce bias ...

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    11. Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula

      Optical Coherence Tomography Follow-up of an Unusual Case of Old Rhegmatogenous Retinal Detachment With a Hemorrhagic Macrocyst at the Macula

      A 32-year-old female presented with visual acuity of hand movement close to face, an old inferior rhegmatogenous retinal detachment (RRD), and a large hemorrhagic macular macrocyst (HMM) in the right eye. After 2 weeks of successful vitreoretinal surgery, the HMM started decreasing in height and resolved by 3 months. On optical coherence tomography, a zone of hyperreflectivity in the outer retinal layers was evident on resolution of the cyst. At final follow-up, the visual acuity improved to 1/60 only. Though HMM resolved completely after retinal reattachment, alteration and thickening of microarchitecture of the outer retinal layers ensued.

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    12. Ophthalmic photographing apparatus and storage medium storing ophthalmic photographing program

      Ophthalmic photographing apparatus and storage medium storing ophthalmic photographing program

      An ophthalmic photographing apparatus includes: an interference optical system configured to acquire a tomographic image of an eye; a processor; and memory storing computer readable instructions, when executed by the processor, causing the ophthalmic photographing apparatus to: control the interference optical system to acquire multiple tomographic images, and store the multiple tomographic images in a storage unit; acquire a composite image based on the multiple tomographic images stored in the storage unit; start a photographing operation for acquiring the multiple tomographic images based on the photographing position; acquire the composite image from the multiple tomographic images which are acquired by ...

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      Mentions: Nidek
    13. Ocular modeling methods and apparatus

      Ocular modeling methods and apparatus

      A method and apparatus for modeling a lens of an eye, comprising: measuring the anterior shape of the eye's cornea; determining direct optical measurements of at least one parameter of the cornea and at least one parameter of the lens; determining the refractive index of the cornea; correcting the optical measurements to account for the effect of the refractive index of the cornea on the direct optical measurements; measuring the aberration of the eye; calculating the refractive index of the lens by combining the corrected measurements and the measured aberration; and further correcting the optical measurements of the lens ...

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    14. Prevalence Of Reticular Pseudodrusen In AGE-RELATED Macular Degeneration Using Multimodal Imaging

      Prevalence Of Reticular Pseudodrusen In AGE-RELATED Macular Degeneration Using Multimodal Imaging

      Purpose: To determine the rate of reticular pseudodrusen (RPD) in age-related macular degeneration using multimodal imaging, including color fundus photography, the blue channel image of fundus photography, infrared reflectance, fundus autofluorescence, multicolor imaging, and spectral domain optical coherence tomography, as well as to compare the sensitivities and specificities of these modalities for detecting RPD. Methods: This prospective study included 243 eyes from 125 consecutive patients with age-related macular degeneration. They underwent fundus examination including color fundus photography, blue channel, infrared reflectance, fundus autofluorescence, multicolor imaging, and spectral domain optical coherence tomography in both eyes. To be considered as having RPD ...

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    15. Expanded Clinical Spectrum Of Multiple Evanescent White Dot Syndrome With Multimodal Imaging

      Expanded Clinical Spectrum Of Multiple Evanescent White Dot Syndrome With Multimodal Imaging

      Purpose: To evaluate and characterize multiple evanescent white dot syndrome abnormalities with modern multimodal imaging modalities. Methods: This retrospective cohort study evaluated fundus photography, fluorescein angiography, indocyanine green angiography, optical coherence tomography, enhanced depth imaging optical coherence tomography, short-wavelength autofluorescence, and near-infrared autofluorescence.

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    16. HIGH-RESOLUTION Multimodal Imaging After Idiopathic Epiretinal Membrane Surgery

      HIGH-RESOLUTION Multimodal Imaging After Idiopathic Epiretinal Membrane Surgery

      Purpose: To investigate the changes of the vitreomacular interface during a 1-year follow-up after idiopathic epiretinal membrane (iERM) surgery. Methods: Six patients affected by fovea-attached iERM were recruited in this pilot study. Pars plana vitrectomy associated with epiretinal membrane peeling was performed uneventfully in all cases. In four cases, the inner limiting membrane was removed using Brilliant blue G. En face high-resolution adaptive optics and cross-sectional spectral domain optical coherence tomography retinal imaging were performed before and at 1, 3, 6, and 12 months after surgery. The microstructures of vitreomacular interface in high-resolution adaptive optics images were correlated to the ...

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    17. Optical Coherence Tomographic Comparison of Cuban Epidemic and Leber’s Hereditary Optic Neuropathy

      Optical Coherence Tomographic Comparison of Cuban Epidemic and Leber’s Hereditary Optic Neuropathy

      Following the epidemic of optic and peripheral neuropathy, which occurred in Cuba between 1991 and 1993, a number of patients have been re-evaluated, including testing with optical coherence tomography (OCT) and electrophysiology. At the same time, a number of patients with Leber’s hereditary optic neuropathy have also been evaluated. The purpose of this study was to detect residual loss of retinal nerve fibre layer (RNFL) in patients who suffered Cuban epidemic optic neuropathy (CEON), and to compare these findings with those in patients with Leber’s hereditary optic neuropathy (LHON). Optical coherence tomography as well as clinical examinations were ...

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      Mentions: Tufts University
    18. Optical coherence tomography and electrophysiology of retinal and visual pathways in Wilson’s disease

      Optical coherence tomography and electrophysiology of retinal and visual pathways in Wilson’s disease

      We evaluated correlations between positive findings of changes on brain magnetic resonance imaging (MRI) and selected morphological and electrophysiological parameters of the retinal and visual systems in Wilson’s disease. Fifty-eight Wilson’s disease symptomatic patients were divided according to whether they displayed brain changes on MRI (positive, n = 39; negative, n = 19). All participants and healthy control group ( n = 30), underwent retinal optical coherence tomography to assess the thickness of macula and the total retinal nerve fiber layer. Visual evoked potentials were measured and electroretinography was performed. Macular and retinal nerve fibers were thinner in participants with changes on ...

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    19. Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification

      Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification

      We present 2 cases of anterior chamber ointment with evidence of progressive endothelial cell loss. In both cases, an anterior segment optical coherence tomography (OCT) was similar to an OCT of a tobramycin-dexamethasone ointment placed on a pen tip. An anterior segment OCT also demonstrated the direct contact of the globule with the corneal endothelium. A gas chromatography/mass spectrometry analysis documented the similarity to tobramycin-dexamethasone ointment in 1 case. Anterior segment OCT can help in confirming the diagnosis. Corneal endothelial injury is a continuous process, and its clinical manifestation is related to the size of the globule, the initial ...

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    20. Normal Macular Thickness in Healthy Indian Eyes Using Spectral Domain Optical Coherence Tomography

      Normal Macular Thickness in Healthy Indian Eyes Using Spectral Domain Optical Coherence Tomography

      Purpose: To determine macular thickness and its variation with age and sex in healthy Indian eyes using Zeiss spectral domain optical coherence tomography (SD-OCT). Design: A prospective, cross-sectional study. Methods: Four hundred healthy adult subjects (>=18 years) underwent macular cube scanning using Zeiss SD-OCT. Macular thickness from all 9 regions of the Early Treatment Diabetic Retinopathy Study map was documented for each subject. Variations in macular thickness by age and sex were determined. Results: The mean age of the subjects was 38.05 +/- 12.13 (range, 18-78) years. The mean ages in men and women were 39.19 +/- 12.16 ...

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    21. Multimodal imaging findings in a case of severe Central Serous Chorioretinopathy in an uncomplicated pregnancy

      Multimodal imaging findings in a case of severe Central Serous Chorioretinopathy in an uncomplicated pregnancy

      Background Central Serous Chorioretinopathy (CSC) has been previously reported as an infrequent complication of pregnancy that usually resolves spontaneously after delivery, with minimal or no sequel. We report a case of a severe form of CSC in an uncomplicated pregnancy with extensive subfoveal exudates and severe permanent visual loss. Multimodal imaging techniques, including color and red-free photographs, near-infrared reflectance, fluorescein angiography, and spectral-domain optical coherence tomography, were performed and the findings were correlated to the changes in visual acuity. Case presentation A 35-year-old pregnant woman presented with loss of vision and metamorphopsia in her left eye. Fundus examination showed subfoveal ...

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    22. SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY DOCUMENTATION OF MACULAR PSEUDOHOLE EVOLUTION AND SPONTANEOUS RESOLUTION

      SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY DOCUMENTATION OF MACULAR PSEUDOHOLE EVOLUTION AND SPONTANEOUS RESOLUTION

      Purpose: To describe the natural history, optical coherence tomography characteristics, and proposed biomechanics of macular pseudohole (MPH) evolution and spontaneous resolution. Methods: Clinical case report, with longitudinal follow-up documented by fundus photographs and spectral domain optical coherence tomography. Results: A 26-year-old woman presented with visual disturbance secondary to an idiopathic epiretinal membrane. Subsequent formation of an MPH was observed. Spontaneous peeling of the epiretinal membrane occurred in conjunction with posterior vitreous detachment 6.5 years after initial presentation. The MPH resolved, and the patient's vision improved. Conclusion: Spontaneous epiretinal membrane peeling represents a potential mechanism for visual and anatomical ...

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    23. Automated segmentation of optic disc in SD-OCT images and cup-to-disc ratios quantification by patch searching-based neural canal opening detection

      Automated segmentation of optic disc in SD-OCT images and cup-to-disc ratios quantification by patch searching-based neural canal opening detection

      Glaucoma is one of the most common causes of blindness worldwide. Early detection of glaucoma is traditionally based on assessment of the cup-to-disc (C/D) ratio, an important indicator of structural changes to the optic nerve head. Here, we present an automated optic disc segmentation algorithm in 3-D spectral domain optical coherence tomography (SD-OCT) volumes to quantify this ratio. The proposed algorithm utilizes a two-stage strategy. First, it detects the neural canal opening (NCO) by finding the points with maximum curvature on the retinal pigment epithelium (RPE) boundary with a spatial correlation smoothness constraint on consecutive B-scans, and it approximately ...

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    24. BASELINE SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHIC HYPERREFLECTIVE FOCI AS A PREDICTOR OF VISUAL OUTCOME AND RECURRENCE FOR CENTRAL SEROUS CHORIORETINOPATHY

      BASELINE SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHIC HYPERREFLECTIVE FOCI AS A PREDICTOR OF VISUAL OUTCOME AND RECURRENCE FOR CENTRAL SEROUS CHORIORETINOPATHY

      Purpose: To investigate the association between baseline retinal microstructures including hyperreflective foci (HF), shown by spectral domain optical coherence tomography, and visual outcome and recurrence after laser photocoagulation for central serous chorioretinopathy. Methods: We retrospectively reviewed 62 eyes from the medical records of 62 central serous chorioretinopathy patients. At the initial visit, baseline visual acuity, presence of photoreceptor granulation, subretinal fluid thickness, choroidal thickness at the macula, and retinal pigment epithelium status at the leakage site were examined. In addition, the numbers of HF at the macula and the leakage site were counted at the inner, outer, subretinal, and sub-retinal ...

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