1. Articles in category: Ophthalmology

    577-600 of 6967 « 1 2 ... 22 23 24 25 26 27 28 ... 289 290 291 »
    1. OPTICAL COHERENCE TOMOGRAPHY-BASED POSITIONING REGIMEN FOR MACULAR HOLE SURGERY

      OPTICAL COHERENCE TOMOGRAPHY-BASED POSITIONING REGIMEN FOR MACULAR HOLE SURGERY

      Purpose: To evaluate an optical coherence tomography (OCT)-based positioning regimen for patients undergoing macular hole surgery. Method: We reviewed the medical records of all patients in our practice who underwent macular hole repair, instituting a modified OCT-based positioning regimen from November 1, 2011 through July 31, 2013. The regimen consisted of prone positioning at the conclusion of surgery with daily OCT imaging until the hole was confirmed closed at which point positioning was halted. Clinical data that were collected and recorded included visual acuities, stage of hole, size of hole, chronicity, preoperative and postoperative OCT imaging, and length of ...

      Read Full Article
    2. Comparison between the measurements of different parameters obtained from optic nerve head analysis by using Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT)

      Comparison between the measurements of different parameters obtained from optic nerve head analysis by using Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT)

      Purpose: A cross-sectional prospective nonrandomized study was undertaken to find out whether Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT) could be used interchangeably for the measurement of different parameters of optic nerve head in clinical practice. Materials and Methods: Measurements of disc area, cup area, rim area and cup-disc area ratio were obtained with the HRT3 and Stratus OCT printouts in 18 patients aged 20 to 70 years. True agreements between methods in measuring disc area, cup area, rim area and cup-disc area ratio were assessed using Bland-Altman statistical analysis. Eighteen patients with a mean age of ...

      Read Full Article
    3. Electroretinographic and optical coherence tomography findings in breast cancer patients using aromatase inhibitors

      Electroretinographic and optical coherence tomography findings in breast cancer patients using aromatase inhibitors

      Background : The present cross-sectional study has the purpose to investigate the impact of aromatase inhibitors (AIs) on retinal nerve fiber layer (RNFL) thickness, optic nerve and macular function in patients using AIs for breast cancer treatment. Methods : Participants in our study were 41 hormone-receptor-positive earlystage breast cancer patients who were treated with AIs in the adjuvant setting. Moreover, 40 age- and gender-matched control subjects, having neither ocular nor systemic disorders, were included in this study. All participants underwent a complete ophthalmological examination, including best corrected visual acuity (BCVA) assessment, RNFL thickness and central foveal thickness (CFT) measurement, visual evoked potentials ...

      Read Full Article
    4. The effect of rebreathing and hyperventilation on retinal and choroidal vessels measured by spectral domain optical coherence tomography Read More: http://informahealthcare.com/doi/abs/10.3109/15569527.2014.990154

      The effect of rebreathing and hyperventilation on retinal and choroidal vessels measured by spectral domain optical coherence tomography   Read More: http://informahealthcare.com/doi/abs/10.3109/15569527.2014.990154

      Objective : The purpose of this study was to examine the vasoreactivity in retina and choroid of the healthy eyes in response to experimentally altered partial arterial pressure of carbon dioxide (PaCO 2 ) using a non-invasive technique, spectral domain optical coherence tomography (SD-OCT). Materials and methods : The study included non-smoking participants between 18 and 35 years of age, having visual acuity of 20/20 and with no systemic and ocular diseases. At baseline, the participants breathed room air (normocapnia). Hypocapnia was created with the help of hyperventilation; for this, the participants were instructed to draw deep and quick breaths, resulting one ...

      Read Full Article
    5. Bausch + Lomb Introduces New Software and Advanced OCT Imaging System for VICTUS® Femtosecond Laser Platform

      Bausch + Lomb Introduces New Software and Advanced OCT Imaging System for VICTUS® Femtosecond Laser Platform

      Valeant Pharmaceuticals International, Inc. (NYSE: VRX and TSX: VRX) today announced that its wholly owned subsidiary, Bausch + Lomb, has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for an advanced Swept Source OCT (Optical Coherence Tomography) imaging system and updated software for its VICTUS ® Femtosecond Laser Platform that will provide surgeons with a new, redesigned interface. The intuitive interface is designed to allow faster, simpler customized treatment planning to help surgeons improve efficiency and patient-flow during surgical procedures. "With the availability of the advanced OCT imaging and software enhancements, surgeons can monitor treatments in real-time ...

      Read Full Article
    6. Optical Coherence Tomography: Detecting Disease Early Through Retinal Imaging

      Optical Coherence Tomography: Detecting Disease Early Through Retinal Imaging

      Early diagnosis of individuals with chronic disease is a global health goal because the sooner a physician can detect a disease in a patient, the better the prognosis. In the U.S. alone, more than 6 million people have diabetes without knowing it, according to a 2009 study. That study estimated the cost of undiagnosed type-2 diabetes in medical services and lost productivity to be $18 billion a year. Eye researchers have observed that many chronic diseases, such as diabetes, hypertension, and cardiovascular and cerebrovascular conditions, leave telltale clues of their presence in the retina. By detecting these clues using ...

      Read Full Article
    7. Landmark Detection for Fusion of Fundus and MRI Toward a Patient-Specific Multimodal Eye Model

      Landmark Detection for Fusion of Fundus and MRI Toward a Patient-Specific Multimodal Eye Model

      Ophthalmologists typically acquire different image modalities to diagnose eye pathologies. They comprise, e.g., Fundus photography, optical coherence tomography, computed tomography, and magnetic resonance imaging (MRI). Yet, these images are often complementary and do express the same pathologies in a different way. Some pathologies are only visible in a particular modality. Thus, it is beneficial for the ophthalmologist to have these modalities fused into a single patient-specific model. The goal of this paper is a fusion of Fundus photography with segmented MRI volumes. This adds information to MRI that was not visible before like vessels and the macula. This paper ...

      Read Full Article
    8. Monitoring Cerebral Hemodynamics Following Optogenetic Stimulation via Optical Coherence Tomography

      Monitoring Cerebral Hemodynamics Following Optogenetic Stimulation via Optical Coherence Tomography

      In this article, spectral domain optical coherence tomography is used to measure the hemodynamic response induced by optogenetic stimulation in the somatosensory cortex of transgenic mice. By analyzing the 3-D angiograms and Doppler measurements produced by coherence tomography, we observed significant increase in blood flow as a result of increased vessel diameter and blood velocity following optical stimulation of cortical neurons. Such distinct responses were not observed in control experiments where the brain of wild-type mice were exposed to the same light pulses.

      Read Full Article
    9. Direct Blood Flow Measurements in a Free RPE-Choroid Graft with Phase-Resolved Doppler OCT

      Direct Blood Flow Measurements in a Free RPE-Choroid Graft with Phase-Resolved Doppler OCT

      Purpose: We directly demonstrated the revascularization in a free retinal pigment epithelium (RPE)-choroid graft with direct blood flow detection by experimental phase-resolved Doppler optical coherence tomography (PRD-OCT). Methods: Seven patients with age-related macular degeneration underwent an RPE-choroid graft translocation in a prospective institutional cohort study. Spectral domain optical coherence tomography (SD-OCT) was used to measure the revascularization stage. With PRD-OCT the presence of flow was imaged postoperatively. Results: The PRD-OCT confirmed flow in three patients when SD-OCT indicated the afferent vessel ingrowth stage, and in all seven patients when the SD-OCT indicated the efferent vessel ingrowth stage. Conclusions: The ...

      Read Full Article
    10. New neuroretinal rim analysis with spectral domain optical coherence tomography, Spectralis (Heidelberg Engineering, Germany). Preliminary study

      New neuroretinal rim analysis with spectral domain optical coherence tomography, Spectralis (Heidelberg Engineering, Germany). Preliminary study

      Introduction Clinical determination of the outer limits of the optic disk (OD) doesn’t always correspond to the true anatomic limits of the optic nerve head (ONH) defined by the Bruch's membrane opening (BMO). A new index analyzing the OD with optical coherence tomography (OCT), “minimal rim width” (BMO-MRW), evaluates the smallest thickness of the neuroretinal rim between the BMO and the internal limiting membrane. The purpose of this study was to evaluate new software for automatic measurement of the BMO-MRW. Materials and methods This study investigated 95 eyes: 40 control eyes and 55 eyes followed and treated for ...

      Read Full Article
    11. Pulsatile motion of trabecular meshwork in a patient with iris cyst by phase-sensitive optical coherence tomography: a case report

      Pulsatile motion of trabecular meshwork in a patient with iris cyst by phase-sensitive optical coherence tomography: a case report

      45-year-old man was diagnosed with a 3 mm × 3 mm iris cyst located at 9 o’clock behind iris and protruding into temporal angle by slit lamp examination, gonioscopy, and ultrasound biomicroscopy (UBM). Phase-sensitive optical coherence tomography (PhS-OCT) was applied on this case for the quantitative measurements of trabecular meshwork (TM) motion. The frequency of TM motion was with the same rhythm of the patient’s peripheral pulse. Its amplitude on the closed angle region showed significant smaller than the open angle region. PhS-OCT can be a useful tool for the diagnosis and follow-up in ocular diseases surrounding iridocorneal angle.

      Read Full Article
    12. Correlation between Fourier-Domain Optical Coherence Tomography Parameters and HbA1c Level and Diabetes Duration in Early Stage Diabetic Retinopathy

      Correlation between Fourier-Domain Optical Coherence Tomography Parameters and HbA1c Level and Diabetes Duration in Early Stage Diabetic Retinopathy

      We examined a significant correlation between Fourier-domain optical coherence tomography (FD-OCT) parameters and the glycosylated hemoglobin A1c (HbA1c) level and duration of diabetes mellitus (DM) in patients at the early stage of diabetic retinopathy (DR). Thirty eyes of 30 patients with early stage DR that were examined at the Chiba University Hospital were studied. The macular map 5 (MM5), the retinal nerve fiber layer thickness, and the ganglion cell complex thickness were obtained by FD-OCT. The coefficients of correlation between these parameters and the HbA1c level and the DM duration were determined by Spearman rank correlation. The thickness of the ...

      Read Full Article
    13. New developments in optical coherence tomography

      New developments in optical coherence tomography

      Purpose of review: Optical coherence tomography (OCT) has become the cornerstone technology for clinical ocular imaging in the past few years. The technology is still rapidly evolving with newly developed applications. This manuscript reviews recent innovative OCT applications for glaucoma diagnosis and management. Recent findings: The improvements made in the technology have resulted in increased scanning speed, axial and transverse resolution, and more effective use of the OCT technology as a component of multimodal imaging tools. At the same time, the parallel evolution in novel algorithms makes it possible to efficiently analyze the increased volume of acquired data. Summary: The ...

      Read Full Article
    14. Optical coherence tomography based microangiography for quantitative monitoring of structural and vascular changes in a rat model of acute uveitis in vivo: a preliminary study

      Optical coherence tomography based microangiography for quantitative monitoring of structural and vascular changes in a rat model of acute uveitis in vivo: a preliminary study

      Uveitis models in rodents are important in the investigation of pathogenesis in human uveitis and the development of appropriate therapeutic strategies for treatment. Quantitative monitoring of ocular inflammation in small animal models provides an objective metric to assess uveitis progression and/or therapeutic effects. We present a new application of optical coherence tomography (OCT) and OCT-based microangiography (OMAG) to a rat model of acute anterior uveitis induced by intravitreal injection of a killed mycobacterial extract. OCT/OMAG is used to provide noninvasive three-dimensional imaging of the anterior segment of the eyes prior to injection (baseline) and two days post-injection (peak ...

      Read Full Article
    15. Wide-field imaging and OCT vs clinical evaluation of patients referred from diabetic retinopathy screening

      Wide-field imaging and OCT vs clinical evaluation of patients referred from diabetic retinopathy screening

      Purpose Compare wide-field Optomap imaging and optical coherence tomography (OCT) with clinical examination in diabetic retinopathy (DR). Methods Patients referred from Diabetic Eye Screening Programmes to three centres underwent dilated ophthalmoscopy and were assigned a DR grade. Wide-field colour imaging and OCT were then examined by the same clinician at that visit and a combined grade was assigned. Independent graders later reviewed the images and assigned an imaging-only grade. These three grades (clinical, combined, and imaging) were compared. The method that detected the highest grade of retinopathy, including neovascularisation, was determined. Results Two thousand and forty eyes of 1023 patients ...

      Read Full Article
    16. Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Purpose To compare signal penetration depth and deep structure-visualization of swept source (SS) and spectral domain (SD)-optical coherence tomography (OCT) with and without enhanced depth imaging (EDI) and B-scan averaging modes. Methods Volume scans were obtained from 20 eyes of healthy volunteers by DRI OCT-1, Spectralis using EDI and B-scan averaging, and Cirrus HD-OCT. The signal penetration depth was measured as the distance between the retinal pigment epithelium and the deepest visible anatomical structure at the foveal center. Visibility and contrast of the choroidoscleral junction and of vascular details within the choroid were assessed across the entire volume using ...

      Read Full Article
    17. Lamina Cribrosa Visibility using Optical Coherence Tomography: Comparison of Devices and Effects of Image Enhancement Techniques

      Lamina Cribrosa Visibility using Optical Coherence Tomography: Comparison of Devices and Effects of Image Enhancement Techniques

      Purpose: To compare the visibility of the lamina cribrosa (LC) in optic disc images acquired from 60 glaucoma and 60 control subjects using three optical coherence tomography (OCT) devices, with and without enhanced depth imaging (EDI) and adaptive compensation (AC). Methods: A horizontal B-scan was acquired through the centre of the disc using two spectral-domain (Spectralis and Cirrus; with and without EDI) and a swept-source (DRI) OCT. AC was applied post-acquisition to improve image quality. To assess LC visibility, four masked observers graded the 1,200 images in a randomised sequence. The anterior LC was graded from 0 to 4 ...

      Read Full Article
    18. Choroidal Hyperreflective Foci in Stargardt Disease Shown by Spectral-Domain Optical Coherence Tomography Imaging Correlation With Disease Severity

      Choroidal Hyperreflective Foci in Stargardt Disease Shown by Spectral-Domain Optical Coherence Tomography Imaging Correlation With Disease Severity

      Importance The presence of choroidal hyperreflective foci in Stargardt disease is, to our knowledge, a potentially new finding. Evaluation of these foci may aid in better understanding of the disease process. Objectives To report the presence of choroidal hyperreflective foci in spectral-domain optical coherence tomography (SD-OCT) images from eyes with Stargardt disease and investigate the relationship between the number of hyperreflective foci and disease severity. Design, Setting, and Participants Twenty-six eyes of 13 patients with a clinical diagnosis of Stargardt disease were evaluated in a retrospective case series. Patient data were collected between January 1, 2009, and August 31, 2014 ...

      Read Full Article
    19. EVOLUTION OF CONTROLLING DIABETIC RETINOPATHY: Changing Trends in the Management of Diabetic Macular Edema at a Single Institution Over the Past Decade

      EVOLUTION OF CONTROLLING DIABETIC RETINOPATHY: Changing Trends in the Management of Diabetic Macular Edema at a Single Institution Over the Past Decade

      Purpose: To report the evolution of treatment in managing diabetic macular edema (DME) in a "real world" clinical setting. Methods: Retrospective observational case series of 1,862 patients treated for DME over the last decade. Change in selection of treatment modalities used for controlling DME, visual acuity, and degree of DME on optical coherence tomography were recorded. Results: Over the past decade, there was a linear decrease in laser use, with exponential growth in the utilization of intravitreal injections. An increase in the frequency of clinic visits from 3 +/- 2 visits per year to 9 +/- 2 visits per year with ...

      Read Full Article
    20. Analysis of optimum conditions of depolarization imaging by polarization-sensitive optical coherence tomography in the human retina

      Analysis of optimum conditions of depolarization imaging by polarization-sensitive optical coherence tomography in the human retina

      Measurement and imaging of depolarization by polarization-sensitive optical coherence tomography (PS-OCT) requires averaging of Stokes vector elements within two- or three-dimensional (3-D) evaluation windows to obtain the degree of polarization uniformity (DOPU). By use of a PS-OCT system with an integrated retinal tracker, we analyze optimum conditions for depolarization imaging, data processing, and segmentation of depolarizing tissue in the human retina. The trade-offs between figures of merit like DOPU imaging sensitivity, efficiency, and susceptibility are evaluated in terms of 3-D resolution. The results are used for a new, detailed interpretation of PS-OCT high-resolution images of the human retinal pigment epithelium ...

      Read Full Article
    21. In vivo imaging of human photoreceptor mosaic with wavefront sensorless adaptive optics optical coherence tomography

      In vivo imaging of human photoreceptor mosaic with wavefront sensorless adaptive optics optical coherence tomography

      Wavefront sensorless adaptive optics optical coherence tomography (WSAO-OCT) is a novel imaging technique for in vivo high-resolution depth-resolved imaging that mitigates some of the challenges encountered with the use of sensor-based adaptive optics designs. This technique replaces the Hartmann Shack wavefront sensor used to measure aberrations with a depth-resolved image-driven optimization algorithm, with the metric based on the OCT volumes acquired in real-time. The custom-built ultrahigh-speed GPU processing platform and fast modal optimization algorithm presented in this paper was essential in enabling real-time, in vivo imaging of human retinas with wavefront sensorless AO correction. WSAO-OCT is especially advantageous for developing ...

      Read Full Article
    22. Spectral domain optical coherence tomography in patients with sickle cell disease

      Spectral domain optical coherence tomography in patients with sickle cell disease

      Aim To evaluate spectral domain optical coherence tomography (SD-OCT) changes in central retina and choroid in patients with sickle cell disease (SCD). Methods Data on visual acuity, severity of sickle cell retinopathy, macular volume scans and choroidal thickness on SD-OCT were analysed from 208 eyes of 107 consecutive patients referred for screening for SCD. The retinal and choroidal thickness of eyes with SCD were also compared with age and ethnicity matched controls. Results 44% of the eyes of patients with SCD showed discrete areas of retinal thinning in the temporal macular area. Proliferative sickle cell retinopathy was more prevalent in ...

      Read Full Article
    23. Bioptigen Awarded $458,000 from North Carolina Biotechnology Center to Advance Intrasurgical OCT System Development

      Bioptigen Awarded $458,000 from North Carolina Biotechnology Center to Advance Intrasurgical OCT System Development

      Bioptigen announced today that it has been awarded a Strategic Growth Loan from the North Carolina Biotechnology Center totaling $458,000 to support development of the company’s Intrasurgical OCT imaging system. Optical Coherence Tomography or ‘OCT’ is a form of highresolution imaging that has been compared to ultrasound imaging, though OCT uses light rather than sound to create the images. Bioptigen’s EnFocusTM Intrasurgical OCT system will provide 3D visualization simultaneous with and coregistered to images from surgical ophthalmic microscopes. Bioptigen is known globally for its FDA-cleared handheld OCT system for pediatric imaging, and for providing industry leading OCT ...

      Read Full Article
    24. Investigation of the normal and pathological development of the macula of the infant human eye using high resolution Optical Coherence Tomography (Thesis)

      Investigation of the normal and pathological development of the macula of the infant human eye using high resolution Optical Coherence Tomography (Thesis)

      The fovea is a specialised retinal area responsible for high spatial vision. Development of the fovea involves centrifugal migration of inner retinal layers (IRLs) away from the fovea and centripetal displacement of the cone photoreceptors into the fovea and is thought to be complete by 5 years of age. Current understanding of human foveal development is limited to studies of few histological specimens. The recent development of hand-held spectral domain optical coherence tomography (HHSDOCT), can overcome this limitation by facilitating large scale in vivo imaging of the infant human retina, both in controls and in conditions such as achromatopsia and ...

      Read Full Article
    577-600 of 6967 « 1 2 ... 22 23 24 25 26 27 28 ... 289 290 291 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Popular Articles

  3. Organizations in the News

    1. (5 articles) Tufts University
    2. (4 articles) UCSF
    3. (3 articles) Thomas Jefferson University
    4. (3 articles) Medical University of Vienna
    5. (3 articles) Oregon Health & Science University
    6. (3 articles) Massachusetts Institute of Technology
    7. (3 articles) Duke University
    8. (3 articles) Northwestern University
    9. (2 articles) Sun Yat-Sen University
    10. (2 articles) Chungnam National University Hospital
    11. (2 articles) Cleveland Clinic
    12. (2 articles) Academic Hospital Maastricht
  4. People in the News

    1. (5 articles) Jay S. Duker
    2. (4 articles) Nadia K. Waheed
    3. (3 articles) Srinivas R. Sadda
    4. (3 articles) Bernhard Baumann
    5. (3 articles) Michael Pircher
    6. (3 articles) Christoph K. Hitzenberger
    7. (2 articles) Robert J. Zawadzki
    8. (2 articles) Cynthia A. Toth
    9. (2 articles) Robert N. Weinreb
    10. (2 articles) John S. Werner
    11. (2 articles) Chan Yun Kim
    12. (2 articles) Friedemann Paul
  5. OCT Companies in the News

    1. (8 articles) Optovue
    2. (6 articles) Carl Zeiss Meditec
    3. (5 articles) Heidelberg Engineering
    4. (3 articles) Topcon Medical Systems
    5. (2 articles) Thorlabs
    6. (1 articles) Praevium Research
    7. (1 articles) Santec
    8. (1 articles) Optopol Technology
    9. (1 articles) OptiMedica
    10. (1 articles) Optos
    11. (1 articles) Bioptigen
  6. OCT Products in the News

    1. (5 articles) Optovue RTVue-100
    2. (5 articles) Heidelberg Spectralis
    3. (5 articles) Zeiss Cirrus HD-OCT
    4. (2 articles) Optopol SOCT Copernicus
    5. (1 articles) Thorlabs OCT Imaging Systems
    6. (1 articles) Zeiss Stratus OCT
    7. (1 articles) Optovue iVue