1. Articles in category: Ophthalmology

    577-600 of 7061 « 1 2 ... 22 23 24 25 26 27 28 ... 293 294 295 »
    1. Optical tomographic apparatus and control method thereof

      Optical tomographic apparatus and control method thereof

      In order to change a size of an imaging area of a tomographic image of an object to be inspected easily, provided is an optical tomographic apparatus for acquiring a tomographic image of an object to be inspected, the optical tomographic apparatus including a control unit for controlling a measuring light path length changing unit to change an optical path length of measuring light in a case where the size of the imaging area of the tomographic image is changed, and for controlling a movable unit for moving a focus lens for focusing the measuring light to the object to ...

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    2. Ultra wide-field optical coherence tomography

      Ultra wide-field optical coherence tomography

      Systems and methods for expanding the field-of-view of ophthalmic scanning devices are presented. An ophthalmic scanning device is designed such that the pivot point of the scanning optics is maintained at a fixed location in the pupil while the scanning optics are rotated about the eye to obtain imaging data over an increased field-of-view than can be achieved by the scanning optics alone. The rotation can be achieved using a singular rotational motion of the scanning optics about a rotational axes coincident with the scanning pivot point or can be achieved using a combination of rotational motion with a second ...

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    3. The changing rates and indications of optical coherence tomography and fundus fluorescein angiography over 5 years

      The changing rates and indications of optical coherence tomography and fundus fluorescein angiography over 5 years

      Purpose. To evaluate the relative frequency of use of fundus fluorescein angiography (FFA) following the introduction of optical coherence tomography (OCT) at a tertiary university ophthalmology practice. Methods. We retrospectively analyzed the demand for and indications of all requests for FFA or OCT during the five years from 2007 to 2011, inclusively, at our tertiary care university hospital department of ophthalmology. Results. In January 2007, out of 194 total imaging studies requested and performed, there were 85 OCTs (43.8% of total imaging studies) and 109 FFAs (56.2%). By January 2011, out of 172 total imaging studies requested and ...

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    4. Anterior segment optical coherence tomography evaluation of ocular graft-versus-host disease: a case study

      Anterior segment optical coherence tomography evaluation of ocular graft-versus-host disease: a case study

      To explore ocular graft-versus-host disease (GVHD), anterior segment optical coherence tomography (AS-OCT) imaging of eyelids, tear meniscus, cornea and conjunctiva is performed in subsequent sessions on a patient who has ocular GVHD after allogeneic related donor stem cell transplant. The OCT results are presented together with those from a normal subject. OCT imaging is promising in visualizing several ocular GVHD manifestations, such as abnormal meibomian gland orifice (MGO), conjunctival keratinization, conjunctival hyperemia and chemosis, corneal epithelium opacification, thinning and sloughing. This case study demonstrates the capability of AS-OCT in the imaging and monitoring of ocular GVHD, which may be useful ...

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    5. Dynamic imaging of accommodation by swept-source anterior segment optical coherence tomography

      Dynamic imaging of accommodation by swept-source anterior segment optical coherence tomography

      Purpose To study the accommodation process in normal eyes using a commercially available clinical system based on swept-source anterior segment optical coherence tomography (AS-OCT). Setting Ophthalmology Department, University of Parma, Italy. Design Evaluation of diagnostic technology. Methods Right eyes were analyzed using swept-source AS-OCT (Casia SS-1000). The optical vergence of the internal coaxial fixation target was adjusted during imaging to obtain monocular accommodation stimuli with different amplitudes (0, 3.0, 6.0, and 9.0 diopters [D]). Overlapping of real and conjugate OCT images enabled imaging of all the anterior segment optical surfaces in a single frame. Central corneal thickness ...

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    6. Haag-Streit UK finalises an exciting agenda for Optometry Tomorrow 2015

      Haag-Streit UK finalises an exciting agenda for Optometry Tomorrow 2015

      Haag-Streit UK (HS-UK), the leading manufacturer and distributor of gold-standard optometry and ophthalmic equipment, is pleased to announce that it will be exhibiting at this year’s Optometry Tomorrow event in Brighton, on the 8th and 9th March, 2015. HS-UK will be exhibiting on stand 30, where it will be showcasing a large selection of its product portfolio, including the recently launched iScan and iFusion OCT devices, the Eidon true colour confocal scanner, DRS retinal camera, Perkins applanation tonometer and Tonosafe disposable prisms. The fully-automated iScan OCT, is easy-to-use and requires minimal training. It has a small footprint and is ...

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    7. Agreement Among Spectral-Domain Optical Coherence Tomography, Standard Automated Perimetry, and Stereophotography in the Detection of Glaucoma Progression

      Agreement Among Spectral-Domain Optical Coherence Tomography, Standard Automated Perimetry, and Stereophotography in the Detection of Glaucoma Progression

      Purpose. The purpose of this study was to evaluate the agreement among spectral-domain optical coherence tomography, standard automated perimetry (SAP), and optic disc stereo photography in the detection of glaucomatous progression. Methods. This was an observational cohort study enrolling 246 eyes (148 patients) followed for an average of 31.8 ± 9 months. Images were obtained every 6 to 12 months with optical coherence tomography (OCT), visual field test, and optic disc stereo photography. Progression was determined with OCT using guided progression analysis (GPA) software, in perimetry with Humphrey field analyzer GPA, and by masked assessment of stereo photograph series. Agreement ...

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    8. Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/ OTI OCT devices in healthy subjects

      Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/ OTI OCT devices in healthy subjects

      ·AIM: To compare retinal nerve fiber layer (RNFL) and macular thickness measurements obtained with the Stratus optical coherence tomography (OCT) and OPKO/OTI OCT devices. ·METHODS: Included in the study were 59 eyes of 30 participants. All measurements for each eye were done on the same day with both devices. Student's paired tests were used to compare the central macular thickness and RNFL measurements of the Stratus OCT and OPKO/OTI OCT. Pearson correlation was used to assess the relationship between the devices. Coefficient of variation (COV) was calculated to assess intersession repeatability. ·RESULTS: Using both the Stratus OCT ...

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    9. Optical coherence tomography predicts visual outcome for pituitary tumors

      Optical coherence tomography predicts visual outcome for pituitary tumors

      We evaluate if the relationship between optical coherence tomography (OCT) of the retinal nerve fibre layer (RNFL) continued over long-term visual recovery in 107 patients undergoing pituitary decompression. Recently, it has been recognized that OCT of RNFL has prognostic value in predicting visual outcomes after surgery for chiasmal compression caused by pituitary tumours. Patients were followed up at three time points: pre-operative (visit 1), 6 –10 weeks post-operative (visit 2) and 9–15 months follow-up (visit 3). We found that patients with thin pre-operative RNFL had more severe visual field defects (mean deviation [MD] -9.22 versus -3.96 decibels ...

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    10. Detection of the progression of retinal nerve fiber layer loss by optical coherence tomography in a patient with glaucomatocyclitic crisis

      Detection of the progression of retinal nerve fiber layer loss by optical coherence tomography in a patient with glaucomatocyclitic crisis

      A 30-year-old man presented with glaucomatocyclitic crisis, also known as Posner–Schlossman syndrome, and acute intraocular pressure elevation. Changes in the longitudinal retinal nerve fiber layer (RNFL) and the cup-to-disc (C/D) ratio of the optic disc were detected by Stratus optical coherence tomography (OCT). The average RNFL thickness in the affected eye was greater than that in the unaffected eye on Day 3 (132.99 μm, C/D ratio: 0.24 vs. 105 μm, C/D ratio: 0.26). However, the RNFL thickness continued to decrease and the C/D ratio progressively increased in the affected eye over 12 ...

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    11. University of Miami Receives NIH Grant for Advanced Imaging for Diabetic Retinopathy

      University of Miami Receives NIH Grant  for Advanced Imaging for Diabetic Retinopathy

      University of Miami Receives a 2015 NIH Grant for $155,387 for Advanced Imaging for Diabetic Retinopathy. The principal investigator is Delia Cabrera Debuc. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Diabetic retinopathy (DR) is a major cause of visual loss in diabetic individuals that presents a significant diagnostic challenge. Advances in preventing vision loss in these individuals are hindered by limited understanding of mechanisms underlying DR and the altered relationships between the retinal neural tissue and retinal vasculature. Therefore, an objective test for the early diagnosis and evaluation of ...

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    12. Acute Retinal Pigment Epitheliitis: Spectral Domain Optical Coherence Tomography, Fluorescein Angiography, and Autofluorescence Findings

      Acute Retinal Pigment Epitheliitis: Spectral Domain Optical Coherence Tomography, Fluorescein Angiography, and Autofluorescence Findings

      A 17-year-old presented with central and paracentral scotomas in his right eye for one week. There was no remarkable medical or ocular history. Blood analyses were within normal range. At presentation both eyes’ best-corrected visual acuities were 20/20. Slit-lamp examination result was normal. Fundus examination revealed yellow-white hypopigmented areas in the macula. Fluorescein angiography (FA) showed hypofluorescence surrounded by ring of hyperfluorescence. Fundus autofluorescence (FAF) was slightly increased. Spectral domain optical coherence tomography (SD-OCT) showed disruption of IS/OS junction with expansion of abnormal hyperreflectivity from retinal pigment epithelium to the outer nuclear layer (ONL). One month later fundus ...

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    13. Assessment of lower tear meniscus measurements obtained with Keratograph and agreement with Fourier-domain optical-coherence tomography

      Assessment of lower tear meniscus measurements obtained with Keratograph and agreement with Fourier-domain optical-coherence tomography

      Aims To compare intraobserver repeatability and interobserver and intersession reproducibility of lower tear meniscus height measurements (LTMH) obtained with the new Keratograph 5M and a Fourier-domain optical-coherence tomography (OCT; Spectralis OCT) and to assess the agreement between the two devices. Methods This is a observational cross-sectional study. Thirty eyes of 30 normal subjects were randomly imaged twice with both devices in our setting. Two examiners randomly made LTMH measurements using the devices. To assess intraobserver repeatability and interobserver and intersession reproducibility within-subject SD (S w ), test–retest repeatability, coefficient of variation (CoV) and intraclass correlation coefficients (ICCs) were calculated. Agreement ...

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    14. Corneal graft evaluation based on optical coherence tomography image

      Corneal graft evaluation based on optical coherence tomography image

      An OCT image of an eye which has been subject to a DSAEK corneal transplant, in which a Descement's membrane in the cornea has been replaced by a graft, is processed to identify the outline of the graft. The process includes the steps of: computationally extracting the boundary of the cornea including the graft; computationally detecting the corners of the graft; computationally extracting points on the boundary between the graft and the original cornea; and computationally fitting the points on the boundary between the graft and the original cornea smoothly into a curve. The outline of the graft is ...

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    15. Evaluating glaucoma damage: emerging imaging technologies

      Evaluating glaucoma damage: emerging imaging technologies

      The use of ocular imaging tools to estimate structural and functional damage in glaucoma has become a common clinical practice and a substantial focus of vision research. The evolution of the imaging technologies through increased scanning speed, penetration depth, image registration and development of multimodal devices has the potential to detect the pathology more reliably and in earlier stages. This review is focused on new ocular imaging modalities used for glaucoma diagnosis.

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    16. Eyes with Large Disc Cupping and Normal Intraocular Pressure: Using Optical Coherence Tomography to Discriminate Those With and Without Glaucoma

      Eyes with Large Disc Cupping and Normal Intraocular Pressure: Using Optical Coherence Tomography to Discriminate Those With and Without Glaucoma

      We evaluated the ability of spectral-domain optic coherence tomography (SD-OCT) to differentiate large physiological optic disc cupping (LPC) from glaucomatous cupping in eyes with intraocular pressure (IOP) within the normal range. We prospectively enrolled patients with glaucoma or presumed LPC. Participants had optic discs with confirmed or suspected glaucomatous damage (defined as a vertical cup-to-disc ratio≥0.6), and all eyes had known untreated IOP<21 mmHg. For glaucomatous eyes, a reproducible glaucomatous visual field (VF) defect was required. LPC eyes required normal VF and no evidence of progressive glaucomatous neuropathy (follow-up≥30 months). Peripapillary retinal nerve fiber layer (pRNFL ...

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    17. Analysis of choroidal folds in acute Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography

      Analysis of choroidal folds in acute Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography

      Purpose To characterize patients with Vogt–Koyanagi–Harada (VKH) disease with choroidal folds (CFs) and determine how the foveal choroidal thickness changes after initial treatment using high-penetration optical coherence tomography (HP-OCT). Methods In this retrospective observational study, we analyzed 42 eyes of 21 patients with new-onset VKH disease to determine the demographic and clinical differences between patients with and without CFs. Results Twenty-four eyes (57.1 %) of 13 patients with VKH disease had CFs. The mean age ( p  = 0.0009) of patients with CFs was significantly higher than that of those without CFs (49.1 vs 39.4 years respectively ...

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    18. EFFECT OF PROPHYLACTIC BROMFENAC 0.09% ON CYSTOID MACULAR EDEMA ASSESSED USING OPTICAL COHERENCE TOMOGRAPHY QUANTIFICATION OF TOTAL MACULAR VOLUME AFTER CATARACT SURGERY

      EFFECT OF PROPHYLACTIC BROMFENAC 0.09% ON CYSTOID MACULAR EDEMA ASSESSED USING OPTICAL COHERENCE TOMOGRAPHY QUANTIFICATION OF TOTAL MACULAR VOLUME AFTER CATARACT SURGERY

      PURPOSE : To evaluate the efficacy of prophylactic administration of the topical nonsteroidal anti-inflammatory drug (NSAID) Bromfenac 0.09% on acute (within 4 weeks of surgery) cystoids macular edema (CME) and total macular volume (TMV) in patients having phacoemulsification cataract surgery. SETTING : Department of Ophthalmology, shantiram general hospital, nandyal. METHODS : This open-label nonmasked randomized (random number assignment) study comprised 100 eyes. Exclusion criteria included hypersensitivity to the NSAID drug class, aspirin/NSAID-induced asthma, and pregnancy in the third trimester. Bromfenac 0.09%was administered starting 1 day before surgery and for 28 days after surgery for a total of 30 days ...

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    19. Measurement of Subfoveal Choroidal Thickness in Pseudoexfoliation Syndrome Using Enhanced Depth Imaging Optical Coherence Tomography

      Measurement of Subfoveal Choroidal Thickness in Pseudoexfoliation Syndrome Using Enhanced Depth Imaging Optical Coherence Tomography

      Background/Aim: Pseudoexfoliation (PSX) syndrome is associated with blood flow disturbances; however, its exact effect on choroidal blood flow and thickness remains to be elucidated. This study compared subfoveal choroidal thickness in normal eyes and in eyes with PSX using enhanced depth imaging optical coherence tomography (EDI-OCT). Methods: This prospective, cross-sectional study included 35 eyes of 35 patients (20 males, 15 females) with unilateral or bilateral PSX and 26 eyes of 26 healthy volunteers (13 males, 13 females). Besides a comprehensive ocular and physical examination, all subjects underwent EDI-OCT examination using an Optovue RTVue OCT device (Optovue Inc., Fremont, Calif ...

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    20. Evaluation of ischemic diabetic maculopathy with Fourier-domain optical coherence tomography and microperimetry

      Evaluation of ischemic diabetic maculopathy with Fourier-domain optical coherence tomography and microperimetry

      Objective To evaluate the efficacy of high-speed Fourier-domain optical coherence tomography (FD-OCT) and fundus microperimetry (MP-1) in identifying the anatomic and functional features of ischemic diabetic maculopathy. Design Prospective noninterventional study. Participants Forty-two consecutive eyes (23 patients) with ischemic diabetic maculopathy and 40 normal eyes (25 control subjects) were included in this study. Methods Best corrected visual acuity, ganglion cell complex (GCC) thickness measured with FD-OCT, and central light sensitivity recorded with MP-1 were evaluated. Results GCC thickness and light sensitivity were significantly reduced in all affected eyes versus control eyes. logMAR BVCA was significantly correlated with mean macular sensitivity ...

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    21. Prevalence of vitreomacular interface abnormalities on spectral domain optical coherence tomography of patients undergoing macular photocoagulation for centre involving diabetic macular oedema

      Prevalence of vitreomacular interface abnormalities on spectral domain optical coherence tomography of patients undergoing macular photocoagulation for centre involving diabetic macular oedema

      Aim Macular traction may influence the formation and response to treatment of diabetic macular oedema (DME). The aim of this study was to determine the prevalence and associations of spectral domain optical coherence tomography (SD-OCT) evident epiretinal membrane (ERM) and/or partial vitreomacular separation (pVMS) in consecutive patients undergoing macular photocoagulation for centre involving DME. Methods A single-centre retrospective cross-sectional observational study. Results 198 eyes of 198 patients were included. Twelve per cent of eyes demonstrated pVMS and 14% ERM. All cases of pVMS had vitreoretinal adhesion located in the Early Treatment Diabetic Retinopathy Study grid central 1 mm subfield ...

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    22. Comparative evaluation of time domain and spectral domain optical coherence tomography in retinal nerve fiber layer thickness measurements

      Comparative evaluation of time domain and spectral domain optical coherence tomography in retinal nerve fiber layer thickness measurements

      Introduction: Before any new device can replace another for use in clinical practice, it is imperative that its reproducibility, diagnostic accuracy, and ability to detect changes over time are tested. Objective: To evaluate retinal nerve fiber layer (RNFL) measurements between two optical coherence tomography (OCT) systems: the Stratus OCT, a time domain system, and the Cirrus HD-OCT, a spectral domain system (both by Carl Zeiss Meditec, Inc., Dublin, CA). Materials and methods: An observational cross-sectional study was carried out involving 20 eyes with primary open angle glaucoma and 32 eyes of healthy controls. One eye of each patient was imaged ...

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    23. Retinal nerve fibre layer thickness in a healthy Nepalese population by spectral domain optical coherence tomography

      Retinal nerve fibre layer thickness in a healthy Nepalese population by spectral domain optical coherence tomography

      Objective : To determine the normal values for peripapillary retinal nerve fibre layer thickness (RNFL) measured by spectral domain optical coherence tomography (SD- OCT) in a healthy Nepalese population and to compare the RNFL thicknesses between the genders and among the various age groups. Material and methods : One hundred and fifty six eyes of 156 healthy Nepalese subjects (66 males and 88 females) of various age groups were enrolled in this observational, cross-sectional, hospital-based study. The peripapillary RNFL of the randomly chosen eye of each subject was imaged with a high resolution SD-OCT (Spectralis HRA+OCT, Heidelberg Engineering). The RNFL thickness ...

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    24. University of Washington Receives NIH Grant to Study Non-invasive Real-Time Label-Free 3D Imaging of Retinal Microcirculation.

      University of Washington Receives NIH Grant to Study Non-invasive Real-Time Label-Free 3D Imaging of Retinal Microcirculation.

      University of Washington Received a 2015 NIH Grant to Study Non-invasive real-time label-free 3D imaging of retinal microcirculation. The principal investigator is Ruikang Wang. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. Non-invasive and label-free imaging techniques for assessing retinal blood perfusion in humans - down to capillary-level resolution, are of paramount importance for improved understanding, diagnosis, treatment and management of diseases that have a vascular component in their pathogenesis, e.g., age related macular degeneration (AMD), diabetic retinopathy (DR), and open angle glaucoma (OAG). Invasive imaging techniques, e.g., fluorescein angiography ...

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