1. Optical Coherence Tomography News

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    1. Michelson Diagnostics delivers First Sale in the USA

      Michelson Diagnostics delivers First Sale in the USA
      Orpington, UK, July 14th, 2009: Michelson Diagnostics Limited (MDL), the UK manufacturer of Multi-Beam Optical Coherence Tomography (OCT) scanners, is pleased to announce delivery of a unit to its first US customer. The EX1301 OCT Microscope is being used by the Center for Pharmacogenomics, Washingt
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    2. Feature Of The Week 7/11/09: High temporal resolution OCT using image-based retrospective gating

      Feature Of The Week 7/11/09: High temporal resolution OCT using image-based retrospective gating
      Feature Of The Week: 7/11/09: Studying abnormalities during heart development in the embryo is crucial for the understanding of congenital heart disease. Our group has been developing specialized OCT-based instruments and software and applying them to the study of the developing heart in avian and mouse models [1-5]. The developing morphology is of interest, but even more interesting is the development of cardiac function, the ability of the heart to contract and pump blood. Several groups have shown that mechanical forces influence the morphogenesis of the developing heart [6-9].
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    3. Michelson Diagnostics announces launch of VivoSight Multi-Beam OCT scanner

      Michelson Diagnostics announces launch of VivoSight Multi-Beam OCT scanner
      London, 8 July 2009: Michelson Diagnostics Limited (MDL), the UK manufacturer of Multi-Beam Optical Coherence Tomography (OCT) scanners, is pleased to formally announce the launch of its ‘VivoSight’ Multi-Beam OCT scanner. The scanner uses the high resolution capability of the company’s propri
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    4. Feature Of The Week 7/5/09: Single-body lensed-fiber scanning probe actuated by magnetic force for optical imaging

      Feature Of The Week 7/5/09: Single-body lensed-fiber scanning probe actuated by magnetic force for optical imaging
      Feature Of The Week: 7/5/09: In recent years, hand-held and endoscopic optical coherence tomography (OCT) has been investigated for a variety of clinical and therapeutic applications. As critical factors affecting the OCT performance, compactness and scanning speed of the sample arm of an OCT system have been widely recognized. Therefore, many scanning schemes have been investigated such as piezoelectric, rotational-micro-electro-mechanical-system (MEMS), electrostatic, and bimorph scanners. However, the piezoelectric scanner required high driving voltage, the MEMS scanner needs a complicated fabrication process, and the performance of the bimorph was material dependent and sensitive to external parameters, such as temperature ...
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    5. Feature Of The Week: 6/26/09: Fully Automatic Three-Dimensional (3D) Quantitative Analysis of Intracoronary Optical Coherence Tomography: Method and Validation

      Feature Of The Week: 6/26/09: Fully Automatic Three-Dimensional (3D) Quantitative Analysis of Intracoronary Optical Coherence Tomography: Method and Validation
      Feature Of The Week: 6/26/09: Optical Coherence Tomography continues to make tremendous progress in the diagnosis and treatment of coronary artery disease and second generation systems have accelerated that progress. The Thoraxcenter has been a leading organizations in this field as can be seen by clicking the Cardiology tag an scrolling down to "Organizations in the News". Described below is some recent work by Nico Bruining et al which discusses fully automatic three-dimensional quantitative analysis of intracoronary OCT.
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    6. Michelson Diagnostics Opens US Offices And Appoints US Business Development Manager

      Michelson Diagnostics Opens US Offices And Appoints US Business Development Manager
      Orpington, UK, June 23rd, 2009: Michelson Diagnostics Limited (MDL) announced today that it has opened a sales and support office in the USA. The office is located in Fuquay-Varina, (in the Research Triangle vicinity of Raleigh-Durham), North Carolina, and is headed by Kevin C. Oakley, Business Development Manager (US) for Michelson Diagnostics. The new office will act as a hub for growth of MDL’s business in the field of Optical Coherence Tomography (OCT) imaging, which has great applications potential in fields such as skin cancer diagnosis, genetics research and tissue engineering development. The company has no FDA-approved clinical products ...
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    7. Feature Of The Week 6/21/09: Laparoscopic optical coherence tomography imaging of human ovarian cancer

      Feature Of The Week 6/21/09: Laparoscopic optical coherence tomography imaging of human ovarian cancer
      Feature Of The Week 6/21/09: Ovarian cancer is the fourth leading cause of cancer-related death among women in the US, largely attributed to late detection due to unreliable symptomology and screening tools without adequate resolution and specificity. As a result, ovarian cancer is often diagnosed at advanced stages, after invasion of adjacent structures or metastasis to a distant site. Women with regional and distant disease have a 5-year survival rate of 71% and 30% (at best), respectively. If diagnosed at the localized stage, the 5-year survival rate is 92%; however, only about 19% of all cases are detected ...
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    8. Professor Fujimoto was presented with the Hounsfield Medal at Imperial College London

      Professor Fujimoto was presented with the Hounsfield Medal at Imperial College London
      The annual Hounsfield memorial lecture was instituted by the Imperial College London Imaging Sciences Centre to recognise the contribution of Sir Godfrey Hounsfield in the development of medical imaging systems. The lecture has been designed as an opportunity for a world leading researcher in imaging science to review the latest developments in imaging science. This is supported by a range of posters produced by imaging related research groups in Imperial which demonstrate the scope and depth of research going on at the College. The fifth lecture in the series was given on 8th June 2009 by Professor James Fujimoto from ...
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    9. Feature Of The Week 6/14/09: Assessing Sirolimus-Eluting Stent Implantation by Optical Coherence Tomography

      Feature Of The Week 6/14/09: Assessing Sirolimus-Eluting Stent Implantation by Optical Coherence Tomography
      Feature Of The Week 6/14/09: Heart disease is a leading cause of death in the industrialize world. Since the early 1990's when the Palmaz bare medal stent was introduced, stents have continued to play a major role in the treatment of heart disease. The stent market is over $5B and there is intense pressure to improve stent technology from both a healthcare and market share perspective. Optical Coherence Tomography is unique in its ability to provide critical information in assessing the impact, safety, and efficacy of stents. Some recent work by researchers at Kobe University and Stanford ...
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    10. Feature Of The Week 6/7/09: Optical micro-angiography: A label-free imaging technique to image blood perfusion within microcirculation tissue beds

      Feature Of The Week 6/7/09: Optical micro-angiography: A label-free imaging technique to image blood perfusion within microcirculation tissue beds
      Feature Of The Week 6/7/09: Researchers from the Biophotonics and Imaging Laboratory (BAIL) at Oregon Health & Science University (OHSU) have pioneered a new volumetric imaging modality, optical micro-angiography (OMAG) that is capable of imaging blood perfusion, down to capillary level resolution, within microcirculation tissue beds in vivo. Unlike Doppler OCT to image blood flow, OMAG explores implicitly the phase information embedded in the OCT spectral interferograms. By using heterodyne technology, OMAG method effectively separates the scattering signals caused by the moving scatters, for example moving blood cells, from the scattering signals backscattered by the static tissue background, i ...
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    11. Michelson Diagnostics continues Expansion with the Hire of a New Senior Imaging Scientist

      Michelson Diagnostics continues Expansion with the Hire of a New Senior Imaging Scientist
      Orpington, UK, June 1st, 2009: Michelson Diagnostics (MDL) is pleased to announce the appointment of Dr Florian Bazant-Hegemark as Senior Imaging Scientist. Dr Bazant-Hegemark, known as "Flo", has been working in optical coherence tomography (OCT) in his position as a Clinical Scientist in the biophotonics research group at Gloucestershire Royal Hospital NHS Foundation Trust where he co-authored a landmark article in the Biophotonics journal in 2007. "We are most fortunate that Flo has joined our company," said Jon Holmes, MDL’s CEO. "His practical experience will be invaluable to help customers use the problem-solving power of Multi-Beam OCT. The timing ...
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    12. Feature Of The Week 5/31/09: Evaluation of oral vascular anomalies using optical coherence tomography

      Feature Of The Week 5/31/09: Evaluation of oral vascular anomalies using optical coherence tomography
      Feature Of The Week 5/31/09: The continued technological and application progress in the field of Optical Coherence Tomography (OCT) is rapidly bringing to fruition the concept of an optical biopsy – the ability to non-invasively image in-situ tissue at a resolution approaching histopathology. There are numerous applications for an optical biopsy including in the oral vascular where researchers from the National Center for Geriatrics and Gerontology in Japan, Santec, and Tokyo Medical and Dental University have shown interesting results using a hand-held scanner. These slides present results from a recent study whose purpose was to present the first OCT ...
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    13. GE Healthcare and LightLab Imaging Inc. Collaborate on Cardiovascular Imaging

      GE Healthcare and LightLab Imaging Inc. Collaborate on Cardiovascular Imaging
      Barcelona, SPAIN and Westford, MA, USA; May 19, 2009: GE Healthcare, a global leader in healthcare solutions and LightLab Imaging Inc., a market leader in optical imaging, today announced a collaboration that enables improved workflow between GE Healthcare’s Innova® cardiovascular X-ray system and LightLab Imaging Inc.’s C7-XR™ Optical Coherence Tomography system. Both the C7-XR and Innova systems will be featured this week at the annual meeting of EuroPCR, the official congress of the EAPCI (European Association for Percutaneous Cardiovascular Interventions) in Barcelona, Spain. The LightLab C7-XR is available for purchase from LightLab in twenty countries in Europe, Asia ...
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    14. Feature Of The Week 5/24/09: Investigation of Oddi sphincter structure by optical coherence tomography in patients with biliary-type 1 dysfunction.

      Feature Of The Week 5/24/09: Investigation of Oddi sphincter structure by optical coherence tomography in patients with biliary-type 1 dysfunction.
      Feature Of The Week 5/24/09: Researchers from the Scientific Institute of San Raffaele, Azienda Ospedaliera San Paolo - University Hospital in Milan, and University of Milan have done leading research in the application of Optical Coherence Tomography to the area of gastroenterology and gastrointestinal endoscopy. These slide illustrate some of their recent work entitled "Investigation of Oddi Sphincter Structure by Optical Coherence Tomography in Patients with Biliary-Type 1 Dysfunction: A Pilot In Vivo Study". Type 1 sphincter of Oddi (SO) dysfunction is a clinical entity characterized by biliary-type pain, elevated liver biochemical tests, and common bile duct (CBD) dilatation ...
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    15. Coronary Artery Pullback Video using World's First Commercially Available FD-OCT Imaging System from Lightlab Imaging

      Coronary Artery Pullback Video using World's First Commercially Available FD-OCT Imaging System from Lightlab Imaging
      This week Lightlab Imaging Incorporated announced the worlds first commerical Fourier domain detection optical coherence tomography imaging system for the coronary artery representing a major step forward for application of OCT in cardiology. This video illustrates micron level resolution imaging of the coronary artery with the capability to scan a 40mm artery segment in less than 3 seconds with a single non-occlusive catheter. For more information see Press Release.
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    16. Feature Of The Week 5/17/09: Comparison of CCT and ACD measurements using 3 imaging technologies in normal eyes and after pIOL implantation

      Feature Of The Week 5/17/09: Comparison of CCT and ACD measurements using 3 imaging technologies in normal eyes and after pIOL implantation
      Feature Of The Week 5/17/09: Measurements of central corneal thickness (CCT) are important in the assessment of a variety of corneal diseases, the precision of intraocular pressure readings, and eligibility of patients considering refractive surgery. Currently, a variety of non-contact imaging technologies are available to measure CCT, such as the Zeiss Visante Optical Coherence Tomography (OCT), Orbscan II, and Pentacam. These non-contact devices are becoming more popular, as they eliminate the disadvantages of ultrasound biometry, such as the risk of corneal abrasions and infections due to corneal contact, as well as discomfort experienced by the patient. The mentioned ...
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    17. Feature Of The Week 5/10/09: Video of Dr. Thomas Lee from The Vision Center at Children’s Hospital Los Angeles using Bioptigen Handheld OCT Scanner to Treat Retinopathy in Premature Babies

      Feature Of The Week 5/10/09: Video of Dr. Thomas Lee from The Vision Center at Children’s Hospital Los Angeles using Bioptigen Handheld OCT Scanner to Treat Retinopathy in Premature Babies
      Feature Of The Week 5/10/09: Dr. Thomas C. Lee is director of the Retinal Institute at The Vision Center at Childrens Hospital Los Angeles. Dr. Lee has developed a new surgical procedure for premature babies to address the disease Retinopathy of Prematurity (ROP) that utilizes a hand held spectral domain detection optical coherence tomography (OCT) probe developed by Bioptigen. Video courtsey of Amanda Hedlund at the The Vision Center at Childrens Hospital Los Angeles. Video introduction by Dana Delany of TV series "Desperate Housewives".
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    18. Feature Of The Week 5/3/09: Fundus Autofluorescence and Structure in Stargardt Disease

      Feature Of The Week 5/3/09: Fundus Autofluorescence and Structure in Stargardt Disease
      Feature Of The Week 5/3/09: Macular degeneration is a medical condition usually of older adults which results in a loss of vision in the center of the visual field (the macula) because of damage to retinal structure. Stargardt's disease is the most common form of inherited juvenile macular degeneration. It is a severe form of Macular degeneration that begins in late childhood, leading to legal blindness. Stargardt's disease affects approximately one in 10,000 children. Currently, there is no effective treatment for Stargardt's disease. OCT and other imaging techniques are used in a variety of ...
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    19. Feature Of The Week 4/26/09: Linear-Wavenumber Spectrometer for High-Speed Spectral-Domain Optical Coherence Tomography

      Feature Of The Week 4/26/09: Linear-Wavenumber Spectrometer for High-Speed Spectral-Domain Optical Coherence Tomography
      Feature Of The Week 4/26/09: Spectral-domain optical coherence tomography (SD OCT) is based on measuring of optical spectrum of sum of two interfering waves: the reference one and the backscattered from the object one. The information about object inner structure is reconstructed by inverse Fourier transform of optical spectrum. The Fast Fourier transform (FFT) is used to get maximized processing speed. Using FFT has in mind strongly equally spaced (by argument) samples (in SD OCT argument is optical frequency of receiving light). In real systems this equidistance is guaranteed only with some accuracy. This results in distortion and ...
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    20. Feature Of The Week 4/19/09: Dual Window Method for Processing SOCT Signals with High Spectral and Temporal Resolution

      Feature Of The Week 4/19/09: Dual Window Method for Processing SOCT Signals with High Spectral and Temporal Resolution
      Feature Of The Week 4/19/09. In spectroscopic optical coherence tomogramphy (SOCT), both the intensity and the spectrum of scattered light is obtained; thus, through spectral analysis and coherence gating, one can increase the information content of OCT signals and obtain functional information of tissue. Moreover, in order to resolve depth varying signals, several methods have been employed including short time Fourier transform (STFT), Cohen’s time frequency distributions (TFDs), and model based TFDs. Unfortunately, these methods suffer from several drawbacks, including a trade-off between temporal/depth and spectroscopic/wavelength resolution, the requirement that knowledge of complex fields rather ...
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    21. Feature Of The Week 4/5/09: In-vivo Optical Coherence Tomography from a Hand-Held Probe

      Feature Of The Week 4/5/09: In-vivo Optical Coherence Tomography from a Hand-Held Probe
      Feature of the week 4/5/09: Many OCT systems, particularly microscopy systems, have fixed probe modules where samples are brought to the OCT system. Several papers have been published on hand-held probes which instead bring the OCT system to the sample. Applications such as cardiology and endoscopy have long brought the light to the sample, but the engineering challenges of hand-held microscopy, ophthalmology, or NDE application are quite different. Several factors enable hand-held probes including: fiber-optic systems decouple the OCT engine from the probe; speed capabilities of Fourier domain detection minimize motion induced artifacts; and improvements in miniature scanning ...
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    22. OCT imaging consultants/applications-experts sought by Michelson Diagnostics

      OCT imaging consultants/applications-experts sought by Michelson Diagnostics
      Michelson Diagnostics seeks consultants with expertise in imaging, especially OCT, to assist with demonstrations and evaluation trials of its Multi-Beam OCT technology at customer sites in US and Germany. The consultants will provide local technical expertise, to help scientific and clinical custome
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    23. Ophthalmic Optical Coherence Tomography Market: Past, Present, & Future

      In 1992 the first commercial optical coherence tomography (OCT) company was started. It was called Advanced Ophthalmic Devices (AOD) and as the name implies was focused on the ophthalmology market. AOD grew out of research at the Massachusetts Institute of Technology, Massachusetts Eye and Ear Infir
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