1. Optical Coherence Tomography News

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    1. Feature Of The Week 2/7/10: Manual-Scanning Optical Coherence Tomography (OCT) Probe Based on Position Tracking

      Feature Of The Week 2/7/10: Manual-Scanning Optical Coherence Tomography (OCT) Probe Based on Position Tracking
      Feature Of The Week 2/7/10: Optical Coherence Tomography (OCT) is now an important modality in the field of biomedical imaging for its high resolution and non-invasive nature. People have been developing OCT endoscopes to penetrate into deep biological tissues and extend the limited light penetration depth in near infrared wavelength region. Different ways of steering the probing beam have been developed over the years. As most of them need some form of mechanical actuation, they usually come with the associated cost of additional hardware that must be integrated onto the probes. An OCT probe that can be manually ...
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    2. Biomedical Optics Workshop at Boston University Photonics Center

      Biomedical Optics Workshop at Boston University Photonics Center
      The exponential growth of Biomedical Optics in the last decade, resulting from the application of maturing technologies in optical imaging, integrated optics, fiber optics, lasers, detectors, and nano-technology to the medical field, requires practicing professionals to become knowledgeable about a whole new generation of opto-electronic medical equipment. Due to the efforts of innovative researchers, a wide variety of advanced optical techniques have been developed (diffused optical imaging, multi-photon microscopy, optical tomography) for clinical monitoring of diseases in vivo and ex vivo, and pathogen detection. These techniques are becoming essential in Genomics, Proteomics, Biomedical diagnostics, and therapeutics to mention a few ...
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    3. Feature Of The Week 1/31/10: Mechanical Compression Effect in Optical Coherence Tomography Imaging of Biotissues

      Feature Of The Week 1/31/10: Mechanical Compression Effect in Optical Coherence Tomography Imaging of Biotissues
      Feature Of The Week 1/31/10: The majority of pathological processes in biotissues lead to their structural changes. The information about such changes is important for correct diagnostics and choice of proper treatment strategy. These changes can be detected using the optical coherence tomography (OCT). For application of OCT diagnostics in endoscopic studies the development of sufficient OCT-probes is required. However, the developed endoscopic OCT-probes are contact and their usage induces compression of the sample under study. Thus, the study of compression effect on the obtained OCT images of biotissues is of importance. In addition some pathological states could ...
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    4. LightLab Imaging Receives Prism Award

      LightLab Imaging Receives Prism Award
      Westford, MA, January 27, 2010 – LightLab Imaging Inc., the pioneer and leader in the development of Optical Coherence Tomography (OCT) for vascular and other imaging applications, today announced the receipt of the Prism Award for Photonics Innovation in the life sciences category. This award was presented by Laurin Publishing and SPIE during SPIE Photonics West on January 27, 2010 to honor photonics innovation. Awards were presented to nine other products in eight other categories. “It is an honor to be recognized by SPIE with this Prism Award.” said Joe Schmitt, Chief Technology Officer of LightLab Imaging. “This shows how the ...
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    5. Feature Of The Week 1/24/10: Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography

      Feature Of The Week 1/24/10: Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography
      Feature Of The Week 1/24/10: David Huang was one of the co-inventors of Optical Coherence Tomography and has continued to do pioneering research in OCT from his early days doing PhD work at the Massachusetts Institute of Technology to his current position as a professor of ophthalmology at the Keck School of Medicine at the University of Southern California. A topic recently studied by Dr. Huang and his collaborators is Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography. Glaucoma is diagnosed clinically by observing optic nerve cupping and visual field defects. Although histopathological ...
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    6. Feature Of The Week 1/17/10: Full-Field Optical Coherence Tomography for the Rapid Estimation of Epidermal Thickness

      Feature Of The Week 1/17/10: Full-Field Optical Coherence Tomography for the Rapid Estimation of Epidermal Thickness
      Feature Of The Week 1/17/10: A number of recent developments in non-invasive physiological monitoring of the human body have demonstrated a high potential for the use of such techniques in the in vivo estimation of various clinically relevant parameters such as haemoglobin content and its’ oxygen saturation, amount of glycated haemoglobin, alcohol, etc. One of the most promising of those parameters is the non-invasive estimation of tissue glucose concentration which can potentially bring a great relief for the patients with Diabetes Mellitus, for whom the tight glucose control is the major requirement for long term therapy. The majority ...
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    7. Announcement of Michelson-Diagnostics OCT-News Student Travel Grant Winner

      Announcement of Michelson-Diagnostics OCT-News Student Travel Grant Winner
      On November 4th OCT News in partnership with Michelson Diagnostics and funded by a generous donation from Michelson Diagnostics, announced a $1,500 student travel grant opportunity. We received numerous submissions all of which displayed outstanding work. The awards were ranked by OCT News, Michelson Diagnostics, and an independent 3rd party based on results, presentation, novelty, and potential utility. The final rankings of the top 3rd of the presentations were nearly identical and choosing a winner was difficult. The winner was Yan Wang for her submission on “Quantitative assessment of peripheral nerve damage using polarization-sensitive optical coherence tomography”. Ms. Wang ...
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    8. Despite Economic Crisis, OCT Market Grows in 2009, Reaching $315 Million

      Despite Economic Crisis, OCT Market Grows in 2009, Reaching $315 Million
      January 6, 2010—Mountain View, CA—Optical coherence tomography (OCT) is continuing its rapid expansion as a fast, high-resolution imaging tool for clinical diagnostics. Systems sales grew in 2009, despite the economic crisis, with compound annual growth rate of 20% expected through 2014. The market for OCT systems is entering a new phase as it moves beyond ophthalmology and is applied to new medical specialties. These are among the findings in a new report, OCT 2010: Technology, Applications, and Markets, from market research firm Strategies Unlimited, the research unit for PennWell. OCT systems use advanced optical techniques to construct micron-scale ...
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    9. Happy New Year to OCT News Users!

      Happy New Year to OCT News Users!
      I would like to wish all the users of OCT News a Happy New Year and thank all of you for the support OCT News has received in 2009. The popularity of the website has grown dramatically since it started in October 2007. This can be measured in terms of the large number of users subscribed to the daily or weekly newsletter, the even larger number of page views (passing half a million), the fact that OCT News is routinely accessed from over 170 countries, and the availability of OCT News results on all major search engines. Looking forward to ...
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    10. Feature Of The Week 12/13/09: Using Optical Coherence Tomography to Study Wood and Wood Finishes on an 18th century Italian violin

      Feature Of The Week 12/13/09: Using Optical Coherence Tomography to Study Wood and Wood Finishes on an 18th century Italian violin
      Feature Of The Week 12/13/09: When available, non-contact, non-destructive and in situ techniques are very much favoured to study the cultural heritage artefacts that are precious witnesses of the past, by limiting the number of micro-samples. Optical Coherence Tomography (OCT) is then especially attractive. OCT potentially allows a better representativity than techniques which require a sample, by increasing the number of instruments studied and the number of measurements on each instrument. During the past few years, many applications of OCT have been reported in the field of art technology and art conservation. An original full-field time-domain OCT system ...
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    11. Feature Of The Week 12/6/09: Cascaded Wavelength Swept Amplified Spontaneous Emission Source for Optical Coherence Tomography

      Feature Of The Week 12/6/09: Cascaded Wavelength Swept Amplified Spontaneous Emission Source for Optical Coherence Tomography
      Feature Of The Week 12/6/09: Due to increasing interest in Optical Coherence Tomography (OCT) using wavelength swept lasers (SS-OCT), huge efforts have been made by both research and commercial organizations around the world to push the performance of such sources and with it OCT system capabilities. This includes sweep repetition rate, power, new wavelengths, coherence length, and more. One of the drawbacks of standard wavelength-swept lasers is the fact that lasing has to build up from amplified spontaneous emission repetitively within several roundtrips of the light, limiting the maximum achievable sweep speed. Dr. Robert Huber and other researchers ...
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    12. Feature Of The Week 11/29/09: Optical Coherence Tomography Imaging of healthy skin, actinic skin and NMSC lesions

      Feature Of The Week 11/29/09: Optical Coherence Tomography Imaging of healthy skin, actinic skin and NMSC lesions
      Feature Of The Week 11/29/09: Optical coherence tomography applications in dermatology have faced somewhat of a challenge since, from some perspectives, skin was designed to keep light out. Skin cancer is a common form of cancer and although it is not in the top ten cancer killers, there are a large amount of resources being devoted to investigating suspicious liaisons and pathologies. For example, more than 1 million cases of non-melanoma skin cancer are diagnosed yearly in the United States. Melanoma, the most serious type of skin cancer, will account for about 70,000 cases of skin cancer ...
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    13. Michelson Diagnostics Wins Grant for Miniature OCT Probe Development

      Michelson Diagnostics Wins Grant for Miniature OCT Probe Development
      Michelson Diagnostics Ltd , the London, UK based developer and manufacturer of Optical Coherence Tomography (OCT) products, has won a £25,000 grant from the UK Government’s Technology Strategy Board (TSB). The grant is for a study into the feasibility of highly miniaturised OCT probes for cancer diagnoses. According to TSB data, seven hundred applications for funding were received, and Michelson Diagnostics application was one of just sixty-nine to be funded. Jon Holmes, CEO of Michelson Diagnostics, explained that the funded project will help Michelson determine which technologies to use in the development of practical rigid and/or flexible OCT ...
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    14. Feature Of The Week 11/22/09: Development of Optical Coherence Tomography Point-Spread Function Test Artifacts

      Feature Of The Week 11/22/09: Development of Optical Coherence Tomography Point-Spread Function Test Artifacts
      Feature Of The Week 11/22/09: The Biophotonics group of the UK National Physical Laboratory is working on methods and phantoms to help with the uptake of OCT technology in to the medical and other industrial sectors. They are looking at the requirements for consistent and robust characterization methods to determine the fundamental system performance of OCT systems. An important baseline metric in this respect is the system 3D point-spread function (PSF) that ultimately limits the optical resolution of an instrument. Conventionally the lateral and axial resolutions can be determined independently for instance using reflective interfaces or optical test-charts ...
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    15. Feature Of The Week 11/15/09: A Comparison between Optical Coherence Tomography and Histology of Laryngeal Epithelial Thickness

      Feature Of The Week 11/15/09: A Comparison between Optical Coherence Tomography and Histology of Laryngeal Epithelial Thickness
      Feature Of The Week 11/15/09: While applications of optical coherence tomography in ophthalmology and cardiology have very successfully transitioned from the research world to the commercial world many other fields have lagged behind. One such area is the field of Otolaryngology. While much of the technology developed in both the academic and commercial worlds is directly applicable to applications in otolaryngology there remain some unique features such as probe design and a need for additional clinical data to determine where OCT will be most beneficial. Numerous researchers around the world are working in this field. Researchers from the ...
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    16. Michelson Diagnostics Enters Into Exclusive Distribution Contract with Integral Corporation in Japan

      Michelson Diagnostics Enters Into Exclusive Distribution Contract with Integral Corporation in Japan
      (Orpington, UK) November 12, 2009 – Michelson Diagnostics has appointed Integral Corporation, a distributor of analytical equipment to the healthcare and cosmetics industry, as exclusive distributor for its VivoSight scanner in Japan. Michelson Diagnostics is a leading innovator in Multi-Beam Optical Coherence Tomography (OCT) products for scientific research and healthcare imaging. Under the terms of the agreement Integral Corporation will exclusively market and sell the VivoSight scanner for non-clinical use in cosmetic research settings. Integral has also purchased a VivoSight system for use in customer demonstrations that will begin in November. The agreement is the latest milestone Michelson Diagnostics has achieved ...
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    17. Feature Of The Week 11/08/09: Application of wavelet analysis in optical coherence

      Feature Of The Week 11/08/09: Application of wavelet analysis in optical coherence
      Feature Of The Week 11/08/09: Optical Coherence Tomography (OCT) is modern optical diagnostic technique, which is well suited for non-invasive imaging of the interior structures of dense media from a range of composite materials to biological tissues. Since OCT is known for being able to reject multiple scattering, it has been used successfully to image low scattering samples such as retina to considerably scattering samples such as biological tissues and synthetic scaffolds. However, with some highly scattering samples OCT struggles to cope with multiple scattering resulting in a rather poor quality of images. In order to improve the ...
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    18. Michelson Diagnostics Announces $1,500 Optical Coherence Tomography Student Travel Grant

      Michelson Diagnostics Announces $1,500 Optical Coherence Tomography Student Travel Grant
      Michelson Diagnostics, in partnership with OCT News, is pleased to announce a Michelson Optical Coherence Tomography student travel grant. The goal of this grant is to assist in the travel expenses of a student to attend the Photonics West Conference on January 23rd 2010. Click banner for details.
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    19. Michelson Diagnostics CEO Speaks at Royal Society of Medicine

      Michelson Diagnostics CEO Speaks at Royal Society of Medicine
      Jon Holmes, CEO of medical imaging firm Michelson Diagnostics Ltd (MDL), was invited to speak at the Royal Society of Medicine’s (RSM) first ‘Innovation Summit’, along with an impressive line-up of other world-leading medical innovators, who included Professor Laurent Lantieri, the pioneering face-transplant surgeon, and Dr Okarma, CEO of Geron, the US company leading the treatment of spinal cord injury with stem cell therapies. He presented to a packed audience of around 300 RSM Fellows and Members and described how MDL’s revolutionary new laser-based medical imaging technology could radically improve cancer diagnostics, by reducing the need for painful ...
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    20. Feature Of The Week 11/1/09: Dual-Fiber Stretcher as a Tunable Dispersion Compensator for an All-Fiber OCT Systems

      Feature Of The Week 11/1/09: Dual-Fiber Stretcher as a Tunable Dispersion Compensator for an All-Fiber OCT Systems
      Feature Of The Week 11/1/09: Over the past decade, OCT has been implemented with widely different geometries, including both free-space and fiber components. Fiber-based OCT systems are advantageous in terms of being low-cost, lightweight, stable, compact and portable. Most fiber systems still rely, however, on some free-space components, most notably in the optical delay line. The challenge here is that optical fibers often introduce a significant chromatic dispersion mismatch between the two arms of the interferometer, which unless properly compensated broadens the point-spread function (PSF) and degrades the axial resolution. Dispersion can in principle be canceled by adjusting ...
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    21. Feature Of The Week 10/25/09: Monitoring of Molecular Permeability in Tissues Using Optical Coherence Tomography

      Feature Of The Week 10/25/09: Monitoring of Molecular Permeability in Tissues Using Optical Coherence Tomography
      Feature Of The Week 10/25/09: Researchers at the Biomedical Optics Laboratory at the University of Houston led by Dr. Kirill Larin, and the Research Educational Institute of Optics and Biophotonics at Saratov State University, led by Dr. Valery Tuchin, have been doing pioneering work in Optical Coherence Tomography for well over a decade. Recent work has included monitoring of molecular permeability in tissue using OCT. The ability to image, monitor, and assess molecular transport in epithelial tissues noninvasively is an indispensible facet for a diverse range of biomedical applications. Topical drug delivery through epithelial tissues, such as skin ...
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    22. Should OCT News take banner advertising and blundle all proceeds for student travel grant? Vote on OCT News home page?

      Should OCT News take banner advertising and blundle all proceeds for student travel grant? Vote on OCT News home page?
      OCT News has been offered to have banner advertising several times. OCT News will remain a not-for-profit site. However the questions arises as to whether OCT News should take banner advertising and bundle all the proceeds for student travel grant. The grant would be awarded based on a future sponsor and maybe user voting perhaps based on some recent work or a submitted image or video. Let us know your thoughts by using the vote widget on home page. Also feel free to share your comments using the "comment block" below or send private information using the "Submit Information" or ...
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    23. Weekday and Weekly OCT News Newsletter Configuration Options.

      Weekday and Weekly OCT News Newsletter Configuration Options.
      Dear OCT News Subscriber Recently there was a survey on OCT News asking subscribers to see if they preferred an automated newsletter once per week, three days per week, five days per week, or seven days per week. The most popular answer was once per week. But the other categories had a significant share of the voting. OCT News now has two newsletter options. You can pick once per week or five days per week. By default all subscribers are currently set to once per week. If you are currently a subscriber you can keep this as a default or ...
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    24. Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement

      Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement
      Case Western Reserve University, University Hospitals Case Medical Center and Bioptigen Establish Exclusive Licensing Agreement Technology Helps Doctors and Researchers Diagnose and Seek Cures for Eye Diseases. CLEVELAND and RESEARCH TRIANGLE PARK, N.C. – Case Western Reserve University and University Hospitals Case Medical Center have granted to Bioptigen, of Research Triangle Park, N.C ., an exclusive intellectual property licensing agreement for Fourier domain optical coherence tomography (FDOCT), an imaging technology developed from research at the university’s Department of Biomedical Engineering. Advances in functional FDOCT are expected to enhance the early diagnosis and treatment of eye diseases, most notably diabetic ...
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