1. Optical Coherence Tomography News

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    1. University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effects of Poly-Drug Exposure of Fetal Brain Development

      University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effects of Poly-Drug Exposure of Fetal Brain Development

      University of Houston Receives 2019 NIH Grant for $345,824 for Optical Coherence Tomography to Study Effects of Poly-Drug Exposure of Fetal Brain Development. The principal investigator is Kirill Larin. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The overall objective of this study is to develop an optical coherence tomography (OCT) based high- resolution mouse embryonic brain imaging and analysis approach, and to use this method in correlation with molecular analysis to understand the interplay between ethanol (EtOH) and nicotine (NIC) effects on embryonic brain development. Maternal exposures to these ...

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    2. MGH Receives NIH Grant for Unique Value of Real-TIme Shear Stress to Enhance Coronary Disease Management.

      MGH Receives NIH Grant for Unique Value of Real-TIme Shear Stress to Enhance Coronary Disease Management.

      Massachusetts General Hospital Receives a 2019 NIH Grant for $729,778 for Unique Value of Real-TIme Shear Stress to Enhance Coronary Disease Management. The principal investigator is Guillermo Tearney. The program began in 2018 and ends in 2020. Below is a summary of the proposed work. Management of CAD is hindered by our inability to investigate fundamental pathobiologic processes that lead to individual coronary plaque progression, destabilization, and adverse clinical events. A critical mechanism responsible for plaque behavior is local endothelial shear stress (ESS), the frictional force of blood flowing across the endothelium, which is governed by the artery’s ...

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    3. MEEI Receives NIH Grant for Measuring and Modeling The Cochlear Motions that Drive The Inner and Outer Hair Cells and Produce Otoacoustic Emissions

      MEEI Receives NIH Grant for Measuring and Modeling The Cochlear Motions that Drive The Inner and Outer Hair Cells and Produce Otoacoustic Emissions

      Massachusetts Eye and Ear Infirmary Receives a 2019 NIH Grant for $540,156 for Measuring and Modeling The Cochlear Motions that Drive The Inner and Outer Hair Cells and Produce Otoacoustic Emissions. The principal investigator is Sunil Puria. The program began in 2007 and ends in 2022. Below is a summary of the propose work. Our knowledge of cochlear mechanics is currently undergoing a revolution. While the basilar membrane (BM) has long been considered the principal structure in cochlear motion, new techniques such as optical coherence tomography (OCT) have instead revealed not only that the reticular lamina (RL) moves in ...

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    4. Insight LiDAR Announces FMCW LiDAR Sensor for Autonomous Vehicle Market

      Insight LiDAR Announces FMCW LiDAR Sensor for Autonomous Vehicle Market

      Insight LiDAR today announced the development of Digital Coherent LiDAR, a chip-scale, long-range LiDAR sensor targeted at the emerging autonomous vehicle market. Insight’s Digital Coherent LiDAR is based on Frequency Modulated Continuous Wave (FMCW) technology offering a number of unique advantages over the current generation of Time-of-Flight (ToF) LiDAR sensors. Insight LiDAR is a spinout of Insight Photonic Solutions, a leader in the design and manufacture of highly-linear, swept-wavelength laser sources for imaging and sensing applications. Autonomous vehicles require a variety of sensors to interpret the world around them and to make proper, timely decisions. While ninety-three percent of ...

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    5. Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success

      Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success

      On December 14 and 15 2018, over 1400 ophthalmologists participated in Rome at tha most important meeting on OCT and OCT Angiography. the 6th international meeting on OCT Angiography, advances in OCT . The organizer, Dr Lumbroso has, since he started to organize these meetings, a well-defined objective: informing ophthalmologist in any country on the new clinical possibilities of Ocular imaging. The policy is to invite the best speakers in the world to teach basics and new developments to eager young ophthalmologists. The conference and talks by prominent specialists confirmed that OCTA opens new horizons and conveys new points of view ...

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    6. System Engineer / Senior System Engineer Opening at NinePoint Medical

      System Engineer / Senior System Engineer Opening at NinePoint Medical

      The Company: NinePoint Medical is a fast-paced medical device start-up based out of Bedford MA. With our recent strategic investment from Merit Medical, we are expanding our product development team. We develop, manufacture and commercialize cutting-edge medical imaging products with a big vision to detect, diagnose, and treat cancer before it becomes cancer. Today’s standard of care for diagnosis of disease relies on obtaining a tissue sample and performing costly processing and expert review of tissue sections. Using breakthrough optical imaging technology along with advanced machine learning algorithms, NinePoint Medical will provide treating physicians with real-time diagnostic capability, thus ...

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    7. Anzu Partners Completes Sale of Axsun Technologies to Excelitas Technologies

      Anzu Partners Completes Sale of Axsun Technologies to Excelitas Technologies

      Anzu Partners, a venture capital and private equity firm that invests in breakthrough industrial technologies, today announced that it has completed the sale transaction of Axsun Technologies to Excelitas Technologies Corp. The terms of the deal were not disclosed. Axsun Technologies is a leading developer and supplier of MEMS-based optical engines for medical imaging, industrial spectroscopy, and optical telecommunications. Axsun's optical engines enable many of the worlds leading optical coherence tomography (OCT) imaging systems used by opthalmologists, cardiologists, and other medical specialists. In recent years, Axsun has shipped more than 15,000 devices for these applications. Anzu Partners acquired ...

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    8. Postdoc Position at Vanderbilt University

      Postdoc Position at Vanderbilt University

      Description: The Bowden Laboratory for Biomedical Optics (https://lab.vanderbilt.edu/bowdenlab), as part of the Department of Biomedical Engineering and the Vanderbilt Biophotonics Center, develops optical imaging and sensing technologies for clinical and basic science applications, with additional interest in the development of low-cost and portable technologies for low-resource environments. We seek a new postdoc with expertise in programming and computer vision and an interest in biomedical applications to join our lab for an exciting project to poised to make a major impact in the medical fields of urology and gastroenterology. The proposed project builds on previous work from ...

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    9. Introducing the role of OCT and OCTA in neurology and neurophthalmology

      Introducing the role of OCT and OCTA in neurology and neurophthalmology

      On the 8th December 2018 over 350 ophthalmologists and neurologists participated in Bucharest at an intensive neurophthalmology course by dr.Catalina Dumitrescu and the Royal Club of Romanian Doctors with the purpose to update the information in this subspeciality, strengthen the relationship between the ophthalmologist and the neurologist and present the importance of OCT and OCTA in both neurology and neurophthalmology. We were honored by the presence of most outstanding neurologists: Prof.Dr. Ovidiu Bajenaru -member of romanian academy, Conf.Dr.Sorin Tuta - VP Romanian Stroke Society, from Paris international renown lecturer Prof.Dr.Mihaela Bustuchina, two of the most ...

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    10. PhD Opening in Applied Optics at University of Kent

      PhD Opening in Applied Optics at University of Kent

      Project Description A PhD position is available in the field of Lasers for Biomedical Optics. This project is in competition with other projects offered by the School of Physical Sciences for one of a number of Vice Chancellor’s PhD Studentships. The aim of the project is to devise the next generation of lasers for optical coherence tomography (OCT). Time stretch technology consists in using an ultrashort, ultrawide bandwidth laser that is stretched in a dispersing element. Using the concept of time stretch, over tens of MHz tuning rate becomes possible. Such lasers can drive the future OCT systems that ...

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    11. PhD Opening in Fibre-Based Holographic Imaging at University of Kent

      PhD Opening in Fibre-Based Holographic Imaging at University of Kent

      Project Description A PhD position is available in the field of Biophotonics. This project is in competition with other projects offered by the School of Physical Sciences for one of a number of EPSRC Doctoral Training Partnership Studentships. The aim of this project is to investigate the transmission of high resolution optical phase information over optical fibres using digital holography. Fibre-based microscopy has a range of applications in biosciences and medicine, including as a real-time, endoscopic alternative to conventional histology. While intensity-based imaging via fibre bundles is well-established, recovery of phase information is far more challenging and will require use ...

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    12. PhD Opening in Optical Coherence Tomography at University of Kent

      PhD Opening in Optical Coherence Tomography at University of Kent

      Project Description A PhD position is available in the field of Biophotonics. This project is in competition with other projects offered by the School of Physical Sciences for one of a number of EPSRC Doctoral Training Partnership Studentships. The aim of this project is to advance the technology of optical coherence tomography (OCT). OCT has a range of applications in medical imaging and the project can focus on one of the areas of rapid development such as Master Slave and Down-conversion OCT methods, prototyping OCT assemblies, or advancing the technology of OCT components such as the optical source or ultra ...

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    13. Avinger Announces Preliminary Analysis of Results from SCAN Clinical Study

      Avinger Announces Preliminary Analysis of Results from SCAN Clinical Study

      Avinger, Inc. (Nasdaq: AVGR), a leading developer of innovative treatments for peripheral artery disease (PAD), today announced the release of the preliminary analysis of results from its SCAN clinical study, a post-market study comparing optical coherence tomography (OCT) with intravascular ultrasound (IVUS) as a diagnostic imaging tool in the peripheral arteries. Initial analysis of the SCAN data indicated that OCT imaging with Avinger’s Pantheris System showed statistical superiority or equivalence to IVUS on all parameters evaluated. Avinger had previously announced completion of enrollment in the SCAN study in August 2018. During the study, 120 OCT and IVUS matched images ...

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      Mentions: FDA Avinger
    14. Notal Vision Engages Wasatch Photonics Bringing AI-Enabled Home-Based Optical Coherence Tomography Closer to Market

      Notal Vision Engages Wasatch Photonics Bringing AI-Enabled Home-Based Optical Coherence Tomography Closer to Market

      First U.S. clinical trial initiated with patient-operated home OCT device for monitoring patients diagnosed with exudative age-related macular degeneration (eAMD) Notal Vision, Inc., (“Notal”) a privately-held ophthalmic diagnostic services company, focused on advancing eye care by extending ophthalmic disease management from the clinic to the home, has announced the achievement of a significant milestone in its plan to develop and commercialize a home-based, patient-operated, spectral-domain optical coherence tomography (SD-OCT) system. The first targeted application of the Notal Home OCT is to monitor exudative (wet) age-related macular degeneration (eAMD) patients between scheduled, standard-of-care examinations by their treating retinal specialist. Notal ...

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    15. Axsun Technologies Announces Definitive Agreement to be acquired by Excelitas Technologies

      Axsun Technologies Announces Definitive Agreement to be acquired by Excelitas Technologies

      Axsun Technologies Inc., an Anzu Partners portfolio company, today announced that it has signed a definitive agreement to be acquired by Excelitas Technologies ® Corp., a global technology leader focused on delivering innovative, customized photonic solutions. The terms of the agreement are not being disclosed and the transaction is expected to close in early 2019. Jonathan Hartmann , CEO of Axsun, commented, "This is an outstanding opportunity for Axsun, our customers, and our employees as we continue to expand our product line and develop new markets together with Excelitas." "Our partnership with Anzu Partners has been outstanding, and we are grateful for ...

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    16. Excelitas Technologies Announces Agreement to Acquire Axsun Technologies

      Excelitas Technologies Announces Agreement to Acquire Axsun Technologies

      Excelitas expands portfolio of high performance photonics solutions serving the Medical and Industrial markets. W Excelitas Technologies ® Corp., a global technology leader focused on delivering innovative, customized photonic solutions, today announced that it has signed a definitive agreement to acquire Axsun Technologies (Billerica, MA USA). Axsun is a privately-held company specializing in the development and production of innovative, MEMS-based light engines for high performance medical imaging and industrial spectroscopy applications. Terms of the agreement are not being disclosed and the transaction is expected to Close in early 2019. F or more information on Excelitas, visit www.excelitas.com. About Excelitas ...

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    17. Moody's says Excelitas' proposed $80 million first lien term loan facility to acquire Axsun is a moderate credit negative; ratings unaffected

      Moody's says Excelitas' proposed $80 million first lien term loan facility to acquire Axsun is a moderate credit negative; ratings unaffected

      Moody's Investors Service ("Moody's") says EXC Holdings III Corp.'s (dba Excelitas) proposed $80 million incremental first lien term loan facility to fund the acquisition of Axsun is a modest credit negative, but it does not impact the company's B3 Corporate Family Ratings or stable rating outlook. Following the add-on, the USD denominated first lien term loan will increase to $685 million from $605 million ($681 million outstanding proforma at September 30, 2018). The $80 million proceeds along with $1.2 million of cash on hand will be used to fund the acquisition and approximately $5 million ...

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    18. Eunice Kennedy Shriver National Institute of Child Health & Human Development receives a NIH Grant for Quantitative Biophontonics for Tissue Characterization and Function

      Eunice Kennedy Shriver National Institute of Child Health & Human Development receives a NIH Grant for Quantitative Biophontonics for Tissue Characterization and Function

      Eunice Kennedy Shriver National Institute of Child Health & Human Development receives a 2018 NIH Grant for $741,019 for Quantitative Biophontonics for Tissue Characterization and Function. The principal investigator is Amir Gandjbakache. Below is a summary of the proposed work. Monitoring the placenta oxygenation is critical to ensure a healthy pregnancy outcome. Abnormalities in placental oxygenation has been associated with preeclampsia and intrauterine growth restriction, fetal hypoxia, asphyxia, and cerebral palsy. Currently, there are no patient-friendly devices to measure the oxygenation of the anterior placenta. Therefore, it is crucial to have a quantitative understanding of placental oxygenation. Functional Near Infrared ...

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    19. Opening for Technology Director – Core Products at Volk Optical Inc.

      Opening for Technology Director – Core Products at Volk Optical Inc.

      Position Summary The Technology Director role presents an exciting opportunity to lead and mentor a highly talented, dynamic and motivated team of engineers working on sustaining, enhancing and developing of currently marketed and new core products including diagnostic, laser and surgical lenses, surgical systems and marketed diagnostic imaging devices. The Product Development team at Volk embraces a culture of collaborative teamwork, impactful & customer-centric innovation, free exchange of ideas, fast-paced development, entrepreneurial mindset and can-do attitude. The ideal candidate will be a hands-on leader with a strong technical background and track record of developing new medical device products. The Director will ...

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      Mentions: Utkarsh Sharma
    20. Avinger Announces Commercial Launch in Australia

      Avinger Announces Commercial Launch in Australia

      Avinger, Inc. ( NASDAQ: AVGR ), a commercial-stage medical device company that designs and develops the first-ever image-guided, catheter-based system that diagnoses and treats patients with peripheral artery disease (PAD), today announced the commercial launch of its Pantheris image-guided atherectomy system in Australia. Avinger recently completed an exclusive distribution agreement with Diverse Devices Pty Ltd. for the sales and marketing of Avinger’s proprietary Lumivascular products in Australia. In addition, the Company announced it has received notice from Australia’s Therapeutic Goods Administration (TGA) that the Pantheris image-guided atherectomy system has been included on the Australian Register of Therapeutic Goods, which permits ...

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      Mentions: Avinger
    21. Notal Vision Announces FDA Grants Breakthrough Device Designation for Pioneering Patient-Operated Home Optical Coherence Tomography (OCT) System

      Notal Vision Announces FDA Grants Breakthrough Device Designation for Pioneering Patient-Operated Home Optical Coherence Tomography (OCT) System

      Notal Vision, Ltd., ("Notal") a privately-held ophthalmic diagnostic services company, focused on advancing eye care by extending ophthalmic disease management from the clinic to the home, has announced the U.S. Food and Drug Administration (FDA) granted the Notal Vision Home-based Optical Coherence Tomography (OCT) System with "Breakthrough Device" designation for the agreed upon indications for use. This designation indicates that FDA intends to provide interactive and timely communication with the sponsor during device development and throughout the review process for various types of premarket submissions. FDA's Breakthrough Devices Program was established in late 2016 to help patients gain ...

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    22. Michelson Diagnostics: Imaging Reveals Changes in Blood Vessel Growth in Deadly Melanoma Skin Cance

      Michelson Diagnostics: Imaging Reveals Changes in Blood Vessel Growth in Deadly Melanoma Skin Cance

      A new clinical study has shown that Dynamic Optical Coherence Tomography imaging of melanomas (D-OCT) reveals changes to the blood vessels that correlate with the depth of invasion of the melanoma. Researchers believe this could lead to a new faster method of rapidly assessing how dangerous a given melanoma is. A more rapid assessment of the risk would potentially allow patients with more serious invasive disease access to the right treatment more directly, doing away with delays inherent in the traditional diagnosis. The technique may also lead to reducing the number of patients with less aggressive tumours receiving sentinel lymph ...

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    23. Mirrorcle laser-cuts ribbon on cleanroom facility for volume MEMS mirror

      Mirrorcle laser-cuts ribbon on cleanroom facility for volume MEMS mirror

      In a ribbon cutting ceremony Mirrorcle Technologies inaugurated its new cleanroom space at the company’s Richmond, CA headquarters. Reflecting the company’s core competency of reliable optical beam-steering, the ribbon was cut by one of company’s latest products – a laser beam Scan Module which features a powerful 1W, blue (450nm) laser that was developed for the emerging dynamic solid-state lighting (phosphor lighting) market. As the company’s founder and CEO, Dr. Veljko Milanovic, dragged his finger on a tablet controlling the battery-powered Scan Module via Bluetooth, the laser beam, which was steered by the company’s 1.2mm ...

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    24. Postdoctoral Research Fellowship (In Vivo Microscopy) Wellman Center for Photomedicine

      Postdoctoral Research Fellowship (In Vivo Microscopy) Wellman Center for Photomedicine

      A Postdoctoral research fellowship in the area of In Vivo Microscopy is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow at Harvard Medical School. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new in vivo microscopy technologies with applications in basic and clinical research. The fellowship will focus on the development and clinical application of advanced in vivo microscopy imaging ...

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