1. Optical Coherence Tomography News

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    1. Feature Of The Week 9/20/09: Very late thrombosis of drug-eluding stent: Insights from Optical Coherence Tomography.

      Feature Of The Week 9/20/09: Very late thrombosis of drug-eluding stent: Insights from Optical Coherence Tomography.
      Feature Of The Week 9/20/09: Intracoronary Optical Coherence Tomography (OCT) has been recently introduced into the armamentarium of the interventional cardiologist. This technique offers an ultrahigh image resolution that allows detailed characterization of coronary atherosclerotic plaques, including lipid-rich plaques with a thin fibrous cap, called vulnerable plaques. Those plaques are the most frequent cause of acute coronary syndromes due to rupture of the fibrous cap and thrombosis. Intracoronary OCT is also a very useful tool to guide ICP procedures and to evaluate the vascular response after implantation of stents (neointimal coverage of the struts, vessel remodeling, reestenosis...) The ...
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    2. Feature Of The Week 9/13/09: In vivo imaging of human labial glands using advanced Optical Coherence Tomography

      Feature Of The Week 9/13/09: In vivo imaging of human labial glands using advanced Optical Coherence Tomography
      Feature Of The Week 9/13/09: Optical coherence tomography (OCT) has emerged as a high-resolution noninvasive clinical imaging application. Conventionally, minor salivary gland biopsy has been considered to be the cornerstone of the diagnosis of Sjögren syndrome. However, a minor salivary gland biopsy is an invasive examination that may cause inconvenience and a risk of complications to the patient. The purpose of this study was to show OCT images of human labial glands obtained using a swept-source (SS) OCT system. Labial gland OCT imaging was carried out using our new SS-OCT system for 5 healthy volunteers Using a hand-held ...
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    3. Feature Of The Week 9/6/09: Automated Quantification of Microstructural Dimensions of the Human Kidney using Optical Coherence Tomography

      Feature Of The Week 9/6/09: Automated Quantification of Microstructural Dimensions of the Human Kidney using Optical Coherence Tomography
      Feature Of The Week 9/6/09: Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can non-invasively provide cross-sectional, high-resolution images of tissue morphology in situ and in real-time. Recent development in high-speed OCT enables the acquisition of a large amount of three-dimensional image d
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    4. MICHELSON DIAGNOSTICS’ CEO VISITS NO.10 DOWNING STREET

      MICHELSON DIAGNOSTICS’ CEO VISITS NO.10 DOWNING STREET
      Orpington, UK, July 29th, 2009: Jon Holmes, CEO of Michelson Diagnostics Limited (MDL), the UK manufacturer of Multi-Beam Optical Coherence Tomography (OCT) scanners, was recently invited by the UK’s Prime Minister, Gordon Brown, to a reception for Britain’s entrepreneurs at No.10 Downing Street. We are very proud that Jon Holmes’ and Michelson Diagnostics’ achievements have been recognised in this way, and we are extremely pleased that the potential of OCT imaging to transform healthcare has been recognised at the highest levels of UK government. The reception, held on 22nd June 2009, was described by the Department of ...
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    5. Skin Cancer Trials of Michelson Diagnostics’ VivoSight OCT Probe commence

      Skin Cancer Trials of Michelson Diagnostics’ VivoSight OCT Probe commence
      Orpington, UK, July 29th, 2009: In-vivo trials of the Michelson Diagnostics’ VivoSight Multi-beam Optical Coherence Tomography (OCT) probe have begun. The trial, which is a collaboration between Michelson Diagnostics and Ludwig Maximilians University of Munich, will assess the capability of the pr
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    6. Feature Of The Week 7/26/09: Analyzing absorption and scattering spectra of micro-scale structures with spectroscopic optical coherence tomography

      Feature Of The Week 7/26/09: Analyzing absorption and scattering spectra of micro-scale structures with spectroscopic optical coherence tomography
      Feature Of The Week 7/26/09: Empowered by spatially resolved spectra, spectroscopic optical coherence tomography (SOCT) has drawn significant research attention. In particular, recent development of high resolution SOCT system intrigues great interest on the investigations of micro-scale structures,
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    7. Miniature Non-MEMS Scanner for Small Size Imaging Systems

      Miniature Non-MEMS Scanner for Small Size Imaging Systems
      The SMALLEST non-MEMS Resonant Scanner currently on the market was developed by Electro-Optical Products Corp. It is a miniature electromagnetically driven moving mirror device (0.9 ´ 0.5 x 0.4 inches), which deflects a light beam with a continuous sinusoidal motion.   The SC-3’s mirro
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    8. Michelson Diagnostics delivers First Sale in the USA

      Michelson Diagnostics delivers First Sale in the USA
      Orpington, UK, July 14th, 2009: Michelson Diagnostics Limited (MDL), the UK manufacturer of Multi-Beam Optical Coherence Tomography (OCT) scanners, is pleased to announce delivery of a unit to its first US customer. The EX1301 OCT Microscope is being used by the Center for Pharmacogenomics, Washingt
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    9. Feature Of The Week 7/11/09: High temporal resolution OCT using image-based retrospective gating

      Feature Of The Week 7/11/09: High temporal resolution OCT using image-based retrospective gating
      Feature Of The Week: 7/11/09: Studying abnormalities during heart development in the embryo is crucial for the understanding of congenital heart disease. Our group has been developing specialized OCT-based instruments and software and applying them to the study of the developing heart in avian and mouse models [1-5]. The developing morphology is of interest, but even more interesting is the development of cardiac function, the ability of the heart to contract and pump blood. Several groups have shown that mechanical forces influence the morphogenesis of the developing heart [6-9].
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    10. Michelson Diagnostics announces launch of VivoSight Multi-Beam OCT scanner

      Michelson Diagnostics announces launch of VivoSight Multi-Beam OCT scanner
      London, 8 July 2009: Michelson Diagnostics Limited (MDL), the UK manufacturer of Multi-Beam Optical Coherence Tomography (OCT) scanners, is pleased to formally announce the launch of its ‘VivoSight’ Multi-Beam OCT scanner. The scanner uses the high resolution capability of the company’s propri
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    11. Feature Of The Week 7/5/09: Single-body lensed-fiber scanning probe actuated by magnetic force for optical imaging

      Feature Of The Week 7/5/09: Single-body lensed-fiber scanning probe actuated by magnetic force for optical imaging
      Feature Of The Week: 7/5/09: In recent years, hand-held and endoscopic optical coherence tomography (OCT) has been investigated for a variety of clinical and therapeutic applications. As critical factors affecting the OCT performance, compactness and scanning speed of the sample arm of an OCT system have been widely recognized. Therefore, many scanning schemes have been investigated such as piezoelectric, rotational-micro-electro-mechanical-system (MEMS), electrostatic, and bimorph scanners. However, the piezoelectric scanner required high driving voltage, the MEMS scanner needs a complicated fabrication process, and the performance of the bimorph was material dependent and sensitive to external parameters, such as temperature ...
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    12. Feature Of The Week: 6/26/09: Fully Automatic Three-Dimensional (3D) Quantitative Analysis of Intracoronary Optical Coherence Tomography: Method and Validation

      Feature Of The Week: 6/26/09: Fully Automatic Three-Dimensional (3D) Quantitative Analysis of Intracoronary Optical Coherence Tomography: Method and Validation
      Feature Of The Week: 6/26/09: Optical Coherence Tomography continues to make tremendous progress in the diagnosis and treatment of coronary artery disease and second generation systems have accelerated that progress. The Thoraxcenter has been a leading organizations in this field as can be seen by clicking the Cardiology tag an scrolling down to "Organizations in the News". Described below is some recent work by Nico Bruining et al which discusses fully automatic three-dimensional quantitative analysis of intracoronary OCT.
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    13. Michelson Diagnostics Opens US Offices And Appoints US Business Development Manager

      Michelson Diagnostics Opens US Offices And Appoints US Business Development Manager
      Orpington, UK, June 23rd, 2009: Michelson Diagnostics Limited (MDL) announced today that it has opened a sales and support office in the USA. The office is located in Fuquay-Varina, (in the Research Triangle vicinity of Raleigh-Durham), North Carolina, and is headed by Kevin C. Oakley, Business Development Manager (US) for Michelson Diagnostics. The new office will act as a hub for growth of MDL’s business in the field of Optical Coherence Tomography (OCT) imaging, which has great applications potential in fields such as skin cancer diagnosis, genetics research and tissue engineering development. The company has no FDA-approved clinical products ...
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    14. Feature Of The Week 6/21/09: Laparoscopic optical coherence tomography imaging of human ovarian cancer

      Feature Of The Week 6/21/09: Laparoscopic optical coherence tomography imaging of human ovarian cancer
      Feature Of The Week 6/21/09: Ovarian cancer is the fourth leading cause of cancer-related death among women in the US, largely attributed to late detection due to unreliable symptomology and screening tools without adequate resolution and specificity. As a result, ovarian cancer is often diagnosed at advanced stages, after invasion of adjacent structures or metastasis to a distant site. Women with regional and distant disease have a 5-year survival rate of 71% and 30% (at best), respectively. If diagnosed at the localized stage, the 5-year survival rate is 92%; however, only about 19% of all cases are detected ...
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    15. Professor Fujimoto was presented with the Hounsfield Medal at Imperial College London

      Professor Fujimoto was presented with the Hounsfield Medal at Imperial College London
      The annual Hounsfield memorial lecture was instituted by the Imperial College London Imaging Sciences Centre to recognise the contribution of Sir Godfrey Hounsfield in the development of medical imaging systems. The lecture has been designed as an opportunity for a world leading researcher in imaging science to review the latest developments in imaging science. This is supported by a range of posters produced by imaging related research groups in Imperial which demonstrate the scope and depth of research going on at the College. The fifth lecture in the series was given on 8th June 2009 by Professor James Fujimoto from ...
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    16. Feature Of The Week 6/14/09: Assessing Sirolimus-Eluting Stent Implantation by Optical Coherence Tomography

      Feature Of The Week 6/14/09: Assessing Sirolimus-Eluting Stent Implantation by Optical Coherence Tomography
      Feature Of The Week 6/14/09: Heart disease is a leading cause of death in the industrialize world. Since the early 1990's when the Palmaz bare medal stent was introduced, stents have continued to play a major role in the treatment of heart disease. The stent market is over $5B and there is intense pressure to improve stent technology from both a healthcare and market share perspective. Optical Coherence Tomography is unique in its ability to provide critical information in assessing the impact, safety, and efficacy of stents. Some recent work by researchers at Kobe University and Stanford ...
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    17. Feature Of The Week 6/7/09: Optical micro-angiography: A label-free imaging technique to image blood perfusion within microcirculation tissue beds

      Feature Of The Week 6/7/09: Optical micro-angiography: A label-free imaging technique to image blood perfusion within microcirculation tissue beds
      Feature Of The Week 6/7/09: Researchers from the Biophotonics and Imaging Laboratory (BAIL) at Oregon Health & Science University (OHSU) have pioneered a new volumetric imaging modality, optical micro-angiography (OMAG) that is capable of imaging blood perfusion, down to capillary level resolution, within microcirculation tissue beds in vivo. Unlike Doppler OCT to image blood flow, OMAG explores implicitly the phase information embedded in the OCT spectral interferograms. By using heterodyne technology, OMAG method effectively separates the scattering signals caused by the moving scatters, for example moving blood cells, from the scattering signals backscattered by the static tissue background, i ...
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    18. Michelson Diagnostics continues Expansion with the Hire of a New Senior Imaging Scientist

      Michelson Diagnostics continues Expansion with the Hire of a New Senior Imaging Scientist
      Orpington, UK, June 1st, 2009: Michelson Diagnostics (MDL) is pleased to announce the appointment of Dr Florian Bazant-Hegemark as Senior Imaging Scientist. Dr Bazant-Hegemark, known as "Flo", has been working in optical coherence tomography (OCT) in his position as a Clinical Scientist in the biophotonics research group at Gloucestershire Royal Hospital NHS Foundation Trust where he co-authored a landmark article in the Biophotonics journal in 2007. "We are most fortunate that Flo has joined our company," said Jon Holmes, MDL’s CEO. "His practical experience will be invaluable to help customers use the problem-solving power of Multi-Beam OCT. The timing ...
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    19. Feature Of The Week 5/31/09: Evaluation of oral vascular anomalies using optical coherence tomography

      Feature Of The Week 5/31/09: Evaluation of oral vascular anomalies using optical coherence tomography
      Feature Of The Week 5/31/09: The continued technological and application progress in the field of Optical Coherence Tomography (OCT) is rapidly bringing to fruition the concept of an optical biopsy – the ability to non-invasively image in-situ tissue at a resolution approaching histopathology. There are numerous applications for an optical biopsy including in the oral vascular where researchers from the National Center for Geriatrics and Gerontology in Japan, Santec, and Tokyo Medical and Dental University have shown interesting results using a hand-held scanner. These slides present results from a recent study whose purpose was to present the first OCT ...
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    20. GE Healthcare and LightLab Imaging Inc. Collaborate on Cardiovascular Imaging

      GE Healthcare and LightLab Imaging Inc. Collaborate on Cardiovascular Imaging
      Barcelona, SPAIN and Westford, MA, USA; May 19, 2009: GE Healthcare, a global leader in healthcare solutions and LightLab Imaging Inc., a market leader in optical imaging, today announced a collaboration that enables improved workflow between GE Healthcare’s Innova® cardiovascular X-ray system and LightLab Imaging Inc.’s C7-XR™ Optical Coherence Tomography system. Both the C7-XR and Innova systems will be featured this week at the annual meeting of EuroPCR, the official congress of the EAPCI (European Association for Percutaneous Cardiovascular Interventions) in Barcelona, Spain. The LightLab C7-XR is available for purchase from LightLab in twenty countries in Europe, Asia ...
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    21. Feature Of The Week 5/24/09: Investigation of Oddi sphincter structure by optical coherence tomography in patients with biliary-type 1 dysfunction.

      Feature Of The Week 5/24/09: Investigation of Oddi sphincter structure by optical coherence tomography in patients with biliary-type 1 dysfunction.
      Feature Of The Week 5/24/09: Researchers from the Scientific Institute of San Raffaele, Azienda Ospedaliera San Paolo - University Hospital in Milan, and University of Milan have done leading research in the application of Optical Coherence Tomography to the area of gastroenterology and gastrointestinal endoscopy. These slide illustrate some of their recent work entitled "Investigation of Oddi Sphincter Structure by Optical Coherence Tomography in Patients with Biliary-Type 1 Dysfunction: A Pilot In Vivo Study". Type 1 sphincter of Oddi (SO) dysfunction is a clinical entity characterized by biliary-type pain, elevated liver biochemical tests, and common bile duct (CBD) dilatation ...
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