1. Optical Coherence Tomography News

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    1. Tomophase Receives Seventh Patent: Delivering Light via Optical Waveguide and Multiview Optical Probe Head

      Tomophase Receives Seventh Patent: Delivering Light via Optical Waveguide and Multiview Optical Probe Head
      BURLINGTON, Mass.--(BUSINESS WIRE)--Tomophase Corporation, a leading developer of non-invasive optical coherence tomography (OCT) tissue imaging devices, announced today that it has received notification of the issuance of its seventh patent: Delivering Light via Optical Waveguide and Multi-view Opt
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    2. Feature Of The Week 4/25/10: New Developments Intra-Coronary Optical Coherence Tomography

      Feature Of The Week 4/25/10: New Developments Intra-Coronary Optical Coherence Tomography
      Feature Of The Week 4/25/10: The development of sophisticated software imaging processing algorithms for Optical Coherence Tomography continues to be a hot area for both academic researchers and the OCT industry. Both the research community and the industrial sector see this as an opportunity for differentiation as the underlying hardware technology becomes more mature. In ophthalmology the level of imaging processing sophistication has reached impressive levels as a result of almost 20 years of commercial use and a boost from Fourier domain OCT detection techniques enabling faster imaging and larger data sets. Not far behind in OCT imaging ...
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    3. Research Associate or Research Fellow in Optical Coherence Tomography at Nottingham Trent University

      Research Associate or Research Fellow in Optical Coherence Tomography at Nottingham Trent University
      Research Associate or Research Fellow in Optical Coherence Tomography Nottingham Trent University - College of Science, School of Science and Technology The Next Generation of Optical Coherence Tomography (OCT) for Art Conservation - in situ non-invasive imaging of subsurface microstructure of objec
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    4. Feature Of The Week 4/11/10: Noninvasive Assessment of Healing of Bacteria Infected and Uninfected Wounds using Optical Coherence Tomography

      Feature Of The Week 4/11/10: Noninvasive Assessment of Healing of Bacteria Infected and Uninfected Wounds using Optical Coherence Tomography
      Feature Of The Week 4/11/10: Microbial infection is one of the major factors for the impairment of wound healing as the microbial toxins have a detrimental effect on collagen in the wounded tissue. Infected wounds can cause increased trauma, could severely compromise the overall health of an individual as well as increase the cost of treatment. To facilitate a faster healing of wounds it will be desirable if the signatures of microbial infection in wounds can be monitored non-invasively. OCT is an ideal non-invasive imaging technique for this purpose as it provides high-resolution cross-sectional images of tissues with ...
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    5. Feature Of The Week 4/4/10: Ce3+:YAG double-clad crystal fiber based optical coherence tomography on fish cornea

      Feature Of The Week 4/4/10: Ce3+:YAG double-clad crystal fiber based optical coherence tomography on fish cornea
      Feature Of The Week 4/4/10: With the tremendous success of optical coherence tomography (OCT) in recent years, high resolution and high image fidelity are getting more importance. So far, several approaches have been proposed to achieve high axial resolution, such as multiplexed superluminescent diode, femtosecond laser, continuum generation from photonic crystal fiber, and xenon illuminator. In general, these solutions are either have high cost, exhibit bumpy spectrum, or both. In contrast, spontaneous emission light can generate broadband and near-Gaussian spectrum, but the power level is often very weak. Using waveguide to collect the amplified spontaneous emission (ASE) can ...
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    6. The Embryonic Heart: Imaging Life as it Happens - University of Houston Professor Captures Video of Heart Before it Begins to Beat (Video Snippet)

      The Embryonic Heart: Imaging Life as it Happens - University of Houston Professor Captures Video of Heart Before it Begins to Beat (Video Snippet)
      Imagine being able to image life as it happens by capturing video of the embryonic heart before it begins beating. A professor at the University of Houston, in collaboration with scientists at Baylor College of Medicine, is doing just that. Kirill Larin, assistant professor of biomedical engineering in the Cullen College of Engineering at UH, and his colleagues in the Texas Medical Center are documenting the formation of the mammalian heart through a high-resolution, non-invasive imaging device, providing perhaps the best live imagery taken of the vital organ. “Everything we know about early development of the heart and formation of ...
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    7. Michelson Diagnostics Expands Sales and Customer Support Team

      Michelson Diagnostics Expands Sales and Customer Support Team
      (Orpington, UK) March 23, 2010 -- Michelson Diagnostics (MDL) the leading provider of clinical OCT imaging systems is pleased to announce the appointment of two new members to their sales team. Dr. David Heard has been appointed Sales Manager and will be responsible for developing worldwide sales for both clinical and non-clinical applications. Dr. Daniel Woods has joined as Senior Imaging Scientist and will provide additional technical expertise for customers in Medical and Biological fields.
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    8. Massachusetts General Hospital announces creation of international registry for coronary optical coherence tomography

      Massachusetts General Hospital announces creation of international registry for coronary optical coherence tomography
      Massachusetts General Hospital, together with a coalition of 20 international sites in five countries, announced the creation of the world’s largest registry of patients who have had optical coherence tomography (OCT) of the coronary arteries. OCT is an intravascular imaging technology that researchers hope will give doctors a better means to identify the dangerous vulnerable plaques that cause heart attacks and sudden cardiac death. When a vulnerable plaque in the coronary artery ruptures the result for the patient can be catastrophic. The ruptured plaques can block blood flow to the heart, and cardiologists predict they cause two-thirds to three-quarters ...
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    9. Feature Of The Week 3/21/10: An Update on Novel Non-Invasive Approaches for Periodontal Diagnosis

      Feature Of The Week 3/21/10: An Update on Novel Non-Invasive Approaches for Periodontal Diagnosis
      Feature Of The Week 3/21/10: Periodontitis is currently diagnosed almost entirely on the basis of its clinical manifestations: signs of gingival inflammation (e.g., redness and swelling), probing depth (PD), and level of periodontal attachment or amount of alveolar bone loss. In fact, alveolar bone and periodontal attachment loss represent the results of the destructive aspects of the host defense mechanisms responding to opportunistic infections by bacteria present in the gingival sulcus as well as the direct effects of virulence factors of periodontal pathogens. Alveolar bone and periodontal attachment loss cannot be used to predict the susceptibility to ...
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    10. Feature Of The Week 3/14/10: Multimodal Imaging with Integrated Photoacoustic Microscopy and Optical Coherence Tomography

      Feature Of The Week 3/14/10: Multimodal Imaging with Integrated Photoacoustic Microscopy and Optical Coherence Tomography
      Feature Of The Week 3/14/10: Photoacoustic Ophthalmoscopy (PAOM) is based on Laser-scanning Optical Resolution Photoacoustic Microscopy (LS-OR-PAM), which is a branch of photoacoustic microscopy (PAM). LS-OR-PAM was first developed with the collaboration of Dr. Hao Zhang's lab at University of Wisconsin-Milwaukee and Dr. Shuliang Jiao lab at University of Southern California. PAOM detects the photoacoustic signal induced by pulsed laser light shined onto the retina. By using a stationary ultrasonic transducer in contact with the eyelids and scanning only the laser light across the retina, PAOM provides volumetric imaging of the retinal micro-vasculature and retinal pigment epithelium ...
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    11. Feature Of The Week 3/7/10: OCT Guidance for Femtosecond Laser Treatment of Presbyopia

      Feature Of The Week 3/7/10: OCT Guidance for Femtosecond Laser Treatment of Presbyopia
      Feature Of The Week 3/7/10: Despite the clear and continually growing commercial success of Optical Coherence Tomography (OCT) in a wide range of clinical fields including ophthalmology, cardiology, and microscopy there remain few commercialized examples of OCT integrated with real-time surgical treatment procedures. However, those examples cannot be too far off based on some of the interesting advances in the OCT research world. One recent example was the demonstration of OCT guidance for femtosecond laser treatment of presbyopia which was demonstrated by The Biomedical Optics Department at the Laser Zentrum Hannover e.V. A short description and slide ...
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    12. Australia & New Zealand Optical Coherence Tomography Workshop May 7th, 2010

      Australia & New Zealand Optical Coherence Tomography Workshop May 7th, 2010
      “Welcome to the Inaugural Australia & New Zealand Optical Coherence Tomography Workshop. We have set out a program with an internationally recognized faculty to review the use of OCT and discuss its exciting role in Interventional Cardiology. Thank you for joining us”. Peter Barlis & Rob Whitbourn. Enquiries to info@anzoct.org or go to www.anzoct.org.
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    13. 1st Massachusetts General Hospital OCT Registry Symposium Scheduled for March 13, 2010

      1st Massachusetts General Hospital OCT Registry Symposium Scheduled for March 13, 2010
      The utilization of OCT has grown tremendously since the launch of the world’s first frequency domain OCT system (FD-OCT) from LightLab Imaging, Inc. in late 2009. Over 9,000 cases were performed last year, slightly less than the cumulative cases performed in the three years prior with the older Time Domain OCT which was much slower and harder to use. “OCT has come a long way". States Dr. Ik-Kyung Jang. "I have used the new system and it is really fast and easy to use. Because of its data acquisition speed no occlusion is required and the image quality ...
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    14. Cement not included – 10:1 return on investment from federal infrastructure investment in photonics

      Cement not included – 10:1 return on investment from federal infrastructure investment in photonics
      Responding to the credit crisis and resulting global recession, national governments around the world are furiously pumping cement-truck loads of money into infrastructure projects. Some of these economic stimulus initiatives will work, some will fail, and few will offer a specific Return On Investment (ROI). Roads, bridges buildings and last generation manufacturing jobs are important – and easy to justify in a political context. Yet building a next generation of successful “cement not included” innovation companies will in turn generate long-term jobs, exports, tax bases, and ultimately pay the tab on the short-term stimulus spends.
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    15. Michelson Diagnostics Reports First Quantitative Results on Cancer Diagnosis Using Multi-beam OCT imaging

      Michelson Diagnostics Reports First Quantitative Results on Cancer Diagnosis Using Multi-beam OCT imaging
      The first quantitative results from a study on the use of multi-beam OCT imaging for oral cancer diagnosis have been announced at the 2nd Scientific Meeting of the Head and Neck Optical Diagnostics Society (HNODS), held in San Francisco, 23-24 January, as part of SPIE Photonics West. The presenting authors, Professor Colin Hopper, Dr Waseem Jerjes, and Zaid Hamdoon of University College Hospital London, concluded from the study that multi-beam OCT imaging will be a very useful clinical diagnostic tool for early diagnosis of oral cancer, and for measurement of tumour resection margins in oral cancer. In the study, the ...
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    16. Feature Of The Week 2/28/10: Multichannel optical coherence tomography using a high-power telescope-less polygon-based swept laser in dual-amplifier configuration

      Feature Of The Week 2/28/10: Multichannel optical coherence tomography using a high-power telescope-less polygon-based swept laser in dual-amplifier configuration
      Feature Of The Week 2/28/10: Researchers at the University of Toronto, Ontario Cancer Institute and Ryerson University have been actively advancing Optical Coherence Tomography (OCT) in several areas, including application of Doppler OCT (DOCT) and advancing the underlying technology to expand and improve the applications and capability of this imaging modality. The group, led by Dr. Alex Vitkin and Dr. Victor Yang, has clinical experience in circulation imaging of the gastrointestinal tracts, the prostate, the colons, the lungs, and more. This group also developed a microvasculature imaging technique called speckle variance OCT (SV-OCT) that can capture, with high ...
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    17. Feature Of The Week 2/21/10: Measurements of Biomechanics by Dynamic Optical Coherence Elastography

      Feature Of The Week 2/21/10: Measurements of Biomechanics by Dynamic Optical Coherence Elastography
      Feature Of The Week 2/21/10: Optical coherence elastograhy (OCE) is a novel elastography technique that can measure tissue biomechanical properties using mechanical excitations and in vivo optical coherence tomography (OCT). This technique has great potential for detecting mechanical property changes in the tissue micro-structure, such as tumor invasion, due to its high resolution, high speed and non-invasive features. OCE techniques can be classified as static and dynamic depending on its mechanical excitation approaches. Static methods are commonly used in conventional OCE studies, and are based on cross-correlation algorithms1. We concentrated on dynamic OCE techniques in which the sample ...
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    18. Feature Of The Week 2/7/10: Manual-Scanning Optical Coherence Tomography (OCT) Probe Based on Position Tracking

      Feature Of The Week 2/7/10: Manual-Scanning Optical Coherence Tomography (OCT) Probe Based on Position Tracking
      Feature Of The Week 2/7/10: Optical Coherence Tomography (OCT) is now an important modality in the field of biomedical imaging for its high resolution and non-invasive nature. People have been developing OCT endoscopes to penetrate into deep biological tissues and extend the limited light penetration depth in near infrared wavelength region. Different ways of steering the probing beam have been developed over the years. As most of them need some form of mechanical actuation, they usually come with the associated cost of additional hardware that must be integrated onto the probes. An OCT probe that can be manually ...
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    19. Biomedical Optics Workshop at Boston University Photonics Center

      Biomedical Optics Workshop at Boston University Photonics Center
      The exponential growth of Biomedical Optics in the last decade, resulting from the application of maturing technologies in optical imaging, integrated optics, fiber optics, lasers, detectors, and nano-technology to the medical field, requires practicing professionals to become knowledgeable about a whole new generation of opto-electronic medical equipment. Due to the efforts of innovative researchers, a wide variety of advanced optical techniques have been developed (diffused optical imaging, multi-photon microscopy, optical tomography) for clinical monitoring of diseases in vivo and ex vivo, and pathogen detection. These techniques are becoming essential in Genomics, Proteomics, Biomedical diagnostics, and therapeutics to mention a few ...
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    20. Feature Of The Week 1/31/10: Mechanical Compression Effect in Optical Coherence Tomography Imaging of Biotissues

      Feature Of The Week 1/31/10: Mechanical Compression Effect in Optical Coherence Tomography Imaging of Biotissues
      Feature Of The Week 1/31/10: The majority of pathological processes in biotissues lead to their structural changes. The information about such changes is important for correct diagnostics and choice of proper treatment strategy. These changes can be detected using the optical coherence tomography (OCT). For application of OCT diagnostics in endoscopic studies the development of sufficient OCT-probes is required. However, the developed endoscopic OCT-probes are contact and their usage induces compression of the sample under study. Thus, the study of compression effect on the obtained OCT images of biotissues is of importance. In addition some pathological states could ...
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    21. LightLab Imaging Receives Prism Award

      LightLab Imaging Receives Prism Award
      Westford, MA, January 27, 2010 – LightLab Imaging Inc., the pioneer and leader in the development of Optical Coherence Tomography (OCT) for vascular and other imaging applications, today announced the receipt of the Prism Award for Photonics Innovation in the life sciences category. This award was presented by Laurin Publishing and SPIE during SPIE Photonics West on January 27, 2010 to honor photonics innovation. Awards were presented to nine other products in eight other categories. “It is an honor to be recognized by SPIE with this Prism Award.” said Joe Schmitt, Chief Technology Officer of LightLab Imaging. “This shows how the ...
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    22. Feature Of The Week 1/24/10: Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography

      Feature Of The Week 1/24/10: Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography
      Feature Of The Week 1/24/10: David Huang was one of the co-inventors of Optical Coherence Tomography and has continued to do pioneering research in OCT from his early days doing PhD work at the Massachusetts Institute of Technology to his current position as a professor of ophthalmology at the Keck School of Medicine at the University of Southern California. A topic recently studied by Dr. Huang and his collaborators is Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography. Glaucoma is diagnosed clinically by observing optic nerve cupping and visual field defects. Although histopathological ...
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    23. Feature Of The Week 1/17/10: Full-Field Optical Coherence Tomography for the Rapid Estimation of Epidermal Thickness

      Feature Of The Week 1/17/10: Full-Field Optical Coherence Tomography for the Rapid Estimation of Epidermal Thickness
      Feature Of The Week 1/17/10: A number of recent developments in non-invasive physiological monitoring of the human body have demonstrated a high potential for the use of such techniques in the in vivo estimation of various clinically relevant parameters such as haemoglobin content and its’ oxygen saturation, amount of glycated haemoglobin, alcohol, etc. One of the most promising of those parameters is the non-invasive estimation of tissue glucose concentration which can potentially bring a great relief for the patients with Diabetes Mellitus, for whom the tight glucose control is the major requirement for long term therapy. The majority ...
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    24. Announcement of Michelson-Diagnostics OCT-News Student Travel Grant Winner

      Announcement of Michelson-Diagnostics OCT-News Student Travel Grant Winner
      On November 4th OCT News in partnership with Michelson Diagnostics and funded by a generous donation from Michelson Diagnostics, announced a $1,500 student travel grant opportunity. We received numerous submissions all of which displayed outstanding work. The awards were ranked by OCT News, Michelson Diagnostics, and an independent 3rd party based on results, presentation, novelty, and potential utility. The final rankings of the top 3rd of the presentations were nearly identical and choosing a winner was difficult. The winner was Yan Wang for her submission on “Quantitative assessment of peripheral nerve damage using polarization-sensitive optical coherence tomography”. Ms. Wang ...
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