1. Optical Coherence Tomography News

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    1. Northwestern University Receives NIH Grant for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Optical Detection

      Northwestern University Receives NIH Grant for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Optical Detection

      Northwestern University Receives a 2021 NIH Grant for $507,515 for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Optical Detection. The principal investigator is Hao Zhang. Below is a summary of the proposed work. Our long-term goal is to develop new functional extensions of optical coherence tomography (vis-OCT) for clinical diagnosis and management of glaucoma. Glaucoma is characterized by a progressive loss of retinal ganglion cells (RGCs) and optic nerve defects and atrophy, afflicting more than 60 million people worldwide. It is often develops slowly with symptoms and damage that are not noticed at early stage. Caring for ...

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    2. Duke University Receives NIH Grant for Whole Eye Optical Coherence Tomography to Improve Eye Care

      Duke University Receives NIH Grant for Whole Eye Optical Coherence Tomography to Improve Eye Care

      Duke University Receives a 2021 NIH Grant for $370,832 for Whole Eye Optical Coherence Tomography to Improve Eye Care. The principal investigator is Anthony Kuo. Below is a summary of the proposed work. This research proposal from a multi-disciplinary team including ophthalmologists and biomedical engineers seeks to improve the imaging and characterization of posterior eye deformities such as in progressive or pathologic myopic and high intracranial pressure. The three-dimensional changes seen in the posterior eye with these diseases have usually been characterized using neuro-imaging. To make this assessment more available in the clinical ophthalmic setting, we will further develop ...

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    3. Research Associate in Biophotonics at University of Sheffield

      Research Associate in Biophotonics at University of Sheffield

      University of Sheffield - Faculty of Engineering: Department of Electronic and Electrical Engineering Location: Sheffield Salary: £31,866 to £40,322 Grade 7 annum Hours: Full Time Contract Type: Fixed-Term/Contract Placed On: 20th May 2021 Closes: 16th June 2021 Job Ref: UOS028559 Contract Type: Fixed term until for 36 months. As a Research Associate, you will work in the biophotonics group of Professor Stephen Matcher. Steve Matcher’s group has a strong international reputation in biophotonics, especially in the development and application of optical coherence tomography (OCT) techniques. We maintain active collaborative links within the university (for example, the Medical ...

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    4. Postdoctoral Research Associate GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign

      Postdoctoral Research Associate GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign

      The GlaxoSmithKline Center for Optical Molecular Imaging at the Beckman Institute for Advanced Science and Technology seeks a bright, energetic, and motivated candidate to fill a vacancy for a full-time Postdoctoral Research Associate in the area of image data analysis. The purpose of this position is to lead the analysis of image data from translational optical biomedical imaging systems. The successful candidate will need a solid and broad understanding of image analysis software as well as software development including high-level user interface requirements in a Windows environment, data file structure design, experience with data acquisition and control interfacing, high-volume real-time ...

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    5. Notal Vision raises up to $60 million to support development of its Home OCT technology and commercial growth of its ForeseeHome AMD Monitoring Program

      Notal Vision raises up to $60 million to support development of its Home OCT technology and commercial growth of its ForeseeHome AMD Monitoring Program

      Notal Vision, Inc., a privately held ophthalmic home monitoring services provider focused on early disease detection and treatment monitoring is pleased to announce the closing of a Series D financing co-led by Soleus Capital and the company’s majority shareholder Ganot Capital. Existing shareholders Elron and Evergreen contributed significantly to the round. The investment supports the commercial growth of the company’s current service, the ForeseeHome AMD Monitoring Program, as well as the go-to-market strategy for its Home OCT pipeline technology. “We believe the Home OCT device from Notal Vision has the potential to transform care for millions of patients ...

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      Mentions: Notal Vision
    6. Senior/Staff System Engineer Opening at Optovue

      Senior/Staff System Engineer Opening at Optovue

      Job Title: Senior/Staff Systems Engineer Date: June 1, 2021 Department: R&D Approved by: HR Dir. Reports to: Systems Engineering Manager Classification: Exempt Type of position: Full Time About us: Optovue, Inc. (Fremont, CA) is an ophthalmic device company dedicated to working with eye care professionals, doctors, and researchers to improve patient care through sustained technological innovation. Innovation is firmly entrenched in our DNA and we take pride in the fact that Optovue has pioneered disruptive medical imaging technologies including spectral-domain OCT and OCT Angiography that have been revolutionizing the field of Ophthalmology. We remain passionate about engineering and ...

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      Mentions: Optovue
    7. Massachusetts General Hospital Receives NIH Grant for Volumetric optical connectome microscopy of human cerebellar circuitry

      Massachusetts General Hospital Receives NIH Grant for Volumetric optical connectome microscopy of human cerebellar circuitry

      Massachusetts General Hospital Receives a 2021 NIH Grant for $248,993 for Volumetric optical connectome microscopy of human cerebellar circuitry . The principal investigator is Yan Li. Below is a summary of the proposed work. The goal in seeking a K99/R00 Pathway to Independence Award is to establish myself as an independent principal investigator to study the structural-functional relationship of the brain circuitry in normal and brain disorders. The proposed project, driven by the need for understanding the human brain with high-resolution high-throughput tools and my extensive experience in biomedical optics for neuroimaging, aims to establish a versatile tool to ...

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    8. UIUC Receives NIH Grant for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media

      UIUC Receives NIH Grant for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media

      University of Illinois at Urbana-Champaign Receives a 2021 NIH Grant for $653,667 for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media. The principal investigator is Yan Li. Below is a summary of the proposed work. Otitis media (middle ear infection) is a highly prevalent disease, especially in young children. It has been documented that more than 75% of children will have at least one episode of otitis media (OM) by age 3, and many children will have recurrent or chronic OM. In most cases, diagnosis of an ear infection is performed ...

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    9. University of Southern California Receives NIH Grant for High-resolution Elastographic Assessment of the Optic Nerve Head

      University of Southern California Receives NIH Grant for High-resolution Elastographic Assessment of the Optic Nerve Head

      University of Southern California Receives a 2021 NIH Grant for $656,389 for High-resolution Elastographic Assessment of the Optic Nerve Head. The principal investigator is Qifa Zhou. Below is a summary of the proposed work. Glaucoma is a leading cause of irreversible blindness worldwide, affecting over 2.2 million Americans. With an aging population, it is estimated that by 2020 the number of people suffering glaucoma will reach 80 million worldwide, with 11 bilaterally blind. The goal of this study is to develop a novel tool for imaging and measuring elastic properties of the optic nerve head (ONH) and lamina ...

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    10. Oregon Health and Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

      Oregon Health and Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

      Oregon Health and Science University Receives a 2021 NIH Grant for $373,450 for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas. The principal investigator is Yan Li. Below is a summary of the proposed work. To see well, the cornea must maintain near perfect clarity and shape. Several disease processes can distort corneal shape and degrade vision. These include ectasia/keratoconus (stromal thinning and bulging), primary epithelial deformation (contact lens-related warpage, dry eye, epithelial basement membrane dystrophy), and stromal changes (scar, stromal dystrophy, surgery). Some of these conditions can appear similar on standard anterior topography and yet ...

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    11. Want to learn why polarization-sensitive optical coherence tomography is gaining attention? – Webinar May 26th, 2021

      Want to learn why polarization-sensitive optical coherence tomography is gaining attention? – Webinar May 26th, 2021

      This free, live event will take place on May 26 th at 10 am EDT (4 PM CET) and will include an interactive Q&A session. For information and to register please visit this link . After the event a recorded version will be available at www.thorlabs.com/webinars . Abstract: Drs. Matthias Pues and Pablo Stickar from Thorlabs OCT applications team will describe the working principle of polarization-sensitive optical coherence tomography (PS-OCT) and demonstrate it with measurements of an everyday object. They will then discuss the anisotropy traits in the samples that PS-OCT reads out, together with application examples. PS-OCT ...

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      Mentions: Thorlabs
    12. OHSU Receives NIH Grant for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity

      OHSU Receives NIH Grant for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity

      Oregon Health and Science University Receives a 2021 NIH Grant for $377,300 for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity. The principal investigator is Yifan Jian. Below is a summary of the proposed work. The long-term goal of this project is to determine whether optical coherence tomography (OCT) and OCT angiography (OCTA) might lead more accurate and objective diagnosis, earlier intervention, and improved outcomes in retinopathy of prematurity (ROP). International consensus and National Institute of Health (NIH) funded clinical trials over the last 30 years have defined the phenotypic classifications, natural history, prognosis, and ...

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    14. Cornell University Receives a NIH Grant for Real-time Aberration Sensor for Large-Scale Microscopy Deep in the Mouse and Adult Zebrafish Brain

      Cornell University Receives a NIH Grant for Real-time Aberration Sensor for Large-Scale Microscopy Deep in the Mouse and Adult Zebrafish Brain

      Cornell University Receives a 2021 NIH Grant for $1,982,304 for Real-time Aberration Sensor for Large-Scale Microscopy Deep in the Mouse and Adult Zebrafish Brain. The principal investigator is Steven Adie. Below is a summary of the proposed work. Optical imaging holds tremendous promise in our endeavor to understand brain functions. The major challenges for optical brain imaging are depth and speed. Due to optical aberrations and tissue scattering, the penetration depth and imaging speed of optical microscopy in the brains (e.g., mouse) is limited. The constraints in depth and speed make large-scale, deep imaging of mouse brain ...

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    15. Vanderbilt University Receives NIH Grant for smartOCT: A Low-Cost Technology to Detect and Monitor Glaucoma in Outpatient and Primary Care Centers

      Vanderbilt University Receives NIH Grant for smartOCT: A Low-Cost Technology to Detect and Monitor Glaucoma in Outpatient and Primary Care Centers

      Vanderbilt University Receives a 2021 NIH Grant for $404,033 for smartOCT: A Low-Cost Technology to Detect and Monitor Glaucoma in Outpatient and Primary Care Centers. The principal investigator is Audrey Browden. Below is a summary of the proposed work. Glaucoma is the leading cause of irreversible vision loss globally. Nearly 52.7 million people will be affected in 2020, and that number will grow to ~79.8 million by 2040. The prevalence varies by ethnicity, and the rates of undiagnosed primary open angle glaucoma are alarmingly high (50-85%) in white, black and Latino patients. The challenge in glaucoma detection ...

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    16. Cornell University Receives NIH Grant for Ultrahigh-Resolution Quantitative Optical Coherence Elastography of the Tumor Microenvironment In Vivo

      Cornell University Receives NIH Grant for Ultrahigh-Resolution Quantitative Optical Coherence Elastography of the Tumor Microenvironment In Vivo

      Cornell University Receives a 2021 NIH Grant for $400,639 for Ultrahigh-Resolution Quantitative Optical Coherence Elastography of the Tumor Microenvironment In Vivo. The principal investigator is Steven Adie. Below is a summary of the proposed work. The understanding of cancer has evolved rapidly over the last decade. One of the key findings is that altered mechanical properties is not just a symptom of tumors, but can trigger the actual onset of malignancy, and promote tumor progression. The clinical impact of cancer mechanics research, however, is currently hampered by a lack of methods to image the mechanical properties of the tumor ...

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    17. University of Southern California Receives NIH Grant for Cochlear Mechanics in the Mouse

      University of Southern California Receives NIH Grant for Cochlear Mechanics in the Mouse

      University of Southern California Receives a 2021 NIH Grant for $625,265 for Cochlear Mechanics in the Mouse. The principal investigator is John Oghalai. Below is a summary of the proposed work. Sound pressure produces force across the mammalian cochlear partition, ultimately creating a vibratory traveling wave that propagates longitudinally up the cochlear duct. The key feature distinguishing this process from the non-mammalian cochlea is amplification, whereby forces produced by thousands of outer hair cells (OHCs) sharpen and amplify the traveling wave. Our overarching objective is to understand how the complex biomechanics of the 3D multi-cellular and acellular arrangement that ...

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    18. UCSD Receives NIH Grant for Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography Angiography

      UCSD Receives NIH Grant for Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography Angiography

      University of California, San Diego Receives a 2021 NIH Grant for $489,850 for Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography Angiography. The principal investigator is Robert Weinreb Below is a summary of the proposed work. Project Summary Optical coherence tomography angiography (OCTA) has been introduced recently as a non- invasive, 3-dimensional imaging method to visualize and quantify microvasculature throughout the retina. The proposed study evaluates the clinical utility of OCTA measurements compared to standard structural measurements of the optic nerve head (ONH), retinal nerve fiber layer (RNFL) and macula measured using the current clinical imaging standard, spectral ...

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    19. Medical College of Wisconsin Receives NIH Grant for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography.

      Medical College of Wisconsin Receives NIH Grant for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography.

      Medical College of Wisconsin Receives a 2021 NIH Grant for $390,398 for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography. The principal investigator is Iris Kassem. Below is a summary of the proposed work. The Medical College of Wisconsin prioritizes research as one of its missions and includes in its strategic plan “accelerating discovery with cutting-edge, evidence-based research.” With this support we request funds for the shared instrumentation of a Leica Microsystems Proveo 8 ophthalmic surgical microscope with intrasurgical EnFocus optical coherence tomography. The equipment would be used by eleven faculty from four departments from two institutions. We describe four ...

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    20. Postdoctoral Positions in Optical Imaging at Johns Hopkins

      Postdoctoral Positions in Optical Imaging at Johns Hopkins

      Description : We are seeking candidates for two postdoctoral positions on cutting-edge 3D imaging projects funded by NIH. The first position focuses on visible light optical coherence tomography (vis-OCT) , a new ophthalmic imaging technique that offers ultrahigh depth resolution, capillary-level oximetry, and rich retinal scattering spectroscopy. The second position focuses mesoscopic oblique plane microscopy , and/or oblique scanning laser ophthalmoscopy (oSLO) . The candidates will learn and be responsible for the end-to-end design of device, imaging, and data processing. We expect the candidates to be motivated and productive, and are committed to propel the candidates’ academic career. The position is open starting ...

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    21. Heidelberg Engineering and RetInSight to offer AI-based OCT fluid quantification solution

      Heidelberg Engineering and RetInSight to offer AI-based  OCT fluid quantification solution

      Heidelberg Engineering GmbH and RetInSight GmbH intend to interface the RetInSight AI-based fluid monitor application with the Heidelberg Engineering product portfolio, using cloud exchange and application marketplace technologies. Both companies see great potential in the combination of RetInSight’s AI expertise with Heidelberg Engineering’s high-quality images and data management experience. RetInSight utilizes a novel, proprietary algorithm, that supports the detection, localization and quantification of intra- and subretinal fluid in OCT images in an accurate and reliable manner1. The fluid monitor application aims to facilitate early diagnosis and therapeutic guidance in the most common diseases of the retina, i.e ...

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    22. Post-doctoral Associate Positions in Biophotonics at Washington University in St. Louis

      Post-doctoral Associate Positions in Biophotonics at Washington University in St. Louis

      Position description: We are looking for highly motivated individuals to develop advanced optical devices and imaging techniques for novel biomedical applications in vitro and/or in vivo . We have two positions available immediately, one focuses on developing Silicon-based photonic devices for optical coherence tomography (OCT) and the other position focuses on ophthalmic OCT system development. Successful candidates will have opportunities to collaborate with top academic and industry partners. Compensation is commensurate with experience. Qualifications: Ph.D. in Electrical Engineering, Applied Physics, Physics, Biomedical Engineering, or related fields. Position #1: hands-on experience with Silicon photonics design and fabrication. Position #2: hands-on ...

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    23. Postdoctoral Fellow Position in Adaptive Optics OCT at the University of Washington

      Postdoctoral Fellow Position in Adaptive Optics OCT at the University of Washington

      Description The lab of Ram Sabesan at University of Washington’s Department of Ophthalmology & Vision Science Center invites applications for a postdoctoral fellow position. The successful candidate will lead the development and application adaptive optics retinal imaging tools to a) study neural processing in the early visual system of living humans and animal models and b) translate cellular measures of retinal structure and function to patients with retinal disease. The lab’s broad goals involve the application of adaptive optics OCT and adaptive optics SLO to basic vision science and clinical applications (see here and here for example). Projects benefit ...

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    24. New Publications Highlight Clinical Benefits of Avinger PAD Therapies

      New Publications Highlight Clinical Benefits of Avinger PAD Therapies

      Avinger, Inc. (NASDAQ:AVGR), a commercial-stage medical device company marketing the first and only intravascular image-guided, catheter-based system for diagnosis and treatment of Peripheral Artery Disease (PAD), today announced the publication of two clinical studies in peer-reviewed journals, further supporting the clinical benefits of its therapeutic devices. The studies were based on separate clinical case series conducted by physicians at the Division of Cardiovascular Disease and Endovascular Medicine at the Einstein Medical Center in Philadelphia, Pennsylvania. "These two studies demonstrate the utility of Avinger's OCT-guided approach for the treatment of PAD in complex and challenging cases and patient populations ...

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