1. Optical Coherence Tomography News

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    1. MGH Receives NIH Grant for TRD: Functional Imaging

      MGH Receives  NIH Grant  for TRD: Functional Imaging

      Massachusetts General Hospital Receives a 2019 NIH Grant for $338,551 for TRD: Functional Imaging. The principal investigator is Benjamin Vakoc. The program began in 2019 and ends in 2021. Below is a summary of the proposed work. TRD 2 TRD project 2 will develop novel optical coherence tomography (OCT) technologies to address unmet needs in the functional imaging of tissue. Specific Aim #1 addresses the need for high-speed and high- resolution angiographic imaging systems for preclinical research. A new high-speed optical architecture for high-resolution optical coherence microscopy (OCM) will be constructed that is 100 times faster than existing OCM ...

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    2. MGH Receives NIH Grant for the Center for Biomedical OCT Research and Translation

      MGH Receives  NIH Grant for the Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives a 2019 NIH Grant for $749,999 for the Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2021. Below is a summary of the proposed work. Overall the Center for Biomedical OCT Research and Translation seeks to push the technological frontier of optical coherence tomography instrumentation and methods in response to challenges in biology and medicine. Fundamental to our approach, CBORT thrives on an intimate, push-pull relationship between physicists/engineers and biological, pre-clinical and clinical scientists. The most direct impact o the Resource ...

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    3. UIUC Receives NIH Grant for Integration of Raman Spectroscopy and OCT for In-vivo identification of Bacterial Otitis Media

      UIUC Receives NIH Grant for Integration of Raman Spectroscopy and OCT  for In-vivo identification of Bacterial Otitis Media

      University of Illinois at Urbana Champaign Receives a 2019 NIH Grant for $648,154 for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-vivo identification of Bacterial Otitis Media. The principal investigator is Stephen Boppart. The program began in 2019 and ends in 2023. Below is a summary of the proposed work. Otitis media (middle ear infection) is a highly prevalent disease, especially in young children. It has been documented that more than 75% of children will have at least one episode of otitis media (OM) by age 3, and many children will have recurrent or chronic OM ...

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    4. Senior Scientist on Topcon Milpitas California

      Senior Scientist on Topcon Milpitas California

      Overview Topcon is a comprehensive ophthalmic device manufacturer within the worldwide ophthalmic community. It introduced the world’s first commercial back-of-the-eye spectral domain (SD) and swept source (SS) optical coherence tomography (OCT) systems, which have driven innovation in eye-care. More recently, Topcon Healthcare Solutions started to enhance not only its hardware but also its software solutions. To become the leader in diagnostic software, Topcon has developed a new strategic division whose primary objective is to create world-class software solutions for the eye-care industry and beyond. Our products enable the collection and visualization of a wide range of imaging and clinical ...

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    5. International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      International Ocular Circulation Society Inaugural Meeting, August 10, 2019 Portland Oregon

      The International Ocular Circulation Society (IOCS) was co-founded by a group of leading researchers in America, Asia, and Europe in 2018. The inaugural meeting of the new Society will be hosted by David Huang, M.D. and Yali Jia, Ph.D. of the Casey Eye Institute in Portland Oregon on August 10, 2019. The meeting will present 28 papers and 35 posters on technologies on the topics of imaging and measurement of ocular blood flow and oxygen metabolism, vascular anatomy and physiology, and the roles of ocular circulation in retina, optic nerve, neurological, and systemic diseases. The Oregon Health & Science ...

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    6. Veterans Affairs Medical Center in San Francisco Receives a 2019 NIH Grant for Collateral Flow and Stroke Outcome

      Veterans Affairs Medical Center in San Francisco Receives a 2019 NIH Grant for Collateral Flow and Stroke Outcome

      Veterans Affairs Medical Center in San Francisco Receives a 2019 NIH Grant for Collateral Flow and Stroke Outcome. The principal investigator is Jialing Liu. . Below is a summary of the proposed work. Collateral status is an independent predictor of stroke outcome, as well as response to thrombolytic therapies in patients with ischemic stroke. Genetic factors contribute to the extent and development of native collaterals, whereas patients with metabolic syndromes are associated with poor collateral status during acute ischemic stroke. Diabetes increases the risk of stroke and exacerbates ischemic brain damage, although the impact of diabetes on collateral dynamics remains to ...

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    7. Baylor College of Medicine Receives NIH Grant for Biomechanics of Early Cardiogenesis

      Baylor College of Medicine Receives NIH Grant for Biomechanics of Early Cardiogenesis

      Baylor College of Medicine Receives a 2019 NIH Grant for $554,542 for Biomechanics of Early Cardiogenesis. The principal investigator is Irina Larina. The program began in 2018 and ends in 2023. Below is a summary of the proposed work. Human congenital heart defects (CHD) are very common, occurring in nearly 1% of live births. Moreover, cardiovascular (CV) failures are the leading cause of birth defect- related deaths in infants. It is well established that biomechanical stimuli are important regulators of CV development. Thus, defining how mechanical factors are integrated with genetic pathways to coordinate mammalian heart tube function and ...

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    8. University of Washington Receives NIH Grant for Biomechanics of Neural Tube Development Using Brillouin-OCT Multimodality

      University of Washington Receives NIH Grant for Biomechanics of Neural Tube Development Using Brillouin-OCT Multimodality

      University of Washington Receives a 2019 NIH Grant for $663,429 for Biomechanics of Neural Tube Development Using Brillouin-OCT Multimodality. The principal investigator is Kirill Larin. The program began in 2018 and ends in 2023. Below is a summary of the proposed work. The objective of this proposal is to develop a non-contact, all-optical imaging technology to map elastic moduli and forces involved in critical aspects of embryonic development with high 3D resolution. The proposed technology is based on combined Brillouin spectroscopy and Optical Coherence Tomography (OCT), which will be used to gain fundamental understanding of biomechanical factors involved during ...

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    9. Case Western Reserve University Receives NIH Grant for Optical Tools to Assess the Role of Hemodynamics in the Development of Congenital Heart Defects

      Case Western Reserve University Receives NIH Grant for Optical Tools to Assess the Role of Hemodynamics in the Development of Congenital Heart Defects

      Case Western Reserve University Receives a 2019 NIH Grant for $493,857 for Optical Tools to Assess the Role of Hemodynamics in the Development of Congenital Heart Defects. The principal investigator is Michael Jenkins. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. Congenital heart defects (CHDs) are one of the most common and devastating birth defects, afflicting 32,000 babies born in the United States each year, and over 1 million Americans alive today. Altered hemodynamics during development has been shown to be a contributing factor to CHDs, regardless of whether ...

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    10. Lumedica Receives NIH Grant for Low Cost Retinal Optical Coherence Tomography for Point of Care Use

      Lumedica Receives NIH Grant for Low Cost Retinal Optical Coherence Tomography for Point of Care Use

      Lumedica Receives a 2019 NIH Grant for $499,978 for Low Cost Retinal Optical Coherence Tomography for Point of Care Use. The principal investigator is William Brown. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. The objective of this research is to create a clinical prototype of a new optical coherence tomography (OCT) system suitable for diagnostic retinal imaging at the point of care. The target system price will be one third the price of currently available research OCT systems while providing performance comparable to other entry level OCT imaging systems ...

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    11. Avinger Enrolls First 50 Patients in INSIGHT Clinical Trial

      Avinger Enrolls First 50 Patients in INSIGHT Clinical Trial

      Avinger, Inc. (NASDAQ: AVGR), a commercial-stage medical device company marketing the first-ever image-guided, catheter-based system for diagnosis and treatment of Peripheral Artery Disease (PAD), today announced the 50 th patient enrolled in its INSIGHT clinical trial. The INSIGHT trial is a prospective, global, single arm, multi-center study to evaluate the safety and effectiveness of the Pantheris ® Lumivascular atherectomy system for treating in-stent restenosis (ISR) in lower extremity arteries. Dr. Jaafer Golzar, Avinger’s Chief Medical Officer and a highly experienced interventionalist, noted, “We are pleased to have the first 50 cases completed as part of our INSIGHT IDE study. Early ...

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      Mentions: Avinger
    12. Avinger Announces Commercial Launch of Ocelot in Australia

      Avinger Announces Commercial Launch of Ocelot in Australia

      First Patients Treated Successfully in Australia with Image-Guided CTO-Crossing Device REDWOOD, CA / ACCESSWIRE / July 8, 2019 / Avinger, Inc. (NASDAQ: AVGR ), a commercial-stage medical device company marketing the first-ever image-guided, catheter-based system for the diagnosis and treatment of Peripheral Artery Disease (PAD), today announced the commercial launch of its Ocelot image-guided chronic total occlusion (CTO) crossing system in Australia. As part of the Company’s exclusive distribution agreement with Diverse Devices Pty Ltd. for Avinger’s proprietary Lumivascular products in Australia, Ocelot completed the registration process with the Therapeutic Goods Administration (TGA) and is included on the Australian Register of Therapeutic ...

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    13. 7^ INTERNATIONAL CONGRESS ON OCT ANGIOGRAPHY AND ADVANCES IN OCT - Rome, December 13 and 14, 2019

      7^ INTERNATIONAL CONGRESS ON OCT ANGIOGRAPHY AND ADVANCES IN OCT - Rome, December 13 and 14, 2019

      The Rome OCT Angiography meeting returns for its 7th edition. OCT Angiography has come a long way since its early days five ago. The preliminary program is outstanding! It can be accessed now on the website. You will get the most recent research results, everyday applications and observe personally the newest devices. Program is mainly Clinical. However, we will have scientific, histology, technology, imaging (5 sessions), wide field, artificial intelligence (4 sessions), a zoom on the treatments of retinal diseases and retinal degeneration. OCTA technology has hugely improved and industrial antagonism is even more dynamic and passionate. World best experts ...

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      Mentions: Bruno Lumbroso
    14. University of Washington Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy

      University of Washington Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy

      University of Washington Receives a 2019 NIH Grant for $364,428 for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy. The principal investigator is Ruikang Wang. The program began in 2018 and ends in 2022. Below is a summary of the proposed work. The increasing incidence of diabetes in the US population and the inertial wave of aging in Americans will ensure that diabetic retinopathy (DR) remains one of the principal threats to the sight of adult patients and a significant management challenge for the clinical community. It is now clear that the peripheral retina is the ...

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    15. Aeon Imaging Receives NIH Grant for Confocal and Autofluorescence Imaging of Macular Degeneration Using a Low Cost Digital Imager

      Aeon Imaging Receives  NIH Grant for Confocal and Autofluorescence Imaging of Macular Degeneration Using a Low Cost Digital Imager

      Aeon Imaging Receives a 2019 NIH Grant for Confocal and Autofluorescence Imaging of Macular Degeneration Using a Low Cost Digital Imager. The principal investigator is Mathew Muller. Below is a summary of the proposed work. The overall goal of the proposed SBIR Phase II research is to build and evaluate a low cost, multi-mode retinal camera used to detect and manage causes of macular impairment. Age-related macular degeneration (AMD) remains the most common cause of permanent vision loss in the US and many industrialized countries. Treatments with portable lasers and injectable drugs can save sight, but early detection and careful ...

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    16. Case Western Reserve University Receives NIH Grant for Noninvasive Assessment of the Cornea by Diffusion OCT

      Case Western Reserve University Receives NIH Grant for Noninvasive Assessment of the Cornea by Diffusion OCT

      Case Western Reserve University Receives a 2019 NIH Grant for $396,887 for Noninvasive Assessment of the Cornea by Diffusion OCT. The principal investigator is Andrew Rollins. The program began in 2018 and ends in 2023. Below is a summary of the proposed work. Keratoconus is a degenerative disease of the cornea that is a major cause of reduced vision-related quality of life in the United States, often leading to corneal transplantation. Ectasia after refractive surgery is a vision-threatening complication that can occur in apparently low-risk patients despite current screening technology. The biomechanical properties of the cornea play a central ...

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    17. Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery

      Duke University Receives NIH Grant for Intraoperative OCT Guidance of Intraocular Surgery

      Duke University Receives a 2019 NIH Grant for $766,562 for Intraoperative OCT Guidance of Intraocular Surgery. The principal investigator is Joseph Izatt. The program began in 2018 and ends in 2023. Below is a summary of the proposed work. This is a resubmission application for a Bioengineering Research Partnership (BRP) which brings together a highly collaborative and experienced team of engineers and ophthalmic surgeons to advance the state of the art in image-guided surgical interventions. We seek to overcome limitations to the surgeon’s current stereo microscopic view of ocular structures by continuing to integrate optical coherence tomography (OCT ...

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    18. Massachusetts Institute of Technology Receives NIH Grant for Novel Diagnostics with Optical Coherence Tomography.

      Massachusetts Institute of Technology Receives NIH Grant for Novel Diagnostics with Optical Coherence Tomography.

      Massachusetts Institute of Technology Receives a 2019 NIH Grant for $349,765 for Novel Diagnostics with Optical Coherence Tomography. The principal investigator is James Fujimoto. The program began in 1985 and ends in 2020. Below is a summary of the proposed work. This proposal is a resubmission of a competing renewal application for an ongoing collaborative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye Center. This is a multidisciplinary program which integrates imaging technology research, clinical and small animal imaging studies. The specific aims are: Aim 1. Next ...

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    19. Northwestern University Receives NIH Grant for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Optical Detection

      Northwestern University Receives NIH Grant for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Optical Detection

      Northwestern University Receives a 2019 NIH Grant for $535,063 for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Optical Detection. The principal investigator is Hao Zhang. The program began in 2018 and ends in 2022. Below is a summary of the proposed work. Our long-term goal is to develop new functional extensions of optical coherence tomography (vis-OCT) for clinical diagnosis and management of glaucoma. Glaucoma is characterized by a progressive loss of retinal ganglion cells (RGCs) and optic nerve defects and atrophy, afflicting more than 60 million people worldwide. It is often develops slowly with symptoms and damage ...

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    20. Oregon Health and Science University Receives a 2019 NIH Grant for $388,832 for Functional and Structural Optical Coherence Tomography for Glaucoma

      Oregon Health and Science University  Receives a 2019 NIH Grant for $388,832 for Functional and Structural Optical Coherence Tomography for Glaucoma

      Oregon Health and Science University Receives a 2019 NIH Grant for $388,832 for Functional and Structural Optical Coherence Tomography for Glaucoma. The principal investigator is David Huang. The program began in 2013 and ends in 2021. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness. Early diagnosis and close monitoring of glaucoma are important because the onset is insidious and the damage is irreversible. Advanced imaging modalities such as optical coherence tomography (OCT) have been used in the past 2 decades to improve the objective evaluation of glaucoma. OCT has higher axial spatial ...

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    21. Duke University Receives NIH Grant for Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants.

      Duke University Receives NIH Grant for Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants.

      Duke University Receives a 2019 NIH Grant for $142,344 for Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants. The principal investigator is Cynthia Toth. The program began in 2018 and ends in 2020. Below is a summary of the proposed work. The most common cause of childhood blindness in the developed world is cortical blindness; asphyxial injury is a well-known cause of such long-term visual impairment. Hypoxic ischemic encephalopathy (HIE) is also caused by severe perinatal asphyxia, and long-term outcomes include motor, cognitive, and visual deficits, some of which may not be apparent in early infancy and ...

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    22. PhD Student and Postdoctoral Associate Positions at the University of Massachusetts

      PhD Student and Postdoctoral Associate Positions at the University of Massachusetts

      We are looking for highly motivated individuals to join the Biophotonics Imaging Laboratory at UMass Amherst and Worcester. Our lab has interdisciplinary biomedical engineering research programs focusing on the development of novel optical imaging methods for biomedical applications, including functional neuroimaging, early cancer detection, transplant organ evaluation, and tissue engineering. Our optical imaging technologies include optical coherence tomography (OCT), multi-photon microscopy (MPM), fluorescence molecular imaging (FMI), laminar optical tomography (LOT), and endoscopy. A detailed description of our research can be found at: http://blog.umd.edu/biophotonics/research/ Candidates with experiences on biomedical engineering, optical engineering, and/or electrical/mechanical ...

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    23. Two thousand optometrists geared up for OCT at Specsavers

      Two thousand optometrists geared up for OCT at Specsavers

      More than 2000 optometrists at Specsavers have completed an extensive programme of Optical Coherence Tomography (OCT) training, ahead of the installation of the hospital-grade technology in their stores. The milestone has been reached almost half way through the rollout across the UK and Ireland of OCT, which is now in use in 400 stores. Richard Davies of the Bath store was the 2000 th optometrist to complete the set of seven online modules, which cover essentials of OCT, OCT in glaucoma, medical retina and anterior segment, and prudent referrals. Presenting a £100 voucher to Richard in store this week, Paul ...

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    24. Post-Doctoral Researcher Opening at Department of Physics, University of Coimbra, Portugal

      Post-Doctoral Researcher Opening at Department of Physics, University of Coimbra, Portugal

      We opened a tender for selecting a Post-Doctoral Researcher with a contract for an open-ended period of time. We are looking for someone with a Doctoral degree in Biomedical Engineering, Physics Engineering, Physics, Electrotechnical Engineering or a closely related area, knowledge in optoelectronic instrumentation, photonics, optics and electronics and knowledge in programming. The position concerns the ElastoOCT project - Optical Coherence Elastography for imaging retina mechanical properties – and is available at the University of Coimbra, Portugal. The aim of the project is to develop and build an optical coherence elastography system for retinal imaging, with ultrasound excitation and measurement of induced ...

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