1. Optical Coherence Tomography News

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    1. Feature of the Week 08/17/2017: In Vivo Assessment of Periodontal Structures and Measurement of Gingival Sulcus with Optical Coherence Tomography: A Pilot Study

      Feature of the Week 08/17/2017: In Vivo Assessment of Periodontal Structures and Measurement of Gingival Sulcus with Optical Coherence Tomography: A Pilot Study

      There has been increasing interest on the development of clinically acceptable, more sensitive and specific methods for non-invasive diagnosis in Periodontics. In this pilot study, the performance of an Optical Coherence Tomography (OCT) system in imaging periodontal structures in humans was evaluated. Gingival sulcus depth measurements were obtained and compared with traditional probes. In total, 445 sites of 23 periodontally healthy individuals were measured by 3 instruments: North Carolina manual probe, Florida automated probe and OCT at 1325 nm. To obtain quantitative measurements from OCT images, the gingival refractive index was also determined. Discomfort/pain perception and the duration of ...

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    2. Massachusetts General Hospital Receives NIH Grant for Multimodal Mapping of the Neurocircuitry of the Human Prefontal Cortex

      Massachusetts General Hospital Receives NIH Grant for Multimodal Mapping of the Neurocircuitry of the Human Prefontal Cortex

      Massachusetts General Hospital Receives a 2017 NIH Grant for $474,273 for Multimodal Mapping of the Neurocircuitry of the Human Prefontal Cortex. The principal investigator is Anastasia Yendiki. The program began in 2016 and ends in 2020. Below is a summary of the proposed work. The objective of the proposed research is to map the organization of human white matter (WM) with cutting-edge ex vivo imaging technologies. This work will produce microscopic-level information on several long-range WM projections, as well as a more targeted mapping of circuits that serve the prefrontal cortex (PFC). These circuits are of particular interest in ...

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    3. LX Medical Corporation Receives a NIH Grant for High-Resolution Multi-modality Endoscopic Imaging Probes for Diagnosing Rejection in Lung Transplant Recipients

      LX Medical Corporation Receives a NIH Grant for High-Resolution Multi-modality Endoscopic Imaging Probes for Diagnosing Rejection in Lung Transplant Recipients

      LX Medical Corporation Receives a 2017 NIH Grant for $223,403 for High-Resolution Multi-modality Endoscopic Imaging Probes for Diagnosing Rejection in Lung Transplant Recipients. The principal investigator is Andrei Vertikov. The program began in 2017 and ends in 2018. Below is a summary of the proposed work. Lung transplantation is increasingly used to treat patients with end-stage lung diseases. Complications frequently occur with chronic allograft rejection causing most of late morbidity and mortality in lung transplant recipients. Pathological manifestations of chronic rejection mostly affect small airways or bronchioles in the lung, often progressing undetected until the patient presents with an ...

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    4. New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives a 2017 NIH Grant for $654,143 for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. The program began in 2016 and ends in 2019. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness and visual morbidity. Because the disease causes irreversible damage to neural tissue it is of upmost importance to identify glaucoma and its progression at the earliest possible stages. Through advancements in the use of optical coherence tomography (OCT) and other technologies, the long-term goal of this research project ...

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    5. University of Alabama at Birmingham Receives NIH Grant for $43,191 for Occular Phenotyping Core

      University of Alabama at Birmingham Receives NIH Grant for $43,191 for Occular Phenotyping Core

      University of Alabama at Birmingham Receives a 2017 NIH Grant for $43,191 for Occular Phenotyping Core. The principal investigator is Timothy Kraft. A summary of the proposed work is given below. Non-invasive assessment of eye structure and function is essential to both basic and translational research in vision science. Widely used technologies include slit lamp for biomicroscopy of anterior and posterior segment, electroretinography (ERG, for massed retinal signal separable into components), optical coherence tomography (OCT) for display of layered tissues in posterior and anterior segments, imaging of the fundus via multiple modes of visualization (color, autofluorescence, dye-based angiography, infrared ...

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    6. Postdoctoral Fellow, Bioengineering at University of Maryland - College Park

      Postdoctoral Fellow, Bioengineering at University of Maryland - College Park

      We are seeking a postdoctoral fellow to pursue research on developing novel optical imaging devices and applications on cancer diagnosis, functional brain imaging and tissue engineering. Candidates must hold a Ph.D. in engineering, physics, or related fields and have prior experience with Optics, OCT, Microscopy (e.g. fluorescence, confocal, Two-photon), and image analysis software development. Experience with cell culture and/or animals experiments is a plus. Please submit a cover letter with a brief description of research experience, interests, and career goals (≤ 2 pages), CV with complete list of publications, and contact information for 3 references in a single ...

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    7. Research Associate/ Research Fellow at University of Western Australia

      Research Associate/ Research Fellow at University of Western Australia

      Job no: 499166 Work type: full-time Location: Crawley Categories: Engineering and Mathematical Sciences UWA Faculty of Engineering and Mathematical Sciences School of Electrical, Electronic and Computer Engineering 1 year fixed term appointment Level A/B position: $67,352 - $114,250 per annum The University of Western Australia (UWA) is ranked amongst the top Australian universities and a member of the prestigious Group of Eight research-intensive universities ranked among the top 100 universities in the world. About the work area You will be a member of BRITElab in the School of Electrical, Electronic and Computer Engineering within the Faculty of Engineering ...

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    8. Postdoctoral Research Scientist Position at Colgate-Palmolive Company in Piscataway New Jersey

      Postdoctoral Research Scientist Position at Colgate-Palmolive Company in Piscataway New Jersey

      Colgate-Palmolive is a leading global consumer products company, tightly focused on Oral Care, Personal Care, Home Care and Pet Nutrition. Colgate sells its products in over 200 countries and territories around the world under such internationally recognized brand names as Colgate, Palmolive, Speed Stick, Lady Speed Stick, Softsoap, Irish Spring, Protex, Sorriso, Kolynos, elmex, Tom’s of Maine, Sanex, Ajax, Axion, Fabuloso, Soupline and Suavitel, as well as Hill’s Science Diet, Hill’s Prescription Diet and Hill’s Ideal Balance. For more information about Colgate’s global business, visit the Company’s web site at http://www.colgatepalmolive.com ...

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    9. Postdoctoral Fellow: Biophotonics and Computer Vision Stanford University, Stanford, CA

      Postdoctoral Fellow: Biophotonics and Computer Vision Stanford University, Stanford, CA

      The Stanford Biomedical Optics Group (http://sbo.stanford.edu), in close collaboration with clinical researchers in the School of Medicine (urology), seeks highly motivated research associate with excellent computer programming and image processing skills along with a good background / strong interest in optics, microscopy or medical imaging and interest or experience in computer vision. Stanford University provides an outstanding environment for solid technical research with clinical impact. Applicants will work closely with clinical collaborators and will spend a significant amount of time observing and guiding clinical research activities while working on a heavily computer vision programming-­‐oriented research project. Time ...

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    10. Massachusetts General Hospital Receives NIH Grant for Blood Flow-Based Guidance and Diagnostics Using OCT

      Massachusetts General Hospital Receives NIH Grant for Blood Flow-Based Guidance and Diagnostics Using OCT

      Massachusetts General Hospital Receives a 2017 NIH Grant for $173,504 for Blood Flow-Based Guidance and Diagnostics Using OCT. The principal investigator is Nestor Uribe-Patarroyo. The program began in 2017 and ends in 2021. Below is a summary of the proposed work. Diseases diagnosed with assessment of blood flow account for 29% of deaths in the US and are leading causes of premature morbidity, including visual disorders which carry an economic burden of $35 bil- lion per year. The heart disease with the most impact on public health is coronary artery disease (CAD); more than one million percutaneous coronary interventions ...

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    11. Indiana University Receives NIH Grant for Imaging Structure and Function of the Photoreceptor-RPE-Choriocapillaris Complex

      Indiana University Receives NIH Grant for Imaging Structure and Function of the Photoreceptor-RPE-Choriocapillaris Complex

      Indiana University Receives a 2017 NIH Grant for $461,610 for Imaging Structure and Function of the Photoreceptor-RPE-Choriocapillaris Complex. The principal investigator is Donald Miller. The program began in 2007 and ends in 2021. Below is a summary of the proposed work. Human vision starts when photoreceptors collect and respond to light. Photoreceptors do not function in isolation though, but share close interdependence with neighboring photoreceptors, retinal pigment epithelium (RPE) cells, and choriocapillaris (CC). These close interactions underlie normal function of photoreceptors, but also the entire photoreceptor-RPE-CC complex, the primary site of most retinal dystrophies including age-related macular degeneration (AMD ...

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    12. Massachusetts General Hospital Receives NIH Grant for Low Risk In VIvo Optical Diagnosis of IPF with Optical Imaging

      Massachusetts General Hospital Receives NIH Grant for Low Risk In VIvo Optical Diagnosis of IPF with Optical Imaging

      Massachusetts General Hospital Receives a 2017 NIH Grant for $179,120 for Low Risk In VIvo Optical Diagnosis of IPF with Optical Imaging. The principal investigator is Lida Hariri. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. Idiopathic pulmonary fibrosis (IPF) is a progressive, ultimately fatal form of idiopathic interstitial pneumonitis (IIP), with a 3 year survival rate of 0%. Diagnostic certainty of IPF is critical to patient management and therapeutic decision-making. Two new FDA-approved therapies, pirfenidone and nintedanib, have been shown to slow disease progression in IPF and brought new ...

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    13. Cleveland Clinic Receives a NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives a NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives a 2017 NIH Grant for $203,124 for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery. The principal investigator is Justis Ehlers. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Optical coherence tomography (OCT) has revolutionized the management of ophthalmic diseases with the precise anatomic information it provides with non-invasive imaging. The high-resolution cross-sectional tissue details make OCT a natural complement to ophthalmic surgery. Intraoperative OCT (iOCT) has the potential to provide real-time feedback to surgeons thus improving surgical care and outcomes. This research activity will focus on translating ...

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    14. Duke University Receives NIH Grant for Arbitrary Viewpoint Robotic Surgery

      Duke University Receives NIH Grant for Arbitrary Viewpoint Robotic Surgery

      Duke University Receives a 2017 NIH Grant for $4,165 for Arbitrary Viewpoint Robotic Surgery. The principal investigator is Mark Draelos. The program began in 2016 and ends in 2019. Below is a summary of the proposed work. Modern ophthalmic surgery depends on the stereo microscope for surgical field visualization to the extent that procedures best performed from alternate viewpoints are difficult if not impossible due to an inadequate view and non-intuitive surgical maneuvers. We seek to overcome limitations which physically couple the surgeon to both the stereo microscope and hand-held surgical instruments. This current paradigm causes ophthalmic mi- crosurgeons ...

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    15. Cornell University Receives NIH Grant for Development of Hybrid Adaptive Optics for Multimodal Microscopy Deep in The Mouse Brain

      Cornell University Receives NIH Grant for Development of Hybrid Adaptive Optics for Multimodal Microscopy Deep in The Mouse Brain

      Cornell University Receives a 2017 NIH Grant for $244,625 for Development of Hybrid Adaptive Optics for Multimodal Microscopy Deep in The Mouse Brain. The principal investigator is Steven Adie. The program began in 2017 and ends in 2019. Below is a summary of the proposed work. Optical imaging holds tremendous promise in our endeavor to understand brain functions. The major challenges for optical brain imaging are depth and speed. Due to strong tissue scattering, the penetration depth and imaging speed of optical microscopy in the mouse brain is very limited. These constraints in depth and speed make large scale ...

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    16. Optovue First in US to Receive FDA Clearance for Corneal Epithelial Thickness Mapping New Mapping Technique May be Early Indicator of Ocular Health

      Optovue First in US to Receive FDA Clearance for Corneal Epithelial Thickness Mapping New Mapping Technique May be Early Indicator of Ocular Health

      Optovue announced today that the U.S. Food and Drug Administration (FDA) has cleared the company’s epithelial thickness mapping software (epi-mapping) for quantitative measurements of the epithelial and stromal layers of the cornea. Epi-mapping is the first non-contact, quantitative method for corneal epithelia and stromal measurements, and it is the first and only FDA-cleared product indicated to provide corneal epithelia and stromal measurements that aid in the diagnosis, documentation and management of ocular health and diseases in the adult population. “The measurement of corneal epithelial thickness is becoming more recognized as a vital part of assessing patients for refractive ...

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      Mentions: Optovue Jay Wei FDA
    17. Massachusetts General Hospital Receives NIH Grant for Algorithms for MR and OCT-Based Architectonic and Laminar Segmentation

      Massachusetts General Hospital Receives  NIH Grant for Algorithms for MR and OCT-Based Architectonic and Laminar Segmentation

      Massachusetts General Hospital Receives a 2017 NIH Grant for $603,912 for Algorithms for MR and OCT-Based Architectonic and Laminar Segmentation. The principal investigator is Bruce Fischl. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. The human brain is made up of an array of functionally and structurally defined regions. Localizing these regions is critical for early diagnosis of an array of diseases such as Alzheimer's disease (AD), as well as for neuroscientific research aimed at understanding the brain's functional and structural properties and clinical intervention in drug-resistant depression ...

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    18. Feature Of The Week 08/06/2017: Depth-resolved multimodal imaging: Wavelength modulated spatially offset Raman spectroscopy with OCT

      Feature Of The Week 08/06/2017: Depth-resolved multimodal imaging: Wavelength modulated spatially offset Raman spectroscopy with OCT

      There is now a major drive to obtain complementary information using photonics approaches for biomedical studies. Such multimodality can improve diagnosis and increase the accuracy of determining the sample under investigation. A key advance to address this goal would be to obtain molecular as well as morphological information in a given 3D volume. Optical coherence tomography (OCT) is very powerful and can deliver morphological information at depths of up to millimeters. Raman is an ideal companion as it may deliver molecular information but is typically hampered by its poor penetration into a sample, of only 1/10 of a millimeter ...

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    19. Notal Vision Welcomes Roni Amiel as Chief Information Officer

      Notal Vision Welcomes Roni Amiel as Chief Information Officer

      Notal Vision, Ltd., a privately-held ophthalmic company focused on cloud-based, patient-activated, home telemonitoring technologies, is pleased to announce the appointment of Roni Amiel as Chief Information Officer (CIO). In this newly created position, Mr. Amiel will be responsible for advancing the Company's cloud-based technology and capabilities to expand their competitive advantage, and will report to Quinton Oswald , Chief Executive Officer of Notal Vision. "Drawing on his extensive information technology (IT) leadership and medical systems expertise, Roni will help us execute our strategic goals so that we can continue to deliver an outstanding patient and physician experience. Elevating this IT ...

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      Mentions: Notal Vision
    20. Ph.D. Student Position in Optical Coherence Tomography at University of Basel in Switzerland

      Ph.D. Student Position in Optical Coherence Tomography at University of Basel in Switzerland

      The Department of Biomedical Engineering (DBE) has recently been awarded a Flagship project from the Werner Siemens Foundation (Zug/Switzerland). The principal aim of this interdisciplinary project called Minimally Invasive Robot Assisted Computer-guided LaserosteotomE (MIRACLE) is the development of a minimally invasive robotic endoscope for cutting bone with laser light. The successful PhD candidate will be part of an interdisciplinary team of biomedical engineers, mechatronics engineers, computer scientists, physicists, and medical doctors. He or she will be able to contribute to the development of a disruptive technology in robotic surgery. Topic Description In this project, the Ph.D. candidate will ...

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      Mentions: Siemens Azhar Zam
    21. Feature Of The Week 07/24/2017: Spectral Domain Optical Coherence Tomography for Non-Destructive Testing of Protection Coatings on Metal Substrates

      Feature Of The Week 07/24/2017: Spectral Domain Optical Coherence Tomography for Non-Destructive Testing of Protection Coatings on Metal Substrates

      Industrial monuments and other artefacts of vanishing industries have to be preserved as cultural heritage. For example, in Germany next year the public subsidy for the mining industry will end and with this the active mining will end as well. The Deutsches Bergbau-Museum in Bochum as one of the largest of its kind and as a research institution of the Leibnitz association is committed to preserve the cultural heritage of the mining industry. Thus it is facing the huge task to conserve a lot of mining industry objects in their actual authentic appearance, ranging from small tools like hammers to ...

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    22. Viewing a Weld Seam in 360°: New Scan Solution Utilizes OCT Technology to Coaxially Track and Inspect Seams

      Viewing a Weld Seam in 360°: New Scan Solution Utilizes OCT Technology to Coaxially Track and Inspect Seams

      At the Laser World of Photonics tradeshow in Munich, Germany, Blackbird Robotersysteme GmbH (acknowledged remote welding expert and SCANLAB GmbH associate company) will present an entirely new scan solution prototype with integrated distance sensor. Based on optical coherence tomography (OCT), the system detects and measures 3D laser weld seam topographies in high resolution. This is particularly advantageous for industrial system integrators and users looking to secure process safety and comprehensive quality management without a separate monitoring solution. In healthcare OCT has proven itself as an examination technique for opththamology, skin analysis, cancer diagnosis and more. For patients, this optical measurement ...

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    23. Two Engineering Openings at Startup Company Opticent Health

      Two Engineering Openings at Startup Company Opticent Health

      Opticent, Inc. (Opticent Health – www.opticenthealth.com) is a start-up company commercializing an in-house developed patent portfolio related to visible-light optical coherence tomography (OCT) targeting the ophthalmic market. Opticent Health’s core technologies were developed at Northwestern University. Since its founding, Opticent Health has experienced rapid market adoption of its OCT instruments and rapid commercial expansion. Opticent Health is located in Evanston IL, part of the greater Chicago metropolitan area. The company’s management team, with guidance from its prominent advisory board, is expanding its engineering staff and seeks highly qualified personnel for the following two positions: 1. Ph.D ...

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    24. Michelson Diagnostics Secures CPT codes for Optical Coherence Tomography Imaging of Skin

      Michelson Diagnostics Secures CPT codes for Optical Coherence Tomography Imaging of Skin

      Michelson Diagnostics announces that the American Medical Association (AMA) CPT Editorial Panel recently approved two new Category III CPT codes for Optical Coherence Tomography (OCT) imaging of skin. Code 0470T is for OCT microstructural and morphological imaging of skin, image acquisition, interpretation and report for a first lesion; code 0471T is the same for each additional lesion. The new Category III codes, which are for emerging technologies, services, and procedures, are effective July 1, 2017. Michelson Diagnostics pursued approval of this code at the AMA CPT Panel meeting in October 2017, receiving support from the American Academy of Dermatology. “Obtaining ...

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