1. Optical Coherence Tomography News

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    1. HP-OCT™ wins Victorian AEEA award – nominated for Sir William Hudson award

      HP-OCT™ wins Victorian AEEA award – nominated for Sir William Hudson award

      Cylite Pty Ltd, a developer and manufacturer of 4 th Generation OCT systems for Ophthalmology and Optometry, is thrilled to announce it has won the Australian Engineering Excellence Award Victoria. The Australian Engineering Excellent Awards first began in 1988, after a decade of celebrating local projects through an Engineers Australia office. Brought to the national stage, an excellence award recognises outstanding achievement in engineering and the invaluable contribution that engineering makes to the economy, community and environment. Winning projects exhibit excellence, distinction, merit, perfection and quality. Kylee Hall, Cylite’s VP Sales and Marketing Manager commented, ”It is such an ...

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      Mentions: Cylite
    2. Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University

      Postdoctoral Scholar in High Resolution Retinal Imaging at The Ohio State University

      A NIH funded Post Doctoral Scholar position is available in the laboratory of Drs. Nathan Doble and Stacey Choi in the College of Optometry/Department of Ophthalmology and Visual Science at The Ohio State University (OSU). The successful candidate will work within a highly collaborative research environment focused on the development and use of novel high-resolution optical instrumentation for the study of retinal structure and function. The candidate will be expected to assist with construction and validation of novel instrumentation as well as the collection and analysis of the experimental data; preparation of research results for publication and talks; writing ...

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    3. Avinger Receives FDA Clearance of Ocelaris Next Generation Image-guided CTO Crossing System

      Avinger Receives FDA Clearance of Ocelaris Next Generation Image-guided CTO Crossing System

      Avinger, Inc. (NASDAQ:AVGR), a commercial-stage medical device company marketing the first and only intravascular image-guided, catheter-based system for diagnosis and treatment of patients with Peripheral Artery Disease (PAD), today announced that the Company received 510(k) clearance from the U.S. Food & Drug Administration (FDA) for its Ocelaris next generation image-guided chronic total occlusion (CTO) crossing system. The new device will be marketed under the brand name TIGEREYE™ to reinforce its highly differentiated benefit of providing real-time imaging from inside the vessel during a CTO-crossing procedure. TIGEREYE is a product line extension of Avinger's Ocelot family of image-guided ...

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      Mentions: FDA Avinger
    4. University of California at San Francisco Receives NIH Grant for Infrared Methods for Lesion Activity Assessment

      University of California at San Francisco Receives NIH Grant for Infrared Methods for Lesion Activity Assessment

      University of California at San Francisco Receives a 2020 NIH Grant for $45,564 for Infrared Methods for Lesion Activity Assessment. The principal investigator is Nai-Yaun Chang. Below is a summary of the proposed work. The overall objective of this proposed research is to develop methods for the clinical assessment of lesion structure and activity. Improved imaging technologies employing non-ionizing radiation will significantly improve caries diagnosis and management. It is not sufficient to simply detect carious lesions, methods are needed to assess the activity of the lesion and determine if chemical intervention is needed. The central hypothesis underlying this proposal ...

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    5. Medical College of Wisconsin Receives NIH Grant for Assessing Photoreceptor Structure and Function in Normal and Diseased Retinae

      Medical College of Wisconsin Receives NIH Grant for Assessing Photoreceptor Structure and Function in Normal and Diseased Retinae

      Medical College of Wisconsin Receives a 2020 NIH Grant for $486,444 for Assessing Photoreceptor Structure and Function in Normal and Diseased Retinae. The principal investigator is Joseph Carroll. Below is a summary of the proposed work. Inherited retinal degenerations affect approximately 1 in 1,500 individuals in the US, and given the extreme genotypic and phenotypic heterogeneity, the prospect of treating these devastating diseases is a formidable task. Nevertheless, trials examining novel therapeutic strategies are underway. An important key to success in the early phases of such trials is selection of patients with reasonable therapeutic potential – for example, a ...

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    6. University of Texas Health Science Center in Houston ReceivesNIH Grant for Combined Optical Coherence Elastography and Tomography for Assessing Skin Involvement in Systemic Sclerosis

      University of Texas Health Science Center in Houston ReceivesNIH Grant for Combined Optical Coherence Elastography and Tomography for Assessing Skin Involvement in Systemic Sclerosis

      University of Texas Health Science Center in Houston Receives a 2020 NIH Grant for $398,791 for Combined Optical Coherence Elastography and Tomography for Assessing Skin Involvement in Systemic Sclerosis. The principal investigator is Shervin Assassi. Below is a summary of the proposed work. Systemic sclerosis (SSc-scleroderma) is an autoimmune disease leading to widespread fibrosis in skin and internal organs. Skin involvement is a prominent source of distress and morbidity in this disease. The modified Rodnan skin score (mRSS) as the current gold standard for assessment of skin thickening has limited accuracy, high inter-observer variability, requires extensive training which have ...

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    7. University of Southern California Receives NIH Grant for Comb Light Source/Imaging Spectrometer for Advanced Spectral Domain Optical Coherence Tomography

      University of Southern California Receives NIH Grant for Comb Light Source/Imaging Spectrometer for Advanced Spectral Domain Optical Coherence Tomography

      University of Southern California Receives a 2020 NIH Grant for $239,351 for Comb Light Source/Imaging Spectrometer for Advanced Spectral Domain Optical Coherence Tomography. The principal investigator is Brian Applegate. Below is a summary of the proposed work. There is a growing interest in the development of functional imaging with Optical Coherence Tomography (OCT). Many of these approaches to functional imaging rely on the exquisite phase sensitivity of the OCT interferometer. These include well established techniques like Doppler OCT for measuring blood flow as well as emerging applications like OCT elastography for measuring mechanical properties, and Magnetomotive OCT and ...

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    8. General Electric Receives NIH Grant for Multi-Scale 3-D Image Analytics for High Dimensional Spatial Mapping of Normal Tissue

      General Electric Receives NIH Grant for Multi-Scale 3-D Image Analytics for High Dimensional Spatial Mapping of Normal Tissue

      General Electric Receives a 2020 NIH Grant for $750,000 for Multi-Scale 3-D Image Analytics for High Dimensional Spatial Mapping of Normal Tissue. The principal investigator is Yousef Al-Kofahi. Below is a summary of the proposed work. The overall goal of the proposed project is to develop open-source software and algorithms for 3-D reconstruction and multi-scale mapping of normal tissues. Another significant goal is to evaluate effects of aging and environmental factors on molecular and structural architecture of skin. We will leverage our mature (TRL8) technology for multiplexed 2-D imaging (Cell DIVE™), and our vast experience in 2-D image analytics ...

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    9. PhotoniCare Announces More Than $7 Million in Funding for Commercial Expansion of First-In-Class Ear Imaging Technology

      PhotoniCare Announces More Than $7 Million in Funding for Commercial Expansion of First-In-Class Ear Imaging Technology

      PhotoniCare, Inc., a company dedicated to revolutionizing healthcare by providing physicians with better diagnostic tools, today announced an oversubscribed $5.2 million Series A financing led by i2E Management Company Inc., with co-investment from OSF Ventures, Sony Innovation Fund, and Dreampact Ventures. The company also announced that it has received a $2.1 million Phase II Small Business Innovation Research ( SBIR ) grant from the National Institutes of Health ( NIH ). The competitive NIH SBIR program funds early-stage small businesses seeking to commercialize innovative biomedical technologies. In January, PhotoniCare announced that the U.S. Food and Drug Administration (FDA) had granted clearance ...

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    10. Johns Hopkins Receives NIH Grant for Enabling Technology for Image-Guided Robot-Assisted Sub-Retinal Injections.

      Johns Hopkins Receives NIH Grant for Enabling Technology for Image-Guided Robot-Assisted Sub-Retinal Injections.

      Johns Hopkins Receives a 2020 NIH Grant for $504,023 for Enabling Technology for Image-Guided Robot-Assisted Sub-Retinal Injections. The principal investigator is Iulian Iordachita. Below is a summary of the proposed work. The goal of this proposal is to design, develop and evaluate a novel clinically compatible surgical platform for enhancing the retina surgeon's ability to provide therapy to the subretinal domain. Efficient, safe, reproducible delivery methods would enable safe and precise delivery of stem cell, nanoparticle and gene therapies for prevalent ocular diseases including but not limited to Age-related Macular Degeneration (AMD). The proposed cooperative surgical robot utilizes ...

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    11. University of Southern California Receives NIH Grant for Imaging Cerebral and Retinal Microvasculature in Cerebral Small Vessel Disease

      University of Southern California Receives NIH Grant for Imaging Cerebral and Retinal Microvasculature in Cerebral Small Vessel Disease

      University of Southern California Receives a 2020 NIH Grant for $299,643 for Imaging Cerebral and Retinal Microvasculature in Cerebral Small Vessel Disease. The principal investigator is Danny Wang. Below is a summary of the proposed work. While Alzheimer's disease (AD) is the most common cause of dementia, the contribution of vascular factors to cognitive impairment and dementia is becoming increasingly recognized. Vascular cognitive impairment and dementia (VCID) is most commonly caused by cerebral small vessel disease (SVD). To date, cerebral small vessels including arterioles, capillaries and venules are inaccessible to existing imaging technologies. Characteristic parenchymal lesions on MRI ...

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    12. Post Doc Positions in Optical Coherence Tomography and Optical Imaging at University of Washington

      Post Doc Positions in Optical Coherence Tomography and Optical Imaging at University of Washington

      There are a number of postdoctoral/professional scientist positions immediately available in Wang Lab [Biophotonics and Imaging Laboratory (BAIL)], Department of Bioengineering and Department of Ophthalmology, University of Washington. We are located in beautiful and best to live Seattle area. We are looking for highly motivated individuals to join our vibrant lab to develop innovative optical imaging techniques (e.g. optical coherence tomography and angiography, and smartphone-based healthcare technology) for ophthalmology, dermatology, dentistry, and brain imaging applications. Clinical translation is the focus of our research activities. Our work involves profound knowledge of biomedical optics, system engineering and integration, image processing ...

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    13. Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital

      Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital

      Employer Description Guillermo J. Tearney, M.D., Ph.D. Tearney Lab – Wellman Center for Photomedicine Massachusetts General Hospital Until recently, visualizing the architectural and cellular morphology of human tissue has required histopathological examination. Samples would be excised from the patient, processed, sectioned, stained and viewed under a microscope. In addition to being invasive, time consuming and costly, the static nature of conventional pathology prohibits the study of biological dynamics and function. The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities ...

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    14. Postdoctoral Research Fellowships (In Vivo Microscopy) at Massachusetts General Hospital

      Postdoctoral Research Fellowships (In Vivo Microscopy) at Massachusetts General Hospital

      Employer Description Guillermo J. Tearney, M.D., Ph.D. Tearney Lab – Wellman Center for Photomedicine Massachusetts General Hospital Until recently, visualizing the architectural and cellular morphology of human tissue has required histopathological examination. Samples would be excised from the patient, processed, sectioned, stained and viewed under a microscope. In addition to being invasive, time consuming and costly, the static nature of conventional pathology prohibits the study of biological dynamics and function. The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities ...

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    15. Massachusetts General Hospital Receives NIH Grant for Volumetric Optical Coherence Tomography of Human Cerebellar Circuitry

      Massachusetts General Hospital Receives NIH Grant for Volumetric Optical Coherence Tomography of Human Cerebellar Circuitry

      Massachusetts General Hospital Receives a 2020 NIH Grant for $248,993 for Volumetric Optical Coherence Tomography of Human Cerebellar Circuitry. The principal investigator is Hui Wang. Below is a summary of the proposed work. The goal in seeking a K99/R00 Pathway to Independence Award is to establish myself as an independent principal investigator to study the structural-functional relationship of the brain circuitry in normal and brain disorders. The proposed project, driven by the need for understanding the human brain with high-resolution high-throughput tools and my extensive experience in biomedical optics for neuroimaging, aims to establish a versatile tool to ...

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    16. AI-based OCT analysis of AREDS2 10-Y follow-on study demonstrates superior performance over retina specialists

      AI-based OCT analysis of AREDS2 10-Y follow-on study demonstrates superior performance over retina specialists

      Data analysis from Age-Related Eye Disease Study 2 10-year Follow-On Study (AREDS2-10Y) participants shows that the Notal Optical Coherence Tomography (OCT) Analyzer, which uses machine learning and image recognition computational techniques to identify, quantify and map intra- and subretinal fluid in wet age-related macular degeneration (AMD), achieved a higher level of accuracy than that of retina specialists, who had imperfect accuracy and low sensitivity in detecting retinal fluid. The study, recently published in Opthalmology, was presented at the American Society of Retina Specialist virtual annual meeting on July 24, 2020. “The study results show how challenging it is to identify ...

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      Mentions: FDA Notal Vision
    17. Two postdoctoral positions and a PhD position at the Biomedical Engineering Department The University of Illinois at Chicago (UIC)

      Two postdoctoral positions and a PhD position at the Biomedical Engineering Department The University of Illinois at Chicago (UIC)

      Two postdoctoral positions and one PhD position are available in OPIRA lab in the Biomedical Engineering Department, the University of Illinois at Chicago ( UIC ). 1. The first postdoctoral fellow will contribute to the design, development, and optimization of a photoacoustic tomography system for infant brain imaging. Other responsibilities include conducting phantom and animal imaging experiments, data analysis. More details about the projects will be discussed during the interview. This project is hosted by the Biomedical Engineering Department at UIC , collaborating with UIC Medical School, Biomedical Engineering Department at the University of Michigan and Harvard Medical School. Requirements include: ( Ph.D ...

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    18. University of Maryland Receives NIH Grant for In Vivo Assessment of Meningeal Inflammation and its Clinical Impact in Multiple Sclerosis by 7 Tesla MRI

      University of Maryland Receives NIH Grant for In Vivo Assessment of Meningeal Inflammation and its Clinical Impact in Multiple Sclerosis by 7 Tesla MRI

      University of Maryland Receives a 2020 NIH Grant for $609,639 for In Vivo Assessment of Meningeal Inflammation and its Clinical Impact in Multiple Sclerosis by 7 Tesla MRI. The principal investigator is Daniel Harrison. Below is a summary of the proposed work. Although MRI is the major diagnostic and prognostic tool used in the care of patients with multiple sclerosis (MS), many aspects of MS pathology are still not well visualized. Recent histopathologic studies in MS have shed light on a previously unrecognized phenomenon without a proven MRI correlate- meningeal inflammation. Pathologic data suggests that meningeal inflammation in MS ...

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    19. Massachusetts General Hospital Receives NIH Grant for Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives NIH Grant for Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives a 2020 NIH Grant for $420,000 for Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. Below is a summary of the proposed work. Recent progress in the Center for Biomedical OCT Research and Translation has resulted in 1) the ability to detect and map polarimetric signatures for tissue characterization, and 2) fast and effective methods for quantitative angiographic imaging with microscopic resolution over fields of view as large as 10’s of cubic centimeters. Motivated by recent insights from autopsy and clinical studies of Alzheimer’s disease patients, we seek ...

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    20. HP-OCT™ from Cylite receives Australian Made certification

      HP-OCT™ from Cylite receives Australian Made certification

      Cylite Pty Ltd, a developer and manufacturer of 4 th Generation OCT systems for Ophthalmology and Optometry, is pleased to announce that it has been awarded Australian Made status. The Australian Made, Australian Grown logo is administered by Australian Made Campaign Limited (AMCL), a not-for-profit public company established in 1999 by the Australian Chamber of Commerce & Industry (ACCI) and the network of state and territory chambers of commerce, with the cooperation of the Federal Government. In 2002, the Federal Government transferred ownership of the logo to AMCL via a Deed of Assignment and Management, which sets out strict conditions under ...

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      Mentions: Cylite
    21. Northwestern University Receives NIH Grant for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Adoption

      Northwestern University Receives NIH Grant for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Adoption

      Northwestern University Receives a 2020 NIH Grant for $516,102 for Investigating Nanoscale Neuronal Damages in Early Glaucoma Towards Clinical Adoption. The principal investigator is Hao Zhang. Below is a summary of the proposed work. Our long-term goal is to develop new functional extensions of optical coherence tomography (vis-OCT) for clinical diagnosis and management of glaucoma. Glaucoma is characterized by a progressive loss of retinal ganglion cells (RGCs) and optic nerve defects and atrophy, afflicting more than 60 million people worldwide. It is often develops slowly with symptoms and damage that are not noticed at early stage. Caring for those ...

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    22. Legacy Emanuel Hospital and Health Center Receives NIH Grant for Advancing OCT Evolution to Reveal Early-Stage Changes in Glaucoma

      Legacy Emanuel Hospital and Health Center Receives NIH Grant for Advancing OCT Evolution to Reveal Early-Stage Changes in Glaucoma

      Legacy Emanuel Hospital and Health Center Receives a 2020 NIH Grant for $543,351 for Advancing OCT Evolution to Reveal Early-Stage Chalnges in Glaucoma. The principal investigator is Brad Fortune. Below is a summary of the proposed work. Currently, diagnosis of glaucoma and patient management decisions are often informed by thinning of the optic nerve head (ONH) neuro-retinal rim, peripapillary retinal nerve fiber layer (RNFL), and macular inner retinal layers, as detected using optical coherence tomography (OCT). These measurements are useful because they are predictive of subsequent visual field decline, and of faster rates of subsequent thinning. However, by the ...

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    23. Rowe Technical Design, Inc. announces their newest tissue phantom/Model Eye for OCT is now in production!

      Rowe Technical Design, Inc. announces their newest tissue phantom/Model Eye for OCT is now in production!

      Rowe Technical Design (RTD), developers of the broadest selection of optical tissue phantoms for OCT and fundus imaging has announced that their latest version of the Cornea tissue phantom for OCT has now been released for full serial production. “We’re excited because this is our fifth serial production model eye, following up on the very successful anterior chamber model eye” notes T. Scott Rowe, company founder and president. “We are extremely pleased with the customer feedback so far, ready for successful volume manufacturing. The Cornea model eye incorporates an 11.0 mm diameter cornea with 470 um central corneal ...

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      Mentions: T. Scott Rowe
    24. Change in Leadership at OBEL, The University of Western Australia

      Change in Leadership at OBEL, The University of Western Australia

      Even before I left the University of Kent in 1993, I had noticed how cool optical coherence tomography (OCT) was – and how similar it was to some of my own work on coherence multiplexing for communications. Kent was where I did my PhD, obtained my first faculty appointment, and hired my dear friend Adrian Podoleanu to work on telecoms – not OCT! Back in Australia in 1995, I arranged for Eric Swanson to speak at our national meeting – Australian Conference on Optical Fibre Technology – things were moving fast in OCT, but I was working…. still in telecoms. It wasn’t until ...

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