1. Optical Coherence Tomography News

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    1. Postdoctoral Research Fellow Position within the PARIS High Resolution Retinal Imaging Group

      Postdoctoral Research Fellow Position within the PARIS High Resolution Retinal Imaging Group

      A postdoctoral research fellow position is available within the PARIS high resolution retinal imaging group at the Quinze Vingts National Ophthalmology Hospital and Vision Institute in Paris, France. This is an excellent opportunity for a candidate to use adaptive optics ophthalmoscopy (AOO) and optical coherence tomography to conduct visual optics research in a clinical ophthalmology setting. The postdoc will work with a team of clinicians, engineers and scientists to develop, adapt and apply novel AOO modalities to imaging retinal disease in the context of a multi-centric project funded by the European Research Council (ERC), involving renowned partners expert in high ...

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    2. Boston Medical Center Receives NIH Grant for Eye To Brain: Eye Biomarkers and Cognition

      Boston Medical Center Receives NIH Grant for Eye To Brain: Eye Biomarkers and Cognition

      Boston Medical Center Receives a 2019 NIH Grant for $197,189 for Eye To Brain: Eye Biomarkers and Cognition. The principal investigator is Manju Subramanian. The program began in 2019 and ends in 2021. Below is a summary of the proposed work. The goal of our research is to identify ocular biomarkers that have diagnostic and potentially prognostic utility in Alzheimer's Disease (AD), and establish a relationship to cognition. We seek to determine this relationship in an already established cohort of patients (the Vitreous Biomarkers Study, or VBS) with eye disease where protein biomarkers have been identified in the ...

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    3. Research Associate / Postdoctoral Fellow in Adaptive Optics and Optical Coherence Tomography at Indiana University

      Research Associate / Postdoctoral Fellow in Adaptive Optics and Optical Coherence Tomography at Indiana University

      The Advanced Ophthalmic Imaging Laboratory at Indiana University is looking to fill a postdoctoral fellow or research associateposition. The successful candidate will join a team of scientists and engineers that are developing adaptive optics–optical coherence tomography (AO-OCT) for studying structure and function of the living human retina at the cellular level. The system is opening exciting new directions to study both normal and pathological vision. The laboratory ( www.opt.indiana.edu/dtmiller/Index.aspx ) is part of an active and well-funded community of vision scientists and engineers working in the areas of visual optics, retinal imaging, OCT, and adaptive ...

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    4. Physical Sciences Receives NIH Grant for Optical Prove for Real-Time Assessment of Periodontal Health Status

      Physical Sciences Receives NIH Grant for Optical Prove for Real-Time Assessment of Periodontal Health Status

      Physical Sciences Incorporated Received a 2019 NIH Grant for $641,715 for Optical Prove for Real-Time Assessment of Periodontal Health Status. The principal investigator is Nicusor Iftimia. The program began in 2013 and ends in 2020. Below is a summary of the proposed work. Physical Sciences, Inc. (PSI), in collaboration with The Forsyth Institute, Cambridge, MA is proposing to develop a technology that will address a major unmet medical need in periodontology: the lack of tools to quantitatively and objectively assess the health/disease status of the gingival soft tissues. The proposed technology will combine high resolution micro-Optical Coherence Tomography ...

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    5. Avinger Announces Publication of Study Demonstrating Positive Clinical Outcomes for Patients Treated with Pantheris Prior to Antirestenotic Therapy

      Avinger Announces Publication of Study Demonstrating Positive Clinical Outcomes for Patients Treated with Pantheris Prior to Antirestenotic Therapy

      Avinger, Inc. (NASDAQ: AVGR ), a leading developer of image-guided, catheter-based systems for the diagnosis and treatment of patients with Peripheral Artery Disease (PAD), today announced the publication of very promising clinical outcomes data from a study evaluating the performance of the Pantheris® Lumivascular atherectomy system combined with antirestenotic therapy in the treatment of PAD. This retrospective single-center, single-arm study has been published in the April 2019 issue of the peer-reviewed Journal of Cardiovascular Surgery under the title "Optical Coherence Tomography Guided Directional Atherectomy with Antirestenotic Therapy for Femoropopliteal Arterial Disease." The study analyzed the clinical outcomes of 33 patients (37 ...

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    6. Perimeter Medical Imaging Inc Announces 510(k) Clearance by FDA

      Perimeter Medical Imaging Inc Announces 510(k) Clearance by FDA

      Perimeter Medical Imaging, Inc. (“Perimeter Medical”) announced today that the company received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market the second generation of their platform imaging tool used in the evaluation of human tissue microstructure by providing two-dimensional, cross-sectional, real-time depth visualization. Enhancements to the newly cleared OTIS™ 2.0 system over the previous generation include: A novel specimen positioning consumable feature Touchscreen interface with improved software, designed to streamline integration with existing clinical workflow 10x faster image acquisition speed Perimeter has developed a world class proprietary reference atlas, with correlations between OTIS ...

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    7. Post-doctoral Adaptive Optics Research Fellow at U.S. Food and Drug Administration

      Post-doctoral Adaptive Optics Research Fellow at U.S. Food and Drug Administration

      Seeking a highly motivated post-doctoral Adaptive Optics Research Fellow to work at the U.S. Food and Drug Administration, Center for Devices and Radiological Health. The candidate will work in the Division of Biomedical Physics under the direction of Drs. Zhuolin Liu and Daniel X. Hammer and perform research with the FDA multimodal adaptive optics (mAO) imager. The FDA mAO imaging system allows visualization of different retinal cells, including ganglion cells, retinal pigment epithelial cells, and photoreceptors. The candidate will be expected to: conduct human imaging in healthy and diseased eyes, perform data processing, analysis and presentation, develop new and ...

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    8. University of Iowa Receives NIH Grant for Choroidal Disease Mechanisms in AMD

      University of Iowa Receives NIH Grant for Choroidal Disease Mechanisms in AMD

      University of Iowa Receives a 2019 NIH Grant for $381,250 for Choroidal Disease Mechanisms in AMD. The principal investigator is Elliott Sohn. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. We propose to investigate the pathophysiology of choroidal degeneration in age-related macular degeneration (AMD), the most common form of untreatable central vision loss in the western world. The choroid, the complex vascular system supplying the outer retina, photoreceptors, and retinal pigment epithelium (RPE), can now be visualized in living humans using enhanced depth imaging optical coherence tomography (OCT). Recent studies ...

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    9. Northwestern University Receives NIH Grant for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography.

      Northwestern University Receives NIH Grant  for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography.

      Northwestern University Receives a 2019 NIH Grant for $39,955 for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography. The principal investigator is Brian Soetikno. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. The retina is one of the most metabolically active tissues in the human body, making it particularly susceptible to hypoxia. In diabetic retinopathy (DR), aberrant oxygen metabolism has been hypothesized to play a pivotal role its pathogenesis. An improved understanding of how imbalances in oxygen delivery and demand lead to the progression of DR ...

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    10. University of Southern California Receives NIH Grant for Understanding Otoacoustic Emissions

      University of Southern California Receives NIH Grant for Understanding Otoacoustic Emissions

      University of Southern California Receives a 2019 NIH Grant for $487,053 for Understanding Otoacoustic Emissions. The principal investigator is Christopher Shera. The program began in 1999 and ends in 2024. Below is a summary of the proposed work. Realizing the potential of otoacoustic emissions (OAEs) as noninvasive probes of cochlear function requires understanding the physical and physiological mechanisms that generate and shape these sounds. To address important unresolved issues of cochlear mechanics while improving our understanding of OAE generation, we propose three aims involving innovative theoretical modeling rigorously tested by experimental measurements. The first Aim studies the action of ...

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    11. University of Washington Receives NIH Grant for Optical Coherence Elastography of Corneal Dyanamics

      University of Washington Receives NIH Grant for Optical Coherence Elastography of Corneal Dyanamics

      University of Washington Receives a 2019 NIH Grant for $560,406 for Optical Coherence Elastography of Corneal Dyanamics. The principal investigator is Sueng Shen. The program began in 2016 and ends in 2021. Below is a summary of the proposed work. The cornea is a highly organized, layered (lamellae) structure of collagen fibrils providing both high tensile strength to protect the eye and 70% of it refractive power. Although physical properties are closely linked to its primary optical function, its response to surgical interventions, and the results of routine eye tests such as intraocular pressure measurements, corneal biomechanics has not ...

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    12. University of Southern California Receives NIH Grant for Optical Coherence Tomography for 3D Measures of Cochlear Mechanics In Vivo

      University of Southern California Receives NIH Grant for Optical Coherence Tomography for 3D Measures of Cochlear Mechanics In Vivo

      University of Southern California Receives a 2019 NIH Grant for $408,735 for Optical Coherence Tomography for 3D Measures of Cochlear Mechanics In Vivo. The principal investigator is John Oghalai. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. The function of the cochlea is to transduce complex sound pressure waves into electrical signals. Organ of Corti vibration is based upon a complex interplay between passive mechanical structures and active OHC- based processes. While laser Doppler vibrometry has added tremendously to our understanding of cochlear physiology, this technique is limited. Only motion ...

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    13. Indiana University Receives NIH Grant for Imaging Spatial and Temporal dynamics of Retinal Ganglion Cells

      Indiana University Receives NIH Grant for Imaging Spatial and Temporal dynamics of Retinal Ganglion Cells

      Indiana University Receives a 2019 NIH Grant for $452,718 for Imaging Spatial and Temporal dynamics of Retinal Ganglion Cells. The principal investigator is Donald Miller. The program began in 2019 and ends in 2023. Below is a summary of the proposed work. Ganglion cells (GCs) and other inner retinal neurons are fundamental to retinal neural circuitry, processing photoreceptor signals relayed from intermediate neurons for transmission to the brain. Yet, much remains unknown about their role in vision and their vulnerability to disease leading to blindness. GCs in particular are lost to neurodegenerative disorders such as glaucoma, Alzheimer’s disease ...

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    14. University of Houston Receives NIH Grant for Structural and Molecular Phenotyping of Embryonic Development Through Multi-Modal Optical Imaging

      University of Houston Receives NIH Grant for Structural and Molecular Phenotyping of Embryonic Development Through Multi-Modal Optical Imaging

      University of Houston Receives a 2019 NIH Grant for $676,224 for Structural and Molecular Phenotyping of Embryonic Development Through Multi-Modal Optical Imaging. The principal investigator is David Mayerich The program began in 2019 and ends in 2024. Below is a summary of the proposed work. The ability to correlate between large-scale developmental milestones and micro-scale cellular and protein- specific changes is a significant unmet need in the study of developmental biology. The overall objective of this work is to develop a multi-modality imaging platform that can provide time resolved three-dimensional images of tissue development, with high temporal and spatial ...

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    15. University of Alabama at Birmingham Receives NIH Grant for African Decent and Glaucoma Evaluation (ADAGES) IV: Alternations of the Lamina Cribrosa in Progression

      University of Alabama at Birmingham Receives NIH Grant for African Decent and Glaucoma Evaluation (ADAGES) IV: Alternations of the Lamina Cribrosa in Progression

      University of Alabama at Birmingham Receives a 2019 NIH Grant for $635,960 for African Decent and Glaucoma Evaluation (ADAGES) IV: Alternations of the Lamina Cribrosa in Progression. The principal investigator is Massimo Fazio. The program began in 2017 and ends in 2021. Below is a summary of the proposed work. This proposal is focused on morphological changes in the lamina cribrosa with glaucoma onset and progression, and how those changes impact visual function, with a focus on racial disparities. This project leverages on the longitudinal monitoring of a subset of glaucoma patients in the existing ADAGES cohort of which ...

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    16. University of Southern California Receives NIH Grant for Influence of Hair Bundle Properties on Cochlear Mechanics

      University of Southern California Receives NIH Grant for Influence of Hair Bundle Properties on Cochlear Mechanics

      University of Southern California Receives a 2019 NIH Grant for $63,746 for Influence of Hair Bundle Properties on Cochlear Mechanics. The principal investigator is James Dewey The program began in 2017 and ends in 2020. Below is a summary of the proposed work. Normal hearing depends on the delicate mechanotransduction apparatus of inner ear hair cells – the stereociliary hair bundle. Cochlear vibrations deflect the hair bundle, which converts mechanical stimulation to electrical signals via gating of mechanosensitive ion channels. Hair bundle transduction is critical for hearing, as it is required for afferent signaling by inner hair cells, and for ...

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    17. University of Southern California Receives NIH Grant for Optical Imaging Technologies to Identify Residual Cholesteatoma and Improve Ossiculoplasty Outcomes

      University of Southern California Receives NIH Grant for Optical Imaging Technologies to Identify Residual Cholesteatoma and Improve Ossiculoplasty Outcomes

      University of Southern California Receives a 2019 NIH Grant for $670,541 for Optical Imaging Technologies to Identify Residual Cholesteatoma and Improve Ossiculoplasty Outcomes. The principal investigator is Brian Applegate. The program began in 2019 and ends in 2022. Below is a summary of the proposed work. There are a number of diseases and conditions in the middle ear that cause hearing loss in both children and adults. In children it is particularly important to expedite interventions to restore hearing since it negatively impacts language development and academic performance. An example is cholesteatoma, a benign lesion due to abnormal skin ...

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    18. PhD Studentship in Biomedical Optics and Retinal Imaging at The University of Illinois at Chicago

      PhD Studentship in Biomedical Optics and Retinal Imaging at The University of Illinois at Chicago

      A PhD position is available in the Biomedical Optics and Functional Imaging group within the Department of Bioengineering, University of Illinois at Chicago. Our research lab is working on ultra-wide field fundus photography, functional optical coherence tomography (OCT), OCT angiography (OCTA), super-resolution ophthalmoscopy, retinal image analysis and classification ( https://yaolab.bioe.uic.edu/ ). The PhD student will be involved for imaging instrument development and/or experimental study of retinal morphology & physiology. The specific study plan of the student can be flexible based on his/her education background and interest. The successful candidate should have a BS/MS degree in Optical ...

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      Mentions: Xincheng Yao
    19. Feature Of The Week 03/31/2019: Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue

      Feature Of The Week 03/31/2019: Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue

      We have developed a multimodal laser scanning microscope (LSM) platform combining optical coherence tomography (OCT), spectral focusing coherent anti-Stokes Raman scattering (SF-CARS), second harmonic generation (SHG) and two-photon excited fluorescence (TPF). Morphological, molecular and biochemical information from tissues can be collected in a non-invasive and label-free manner by merging ultra-fast Ti:sapphire lasers with well-developed optical imaging techniques. The combination of the proposed imaging modalities enables increased sensitivity and specificity for detection of early tissue alteration related to pathological condition and may offer novel insights in the diagnosis of diseases. OCT is fused with nonlinear optical microscopy techniques to perform ...

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    20. Postdoc in Optics and Biophotonics in the Department of Physical Chemistry of Biological Systems at the Polish Academy of Sciences

      Postdoc in Optics and Biophotonics in the Department of Physical Chemistry of Biological Systems at the Polish Academy of Sciences

      We encourage applicants for Assistant professor (post-doc) position in the Department of Physical Chemistry of Biological Systems at Institute of Physical Chemistry PAS, Warsaw, Poland. This position is a part of the RETURNS project funded by the Polish National Agency For Academic Exchange (NAWA). The RETURNS Project is targeted at development of enhanced polarization contrast optical tomography to improve the outcomes of automatic localization and characterization of malignant tissue. Eligibility criteria: PhD degree in engineering, physics, computer science, mathematics, physiology, biology, or similar; Track record of achievements relative to opportunity; Experience (2-4 years) in at least one of: optical coherence ...

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      Mentions: Karol Karnowski
    21. Heidelberg Engineering Introduces the GMPE Hood Glaucoma Report for SPECTRALIS® OCT

      Heidelberg Engineering Introduces the GMPE Hood Glaucoma Report for SPECTRALIS® OCT

      New feature of the Glaucoma Module Premium Edition offers an intuitive and accurate approach to aid diagnosis and management of glaucoma Heidelberg Engineering, a privately-held imaging and healthcare IT technologies company focused on ophthalmic diagnostic solutions that empower clinicians to improve patient care, announced today that the Hood Glaucoma Report is now available with a software update within the SPECTRALIS OCT Glaucoma Module Premium Edition (GMPE).” The GMPE Hood Glaucoma Report highlights essential diagnostic information in an intuitive layout that enables a quick, yet comprehensive assessment. Based on the diagnostic approach developed by Donald C. Hood, PhD, this report also ...

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    22. David Huang Listed on Ophthalmologist Magazine's 2019 Power List as #1 Inventor!

      David Huang Listed on Ophthalmologist Magazine's 2019 Power List as #1 Inventor!

      We are delighted to share The Ophthalmologist’s Power List 2019 with you. This year saw a record number of nominations – almost 2,000 – across five categories: Champions for Change, Inventors, Emerging Leaders, Mentors, and Surgical Pioneers. Each nomination celebrates an individual who has made a significant impact on the field, whether that is through a philanthropic initiative or their ongoing commitment to innovation. The diversity of the categories – and the huge influx of votes – have brought in many new names. In fact, half of this year’s Power Listers have not been featured before. And 16 of the front-runners ...

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    23. Postdoctoral opening in retinal imaging instrumentation within the Department of Bioengineering, University of Illinois at Chicago

      Postdoctoral opening in retinal imaging instrumentation within the Department of Bioengineering, University of Illinois at Chicago

      A postdoctoral position is available in the Biomedical Optics and Functional Imaging group ( https://yaolab.bioe.uic.edu ) within the Department of Bioengineering, University of Illinois at Chicago. Our research lab is working on ultra-wide field fundus photography, functional optical coherence tomography (OCT), super-resolution ophthalmoscopy, retinal image analysis and classification. The postdoctoral fellow will be responsible for instrument development and retinal study. The successful candidate should have a Ph.D. degree in Optical Engineering, Electrical Engineering, Applied Physics or a related discipline. Experience with optical design and construction is essential. Proficiency in Labview and Matlab programming is expected. Hand-on experience ...

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      Mentions: Xincheng Yao
    24. NinePoint Medical Receives NIH Grant for An Integrated Optical Coherence Tomography and Tissue Acquisition Device for Diagnostics of Indeterminate Biliary Strictures

      NinePoint Medical Receives NIH Grant for An Integrated Optical Coherence Tomography and Tissue Acquisition Device for Diagnostics of Indeterminate Biliary Strictures

      NinePoint Medical Receives a 2019 NIH Grant for $222,020 for An Integrated Optical Coherence Tomography and Tissue Acquisition Device for Diagnostics of Indeterminate Biliary Strictures. The principal investigator is Eman Namati. The program began in 2019 and ends in 2020. Below is a summary of the proposed work. Bile duct strictures can lead to painful clinical symptoms and can be caused by a wide range of conditions from benign diseases to cholangiocarcinoma, a deadly cancer of the bile duct with 5-year survival rates as low as 2% for late stage disease. The management and prognosis of bile duct strictures ...

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