1. Optical Coherence Tomography News

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    1. Feature Of The Week 4/13/14: Growth Kinetics of Concave Nanocubes Studied by Optical Coherence Tomography

      Feature Of The Week 4/13/14: Growth Kinetics of Concave Nanocubes Studied by Optical Coherence Tomography

      This work presents the analysis of the growth kinetics of two syntheses of concave gold nanocubes with a mean size of 72 and 108 nm followed by the optical coherence tomography (OCT) technique by acquiring B-scan images each 5 s. In addition, ultra violet-visible (UV-Vis) spectra and mean size from dynamic light scattering (DLS) were acquired during nanoparticle growth to generate kinetic plots in order to corroborate the OCT results. Kinetic plots from OCT images were obtained by plotting contrast enhancement of B-scan images as function of time. Fitting parameters values given by using the classical Kolmogorov-Johnson-Mehl-Avrami (KJMA) equation show ...

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    2. Postdoctoral Associate Position in Biophotonics at Stanford University

      Postdoctoral Associate Position in Biophotonics at Stanford University

      The Stanford Biomedical Optics Group (PI: Audrey K Ellerbee), in collaboration with clinical researchers in the School of Medicine (urology and embryology), seeks highly motivated postdoctoral candidates with a strong experimental background and solid theoretical preparation in optics, microscopy, medical imaging and image processing. Stanford University provides an outstanding environment for solid technical research with clinical impact. A postdoctoral position is available related to active research in the following areas: optical coherence tomography, endoscopic probe development, spectroscopy. Start date: Immediate. Term: Up to 2 years. Requirements: Applicants should have received a Ph.D. in Electrical Engineering, Physics / Applied Physics, Optics ...

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    3. UC Davis Receives a NIH Grant for studying Structure and Function of The Chorioretinal Complex in Age-Related Macular Degeneration.

      UC Davis Receives a NIH Grant  for studying Structure and Function of The Chorioretinal Complex in Age-Related Macular Degeneration.

      University of California at Davis Receives a 2014 NIH Grant for $563,632 for studying Structure and Function of The Chorioretinal Complex in Age-Related Macular Degeneration. The principal investigator is John Werner. The program began in 2014 and ends in 2019. Below is a summary of the propose work. Three aims are proposed to study the chorioretinal complex (choroid, choriocapillaris, Bruch's membrane, retinal pigment epithelium, photoreceptors) in age-related macular degeneration (AMD). Each aim includes both technical goals involving optical imaging and tests of hypotheses related to the pathogenesis of this disease. Aim 1 will use phase changes between successive ...

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    4. MGH Receives NIH Grant for Development of a Preclinical Optical Frequency Domain Angiography Instrument

      MGH Receives NIH Grant for Development of a Preclinical Optical Frequency Domain Angiography Instrument

      Massachusetts General Hospital Receives a 2014 NIH Grant for $467,429 for Development of a Preclinical Optical Frequency Domain Angiography Instrument. The principal investigator is Benjamin Vakoc. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Tumor-induced angiogenesis plays a central role in the progression of tumors to malignancy, provides the critical transport of blood-born therapies into the tumor space, and supplies oxygen to effectuate oxygen-dependent radiological and light-based therapies. Pre-clinical research in tumor angiogenesis and tumor microvascular function has traditionally relied on histological methods, which suffer from well-known limitations, or fluorescence-based ...

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    5. Oregon Health & Science University Receives NIH grant to study Dynamic Changes in the Chick Developing Heard in Response to Altered Hemodyanmics

      Oregon Health & Science University Receives NIH grant to study Dynamic Changes in the Chick Developing Heard in Response to Altered Hemodyanmics

      Oregon Health & Science University received at 2014 NIH grant for $404,161 to study Dynamic Changes in the Chick Developing Heard in Response to Altered Hemodyanmics. The principal investigator is Sandra Rugonyi. The program began in 2008 and ends in 2015. Below is a summary of the proposed work. About 1% newborn babies have congenital heart disease (CHD), the leading cause of death among children. The majority of CHD cases are believed not to have a genetic cause. Other factors, such as abnormal blood flow during embryonic and fetal stages can lead to heart malformations and thus CHD through poorly ...

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    6. UCSF Receives NIH Grant for Selective Ablation of Dental Caries and Composites

      UCSF Receives NIH Grant for Selective Ablation of Dental Caries and Composites

      The University of California at San Francisco received a 2014 NIH Grant for $394,375 for Selective Ablation of Dental Caries and Composites. The principal investigator is Daniel Fried. The program began in 2009 and ends in 2018. below is a summary of the proposed work. The overall objective of this proposed research is to increase our fundamental understanding of the interaction of high intensity laser radiation with dental hard tissues and apply that knowledge to the development of laser based methods that selectively remove dental caries and composite restorative materials using an integrated approach of computer-controlled laser beam scanning ...

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    7. Physical Sciences Receives NIH Grant for A Functional Otoscopy for Non-Invasive Diagnosis of Middle Ear

      Physical Sciences Receives NIH Grant for A Functional Otoscopy for Non-Invasive Diagnosis of Middle Ear

      Physical Sciences Received at 2014 NIH Grant for $197,522 for A Functional Otoscopy for Non-Invasive Diagnosis of Middle Ear. The principal investigator is Ernest Chang. The program begins and ends in 2014. Below is a summary of the proposed work. There is a growing clinical need for improving the non-invasive diagnostic capabilities of middle ear pathologies in vivo. To address this need, Physical Sciences Inc. (PSI), in collaboration with the Eaton Peabody Lab at the Massachusetts Eye and Ear Infirmary (MEEI), will develop a clinically viable otoscopic imaging system that will employ phase sensitive optical coherence tomography (OCT) to ...

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    8. Georgetown University Receives NIH Grant for Non-Invasive Evaluation of Transplant Kidney Using OCT

      Georgetown University Receives NIH Grant for Non-Invasive Evaluation of Transplant Kidney Using OCT

      Georgetown University Received at 2014 NIH Grant for $520,754 for Non-Invasive Evaluation of Transplant Kidney Using OCT. The principal investigator is Peter Michael Andrewss. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. There is currently a worldwide shortage of kidneys for transplantation due mainly to the fact that there is no reliable means to determine their viability (i.e., kidneys stored for long periods of time, etc.). Also, following transplantation, kidneys oftn do not function immediately and their status is unclear. Previously, we have shown that the histopathology of living ...

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    9. Postdoctoral Research Fellowships in Optical Coherence Tomography at Wellman Center for Photomedicine Massachusetts General Hospital

      Postdoctoral Research Fellowships in Optical Coherence Tomography at Wellman Center for Photomedicine Massachusetts General Hospital

      A Postdoctoral research fellowship in the area of In Vivo Microscopy is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow at Harvard Medical School. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new in vivo microscopy technologies with applications in basic and clinical research. The fellowship will focus on the development and clinical application of advanced in vivo microscopy imaging ...

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    10. Bioptigen Introduces Image-Guided SDOCT Technology to Advance Preclinical Eye Research

      Bioptigen Introduces Image-Guided SDOCT Technology to Advance Preclinical Eye Research

      Bioptigen announced today the availability of EnFace TM color fundus technology delivering image-guided SDOCT into a single, compact, handheld scan head. The new color fundus system provides multiple, integrated modalities into each of Bioptigen’s Envisu TM preclinical SDOCT systems, producing brilliant, color fundus images captured simultaneously with OCT images. The new color image-guided OCT also complements Bioptigen’s volumetric OCT image visualization, and dynamic 3D tissue flattening capabilities to create a powerful, comprehensive suite of tools designed to meet the exacting needs of the ophthalmic research community. Bioptigen's new Envisu SDOCT scan head featuring integrated color fundus camera ...

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    11. St. Jude Medical Recognized as Innovative Technology Supplier of the Year by Nation’s Largest Health Care Contracting Organization

      St. Jude Medical Recognized as Innovative Technology Supplier of the Year by Nation’s Largest Health Care Contracting Organization

      St. Jude Medical, Inc . ( STJ ), a global medical device company, was recognized by Novation as the 2013 Innovative Technology Supplier of the Year. Novation members selected the St Jude Medical ILUMIEN™ PCI Optimization System based on their experience using the technology to deliver improved patient outcomes. Novation works with its more than 100,000 members and affiliates to identify innovative technology that improves patient care or reduces the risk of harm to patients or providers, while simultaneously raising the standard of patient care and safety. “Novation’s goals of improving patient outcomes through innovative technology align with our mission at ...

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    12. Imalux Ceases Operation

      Imalux Ceases Operation

      Imalux Corporation has announced that it has ceased operations due to various challenges to become a profitable on-going business. Imalux Corporation was one of the earliest OCT startup companies and received its first seed funding in 2000. Imalux opened operations in Cleveland Ohio with a strong technology connection to the Institute of Applied Physics in Russia. With the visionary leadership of Paul Amazeen and Felix Feldchtein Imalux developed the Niris product line that offered unique endoscopy imaging capabilities. Niris systems were delivered to customer's worldwide offering physicians the ability to identify structural changes in tissues, guide surgical interventions and ...

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    13. International Workshop on Tissue Phantoms and Standardization in Biophotonics at University of Maryland, May 21, 2014

      International Workshop on Tissue Phantoms and Standardization in Biophotonics at University of Maryland, May 21, 2014

      The primary objective of the proposed scientific exchange and conference program is to facilitate development of phantom-based test methods, build a foundation upon which rigorous, least burdensome consensus standards can be achieved and ensure FDA’s readiness to evaluate innovative and emerging optical imaging technologies. A number of key challenges will be addressed in the proposed workshop. Currently, there is a general lack of knowledge in the biophotonics field regarding international consensus standards, including their importance and the extent and type of effort required for their development. Greater understanding and appreciation will likely lead to an increase in the amount ...

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    14. NIDEK Announces FDA Clearance of the RS-3000 Advance

      NIDEK Announces FDA Clearance of the RS-3000 Advance

      NIDEK, Inc. a global leader in the design, manufacturing, and distribution of ophthalmic equipment, is pleased to announce FDA clearance of the RS-3000 Advance . This premier OCT system incorporating Scanning Laser Ophthalmoscope is designed for comprehensive evaluation of the retina and choroid. The RS-3000 Advance provides exquisite detail of the retinal and choroidal microstructures to assist in clinical diagnosis. Features include the choroidal mode, which allows detailed evaluation of the choroid. A wide area scan of 9 mm x 9 mm ensures excellent overall coverage of the retinal structures. Microsaccades and other involuntary eye movements are compensated by the Tracing ...

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    15. Postdoctoral Optical Engineer in Biomedical Optics at Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School

      Postdoctoral Optical Engineer  in Biomedical Optics at Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School

      Employer Description Postdoctoral research opportunities are available in the area of biomedical optics at the Massachusetts General Hospital in the Wellman Center for Photomedicine. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for the development of cutting edge technologies and their application in basic and clinical research. Job Description Postdoctoral / Optical Engineering positions (Biomedical Optics) Research opportunities are available in the area of biomedical optics at the Massachusetts General Hospital in the Wellman Center for Photomedicine. MGH’s role as a leading teaching affiliate ...

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    16. Feature Of The Week 4/2/14: A Compact High-Performance Hand-Held Device for Extending Ophthalmic OCT to New Points of Care (Narrated Presentation)

      Feature Of The Week 4/2/14: A Compact High-Performance Hand-Held Device for Extending Ophthalmic OCT to New Points of Care (Narrated Presentation)

      We developed an ultrahigh speed, handheld swept source optical coherence tomography (SS-OCT) ophthalmic instrument using a 2D MEMS mirror. A vertical cavity surface-emitting laser (VCSEL) operating at 1060 nm center wavelength yielded a 350 kHz axial scan rate and 10 µm axial resolution in tissue. The long coherence length of the VCSEL enabled a 3.08 mm imaging range with minimal sensitivity roll-off in tissue. Two different designs with identical optical components were tested to evaluate handheld OCT ergonomics. An iris camera aided in alignment of the OCT beam through the pupil and a manual fixation light selected the imaging ...

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    17. Madrid-MIT +Vision Consortium announces Fellowships in Translational Biomedical Imaging

      Madrid-MIT +Vision Consortium announces Fellowships in Translational Biomedical Imaging

      Madrid-MIT +Vision Consortium announces Fellowships in Translational Biomedical Imaging. Fellowships entail a training program in Madrid and Boston and development of collaborative projects between institutions in both cities. The Institute of Optics-CSIC (Madrid), as a member of the Consortium, encourages postdoctoral applications in the fields of optical ocular imaging within the frame of this program. Application deadline: April 30th 2014. Starting date: September 2th 2014. Full announcement: http://viobiolabs.wordpress.com/2014/03/14/2014-mvision-fellowship-call-for-applications/ More information on the Fellowship program: http://mvisionconsortium.mit.edu/fellowship Begin your application: https://app.hobsons.co.uk/?id=madrid-mit

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    18. Post-Doc in Disease Detection in OCT at the Medical University of Vienna, Austria

      Post-Doc in Disease Detection in OCT at the Medical University of Vienna, Austria

      The Computational Image Analysis Lab (CIR) and Vienna Reading Center (VRC) at the Medical University of Vienn a, Austria are seeking outstanding candidates for the following position in computer vision research in the field of retinal imaging:  Post-Doc - Disease Detection in Optical Coherence Tomography (2 years) Project description : You will work in an exciting, multi-year, government-funded interdisciplinary project at the interface of computer science, engineering and medicine. The project is embedded in a long-standing collaboration among a large group of researchers from computer vision, medical physics and ophthalmology. Participating institutions include VRC, CIR, the Iowa Institute for Biomedical Imaging at ...

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    19. MedLumics Announces “BiopsyPen Project” with €3.6M EU in Funding; Initiative Aimed at New Clinical Applications for Optical Coherence Tomography

      MedLumics Announces “BiopsyPen Project” with €3.6M EU in Funding; Initiative Aimed at New Clinical Applications for Optical Coherence Tomography

      MedLumics , a medical imaging company specializing in advanced optical coherence tomography (OCT) technology, today announced the kick off of a three-year initiative to translate the latest OCT research into new clinical applications. Called the “BiopsyPen Project,” the effort is led by MedLumics and the Medical University of Vienna, with participation from a consortium of European members including VTT Finland, Delft University of Technology, Exalos AG, the Polytechnic University of Madrid, and Optocap Ltd. Together, the organizations are working to develop the second generation of a compact handheld diagnostic imaging system that will radically transform the capability of biophotonic technologies for ...

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    20. Positive top line results from clinical trial for diagnosis of basal cell carcinoma using VivoSight OCT

      Positive top line results from clinical trial for diagnosis of basal cell carcinoma using VivoSight OCT

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, announces positive top line results from the successfully completed multi-centre, prospective clinical trial for the diagnosis of basal cell carcinoma using VivoSight OCT. In the study, over 250 patients with clinically suspicious lesions for basal cell carcinoma were scanned at six centres in Germany. In each case, diagnosis using VivoSight OCT was compared with standard clinical diagnosis with and without dermoscopy. All results were verified by the gold standard of biopsy and histological analysis. Papers by Professor Dr. med. Julia Welzel, Dr. med. Martina ...

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    21. University of Miami Receives NIH Grant for Advanced Imaging for Diabetic Retinopathy

      University of Miami Receives NIH Grant for Advanced Imaging for Diabetic Retinopathy

      The University of Miami Received a 2014 NIH Grant for $367,808 for Advanced Imaging for Diabetic Retinopathy. The principal investigator is Delia Cabrera Debuc. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Diabetic retinopathy (DR) is a major cause of visual loss in diabetic individuals that presents a significant diagnostic challenge. Advances in preventing vision loss in these individuals are hindered by limited understanding of mechanisms underlying DR and the altered relationships between the retinal neural tissue and retinal vasculature. Therefore, an objective test for the early diagnosis and evaluation ...

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    22. Feature Of The Week 3/23/14: Tambov State Technical University Investigates One Specific Velocity Color Mapping One Specific Velocity Color Mapping

      Feature Of The Week 3/23/14: Tambov State Technical University Investigates One Specific Velocity Color Mapping One Specific Velocity Color Mapping

      The method of sign-sensitive mapping of the given range of velocities in a flow with complex geometry based on the principles of optical coherence tomography is described. To produce an alternating-sign flow, the 1% aqueous intralipid solution and the tilted capillary entry with the contraction coefficient 4:1 are used. The mapping is controlled using two parameters, the value of one specific velocity (OSV) for mapping and the accuracy of its determination. The structure image and two OSV images (for positive and negative direction of motion) are obtained as a result of selecting and processing the relevant parts of the ...

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    23. PhD Student Position: design, fabrication and control of 2-axis endoscopic MOEMS scanner and implementation in an endomicroscopy microsystem for early diagnosis of cancer FEMTO-ST, Besançon, France

      PhD Student Position: design, fabrication and control of 2-axis endoscopic MOEMS scanner and implementation in an endomicroscopy microsystem for early diagnosis of cancer FEMTO-ST, Besançon, France

      PhD Student Position: design, fabrication and control of 2-axis endoscopic MOEMS scanner and implementation in an endomicroscopy microsystem for early diagnosis of cancer The FEMTO-ST Institute (CNRS unit), associated with the Université de Franche-Comté (UFC), announces the opening of a PhD Student position in design and fabrication of Biophotonic Microsystems. This position, delivering a PhD diploma of UFC, is starting from October 1, 2014. The position is proposed in the frame of a joint collaboration between FEMTO-ST/UFC and Department of Electrical and Computer Engineering/University of Florida (UF), and includes a stage of 18 months at UF, Florida. FEMTO-ST ...

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    24. PhD scholarship in MEMS Tunable VCSELs for Optical Coherence Tomography at Technical University of Denmark

      PhD scholarship in MEMS Tunable VCSELs for Optical Coherence Tomography at Technical University of Denmark

      Applications are invited for a 3-year PhD position within the field of MEMS tunable VCSELs for optical coherence tomography (OCT). The project is multidisciplinary and will cover topics within the field of semiconductor optical devices, microelectromechanical systems, semiconductor technology and optical measurement systems. The project will be carried out at the Department of Photonics, Technical University of Denmark (DTU). Fast and widely tunable VCSELs are set to revolutionize the applications of tunable lasers for sensing. They promise not only low cost but also new properties like high dynamic coherence not normally associated with fast tunable lasers. Impressive results have been ...

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