1. Optical Coherence Tomography News

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    1. NASA presents Heidelberg Engineering the NASA Certificate of Appreciation

      NASA presents Heidelberg Engineering the NASA Certificate of Appreciation

      Heidelberg Engineering was honored today by visitors from NASA. The guests from NASA: Dr. Christian Otto, Lead Scientist for the Vision Impairment and Intracranial Pressure (VIIP) project ; Dr. Steven Hart, lead flight surgeon for VIIP ; Rachel Brady, VIIP Science Coordinator; and Jennifer Villarreal, Project Manager came for a ceremony to present Heidelberg Engineering with the NASA Certificate of Appreciation in recognition of Heidelberg Engineering’s support in placing a SPECTRALIS ® OCT system on the International Space Station (ISS). During the ceremony, the NASA guests described the physiological challenges encountered with long duration space flight and the research underway to understand ...

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    2. Real-time OCT guidance of an ablation laser for advancement in the fight of atherosclerotic cardio-vascular disease

      Real-time OCT guidance of an ablation laser for advancement in the fight of atherosclerotic cardio-vascular disease

      Real-time OCT guidance of an ablation laser has now been developed for use in the treatment of atherosclerotic cardio-vascular disease. DWH Systems, Inc. of Seminole Florida working with ELAN Vascular Technologies has developed a system whereby three OCT imaging heads monitor a femtosecond ablation laser in real-time, to perform micro ablation on the outer surface of diseased arteries. OCT is used first to acquire a 3D, C-scan map of the diseased portion of an artery then develops an ablation map for the system to follow. As ablation is performed, OCT again monitors the lasers cutting process from multiple angles in ...

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    3. Feature Of The Week 02/22/15: Case Western Reserve University Demostrates Using OCT to Rapidly Phenotype and Quantify Congenital Heart Defects Associated with Prenatal Alcohol Exposure

      Feature Of The Week 02/22/15:  Case Western Reserve University Demostrates Using OCT to Rapidly Phenotype and Quantify Congenital Heart Defects Associated with Prenatal Alcohol Exposure

      The most commonly used method to analyze congenital heart defects involves serial sectioning and histology. However, this is often a time-consuming process where the quantification of cardiac defects can be difficult due to problems with accurate section registration. Here we demonstrate the advantages of using optical coherence tomography, a comparatively new and rising technology, to phenotype avian embryo hearts in a model of Fetal Alcohol Syndrome where a binge-like quantity of alcohol/ethanol was introduced at gastrulation. The rapid, consistent imaging protocols allowed for the immediate identification of cardiac anomalies, including ventricular septal defects and misaligned/missing vessels. Interventricular septum ...

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    4. University of Miami Receives NIH Grant for Advanced Imaging for Diabetic Retinopathy

      University of Miami Receives NIH Grant  for Advanced Imaging for Diabetic Retinopathy

      University of Miami Receives a 2015 NIH Grant for $155,387 for Advanced Imaging for Diabetic Retinopathy. The principal investigator is Delia Cabrera Debuc. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Diabetic retinopathy (DR) is a major cause of visual loss in diabetic individuals that presents a significant diagnostic challenge. Advances in preventing vision loss in these individuals are hindered by limited understanding of mechanisms underlying DR and the altered relationships between the retinal neural tissue and retinal vasculature. Therefore, an objective test for the early diagnosis and evaluation of ...

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    5. Michelson Diagnostics closes £2.5 million First Tranche of £4.0 million Series B fundraising Smith & Nephew as Cornerstone Investor

      Michelson Diagnostics closes £2.5 million First Tranche of £4.0 million Series B fundraising Smith & Nephew as Cornerstone Investor

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, is pleased to announce that it has closed the £2.5 million First Tranche of its Series B financing. This was led by strategic investor, global medical technology business Smith & Nephew and included new investor Kent County Council as well as existing investors. The £2.5 million investment will be used to expand the Michelson Diagnostics’ commercial presence in Germany; launch the Company’s next generation VivoSight OCT tissue-imaging system; complete the ongoing US multi-centre clinical biopsy avoidance study and explore further applications of ...

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    6. Feature Of The Week 02/15/15: Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Feature Of The Week 02/15/15: Optical Coherence Tomography Identifies Lower Labial Salivary Gland Surface Density in Cystic Fibrosis

      Cystic fibrosis (CF) is a genetic disease that affects multiple organs due to the production of abnormally viscous mucus. Recurring pulmonary infections result in build-up of lung damage which leads to death. Intestinal, pancreatic, and hepatobiliary complications also occur, further aggravating the course of the disease. The molecular basis of CF is the dysfunction of the CF transmembrane conductance regulator (CFTR). CFTR-related disruption of transmembrane ion transport affects the exocrine glands, among which are the labial salivary glands (LSGs). Optical coherence tomography (OCT) enables non-invasive visualization of the internal structures of tissues at micrometer resolution in vivo and in real ...

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    7. Smith & Nephew bets on technology that 'sees through the skin'

      Smith & Nephew bets on technology that 'sees through the skin'

      Smith & Nephew has bet on a new technology that enables doctors to "see through the skin", in the hope that it could be used by the company's growing wound care business. The med tech giant has invested £1.25m in Michelson Diagnostics, a small Kent-based business which uses laser beams to produce high resolution images of cells beneath the surface of the skin. Michelson's Vivosight system is already being used in place of biopsies to diagnose non-melanoma skin cancer , a less aggressive but more common variety of the disease compared with more deadly melanoma skin cancers. But the ...

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    8. University of Washington Receives NIH Grant to Study Non-invasive Real-Time Label-Free 3D Imaging of Retinal Microcirculation.

      University of Washington Receives NIH Grant to Study Non-invasive Real-Time Label-Free 3D Imaging of Retinal Microcirculation.

      University of Washington Received a 2015 NIH Grant to Study Non-invasive real-time label-free 3D imaging of retinal microcirculation. The principal investigator is Ruikang Wang. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. Non-invasive and label-free imaging techniques for assessing retinal blood perfusion in humans - down to capillary-level resolution, are of paramount importance for improved understanding, diagnosis, treatment and management of diseases that have a vascular component in their pathogenesis, e.g., age related macular degeneration (AMD), diabetic retinopathy (DR), and open angle glaucoma (OAG). Invasive imaging techniques, e.g., fluorescein angiography ...

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    9. Medical College of Wisconsin Receives NIH Grant to study Inhibition of Reflux-Induced Esophageal Adenocarinoma by Proanthocyanidins.

      Medical College of Wisconsin Receives NIH Grant  to study Inhibition of Reflux-Induced Esophageal Adenocarinoma by Proanthocyanidins.

      Medical College of Wisconsin Received a 2015 NIH Grant for $317,475 to study Inhibition of Reflux-Induced Esophageal Adenocarinoma by Proanthocyanidins. The prinipal investigator is Laura Kreesty. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Esophageal adenocarcinoma (EAC) rates have increased 500% over the last three decades resulting in EAC being identified as the fastest increasing of all cancer types in the US. Esophageal cancer is an extremely deadly malignancy with 5-year survival rates consistently under 20%. The precise reasons for increasing rates of EAC are an active area of investigation ...

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    10. Emanuel Hospital and Health Center Receives NIH Grant for Optical Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital and Health Center Receives NIH Grant  for Optical Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital and Health Center Received a 2015 NIH Grant for $553,852 for Optical Nerve Head SD-OCT Imaging in Glaucoma. The principal investigator is Claude Burgoyne. The program begain in 2010 and ends in 2019. Below is a summary of the proposed work. As a result of discoveries made during the first project period, we propose a paradigm change for clinical assessment of the Optic Nerve Head (ONH), peripapillary retinal nerve fiber layer (RNFL) and macula based on acquisition and regionalization of Spectral Domain Optical Coherence Tomography (SDOCT) ONH, RNFL and macula datasets relative to the axis between the ...

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    11. Haag-Streit UK Unveils 2 Products from the Optovue Portfolio at 100% Optical

      Haag-Streit UK Unveils 2 Products from the Optovue Portfolio at 100% Optical

      Optovue products, the iScan and iFusion, at 100% Optical. Haag-Streit UK (HS-UK), the newly-appointed Optovue UK distributor, unveiled 2 Optovue products, the iScan and iFusion , at 100% Optical.

      The fully-automated iScan is easy-to-use and requires minimal training. It has a small footprint and is ideal for a range of clinical settings. The fully-integrated system includes a full suite of retina, optic nerve and anterior segment scans with normative database comparison. It detects the eye to be scanned, aligns the camera over the pupil and optimises the scan's signal strength. After completing scan acquisition, iScan evaluates each scan to ensure ...

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    12. Optovue Introduces Two New Configurations of Software-Assisted OCT Device

      Optovue Introduces Two New Configurations of Software-Assisted OCT Device

      Optovue, a pioneer in spectral-domain optical coherence tomography (SD-OCT), announced that it has launched two new configurations of its iScan TM software-assisted OCT system: iScan Essential and iScan Comprehensive. The two product configurations are intended to give practitioners a choice in how they bring OCT technology into their practices. Both iScan Essential and iScan Comprehensive were created to simplify OCT technology, thus making it accessible to a range of eye care professionals in any practice setting. iScan's software-assisted platform vocally guides the patient through the entire exam and requires minimal operator involvement. The system's compact footprint and tabletop ...

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      Mentions: Optovue OptiScan
    13. ARVO to host Imaging in the Eye Conference in May 2015

      ARVO to host Imaging in the Eye Conference in May 2015

      The Association for Research in Vision and Ophthalmology (ARVO) will be hosting its annual Imaging in the Eye Conference on Saturday, May 2, 2015 in Denver, CO. This one-day conference takes place the day before the ARVO Annual Meeting. The conference brings together leading basic researchers, clinicians and engineers in the ophthalmic imaging field. Attendees can meet colleagues who are specialists in technology development, small animal imaging, image processing, translational research, clinical studies and clinical care in this rapidly changing area of research. The Imaging Conference highlights advances in many imaging techniques including optical coherence tomography (OCT), adaptive optics (AO ...

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    14. Voxeleron Releases Orion, Advanced OCT Analysis Software

      Voxeleron Releases Orion, Advanced OCT Analysis Software

      Orion™ is an application that offers fully-automated, rapid and accurate segmentation of seven layers in OCT images of the human retina. Currently for research use only, the award-winning software is platform independent - meaning it processes data from different OCT devices - and is now available following extensive beta testing. “We used Orion to process a considerable amount of data and found it to be a very useful research tool. The analysis tools that come with some of the OCT devices do not offer the functionality we need to do some of our fundamental clinical research, so Orion is a very powerful ...

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    15. PhD scholarship in Image Processing Software for Optical Coherence Tomography systems Technical University of Denmark

      PhD scholarship in Image Processing Software for Optical Coherence Tomography systems Technical University of Denmark

      The Fiber Sensors & Supercontinuum Group at DTU Fotonik, Department of Photonics Engineering at the Technical University of Denmark is seeking a PhD student for a 3-year Scholarship in the field of image processing software for Optical Coherence Tomography (OCT) systems operating in the mid-infrared. The position is funded by the project “Spectrally shaped supercontinuum sources for high-resolution Optical Coherence Tomography medical imaging and non-destructive testing” (ShapeOCT). Summary of the project ShapeOCT ShapeOCT will use Danish strongholds in supercontinuum (SC) light source and photonic crystal fiber (PCF) technology to develop a new generation of SC light sources with shaped noise and ...

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    16. Postdoc in mid-infrared Optical Coherence Tomography Systems at the Technical University of Denmark

      Postdoc in mid-infrared Optical Coherence Tomography Systems at the Technical University of Denmark

      The Fiber Sensors & Supercontinuum Group at DTU Fotonik, Department of Photonics Engineering at the Technical University of Denmark is seeking a candidate for a 4-year Postdoc position in the field of Optical Coherence Tomography (OCT) system operating in the mid-infrared. The position is funded by the project “Spectrally shaped supercontinuum sources for high-resolution Optical Coherence Tomography medical imaging and non-destructive testing” (ShapeOCT). Summary of the project ShapeOCT ShapeOCT will use Danish strongholds in supercontinuum (SC) light source and photonic crystal fiber (PCF) technology to develop a new generation of SC light sources with shaped noise and power spectra that are ...

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    17. Horizon Technology Finance Leads $15 Million Venture Loan Facility for NinePoint Medical

      Horizon Technology Finance Leads $15 Million Venture Loan Facility for NinePoint Medical

      Horizon Technology Finance Corporation ("Horizon") ( HRZN ), a leading specialty finance company that provides capital in the form of secured loans to venture capital backed companies in the technology, life science, healthcare information and services, and cleantech industries, today announced it has led a $15 million venture loan facility for NinePoint Medical, Inc. ("NinePoint"), an emerging leader in the development of medical devices for advanced optical imaging. NinePoint will use the proceeds for working capital purposes. Horizon funded an initial $5 million of its $7.5 million commitment under the venture loan facility. "We are pleased to lead a $15 million ...

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    18. Santec offers Electrically Pumped Tunable VCSEL HSL-1

      Santec offers Electrically Pumped Tunable VCSEL HSL-1

      Product Name: Tunable VCSEL Production code: HSL-1 Santec, a leading manufacturer of tunable lasers, optical instruments, and fiber-optic components, introduces the latest addition to its range of tunable lasers for spectroscopy and optical coherence tomography (OCT). The HSL-1 is based on advanced electrically pumped VCSEL (Vertical Cavity Surface Emitting Laser) technology. An attractive laser for SS-OCT applications the HSL-1 takes advantage of a number of features intrinsic to VCSELs to deliver best-in-class performance, including long coherence length, variable scan speed and low signal noise. The HSL-1 has been designed with system integration in mind; a compact, efficient package the laser ...

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      Mentions: Santec
    19. Research Assistant in Photonics/Optical Coherence Tomography at University of Kent

      Research Assistant in Photonics/Optical Coherence Tomography at University of Kent

      Ref STM0549 Location Canterbury Job Type Research Contract Type Fixed Term Salary Type Pro Rata Salary (£) 26274 STM0549, School of Physical Sciences, Closing date: 23 Feb 2015 The Role We are seeking to appoint a Research Associate which is supported by the grant: "Combined time domain and spectral domain coherence gating for imaging and biosensing", funded by the European Research Council (ERC), "Ideas" Specific programme, Advanced, the 7th framework, for 8 months. http://www.kent.ac.uk/physical-sciences/research/aog/European_Research_Council_Grant.html The research activity of the RA as part of the ERC grant will tackle extensions and applications of ...

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    20. Sensors Unlimited Introduces Fastest SWIR 2048-Pixel Line Scan Camera to Support Medical Diagnosis

      Sensors Unlimited Introduces Fastest SWIR 2048-Pixel Line Scan Camera to Support Medical Diagnosis

      Sensors Unlimited, a UTC Aerospace Systems business, has introduced its fastest 2k pixel shortwave infrared (SWIR) line scan camera. The GL2048R camera is specially-designed for applications in spectral-domain optical coherence tomography (SD-OCT), making it an ideal component for imaging the retina and choroid, the blood vessel below the retina. UTC Aerospace Systems is a unit of United Technologies Corp. (NYSE:UTX). The higher speed of this new SWIR camera allows the entire front of the eye – from the top of the cornea through to the bottom of the lens – to be imaged in literally the blink of an eye. Thus ...

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    21. Andy Hill Appointed Chief Executive Officer of Michelson Diagnostics

      Andy Hill Appointed Chief Executive Officer of Michelson Diagnostics

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, announces the appointment of Andy Hill as Chief Executive Officer, effective from 1 February 2015. Jon Holmes will remain with the Company and take up the newly created role of Chief Technology Officer. Andy, aged 52, has substantial commercial experience in the international medical device industry with a track record of building early stage businesses with new and disruptive technologies in a wide range of clinical settings. Most recently, Andy was CEO and co-founder of Intelligent Ultrasound, a medical imaging software spinout from the ...

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    22. Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration)

      Feature Of The Week 02/01/2015: Progress on Developing Adaptive Optics OCT for In Vivo Retinal Imaging: Monitoring and Correction of Eye Motion Artifacts (with Audio Narration)

      Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking ...

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    23. Compact Imaging Granted Three New Patents for Miniature OCT Technology

      Compact Imaging Granted Three New Patents for Miniature OCT Technology

      Compact Imaging, Inc. (CI), an early stage technology company developing proprietary miniature optical sensors for the rapidly growing mobile personal health monitoring and fingerprint authentication markets, today announced that it has been granted three additional patents in the field. CI’s intellectual property base, consisting of 14 US patents and an equal number of pending US and foreign applications, is centered on MRO™, the Company’s proprietary miniature version of optical coherence tomography (OCT). OCT is a well-established, non-invasive, non-ionizing imaging technology widely used in clinical diagnostic applications, according to CEO Don Bogue. “Our miniature OCT architecture, MRO™, can be ...

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    24. Innoluce 2.5 mm Forward Looking OCT Catheter

      Innoluce 2.5 mm Forward Looking OCT Catheter

      A next step in forward looking OCT catheters has been made by Innoluce. A miniaturized MEMS mirror in the tip of the catheter allows for a forward looking OCT scan with a B-scan dimension of ~5mm. The catheter is designed to be used in liquid environment, to be started within the Bladder for cancer diagnostics, but other locations in the body are also possible. First OCT scans of a finger tip with the components showed already a good OCT image quality. Final assembly of the first forward looking OCT catheters is planned for the coming months. At the Photonics West ...

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      Mentions: Innoluce
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