1. Optical Coherence Tomography News

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    1. First Annual OCT Angiography Summit Signals a New Era in Imaging Technology

      First Annual OCT Angiography Summit Signals a New Era in Imaging Technology

      OCT Angiography: The Next Game Changer in OCT Scientists, clinicians and engineers from throughout the world gathered in Portland, Oregon, USA for the first annual OCT Angiography Summit meeting. Participants spent the day sharing their knowledge and discussing applications of a breakthrough imaging technology that may someday transform the way we diagnose and care for patients with the most common causes of blindness, namely macular degeneration, glaucoma and diabetes. Currently, these innovations are being applied in ophthalmology and are proving to be a superior alternative to dye-based methods for visualizing and measuring blood flow in the back of the eye ...

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    2. Swept-Source OCT: Patent License Agreement between Massachusetts General Hospital and Heidelberg Engineering

      Swept-Source OCT: Patent License Agreement between Massachusetts General Hospital and Heidelberg Engineering

      Heidelberg Engineering has entered into a patent license agreement with Massachusetts General Hospital (MGH) in Boston. The agreement grants global and exclusive rights to 77 basic patents and patent applications which relate to swept-source OCT technology and its application in ophthalmology. Spectral domain OCT has become indispensable to eye care professionals worldwide to diagnose and follow-up patients with diseases of the posterior segment of the eye, such as age-related macular degeneration, diabetic retinopathy, or glaucoma. Swept-source OCT technology has specific characteristics which are ideal to acquire comprehensive information about a wide variety of properties of the anterior part of the ...

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    3. Wasatch Photonics Receives a NIH Grant for a Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives a NIH Grant for a Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives a NIH Grant for $27,960 for a Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications. The principal investigator is Roman Kuranov. The program began in 2015 and ends in 2015. Below is a summary of the proposed work. During this SBIR Phase I project we propose to build and test in phantoms a prototype of an innovative cost-effective Optical Coherence Tomography (OCT) system with a 10X increase in acquisition rate compared to commercially available systems. Further development may add an additional 10X increased acquisition rate for a total of 100X. Current market demand for Mega ...

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    4. MGH Receives NIH Grant for Developing Algorithms for MR and OCT-Based Architectonic and Laminar Segmentatio

      MGH Receives NIH Grant for Developing Algorithms for MR and OCT-Based Architectonic and Laminar Segmentatio

      Massachusetts General Hospital Receives a 2015 NIH Grant for $587,704 for developing Algorithms for MR and OCT-Based Architectonic and Laminar Segmentation. The principal investigator is Bruce Fischl. The program began in 2015 and ends in 2019. Below is a summary of the proposed work. The human brain is made up of an array of functionally and structurally defined regions. Localizing these regions is critical for early diagnosis of an array of diseases such as Alzheimer's disease (AD), as well as for neuroscientific research aimed at understanding the brain's functional and structural properties and clinical intervention in drug-resistant ...

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    5. Northwestern University Has an Opening For Software Engineer

      Northwestern University Has an Opening For Software Engineer

      Functional Optical Imaging lab (FOIL) in the Department of Biomedical Engineering at Northwestern University develops optical imaging and sensing technologies for biomedical applications, including ophthalmology, vision science, neuroscience, HIV, and cancers. We are looking for a computer guru who speaks perfect LabView and C++ to work on a clinical retinal imaging instrumentation project. The successful candidate is expected to work on both Evanston and Chicago campuses. For more information, please visit the FOIL website http://foil.northwestern.edu or contact Prof. Hao F. Zhang (hfzhang @ northwestern.edu ).

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    6. OCT Medical Imaging Inc. Receives fast-track SBIR funding for “Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system

      OCT Medical Imaging Inc. Receives fast-track SBIR funding for “Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system

      Dr. Ram Ramalingam CEO of OCT Medical Imaging Inc., (OCTMI), a privately held medical device company announced that it has received a fast-tract Small Business Innovation Research (SBIR) grant from SBIR funding as National Heart Lung Blood institute (NHLBI) for “Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system”. This fast-track SBIR grant worth 2.9 million dollar with potential support for two and half-year will be led by Dr. Ram Ramalingam, Co-founder of OCTMI and will involve clinicians from Columbia University Medical School (CUMS) and University of California Irvine Medical School (UCIMS), Orange, California. This milestone based ...

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    7. Stanford University Receives NIH Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives NIH Grant for Molecular Imaging of Protein Glycosylation in Living Subjects

      Stanford University Receives a 2015 NIH Grant for $392,576 for Molecular Imaging of Protein Glycosylation in Living Subjects. The principal investigator is Adam De La Zerda. The program began in 2012 and ends in 2017 The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic in time, space and environment. Hence, in order to ...

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    8. Post Doctoral Opening In Novel Optical Microscopy Technologies for Neuroscience Applications at Northwestern University

      Post Doctoral Opening In Novel Optical Microscopy Technologies for Neuroscience Applications at Northwestern University

      We have an immediate opening at Northwestern University (Evanston, IL) for one post-doctoral position to develop novel optical microscopy technologies for neuroscience applications. We especially encourage applicants with extensive instrumentation experiences in optics, two-photon, super-resolution or light-sheet microscopy. The successful candidate will be based in the Department of Neurobiology (Kozorovitskiy lab), also working closely with the laboratories of Hao F. Zhang (Department of Biomedical Engineering) and Gregory Schwartz (Department of Ophthalmology). Please submit CV, a cover letter and names and contact information of three references to Y. Kozorovitskiy and H. F. Zhang ( yevgenia.kozorovitskiy@northwestern.edu , hfzhang@northwestern.edu ).

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    9. Oregon Health and Science University Receives NIH Grant for Studying In Vivo Organ of Corti Mechanoelectric Physiology

      Oregon Health and Science University Receives  NIH Grant for Studying In Vivo Organ of Corti Mechanoelectric Physiology

      Oregon Health and Science University Receives a 2015 NIH Grant for $370,365 for Studying In Vivo Organ of Corti Mechanoelectric Physiology. The principal investigator is Alfred Nuttall. THe program began in 1979 and ends in 2016. Below is a summary of the proposed work. A goal of the cochlear physiology laboratory is to understand how the components of the organ of Corti enhance the sound induced vibration of the basilar membrane, a process known as cochlear amplification (CA). Two questions of broad interest are to be studied; how do the outer hair cells transmit force to activate the CA ...

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    10. Johns Hopkins University Receives NIH Grant for a OCT-Guided Free-Hand Semi-Automated Microsurgical Tool for Enhanced Retinal Surgery

      Johns Hopkins University Receives NIH Grant for a OCT-Guided Free-Hand Semi-Automated Microsurgical Tool for Enhanced Retinal Surgery

      Johns Hopkins University Receives a 2015 NIH Grant for $445,134 for a OCT-Guided Free-Hand Semi-Automated Microsurgical Tool for Enhanced Retinal Surgery. The principal investigator is Jin U. Kang. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Contemporary retinal microsurgery is performed by skilled surgeons through operating microscopes, utilizing free hand techniques and manually operated precision micro-instruments. We have assembled an interdisciplinary team including a clinician scientist and vitreoretinal surgeon, an optical device scientist and a systems integrator to translate existing and developing technology in our laboratories into practical application. To ...

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    11. Columbia University Receives NIH Grant for Measures of Human Receptor and Post Receptor Activity

      Columbia University Receives NIH Grant  for Measures of Human Receptor and Post Receptor Activity

      Columbia University Receives a 2015 NIH Grant for $581,231 for Measures of Human Receptor and Post Receptor Activity. The principal investigator is Donald Hood. The program began in 1991 and ends in 2016. Below is a summary of the proposed work. Our long-term objective has been to develop a set of noninvasive techniques for studying the human retina. By applying novel techniques and current theories of phototransduction to the full-field electroretinogram (ERG), we have successfully developed widely-used noninvasive techniques for studying the global activity of the rod and cone receptors, as well as the rod bipolar cells. These indices ...

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    12. Cleveland Clinic Receives NIH Grant to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives NIH Grant to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic Receives a 2015 NIH Grant for $203,124 to Study Intraoperative Optical Coherence Tomography for Ophthalmic Surgery. The principal investigatgor is Justis Ehlers. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Optical coherence tomography (OCT) has revolutionized the management of ophthalmic diseases with the precise anatomic information it provides with non-invasive imaging. The high-resolution cross-sectional tissue details make OCT a natural complement to ophthalmic surgery. Intraoperative OCT (iOCT) has the potential to provide real-time feedback to surgeons thus improving surgical care and outcomes. This research activity will focus on ...

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    13. Postdoctoral Researcher in Photonics Technologies for Miniature Biometric and Healthcare Instrumentation at the National University of Ireland, Galway

      Postdoctoral Researcher in Photonics Technologies for Miniature Biometric and Healthcare Instrumentation at the National University of Ireland, Galway

      Postdoctoral Researcher in Photonics technologies for miniature biometric and healthcare instrumentation ‘Multiple-Reference Optical Coherence Tomography’ (MR-OCT) Tissue Optics and Microcirculation imaging Laboratory School of Physics National University of Ireland, Galway Ref. No. NUIG 095-15 Applications are invited from suitably qualified candidates for a full-time, fixed term position as a photonics technology postdoctoral research scientist with the Tissue Optics and Microcirculation Imaging Facility Laboratory (TOMI) at the National University of Ireland, Galway. This position is funded by a mix of commercial and public funding. The position is available from the 1st of September 2015 on a two year fixed term contract ...

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    14. Post-doctoral Research Fellowship at Yale in Cardiovascular Molecular and Translational Imaging

      Post-doctoral Research Fellowship at Yale in Cardiovascular Molecular and Translational Imaging

      Post-doctoral research fellowship immediately available at Yale on NIH funded T32 training grant focused on providing multi-disciplinary multi-modality training in molecular and translational cardiovascular imaging for highly qualified fellows holding either a MD or/and PhD, in preparation for academic careers as independent investigators in the highly clinically relevant field of cardiovascular imaging. Post-doctoral fellowship training will be 2-3 years in duration. There are three primary research focuses in the post-doctoral training, 1) cardiovascular molecular imaging, 2) cardiovascular imaging technologies and analyses, and 3) translational cardiovascular imaging. Applicants will have full access to resources available through the Yale Translational Research ...

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    15. Rowe Technical Design, Inc. announces that Whole Model Eye for OCT (Tissue Phantom) is now in production!

      Rowe Technical Design, Inc. announces that Whole Model Eye for OCT (Tissue Phantom) is now in production!

      Rowe Technical Design, Inc. (RTD), developers of the 1st commercial optical tissue phantom for OCT, announces that their latest version of the Whole Model Eye complete with Cornea, Crystalline Lens and Retina tissue phantoms for OCT has now been released for full serial production. “We’re excited because this is our third serial production model eye, following up on the very successful anterior chamber and OCT model eyes with retina tissue phantom” notes T. Scott Rowe, company founder and president. “We are extremely pleased with the customer feedback so far, and we are ready for serial production. This is the ...

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      Mentions: T. Scott Rowe
    16. University of Alabama at Birmingham Receives NIH Grant to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT.

      University of Alabama at Birmingham Receives NIH Grant to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT.

      The University of Alabama at Birmingham Receives a 2015 NIH Grant for $498,330 to Study Functional Anatomic Imaging of Cystic Fibrosis Patients with Early Lung Disease using Micro-OCT. The principal investigator is Steven Mark Rowe. The program began in 2012 and elndsi nin 2016. Below is a summary of the proposed work. Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), an anion transporter of chloride and bicarbonate. Defective or deficient CFTR leads to severe mucoobstructive lung disease and severe morbidity and early mortality due to lung infections. Even though substantial advances in ...

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    17. Perimeter Medical Imaging Closes Oversubscribed $5 Million Series A Financing Round Led By Roadmap Capital

      Perimeter Medical Imaging Closes Oversubscribed $5 Million Series A Financing Round Led By Roadmap Capital

      Perimeter Medical Imaging, Inc., a developer of real time imaging systems for in-surgery tissue assessment, is pleased to announce the closing of their $5 million Series A financing. The round was led by Roadmap Capital with participation from EPIC Capital, NorthView Ventures and Pathfinder Asset Management. Funds will support the completion of their current clinical study at Princess Margaret Cancer Centre as well as product development and FDA regulatory clearance for their first tissue imaging product. Perimeter’s ground-breaking new Optical Tissue Imaging System (OTIS™) is an intraoperative medical imaging tool that provides clinicians with the ability to visualize the ...

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    18. FedDev Ontario Supports Commercialization of Perimeter Medical Imaging’s OTIS™ Surgical Tissue Imaging System

      FedDev Ontario Supports Commercialization of Perimeter Medical Imaging’s OTIS™ Surgical Tissue Imaging System

      Perimeter Medical Imaging, Inc., a developer of real time imaging systems for in-surgery tumour margin assessment, today announced it is receiving up to $980,000 from the Government of Canada through the Federal Economic Development Agency for Southern Ontario (FedDev Ontario). The announcement was made at Perimeter’s new location in Toronto by John Carmichael, Member of Parliament for Don Valley West, on behalf of the Honourable Gary Goodyear, Minister of State for the Federal Economic Development Agency for Southern Ontario (FedDev Ontario). This investment will support the next phase of product and clinical development as well as accelerate regulatory ...

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    19. Case Western Reserve University Receives NIH Grant for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging

      Case Western Reserve University Receives NIH Grant for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging

      Case Western Reserve University Receives a 2015 NIH grant for $198,125 for Cardiac Radiofrequency Ablation Catheter with Integrated OCT Imaging. The principal investigator is Andrew Rollins. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. The long-term goal of this research program is to develop catheter-based optical coherence tomography (OCT) imaging tools that will improve the care of patients suffering from cardiac arrhythmias. This project aims to improve radiofrequency ablation (RFA) therapy, which is the standard of care for many arrhythmias, by providing microscopic image guidance at the tip of the ...

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    20. Johns Hopkins University Receives NIH Grant for Studying OCT to Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer.

      Johns Hopkins University Receives NIH Grant for Studying OCT to Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer.

      Johns Hopkins University Receives a 2015 NIH Grant for $48,120 for OCT to Distinguish B/T Tumor &Non-Tumor Tissue in Infiltrating Brain Cancer. The principal investigator is Carmen Kut. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. In brain cancers such as gliomas, aggressive removal of the solid tumor through surgery is associated with improved overall survival. In fact, i has been shown that at least 78% of the tumor has to be removed to make a meaningful difference in the patient's survival. Current techniques for tumor removal are ...

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    21. Serving unmet needs with OCT Webcast with Dr. Mark Brezinski

      Serving unmet needs with OCT Webcast with Dr. Mark Brezinski

      To view this webcast click HERE . This webcast was originally broadcast on July 16, 2015 and is now available for on demand viewing. What Steve Jobs referred to as “the unmet need” is a barrier to effective treatment, scientific discovery—and equipment sales. Traditionally, developers (engineers) strive for precision, elegance, and maximum theoretical performance (e.g. resolution), whereas the end user (physician or researcher) often has very different requirements. Unfortunately, efforts to bridge this gap can easily become confused. In this webcast, biophotonics pioneer Mark Brezinski MD explores unmet needs in biomedicine, using examples in OCT to illustrate how developers ...

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    22. Massachusetts General Hospital Receives NIH grant for the center for Biomedical OCT Research and Translation.

      Massachusetts General Hospital Receives  NIH grant for the center for Biomedical OCT Research and Translation.

      Massachusetts General Hospital Receives a 2015 NIH grant for $1,086,563 for the Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) has evolved into a powerful microscopy technique for a broad range of applications in biology and clinical medicine. It can safely be used to image biological tissue with high resolution and can easily integrate flexible, narrow diameter optical fiber probes for imaging internal organs. Recent advances have increased OCT imaging speeds by ...

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    23. Stanford University Receives NIH Grant for Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives NIH Grant for Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives a 2015 NIH Grant For $392,576 for Molecular Imaging of Protein Glycoslation in Living Subjects. The principal investigator is Adam De La Zerda. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic in ...

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    24. Stanford University Receives NIH Grant to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives  NIH Grant  to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a 2015 NIH Grant for $461,667 to Study Enhalnced Clinical Diagnosis of Early Osteoarthritis. The principal investigator is Constance Chu. The program began in 2005 and ends in 2016. Below is a summary of the proposed work. Osteoarthritis is a leading cause of disability, and a major public health issue. Progressive loss of articular cartilage due to injury and degeneration are important etiological factors in the development of osteoarthritis. While laboratory studies show a potential to reverse pathological changes in articular cartilage prior to breakdown of the articular surface, a major barrier to clinical translation of ...

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