1. Optical Coherence Tomography News

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    1. Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University

      Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University

      The Center for Ophthalmic Optics and Lasers www.COOLLab.net , Casey Eye Institute, Oregon Health & Science University, is seeking outstanding candidates for the following position in optical imaging research in the field of ophthalmology. Post-Doc (software): optical signal processing, image processing Requirements: PhD degree in a relevant discipline (Biomedical Engineering, Medical Physics, computer science, applied mathematics) is required. Solid background in optical signal processing, (medical) image analysis, segmentation and/or image registration are essential. Experiences in imaging (scanning laser ophthalmoscopy, angiography, microscopy, oximetry, adaptive optics), and software development (GPU programming) are also desirable. The successful candidate will be supervised by ...

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    2. This is Your Brain's Blood Vessels on Cocaine

      This is Your Brain's Blood Vessels on Cocaine

      New imaging technique shows how cocaine shuts down blood flow in mouse brains A new method for measuring and imaging how quickly blood flows in the brain could help doctors and researchers better understand how drug abuse affects the brain, which may aid in improving brain-cancer surgery and tissue engineering, and lead to better treatment options for recovering drug addicts. The new method, developed by a team of researchers from Stony Brook University in New York, USA and the U.S. National Institutes of Health, was published today in The Optical Society’s ( OSA ) open-access journal Biomedical Optics Express . The ...

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    3. University of Arizona Receives NIH Grant for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention

      University of Arizona Receives NIH Grant for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention

      University of Arizona Receives a 2014 NIH Grant for $294,662 for Translational Studies and Clinical Pharmacology of New Drugs for Chemoprevention. The principal investigator is Steven Stratton The program began in 2014 and ends in 2015 Below is a summary of the proposed work. Project 3 will test and clinically validate mechanisms and pharmacologic strategies explored in Projects 1-2, which target Akt-mTOR, AMPK-mTOR, and Fyn/RSK pathways. Advanced clinical/translational study of skin cancer carcinogenesis, biology, and pathophysiology will help reduce morbidity/ mortality, provide insight into keratinocyte signaling, and provide an easily-accessed human model of full-spectrum carcinogenesis for other ...

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    4. Columbia University Receives NIH Grant for Measures Of Human Receptor and Post Receptor Activity

      Columbia University Receives NIH Grant for Measures Of Human Receptor and Post Receptor Activity

      Columbia University Receives 2014 NIH Grant for $532,143 for Measures Of Human Receptor and Post Receptor Activity. The principal investigator is Donald Hood. The program began in 1991 and ends in 2016. Below is a summary of the proposed work. Our long-term objective has been to develop a set of noninvasive techniques for studying the human retina. By applying novel techniques and current theories of phototransduction to the full-field electroretinogram (ERG), we have successfully developed widely-used noninvasive techniques for studying the global activity of the rod and cone receptors, as well as the rod bipolar cells. These indices of ...

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    5. University of Washington Received a 2014 NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas

      University of Washington Received a 2014 NIH Grant for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas

      University of Washington Received a 2014 NIH Grant For $232,550 for Needle Biopsy Preservation and Preparation for Rapid 3D Pathology of Pancreas. The principal investigator is Eric Seibel. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. There are over three million needle biopsies performed every year in the USA, typically for the diagnosis of breast, prostate, thyroid, lung, liver, and pancreatic cancers. Because needle biopsies are less invasive than surgical biopsies, they are much more cost-effective. However, a major limitation for all needle biopsies are that the pathologist or cytologist ...

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    6. UC Irvine Receives NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      UC Irvine Receives NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Received a 2014 NIH Grant for $598,705 for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging. The principal investigator is Zhongping Chen. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography (OCT), ultrasound (US), and phase-resolved acoustic radiation force optical coherence elastography (ARF-OCE). The multimodal intravascular imaging system is unique in that it combines the advantages of the high spatial resolution ...

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    7. Postdoctoral Research Associate at University of Liverpool

      Postdoctoral Research Associate at University of Liverpool

      £31,644 - £36,661 pa Faculty of Science and Engineering, Institute of Electrical Engineering and Electronics, Department of Electrical Engineering and Electronics Location: University Campus Ref: R-585803/WWW Closing date for receipt of applications: Fri, 22 Aug 2014 17:00:00 BST To undertake a project “ I ntelligent Manufacturing of Pharmaceutical Film Coating Using Terahertz Pulsed Imaging, Optical Coherence Tomography and Numerical Modelling ” in collaboration with Cambridge University. You will primarily focus on the development and integration of an optical coherence tomography (OCT) sensor for online monitoring and quality control of pharmaceutical coating process. The duties include OCT sensor instrumentation ...

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    8. Postdoctoral Opening at Biophotonics Laboratory at Yale University

      Postdoctoral Opening at Biophotonics Laboratory at Yale University

      There is an immediate opening at Yale University for a postdoctoral associate to work on a newly-funded research project entitled “Massively parallel interferometric confocal microscopy using degenerate lasers.” The postdoctoral associate will be supervised by Michael A. Choma, MD, PhD (Yale Diagnostic Radiology) in collaboration with Hui Cao, PhD (Yale Applied Physics). The postdoctoral associate will work in a highly collaborative and interdisciplinary environment to develop next-generation laser technologies to enable new kinds of biomedical optical imaging systems. We are particularly interested in candidates who have experience in designing and building solid-state lasers, but candidates with excellent skills in designing ...

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    9. Johns Hopkins University Receives NIH Grant to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer

      Johns Hopkins University Receives  NIH Grant to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer

      Johns Hopkins University Receives a 2014 NIH Grant for $47,676 to investigate OCT To Distinguish B/T Tumor & Non-Tumor Tissue in Infiltrating Brain Cancer. The principal investigator is Carmen Kut. The program began in 2014 and ends in 2017. Below is a summary of the proposed work. In brain cancers such as gliomas, aggressive removal of the solid tumor through surgery is associated with improved overall survival. In fact, i has been shown that at least 78% of the tumor has to be removed to make a meaningful difference in the patient's survival. Current techniques for tumor removal ...

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    10. Stanford University Receives a NIH grant for Enhanced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a NIH grant  for Enhanced Clinical Diagnosis of Early Osteoarthritis

      Stanford University Receives a 2014 NIH grant for $460,742 for Enhanced Clinical Diagnosis of Early Osteoarthritis. The principal investigator was Constance Chu. The program began in 2005 and ends in 2016. Below is a summary of the proposed work. Osteoarthritis is a leading cause of disability, and a major public health issue. Progressive loss of articular cartilage due to injury and degeneration are important etiological factors in the development of osteoarthritis. While laboratory studies show a potential to reverse pathological changes in articular cartilage prior to breakdown of the articular surface, a major barrier to clinical translation of these ...

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    11. Research Fellow (or Research assistant) Massachusetts General Hospital / Harvard Medical School , Cambridge, MA

      Research Fellow (or Research assistant) Massachusetts General Hospital / Harvard Medical School , Cambridge, MA

      Research Fellow (or Research assistant) Massachusetts General Hospital / Harvard Medical School , Cambridge, MA, United States Employer Description The Wellman Center for Photomedicine Job Description Yun Lab at Harvard Medical School and the Wellman Center for Photomedicine at MGH has one open position for postdoctoral fellow with PhD in the field of optical coherence tomography. More information, visit http://www2.massgeneral.org/wellman/faculty-yun-pi.htm or http:// www.intelon.org (Applications for technical assistantship will also be received.) To apply, send a full CV and a cover letter to Prof. Yun at syun@hms.harvard.edu. Job Requirements Solid understanding of ...

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    12. Senior Scientist Position Open at Carl Zeiss Meditec in Dublin California

      Senior Scientist Position Open at Carl Zeiss Meditec in Dublin California

      The Senior Scientist is responsible for the initiation, design, development, and implementation of scientific research projects to explore technology for future platform concepts and support the development and execution of product roadmaps. Will investigate the feasibility of applying scientific principles and concepts to potential inventions and products. Maintains substantial knowledge of state-of the-art principles and theories and may contribute to scientific literature and conferences. May participate in development of intellectual property and visit clinical sites and interact with the market to provide inputs to the R&D teams about various possible system design improvements. May identify and work with external ...

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    13. University of Pittsburgh Receives a 2014 NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      University of Pittsburgh Receives a 2014 NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      University of Pittsburgh Receives a 2014 NIH Grant for $726,299 for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. The program began in 2000 and ends in 2019. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness and visual morbidity. Because the disease causes irreversible damage to neural tissue it is of utmost importance to identify glaucoma and its progression at the earliest possible stages. Through advancements in the use of optical coherence tomography (OCT) and other technologies, the long-term goal of this research project is to precisely ...

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    14. Johns Hopkins University Receives a 2014 NIH Grant for 3D Segmentation and Registration of Macular SD-OCT for Applications in Multiple Sclerosis

      Johns Hopkins University Receives a 2014 NIH Grant for 3D Segmentation and Registration of Macular SD-OCT for Applications in Multiple Sclerosis

      Johns Hopkins University Receives a 2014 NIH Grant for $387,284 for 3D Segmentation and Registration of Macular SD-OCT for Applications in Multiple Sclerosis. The principal investigator is Jerry Prince. Below is a summary of the proposed work. Vision is compromised in at least 55% of multiple sclerosis (MS) patients and may represent the very first manifestation of disease onset. Spectral domain optical coherence tomography (SD-OCT) enables in-vivo, high-resolution studies of the retina, and is increasingly being used as a biomarker in neurodegenerative diseases. SD-OCT has provided phenotypical measurements of the retinal nerve fiber layer, ganglion cell layer, and overall ...

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    15. MGH Receives NIH Grant for Microscopic Imaging of Neuro-Capillary Coupling in Brain Cortex.

      MGH Receives  NIH Grant for Microscopic Imaging of Neuro-Capillary Coupling in Brain Cortex.

      Massachusetts General Hospital Receives a 2014 NIH Grant for $90,000 for Microscopic Imaging of Neuro-Capillary Coupling in Brain Cortex. The principal investigator is Jonghwan Lee. A summary of the proposed work is given below. Optical coherence tomography (OCT) enables um-resolution and high-speed imaging of tissue structure, facilitating a number of basic and clinical studies in ophthalmology, cancer biology, and neuroscience. Through the proposed K99/R00 program, the candidate will develop novel OCT-based technologies for um-resolution imaging of tissue dynamics, especially in the brain cortex of a living animal. In detail, the candidate will develop three technologies for imaging various ...

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    16. Wasatch Photonics Receives an NIH SBIR Grant for Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives an NIH SBIR Grant for Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications

      Wasatch Photonics Receives an NIH SBIR Grant for $207,045 for Cost-Effective MHz Rate Optical Coherence Tomography for Biomedical Applications. The principal investigator is Roman Kuranov. The program began in 2014 and ends in 2015. Below is a summary of the proposed work. During this SBIR Phase I project we propose to build and test in phantoms a prototype of an innovative cost-effective Optical Coherence Tomography (OCT) system with a 10X increase in acquisition rate compared to commercially available systems. Further development may add an additional 10X increased acquisition rate for a total of 100X. Current market demand for Mega ...

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    17. UCSF received a NIH Grant for Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT

      UCSF received a NIH Grant for Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT

      University of California at San Francisco received a 2014 NIH Grant for $333,825 for Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT. The principal investigator is Daniel Fried. The program began in 2006 and ends in 2015. Below is a summary of the proposed work. The overall objective of this proposed research is to develop polarization sensitive optical coherence tomography (PS-OCT) as a non-invasive optical device for the accurate and early clinical assessment of tooth demineralization and remineralization. The central hypothesis underlying this proposal is that the depth-resolved changes in the magnitude of light scattering of dental hard tissues ...

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    18. Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic / CWRU NIH Grant for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery

      Cleveland Clinic/ Case Western Reserve University Receiver 2014 NIH Grant for $203,124 for Intraoperative Optical Coherence Tomography for Ophthalmic Surgery. The principal investigator is Justis Ehlers. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Optical coherence tomography (OCT) has revolutionized the management of ophthalmic diseases with the precise anatomic information it provides with non-invasive imaging. The high-resolution cross-sectional tissue details make OCT a natural complement to ophthalmic surgery. Intraoperative OCT (iOCT) has the potential to provide real-time feedback to surgeons thus improving surgical care and outcomes. This research activity will ...

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    19. Yale University Receives NIH Grant for Massively Parallel Interferometric Confocal Microscopy using Degenerate Lasers

      Yale University Receives  NIH Grant  for Massively Parallel Interferometric Confocal Microscopy using Degenerate Lasers

      Yale University Receives 2014 NIH Grant for $209,850 for Massively Parallel Interferometric Confocal Microscopy using Degenerate Lasers. The principal nvestigator is Michael Choma. Below is a summary of the proposed work. Confocal microscopy uses geometric principles to generate cross-sectional images of scattering biological tissue. Traditional reflectance confocal microscopes use serial pixel acquisition, thereby limiting acquisition speeds. Parallelization of pixel acquisition would dramatically increase imaging speeds and enable the study of new kinds of physiology. For example, massively parallelized reflectance confocal microscopy would be invaluable in the emerging field of cilia-driven mucus physiology in the respiratory system. Indeed, in terms ...

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    20. Volcano Corporation to Divest Axsun and Settle All Ongoing Litigation with St. Jude

      Volcano Corporation to Divest Axsun and Settle All Ongoing Litigation with St. Jude

      In the recent Volcano Corporation Security and Exchange Commission Form 10-Q it appears St. Jude and Volcano have made progress at settling most or all of their on going litigation related OCT. Below is an excerpt from page 19 of Form 10-Q . "On August 7, 2014, Volcano Corporation (“Volcano”) and its wholly-owned subsidiary, Axsun Technologies, Inc. (“Axsun” and together with Volcano, the “Volcano Parties”), entered into a Settlement, Release, License Agreement, and Covenants Not To Sue (the “Agreement”) with St. Jude Medical, Inc. (“St. Jude”) and its affiliates St. Jude Medical, Cardiology Division, Inc., St. Jude Medical Systems AB, St ...

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    21. Two research scientist positions are available in the Vision Science and Advanced Retinal Imaging Laboratory at the University of California, Davis

      Two research scientist positions are available in the Vision Science and Advanced Retinal Imaging Laboratory at the University of California, Davis

      Two research scientist positions are available in the Vision Science and Advanced Retinal Imaging Laboratory at the University of California, Davis. One position will be filled by someone with background in vision science while the other will be for a person with experience in a high-resolution imaging modality such as OCT, adaptive optics or scanning laser ophthalmoscope. Strong skills in programming or image processing would be an asset. The positions will be open until filled. Salary will be based on experience and salary scales of the UC. The University of California is committed to diversity. Minorities, women, veterans and persons ...

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    22. Bioptigen Receives New US Patent for Intrasurgical OCT System

      Bioptigen Receives New US Patent for Intrasurgical OCT System

      Foundational patent for intrasurgical OCT marks the company's focus on emerging market for ophthalmic surgical imaging MORRISVILLE, NC August 5, 2014 Bioptigen Inc. announces today that it has received a new US Patent presenting innovative concepts integrating Optical Coherence Tomography (OCT) Systems to Surgical Microscopes. The patent, US 8,777,412 Surgical Microscopes Using Optical Coherence Tomography and Related Methods, by Buckland E.L., et. al. includes claims for independent OCT focus and zoom control for optimizing images from the cornea to the retina, and puts forward key elements of Bioptigen's approach for incorporating OCT into new and ...

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    23. Massachusetts General Hospital Receives NIH Grant for The Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives NIH Grant for The Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives 2014 NIH Grant For $1,449,151 for The Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) has evolved into a powerful microscopy technique for a broad range of applications in biology and clinical medicine. It can safely be used to image biological tissue with high resolution and can easily integrate flexible, narrow diameter optical fiber probes for imaging internal organs. Recent advances have increased OCT imaging speeds by nearly ...

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    24. Postdoctoral Research Associate Opening at University of Liverpool

      Postdoctoral Research Associate Opening at University of Liverpool

      Postdoctoral Research Associate £31,644 - £36,661 pa Faculty of Science and Engineering, Institute of Electrical Engineering and Electronics, Department of Electrical Engineering and Electronics Location: University Campus Ref: R-585803/WWW Closing date for receipt of applications: Fri, 22 Aug 2014 17:00:00 BST To undertake a project “ I ntelligent Manufacturing of Pharmaceutical Film Coating Using Terahertz Pulsed Imaging, Optical Coherence Tomography and Numerical Modelling ” in collaboration with Cambridge University. You will primarily focus on the development and integration of an optical coherence tomography (OCT) sensor for online monitoring and quality control of pharmaceutical coating process. The duties include ...

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