1. Optical Coherence Tomography News

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    1. Massachusetts General Hospital Receives NIH Grant for Less Invasive Assessment of Inflammation and Subepithelial Remodeling in Eosinophlic Esophagitis Patients

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      Massachusetts General Hospital Receives NIH Grant for Less Invasive Assessment of Inflammation and Subepithelial Remodeling in Eosinophlic Esophagitis Patients

      Massachusetts General Hospital Receives a 2020 NIH Grant for $683,034 for Less Invasive Assessment of Inflammation and Subepithelial Remodeling in Eosinophlic Esophagitis Patients. The principal investigator is Guillermo Tearney. Below is a summary of the proposed work. Eosinophilic esophagitis (EoE) is a prevalent allergic response to food that causes eosinophilic infiltration in the esophagus. EoE can lead to esophageal remodeling, scarring, muscle hypertrophy, and stricture, decreasing quality of life and increasing risk of food impaction. Diagnosis of EoE is made by finding epithelial esophageal eosinophilia in biopsies acquired during upper endoscopy. Patients are treated with topical corticosteroids or dietary ...

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      Mentions: Guillermo J. Tearney National Institutes of Health Massachusetts General Hospital

    2. Northwestern University Receives NIH Grant for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography

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      Northwestern University Receives NIH Grant for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography

      Northwestern University Receives a 2020 NIH Grant for $50,520 for Oxygen Delivery and Metabolism in Diabetic Retinopathy Using Visible-Light Optical Coherence Tomography. The principal investigator is Biran Soetikno. Below is a summary of the proposed work. The retina is one of the most metabolically active tissues in the human body, making it particularly susceptible to hypoxia. In diabetic retinopathy (DR), aberrant oxygen metabolism has been hypothesized to play a pivotal role its pathogenesis. An improved understanding of how imbalances in oxygen delivery and demand lead to the progression of DR is a great but worthwhile challenge, especially considering the ...

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      Mentions: National Institutes of Health Northwestern University

    3. Stanford University Receives NIH Grant for Imaging Structure and Function

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      Stanford University Receives NIH Grant for Imaging Structure and Function

      Stanford University Receives a 2020 NIH Grant for $139,730 for Imaging Structure and Function. The principal investigator is Thomas Clandinin. Below is a summary of the proposed work. Imaging technologies such as confocal microscopy, multiphoton microscopy and super- resolution imaging as well as optical coherence tomography have transformed the ability of scientists to observe structural and functional changes in the visual system, in vivo and ex vivo, in both health and disease. The overarching goal of the imaging core is to transform the ability of vision scientists to use these critical technologies by providing access to and training on ...

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      Mentions: National Institutes of Health Stanford University

    4. Postdoctoral opening in optical instrumentation and retinal imaging at University of Illinois at Chicago

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      Postdoctoral opening in optical instrumentation and retinal imaging at University of Illinois at Chicago

      A postdoctoral position is available in the Biomedical Optics and Functional Imaging Laboratory , Department of Bioengineering , University of Illinois at Chicago (UIC). The Biomedical Optics and Functional Imaging Laboratory is affiliated with the Lions of Illinois Eye Research Institute (LIERI), within the same building with UIC Ophthalmology and Retina Clinic. In collaboration with experienced ophthalmologists and vision scientists, our ongoing research includes ultra-wide field fundus photography, functional optical coherence tomography (OCT), super-resolution ophthalmoscopy, machine learning based image analysis and classification. The postdoctoral fellow will support optical instrument developments, such as fundus camera, OCT and confocal ophthalmoscopy, for retinal imaging of ...

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      Mentions: Xincheng Yao

    5. Baylor College of Medicine Receives a 2020 NIH Grant for Biomechanics of Early Mammalian Cardiogenesis

      Explore Optical Coherence Tomography News Developmental Biology , Funding
      Baylor College of Medicine Receives a 2020 NIH Grant for Biomechanics of Early Mammalian Cardiogenesis

      Baylor College of Medicine Receives a 2020 NIH Grant for $554,542 for Biomechanics of Early Mammalian Cardiogenesis. The principal investigator is Irina Larina. Below is a summary of the proposed work. Human congenital heart defects (CHD) are very common, occurring in nearly 1% of live births. Moreover, cardiovascular (CV) failures are the leading cause of birth defect- related deaths in infants. It is well established that biomechanical stimuli are important regulators of CV development. Thus, defining how mechanical factors are integrated with genetic pathways to coordinate mammalian heart tube function and morphogenesis is critically important for understanding CHD and ...

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      Mentions: National Institutes of Health Baylor College of Medicine Irina V. Larina

    6. University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality

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      University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality

      University of Houston Receives a 2020 NIH Grant for $633,348 for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality. The principal investigator is Kirill Larin. Below is a summary of the proposed work. The objective of this proposal is to develop a non-contact, all-optical imaging technology to map elastic moduli and forces involved in critical aspects of embryonic development with high 3D resolution. The proposed technology is based on combined Brillouin spectroscopy and Optical Coherence Tomography (OCT), which will be used to gain fundamental understanding of biomechanical factors involved during neural tube closure (NTC) in normal and pathological cases ...

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      Mentions: National Institutes of Health Kirill V. Larin University of Houston

    7. Oregon Health and Sciences University Receives a 2020 NIH Grant for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography for Retinopathy of Prematurity

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      Oregon Health and Sciences University Receives a 2020 NIH Grant for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography for Retinopathy of Prematurity

      Oregon Health and Sciences University Receives a 2020 NIH Grant for $341,800 for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography for Retinopathy of Prematurity. The principal investigator is Yifan Jian. Below is a summary of the proposed work. The long-term goal of this project is to determine whether optical coherence tomography (OCT) and OCT angiography (OCTA) might lead more accurate and objective diagnosis, earlier intervention, and improved outcomes in retinopathy of prematurity (ROP). International consensus and National Institute of Health (NIH) funded clinical trials over the last 30 years have defined the phenotypic classifications, natural history, prognosis, and management ...

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      Mentions: National Institutes of Health Oregon Health & Science University Yifan Jian

    8. UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology

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      UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology

      University of California at Irvine Receives a 2020 NIH Grant for $593,557 for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology. The principal investigator is Zhongping Chen. Below is a summary of the proposed work. Each year, 50M Americans suffer from chronic rhinosinusitis (CRS) and allergic rhinitis (AR). The economic impact accounts for over $35B/year in health care expenditures alone, with over 3.5M work and 2M school days lost each year. Accordingly, over 600K operations per year are performed to treat sinonasal disease. The disease burden is immense with a profound ...

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      Mentions: National Institutes of Health Zhongping Chen UC Irvine

    9. UC Irvine Receives a 2020 NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

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      UC Irvine Receives a 2020 NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Receives a 2020 NIH Grant for $698,188 for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging. The principal investigator is Zhongping Chen. Below is a summary of the proposed work. Cardiovascular disease is responsible for 1 in 4 deaths, or 650,000 Americans, every year. It is the leading cause of death in the United States. Ruptured atherosclerotic plaques are the main cause of acute coronary events, and it is of lethal consequence. Clinically, early detection of the latent vulnerability of plaques is the first line of defense against such deadly circumstances, and ...

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      Mentions: National Institutes of Health Zhongping Chen UC Irvine

    10. Lumedica Incorporated Receives a 2020 NIH Grant for Low Cost Retinal Optical Coherence Tomography for Point of Care Use

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      Lumedica Incorporated Receives a 2020 NIH Grant for Low Cost Retinal Optical Coherence Tomography for Point of Care Use

      Lumedica Incorporated Receives a 2020 NIH Grant for $499,919 for Low Cost Retinal Optical Coherence Tomography for Point of Care Use. The principal investigator is William Brown. Below is a summary of the proposed work. The objective of this research is to create a clinical prototype of a new optical coherence tomography (OCT) system suitable for diagnostic retinal imaging at the point of care. The target system price will be one third the price of currently available research OCT systems while providing performance comparable to other entry level OCT imaging systems. By breaking the $15,000 system barrier we ...

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      Mentions: National Institutes of Health William J. Brown Lumedica

    11. Post-doctoral Scholar Position in OCT Endoscopy at the University of North Carolina at Chapel Hill

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      Post-doctoral Scholar Position in OCT Endoscopy at the University of North Carolina at Chapel Hill

      The Coherence Imaging Laboratory at the University of North Carolina at Chapel Hill seeks a highly motivated Postdoc to perform research in optical coherence tomography (OCT) imaging. Research activities will include the development and application of our endoscopic OCT imaging systems for upper airway imaging, and its application for assessment of airway injury and upper airway disorders. Candidates are required to have demonstrated expertise with imaging hardware and hardware design, with particular consideration given to candidates with experience using fiber optics, fabricating fiber optic tips, using and setting up interferometers or similar optical systems, and setting up data acquisition systems ...

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      Mentions: Amy L. Oldenburg University of North Carolina

    12. Perimeter Medical Imaging AI, Inc. Announces Stock Exchange Listing (TSX.V: PINK); Closing of Oversubscribed C$10m Private Placement Financing; Completion of Plan of Arrangement with New World

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      Perimeter Medical Imaging AI, Inc. Announces Stock Exchange Listing (TSX.V: PINK); Closing of Oversubscribed C$10m Private Placement Financing; Completion of Plan of Arrangement with New World

      Medical imaging and AI company Perimeter Medical Imaging AI, Inc. ("Perimeter" or the "Company") announced that the previously announced reverse take-over of New World Resource Corp. (" New World ") by Perimeter Medical Imaging, Inc. (" Pre-Closing Perimeter ") via plan of arrangement (the " Plan of Arrangement ") has been completed. As a result, Perimeter will be listed as a Tier 2 issuer on the TSX-V. Immediately following closing of the Plan of Arrangement, Perimeter, the resulting issuer following the Plan of Arrangement, closed its previously announced non-brokered private placement financing (the " Offering ") of units (" Units ") on an oversubscribed basis for gross proceeds of C ...

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      Mentions: FDA Perimeter Medical Imaging

    13. Medical Imaging and AI for Cancer Surgery - Perimeter Medical Imaging AI Inc Going Public

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      Medical Imaging and AI for Cancer Surgery - Perimeter Medical Imaging AI Inc Going Public

      Medical imaging and AI company Perimeter Medical Imaging AI (PMI) today announces that it will be going public on the TSX Venture Exchange the week of June 29. The Toronto- and Dallas-based company is going public during the same year that it enters the commercial stage for its proprietary, FDA-cleared OCT imaging platform, which is alone in its ability to provide real-time, microscopic-scale imaging information during surgery. PMI’s reserved stock ticker symbol, PINK, is an allusion to the pink ribbons used during Breast Cancer Awareness Month by the Canadian Cancer Society and the American Cancer Society, driving home the ...

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      Mentions: Baylor College of Medicine Harvard University FDA

    14. Case Western Reserve University Receives NIH Grant for Computer Assisted Coronary Artery Stent Interventions

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      Case Western Reserve University Receives NIH Grant for Computer Assisted Coronary Artery Stent Interventions

      Case Western Reserve University Receives a 2020 NIH Grant for $727,994 for Computer Assisted Coronary Artery Stent Interventions The principal investigator is David Wilson. Below is a summary of the proposed work. Computer assisted coronary artery stent interventions Summary When treating highly calcified coronary artery lesions with stents, interventional cardiologists, with limited information, make stressful treatment decisions, which can lead to inadequate stent deployment and poor outcomes, or even rare calamitous events. When calcification is present, a cardiologist must choose to use a normal sized angioplasty balloon; a larger angioplasty balloon with increasingly high, prolonged pressures to fracture the ...

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      Mentions: National Institutes of Health Case Western Reserve University

    15. Wasatch Photonics adds 1600 nm OCT spectrometer for deep tissue imaging

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      Wasatch Photonics adds 1600 nm OCT spectrometer for deep tissue imaging

      Wasatch Photonics has expanded its Cobra OCT spectrometer product line with a new 1600 nm OCT spectrometer for deep-tissue, SD-OCT imaging. The Cobra 1600 builds on the company’s existing line of more than 25 off-the-shelf OCT spectrometer models at visible, 800 nm, 1050 nm, and 1300 nm wavelengths, with camera speeds up to 250 kHz. Addition of a 1600 nm model offers greater depth penetration with high contrast for highly scattering tissues and materials, with applications in cardiology, neurology, dermatology, dentistry, and non-destructive testing. The Cobra 1600 OCT spectrometer utilizes a 240 nm bandwidth centered at 1570 nm to ...

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      Mentions: Wasatch Photonics

    16. New Research Finds Abbott's Optical Coherence Tomography Imaging Changed Treatment Decisions in 88% of Artery Blockages

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      New Research Finds Abbott's Optical Coherence Tomography Imaging Changed Treatment Decisions in 88% of Artery Blockages

      Abbott (NYSE: ABT ) today announced new data from the company's LightLab Initiative that showed optical coherence tomography (OCT) imaging significantly changes how physicians decide to treat a vessel compared to traditional angiography by providing physicians improved visualization within a patient's blood vessels. Data from the study revealed physicians altered their treatment strategy in 88% of coronary artery blockages based on new information provided by OCT. Using laser technology, OCT captures high-resolution images inside a patient's arteries, displaying the type and severity of disease in the vessel, as well as enabling more accurate measurements to determine how the ...

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      Mentions: Abbot Hiram G. Bezerra

    17. Postdoctoral positions for ophthalmic imaging at Johns Hopkins

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      Postdoctoral positions for ophthalmic imaging at Johns Hopkins

      Description: We are seeking outstanding candidates for two postdoctoral positions on cutting‐edge 3D ophthalmic imaging projects funded by NIH. The first position focuses on visible light optical coherence tomography (vis‐OCT) , a new ophthalmic imaging technique that offers ultrahigh depth resolution, capillary level oximetry, and rich retinal scattering spectroscopy. The second position focuses oblique scanning laser ophthalmoscopy (oSLO), a “fluorescent‐version” of OCT that implements light sheet microscopy in the eye and uniquely allowing high speed volumetric retinal imaging. The candidates will learn and be responsible for the end‐to‐end design of device, imaging, and data processing. We ...

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      Mentions: Johns Hopkins University National Institutes of Health Ji Yi

    18. Massachusetts General Hospital Receives NIH Grant for Blood Flow-Based Guidance and Diagnostics Using OCT

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      Massachusetts General Hospital Receives NIH Grant for Blood Flow-Based Guidance and Diagnostics Using OCT

      Massachusetts General Hospital Receives a 2020 NIH Grant for $174,174 for Blood Flow-Based Guidance and Diagnostics Using OCT. The principal investigator is Nestor Uribe-Patarroyo. Below is a summary of the proposed work. Diseases diagnosed with assessment of blood flow account for 29% of deaths in the US and are leading causes of premature morbidity, including visual disorders which carry an economic burden of $35 bil- lion per year. The heart disease with the most impact on public health is coronary artery disease (CAD); more than one million percutaneous coronary interventions (PCI) are performed in the US ev- ery year ...

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      Mentions: National Institutes of Health Massachusetts General Hospital

    19. Aqua Licensing LLC Retained to Explore the Sale of of the Compact Imaging OCT Patent Portfolio

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      Aqua Licensing LLC Retained to Explore the Sale of of the Compact Imaging OCT Patent Portfolio

      Aqua Licensing LLC has been retained to explore the sale of of the Compact Imaging OCT patent portfolio. This patent portfolio is developed, owned and offered for sale by Compact Imaging, Inc., the developers of MRO™ (multiple reference OCT) technology. The portfolio anticipated the development of features that are now market standard in Optical Coherence Tomography (“OCT”) and Fundus imaging devices and applications. These features are deployed industry-wide in ophthalmology and have become the clinical standard of care in ophthalmic diagnostic imaging. Claim charts are available under NDA that illustrate the reads on products with covered revenue in excess of ...

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      Mentions: Compact Imaging, Inc

    20. PhD and postdoctoral positions in Optical Imaging and Biomechanics at University of Houston

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      PhD and postdoctoral positions in Optical Imaging and Biomechanics at University of Houston

      The Biomedical Optics Laboratory ( http://bol.egr.uh.edu ) in the Department of Biomedical Engineering at the University of Houston, TX invites applications for one or more pre- and post-doctoral positions in the area of optical imaging, photoacoustics, and biomechanics. Extensive experience in one of the following areas is required: optical coherence tomography (OCT), opto(photo)acoustics, light-sheet microscopy (instrumentation and software development), optical elastography/biomechanics, and Brillouin Spectroscopy. The successful applicants will join a dynamic team to work on projects such as optical methods to study tissue (ocular, skin, heart) biomechanics and development of advanced optical methods for developmental ...

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      Mentions: Kirill V. Larin University of Houston

    21. BIGSS 2020 – Virtual Summer School August 25th – 29th 2020

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      BIGSS 2020 – Virtual Summer School August 25th – 29th 2020

      BIGSS 2020 summer school will go virtual this year . The deadline for abstract submission is Wednesday 18 th of July 2020 and authors will be notified by the 28 th of July 2020 . BIGSS 2020 will include Five day lectures by renowned researches (Details of topics given below) Highly interactive online poster sessions Live Q&A sessions within the web conferencing platform The registration fees have been considerably reduced to enable remote access to the widest audience as possible, namely: - The registration fee for attendees (not presenting) is waived: 0€. This includes a free access to the Summer School. - The ...

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      Mentions: University of Toronto University of Montreal University of Pennsylvania

    22. Home OCT longitudinal home-based study with patient self-operated device has begun

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      Home OCT longitudinal home-based study with patient self-operated device has begun

      Notal Vision is proud to announce the enrollment of patients in the first longitudinal home-based study with its investigational home optical coherence tomography (OCT) remote monitoring device. The study will explore the daily dynamics of retinal fluid in patients receiving anti-VEGF treatment for wet age-related macular degeneration (AMD). The Home OCT System pipeline technology is designed to provide home-based, patient-initiated retinal OCT scans to support the management of patients with wet AMD, complementing existing standard of care treatments as well as emerging longer acting drugs and drug delivery systems. “The study is an important milestone for our Home OCT pipeline ...

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      Mentions: FDA National Eye Institute Kester Nahen

    23. University of Washington Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy

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      University of Washington Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy

      University of Washington Receives a 2020 NIH Grant for $575,178 for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy. The principal investigator is Ruikang Wang. Below is a summary of the proposed work. The increasing incidence of diabetes in the US population and the inertial wave of aging in Americans will ensure that diabetic retinopathy (DR) remains one of the principal threats to the sight of adult patients and a significant management challenge for the clinical community. It is now clear that the peripheral retina is the site of pathology in many vision-threatening eye diseases, including ...

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      Mentions: National Institutes of Health University of Washington Ruikang K. Wang

    24. Case Western Reserve University Receives NIH Grant for Noninvasive Assessment of the Cornea by Diffusion OCT

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      Case Western Reserve University Receives NIH Grant for Noninvasive Assessment of the Cornea by Diffusion OCT

      Case Western Reserve University Receives a 2020 NIH Grant for $560,406 for Noninvasive Assessment of the Cornea by Diffusion OCT. The principal investigator is Andrew Rollins. Below is a summary of the proposed work. Keratoconus is a degenerative disease of the cornea that is a major cause of reduced vision-related quality of life in the United States, often leading to corneal transplantation. Ectasia after refractive surgery is a vision-threatening complication that can occur in apparently low-risk patients despite current screening technology. The biomechanical properties of the cornea play a central role in these diseases, but diagnostics are still rooted ...

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      Mentions: Andrew M. Rollins National Institutes of Health Case Western Reserve University
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