1. Optical Coherence Tomography News

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    1. Children's Hospital of Philadelphia Receives NIH Grant for Biomarkers of Vision Loss in Children with Optic Pathway Gliomas

      Children's Hospital of Philadelphia Receives NIH Grant for Biomarkers of Vision Loss in Children with Optic Pathway Gliomas

      Children's Hospital of Philadelphia Receives a 2020 NIH Grant for $611,652 for Biomarkers of Vision Loss in Children with Optic Pathway Gliomas. The principal investigator is Rogbert Avery. Below is a summary of the proposed work. Low-grade gliomas are the most common brain tumor in children and frequently involve the optic nerve, chiasm, and tract—so they are referred to as optic pathway gliomas (OPGs). OPGs cause vision loss, typically between 1 and 8 years of age, resulting in lifelong disability as well as reduced academic and vocational achievement. The long term goal of this research proposal is ...

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    2. Massachusetts Eye and Ear Infirmary Receives NIH Grant for Human Cochlear Structure & Function

      Massachusetts Eye and Ear Infirmary Receives NIH Grant for Human Cochlear Structure & Function

      Massachusetts Eye and Ear Infirmary Receives a 2020 NIH Grant for $544,982 for Human Cochlear Structure & Function. The principal investigator is Hideko Nakajima . Below is a summary of the proposed work. Although the inner workings of the cochlea are responsible for the most fundamental aspects of hearing, including hearing sensitivity and frequency tuning, our direct knowledge of human cochlear mechanics is limited. This lack of information has forced researchers to rely on animal experiments to make inferences about cochlear behavior in humans, under the assumption that the motions of the cochlear partition (CP), including the basilar membrane (BM) and ...

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    3. UIUC Receives NIH Grant for A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)

      UIUC Receives NIH Grant for A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)

      University of Illinois at Urbana-Champaign Receives a 2020 NIH Grant for $445,996 for A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD). The principal investigator is Liang Gao. Below is a summary of the proposed work. An imaging modality that allows for fast, simultaneous, noninvasive probing of both 3D cellular resolution retinal morphology by optical coherence tomography (OCT) and molecular-specific functions by autofluorescence (AF) could substantially improve both basic understanding and the early diagnosis of age- related macular degeneration (AMD), the leading cause of blindness in the developed world. The evaluation and management of ...

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    4. Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network

      Novel Tunable Lasers for Optical Coherence Tomography: Marie Curie Early Stage Positions to train towards PhD in an European Innovative Training Network

      We are recruiting for a PhD Studentship in the fields of Optics and Laser Physics, with emphasis on optical coherence tomography for a period of 36 months starting up to 31 January 2021, within the Applied Optics Group, School of Physical Sciences. These are supported by the Marie Curie Innovative Training Network scheme, 860807, EU funded, jointly organised with 14 other universities, companies and hospitals in Europe. You will spend time at the University of Kent and at the other beneficiaries or associated partners. Supervision will be provided in an European setting where specialized and complementary training will be provided ...

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    5. Boston Medical Center Receives NIH Grant for Microvasculature in Colon Field Carcinogenesis: Clinical-Biological Implications

      Boston Medical Center Receives NIH Grant for Microvasculature in Colon Field Carcinogenesis: Clinical-Biological Implications

      Boston Medical Center Receives a 2020 NIH Grant for $683,687 for Microvasculature in Colon Field Carcinogenesis: Clinical-Biological Implications. The principal investigator is Hemat Roy. Below is a summary of the proposed work. The overall goal of this project is to develop a rectal probe for minimally intrusive highly accurate risk stratification with the vision of utilizing it for a precision medicine approach to colon cancer screening and also potentially chemoprevention (companion biomarker). We will employ cutting edge biophotonics (ISOCT) and biological approaches combined with large scale human studies to elucidate the clinical/biological implications of mucosal early increase in ...

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    6. Columbia University Receives NIH Grant for Auditory Mechanics and Cochlear Amplification

      Columbia University Receives NIH Grant for Auditory Mechanics and Cochlear Amplification

      Columbia University Receives a 2020 NIH Grant for $428,832 for Auditory Mechanics and Cochlear Amplification. The principal investigator is Elizabeth Olson. Below is a summary of the proposed work. Sound input to the inner ear (cochlea) causes a frequency-segregated wave-pattern of sensory tissue motion that conveys sound information to the auditory neurons, leading to hearing. A currently untreatable aspect of hearing impairment is the deterioration of the cochlea's ability to sharply segregate sound by frequency. The cochlea's healthy frequency tuning is largely provided by the cochlear amplifier, an outer-hair-cell-driven, place-frequency-localized electromechanical engine that is both powerful and ...

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    7. ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership

      ZEISS Medical Technology Announces Changes in Ophthalmic Devices Executive Leadership

      Effective 1 May 2020, Jim Mazzo will retire from his position as President Ophthalmic Devices and Head of the Ophthalmic Devices Strategic Business Unit for ZEISS. He will continue to support ZEISS as an advisor. With over forty years in the ophthalmic industry, Jim has successfully transformed ZEISS Global Ophthalmic Devices as the number two industry leader in Ophthalmology by creating a strong customer focused organization within his three plus years with ZEISS. "I am very proud of what we have accomplished for customers and employees and pleased to hand over responsibility to Euan and the team. With this team ...

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    8. Cylite receives ISO 13485 Certification

      Cylite receives ISO 13485 Certification

      Cylite Pty Ltd, a developer and manufacturer of 4 th Generation OCT systems for Ophthalmology and Optometry, is pleased to announce that it has been awarded International Organization for Standardization (ISO) 13485:2016 certification for medical device quality management systems (QMS) following review by BSI. ISO 13485:2016 is an internationally recognized quality standard specific to the medical device industry. ISO 13485 certification affirms to Cylite’s patients and partners that the company is providing the best quality management systems and regulatory compliance for its 4 th generation OCT platform. Yameena Ratnayake, Cylite’s Quality Manager commented,” We are very ...

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    9. Postdoctoral researcher on OCT imaging of atherosclerosis

      Postdoctoral researcher on OCT imaging of atherosclerosis

      Published Deadline Location 26 Feb 24 Mar Rotterdam JOB DESCRIPTION Atherosclerosis is an inflammatory and lipid-driven disease of the artery walls. In the coronary circulation, it is the main cause of ischemic heart disease and kills approximately 10 million people per year through myocardial infarctions and subsequent heart failure. Treatment of coronary artery disease by stent implantation can be guided by intravascular imaging with catheter-based optical coherence tomography (IV-OCT). In this project we will realize an OCT system that can perform spectroscopic imaging for identification of atherosclerotic lesion composition. Lipid-rich plaques are associated with worse long-term outcomes for patients. Knowledge ...

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    10. University of Alabama at Birmingham Receives NIH Grant for The Mechanisms Underlying Abnormal Mucus and Its Clearance in the cystic Fibrosis Rat

      University of Alabama at Birmingham Receives NIH Grant for The Mechanisms Underlying Abnormal Mucus and Its Clearance in the cystic Fibrosis Rat

      University of Alabama at Birmingham Receives a 2020 NIH Grant for $135,570 for The Mechanisms Underlying Abnormal Mucus and Its Clearance in the cystic Fibrosis Rat. The principal investigator is Susan Briket. Below is a summary of the proposed work. Abnormal mucociliary clearance (MCC) is a critical component of cystic fibrosis (CF) lung disease, especially in the presence of infection; however, the mechanisms responsible for the defect are not well understood. Until recently, evaluation of this question has been primarily limited to cell culture models which do not replicate the complex nature of the airway surface or include contributions ...

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    11. Post-doctoral Associate Positions in Biophotonics / Biomedical Optical Imaging at Washington University in St. Louis

      Post-doctoral Associate Positions in Biophotonics / Biomedical Optical Imaging at Washington University in St. Louis

      Position description: We are looking for highly motivated individuals to develop advanced optical imaging techniques for novel biomedical applications in vitro and/or in vivo . Successful candidates will have opportunities to collaborate with top academic and industry partners . Compensation is commensurate with experience. Qualifications: Ph.D. in Biomedical Engineering / Bioengineering, Electrical Engineering, Physics, Applied Physics or related fields. Clinical experience with ophthalmic imaging, and hands-on hardware and programming experience with optical coherence tomography (OCT), including spectral-domain and swept-source OCT, is preferred. Good publication record and communication skills. Research areas: The candidate is expected to work on one of the following ...

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    12. Biophotonics and Imaging Graduate Summer School to be held on August 2020 at National University of Ireland, Galway

      Biophotonics and  Imaging  Graduate  Summer  School to be held on August 2020 at National University of Ireland, Galway

      Dates: August 25th - 29th 2020 This is our eight Biophotonics and Imaging Graduate Summer School. It is an important opportunity for graduate students in 2020 to access the kind of close contact with leading professors that only this kind of environment facilitates. Tutors for BIGSS 2020 will include: Martin Booth (Oxford): Advanced Microscopy Steve Jacques (Washington): Tissue Optics Caroline Boudoux (Montreal): Endoscopy David Sampson (Surrey): OCT Sarah Bohndiek (Cambridge): Photoacoustics Arjun Yodh (U. Penn): Brain-Neurophotonics Brian Wilson (Toronto): Photo Medicine, Radiation Medicine and Nano Medicine Wei Chen (Oklahoma): Photoimmunology

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    13. Kylee Hall joins Cylite as VP Sales and Marketing

      Kylee Hall joins Cylite as VP Sales and Marketing

      ylite Pty Ltd, a company developing the next generation of diagnostic OCT systems for Ophthalmology and Optometry, is pleased to announce the appointment of Kylee Hall as Vice President, Sales and Marketing. Ms Hall is a medical device industry expert and brings more than 13 years of senior leadership in sales, marketing and corporate management. She has a record of accomplishment in executing best practice business, sales and marketing strategies in Ophthalmic and Surgical devices. "I am delighted to welcome Kylee to the Cylite executive team,” stated Dr. Steve Frisken, Chief Executive Officer of Cylite. “I am confident that her ...

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    14. Conavi Medical and Japan Lifeline Announce MHLW Approval of Novasight Hybrid Intravascular Imaging System for Japanese Market

      Conavi Medical and Japan Lifeline Announce MHLW Approval of Novasight Hybrid Intravascular Imaging System for Japanese Market

      Conavi Medical Inc. and Japan Lifeline are pleased to announce that they have received regulatory approval from the Ministry of Health, Labor and Welfare (MHLW) in Japan for the Novasight Hybrid TM intravascular imaging system. The Novasight Hybrid system is the world’s first clinical system capable of providing both intravascular ultrasound (IVUS) and optical coherence tomography (OCT) on a single imaging catheter. The system also has Health Canada approval and FDA 510(k) clearance in the USA. Japan Lifeline is the exclusive distributor for this technology in Japan. Dr. Brian Courtney, Conavi Medical’s Chief Executive Officer, comments that ...

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    15. University of Illinois at Chicago Receives NIH Grant for Functional Tomography of Neurovascular Coupling Interactions in Healthy and Diseased Retinas

      University of Illinois at Chicago Receives NIH Grant for Functional Tomography of Neurovascular Coupling Interactions in Healthy and Diseased Retinas

      University of Illinois at Chicago Receives a 2020 NIH Grant for $ 352,927 for Functional Tomography of Neurovascular Coupling Interactions in Healthy and Diseased Retinas. The principal investigator is Xincheng Yao. Below is a summary of the proposed work. This project is to investigate spatiotemporal interactions between neural activities and hemodynamic changes in the retina, and to explore quantitative mapping of retinal neurovascular coupling defects caused by neurodegenerative diseases. Retinal neurodegenerative diseases, such as age-related macular degeneration (AMD), retinitis pigmentosa (RP), diabetic retinopathy (DR) and glaucoma, can produce severe vision losses if medical interventions cannot be provided promptly. As one ...

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    16. Dyad Medical Receives NIH Grant for Software For OCT Analysis of Vascular Stents

      Dyad Medical Receives NIH Grant for Software For OCT Analysis of Vascular Stents

      Dyad Medical Receives a 2020 NIH Grant for $ 1,085,076 for Software For OCT Analysis of Vascular Stents. The principal investigator is Ronny Shalev. Below is a summary of the proposed work. Dyad Medical, Inc. will create intravascular Optical Coherence Tomography (IVOCT) software for clinical, live time determination of stent apposition and for offline analysis of stent implantation. Every year, 100s of thousands of patients in the US are treated with intravascular stents creating an opportunity for both solutions. Although advancements such as drug eluting metal stents hinder restenosis, there remains significant room for improvement. Stent design parameters include ...

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    17. Oregon Health and Science University Receives NIH Grant for Application of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases

      Oregon Health and Science University Receives NIH Grant for Application of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases

      Oregon Health and Science University Receives a 2020 NIH Grant for $493,238 for Application of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases. The principal investigator is David Huang. Below is a summary of the proposed work. Optical coherence tomography (OCT) is uniquely able to achieve micron depth resolution while imaging a large 3-dimensional (3D) volume. This enables 3D imaging and precise measurements in the anterior segment of the eye, including the cornea, conjunctiva, sclera, anterior chamber, iris, and crystalline lens. Anterior segment OCT is already widely used in ophthalmology. But a number of high-impact applications were held back ...

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    18. Post Doc Position for Optical Coherence Tomography at the Medical University Vienna

      Post Doc Position for Optical Coherence Tomography at the Medical University Vienna

      A PostDoc position is available from March 1, 2020 at the Center for Medical Physics and Biomedical Engineering, Medical University of Vienna. We offer a research position in the field of biomedical imaging with strong interdisciplinary collaboration. Our research group is developing novel coherent biomedical imaging methods based on parallel OCT and digital adaptive optics to overcome the conventional resolution limits and to pave the way from pure structural to functional tissue and cell metabolic imaging. This involves profound knowledge of theoretical and experimental optics, system engineering, data and image processing, as well as hands-on experience in modern biomedical optics ...

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    19. Cornell University Receives NIH Grant for Three-Dimensional Mechano-Microscopy of Stem Cell Niche

      Cornell University Receives NIH Grant for Three-Dimensional Mechano-Microscopy of Stem Cell Niche

      Cornell University Receives a 2020 NIH Grant for $191,422 for Three-Dimensional Mechano-Microscopy of Stem Cel Niche. The principal investigator is Steven Adie. Below is a summary of the proposed work. Biophysical properties of cellular microenvironments can act to direct the self-renewal and differentiation fate outcomes of stem cells in multiple tissue types. As an example, the stem cells resident in skeletal muscles (MuSCs, also called satellite cells) are highly sensitive to elasticity of their surrounding “niche” microenvironment. In culture models, elastic substrates corresponding to the more stiff microenvironments observed in muscle aging and diseases such as muscular dystrophy can ...

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    20. AI-based retinal fluid analytics of serial Notal Vision home OCT images offers insights into retinal disease dynamics

      AI-based retinal fluid analytics of serial Notal Vision home OCT images offers insights into retinal disease dynamics

      Longitudinal data on retinal imaging of age-related macular degeneration (AMD) patients using the final form factor of Notal Vision’s home OCT (NOTAL-OCT V3.0) was presented at the Angiogenesis, Exudation, and Degeneration meeting in Miami. The pipeline technology is designed to use home-based, patient-initiated retinal OCT scans to support the management of patients with exudative AMD, complementing existing standard of care as well as emerging longer acting drugs and drug delivery systems. “This is the first time nano-liter scale quantities of intra- and subretinal fluid have been tracked over time based on home OCT images and deep learning retinal ...

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    21. Researchers at OCT Medical Imaging Inc., along with researchers at Caltech and UCSD Develop Genetically Encodable and Acoustically Erasable Contrast Reagent for Optical Coherence Tomography

      Researchers at OCT Medical Imaging Inc., along with researchers at Caltech and UCSD Develop Genetically Encodable and Acoustically Erasable Contrast Reagent for Optical Coherence Tomography

      Dr. Ramalingam's group at OCT Medical Imaging in collaboration with researchers at Caltech and UCSD have developed, first genetically encodable and acoustically erasable contrast reagent for Optical Coherence Tomography (OCT) . Here, we introduce gas vesicles, a class of naturally evolved gas-filled protein nanostructures, as genetically encodable OCT contrast agents. The differential refractive index of their gas compartments relative to surrounding aqueous tissue and their nanoscale motion enables gas vesicles to be detected by static and dynamic OCT. Furthermore, the OCT contrast of gas vesicles can be selectively erased in situ with ultrasound, allowing unambiguous assignment of their location. In ...

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    22. PhotoniCare's TOMi Scope takes Top Prize at SPIE and Photonics Media Prism Awards

      PhotoniCare's TOMi Scope takes Top Prize at SPIE and Photonics Media Prism Awards

      PhotoniCare, Inc., a company dedicated to revolutionizing healthcare by providing physicians with better diagnostic tools, today announced the company’s TOMi ™ Scope was awarded best healthcare product at the 12th Annual Prism Awards in San Francisco. The Prism Awards is an annual international competition that honors the best new optics and photonics products on the market. Since 2008, SPIE, along with media partner Photonics Media, has presented awards to companies and individuals that are creating products that make a difference, solve problems, and improve life through photonics. The Prism Awards reflect the exponential growth, exciting developments, and rich technical innovations ...

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    23. Postdoctoral opening in quantitative retinal imaging and analysis at University of Illinois at Chicago

      Postdoctoral opening in quantitative retinal imaging and analysis at University of Illinois at Chicago

      A postdoctoral position is available in the Biomedical Optics and Functional Imaging group ( https://yaolab.bioe.uic.edu ) within the Department of Bioengineering, University of Illinois at Chicago. Our research lab is working on ultra-wide field fundus photography, functional optical coherence tomography (OCT), super-resolution ophthalmoscopy, retinal image analysis and classification. The postdoctoral fellow will be responsible for quantitative analysis of OCT/OCTA and machine learning based image classification. This position will be supported by a NIH project entitled differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathy . The successful candidate should have a Ph.D. degree in ...

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