1. Optical Coherence Tomography News

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    1. Massachusetts General Hospital Receives NIH Grant for The Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives NIH Grant for The Center for Biomedical OCT Research and Translation

      Massachusetts General Hospital Receives 2014 NIH Grant For $1,449,151 for The Center for Biomedical OCT Research and Translation. The principal investigator is Brett Bouma. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Optical coherence tomography (OCT) has evolved into a powerful microscopy technique for a broad range of applications in biology and clinical medicine. It can safely be used to image biological tissue with high resolution and can easily integrate flexible, narrow diameter optical fiber probes for imaging internal organs. Recent advances have increased OCT imaging speeds by nearly ...

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    2. Postdoctoral Research Associate Opening at University of Liverpool

      Postdoctoral Research Associate Opening at University of Liverpool

      Postdoctoral Research Associate £31,644 - £36,661 pa Faculty of Science and Engineering, Institute of Electrical Engineering and Electronics, Department of Electrical Engineering and Electronics Location: University Campus Ref: R-585803/WWW Closing date for receipt of applications: Fri, 22 Aug 2014 17:00:00 BST To undertake a project “ I ntelligent Manufacturing of Pharmaceutical Film Coating Using Terahertz Pulsed Imaging, Optical Coherence Tomography and Numerical Modelling ” in collaboration with Cambridge University. You will primarily focus on the development and integration of an optical coherence tomography (OCT) sensor for online monitoring and quality control of pharmaceutical coating process. The duties include ...

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    3. Astronaut Using Optical Coherence Tomography during an Ocular Health vision Test on the International Space Station

      Astronaut Using Optical Coherence Tomography during an Ocular Health vision Test on the International Space Station

      Flight Engineer Alexander Gerst uses the Optical Coherence Tomography camera during an Ocular Health vision test in the Harmony node of the International Space Station. Commander Steve Swanson (left) assists Gerst. Image credit: NASA. Larger image (1 MB): http://www.nasa.gov/sites/default/files/oh_vision_test.jpg

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    4. Michelson Diagnostics to present at Fortbildungswoche, Munich

      Michelson Diagnostics to present at Fortbildungswoche, Munich

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, today announces that leading experts in the use of optical technology in dermatology will be presenting the benefits of multi-beam OCT at the 24th Annual Education Week for Practical Dermatology and Venereology, known as Fortbildungswoche, in Munich, Germany, 19-25 July 2014. The conference session on ‘Evidence for OCT diagnostics’ will take place at 12:15-13:15, Forum 9, on Friday 25th July. The presentations include: Optical coherence tomography scientific fundamentals and applications, Dr. Martina Ulrich Optical coherence tomography for basal cell carcinoma, Prof. Dr ...

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    5. University of California at San Diego Receives at 2014 NIH Grant for Computational Ophthalmology

      University of California at San Diego Receives at 2014 NIH Grant for Computational Ophthalmology

      University of California at San Diego Receives at 2014 NIH Grant for $188,364 for Computational Ophthalmology. The principal investigator is Linda Zangwill. The program began in 2014 and ends in 2014. Below is a summary of the proposed work. COMPUTATIONAL OPHTHALMOLOGY MODULE OVERVIEW At UCSD, structural imaging instruments such as the spectral domain optical coherence tomography (SD-OCT) and functional instruments are used extensively in animal (Drs. Weinreb, Freeman, Yu, La Spada, Zhang, Freeman) and human studies of glaucoma (Drs. Weinreb, Ju, Lindsay, Zangwill, Medeiros, Balasubramanian) and retinal disease (Drs. Freeman, Yu, Bartsch, Zhang, Cheng). The recent development and commercialization ...

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    6. University of California at San Diego receives NIH Grant for Studying Animal Structure and Function

      University of California at San Diego receives NIH Grant for Studying Animal Structure and Function

      University of California at San Diego received a 2014 NIH Grant for $167,628 for Animal Structure and Function. The principal investigator is Dirk-Uwe Bartsch. The program began in 2014 and ends in 2015. Below is a summary of the proposed work. The Animal Structure and Function Module will provide new centralized space for state-of-the-art structural and functional animal testing with a dedicated animal care technician to conduct the testing and to train investigators and their staff on the use of the new equipment. The recent growth in the number of faculty in the Department of Ophthalmology conducting animal structure ...

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    7. Academic Post Doc Position in Biomedical Optics at the Medical University Vienna

      Academic Post Doc Position in Biomedical Optics at the Medical University Vienna

      An academic PostDoc position is available from September 1, 2014 in the Biomedical Optics Division, Center for Medical Physics and Biomedical Engineering . Depending on the candidates’ research record the position may be continued as tenure track after the first two to three years. We offer an academic position at an international highly recognized research institute in the field of biomedical imaging with strong interdisciplinary (door to door) collaboration with clinicians as well as biologists. Our research group is developing novel coherent biomedical imaging methods to overcome the conventional resolution limits and to pave the way from pure structural to functional ...

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    8. Post-Doc Job Offer in Clinical Applications of Image Processing at Duke University

      Post-Doc Job Offer in Clinical Applications of Image Processing at Duke University

      There is an immediate opening at Duke University Biomedical Engineering Department for a Postdoctoral Research Associate interested in interdisciplinary applications of image processing with emphasis on Optical Coherence Tomography (OCT) and adaptive optics. Post-doc will be supervised by Prof. Sina Farsiu in collaboration with Prof. Joseph A. Izatt and other senior professors from Duke University Electrical and Computer Engineering Department, Biomedical Engineering Department and Duke University School of Medicine. Requirement: PhD in EE, BME, or CS. No previous experience in ophthalmic sciences or optical coherence tomography is necessary. The candidate must have a demonstrated strong background in image processing, as ...

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    9. Physical Sciences Receives NIH Grant for Optical Coherence Tomography Based on Freeze Drying Microscopy

      Physical Sciences Receives NIH Grant for Optical Coherence Tomography Based on Freeze Drying Microscopy

      Physical Sciences Incorporated Received a 2014 NIH Grant for $538,335 for Optical Coherence Tomography Based on Freeze Drying Microscopy. The principal investigator is Mircea Mujat. The program began in 2009 and ends in 2015. Below is a summary of the proposed work. Physical Sciences Inc. (PSI), in collaboration with the University of Connecticut (UConn), proposes to develop the 2nd generation of an advanced 3D freeze-drying microscopy (FDM) system to advance the understanding of freeze-drying and to enable the development of efficient commercial freeze drying processes. During the Phase I program PSI demonstrated the application of Optical Coherence Tomography (OCT ...

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    10. Baylor College of Medicine Receives NIH Grant for Studying Biomechanics of Early Mammalian Cardiogenesis

      Baylor College of Medicine Receives NIH Grant for Studying Biomechanics of Early Mammalian Cardiogenesis

      Baylor College of Medicine Received a 2014 NIH Grant for $378,647 for Biomechanics of Early Mammalian Cardiogenesis. The principal investigator is Irina Larina. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Congenital heart defects are among the most common birth defects and the leading cause of death in children born with congenital defects. Understanding how the early embryonic heart functions and what regulatory mechanisms are involved in early cardiogenesis is highly important for advancement of heart defects research. Biomechanical stimuli, including blood flow and heart contraction, are important regulators of ...

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    11. University of Houston Receives NIH Grant for Optical Coherence Elastography of the Cornea

      University of Houston Receives NIH Grant  for Optical Coherence Elastography of the Cornea

      University of Houston Received a 2014 NIH Grant for $388,129 for Optical Coherence Elastography of the Cornea. The principal investigator is Kirill Larin. The program began in 2012 and ends in 2015. Below is a summary of the proposed work. The fundamental physical properties of the outer tunic of the eye determine the structural characteristics of the ocular globe and may be altered in several disease states including axial elongation in myopia, pathological deformation in keratoconus, and iatrogenic keratoectasia following corneal refractive surgery. These biomechanical tissue characteristics not only influence our clinical interpretation of diagnostic tests, e.g. measurement ...

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    12. MIT Receives NIH Grant for Optical Biopsy Using Optical Coherence Tomography

      MIT Receives NIH Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Received a 2014 NIH Grant for $302,576 for Optical Biopsy Using Optical Coherence Tomography. THe principal investigator is James Fujimoto. The program began in 1997 and ends in 2019. Below is a summary of the proposed work. This is a multidisciplinary collaboration between investigators at the Massachusetts Institute of Technology and the VA Boston Healthcare System integrating imaging technology research, clinical imaging studies, medical device development and animal imaging studies. Esophageal cancer is a lethal malignancy, with a five-year survival rate of 16%. Barrett's esophagus (BE) and dysplasia are precursors to esophageal adenocarcinoma (EAC ...

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    13. Yale University Receives NIH Grant for Development of a New Light Sources for Parallel Optical Coherence Tomography

      Yale University Receives NIH Grant for Development of a New Light Sources for Parallel Optical Coherence Tomography

      Yale University Receivesd a 2014 NIH Grant for $201,881 for Development of a New Light Sources for Parallel Optical Coherence Tomography. The principal investigator is Michel Choma. The program began in 2013 and ends in 2015. Below is a summary of the proposed work. The ability of optical coherence tomography (OCT) to perform high-speed, micron-scale, cross-sectional imaging has transformed ophthalmic medicine and has the potential to transform cardiovascular, gastrointestinal, pulmonary, and dermatological medicine. Current OCT systems use raster scanning, a serial method for acquiring depth reflectivity profiles at different locations on a sample. Shifting the paradigm fro serial to ...

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    14. UIUC Receives NIH Grant for Partnership for Primary Care Imaging

      UIUC Receives NIH Grant for Partnership for Primary Care Imaging

      University of Illinois at Urbana Champaign Received a 2014 NIH Grant for $933,337 for Partnership for Primary Care Imaging. The principal investigator is Stephen Boppart. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Primary Care Medicine, including Family Practice and Pediatrics, has traditionally relied on physical exam skills and simplistic instruments for critical diagnostic decision making, monitoring, and referral to medical specialists. The otoscope and ophthalmoscope are two historical and ubiquitous instruments that largely only illuminate and magnify tissue surfaces in the ear and eye, respectively. This Partnership will develop ...

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    15. UC Riverside Receives a 2014 NIH Grant for Studying Optical Detection of the Pre-Seizure State

      UC Riverside Receives a 2014 NIH Grant for Studying Optical Detection of the Pre-Seizure State

      UC Riverside Received a 2014 NIH Grant for $437,523 for Studying Optical Detection of the Pre-Seizure State. The principal investigator is Devin Binder. The program began in 2-012 and ends in 2016. Below is a summary of the proposed work. Reliable means of detecting changes which occur during the "pre-seizure state" could serve as a method of seizure prediction, a benchmark in epilepsy research (NIH Curing Epilepsy Conferences, 2000 and 2007). Our preliminary data indicate pre-seizure constriction in brain extracellular space (ECS) accompanied by reduction in near-infrared (NIR) optical scattering prior to detection of seizure by electroencephalography (EEG). The ...

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    16. Visdex Corporation Received a 2014 NIH Grant for Phase Contrast OCT for Non-Invasive Imaging of Retinovascular Disease

      Visdex Corporation Received a 2014 NIH Grant for Phase Contrast OCT for Non-Invasive Imaging of Retinovascular Disease

      Visdex Corporation Received a 2014 NIH Grant for $496,465 for Phase Contrast OCT for Non-Invasive Imaging of Retinovascular Disease. The principal investigator is Scott Frasier. The program began in 2010 and ends in 2015. Below is a summary of the proposed work. Since its introduction in the 1960's, fluorescein angiography (FA) has been the gold standard for retinal vascular diagnosis. However, FA is costly, invasive, and time-consuming, which limits its usefulness as a screening tool. As a potential non-invasive alternative to FA for diagnosing retinovascular disease, we have developed an imaging method called phase contrast optical coherence tomography ...

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    17. Feature Of The Week 6/29/14: Development of a high power supercontinuum source in the 1.7 um wavelength region for highly penetrative ultrahigh-resolution optical coherence tomography

      Feature Of The Week 6/29/14: Development of a high power supercontinuum source in the 1.7 um wavelength region for highly penetrative ultrahigh-resolution optical coherence tomography

      Optical coherence tomography (OCT) is an essential imaging technique especially in ophthalmology. However, the shallow penetration depth of about 1-2 mm limits the expansion of OCT applications. Recently, the OCT systems operating in 1.7 um wavelength region have been demonstrated to improve the penetration depth. In the longer wavelength region, the signal attenuation due to Rayleigh scattering is reduced compared to that in the conventional 0.8-1.3 um wavelength region. In this work, the authors developed a high power supercontinuum (SC) source at a center wavelength of 1.7 um to demonstrate highly penetrative ultrahigh resolution (UHR) OCT ...

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    18. PhD position in Dental Optical Coherence Tomography Department of Odontology at University of Copenhagen.

      PhD position in Dental Optical Coherence Tomography Department of Odontology at University of Copenhagen.

      PhD fellowship in dental optical coherence tomography - Department of Odontology Applications are invited for a PhD Fellowship at the Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen. The candidate will work in the area of digital dental scanning with focus on optical coherence tomography (OCT). The position is for a 3-year period and will commence on 1 September 2014 or as soon as possible thereafter. Project description The project is part of a research programme between industry, Technical University of Denmark (DTU) and Department of Odontology, University of Copenhagen. The objective of the project is to ...

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    19. Feature Of The Week 6/22/14: Feasibility of Intracoronary Frequency Domain Optical Coherence Tomography Derived Fractional Flow Reserve for the Assessment of Coronary Artery Stenosis

      Feature Of The Week 6/22/14: Feasibility of Intracoronary Frequency Domain Optical Coherence Tomography Derived Fractional Flow Reserve for the Assessment of Coronary Artery Stenosis

      Frequency domain optical coherence tomography (FD-OCT) provides cross-sectional images of coronary arteries and deployed stents with micron resolution and measures lumen dimensions with excellent reproducibility. FD-OCT combined with blood flow resistances model can overcome many limitations of conventional measures of stenosis severity based on quantitative coronary angiography (QCA) and intravascular ultrasound (IVUS). The aim of this feasibility study was to investigate the relationship between pressure derived fractional flow reserve (FFR) and FD-OCT derived FFR, a new method for quantitative measure of stenosis severity that estimates the blood flow resistance and microvascular resistance of the vessel segments imaged by FD-OCT. 26 ...

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    20. UC Irvine Receives at 2014 NIH Grant for Evaluation of Obstructive Sleep Apnea with Long Range 3D Endoscopic FD-OCT

      UC Irvine Receives at 2014 NIH Grant  for Evaluation of Obstructive Sleep Apnea with Long Range 3D Endoscopic FD-OCT

      University of California Irvine Receives at 2014 NIH Grant for $122,254 for Evaluation of Obstructive Sleep Apnea with Long Range 3D Endoscopic FD-OCT. The principal investigator is Jun Zhang. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Obstructive sleep apnea (OSA) is a major medical problem that affects 18-20 million people in the United States. Patients with OSA suffer from fragmented sleep, chronic fatigue, daytime sleepiness, lack of concentration and memory problems with consequences including increased risk of motor vehicle accidents and the development of cardiovascular diseases with risk for ...

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    21. NinePoint Medical Receives 2014 MDEA Silver Medal for NvisionVLE Imaging System

      NinePoint Medical Receives 2014 MDEA Silver Medal for NvisionVLE Imaging System

      NinePoint Medical, Inc., an emerging leader in the development of medical devices for advanced optical imaging, today announced the company was honored with a silver medal at the 2014 Medical Design Excellence Awards (MDEA) for the company’s volumetric optical coherence tomography device, the NvisionVLE Imaging System™. NinePoint and NvisionVLE were among 54 cutting-edge products and companies across 11 medical technology product categories selected as finalists. “Our team has worked diligently over the past four years to bring the NvisionVLE Imaging System to clinicians and patients, and we are pleased that our efforts were recognized by the MDEA with this ...

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    22. Massachusetts General Hospital Receives NIH Grant for Improved Screening and Surveillance in Barrett's Patients

      Massachusetts General Hospital Receives NIH Grant for Improved Screening and Surveillance in Barrett's Patients

      Massachusetts General Hospital received a 2014 NIH grant for $464,015 for Improved Screening and Surveillance in Barrett's Patients. The principal investigator is Gary Tearney. The program began in 2003 and ends in 2015. Below is a summary of the proposed work. Barrett's esophagus (BE) is a metaplastic condition that is associated with chronic gastroesophageal reflux disease (GERD). BE is important because it can progress to esophageal adenocarcinoma, a cancer with a high mortality rate and a rapidly rising incidence. Since identification of BE with dysplasia or early cancer can lead to cure, gastroenterological societies recommend that patients ...

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    23. Case Western Reserve University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western Reserve University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western Reserve University receives a 2014 NIH grant for $373,641 for Integrated Imaging of the Form and Function of the Beating Embryonic Heart. The principal investigator is Andrew Rollins. The program began in 2006 and ends in 2017. Below is a summary of the prposed work. Congenital heart defects (CHDs) afflict 36,000 babies born in the US each year and survivors often require several surgical interventions in their shortened lifetime. Despite continuous efforts, the mechanisms leading to CHDs remain largely unclear. In part, this is because most developmental cardiology studies fail to address the influential role of ...

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