1. Optical Coherence Tomography News

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    1. Feature Of The Week 3/9/14: Deeply-Etched Optical MEMS Tunable Filter for Swept Laser Source Applications

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      Feature Of The Week 3/9/14: Deeply-Etched Optical MEMS Tunable Filter for Swept Laser Source Applications

      Ain-Shams University and Si-Ware Systems reports on a wide tuning range MEMS-based swept laser source using deep reactive ion etching on an SoI substrate. A MEMS Fabry-Pérot filter with a free-spectral range and a tuning range wider than 94 nm is presented. The measured transmission loss of the filter is between -10.2 and -13.6 dB. This filter is used to construct a swept laser source with 85 nm tuning range. These results represent the widest tuning range reported in literature for an in-plane SoI-MEMS based swept laser source using deeply-etched free-standing distributed-Bragg-reflection mirrors. The recorded tuning range ...

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      Mentions: Haitham Omran

    2. Michelson Diagnostics announces completion of data collection in Vivosight OCT trial for BCC diagnosis

      Explore Optical Coherence Tomography News Dermatology , Other Business News
      Michelson Diagnostics announces completion of data collection in Vivosight OCT trial for BCC diagnosis

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, today announces that it has completed scanning and data collection for a large 250-patient, multi-centre, prospective clinical trial of the diagnostic performance of its VivoSight™ OCT scanner in diagnosing superficial basal cell carcinoma (BCC), the most common form of skin cancer. Preliminary results from the trial are to be announced at the American Academy of Dermatology (AAD) Annual meeting in Denver, in March 2014. It is expected that full results will be published in a leading peer-reviewed journal later in the year. The study ...

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      Mentions: Michelson Diagnostics Jon Holmes Gordon Mckenzie

    3. Postdoctoral Fellow in Optical Coherence Tomography research Nanyang Technological University

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      Postdoctoral Fellow in Optical Coherence Tomography research Nanyang Technological University

      A postdoctoral fellow position is immediately available in the area of optical medical imaging at the Nanyang Technological University in the School of Electrical and Electronic Engineering. Successful candidates will join leading efforts in the development and application of new optical imaging techniques such as next-generation optical coherence tomography imaging and endoscopic microscopy for applications in disease diagnosis. Requirements Motivated candidates with expertise in optical microscopy and endoscopy, optical imaging instrumentation, signal analysis, and optical modeling are highly encouraged to apply. Previous experience with optical coherence tomography technology develop is a plus but not necessary. Salary will be commensurate with ...

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      Mentions: Nanyang Technological University Liu Linbo

    4. Postdoctoral Research Fellow for Nonlinear Optical Imaging Medical University of Vienna

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      Postdoctoral Research Fellow for Nonlinear Optical Imaging Medical University of Vienna

      The Center for Medical Physics and Biomedical Engineering at the Medical University of Vienna has an immediate opening for a Postdoctoral Research Fellow within the Drexler Lab. Prof. Wolfgang Drexler, initiator and pioneer of ultrahigh resolution optical coherence tomography ( OCT ), focuses his research interest on the development of optical imaging techniques with biological and biomedical applications. The post will involve developing a novel hybrid linear and non-linear optical microscopy imaging platform in a preclinical environment. The focus of the project is to: i) develop a novel CARS (Coherent anti-Stokes Raman Scattering) microscope and ii) perform a series of proof-of-principle investigations ...

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      Mentions: Medical University of Vienna Angelika Unterhuber

    5. Duke University Receives NIH Grant for Studying Coherent Light Scattering for Early Detection of Retinal Disease

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      Duke University Receives NIH Grant for Studying Coherent Light Scattering for Early Detection of Retinal Disease

      Duke University Received a 2014 NIH Grant for $189,624 for Studying Coherent Light Scattering for Early Detection of Retinal Disease. The principal investigator was Adam Wax. The program began in 2013 and ends in 2015. Below is a summary of the proposed work. The overall objective of this proposal is to develop a novel in vivo optical imaging system that will quantify structural biomarkers of retinal degenerative diseases. The state-of-the-art technology is measurement of the thickness of retina layers by spectral domain optical coherence tomography (SDOCT). However, while SDOCT can resolve histological layers, it lacks the resolution to measure ...

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      Mentions: National Institutes of Health Duke University Adam Wax

    6. En Face OCT Imaging of the Eye - Special Interest Group for the 2014 ARVO Annual Meeting May 2014

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      En Face OCT Imaging of the Eye - Special Interest Group for the 2014 ARVO Annual Meeting May 2014

      The Association for Research in Vision and Ophthalmology (ARVO)has approved a new Special Interest Group (SIG) for the 2014 ARVO Annual Meeting, May 4-8, 2014, in Orlando, Florida. The SIG is titled: En Face OCT imaging of the Eye – SIG, Session Number: 355. The Organizer is Andre Romano and includes the following speakers: David Huang, James Fujimoto, Philip Rosenfeld. Bruno Lumbroso, Gabriel Coscas, Min Wang, Richard Rosen. More can be found by clicking HERE .

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      Mentions: Philip J. Rosenfeld Massachusetts Institute of Technology James G. Fujimoto

    7. Feature Of The Week 3/2/14: Erasmus MC Investigates Fusion of OCT and Coronary Angiography for Accurate Assessment of the Local Blood Flow Patterns

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      Feature Of The Week 3/2/14: Erasmus MC Investigates Fusion of OCT and Coronary Angiography for Accurate Assessment of the Local Blood Flow Patterns

      Intravascular ultrasound (IVUS)-based reconstructions have been traditionally used to examine the effect of endothelial shear stress (ESS) on neointimal formation. The aim of this analysis is to compare the association between ESS and neointimal thickness (NT) in models obtained by the fusion of optical coherence tomography (OCT) and coronary angiography and in the reconstructions derived by the integration of IVUS and coronary angiography. We analyzed data from six patients implanted with an Absorb bioresorbable vascular scaffold that had biplane angiography, IVUS and OCT investigation at baseline and 6 or 12 months follow-up. The IVUS and OCT follow-up data were ...

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      Mentions: Harvard University Patrick W. Serruys Hector M. Garcia-Garcia

    8. Postdoc Job Position at Doheny Eye Institute of University of California, Los Angeles

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      Postdoc Job Position at Doheny Eye Institute of University of California, Los Angeles

      RESEARCH FIELDS: Anterior chamber image segmentation, analysis, and visualization RESEARCH LABORATORY: Doheny Image Analysis Laboratory (DIAL) at Doheny Eye Institute of University of California, Los Angeles PROJECT DESCRIPTION: We are a rapidly growing and interdisciplinary group to investigate new approaches for image segmentation, registration, visualization, and analysis in various multimodal ophthalmic images at Doheny Eye Institute, standing among the top recipients of medical research grants from the National Institutes of Health, which fund 80% of all vision research in America. This project is funded from our pharmaceutical sponsor, a well-established multi-specialty health care company. We are particularly interested in the ...

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      Mentions: National Institutes of Health UCLA Zhihong Hu

    9. Feature Of The Week 2/23/14: Texas A&M University Reports on In vivo Pump-Probe Optical Coherence Tomography Imaging in Xenopus Laevis

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      Feature Of The Week 2/23/14: Texas A&M University Reports on In vivo Pump-Probe Optical Coherence Tomography Imaging in Xenopus Laevis

      Currently, optical coherence tomography (OCT), is not capable of obtaining molecular information often crucial for identification of disease. To enable molecular imaging with OCT, we have further developed a technique that harnesses transient changes in light absorption in the sample to garner molecular information. A Fourier-domain Pump-Probe OCT (PPOCT) system utilizing a 532 nm pump and 830 nm probe has been developed for imaging hemoglobin. Methylene blue, a biological dye with well-known photophysics, was used to characterize the system before investigating the origin of the hemoglobin PPOCT signal. The first in vivo PPOCT images were recorded of the vasculature in ...

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      Mentions: Texas A&M University Brian E. Applegate Ryan L. Shelton

    10. 2014 SPIE Startup Challenge Winners Announced - First-place winner Robert McLaughlin of the University of Western Australia for OCT Needle Microscope

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      2014 SPIE Startup Challenge Winners Announced - First-place winner Robert McLaughlin of the University of Western Australia for OCT Needle Microscope

      Winners have been named in the 2014 SPIE Startup Challenge after a live competition during SPIE Photonics West in San Francisco earlier this month. Top prize went to Robert McLaughlin of the University of Western Australia, with Nicholas Durr of Massachusetts Institute of Technology taking second, and Amos Danielli of MagBiosense taking third. Jay Kumler of Jenoptik (left) and SPIE President Philip Stahl congratulate winner Robert McLaughlin of the University of Western Australia. (Photo: Joey Cobbs for SPIE) A microscope in a needle, a handheld device that prescribes corrective eyeglasses, and a device for heart attack diagnosis are winning projects ...

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      Mentions: Massachusetts Institute of Technology Duke University Adam Wax

    11. University of Washington Receives NIH Grant for Studying Non-Invasive Real-Time Label-Free 3D Imaging of Retinal Microcircuation

      Explore Optical Coherence Tomography News Ophthalmology , Funding , Velocimetry
      University of Washington Receives NIH Grant for Studying Non-Invasive Real-Time Label-Free 3D Imaging of Retinal Microcircuation

      University of Washington Received a 2014 NIH Grant for $465,750 for Studying Non-Invasive Real-Time Label-Free 3D Imaging of Retinal Microcircuation. The principal investigator is Ruikang Wang. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. Non-invasive and label-free imaging techniques for assessing retinal blood perfusion in humans - down to capillary-level resolution, are of paramount importance for improved understanding, diagnosis, treatment and management of diseases that have a vascular component in their pathogenesis, e.g., age related macular degeneration (AMD), diabetic retinopathy (DR), and open angle glaucoma (OAG). Invasive imaging techniques, e ...

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      Mentions: National Institutes of Health University of Washington Ruikang K. Wang

    12. The Medical College of Wisconsin Receives a NIH Grant for Studying Inhibition of Reflex-Induced Esophageal Adenocarcinoma by Proanthocyanidins

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      The Medical College of Wisconsin Receives a NIH Grant for Studying Inhibition of Reflex-Induced Esophageal Adenocarcinoma by Proanthocyanidins

      The Medical College of Wisconsin Received a 2014 NIH Grrant for $285,728 for Studying Inhibition of Reflex-Induced Esophageal Adenocarcinoma by Proanthocyanidins. The principal investigator is Laura Kresty. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Esophageal adenocarcinoma (EAC) rates have increased 500% over the last three decades resulting in EAC being identified as the fastest increasing of all cancer types in the US. Esophageal cancer is an extremely deadly malignancy with 5-year survival rates consistently under 20%. The precise reasons for increasing rates of EAC are an active area of ...

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      Mentions: University of Wisconsin National Institutes of Health

    13. University of Memphis Receives NIH Grant For New Techniques for Measuring Volumetric Structural changes in Glaucoma

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      University of Memphis Receives NIH Grant For New Techniques for Measuring Volumetric Structural changes in Glaucoma

      University of Memphis Received a 204 NIH Grant for $248,999 to Study New Techniques for Measuring Volumetric Structural changes in Glaucoma. The principal Investigator is Madhusudhanan Balasubramanian. The program began in 2014 and ends in 2016. Below is a summary of the proposed work. This K99/R00 application supports additional research training in computational mathematics and computer vision which will enable Dr. Madhusudhanan Balasubramanian-the applicant, to become an independent multidisciplinary investigator in computational ophthalmology. Specifically, in the K99 training phase of this grant, Dr. Balasubramanian will train at UC San Diego under the direction of Linda Zangwill PhD, an ...

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      Mentions: National Institutes of Health Linda M. Zangwill

    14. Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

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      Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

      We characterized en face features of the retinal pigment epithelium (RPE) and choroid in eyes with chronic central serous chorioretinopathy (CSCR) using a high-speed, enhanced tissue penetration, swept-source optical coherence tomography (SS-OCT) prototype. Fifteen eyes of 13 consecutive patients with the clinical diagnosis of CSCR were prospectively examined with SS-OCT. Three-dimensional 6x6mm macular cube raster scans were obtained with SS-OCT operating at 1050nm wavelength and 100,000 A-lines/sec with 6µm axial resolution. Segmentation of the RPE generated a reference surface; en face SS-OCT images of the RPE and choroid were extracted at varying depths every 3.5 µm ...

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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Jay S. Duker

    15. Heidelberg Spectralis OCT Eye Examinations in Space

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      Heidelberg Spectralis OCT Eye Examinations in Space

      Since its arrival at the International Space Station (ISS) on June 15 th , 2013, Heidelberg Engineering’s Spectralis OCT device is being used regularly for eye examinations of ISS crewmembers. First on-orbit tests of the instrument were conducted successfully on June 21 of last year. The first ever OCT examination in space was performed with a commercial SPECTRALIS OCT device on board ISS on October 16, 2013. Since then, ISS crewmembers are being examined in 1- to 2-week intervals. The examinations are part of NASA’s Ocular Health Study, which seeks to understand ocular changes in astronauts during long-term space ...

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      Mentions: Heidelberg Engineering Heidelberg Spectralis

    16. Michelson Diagnostics to launch enhanced software for VivoSight OCT scanner

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      Michelson Diagnostics to launch enhanced software for VivoSight OCT scanner

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, today announces the launch of its upgraded VivoSight OCT scanner with a new software technology that provides additional features for dermatologists to investigate skin lesions such as non-melanoma skin cancer. The VivoSight OCT scanner enables the dermatologist to see vertical cross-sectional images of sub-surface skin tissue to depths of 1-1.5 mm in high definition, providing the clinician with important information about the type, depth and lateral spread of the skin lesion that is not possible to determine from its surface visual appearance. Our ...

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      Mentions: Michelson Diagnostics Jon Holmes Michelson Diagnostics Vivosight

    17. Feature Of The Week 2/9/14: Incidences, Predictors, and Clinical Outcomes of Acute and Late Stent Malapposition Detected by Optical Coherence Tomography After Drug-Eluting Stent Implantation

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      Feature Of The Week 2/9/14: Incidences, Predictors, and Clinical Outcomes of Acute and Late Stent Malapposition Detected by Optical Coherence Tomography After Drug-Eluting Stent Implantation

      Background—We investigated the incidences, predictors, and clinical outcomes of acute and late stent malapposition detected by optical coherence tomography (OCT) after drug-eluting stent implantation. Methods and Results—We analyzed the OCT images from 351 patients with 356 lesions who received poststent and follow-up OCT examinations. Acute stent malapposition was observed in 62% of lesions. Approximately half of the acute stent malappositions were located within the edges of the stents. Severe diameter stenosis, calcified lesions, and long stents were independent predictors of acute stent malapposition. Follow-up OCT examinations were performed 175±60 days after drug-eluting stent implantation. Thirty-one percent of ...

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      Mentions: Yonsei University Myeong-Ki Hong

    18. The Role of Novel Biophotonic Technique in Characterization of the Newly Developed Nanotechnology based Dental Composites (Thesis)

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      The Role of Novel Biophotonic Technique in Characterization of the Newly Developed Nanotechnology based Dental Composites (Thesis)

      [Background and Objective]: Polymerization shrinkage and the associated contraction stresses are the major shortcoming of dental composites in dentistry, which may affect the bonding performance and result in gap formation at the tooth-restoration interface. Non-destructive assessment and monitoring of these defects are critically important. The aim of this study is to assess the toothrestoration interface and composite adaptation using swept source optical coherence tomography (SS-OCT) in combination of microtensile bond strength (MTBS) and to confirm the findings with confocal laser scanning microscope (CLSM) and scanning electron microscopy (SEM). [Materials and Methods]: Standard round class-I cavities were prepared in human premolar ...

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      Mentions: Turki Bakhsh

    19. Axsun Technologies Announces Volume Purchase Order for Swept Laser Engines from Michelson Diagnostics Ltd.

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      Axsun Technologies Announces Volume Purchase Order for Swept Laser Engines from Michelson Diagnostics Ltd.

      Axsun Technologies, Inc., a wholly-owned subsidiary of Volcano Corporation ( VOLC ) and a leading developer and manufacturer of advanced photonic components and subsystems, has received a volume purchase order for Swept Laser OCT Engines from Michelson Diagnostics Ltd. The Axsun Swept Laser OCT Engine will power the new Michelson Diagnostics' Vivosight Multi-Beam OCT system. The Vivosight Multi-Beam OCT system is the first OCT scanner to receive FDA 510(k) clearance for imaging skin in high definition, revealing subsurface tissue structure at unprecedented detail. "Axsun's Swept Laser OCT Engines are ideally suited for real-time OCT imaging in many imaging applications," said ...

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      Mentions: Michelson Diagnostics Axsun Technologies Jon Holmes

    20. Feature Of The Week 2/2/14: Tsinghua University.Demonstrates Linear-in-Wavenumber Swept Laser with an Acousto-Optic Deflector for OCT

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      Feature Of The Week 2/2/14: Tsinghua University.Demonstrates Linear-in-Wavenumber Swept Laser with an Acousto-Optic Deflector for OCT

      Compared to the conventional time domain OCT, the frequency domain (FD) detection techniques enable a dramatic increase in imaging speed. Spectrometer-based FD-OCT (SD-OCT) systems are already widely used, especially for ophthalmic application in the 800 nm wavelength range. Alternatively, the application of FD-OCT systems based on a rapidly swept, narrowband light source, i.e. swept source OCT (SS-OCT) offers the additional advantages of dual balance detection, potentially longer ranging depth and higher imaging speeds. However, a general disadvantage of most FD-OCT systems is the requirement to resample and recalibrate the detected OCT interference fringe prior to fast Fourier transformation, in ...

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      Mentions: Tsinghua University Ping Xue Jing-gao Zheng

    21. Share your OCT Thesis on OCT News

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      Share your OCT Thesis on OCT News

      OCT News is seeking links to bachelors, masters, and PhD theses in the area of "Optical Coherence Tomography". Traditionally student theses contain a great wealth of information but are rarely accessible to the OCT community. If you or someone you know wrote an OCT thesis and would like to share it with the community please submit a link or PDF using the "Contact OCT News" tab in the main menu bar or the feedback link in the footer and we will include it here: Student Theses. Thesis will only be included if the link is free of charge to users.

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    22. Axsun’s New Lead-Free Tunable Laser Platform Meets Requirements of ROHS2 Directive

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      Axsun’s New Lead-Free Tunable Laser Platform Meets Requirements of ROHS2 Directive

      Axsun Technologies Inc., a wholly-owned subsidiary of Volcano Corporation and a leading developer and manufacturer of advanced photonic components and subsystems, has announced the Qualification of their new Lead-Free Tunable Laser packaging platform. Axsun's new Lead-Free platform provides the same performance and reliability as previous generations and meets the requirements of the Reduction of Hazardous Substances (ROHS) Directive 2011/65/EU (also known as ROHS2). This new directive eliminates exemptions for several product categories, including Medical Devices that were present in the 2002 Directive. Axsun will begin sampling new Lead-Free Engines in May 2014. "Axsun's Swept Laser OCT ...

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      Mentions: Axsun Technologies Volcano Corporation

    23. Presentation by Fujikura on Optical Components for OCT

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      Presentation by Fujikura on Optical Components for OCT

      Fujikura is a global company with 130 year history and over 52,000 employees with products in Automotive, Electronics, Power, and Telecommunications business segments. Fujikura Telecommunications segment has a long history and is a leading supplier of optical components. For a Fujikura presenation on their Optical Components for OCT click HERE . Please contact Shingo Ishii at " medical@jp.fujikkura.com " for product information.

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      Mentions: Fujikura Ltd.

    24. Wasatch Photonics launches Cobra OCT spectrometer with USB 3.0 interface

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      Wasatch Photonics launches Cobra OCT spectrometer with USB 3.0 interface

      WEST LAFAYETTE, Ind., LOGAN, Utah and DURHAM, N.C. - Professionals using optical coherence tomography (OCT) for imaging applications in areas like ophthalmology, dermatology and material inspection may benefit from a new spectrometer to be demonstrated in San Francisco from Feb. 1-6. Wasatch Photonics Inc. has launched the Cobra OCT spectrometer, which provides a USB 3.0 interface. Nishant Mohan, director of product management, said the interface improves accessibility and reduces expense for OCT technology. "Cobra is the first OCT spectrometer that provides the USB 3.0 interface, to our knowledge. This will allow users to do away with expensive camera ...

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      Mentions: Wasatch Photonics
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