1. Optical Coherence Tomography News

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    1. First Human Clinical Images Available with OCTIS™ Thanks to Tomophase Corporation and the Thoraxklinik, University of Heidelberg

      First Human Clinical Images Available with OCTIS™ Thanks to Tomophase Corporation and the Thoraxklinik, University of Heidelberg

      Tomophase Corporation, a leading developer of minimally invasive optical coherence tomography (OCT) tissue imaging devices, announced today that the Thoraxklinik at the University of Heidelberg, Germany has taken the first OCTIS images in clinical patients with the Tomophase OCT Imaging System (OCTIS™). On Tuesday, May 7th Tomophase OCTIS was used for the first time to examine the airways of a patient undergoing bronchoscopy at the Thoraxklinik. The following day another patient was examined. (Courtesy of the Thoraxklinik, University of Heidelberg) The clinicians were quite intrigued of the results and plan to do further work in due course. The Tomophase OCTIS ...

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    2. Feature Of The Week 5/19/13: Using Optical Coherence Tomography For Anti-Spoof Fingerprint Detection

      Feature Of The Week 5/19/13: Using Optical Coherence Tomography For Anti-Spoof Fingerprint Detection

      Fingerprint biometrics, including automated fingerprint identification systems (AFIS), currently occupy two-thirds of the biometric market and are expected to remain the dominant player in this area. The technology can be integrated into small, compact devices and the instruments are relatively fast. However, the overall success of using fingerprints for identification and verification purposes greatly depends upon the quality of the fingerprints initially enrolled. For example, fingerprints captured from older people are significantly lower quality than those from younger people due primarily to ridge-wearing and difficulty of interacting effectively with conventional fingerprint scanners. The ramification is that the problem of obtaining ...

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    3. First International En Face OCT Congress in Rome December 14 2013

      First International En Face OCT Congress in Rome December 14 2013

      The First international meeting on “en face”OCT in Rome Saturday December 14. Co-organizers are Bruno Lumbroso (Rome) Philip Rosenfeld (Miami) and Gabriel Coscas (Paris). Duration one day. We will discuss next developments of clinical “en face” OCT and clinical applications of this technique. For more information click HERE . Meeting Site ( www.symposiacongressi.eu and secretariat anna.porro@symposiacongressi.eu )).

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    4. St. Jude Medical Announces European Approval of 3-D Vessel Reconstruction Technology to Aid Physicians in Stent Placement

      St. Jude Medical Announces European Approval of 3-D Vessel Reconstruction Technology to Aid Physicians in Stent Placement

      St. Jude Press Release - St. Jude Medical, Inc. (NYSE:STJ), a global medical device company, today announced CE Mark approval of its ILUMIEN™ OPTIS™ PCI Optimization System™, a new technology designed to provide physicians with a comprehensive disease assessment tool for treating patients with coronary artery disease (CAD). The system will be on display for the first time in Europe during EuroPCR. 3-D image of a stent inside a coronary artery taken using the ILUMIEN(TM) OPTIS(TM) (Photo: St. Jude Medical, Inc.) The ILUMIEN OPTIS system provides enhancements to the ILUMIEN ™ system, including first-of-its-kind stent planning software tools to ...

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    5. NinePoint Medical Announces U.S. Commercial Availability of the NvisionVLE™ Imaging System

      NinePoint Medical Announces U.S. Commercial Availability of the NvisionVLE™ Imaging System

      NinePoint Press Release - NinePoint Medical, Inc., an emerging leader in the development of medical devices for advanced optical imaging, today announced the commercial launch of its proprietary NvisionVLE ™ Imaging System in the United States. In addition, NinePoint today announced the launch of its newly redesigned website, www.ninepointmedical.com . In December 2011, the NvisionVLE Imaging System received 510(k) clearance from the U.S. Food and Drug Administration for use as an imaging tool in the evaluation of human tissue microstructure by providing two-dimensional, cross sectional, real-time depth visualization. Last month, NinePoint received 510(k) clearance to expand the System ...

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    6. NinePoint Medical to Present NvisionVLE Clinical Data at Digestive Disease Week 2013

      NinePoint Medical to Present NvisionVLE Clinical Data at Digestive Disease Week 2013

      NinePoint Medical Press Release - NinePoint Medical, Inc., an emerging leader in the development of medical devices for in vivo imaging, today announced that new clinical data on its proprietary NvisionVLE ™ Imaging System will be featured in five poster presentations during Digestive Disease Week (DDW) taking place May 18-21, 2013, in Orlando, Fla. In addition, researchers from Massachusetts General Hospital (MGH) will highlight the core imaging technology of NvisionVLE, as well as a follow-on confocal endomicroscopy system, in two oral and two poster presentations. NinePoint licensed the imaging technology from MGH in 2010 as part of the largest intellectual property agreement ...

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    7. Feature Of The Week 5/12/13: University of Illinois at Urbana-Champaign Reports on Real-Time In Vivo Computed Optical Interferometric Tomography

      Feature Of The Week 5/12/13: University of Illinois at Urbana-Champaign Reports on Real-Time In Vivo Computed Optical Interferometric Tomography

      Real-time, high-resolution tomography over an extended field-of-view in scattering tissues remains an elusive goal for biomedical imaging. The apparent trade-off between the depth-of-field and lateral resolution in optical imaging degrades the image resolution outside the confocal region in OCT. Although a number of approaches have been utilized to overcome these limitations, many of these techniques are plagued by either high computational complexity or complicated optical setups. ISAM is a computational technique that can yield spatially invariant transverse resolution by resampling the Fourier space of the data. However, a full 3D ISAM reconstruction requires extensive manipulation of volumetric datasets, imposing significant ...

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    8. Case Western Reserve University Receives NIH Grant for Investigating Optical Pacing of the Embryonic Heart

      Case Western Reserve University Receives NIH Grant for Investigating Optical Pacing of the Embryonic Heart

      Case Western Reserve University Received a 2013 NIH Grant for $176,625 for Investigating Optical Pacing of the Embryonic Heart. The principal investigator is Michael Jenkins. The program started in 2012 and ends in 2014. Below is a summary of the proposed work. Our long-term objective is to determine the influence biophysical forces have on heart development and how alterations of these forces early in development can lead to congenital heart defects (CHDs). CHDs are extremely prevalent affecting almost 36,000 newborns in the US each year, or 9 out of 1,000 live births. In order to tease apart ...

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    9. University of Arizona Receives NIH Grant for Diagnosis of Ovarian Cancer by Confocal Microendoscopy.

      University of Arizona Receives NIH Grant for Diagnosis of Ovarian Cancer by Confocal Microendoscopy.

      University of Arizona Received a 2013 NIH Grant for $65,063 for Diagnosis of Ovarian Cancer by Confocal Microendoscopy. The principal investigator is Arthur Gmitro. The program started in 2005 and ends in 2014. Below is a summary of the proposed work. The objective of this research is to further develop and clinically validate a real-time multispectral confocal microendoscope for in vivo diagnosis of ovarian cancer. The confocal microendoscope is a new type of instrument for visualizing tissue at the cellular level and has shown great promise for performing optical biopsy. Confocal microendoscopy has the potential to provide a physician ...

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    10. Mirrorcle Technologies announces availability of 4.2mm diameter MEMS 2-Axis mirrors

      Mirrorcle Technologies announces availability of 4.2mm diameter MEMS 2-Axis mirrors

      Mirrorcle Technologies Press Release - Mirrorcle Technologies announces availability of 4.2mm diameter MEMS mirrors Mirrorcle Technologies, Inc (MTI), the California-based manufacturer of patented, gimbal-less MEMS micromirror devices, today announces the availability of a larger category of mirrors. Until now, the company has been offering integrated mirror devices ranging from 0.8mm to 1.7mm in diameter, and bonded mirrors from 0.8mm to 3.6mm in diameter. Mirrorcle’s bonded MEMS mirror devices are modular in design, consisting of an actuator ‘engine’ and a mirror of customer-selected size. With a variety of different MEMS actuators, a selection of aluminum or ...

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    11. Feature Of The Week 5/5/13: University of Maryland Reports Interesting Results on OCT Needle Probe Used In Conjunction with Magnetic Resonance Imaging for Precision Surgical Procedures

      Feature Of The Week 5/5/13: University of Maryland Reports Interesting Results on OCT Needle Probe Used In Conjunction with Magnetic Resonance Imaging for Precision Surgical Procedures

      We develop a novel platform based on a tele-operated robot to perform high-resolution optical coherence tomography (OCT) imaging under continuous large field-of-view magnetic resonance imaging (MRI) guidance. Intra-operative MRI (iMRI) is a promising guidance tool for high-precision surgery, but it may not have sufficient resolution or contrast to visualize certain small targets. To address these limitations, we develop an MRI-compatible OCT needle probe, which is capable of providing microscale tissue architecture in conjunction with macroscale MRI tissue morphology in real time. Coregistered MRI/OCT images on ex vivo chicken breast and human brain tissues demonstrate that the complementary imaging scales ...

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    12. Symposium on Dental OCT June 20th 2013 in Tokyo, Japan.

      Symposium on Dental OCT June 20th 2013 in Tokyo, Japan.

      Tokyo Medial and Dental University will hold a special symposium in Tokyo on June 20 (Thu) on the development and application of Optical Coherence Tomography in Dentistry. The symposium is sponsored by Tokyo Medical and Dental University, and some of the pioneers of dental OCT from Japan and US will talk about the latest developments in the field (see the list of speakers at http://www.tmdu.net/oct/ ) . All interested individuals including students, researchers and company representatives are invited to attend this event. Registration fees will be waived for those who pre-register by June 3 online at http://www ...

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    13. Bioptigen introduces 1 µm resolution SD-OCT imaging system in collaboration with NKT Photonics supercontinuum white light laser source at ARVO conference in Seattle

      Bioptigen introduces 1 µm resolution SD-OCT imaging system in collaboration with NKT Photonics supercontinuum white light laser source at ARVO conference in Seattle

      Bioptigen/NKT Press Release - Bioptigen Inc. has introduced 1 um axial resolution imaging to its line of Envisu TM spectral domain OCT systems. The company has now integrated NKT Photonics SuperK supercontinuum laser with Bioptigen’s new 300 nm spectrometer to achieve a breakthrough in ophthalmic imaging for preclinical research. “The progression to 1 um extreme resolution imaging is an exciting advancement for our Envisu R-Class research product line”, said Dr. Eric Buckland, CEO of Bioptigen. “The importance of this innovation is that it offers researchers true cellular-level in vivo optical histology. This Extreme High Resolution (XHR) capability is unlocked ...

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    14. Associate Professor/Professor Positions (Biomedical Optics) at Chinese Academy of Sciences: Shenzhen, China

      Associate Professor/Professor Positions (Biomedical Optics) at Chinese Academy of Sciences: Shenzhen, China

      Two faculty positions at the rank of either Associate Professor or Professor level are available at the Institute of Biomedical and Health Engineering ( IBHE ) of the Shenzhen Institutes of Advanced Technology ( SIAT ), the Chinese Academy of Sciences. Candidates will have a Ph.D. degree in Biomedical Engineering, Electrical Engineering, Physics, or Chemistry (with experience in optical imaging), as well as a track-record of high-quality publications and exceptional potential to become independently-funded principal investigators. Preferred research areas include, but are not limited to: optical coherence tomography, fluorescence molecular tomography, super resolution microscopy, advanced optical endomicroscopy, and nano-materials for optical imaging. SIAT ...

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    15. Full-Time PhD Scholarship in Advanced Optical Imaging and Nanomaterial Nottingham Trent University, School of Science & Technology

      Full-Time PhD Scholarship in Advanced Optical Imaging and Nanomaterial Nottingham Trent University, School of Science & Technology

      Advanced non-invasive optical imaging techniques such as optical coherence tomography (OCT) and hyperspectral imaging have found increasing applications in a wide range of disciplines from biomedical science to archaeology. A variety of state-of-the-art OCT and spectral imaging instruments have been developed in our group for specific material imaging applications. This project will develop methods for non-invasive material identification, dynamic imaging of novel nanomaterial (as both functional and contrast agents) in collaboration with colleagues in chemistry. One of the main aspects of the applications is on imaging of cave paintings along the Silk Road at a UNESCO world heritage site for ...

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    16. University of California at Irvine Receives NIH Grant for Evaluation of Obstructive Sleep Apnea with Long Range 3D Endoscopic FD-OCT

      University of California at Irvine Receives NIH Grant for Evaluation of Obstructive Sleep Apnea with Long Range 3D Endoscopic FD-OCT

      University of California at Irvine Received a 2013 NIH Grant for $123,249 for Evaluation of Obstructive Sleep Apnea with Long Range 3D Endoscopic FD-OCT. The principal investigator is Jun Zhang. The program started in 2011 and ends in 2016. Below is a summary of the proposed work. There are approximately 20-40 million people in the United States with sleep apnea. The majority of them are undiagnosed and untreated at this time. Sleep apnea can lead to severe health complications including hypertension, heart failure, memory impairment, motor vehicle and work accidents, decreased work productivity, and increased risk of death. The ...

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    17. University of Pittsburgh Receives NIH Grant for Microsurgical In-Situ Image Guidance With Optical Coherence Tomography

      University of Pittsburgh Receives NIH Grant for Microsurgical In-Situ Image Guidance With Optical Coherence Tomography

      University of Pittsburgh Receives 2013 NIH Grant for $501,440 Microsurgical In-Situ Image Guidance With Optical Coherence Tomography. The principal investigator is George Stetten. The program started in 2011 and ends in 2015. Below is a summary of the proposed work. Over the past eight years of continuous funding by NIH, our laboratory has developed the concept of in-situ image guidance, which permits a real-time tomographic scan to be displayed as a virtual image within the patient, superimposed on the clinician's direct view of hands, tools, and target. One result has been a new ultrasound device, the Sonic Flashlight ...

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    18. CBORT 2013 OCT Symposium July 29th at Harvard Medical School Cambridge MA, USA

      CBORT 2013 OCT Symposium July 29th at Harvard Medical School Cambridge MA, USA

      OCT2013 – the first international symposium hosted by the Center for Biomedical OCT Research and Translation at Harvard Medical School and Massachusetts General Hospital, will focus on the latest and greatest technical capabilities of OCT, provide an overview of the commercially available OCT systems, discuss advancements in numerous clinical application areas, and introduce emerging preclinical optical imaging techniques. The unique emphasis of technology and clinical utility presented in the symposium will bring together an interdisciplinary group of expert clinicians, engineers, physicists, biologists, businesspersons, and trainees from around the world to foster the realization of OCT technology and implementation in the clinic ...

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    19. Feature Of The Week 4/28/13: King Abdullah University of Science and Technology Investigates Online Monitoring of Printed Electronics by SD-OCT

      Feature Of The Week 4/28/13: King Abdullah University of Science and Technology Investigates Online Monitoring of Printed Electronics by SD-OCT

      Printing technology is now being utilized to fabricate electronics and other active and passive devices and structures. Rotary printing techniques such as rotogravure, rotary screen, and flexography have been advantageous due to their ability to integrate with other rotary techniques to form what we refer to as Roll-to-Roll (R2R) process. In a R2R process, a roll of the base material (referred to as substrate) is unwined, functional materials printed on top of the substrate to form the needed structures or device, dried and rewined back to roll, or cut into individual devices. Most of current characterization of printed devices is ...

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    20. Haag-Streit USA and Optovue Team Up to Introduce Octopus/Optovue Bundle

      Haag-Streit USA and Optovue Team Up to Introduce Octopus/Optovue Bundle

      Hagg-Streit/Optovue Press Release - Haag-Streit USA and Optovue have joined forces to bundle Haag-Streit's Octopus perimeter with Optovue's Optical Coherence Tomography (OCT) technology. The combined Octopus/OCT offering will be distributed by Optovue in the United States . "Haag-Streit is happy to partner with Optovue for its leadership in OCT technology and outstanding customer service. Our bundled technologies will create an advanced package that will provide a superior diagnostic tool to the ophthalmic industry," said Ernest Cavin , president and chief executive officer of Haag-Streit USA . "The OCT technology provided by the RTVue and iVue combined with the functional testing ...

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      Mentions: Optovue Jay Wei FDA
    21. NinePoint Medical Receives Additional FDA 510(k) Clearance for NvisionVLE Imaging System

      NinePoint Medical Receives Additional FDA 510(k) Clearance for NvisionVLE Imaging System

      NinePoint Medical Press Release - NinePoint Medical, Inc. , an emerging leader in the development of medical devices for in vivo imaging, today announced that it has received an additional 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its NvisionVLE ™ Imaging System, expanding the system’s indication to include imaging of esophageal tissue microstructure. In January 2012, the company announced 510(k) clearance from the FDA to market its NvisionVLE Imaging System for use as an imaging tool in the evaluation of human tissue microstructure by providing two-dimensional, cross sectional, real-time depth visualization. “The NvisionVLE Imaging System ...

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    22. Duke University Receives NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health

      Duke University Receives NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health

      Duke University Received a 2013 NIH Grant for $410,399 for Novel Determination of Microbicide PK in Women's Reproductive Health. The principal investigator is David Katz. The program started in 2012 and ends in 2016. Below is a summary of the proposed work. Vaginal microbicides offer much promise to prevent sexual transmission of HIV. The pharmacokinetics (PK) of a product (active pharmaceutical ingredient + dosage form) is central to prophylactic functionality (PD). But our ability to measure and predict microbicide PK is currently limited. Further, microbicide PD depends on how product + dosage regimen accommodate a range of conditions of the ...

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    23. Feature Of The Week 4/21/13: University of Toronto Investigates Analysis of OCT Speckle to Differentiate Tissue Disease State

      Feature Of The Week 4/21/13: University of Toronto Investigates Analysis of OCT Speckle to Differentiate Tissue Disease State

      Optical coherence tomography is playing an increasingly important role in the differentiation between normal and diseased tissue states in situ. While OCT’s resolution is typically on the micrometer scale and is generally insufficient for direct visualization of cellular organelles and cellular level changes, as these are submicrometer in size. Recently researchers at the University of Toronto, Sunnybrook Health Sciences Center, University Health Network, and National Research Council Canada published some interesting results investigating speckle which is highly correlated with the underlying scatterers’ average properties, such as size, shape, and distribution. Such an approach may give important information on sub-micrometer ...

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    24. Terumo Commences Sales of OFDI Intravascular Imaging System in Japan "LUNAWAVE" OFDI System and "FastView" OFDI Imaging Catheter

      Terumo Commences Sales of OFDI Intravascular Imaging System in Japan "LUNAWAVE" OFDI System and "FastView" OFDI Imaging Catheter

      Terumo Corporation Press Release - Terumo Corporation announced that from this April it has begun a Japanese sales launch of its "LUNAWAVE™" OFDI system, a light based intravascular imaging system, as well as its "FastView™" OFDI imaging catheter. Terumo aims to achieve the revenue of 1.7 billion yen ($17.3M) for both products in fiscal year 2013. OFDI (Optical Frequency Domain Imaging) employs light applied to the vessel wall from the tip of a catheter, and constructs an intravascular cross-sectional image through a new technology that analyzes the back scattered light from the vessel walls. It is mainly utilized in ...

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