1. Optical Coherence Tomography News

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    1. Case Western Reserve University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western Reserve University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western Reserve University Receives a 2016 NIH Grant for $356,784 for Integrated Imaging of the Form and Function of the Beating Embryonic Heart. The principal investigator is Andrew Rollins. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Congenital heart defects (CHDs) afflict 36,000 babies born in the US each year and survivors often require several surgical interventions in their shortened lifetime. Despite continuous efforts, the mechanisms leading to CHDs remain largely unclear. In part, this is because most developmental cardiology studies fail to address the influential role of ...

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    2. Research Associate Position in OCT at the University of Maryland

      Research Associate Position in OCT at the University of Maryland

      Position description: A Postdoctoral Research Associate position is available at the University of Maryland, College Park. Research projects include intraoperative imaging of transplant kidney viability using OCT in collaboration with Georgetown University Medical Center, and development of automatic image processing algorithm to predict organ viability. Required expertise: Ph.D. in physics, electrical engineering, optical engineering, or biomedical/bioengineering. Hand-on experience on optical and electronic instrumentation and strong programming skills (Matlab, Labview, and C++). Prior research expertise on OCT and image processing. Application: Interested candidates should submit Curriculum vitae with a list of contact information of 3 references by email to ...

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    3. Postdoctoral Fellow Position at the Advanced Ophthalmic Imaging Laboratory at Indian Universitiy

      Postdoctoral Fellow Position at the Advanced Ophthalmic Imaging Laboratory at Indian Universitiy

      The Advanced Ophthalmic Imaging Laboratory at Indiana University is looking to fill a postdoctoral fellow or research associateposition. The successful candidate will join a team of scientists and engineers that are developing the next-generation adaptive optics–optical coherence tomography (AO-OCT) system for studying structure and function of the living human retina at the cellular level. The system will open up exciting new directions to study both normal and pathological vision. The laboratory ( www.opt.indiana.edu/dtmiller/Index.aspx ) is part of the Indiana University Visual Optics Group, an active and well-funded community of vision scientists and engineers working in ...

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    4. Coin-Sized Scanner to Target Blindness

      Coin-Sized Scanner to Target Blindness

      A European group of scientists are working on the development of a breakthrough, compact, cost-effective retinal scanner that will play a key role in targeting the early diagnosis of retinal diseases that are worldwide leading causes of blindness. Funded by the Photonics PPP platform, OCTChip is set to revolutionise diagnosis of retinal diseases and prevent millions of cases of blindness. Diabetic Retinopathy accounts for the leading cause of blindness, with 200 million cases worldwide, and 60 million affected Europeans. With an ageing population, higher life expectancies and rising levels of diabetes, the number of cases preventable blindness are increasing. The ...

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    5. Massachusetts General Hospital Receives NIH Grant for Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      Massachusetts General Hospital Receives NIH Grant for Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      Massachusetts General Hospital Receives a 2016 NIH Grant for $742,986 for Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function. The principal investigator is David Sosnovik. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. Pressure overload of the left and right ventricles initially leads to adaptive hypertrophy. This, however, is frequently followed by maladaptive hypertrophy, heart failure and death. We hypothesize here that changes in 3D myocardial fiber architecture play a significant role in the deleterious transition from adaptive to maladaptive hypertrophy and heart failure. We further hypothesize that ...

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    6. State University of New York Stony Brook Received NIH Grant for Optical Platform to Image Neuronal And Visual Effects of Cocaine In Awake Rodents

      State University of New York Stony Brook Received NIH Grant for Optical Platform to Image Neuronal And Visual Effects of Cocaine In Awake Rodents

      State University of New York Stony Brook Received a 2016 NIH Grant for $195,071 for Optical Platform to Image Neuronal And Visual Effects of Cocaine In Awake Rodents. The principal investigator is Congwu Du. The program began in 2016 and ends in 2018. Below is a summary of the propose work. The medial prefrontal cortex (mPFC) plays a critical role in cocaine addiction. The mechanism underlying mPFC dysfunction in cocaine abusers are not well understood and could reflect disruption of cerebral blood flow (cocaine’s vascular effects) and/or disruption of dopaminergic modulation of the prefrontal cortex (cocaine’s ...

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    7. Yale University Receives NIH Grant for Quantitative Optical Imaging of Cilia-Driven Fluid Flow

      Yale University Receives NIH Grant for Quantitative Optical Imaging of Cilia-Driven Fluid Flow

      Yale University Receives a 2016 NIH Grant for $416,250 for Quantitative Optical Imaging of Cilia-Driven Fluid Flow. The principal investigator is Michael Choma. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Respiratory diseases are major causes of pediatric morbidity and mortality. These diseases are incompletely understood, which is a barrier to improving clinical care. Therefore, new mechanisms of disease need to be discovered. Optical imaging (e.g. optical coherence tomography [OCT]) will enable these discoveries since traditional imaging (e.g. x-ray, CT, MRI) cannot visualize structures smaller than ~1 mm ...

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    8. Johns Hopkins University Receives NIH Grant for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives NIH Grant for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives a 2016 NIH Grant for $746,856 for Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo. The principal investigator is Robert Brown. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. This Biomedical Research Partnership (BRP) proposal involves a partnership among a biomedical engineering team, a pulmonary physiology team, and a clinical pulmonary medicine team. This research program will incorporate state of the art optical engineering, advanced in vivo physiologic evaluation, and direct application to human obstructive lung diseases (OLD). Optical coherence tomography (OCT) is ...

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    9. UIUC Receives NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      UIUC Receives  NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      University of Illionois at Urbana-Champaign Receives a 2016 NIH Grant for $490,333 for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins. The principal investiagator is Stephen Boppart. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving surgeries or lumpectomies are routinely performed. Currently, the surgeon is unable to visualize the microscopic structure at the margin, and conventionally relies on post-operative histological assessment of surgical margins to ...

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    10. OPTOVUE ANNOUNCES NEW ANGIOVUE RETINA IMAGING SYSTEM COMMERCIAL AVAILABILITY

      OPTOVUE ANNOUNCES NEW ANGIOVUE RETINA IMAGING SYSTEM COMMERCIAL AVAILABILITY

      Optovue, the global leader in the development of optical coherence tomography ( OCT ) and OCT angiography ( OCTA ), today announced immediate availability of AngioVue™ Retina , a proprietary imaging system that provides retina specialists with a non-invasive, dyeless way to quickly visualize blood flow in the retina, the light sensitive portion in the back of the eye. AngioVue Retina is configured with essential OCTA and OCT features designed specifically for retinal practices to allow adoption of OCT and OCTA into the clinical workflow with minimal disruption. “By adding AngioVue Retina to our product portfolio, we are able to help retinal physicians acquire OCTA ...

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      Mentions: Optovue FDA
    11. Postdoctoral research position for Biomedical/Optics Engineer Scientist at Harvard Medical School and Wellman Center

      Postdoctoral research position for Biomedical/Optics Engineer Scientist at Harvard Medical School and Wellman Center

      The ear is a remarkable example of a biomechanical system. The goal of the OtoBiomechanics Group in the Otolaryngology Department at the Harvard Medical School is to use the OCT imaging modality combined with computational models and physiological measurements to understand the high sensitivity, high frequency selectivity and wide bandwidth of mammalian hearing. The project is well funded by grants from the NIH. Applications are invited for a post-doctoral research fellowship position to develop and build a state-of-the-art micro optical coherence topography (u-OCT) system to study cochlear and middle ear imaging and vibrometry in the laboratories of Profs. Sunil Puria ...

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    12. Post-Doc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis

      Post-Doc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Retinal Imaging Laboratory at University of California, Davis

      Applications are invited for post-doctoral research associate position in the UC Davis EyePod Small Animal Imaging Laboratory in the Department of Cell Biology and Human Anatomy at the UC Davis Main Campus. The goal of our research is to develop and translate the next generation in vivo cellular resolution multimodal retinal imaging instruments and data analysis tools and to apply them to disease mechanisms and therapeutic interventions that can be investigated in the eye. The ideal candidate will have strong skills in some combination of retinal/microscopic imaging modalities, including but not limited to adaptive optics (AO), OCT, SLO, multispectral ...

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    13. Perimeter Medical Imaging Receives FDA Clearance for OTISTM Optical Tissue Imaging System

      Perimeter Medical Imaging Receives FDA Clearance for OTISTM Optical Tissue Imaging System

      Perimeter Medical Imaging, Inc., an innovative medical imaging company whose mission is to revolutionize tissue removal surgery for surgeons and patients, today announced receipt of U.S. Food and Drug Administration (FDA) 510(k) clearance for its OTIS TM 1.0 Optical Coherence Tomography System. The OTIS™ provides high-resolution, real-time imaging of the periphery of excised tissue, enabling clinicians to visualize sub-surface structures up to 2 mm below the surface. These sub-surface structures would otherwise not be evident until days – and often weeks – later when conventional histology slides are available for review. Dr. Ted James, Medical Director of Skin & Soft ...

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    14. Postdoctoral Research Fellowship in Clinical Applications of Image Processing at Duke University

      Postdoctoral Research Fellowship in Clinical Applications of Image Processing at Duke University

      Immediate opening at Duke University Biomedical Engineering Department for a Postdoctoral Research Associate interested in interdisciplinary applications of image analysis and computer vision with emphasis on applications in Optical Coherence Tomography (OCT) and adaptive optics (AO) imaging. Postdoc will be supervised by Prof. Sina Farsiu ( http://people.duke.edu/~sf59/ ) in collaboration with Prof. Joseph A. Izatt ( http://bme.duke.edu/faculty/joseph-izatt ) and other senior professors from Duke University School of Medicine. The candidate must have a demonstrated strong background in image processing as evidenced by publication of papers in high-impact peer-reviewed journals. Programming skill in MATLAB is required ...

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    15. Postdoctoral Research Fellowship in ophthalmic adaptive optics optical coherence tomography imaging at Duke University

      Postdoctoral Research Fellowship in ophthalmic adaptive optics optical coherence tomography imaging at Duke University

      Immediate opening at Duke University Biomedical Engineering Department for a Postdoctoral Research Associate interested in development of novel fast and high-resolution ophthalmic adaptive optics (AO) and Optical Coherence Tomography (OCT) imaging systems. Postdoc will be supervised by Prof. Joseph A. Izatt ( http://bme.duke.edu/faculty/joseph-izatt ) in collaboration with Prof. Sina Farsiu ( http://people.duke.edu/~sf59/ ). Multiple previous PhD students and postdocs from this team are now faculty members in top universities around the world. Requirement: PhD in EE, BME, or CS. The candidate must have a demonstrated strong background in optical design and photonics imaging as evidenced ...

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    16. Oregon Health and Science University Receives NIH Grant for Ossicle Vibration Measurement sin Conductive Hearing Loss

      Oregon Health and Science University Receives NIH Grant for Ossicle Vibration Measurement sin Conductive Hearing Loss

      Oregon Health and Science University Receives a 2016 NIH Grant for $418,717 for Ossicle Vibration Measurement sin Conductive Hearing Loss. The principal investigator is Steven Jaques. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. The proposal develops a hand-held otoscope that uses optical coherence tomography (OCT) to image the tympanic membrane and ossicles behind an intact tympanic membrane. The system is based on spectral Fourier-domain OCT and can measure vibrations of the ossicles (malleus, incus, stapes) of the middle ear on the scale of nm to ¿m amplitude. In Aim ...

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    17. University of Iowa Receives NIH Grant for 3D Image Analysis Approach to Determine Severity and Cause of Optic Nerve Edema

      University of Iowa Receives NIH Grant for 3D Image Analysis Approach to Determine Severity and Cause of Optic Nerve Edema

      University of Iowa Receives a 2016 NIH Grant for $339,750 for 3D Image Analysis Approach to Determine Severity and Cause of Optic Nerve Edema. The principal investigator is Mona Garvin. The program began in 2013 and ends in 2018. Below is a summary of the proposed work. Currently, the clinical assessment of optic nerve swelling is limited by the subjective ophthalmoscopic evaluation by experts in order to diagnose and differentiate the cause of the optic disc edema. The long-term goal of our research effort is to develop automated 3D image-analysis approaches for the identification of an optimal set of ...

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    18. Massachusetts Institute of Technology Receives Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Receives Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Receives a 2016 NIH Grant for $288,576 for Optical Biopsy Using Optical Coherence Tomography. The principal investigator is James Fujimoto. The program began in 1997 and ends in 2019. Below is a summary of the proposed work. This is a multidisciplinary collaboration between investigators at the Massachusetts Institute of Technology and the VA Boston Healthcare System integrating imaging technology research, clinical imaging studies, medical device development and animal imaging studies. Esophageal cancer is a lethal malignancy, with a five-year survival rate of 16%. Barrett's esophagus (BE) and dysplasia are precursors to esophageal adenocarcinoma (EAC ...

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    19. Massachusetts General Hospital Receives NIH Grant for Octology: Histology using Optical Coherence Tomography

      Massachusetts General Hospital Receives NIH Grant for Octology: Histology using Optical Coherence Tomography

      Massachusetts General Hospital Receives a 2016 NIH Grant for $253,600 for Octology: Histology using Optical Coherence Tomography. The principal investigator is Burce Fischl. The program began in 2015 and ends in 2017. Below is a summary of the proposed work. While histology remains the gold standard for assessing human neuroanatomy, the procedures for sectioning and hand mounting tissue for microscopic imaging are not substantially different than they were 100 years ago. These steps introduce irremediable distortions into the tissue sections making it difficult or impossible to align sections with suffiient accuracy to create 3D histological volumes at the micron ...

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    20. Columbia University Receives NIH Grant for Structural and Functional Progression for Glaucomatous Damage to Macula

      Columbia University Receives NIH Grant for Structural and Functional Progression for Glaucomatous Damage to Macula

      Columbia University Receives a 2016 NIH Grant for $400,000 for Structural and Functional Progression for Glaucomatous Damage to Macula. The principal investigator is Carlos De Moraes. The program began in 2015 and ends in 2018. Below is a summary of the proposed work. There is compelling evidence that glaucomatous damage to the macula occurs even in early stages of the disease. The macula comprises about 30% of all retinal ganglion cells and its information corresponds to over 50% of the visual cortex. However, glaucomatous damage to the macula is often missed in clinical practice. Some of the reasons are ...

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    21. University of California at Irvine Receives NIH Grant for Phased Resolved ARF optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Receives NIH Grant for Phased Resolved ARF optical Coherence Elastography for Intravascular Imaging

      University of California at Irvine Receives a 2016 NIH Grant for $721,594 for Phased Resolved ARF optical Coherence Elastography for Intravascular Imaging. The principal investigatoor is Zhonping Chen. The program began in 2014 and ends in 2018. Below is a summary of the proposed work. The broad, long term objective of the proposed grant is to develop an integrated multimodal intravascular imaging system that combines intravascular optical coherence tomography (OCT), ultrasound (US), and phase-resolved acoustic radiation force optical coherence elastography (ARF-OCE). The multimodal intravascular imaging system is unique in that it combines the advantages of the high spatial resolution ...

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    22. Two Imaging Catheters Unite to Better Detect Dangerous Plaques in Arteries

      Two Imaging Catheters Unite to Better Detect Dangerous Plaques in Arteries

      Collaboration between two National Institute of Biomedical Imaging and Bioengineering (NIBIB)-funded labs has revealed a promising new method for identifying atherosclerotic plaques, the encased deposits in arteries that restrict blood flow and can lead to heart attack or stroke. The technique combines two different types of imaging, allowing for an unprecedented combination of depth and detail. The hybrid technology will provide doctors with a better diagnostic tool for identifying particularly problematic plaques. Heart disease is the leading cause of death worldwide. The majority of deaths from heart disease are caused by the rupture of a plaque lining an artery ...

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    23. NinePoint Medical Announces FDA 510(k) Clearance of a Real-Time Targeting Feature for the NvisionVLE® Imaging System and the First Clinical Cases in the U.S.

      NinePoint Medical Announces FDA 510(k) Clearance of a Real-Time Targeting Feature for the NvisionVLE® Imaging System and the First Clinical Cases in the U.S.

      NinePoint Medical, Inc., a transformative medical device company pioneering the use of a real-time imaging platform for gastrointestinal applications, announced today that it has received U.S. Food and Drug Administration (FDA) 510(k) clearance to market its Real-time Targeting™ feature for its flagship product, the NvisionVLE ® Imaging System. In addition, the first procedures with this new system were performed at Beth Israel Deaconess Medical Center in Boston, Massachusetts. The NvisionVLE Imaging System employs proprietary Optical Coherence Tomography (OCT) technology allowing physicians to perform a Volumetric Laser Endomicroscopy (VLE) procedure that produces real-time, high-resolution cross-sectional images. This system enables gastroenterologists ...

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    24. BIOPHOTONICS AND IMAGING SUMMER SCHOOL (BIGSS 2016)

      BIOPHOTONICS AND IMAGING SUMMER SCHOOL (BIGSS 2016)

      The Bi-annual Biophotonics and Imaging Summer School (BIGSS’16) will be held 5-9 September 2016 in Galway, Ireland. It is a five ECTS accredited course with leading professors teaching. Sessions are approx. four hours each to give a substantial grounding in the main topics of Biophotonics. The location is in the picturesque village of Ballyvaughanin the Burren . This will be augmented with hands on training at NUI Galway. Fee: €800 including courses, excursion, accommodation and food. The registration page is here: https://abbey.eventsair.com/bigss-2016/bigss2016 Interested candidates should complete the abstract template to BIGSS 2016 ( bigss2016 gmail.com ...

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