1. Optical Coherence Tomography News

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    1. Postdoctoral Positions in Biomedical Optics and Optical Coherence Tomography at the Center for Ophthalmic Optics & Lasers, Oregon Health & Science University

      Postdoctoral Positions in Biomedical Optics and Optical Coherence Tomography at the Center for Ophthalmic Optics & Lasers, Oregon Health & Science University

      Postdoctoral research opportunities are available in the area of biomedical optics at the Center for Ophthalmic Optics & Lasers ( www.COOLLab.net ) in the Casey Eye Institute, Oregon Health & Science University (OHSU). The COOL laboratory is a multidisciplinary team that incorporates optical scientists, image processing experts, ophthalmologists, statisticians, managers, and technicians. The group collaborates with several institutions to develop novel OCT technology, develop diagnostic and surgical planning software, and conduct clinical trials. The laboratory is well supported by the National Institutes of Health ( http://www.octnews.org/articles/2920025/optical-coherence-tomography-used-500m-of-federall/ ) and industry, and has brought many novel diagnostic technology into clinical ...

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    2. St. Jude Medical Announces Launch of the First International Trial to Compare OCT-Guided Stent Implantation to IVUS or Angiography-Guided PCI

      St. Jude Medical Announces Launch of the First International Trial to Compare OCT-Guided Stent Implantation to IVUS or Angiography-Guided PCI

      St. Jude Medical, Inc. (NYSE:STJ), a global medical device company, today announced the launch of the ILUMIEN III clinical trial, a prospective, international, randomized trial evaluating the clinical benefits of the company’s optical coherence tomography (OCT) guidance during stent implantation. The ILUMIEN III study will compare OCT-guided stent implantation to implantation guided by intravascular ultrasound (IVUS) or angiography alone, diagnostic tools that offer less resolution than OCT during intravascular assessments and percutaneous coronary intervention (PCI). The ILUMIEN III study is the largest multicenter randomized study to date to compare PCI outcomes associated with all three imaging tools. By ...

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    3. Optovue Introduces AngioVue OCTA in Glaucoma

      Optovue Introduces AngioVue OCTA in Glaucoma

      Optovue, a pioneer in optical coherence tomography angiography (OCTA) and leader in commercialization of the technology, announced that it has expanded the application of its OCT Angiography technology into glaucoma. After a successful introduction of the revolutionary AngioVue Imaging System to retina last year, Optovue has worked to develop clinical applications in glaucoma as well.

      The use of the AngioVue Imaging System in glaucoma was introduced at a highly successful symposium at the 6th World Glaucoma Congress in Hong Kong. The Optovue-hosted event featured presentations on the clinical applications of OCTA in glaucoma research using the company's AngioVue OCTA ...

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    4. UIUC Receives NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      UIUC Receives NIH Grant  for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      The University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $490,333 for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins. The principal investigator is Stephen Boppart. The program begain in 2012 and ends in 2017. Below is a summary of the proosed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving surgeries or lumpectomies are routinely performed. Currently, the surgeon is unable to visualize the microscopic structure at the margin, and conventionally relies on post-operative histological assessment of surgical margins to ...

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    5. MGH Postdoctoral Research Fellowship (Optical Coherence Tomography)

      MGH Postdoctoral Research Fellowship (Optical Coherence Tomography)

      Postdoctoral Research Fellowship (Optical Coherence Tomography) Massachusetts General Hospital , Boston, MA, United States Employer Description The Wellman Center is driven by a focus on solving medical problems. We have assembled a multi-disciplinary faculty with expertise in the biological, physical and clinical sciences. By cultivating inter-disciplinary collaboration, we strive to span the research spectrum from basic biological studies through the development and testing of novel diagnostic and treatment technologies to their integration into mainstream clinical practice. Job Description A Postdoctoral research fellowship in the area of optical coherence tomography (OCT) is available in the Tearney Lab at the Massachusetts General Hospital ...

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    6. Transformative clinical results with VivoSight in the diagnosis of Basal Cell Carcinoma: Data to be presented at the World Congress of Dermatology in Vancouver

      Transformative clinical results with VivoSight in the diagnosis of Basal Cell Carcinoma: Data to be presented at the World Congress of Dermatology in Vancouver

      Michelson Diagnostics, a medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, today announces that data showing significant improvement in the diagnosis of basal-cell carcinoma (BCC) using its VivoSight multibeam OCT scanner will be presented at the World Congress of Dermatology (Vancouver, June 8-13). In addition to being an efficient, non-invasive way to diagnose BCC and other non-melanoma skin cancers, using the VivoSight OCT scanner has the potential to reduce biopsies and surgery, thereby reducing scarring for patients. Joint lead investigator, Dr Martina Ulrich, CMB Collegium, Berlin, Germany, will outline the results of this independent multi-centre, prospective clinical ...

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    7. MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      MGH Receives NIH Grant To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy

      Massachusetts General Hospital Receives a 2015 NIH Grant for $472,417 To Study Natural History of Barrett's Esophagus Using Capsule Endomicroscopy. The program began in 2014 and ends in 2019. Below is a summary of the proposed work. Barrett's esophagus (BE) is a condition where normal esophageal squamous mucosa changes to metaplastic columnar mucosa in response to chronic acid reflux. BE can progress to esophageal adenocarcinoma (EAC), a prevalent (~12,000 cases per year) and deadly cancer (~15% 5-year mortality rate). Current BE management strategies of anti-reflux therapy, endoscopic screening, and regular endoscopic biopsy surveillance and ablation therapy ...

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    8. MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      MGH Receives a 2015 NIH Grant for Studying Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function

      Massachusetts General Hospital Receives a 2015 NIH Grant for $733,578 to Study Cardiac MRI-Tractography In Vivo: Integrated Imaging of Structure and Function. The principal investigator is David Sosnovik. The program began in 2013 and ends in 2017. Below is a summary of the proposed work. Pressure overload of the left and right ventricles initially leads to adaptive hypertrophy. This, however, is frequently followed by maladaptive hypertrophy, heart failure and death. We hypothesize here that changes in 3D myocardial fiber architecture play a significant role in the deleterious transition from adaptive to maladaptive hypertrophy and heart failure. We further hypothesize ...

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    9. Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives NIH Grant for Integrated Imaging of the Form and Function of the Beating Embryonic Heart

      Case Western University Receives a 2015 NIH Grant for $359,023 for Integrated Imaging of the Form and Function of the Beating Embryonic Heart. The principal investigator is Andrew Rollins. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Congenital heart defects (CHDs) afflict 36,000 babies born in the US each year and survivors often require several surgical interventions in their shortened lifetime. Despite continuous efforts, the mechanisms leading to CHDs remain largely unclear. In part, this is because most developmental cardiology studies fail to address the influential role of altered ...

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    10. Stanford University Receives NIH Grant to study Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives NIH Grant to study Molecular Imaging of Protein Glycoslation in Living Subjects

      Stanford University Receives a 2015 NIH Grant for $392,576 to study Molecular Imaging of Protein Glycoslation in Living Subjects. The principal investigator is Adan De La Zerda. The program began in 2012 and ends in 2017. Below is a summary of the propose work. The broad objective of this project is to develop instrumentation and chemistry imaging technologies to advance the study of protein glycosylation in living subjects. Protein glycosylation is the most abundant and complex posttranslational modification (PTM). Changes in protein glycosylation have been correlated with cancer progression, neurological disorders and many other diseases. Moreover, glycans are dynamic ...

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    11. Johns Hopkins University Receives NIH Grant to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives NIH Grant  to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo

      Johns Hopkins University Receives a 2015 NIH Grant for $782,083 to Study Micro Coherence Imaging Technology for Assessing Obstructive Lung Disease In Vivo. The principal investigator is Robert Brown. The program began in 2014 and ends in 2019. Below is a summary of the proposed work.

      This Biomedical Research Partnership (BRP) proposal involves a partnership among a biomedical engineering team, a pulmonary physiology team, and a clinical pulmonary medicine team. This research program will incorporate state of the art optical engineering, advanced in vivo physiologic evaluation, and direct application to human obstructive lung diseases (OLD). Optical coherence tomography (OCT ...

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    12. ZEISS Presents Its New Generation of Vascular Imaging: OCT Angiography

      ZEISS Presents Its New Generation of Vascular Imaging: OCT Angiography

      Nearly two decades ago, ZEISS was the first company to introduce optical coherence tomography (OCT) for clinical use in ophthalmology and optometry. The 20 presentations on OCT angiography by ZEISS and its research collaborators at this year’s ARVO meeting in May are testament to the company’s dedication to continued innovation and advancing the practice of medicine. ZEISS is developing OCT angiography for both spectral domain (SD) and swept source platforms. The OCT angiography application on the SD platform is currently under FDA review and is 510(k) pending. “The en face angiograms from the ZEISS SD-OCT angiography prototype ...

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    13. Leica Microsystems to Acquire OCT Company Bioptigen

      Leica Microsystems to Acquire OCT Company Bioptigen

      Integration of Optical Coherence Tomography (OCT) Opens up New Avenues for Ophthalmology and Life Science Research Leica Microsystems, a global leader in microscopy and imaging systems, has signed a definitive agreement to acquire Bioptigen, Inc. to strengthen its position in the ophthalmology market. Bioptigen is a technology leader in the field of optical coherence tomography (OCT). The integration of OCT imaging into Leica Microsystems’ surgical microscopes will assist ophthalmologists during eye surgery. Bioptigen develops and manufactures innovative OCT systems and software and is globally successful with products for clinical as well as translational research applications. Using low-power, near-infrared light, Bioptigen ...

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    14. New Data Further Emphasize the Clinical Benefits of St. Jude Medical’s OCT Technology

      New Data Further Emphasize the Clinical Benefits of St. Jude Medical’s OCT Technology

      St. Jude Medical, Inc. (NYSE:STJ), a global medical device company, today announced preliminary results from the ILUMIEN I trial and final results from the ILUMIEN II clinical study. Taken together, the findings from both studies show that with resolution up to 10 times higher than intravascular ultrasound (IVUS), optical coherence tomography (OCT) imaging can help improve stent selection and deployment, better support clinical decision-making and improve patient outcomes. Data from both studies were presented today as late-breaking clinical trials at EuroPCR 2015, and further advance the use of OCT imaging alongside percutaneous coronary intervention (PCI). During PCI procedures, physicians ...

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    15. First International OCT Angiography Summit, Portland Oregon, July 25, 2015

      First International OCT Angiography Summit, Portland Oregon, July 25, 2015

      The OCT Angiography Summit CME conference introduces the new no-injection, dye-free imaging technology to the clinical audience. OCT angiography detects the intrinsic motion contrast of blood cells and therefore does not require the injection of extrinsic contrast such as fluorescein or ICG dye. This breakthrough technology is capable of three-dimensional imaging of capillary dropout or pathologic vessel growth in the leading cause of blindness: age-related macular degeneration, diabetic retinopathy, and glaucoma. This technology may likely lead to earlier diagnosis and better treatment decisions. Meeting link http://www.octangio.net/#!oct-angiography-summit/mainPage

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    16. Avinger Announces 30-Day VISION Trial Results at EuroPCR 2015

      Avinger Announces 30-Day VISION Trial Results at EuroPCR 2015

      Avinger, Inc., (Nasdaq: AVGR ) a developer and manufacturer of image-guided, catheter-based systems for the treatment of peripheral arterial disease (PAD) and pioneer of the lumivascular approach to treating vascular disease, today announced 30-day interim results for its VISION clinical study. VISION is designed to evaluate the safety and efficacy of the Pantheris™ system to perform directional atherectomy, while for the first time ever allowing physicians to use real-time intravascular imaging to aid in the removal of plaque from diseased lower extremity arteries. Results were presented by Arne Schwindt, M.D. of St. Franziskus Hospital in Muenster, Germany at the EuroPCR ...

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    17. Micro-Tech Developing a SS-OCT Endoscopic System for Gastroenterology

      Micro-Tech Developing a SS-OCT Endoscopic System for Gastroenterology

      Micro-Tech an medical company in China established in 1999 is developing a SS-OCT endoscopic system. The system was shown at DDW 2015 and was developed by Jiefeng Xi a Principle Engineer at Micro-Tech and former PhD student at Johns Hopkins who graduated in July 2014. For more information click HERE .

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    18. University of Alabama Receives NIH Grant for Developing a Clinical and Translation Core Related to Cystic Fibrosis

      University of Alabama Receives NIH Grant  for Developing a Clinical and Translation Core Related to Cystic Fibrosis

      University of Alabama Receives a 2015 NIH Grant for $193,380 for Developing a Clinical and Translation Core related to Cystic Fibrosis. The principal investigator is steven Rowe. The program began in 2015 and ends in 2016. Below is a summary of the proposed work. Numerous investigators within the current P30 application have indicated a need for 1) primary human airway epithelial cells (from lung transplantation) or nasal epithelial cells from CF and non-CF individuals; 2) measurements of the functional anatomy of respiratory epithelia that track airway surface liquid homeostasis, ciliary beating, and mucociliary transport; or 3) CFTR bioelectric assays ...

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    19. University of Maryland Receives NIH Grant for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds

      University of Maryland Receives NIH Grant for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds

      University of Maryland Receives a 2015 NIH Grant for $320.744 for Three-Dimensional Image-Guided Development and Optimization of Molecular Regulating Bone Regenerative Scaffolds. The principal investigator is Yu Chen. Below is a summary of the propose work. Three-dimensional (3D) cell-based tissue grafts have been increasingly useful in tissue engineering and regenerative medicine. A critical building block in tissue engineering is the scaffold which can act as the supporting medium to deliver cell populations and induce the ingrowth of vessels and surrounding tissues. Therefore, it is necessary to develop tools to characterize the architecture of the scaffold. In addition, to study ...

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    20. Symposium: Incorporation of OCT Angiography into Clinical Practice, Drug Development and Clinical Trials: Opportunities and Pitfalls. June 6th 2015, Rome, Italy

      Symposium: Incorporation of OCT Angiography into Clinical Practice, Drug Development and Clinical Trials: Opportunities and Pitfalls.  June 6th 2015, Rome, Italy

      A symposium is scheduled on June 6th in Rome Italy on the Incorporation of OCT Angiography into Clinical Practice, Drug Development and Clinical Trials: Opportunities and Pitfalls. For more information click HERE .

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    21. New Clinical Data Using the NvisionVLE® Imaging System to be Presented at Digestive Disease Week® 2015

      New Clinical Data Using the NvisionVLE® Imaging System to be Presented at Digestive Disease Week® 2015

      NinePoint Medical, Inc. , an emerging leader in the development of medical devices for advanced imaging, today announced that new clinical data relating to its proprietary NvisionVLE ® Imaging System, will be presented in a series of oral and poster presentations during Digestive Disease Week ® (DDW ® ) 2015. The annual meeting will take place May 16-19th in Washington, DC. The schedule for scientific presentations related to advanced optical coherence tomography (OCT) and the NvisionVLE ® Imaging System at DDW 2015 is provided below. SATURDAY, May 16, 2015 Three posters will be presented on Saturday, May 16 at 9:30am in Hall C of Walter ...

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    22. Erasmus MC plans to appoint a PhD candidate in the field Intravascular Optical Coherence Tomography (Heartbeat OCT)

      Erasmus MC plans to appoint a PhD candidate in the field Intravascular Optical Coherence Tomography (Heartbeat OCT)

      Job description In the project Heartbeat OCT we will realize a superfast optical imaging system for use in the coronary arteries, the blood vessels around the heart. Patients who get treated after e.g. a heart attack often benefit from intravascular imaging to guide the treatment. Since the heart is a moving organ, slow imaging can cause motion blur, making the imaging less precise. If the imaging is fast enough, it is possible to image an entire artery in the short time between two heart beats, when the heart does not move. In the present project, we will develop the ...

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    23. Principal Engineer II - Software Opening at Alcon

      Principal Engineer II - Software Opening at Alcon

      Position Description: Provide technical leadership to software design, development, installation and testing solutions needed to achieve proof of concept milestones for Visualization R&D projects. Responsible for the selection, design, implementation, validation, and documentation of algorithms and tools. Will work and collaborate within multidisciplinary teams to achieve project milestones. Alcon is an Equal Opportunity Employer and participacates in E-Verify. As part of the Novartis Group of Companies, Alcon takes pride in maintaining a diverse environment and our policies are not to discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin ...

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