1. Optical Coherence Tomography News

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    1. PhD studentship in AI-Enabled OCT at Liverpool University, UK

      PhD studentship in AI-Enabled OCT at  Liverpool University, UK

      An EPSRC funded PhD studentship is available in the Laboratory of Professor Shen of Department of Electrical Engineering and Electronics, Liverpool University, UK. This project aims to develop artificial intelligence (AI)-enabled OCT techniques for imaging the corneal nerves in a non-contact manner. The candidate will be expected to refine and optimise the novel OCT instrumentation to achieve the required resolution and speed for imaging corneal nerves. The successful PhD candidate will benefit from working with a multidisciplinary team covering areas of imaging technology, AI and computer science, tissue engineering and medicine. Applicants should have (or expect to obtain by ...

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    2. Asclepix Therapeutics partners with Notal Vision on Home OCT remote monitoring in DME and AMD clinical trials

      Asclepix Therapeutics partners with Notal Vision on Home OCT remote monitoring in DME and AMD clinical trials

      Notal Vision, Inc. announced today that the company will provide AsclepiX Therapeutics with Home OCT monitoring services through its Notal Vision Diagnostic Clinic to support AsclepiX’s AXT107 phase 1 clinical trial program. The exploratory application of the investigational home monitoring platform will add new valueable data points between the regulary scheduled study office visits. Study subjects with diabetic macular edema (DME) and wet age-related macular degeneration (AMD), who participate in the CONGO and SHASTA study sponsored by AsclepiX Therapeutics, will perform sequential daily self-imaging of their eyes with the user-friendly, self-operated Notal Home OCT device in their homes. The ...

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    3. Postdoc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Ocular Imaging Laboratory at University of California, Davis

      Postdoc Position for Biomedical Engineer / Vision Scientist in the UC Davis EyePod - Small Animal Ocular Imaging Laboratory at University of California, Davis

      Applications are invited for a post-doctoral research associate position in the UC Davis EyePod Small Animal Ocular Imaging Laboratory affiliated with Center for Vision Science ( http://cvs.ucdavis.edu ) at the UC Davis Main Campus. The goal of our research is to develop and translate the next generation in vivo cellular resolution multimodal retinal imaging instruments and data analysis tools from basic science to clinics and to apply them to in vivo study of disease mechanisms and therapeutic interventions. The ideal candidate will have strong skills in some combination of retinal/microscopic imaging modalities, including OCT, SLO, multispectral imaging, fluorescence ...

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    4. Join Thorlabs for an OCT-Focused Webinar March 8th, 2021!

      Join Thorlabs for an OCT-Focused Webinar March 8th, 2021!

      Thorlabs’ OCT team is excited to present a new products webinar as part of its virtual BiOS and Photonics West activities. Join Dr. Michael Leitner for this one-hour event on March 8 at 11:30 AM EST, which will include a live Q&A session. To register, please visit this link . After the event, a recorded version will be available at www.thorlabs.com/webinars . Abstract: Thorlabs is excited to feature our complete selection of Optical Coherence Tomography (OCT) systems, which includes both spectral domain (SD) and swept source (SS) options. This talk will showcase biomedical and industrial applications and ...

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    5. MedLumics raises $21.8M to test its optically guided heart ablation catheter

      MedLumics raises $21.8M to test its optically guided heart ablation catheter

      The Madrid-based company’s AblaView system is equipped with sensors that use optical coherence tomography—an imaging technique using light to scan and penetrate a few millimeters of tissue—to directly observe the creation of ablation lesions in the cardiac muscle wall in real time and assure the correct placement of the catheter’s electrodes. The proceeds will help carry MedLumics into first-in-human clinical testing, following the preclinical feasibility studies it completed last year, the company said. The fundraising was backed by Asabys Partners, Kurma Partners, VI Partners Swiss Innovation, CDTI Innvierte Economía, Andera Partners, Caixa Capital Risc and ...

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      Mentions: MedLumics
    6. Johns Hopkins University Receives NIH Grant for Artificial Intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Kerotoplasty (Auto-Dalk)

      Johns Hopkins University Receives NIH Grant for Artificial Intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Kerotoplasty (Auto-Dalk)

      Johns Hopkins University Receives a 2021 NIH Grant for $409,997 for Artificial Intelligence Optical Coherence Tomography Guided Deep Anterior Lamellar Kerotoplasty (Auto-Dalk). The principal investigator is Jin U. Kang. Below is a summary of the proposed work. Contemporary ocular surgeries are performed by skilled surgeons through operating microscopes, utilizing freehand techniques and manually operated precision micro-instruments, where the outcomes are often limited by the surgeon's skill levels and experiences. To overcome these human factors, we have assembled an interdisciplinary team including a clinician-scientist and eye surgeon, an optical device scientist and medical robotic engineers to translate existing and ...

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    7. Oregon Science and Health University Receives NIH Grant for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases

      Oregon Science and Health University Receives NIH Grant  for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases

      Oregon Science and Health University Receives a 2021 NIH Grant for $440,684 for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases. The principal investigator is David Huang. Below is a summary of the proposed work. Optical coherence tomography (OCT) is uniquely able to achieve micron depth resolution while imaging a large 3-dimensional (3D) volume. This enables 3D imaging and precise measurements in the anterior segment of the eye, including the cornea, conjunctiva, sclera, anterior chamber, iris, and crystalline lens. Anterior segment OCT is already widely used in ophthalmology. But a number of high-impact applications were held back ...

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    8. Teledyne SP Devices Announces 12-bit Digitizer with 7 Gbyte/s Sustained Data Transfer Rate

      Teledyne SP Devices Announces 12-bit Digitizer with 7 Gbyte/s Sustained Data Transfer Rate

      Teledyne SP Devices, a business unit of Teledyne Technologies Incorporated (NYSE: TDY), today announced the release of ADQ32 – a fourth-generation modular data acquisition board optimized for high-throughput applications. The combination of on-board open field-programmable gate array (FPGA) and high-speed data streaming makes it ideal even for the most computationally demanding applications. The dual-channel 12-bit digitizer supports synchronous sampling at 2.5 gigasamples per second (GS/s) on each channel and features an open Xilinx Kintex Ultrascale KU040 field-programmable gate array (FPGA). ADQ32 is streamlined for high-volume applications and is therefore suitable for integration by original equipment manufacturers (OEMs) in areas ...

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    9. Spectrawave Raises $13.2M for Intracoronary Imaging Solution

      Spectrawave Raises $13.2M for Intracoronary Imaging Solution

      SpectraWave today announced a $13.2 million Series A-2 financing to support completion of product development and regulatory filing for its flagship intracoronary imaging product, designed to help physicians optimize coronary stenting interventions and limit future adverse events. The funding round is led by prior investor Deerfield Management, and includes follow-on investment from prior unnamed seed investors. Coronary artery disease (CAD), the buildup of plaque in the wall of the coronary arteries that supply blood to the heart, causes 9 million deaths worldwide each year. In CAD, patients can undergo stent placement to relieve symptoms, but one in five patients ...

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    10. PhD Studentship in High Resolution Retinal Imaging The Ohio State University

      PhD Studentship in High Resolution Retinal Imaging The Ohio State University

      A NIH funded PhD studentship is available in the laboratory of Drs. Nathan Doble and Stacey Choi in the College of Optometry/Department of Ophthalmology and Visual Science at The Ohio State University (OSU). The successful candidate will enroll in the PhD program in Vision Science at The Ohio State University and conduct their dissertation work within a highly collaborative research environment focused on the development and use of novel high-resolution optical instrumentation for the study of retinal structure and function. The candidate will be expected to assist with construction and validation of novel instrumentation as well as the collection ...

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    11. Postdoctoral Research Fellowships (Machine Vision/Image Analysis) at Massachusetts General Hospital

      Postdoctoral Research Fellowships (Machine Vision/Image Analysis) at Massachusetts General Hospital

      Employer Description Guillermo J. Tearney, M.D., Ph.D. Tearney Lab – Wellman Center for Photomedicine Massachusetts General Hospital Until recently, visualizing the architectural and cellular morphology of human tissue has required histopathological examination. Samples would be excised from the patient, processed, sectioned, stained and viewed under a microscope. In addition to being invasive, time consuming and costly, the static nature of conventional pathology prohibits the study of biological dynamics and function. The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities ...

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    12. Postdoctoral Research Fellowships (In Vivo Microscopy) at Massachusetts General Hospital

      Postdoctoral Research Fellowships (In Vivo Microscopy) at Massachusetts General Hospital

      Employer Description Guillermo J. Tearney, M.D., Ph.D. Tearney Lab – Wellman Center for Photomedicine Massachusetts General Hospital Until recently, visualizing the architectural and cellular morphology of human tissue has required histopathological examination. Samples would be excised from the patient, processed, sectioned, stained and viewed under a microscope. In addition to being invasive, time consuming and costly, the static nature of conventional pathology prohibits the study of biological dynamics and function. The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities ...

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    13. Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital

      Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital

      Employer Description Guillermo J. Tearney, M.D., Ph.D. Tearney Lab – Wellman Center for Photomedicine Massachusetts General Hospital Until recently, visualizing the architectural and cellular morphology of human tissue has required histopathological examination. Samples would be excised from the patient, processed, sectioned, stained and viewed under a microscope. In addition to being invasive, time consuming and costly, the static nature of conventional pathology prohibits the study of biological dynamics and function. The Tearney Laboratory at Massachusetts General Hospital has led the way in transforming the current diagnostic paradigm through the invention and translation of new noninvasive, high-resolution optical imaging modalities ...

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    14. Post-doctoral Scholar Position in OCT Endoscopy at the University of North Carolina at Chapel Hill

      Post-doctoral Scholar Position in OCT Endoscopy at the University of North Carolina at Chapel Hill

      The Coherence Imaging Laboratory at the University of North Carolina at Chapel Hill seeks a highly motivated Postdoc to perform research in optical coherence tomography (OCT) imaging. Research activities will include the development and application of our endoscopic OCT imaging systems for upper airway imaging, and its application for assessment of airway injury and upper airway disorders. Candidates are required to have demonstrated expertise with imaging hardware and hardware design, with particular consideration given to candidates with experience using fiber optics, fabricating fiber optic tips, using and setting up interferometers or similar optical systems, and setting up data acquisition systems ...

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    15. Postdoctoral Research Fellowship at Nanyang Technological University, Singapore

      Postdoctoral Research Fellowship at Nanyang Technological University, Singapore

      A Postdoctoral Research Fellow position is available in the School of Chemical and Biomedical Engineering (SCBE) at Nanyang Technological University (NTU), Singapore. Led by Dr. Tong Ling ( https://dr.ntu.edu.sg/cris/rp/rp01295 ), we are seeking highly motivated applicants in biomedical engineering, electrical engineering, physics, or other related disciplines, to develop high-speed interferometric imaging techniques for functional neuroimaging in the retina. The fellowship will be working in close collaborations with the SERI-NTU Advanced Ocular Engineering (STANCE) Laboratory and the Singapore Eye Research Institute (SERI). Nanyang Technological University (NTU), Singapore ranked 13 th in the QS World University Rankings ...

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    16. Avinger Initiates Full Commercial Launch of Tigereye Image-Guided CTO Crossing Catheter

      Avinger Initiates Full Commercial Launch of Tigereye Image-Guided CTO Crossing Catheter

      Avinger, Inc. (NASDAQ:AVGR), a commercial-stage medical device company marketing the first and only intravascular image-guided, catheter-based system for diagnosis and treatment of Peripheral Artery Disease (PAD), today announced full commercial launch of its Tigereye™ image-guided chronic total occlusion (CTO) crossing system. With the initiation of full commercial launch, current and prospective accounts throughout the US and Germany are now able to order the Tigereye device. During the fourth quarter of 2020, Avinger conducted a limited launch at 12 clinical centers in the U.S. and Germany. Approximately 50 CTO cases were successfully performed, showcasing Tigereye's advanced clinical capabilities ...

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      Mentions: Avinger
    17. The Thorlabs OCT team is proud to present a webinar given by Dr. Brendan Kennedy from the University of Western Australia - January 20, 2021

      The Thorlabs OCT team is proud to present a webinar given by Dr. Brendan Kennedy from the University of Western Australia - January 20, 2021

      The Thorlabs OCT team is proud to present a webinar given by Dr. Brendan Kennedy from the University of Western Australia. This live event will take place on January 20 at 3pm GMT and include a Q&A session. For information and registration please visit this link : After the event a recorded version will be available at www.thorlabs.com/webinars . Abstract: Elastography and related methods to image the mechanical properties of tissue have been developed across a range of spatial scales, from the cellular, for example, using atomic force microscopy, through to the whole organ, using ultrasound elastography and ...

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    18. Heidelberg Engineering Emphasizes Anterior Segment Focus under New Clinical Director

      Heidelberg Engineering Emphasizes Anterior Segment Focus under New Clinical Director

      Steve Thomson joins Heidelberg Engineering as Clinical Director to further strengthen the Anterior Segment product development team. He will concentrate on the integration of data and images into increasingly efficient and effective anterior segment workflows for clinical practice. Steve Thomson assumes his new role as Clinical Director – Anterior Segment effective January 1, 2021. He has a background in ophthalmic imaging followed by more than 30 years’ professional experience in the ophthalmic industry. Steve is a knowledgeable and respected anterior segment expert with an in-depth comprehension of clinical ophthalmology, as well as all the diagnostic and surgical technologies involved. Steve’s ...

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    19. Massachusetts General Hospital Receives NIH Grant for Unique Value of Real-Time Shear Stress to Enhance Coronary Disease Management

      Massachusetts General Hospital Receives NIH Grant for Unique Value of Real-Time Shear Stress to Enhance Coronary Disease Management

      Massachusetts General Hospital Receives a 2021 NIH Grant for $729,926 for Unique Value of Real-Time Shear Stress to Enhance Coronary Disease Management. The principal investigator is Guillermo Tearney. Below is a summary of the proposed work. Management of CAD is hindered by our inability to investigate fundamental pathobiologic processes that lead to individual coronary plaque progression, destabilization, and adverse clinical events. A critical mechanism responsible for plaque behavior is local endothelial shear stress (ESS), the frictional force of blood flowing across the endothelium, which is governed by the artery’s detailed local geometry. Focal regions of low ESS drive ...

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    20. Washington University in St. LouisReceives NIH Grant for High-Throughput Integrated Live Imaging and Optogentic Pacing Platform to Assess Hypoxia Responsiveness in the Fly Heart

      Washington University in St. LouisReceives NIH Grant for High-Throughput Integrated Live Imaging and Optogentic Pacing Platform to Assess Hypoxia Responsiveness in the Fly Heart

      Washington University Receives a 2021 NIH Grant for $529,434 for High-Throughput Integrated Live Imaging and Optogentic Pacing Platform to Assess Hypoxia Responsiveness in the Fly Heart. The principal investigator is Chao Zhou. Below is a summary of the proposed work. Ischemic preconditioning is a well-established phenomenon, in which a brief episode(s) of controlled ischemia and reperfusion renders cardioprotection from a subsequent sustained episode of ischemia. An emerging body of evidence demonstrated that neural regulated heart rate modulation confers cardiac preconditioning responses. Understanding the mechanism through model systems of preconditioning would help us identify the genes and proteins when ...

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    21. University of California at San Diego Receives NIH Grant for OCT in the Ocular Hypertension Treatment Study: 20 Year Follow-Up

      University of California at San Diego Receives NIH Grant for OCT in the Ocular Hypertension Treatment Study: 20 Year Follow-Up

      University of California at San Diego Receives a 2021 NIH Grant for $182,600 for OCT in the Ocular Hypertension Treatment Study: 20 Year Follow-Up. The principal investigator is Linda Zangwill. Below is a summary of the proposed work. The “Ocular Hypertension Treatment Study (OHTS 3): 20-year follow-up (Phase 3)” was designed to determine the incidence and severity of primary open angle glaucoma (POAG) in the longstanding OHTS cohort. and determine the frequency and severity of functional limitations associated with POAG. Moreover, this well-characterized cohort has precise information on the dates/timing of the development of POAG assessed by 3 ...

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    22. Massachusetts General Hospital Receives NIH Grant for Early Detection and Diagnosis of Lung Cancer with Endomicroscopy

      Massachusetts General Hospital Receives NIH Grant for Early Detection and Diagnosis of Lung Cancer with Endomicroscopy

      Massachusetts General Hospital Receives a 2021 NIH Grant for $662,413 for Early Detection and Diagnosis of Lung Cancer with Endomicroscopy. The principal investigator is Melissa Suter. Below is a summary of the proposed work. Early diagnosis of lung cancer is critical to patient survival. Unfortunately the vast majority of cases are detected once symptoms arise and the cancer has spread offering patients little hope for cure (average 5-year survival rate < 15%). The U.S. Preventive Services Task Force recommends individuals at high risk of developing lung cancer undergo yearly screening with low dose computed tomography (LDCT). Screening is highly ...

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    23. University of Southern California Receives NIH Grant for Mechanisms of Cochlear Synaptopathy After Noise or Blast Trauma

      University of Southern California Receives NIH Grant for Mechanisms of Cochlear Synaptopathy After Noise or Blast Trauma

      University of Southern California Receives a 2021 NIH Grant for $606,342 for Mechanisms of Cochlear Synaptopathy After Noise or Blast Trauma. The principal investigator is John Oghalai. Below is a summary of the proposed work. About 15% of Americans have hearing loss due to noise exposure. The classical explanation is trauma to the cochlear hair cells. An additional mechanism of noise-induced hearing loss is cochlear synaptopathy. There are no effective treatments used clinically to prevent hearing loss via either mechanism after traumatic noise exposure. Recently, we identified that endolymphatic hydrops occurs after blast or noise trauma, and that endolymphatic ...

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    24. Dohney Eye Institute Receives NIH Grant for Artificial Intelligence for Assessment of Stargardt Macular Atrophy

      Dohney Eye Institute Receives NIH Grant for Artificial Intelligence for Assessment of Stargardt Macular Atrophy

      Dohney Eye Institute Receives a 2021 NIH Grant for $176,625 for Artificial Intelligence for Assessment of Stargardt Macular Atrophy. The principal investigator is Zhihong Hu. Below is a summary of the proposed work. Stargardt disease is the most frequent form of inherited juvenile macular degeneration. Fundus autofluorescence (FAF) is a widely available imaging technique which may aid in the diagnosis of Stargardt disease and is commonly used to monitor its progression. FAF imaging provides an in vivo assay of the retinal layers, but is only an indirect measure. Spectral-domain optical coherence tomography (SD-OCT), in contrast, provides three-dimensional visualization of ...

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