1. Optical Coherence Tomography News

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    1. Study shows new technology may improve management of leading causes of blindness

      Study shows new technology may improve management of leading causes of blindness

      Research published today in the Proceedings of the National Academy of Sciences (PNAS) demonstrates that technology invented by researchers at Oregon Health & Science University's Casey Eye Institute can improve the clinical management of the leading causes of blindness. Optical coherence tomography (OCT) angiography could largely replace current dye-based angiography in the management of these diseases. OHSU researchers found that OCT angiography has considerable advantages over conventional techniques for the diagnosis and management of macular degeneration, diabetic eye disease and glaucoma, the leading causes of blindness in the United States. "This is a significant breakthrough technology that could fundamentally change ...

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    2. Swept Source Optical Coherence Tomography in Ocular Diseases Special Interest Group at ARVO

      Swept Source Optical Coherence Tomography in Ocular Diseases Special Interest Group at ARVO

      Moderators: Ludwig M. Heindl(Center of Ophthalmology, University Hospital Cologne, Cologne, Germany) Robert J. Zawadzki (UC Davis Eye Center, University of California Davis, Sacramento, California, US) Speakers: Olaf Meiendresch (Topcon Medical, Willich, Germany) Albert Caramoy (Center of Ophthalmology, University Hospital Cologne, Cologne, Germany) Robert J. Zawadzki (UC Davis Eye Center, Sacramento, USA) Ireneusz Grulkowski (Nicolaus Copernicus University, Torun, Poland Wolfgang Drexler (Medical University of Vienna, Vienna Austria) Robert Huber (Institute of Biomedical Optics, University zu Lübeck, Germany) Organizing Section: Anatomy and Pathology/Oncology (AP) Contributing Sections: Cornea (CO), Glaucoma (GL), Retina (RE), Multidisciplinary Ophthalmic Imaging Group (MOI) Imaging using ...

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    3. Feature Of The Week 4/20/2015: Optical Coherence Photoacoustic Microscopy for In Vivo Multimodal Retinal Imaging

      Feature Of The Week 4/20/2015: Optical Coherence Photoacoustic Microscopy for In Vivo Multimodal Retinal Imaging

      We developed an optical coherence photoacoustic microscopy (OC-PAM) system, which can accomplish optical coherence tomography (OCT) and photoacoustic microscopy (PAM) simultaneously by using a single pulsed broadband light source. With a center wavelength of 800 nm and a bandwidth of 30 nm, the system is suitable for imaging the retina. Generated from the same group of photons, the OCT and PAM images are intrinsically registered in the lateral directions. To test the capabilities of the system on multimodal ophthalmic imaging, we imaged the retina of pigmented rats. The OCT images showed the retinal structures with quality similar to conventional OCT ...

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    4. Heidelberg Engineering Announces 85,000 Hz OCT2; Next Generation SPECTRALIS OCT Module

      Heidelberg Engineering Announces 85,000 Hz OCT2; Next Generation SPECTRALIS OCT Module

      Heidelberg Engineering announces significant improvements to the SPECTRALIS ® OCT2 Module. The OCT2 Module brings the next generation OCT technology to the SPECTRALIS diagnostic imaging platform. It combines a high scan rate with Heidelberg Engineering’s proprietary TruTrack Active Eye Tracking, to provide unmatched image quality and significantly improved acquisition speed. New applications such as OCT Angiography* will build on the OCT2 Module. Since its debut at the 2014 American Academy of Ophthalmology in Chicago, the OCT2 Module is an option for all new SPECTRALIS models. In addition, a large number of SPECTRALIS devices in use, depending on their technical specifications ...

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    5. Senior Systems Engineer Opening at NinePoint Medical

      Senior Systems Engineer Opening at NinePoint Medical

      The Company NinePoint Medical is positioned to improve patient care through the development of medical devices that enable high-resolution in-vivo imaging. Using advanced optical technologies, NinePoint Medical empowers treating physicians and pathologists to image cross-sectionally and visualize features at and below the tissue surface. Job Summary We are looking for a talented Senior Systems Engineer who will be responsible for developing future medical device platforms, and supporting existing technologies. Key Responsibilities: Execution of diverse tasks related to the development of complete integrated systems (console & optical probes): from concept and development through commercialization. Define, develop, and document system- and subsystem-level requirements ...

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    6. HAAG-STREIT SURGICAL: iOCT® camera receives 510(k) clearance

      HAAG-STREIT SURGICAL: iOCT® camera receives 510(k) clearance

      HAAG-STREIT SURGICAL announced its intraoperative-OCT camera has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for marketing on the largest medical device market in the world. The intraoperative Optical Coherence Tomography (iOCT®) is already being successfully used for cataract operations, lamellar keratoplasties, membrane peelings, and for the treatment of retinal disorders. The ASCRS congress, to be held in San Diego (18 – 21 April 2015), marks the launch of the iOCT® system in the US. During the course of the surgical procedure, the iOCT® system allows non-invasive, contact-free imaging so that the structures and layers within ...

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    7. Wasatch Photonics launches travel grants to celebrate International Year of Light

      Wasatch Photonics launches travel grants to celebrate International Year of Light

      Wasatch Photonics Inc. , a leading provider for gratings, spectrometer and optical coherence tomography instrumentation, is celebrating the International Year of Light and Light-based Technologies by launching its Travel and Publication Grant Program. The United Nations General Assembly proclaimed 2015 to be the International Year of Light and Light-based Technologies in December 2013. Mike Sullivan, general manager of Wasatch Photonics, said the Wasatch program supports research exchange by providing special grants to some of its customers for travel to academic meetings and publications. "The grants will support part of travel or publication cost. Wasatch has made it clear that while the ...

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    8. University of Texas, Austin Receives NIH Grant for Optical Imaging of Baseline Blood Flow and Oxygenation During Stroke

      University of Texas, Austin Receives NIH Grant for Optical Imaging of Baseline Blood Flow and Oxygenation During Stroke

      University of Texas, Austin Receives a 2015 NIH Grant for $465,127 for Optcial Imaging of Baseline Blood Flow and Oxygenation During Stroke. The principal investigator is Andrew Dunn. The program began in 2010 and ends in 2019. Below is a summary of the proposed work. Quantitative imaging of cerebral blood flow is essential in preclinical stroke studies for monitoring the efficacy of potential treatments and for understanding the role of vascular reorganization in functional recovery. Similarly, real-time imaging of blood flow is crucial during neurovascular surgery in humans, where intraoperative visualization of vascular patency and tissue perfusion are needed ...

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    9. National Research Council of Canada Receives NIH Grant for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization

      National Research Council of Canada Receives NIH Grant for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization

      National Research Council of Canada Receives NIH Grant for $208,382 for Validating OCT and Raman Spectrosopy for Assessment of Tooth De/Remineralization. The principal investigator is Michale Sowa. The program began in 2006 and ends in 2017. Below is a summary of the proposed work. Dental caries continues to be prevalent in children and youth, with significant oral health disparities existing in some population groups. This disease arises when the balance between pathological factors (e.g. cariogenic bacteria) and protective factors (e.g. saliva flow) is tipped in favour of demineralization. The prevalence of caries suggests that the disease ...

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    10. Stanford University Receives a NIH Grant for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo

      Stanford University Receives a  NIH Grant for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo

      Stanford University Receives a 2015 NIH Grant for $448,758 for Optical Coherence Tomography for 3D Measurements of Cochlear Mechanics In Vivo. The principal investigator is John Oghalai. The program began in 2015 and ends in 2020. Below is a summary of the proposed work. The function of the cochlea is to transduce complex sound pressure waves into electrical signals. Organ of Corti vibration is based upon a complex interplay between passive mechanical structures and active OHC- based processes. While laser Doppler vibrometry has added tremendously to our understanding of cochlear physiology, this technique is limited. Only motion from one ...

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    11. Georgetown University Receives NIH Grant for Non-Invasive Evaluation of Transplant Kidney using OCT

      Georgetown University Receives NIH Grant  for Non-Invasive Evaluation of Transplant Kidney using OCT

      Georgetown University Receives a 2015 NIH Grant for $388,865 for Non-Invasive Evaluation of Transplant Kidney using OCT. The principal investigator is Peter Andrews. The program began in 2014 and ends in 2016. Below is a summary of the proposed work. There is currently a worldwide shortage of kidneys for transplantation due mainly to the fact that there is no reliable means to determine their viability (i.e., kidneys stored for long periods of time, etc.). Also, following transplantation, kidneys oftn do not function immediately and their status is unclear. Previously, we have shown that the histopathology of living, superficial ...

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    12. Researchers develop high-resolution technique for non-invasively imaging hidden layers in centuries-old paintings

      Researchers develop high-resolution technique for non-invasively imaging hidden layers in centuries-old paintings

      A painting hanging on the wall in an art gallery tells one story. What lies beneath its surface may tell quite another. Often in a Rembrandt, a Vermeer, a Leonardo, a Van Eyck, or any other great masterpiece of western art, the layers of paint are covered with varnish, sometimes several coats applied at different times over their history. The varnish was originally applied to protect the paint underneath and make the colors appear more vivid, but over the centuries it can degrade. Conservators carefully clean off the old varnish and replace it with new, but to do this safely ...

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    13. Michelson Diagnostics Appoints Peter Senger as Country Manager Germany

      Michelson Diagnostics Appoints Peter Senger as  Country Manager Germany

      Michelson Diagnostics, the UK based medical device company focused on multi-beam Optical Coherence Tomography (‘OCT’) technology, today announces the appointment of Peter Senger as Country Manager Germany, with immediate effect. Peter, aged 46, has more than 25 years’ experience in sales and marketing and over 15 years of commercial experience in the medical device industry in Germany, with a track record of building early stage businesses with new and disruptive technologies. Most recently, Peter was Regional Business Manager at AngioDynamics, where he was instrumental in the introduction of the NanoKnife ® System into Germany and helped to secure reimbursement for the ...

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    14. Duke University Receives NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health

      Duke University Receives NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health

      Duke University Receives a 2015 NIH Grant for Novel Determination of Microbicide PK in Women's Reproductive Health. The principal investigator is David Katz. The program began in 2012 and ends in 2016. Below is a summary of the proposed work. Vaginal microbicides offer much promise to prevent sexual transmission of HIV. The pharmacokinetics (PK) of a product (active pharmaceutical ingredient + dosage form) is central to prophylactic functionality (PD). But our ability to measure and predict microbicide PK is currently limited. Further, microbicide PD depends on how product + dosage regimen accommodate a range of conditions of the vaginal environment. These ...

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      Mentions: Duke University
    15. Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography. The principal investigator is James Fujimoto. The program began in 1985 and ends in 2020. Below is a summary of the propose work. This proposal is a resubmission of a competing renewal application for an ongoing collaborative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye Center. This is a multidisciplinary program which integrates imaging technology research, clinical and small animal imaging studies. The specific aims are: Aim 1. Next generation OCT technology ...

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    16. UC Irvine Receives a 2015 NIH grant for Combined OCT/US/PAT System for Intravascular Imaging

      UC Irvine Receives a 2015 NIH grant for Combined OCT/US/PAT System for Intravascular Imaging

      University of California Irvine Receives a 2015 NIH grant for Combined OCT/US/PAT System for Intravascular Imaging. The principal investigator is Zhongping Chen. The program begain in 2015 and ends in 2019. Below is a summary of the propose work.

      Atherosclerosis is a progressive disease that is characterized by the accumulation of lipids, cholesterol, fibrous constituents, monocytes, and various other inflammatory cells in the arterial wall. Atherosclerosis is one of the major causes of morbidity and mortality in developed countries. The major cause of deaths from heart attacks (86%) and brain aneurysm (45%) are due to "vulnerable plaques" that ...

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    17. VA North Texas Health Care System Receives NIH Grant for Prasugrel for Prevention of Early Saphenous Vein Grant Thrombosis.

      VA North Texas Health Care System Receives NIH Grant for Prasugrel for Prevention of Early Saphenous Vein Grant Thrombosis.

      VA North Texas Health Care System Receives a 2015 NIH Grant for Prasugrel for Prevention of Early Saphenous Vein Grant Thrombosis. The principal investigator is Emmanouil Brilakis. The program began in 2012 and ends in 2016. Below is a summary of the proposed work. Early aortocoronary saphenous vein bypass graft (SVG) failure is common and is associated with high morbidity and mortality. Aspirin significantly reduces the incidence of early saphenous vein graft failure, whereas clopidogrel use provided conflicting results in small randomized studies. Prasugrel is a novel thienopyridine that provides more rapid, consistent, and intense platelet inhibition than clopidogrel. However ...

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    18. Texas Engineering Experiment Station Receives NIH Grant for Morphological and Molecular Imaging System for In Vivo Atherosclerosis Research

      Texas Engineering Experiment Station Receives NIH Grant for Morphological and Molecular Imaging System for In Vivo Atherosclerosis Research

      Texas Engineering Experiment Station Receives a 2015 NIH Grant for Morphological and Molecular Imaging System for In Vivo Atherosclerosis Research. The Principal invesigator is Brian Applegate. The program began in 2012 and ends in 2017. Below is a summary of the proposed work.

      Atherosclerosis is the leading cause of morbidity and mortality in the United States and is characterized as a systemic, progressive disease process in which the arterial wall thickens through a process of inflammation, oxidative stress, and dyslipidemia. This process leads to plaque formation and flow limitation in the vessel lumen. The sudden rupture of this arterial plaques ...

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    19. Systems Engineer Position Opening at Topcon Medical Systems in Oakland, New Jersey

      Systems Engineer Position Opening at Topcon Medical Systems in Oakland, New Jersey

      An exciting opportunity for a highly motivated system engineer to work creatively within a dedicated R&D laboratory (Topcon Advanced Biomedical Imaging Laboratory, Oakland, NJ) contributing to interdisciplinary projects with global impact. Primary responsibilities include system development for ophthalmic imaging devices, supporting both prototype and commercial system development efforts. The position requires diverse engineering and programming experience including system integration, data acquisition and test equipment control, signal and image processing, and image analysis algorithm development. While this position has an emphasis on system development, the successful candidate is also expected to participate in advanced ophthalmic imaging techniques and imaging analysis ...

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    20. Feature Of The Week 04/05/15: Noninvasive in vivo Imaging Reveals Differences Between Tectorial Membrane and Basilar Membrane Traveling Waves in the Mouse Cochlea

      Feature Of The Week 04/05/15: Noninvasive in vivo Imaging Reveals Differences Between Tectorial Membrane and Basilar Membrane Traveling Waves in the Mouse Cochlea

      Sound is encoded within the auditory portion of the inner ear, the cochlea, after propagating down its length as a traveling wave. For over half a century, vibratory measurements to study cochlear traveling waves have been made using invasive approaches such as laser Doppler vibrometry. While these studies have provided critical information regarding the non-linear processes within the living cochlea that increase the amplitude of vibration and sharpen frequency tuning, the data have typically been limited to point measurements of basilar membrane vibration. In addition, opening the cochlea may alter its function and affect the findings. Here we describe volumetric ...

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    21. The Arden Photonics OCT validation Phantom

      The Arden Photonics OCT validation Phantom

      The Arden Photonics OCT validation Phantom has been developed to assure the performance standards of your instruments throughout their life. This unique product uses a laser-inscribed calibration pattern embedded in a stable silica substrate, allowing inspection with an optical microscope. Independent verification can therefore, easily be used to check the accuracy of the phantom when conducting tests. With the OCT validation Phantom from Arden Photonics, you can be assured of the accuracy of your OCT images. Features and benefits: Four different patterns in one small slide gives comprehensive assessment of your OCT instrumentation Patterns laser-inscribed in silica for excellent stability ...

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      Mentions: Arden Photonics
    22. Columbia University Receives NIH Grant for Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration

      Columbia University Receives NIH Grant for Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration

      Columbia University Receives a 2015 NIH Grant for $281,840 for Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration. The principal investigator is Ronald Silverman. The program began in 2012 and ends in 2016. Below is a summary of the proposed work. Age-related macular degeneration (AMD) is a disease of the retinal pigment epithelium characterized by the appearance of protein/lipid deposits (drusen), geographic atrophy and neovascularization. Techniques currently used for diagnostic imaging of AMD include indocyanine green dye or fluorescein angiography, autofluorescence imaging and optical coherence tomography (OCT). OCT images depict optical backscatter, caused by variation in ...

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    23. Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Position description: A full-time Postdoctoral Associate position in Biophotonics / Biomedical Optical Imaging is available at Lehigh University starting ASAP . The primary purpose of this position will be for a highly motivated individual to develop advanced optical imaging techniques for novel biomedical applications in vitro and/or in vivo . Compensation is commensurate with experience. Qualifications: Ph.D. in Electrical Engineering, Physics, Applied Physics, Biomedical Engineering / Bioengineering or related fields. Hands-on experience with optical coherence tomography (OCT), especial swept-source OCT, is preferred. Good publication record and communication skills. Strong programming skills (Matlab, Labview, C++ and GPU programming) are pluses. Research areas: The ...

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    24. Feature Of The Week 03/29/15: University of Washington Demonstrates In vivo Microvascular Imaging of Human Oral and Nasal Cavities using SS-OCT

      Feature Of The Week 03/29/15: University of Washington Demonstrates In vivo Microvascular Imaging of Human Oral and Nasal Cavities using SS-OCT

      Over decades, optical coherence tomography (OCT) has proven useful in the diagnosis of cavity disorders through in vivo feasibility or clinical studies in human. OCT studies have evaluated changes in cavity tissue morphology and optical properties of backscattered OCT signals from cavity tissue layers for the identification of abnormalities. Notwithstanding, there has been limited discussion regarding the assessment of microvasculature in human cavity tissues. The microcirculation within cavity tissues would be an invaluable indicator for assessing cavity disorders due to vascular malformation associated with disease progression. In this work, we report three-dimensional (3D) imaging of microcirculation within human cavity tissues ...

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