1. Articles from Buyun Zhang

    1-4 of 4
    1. Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature

      Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature

      Endoscopic imaging technologies, such as endoscopic optical coherence tomography (OCT) and near-infrared fluorescence, have been used to investigate vascular and morphological changes as hallmarks of early cancer in the gastrointestinal tract. Here we developed a high-speed multimodality endoscopic OCT and fluorescence imaging system. Using this system, the architectural morphology and vasculature of the rectum wall were obtained simultaneously from a Sprague Dawley rat in vivo . This multimodality imaging strategy in a single imaging system permits the use of a single imaging probe, thereby improving prognosis by early detection and reducing costs.

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      Mentions: UC Irvine
    2. Quantitative angle-insensitive flow measurement using relative standard deviation OCT

      Quantitative angle-insensitive flow measurement using relative standard deviation OCT

      Incorporating different data processing methods, optical coherence tomography (OCT) has the ability for high-resolution angiography and quantitative flow velocity measurements. However, OCT angiography cannot provide quantitative information of flow velocities, and the velocity measurement based on Doppler OCT requires the determination of Doppler angles, which is a challenge in a complex vascular network. In this study, we report on a relative standard deviation OCT (RSD-OCT) method which provides both vascular network mapping and quantitative information for flow velocities within a wide range of Doppler angles. The RSD values are angle-insensitive within a wide range of angles, and a nearly linear ...

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      Mentions: UC Irvine
    3. Fully integrated optical coherence tomography, ultrasound, and indocyanine green-based fluorescence tri-modality system for intravascular imaging

      Fully integrated optical coherence tomography, ultrasound, and indocyanine green-based fluorescence tri-modality system for intravascular imaging

      We present a tri-modality imaging system and fully integrated tri-modality probe for intravascular imaging. The tri-modality imaging system is able to simultaneously acquire optical coherence tomography (OCT), ultrasound (US), and fluorescence imaging. Moreover, for fluorescence imaging, we used the FDA-approved indocyanine green (ICG) dye as the contrast agent to target lipid-loaded macrophages. We conducted imaging from a male New Zealand white rabbit to evaluate the performance of the tri-modality system. In addition, tri-modality images of rabbit aortas were correlated with hematoxylin and eosin (H&E) histology to check the measurement accuracy. The fully integrated miniature tri-modality probe, together with the ...

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      Mentions: UC Irvine
    4. Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory

      Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory

      To extend our understanding of tear film dynamics for the management of dry eye disease, we propose a method to optically sense the tear film and estimate simultaneously the thicknesses of the lipid and aqueous layers. The proposed method, SDT-OCT, combines ultra-high axial resolution optical coherence tomography (OCT) and a robust estimator based on statistical decision theory (SDT) to achieve thickness measurements at the nanometer scale. Unlike conventional Fourier-domain OCT where peak detection of layers occurs in Fourier space, in SDT-OCT thickness is estimated using statistical decision theory directly on the raw spectra acquired with the OCT system. In this ...

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    1-4 of 4
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  2. Topics in the News

    1. (3 articles) UC Irvine
    2. (1 articles) University of Rochester
    3. (1 articles) University of Arizona
    4. (1 articles) University of North Carolina
    5. (1 articles) Zhejiang University
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    Measurement of a multi-layered tear film phantom using optical coherence tomography and statistical decision theory Fully integrated optical coherence tomography, ultrasound, and indocyanine green-based fluorescence tri-modality system for intravascular imaging Quantitative angle-insensitive flow measurement using relative standard deviation OCT Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature Post-Doctoral and Graduate Student Research Positions at the University of Illinois Urbana-Champaign Multiscale correlation of microvascular changes on optical coherence tomography angiography with retinal sensitivity in diabetic retinopathy Macrophage targeted theranostic strategy for accurate detection and rapid stabilization of the inflamed high-risk plaque PERSONALIZED CHARACTERISTICS OF MORPHOMETRIC AND FUNCTIONAL PARAMETERS OF RETINA IN ARTERIAL HYPERTENTION ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY-ANGIOGRAPHY DATA Coherence function-encoded optical palpation Systems, methods, and media for multiple reference arm spectral domain optical coherence tomography Monitoring dissolution of a dosage form in progress during dissolution by low coherence interferometry Two Postdoc Openings at the Physical Optics and Biophotonics Group at Institute of Physical Chemistry, Warsaw, Poland