1. Articles from Matthew J. Stainer

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    1. Monitoring of strain-dependent responsiveness to TLR activation in the mouse anterior segment using SD-OCT

      Monitoring of strain-dependent responsiveness to TLR activation in the mouse anterior segment using SD-OCT

      Purpose: To determine whether spectral-domain optical coherence tomography (SD-OCT) can be used to longitudinally monitor inflammation in the mouse anterior segment and to identify any strain-dependent differences in responsiveness to distinct toll-like receptor ligands. Methods: Corneal inflammation was induced in BALB/c and C57BL/6 mice following central corneal abrasions and topical application of saline, toll-like receptor (TLR)-4 ligand, lipopolysaccharide (LPS) or TLR9 ligand, CpG-ODN (CpG). Anterior-segment images were captured using SD-OCT at baseline, 24 hours and one-week post-treatment. Corneal thickness, stromal haze and the number of keratic precipitates (KP) and anterior chamber (AC) cells were longitudinally compared to ...

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  2. Topics in the News

    1. (1 articles) University of Melbourne
    2. (1 articles) University of Bologna
    3. (1 articles) University of Cambridge
    4. (1 articles) FDA
    5. (1 articles) Notal Vision
    6. (1 articles) Topcon Medical Systems
    7. (1 articles) Tomey Corporation
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