1. Articles from Hao Chen

    1-9 of 9
    1. Towards multi-center glaucoma OCT image screening with semi-supervised joint structure and function multi-task learning

      Towards multi-center glaucoma OCT image screening with semi-supervised joint structure and function multi-task learning

      Glaucoma is the leading cause of irreversible blindness in the world. Structure and function assessments play an important role in diagnosing glaucoma. Nowadays, Optical Coherence Tomography (OCT) imaging gains increasing popularity in measuring the structural change of eyes. However, few automated methods have been developed based on OCT images to screen glaucoma. In this paper, we are the first to unify the structure analysis and function regression to distinguish glaucoma patients from normal controls effectively. Specifically, our method works in two steps: a semi-supervised learning strategy with smoothness assumption is first applied for the surrogate assignment of missing function regression ...

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    2. Axial length measurement and detection rates using a swept-source optical coherence tomography based biometer in the presence of a dense vitreous hemorrhage

      Axial length measurement and detection rates using a swept-source optical coherence tomography based biometer in the presence of a dense vitreous hemorrhage

      Purpose: To evaluate axial length (AL) measurements and detection rates using a swept-source optical coherence tomography (SS-OCT) biometer (OA-2000, Tomey, Japan) compared with the IOLMaster (v5.4, Carl Zeiss Meditec AG, Germany), Lenstar (v2.1, Haag-Streit, Switzerland) and ultrasound (US) measurements in eyes with vitreous hemorrhage (VH). Setting: Eye Hospital of Wenzhou Medical University, Wenzhou, China. Design: Comparative evaluation of a diagnostic test or technology. Methods: The main outcomes were AL measurement failure rate and agreement in AL measurements in patients with VH. The Bland-Altman method was used to assess the agreement between devices. Results: In total, 40 eyes were ...

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    3. Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis

      Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis

      Background Spectral-domain optical coherence tomography (SDOCT) can be used to detect glaucomatous optic neuropathy, but human expertise in interpretation of SDOCT is limited. We aimed to develop and validate a three-dimensional (3D) deep-learning system using SDOCT volumes to detect glaucomatous optic neuropathy. Methods We retrospectively collected a dataset including 4877 SDOCT volumes of optic disc cube for training (60%), testing (20%), and primary validation (20%) from electronic medical and research records at the Chinese University of Hong Kong Eye Centre (Hong Kong, China) and the Hong Kong Eye Hospital (Hong Kong, China). Residual network was used to build the 3D ...

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    4. Unifying Structure Analysis and Surrogate-driven Function Regression for Glaucoma OCT Image Screening

      Unifying Structure Analysis and Surrogate-driven Function Regression for Glaucoma OCT Image Screening

      Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of automated methods has been developed based on OCT images for glaucoma study. In this paper, we present a novel framework to effectively classify glaucoma OCT images from normal ones. A semi-supervised learning strategy with smoothness assumption is applied for surrogate assignment of missing function regression labels. Besides, the proposed multi-task learning network is capable of exploring the structure and function relationship from the OCT image and visual ...

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    5. Comprehensive Comparison of Axial Length Measurement With Three Swept-Source OCT-Based Biometers and Partial Coherence Interferometry

      Comprehensive Comparison of Axial Length Measurement With Three Swept-Source OCT-Based Biometers and Partial Coherence Interferometry

      PURPOSE: To compare axial length measurements (and failure rate) of three swept-source optical coherence tomography (SS-OCT)–based biometers: IOLMaster 700 (Carl Zeiss Meditec, Jena, Germany), OA-2000 (Tomey, Nagoya, Japan), and Argos (Movu Inc., Komaki, Japan) to those provided by a partial coherence interferometry (PCI)–based optical biometer (IOLMaster v5.4 [Carl Zeiss Meditec]). METHODS: A total of 119 patients (171 eyes) undergoing cataract surgery were enrolled. Axial length was measured with the four biometers in a random order. Chi-square analysis was used to determine whether statistically significant differences in success rates were found between biometers. Within-subject standard deviation (S w ...

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    6. Precision of a new ocular biometer in eyes with cataract using swept source optical coherence tomography combined with Placido-disk corneal topography

      Precision of a new ocular biometer in eyes with cataract using swept source optical coherence tomography combined with Placido-disk corneal topography

      The present study was to assess the precision (repeatability and reproducibility) of a new optical biometer (OA-2000, Tomey, Japan) based on swept-source optical coherence tomography (SS-OCT) and Placido disk topography in eyes with cataracts. Seventy-eight eyes from seventy-eight patients with cataracts were evaluated. Axial length (AL), anterior chamber depth (ACD), keratometry (K) over a 2.5 mm and 3.0 mm diameter, lens thickness (LT), central corneal thickness (CCT) and white-to-white (WTW) distance were measured by 2 skilled operators. OA-2000 measurements were highly repeatable and reproducible for all parameters (intraclass correlation, 0.925 to 1.000). OA-2000 derived K-values with ...

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    7. Repeatability and interobserver reproducibility of a new optical biometer based on swept-source optical coherence tomography and comparison with IOLMaster

      Repeatability and interobserver reproducibility of a new optical biometer based on swept-source optical coherence tomography and comparison with IOLMaster

      Objective To evaluate the precision of the measurements in healthy subjects obtained with a new optical biometer (OA-2000, Tomey, Nagoya, Japan) using swept-source optical coherence tomography (SS-OCT) and compare these measurements with those provided by the IOLMaster v5.4 (Carl Zeiss Meditec AG, Jena, Germany) using partial coherence interferometry (PCI). Methods Axial length (AL), keratometry (K) over 2.5 mm and 3.0 mm diameters, anterior chamber depth (ACD) (corneal epithelium to lens), lens thickness (LT), central corneal thickness and corneal diameter (CD) were measured with SS-OCT by two experienced operators. Intraobserver repeatability and interobserver reproducibility were assessed. AL, ACD ...

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    8. Corneal Power Measurement Obtained by Fourier-Domain Optical Coherence Tomography: Repeatability, Reproducibility, and Comparison With Scheimpflug and Automated Keratometry Measurements

      Corneal Power Measurement Obtained by Fourier-Domain Optical Coherence Tomography: Repeatability, Reproducibility, and Comparison With Scheimpflug and Automated Keratometry Measurements

      Purpose: To assess the repeatability and reproducibility of corneal power values obtained by a Fourier-domain optical coherence tomography (FD-OCT) system (RTVue) and to compare them with the values obtained by a Scheimpflug camera system (Pentacam HR) and by automated keratometry (IOL Master). Methods: Thirty-two eyes from 32 healthy subjects were included in this prospective study. Two experienced observers measured each eye 3 consecutive times with the Pentacam, IOLMaster, and RTVue centered on either the pupil or corneal vertex. The conventional keratometry equivalent (CKE) and anterior (Ka), posterior (Kp), and net (Kn) corneal power values were determined. Results: The corneal power ...

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    9. Anterior chamber depth measurements using Scheimpflug imaging and optical coherence tomography: Repeatability, reproducibility, and agreement

      Anterior chamber depth measurements using Scheimpflug imaging and optical coherence tomography: Repeatability, reproducibility, and agreement

      Purpose To determine the repeatability, reproducibility, and agreement of anterior chamber depth (ACD) measurements obtained with 3 Scheimpflug cameras and an anterior segment optical coherence tomography (AS-OCT) device. Setting Eye Hospital of Wenzhou Medical University, Zhejiang, China. Design Observational cross-sectional study. Methods Two observers took 3 consecutive measurements in healthy right eyes using each device to assess intraoperator repeatability. The mean values obtained at different sessions by the first operator were used to determine the intersession reproducibility. Three consecutive measurements obtained by the first operator at the first session were averaged and used to assess agreement. Results The ACD measurements ...

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    1-9 of 9
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    1. (5 articles) Wenzhou Medical College
    2. (4 articles) Giacomo Savini
    3. (3 articles) The Chinese University of Hong Kong
    4. (3 articles) Tomey Corporation
    5. (2 articles) Stanford University
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    Anterior chamber depth measurements using Scheimpflug imaging and optical coherence tomography: Repeatability, reproducibility, and agreement Corneal Power Measurement Obtained by Fourier-Domain Optical Coherence Tomography: Repeatability, Reproducibility, and Comparison With Scheimpflug and Automated Keratometry Measurements Repeatability and interobserver reproducibility of a new optical biometer based on swept-source optical coherence tomography and comparison with IOLMaster Precision of a new ocular biometer in eyes with cataract using swept source optical coherence tomography combined with Placido-disk corneal topography Comprehensive Comparison of Axial Length Measurement With Three Swept-Source OCT-Based Biometers and Partial Coherence Interferometry Unifying Structure Analysis and Surrogate-driven Function Regression for Glaucoma OCT Image Screening Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis Axial length measurement and detection rates using a swept-source optical coherence tomography based biometer in the presence of a dense vitreous hemorrhage Towards multi-center glaucoma OCT image screening with semi-supervised joint structure and function multi-task learning Optical coherence tomography features of neovascularization in proliferative diabetic retinopathy: a systematic review Retinal microvascular metrics in untreated essential hypertensives using optical coherence tomography angiography Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study