1. Articles from Ing-Chou Lai

    1-5 of 5
    1. Segmental inner macular layer analysis with spectral-domain optical coherence tomography for early detection of normal tension glaucoma

      Segmental inner macular layer analysis with spectral-domain optical coherence tomography for early detection of normal tension glaucoma

      Purpose To segment the inner macular layers (IML) and compare the discriminating abilities of the macular and peripapillary retinal nerve fiber layer (mRNFL and pRNFL, respectively) thicknesses in patients with early-stage normal tension glaucoma (NTG). Design Cross-sectional study Methods Forty-nine normal subjects and 69 preperimetric glaucoma (PPG) and 60 NTG patients were enrolled. Spectral-domain optical coherence tomography (SD-OCT) was used to obtain pRNFL and macular thickness parameters and segment the IML in all subjects. Area under the receiver operating characteristic (AUROC) curves were used to compare the diagnostic capabilities of different parameters. Results The pRNFL, total macular layer (TML), mRNFL ...

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    2. Analysis of peripapillary retinal nerve fiber layer and inner macular layers by spectral-domain optical coherence tomography for detection of early glaucoma

      Analysis of peripapillary retinal nerve fiber layer and inner macular layers by spectral-domain optical coherence tomography for detection of early glaucoma

      AIM : To analyze the diagnostic capabilities of peripapillary retinal nerve fiber layer (pRNFL) thickness and segmented inner macular layer (IML) thickness measured by spectral-domain optical coherence tomography for detection of early glaucoma. METHODS : Fifty-three patients with primary open angle glaucoma (POAG), 60 patients with normal tension glaucoma (NTG) and 32 normal control subjects were enrolled. Thicknesses of pRNFL, total macular layers (TML), and the IML, including macular RNFL (mRNFL) and macular ganglion cell layer (mGCL) were assessed. The areas under the receiver operating characteristic curves (AROC) were calculated to compare the diagnostic power of different parameters. RESULTS : There were no ...

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    3. Diagnostic capability of peripapillary retinal nerve fiber layer parameters in time-domain versus spectral-domain optical coherence tomography for assessing glaucoma in high myopia

      Diagnostic capability of peripapillary retinal nerve fiber layer parameters in time-domain versus spectral-domain optical coherence tomography for assessing glaucoma in high myopia

      AIM : To evaluate and compare the diagnostic capabilities of peripapillary retinal nerve fiber layer (p-RNFL) parameters of Spectralis optical coherence tomography (OCT) versus Stratus OCT to detect glaucoma in patients with high myopia. METHODS : This is a retrospective, cross-sectional study. Sixty highly myopic eyes of 60 patients were enrolled, with 30 eyes in the glaucoma group and 30 eyes in the control group. All eyes received peripapillary imaging of the optic disc using Stratus and Spectralis OCT. Areas under the receiver operating characteristic curve (AUROC) and the sensitivity at specificity of >80% and >95% for p-RNFL parameters obtained using the ...

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    4. Macular Diagnostic Ability in OCT for Assessing Glaucoma in High Myopia

      Macular Diagnostic Ability in OCT for Assessing Glaucoma in High Myopia

      Purpose: To compare the diagnostic abilities of spectral-domain optical coherence tomography (SD-OCT; Spectralis OCT) and time-domain OCT (TD-OCT; Stratus OCT). Changes in macular parameters in highly myopic eyes of glaucoma patients and highly myopic eyes of glaucoma suspects were evaluated and compared. Methods: We collected data from 72 highly myopic eyes (spherical equivalent, <=-6.0D). Forty-one eyes had perimetric glaucoma and 31 eyes were suspected to have glaucoma (control group). All eyes underwent SD-OCT and TD-OCT imaging. Area under the receiver operating characteristic (AUROC) curve and sensitivity were examined on macular volume and thickness parameters at a fixed specificity and ...

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    5. Macular parameters of Stratus optical coherence tomography for assessing glaucoma in high myopia

      Macular parameters of Stratus optical coherence tomography for assessing glaucoma in high myopia

      Background The aim was to assess the macular parameters of glaucoma in highly myopic subjects. Methods In a retrospective study, we enrolled 72 highly myopic eyes (spherical equivalent up to -6.00 D), of which 31 had early to moderate glaucoma and 41 formed a control group. The diagnosis of early to moderate glaucoma was based on glaucomatous visual-field defects with a mean deviation better than -12 dB. All patients underwent imaging with Stratus optical coherence tomography. We subsequently performed analysis for macular volume and thickness parameters between two groups. Results Using Stratus optical coherence tomography, we found significantly lower ...

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    1-5 of 5
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  2. Topics in the News

    1. (4 articles) Chang Gung University
    2. (4 articles) Sun Yat-Sen University
    3. (3 articles) Zeiss Stratus OCT
    4. (2 articles) Carl Zeiss Meditec
    5. (2 articles) Heidelberg Spectralis
    6. (1 articles) Heidelberg Engineering
    7. (1 articles) Medical University of Vienna
    8. (1 articles) University of Florence
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    12. (1 articles) Srinivas R. Sadda
    13. (1 articles) Xincheng Yao
    14. (1 articles) Bo Yu
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