1. Articles from Darius M. Moshfeghi

    1-3 of 3
    1. Speckle-modulating optical coherence tomography in living mice and humans

      Speckle-modulating optical coherence tomography in living mice and humans

      Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo . As a consequence, OCT is susceptible to coherent noise (speckle noise), which imposes significant limitations on its diagnostic capabilities. Here we show speckle-modulating OCT (SM-OCT), a method based purely on light manipulation that virtually eliminates speckle noise originating from a sample. SM-OCT accomplishes this by creating and averaging an unlimited number of scans with uncorrelated speckle patterns without compromising spatial resolution. Using SM-OCT, we reveal small structures in the tissues of living animals, such as ...

      Read Full Article
    2. High-resolution contrast-enhanced optical coherence tomography in mice retinae

      High-resolution contrast-enhanced optical coherence tomography in mice retinae

      Optical coherence tomography (OCT) is a noninvasive interferometric imaging modality providing anatomical information at depths of millimeters and a resolution of micrometers. Conventional OCT images limit our knowledge to anatomical structures alone, without any contrast enhancement. Therefore, here we have, for the first time, optimized an OCT-based contrast-enhanced imaging system for imaging single cells and blood vessels in vivo inside the living mouse retina at subnanomolar sensitivity. We used bioconjugated gold nanorods (GNRs) as exogenous OCT contrast agents. Specifically, we used anti-mouse CD45 coated GNRs to label mouse leukocytes and mPEG-coated GNRs to determine sensitivity of GNR detection in vivo ...

      Read Full Article
    3. Spectral-Domain Optical Coherence Tomography of Emulsified Subretinal Silicone Oil Presenting as a Macular Inverted Pseudohypopyon

      Spectral-Domain Optical Coherence Tomography of Emulsified Subretinal Silicone Oil Presenting as a Macular Inverted Pseudohypopyon

      The authors present a rare case of an inverted pseudohypopyon due to subretinal emulsified silicone oil in the macula of a patient who underwent pars plana vitrectomy surgery for repair of retinal detachment with proliferative vitreoretinopathy 1 year prior to presentation of this finding. The patient’s predisposing diagnosis is pathologic myopia.

      Read Full Article
    1-3 of 3
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (3 articles) Stanford University
    2. (2 articles) Adam de la Zerda
    3. (2 articles) Debasish Sen
    4. (2 articles) Elliott D. SoRelle
    5. (2 articles) Orly Liba
    6. (1 articles) Optovue
    7. (1 articles) Thorlabs
    8. (1 articles) Bausch & Lomb
  3. Popular Articles

  4. Picture Gallery

    Spectral-Domain Optical Coherence Tomography of Emulsified Subretinal Silicone Oil Presenting as a Macular Inverted Pseudohypopyon High-resolution contrast-enhanced optical coherence tomography in mice retinae Speckle-modulating optical coherence tomography in living mice and humans Relationship between optic nerve head and retinal nerve fiber layer with central corneal thickness in primary open angle glaucoma: A three-dimensional optical coherence tomography study Automated macular segmentation with spectral domain optical coherence tomography in the fellow eyes of patients with unilateral retinal vein occlusion Corneal Curvature Measurements Utilizing a New Swept-source Optical Coherence Tomography Tomey OA-2000® and Comparison With IOL Master® 500 in Pterygium Patients Optical coherence tomography angiography features of paracentral acute middle maculopathy in a young female in sub-Saharan Africa: A case report Retinal optical coherence tomography image enhancement via deep learning Supercontinuum source-based multi-contrast optical coherence tomography for rat retina imaging Reproducibility of optical coherence tomography in vein grafts used for coronary revascularization RELATIONSHIP BETWEEN ABNORMALITIES OF PHOTORECEPTOR MICROSTRUCTURES AND MICROVASCULAR STRUCTURES DETERMINED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EYES WITH BRANCH RETINAL VEIN OCCLUSION Visualization of the pulp chamber roof and residual dentin thickness by spectral-domain optical coherence tomography in vitro