1. Articles from S. Guo

    1-2 of 2
    1. Optically based-indentation technique for acute rat brain tissue slices and thin biomaterials

      Optically based-indentation technique for acute rat brain tissue slices and thin biomaterials
      Currently, micro-indentation testing of soft biological materials is limited in its capability to test over long time scales due to accumulated instrumental drift errors. As a result, there is a paucity of measures for mechanical properties such as the equilibrium modulus. In this study, indentation combined with optical coherence tomography (OCT) was used for mechanical testing of thin tissue slices. OCT was used to measure the surface deformation profiles after placing spherical beads onto submerged test samples. Agarose-based hydrogels at low-concentrations (w/v, 0.3–0.6%) and acute rat brain tissue slices were tested using this technique over a ...
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    2. Laryngeal epithelial thickness: a comparison between optical coherence tomography and histology

      Objectives: Optical coherence tomography, an imaging modality using near-infrared light, produces cross-sectional tissue images with a lateral pixel resolution of 10 μm. However, normative data is first needed on epithelial thickness for lesion characterisation, and, to date, little exists. The purpose of our study is to measure normal laryngeal epithelial thickness by in vivo optical coherence tomography, and compare these values to those obtained from fixed ex-vivo laryngectomy specimens. Design and Setting: Prospective at a single medical center in California, United States. Participants: A total of 116 patients undergoing operative endoscopy. Main outcome measures: Optical coherence tomography images of clinically ...
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    1-2 of 2
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  2. Topics in the News

    1. (6 articles) National Institutes of Health
    2. (2 articles) Shuguang Guo
    3. (2 articles) UC Irvine
    4. (2 articles) Oregon Health & Science University
    5. (2 articles) Zhongping Chen
    6. (2 articles) Yifan Jian
    7. (1 articles) UC Irvine
    8. (1 articles) Roger L. Crumley
    9. (1 articles) Mai Gu
    10. (1 articles) Meghann L. Kaiser
    11. (1 articles) Zhongping Chen
    12. (1 articles) David E. Vokes
    13. (1 articles) Marc Rubinstein
    14. (1 articles) William B. Armstrong
    15. (1 articles) James M. Ridgway
    16. (1 articles) UCLA
    17. (1 articles) University of Lübeck
    18. (1 articles) Pusan National University
    19. (1 articles) Evelyn Regar
    20. (1 articles) Antonios Karanasos
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    Optically based-indentation technique for acute rat brain tissue slices and thin biomaterials The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Association of systemic inflammatory biomarkers with morphological characteristics of the coronary atherosclerotic plaque by intravascular optical coherence tomography. OCT angiography improves views of retina blood flow Real-time retinal layer segmentation of OCT Volumes with GPU and Deep learning Baylor College of Medicine Receives a 2020 NIH Grant for Biomechanics of Early Mammalian Cardiogenesis University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality Oregon Health and Sciences University Receives a 2020 NIH Grant  for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography for Retinopathy of Prematurity UC Irvine Receives a 2020 NIH Grant for In Vivo Imaging and Quantification of Cilia Beating Dynamics Using Phase-Resolved Optical Imaging Technology UC Irvine Receives a 2020 NIH Grant for Phased Resolved ARF Optical Coherence Elastography for Intravascular Imaging Lumedica Incorporated Receives a 2020 NIH Grant for Low Cost Retinal Optical Coherence Tomography for Point of Care Use